A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium has been isolated from the mouth, urine, feces, and infections of the mouth, soft tissue, respiratory tract, urogenital tract, and intestinal tract. It is pathogenic, but usually in association with other kinds of organisms.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Microbial Sensitivity Tests
Drug Resistance, Microbial
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods. Organisms of this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings in 1990 indicated the need to separate them from other Bacteroides species, and hence, this new genus was established.
A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.
Gram-Negative Anaerobic Bacteria
Amino Acid Sequence
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Escherichia coli O157
A verocytotoxin-producing serogroup belonging to the O subfamily of Escherichia coli which has been shown to cause severe food-borne disease. A strain from this serogroup, serotype H7, which produces SHIGA TOXINS, has been linked to human disease outbreaks resulting from contamination of foods by E. coli O157 from bovine origin.
Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
DNA Transposable Elements
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods or coccobacilli. Organisms in this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Bacteroides species, and hence, this new genus was created.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Gene Expression Regulation, Bacterial
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Colony Count, Microbial
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Bacterial Outer Membrane Proteins
Escherichia coli K12
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
Sequence Analysis, DNA
A genus of gram-positive, rod-shaped bacteria found in cavities of man and animals, animal and plant products, infections of soft tissue, and soil. Some species may be pathogenic. No endospores are produced. The genus Eubacterium should not be confused with EUBACTERIA, one of the three domains of life.
Escherichia coli) and anaerobic bacteria (e.g., Bacteroides fragilis). Fecal peritonitis results from the presence of faeces in ...
Lactobacilli have been shown to inhibit in vitro growth of pathogenic microorganisms, e.g. Bacteroides fragilis, Escherichia ... such as Escherichia coli. Mycoplasma and Ureaplasma are frequently found in the vagina. Some of the obligate and facultative ... and Bacteroides spp., Fusobacterium spp., Gardnerella vaginalis, Mobiluncus, Prevotella spp., and Gram-negative enteric ...
An example of this is Appendicitis, which is caused by Bacteroides fragilis and Escherichia coli. The second is an iatrogenic ... Escherichia coli, Clostridium botulinum, and Salmonella spp.) Viruses and related agents such as viroids (HIV, Rhinovirus, ... Escherichia coli, and tape worms. Most of these pathogens cause gastroenteritis. Sexual transmission, with the resulting ...
Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Clostridium perfringens, and ... Escherichia coli: 0.015 μg/mL - 4 μg/mL Klebsiella pneumoniae: 0.06 μg/mL - 16 μg/mL Staphylococcus aureus (methicillin- ... and Bacteroides fragilis. Tigecycline is indicated for treatment of complicated intra-abdominal infections caused by; ... Escherichia coli, vancomycin-susceptible Enterococcus faecalis, methicillin-resistant Staphylococcus aureus (MRSA), ...
Bacteria recovered from TOAs are Escherichia coli, Bacteroides fragilis, other Bacteroides species, Peptostreptococcus, ...
Fumarate reductase (quinol)
... and Bacteroides fragilis. Each of these organisms has slightly different gene regulation and function in addition to different ... Iverson TM, Luna-Chavez C, Croal LR, Cecchini G, Rees DC (May 2002). "Crystallographic studies of the Escherichia coli quinol- ... "Fumarate reductase is a major contributor to the generation of reactive oxygen species in the anaerobe Bacteroides fragilis". ... Succinate dehydrogenase Iverson TM, Luna-Chavez C, Cecchini G, Rees DC (June 1999). "Structure of the Escherichia coli fumarate ...
Bacteroides spp., including B. fragilis Enterobacter spp. Escherichia coli Haemophilus influenzae Klebsiella species Morganella ...
... fucosyllactose in engineered Escherichia coli by expressing putative α-1,2-fucosyltransferase, WcfB from Bacteroides fragilis ... Chin, Young-Wook; Seo, Nari; Kim, Jae-Han; Seo, Jin-Ho (2016). "Metabolic engineering of Escherichia coli to produce 2'‐ ... using engineered Escherichia coli". Microbial Cell Factories. 11: 48. doi:10.1186/1475-2859-11-48. PMC 3442965. PMID 22545760. ... fucosyllactose in engineered Escherichia coli BL21star (DE3) by modulation of lactose metabolism and fucosyltransferase". ...
Runting-stunting syndrome in broilers
Bacteroides fragilis and Bacillus licheniformis, often isolated in affected birds. Reovirus vaccines are advocated (in dams or ... bacteria like Escherichia coli, Proteus mirabilis, Enterococcus faecium, Staphylococcus cohnii, Clostridium perfringens, ...
... and NADP-dependent 7alpha-hydroxysteroid dehydrogenases from bacteroides fragilis". Biochimica et Biophysica Acta (BBA) - ... Haslewood ES, Haslewood GA (July 1976). "The specificity of a 7 alpha-hydroxy steroid dehydrogenase from Escherichia coli". The ... Macdonald IA, Williams CN, Mahony DE (June 1973). "7Alpha-hydroxysteroid dehydrogenase from Escherichia coli B: preliminary ...
Escherichia coli: 0.06 µg/mL Bacteroides fragilis: ≤0.06 µg/mL - 512 µg/mL Clostridium perfringens: 1 µg/mL - 4 µg/mL Stork CM ... Notable species include Bacteroides, Streptococcus, and Escherichia. The following represents MIC susceptibility data for a few ...
Gynecological infections - Caused by beta-lactamase producing strains of E. coli and Bacteroides sp. (including B. fragilis). ... Urinary tract infections - pyelonephritis, cystitis caused by Escherichia coli, Proteus mirabilis, Klebsiella and ...
Anaerobes (MIC 0.03-0.3 mg/mL): Bacteroides species (including B. fragilis), Fusobacteria, Clostridium species, ... Gram-negative bacteria (MIC of 0.5-5 mg/mL): Aerobacter species, Citrobacter species, Enterobacter species, Escherichia coli, ...
Bacteroides distasonis Bacteroides fragilis Bacteroides ovatus Bacteroides thetaiotaomicron Bacteroides uniformis Bacteria that ... Gram-negative aerobes Escherichia coli Haemophilus influenzae Klebsiella pneumoniae Moraxella catarrhalis Proteus mirabilis ...
Escherichia coli, Proteus mirabilis, Bacteroides fragilis and Peptostreptococcus species. Imipenem/cilastatin was approved for ...
Jones DT, Robb FT, Woods DR (December 1980). "Effect of oxygen on Bacteroides fragilis survival after far-ultraviolet ... Smith KC, Martignoni KD (December 1976). "Protection of Escherichia coli cells against the lethal effects of ultraviolet and x ...
List of clinically important bacteria
... stearothermophilus Bacillus subtilis Bacillus thuringiensis Bacteroides Bacteroides fragilis Bacteroides gingivalis Bacteroides ... avium Enterococcus durans Enterococcus faecalis Enterococcus faecium Enterococcus gallinarum Enterococcus maloratus Escherichia ... previously called Bacteroides melaninogenicus) Pseudomonas aeruginosa Rhizobium radiobacter Rickettsia Rickettsia prowazekii ...
As listed, it has modest activity against the anaerobic Bacteroides fragilis. The following represents MIC susceptibility data ... pyogenes Escherichia coli Haemophilus influenzae Neisseria gonorrhoeae and N. meningitidis Klebsiella spp. Burkholderia cepacia ... Bacteroides spp. Fusobacterium spp. Notable organisms against which cefotaxime is not active include Pseudomonas and ...
... s generally exhibit good activity against anaerobes such as Bacteroides fragilis. Like other beta lactam antibiotics ... Between 2007 and 2011, the percentage of Escherichia coli isolates from Canadian hospitals that produce extended spectrum beta ... and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: ... including Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Citrobacter freundii, Proteus mirabilis, and Serratia ...
Shah, H.N.; Collins, M.D. (1989). "Proposal to restrict the genus Bacteroides (Castellani and Chalmers) to Bacteroides fragilis ... corresponding to positions 29 to 1504 of the Escherichia coli 16s rRNA). Sequence similarity calculations revealed that the ... nonpigmented species of the Bacteroides fragilis group. B. pneumosintes differs from this genus as defined by Shah and Collins ... The species was later placed in the genus Dialister and subsequently transferred to the genus Bacteroides in 1970 (8). During ...
Bacteroides fragilis group is rarely recovered in these infections compared to intra-abdominal infection. Actinomyces spp. and ... an initial stages of generalized peritonitis associated with Escherichia coli sepsis, and a later stages, in which intra ... Agents no longer recommended are: cefotetan and clindamycin ( Bacteroides fragilis group resistance) and ampicillin-sulbactam ( ... Bacteroides fragilis).Clostridium perfringens can cause of brain abscesses and meningitis following intracranial surgery or ...
List of MeSH codes (B03)
MeSH B03.140.094.152 - bacteroides MeSH B03.140.094.152.400 - Bacteroides fragilis MeSH B03.140.094.625 - Porphyromonas MeSH ... Escherichia coli MeSH B03.440.450.425.325.300.149 - Escherichia coli k12 MeSH B03.440.450.425.325.300.300 - Escherichia coli ... Bacteroides MeSH B03.440.425.410.194.152.400 - Bacteroides fragilis MeSH B03.440.425.410.194.625 - Porphyromonas MeSH B03.440. ... Escherichia coli MeSH B03.6188.8.131.52.100.049 - Escherichia coli k12 MeSH B03.6184.108.40.206.100.100 - Escherichia coli ...
... although resistance is increasing in Bacteroides fragilis.[medical citation needed] Most aerobic Gram-negative bacteria (such ... The X-ray crystal structures of clindamycin bound to ribosomes (or ribosomal subunits) derived from Escherichia coli, ... Anaerobic, Gram-negative rod-shaped bacteria, including some Bacteroides, Fusobacterium, and Prevotella, ... "Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug ...
Class III enzymes (GSIII) have, currently, only been found in Bacteroides fragilis and in Butyrivibrio fibrisolvens. It is a ... Hunt JB, Smyrniotis PZ, Ginsburg A, Stadtman ER (Jan 1975). "Metal ion requirement by glutamine synthetase of Escherichia coli ... Fisher R, Tuli R, Haselkorn R (June 1981). "A cloned cyanobacterial gene for glutamine synthetase functions in Escherichia coli ... "Some effects of adenylylation on the biosynthetic properties of the glutamine synthetase from Escherichia coli". Biochemistry. ...
Microbial symbiosis and immunity
For example, the human symbiont Bacteroides fragilis produces polysaccharide A (PSA), which binds to toll-like receptor 2 (TLR- ... Many bacteria cause inflammation in the gut including Escherichia coli, which replicate in macrophages and secretes cytokine ... Bacteroides thetaiotaomicron, a bacterial species in the ileum and colon, stimulates the gene encoding fucose, Fut2, in ... These data suggest that PSA secreted by B. fragilis suppresses the inflammatory process during colitis by leading to increased ...
... and Bacteroides fragilis strains having various resistance phenotypes". Antimicrobial Agents and Chemotherapy. 55 (5): 2390-4. ... Currently, some Citrobacter freundii, Enterobacter cloacae, Neisseria gonorrhoeae, and Escherichia coli strains are resistant ...
... and Bacteroides fragilis strains having various resistance phenotypes". Antimicrobial Agents and Chemotherapy. 55 (5): 2390-4. ... In these same studies, ceftolozane-tazobactam exhibited MIC90 values of ,1 μg/mL for Escherichia coli, Citrobacter koseri, ...
Other genera, such as Escherichia and Lactobacillus, are present to a lesser extent. Species from the genus Bacteroides alone ... for example Bacteroides fragilis and some Clostridia species appear to drive an anti-inflammatory response, while some ... About 99% of the large intestine and feces flora are made up of obligate anaerobes such as Bacteroides and Bifidobacterium. ... Some genera of bacteria, such as Bacteroides and Clostridium, have been associated with an increase in tumor growth rate, while ...
List of infectious diseases
Bacteroides fragilis. *Tannerella forsythia. *Capnocytophaga canimorsus. *Porphyromonas gingivalis. *Prevotella intermedia. ... Escherichia coli O157:H7, O111 and O104:H4 Hemorrhagic fever with renal syndrome (HFRS) Bunyaviridae family ...
List of parasites of humans
Dientamoeba fragilis intestines stool up to 10% in industrialized countries ingesting water or food contaminated with feces ... Escherichia coli: Enterotoxigenic. *Enteroinvasive. *Enterohemorrhagic. *O157:H7. *O104:H4 *Hemolytic-uremic syndrome ...
Escherichia coli) and anaerobic bacteria (e.g., Bacteroides fragilis). Fecal peritonitis results from the presence of faeces in ...
Liosta de ghalair thógálacha - Vicipéid
Escherichia coli O157:H7, O111 and O104:H4. Hemorrhagic fever with renal syndrome (HFRS). Bunyaviridae family. ... Ionfhabhtú Bacteroides. Géineas Bacteroides. Balantidiasis. Balantidium coli. Ionfhabhtú Baylisascaris. Géineas Baylisascaris. ... Dientamoeba fragilis. Diphtheria. Corynebacterium diphtheriae. Diphyllobothriasis. Diphyllobothrium. Dracunculiasis. ...
List of sequenced bacterial genomes
2004). "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation". PNAS. ... 2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot-2005". Nucleic Acids Res. 34 (1): 1-9. doi:10.1093 ... 2005). "Extensive DNA inversions in the B. fragilis genome control variable gene expression" (PDF). Science. 307 (5714): 1463-5 ... 1997). "The complete genome sequence of Escherichia coli K-12". Science. 277 (5331): 1453-74. doi:10.1126/science.277.5331.1453 ...
Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes |...
Characterization of the BatI (Bacteroides aerotolerance) operon in Bacteroides fragilis: isolation of a B. fragilis mutant with ... Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes. D ... Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes ... Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes ...
Cloning of Bacteroides fragilis plasmid genes affecting metronidazole resistance and ultraviolet survival in Escherichia coli. ...
Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli. | Journal of...
Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli.. T A Russo, J S ... We have cloned the Bacteroides fragilis TAL2480 neuraminidase (NANase) structural gene, nanH, in Escherichia coli. This was ... Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli. ... Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli. ...
Isolation and Characterization of BTF-37: Chromosomal DNA Captured from Bacteroides fragilis That Confers Self-Transferability...
Regions in Bacteroides plasmids pBFTM10 and pB8-51 that allow Escherichia coli-Bacteroides shuttle vectors to be mobilized by ... Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes. ... We observed autonomous transfer of BTF-37 from Bacteroides to Bacteroides, from Bacteroides to E. coli, and from E. coli to E. ... The Bacteroides fragilis BtgA mobilization protein binds to the oriT region of pBFTM10. J. Bacteriol.180:4922-4928. ...
RCSB PDB - 3P24: Structure of profragilysin-3 from Bacteroides fragilis
Organism(s): Bacteroides fragilis. *Expression System: Escherichia coli. *Mutation(s): No *Deposited: 2010-10-01 Released: 2010 ... Bacteroides fragilis. Mutation(s): 0 Gene Names: bft-3. EC: 220.127.116.11. ... Enterotoxigenic Bacteroides fragilis is the most frequent disease-causing anaerobe in the intestinal tract of humans and ... Enterotoxigenic Bacteroides fragilis is the most frequent disease-causing anaerobe in the intestinal tract of humans and ...
RCSB PDB - 2QZU: Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics...
Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics Consortium target ... Organism(s): Bacteroides fragilis (strain YCH46). *Expression System: Escherichia coli. *Deposited: 2007-08-17 Released: 2007- ... X-ray crystal structure of the putative sulfatase yidJ from Bacteroides fragilis.. Vorobiev, S.M., Abashidze, M., Seetharaman, ... Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics Consortium target ...
Effect of Bacteroides fragilis on the peritoneal clearance of Escherichia coli in mice - Fingerprint - Research @ Flinders
Multidrug-Resistant Bacteroides fragilis - Seattle, Washington, 2013
The fluid grew a pan-susceptible Escherichia coli, and antibiotics were narrowed to ceftriaxone. The leukocyte count improved ... Multidrug-Resistant Bacteroides fragilis - Seattle, Washington, 2013. The Bacteroides fragilis group consists of species of ... Species identification was confirmed as Bacteroides fragilis ssp. fragilis by biochemical testing, mass spectrometry, and ... Multidrug resistant Bacteroides fragilis recovered from blood and severe leg wounds caused by an improvised explosive device ( ...
Characterization of a recombinant Bacteroides fragilis sialidase expressed in Escherichia coli-Open Library Archives of Kagawa...
Characterization of a recombinant Bacteroides fragilis sialidase expressed in Escherichia coli. aaaaa. Shift-JIS. EUC-JP. UTF-8 ... The human gut commensal Bacteroides fragilis produces sialidases that remove a terminal sialic acid from host-derived ... Sialidase is considered to be involved in B. fragilis infection pathology. A native B. fragilis sialidase has been purified and ... In this study, we examined the enzymatic properties of the 60-kDa sialidase NanH1 of B. fragilis YCH46, which was prepared as a ...
Zerbaxa (Ceftolozane and Tazobactam for Injection): Uses, Dosage, Side Effects, Interactions, Warning
Bacteroides fragilis. Complicated Urinary Tract Infections, Including Pyelonephritis. Gram-Negative Bacteria. Escherichia coli ... Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Bacteroides fragilis, ... Escherichia coli. Haemophilus influenzae. Klebsiella oxytoca. Klebsiella pneumonia. Proteus mirabilis. Pseudomonas aeruginosa. ... Escherichia coli. Klebsiella oxytoca. Klebsiella pneumonia. Proteus mirabilis. Pseudomonas aeruginosa. Gram-Positive Bacteria. ...
Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure. - PubMed - NCBI
Canonical, Escherichia coli, -10 and -35 consensus sequences were not readily apparent. Mutations within the -7 motif indicated ... Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure.. Bayley DP1, Rocha ER, Smith CJ. ... There is little known about the sequences that mediate the initiation of transcription in Bacteroides fragilis, thus ...
Levofloxacin plus metronidazole administered once daily versus moxifloxacin monotherapy against a mixed infection of...
By using an in vitro pharmacodynamic model in duplicate, Escherichia coli and Bacteroides fragilis were exposed to peak ... By using an in vitro pharmacodynamic model in duplicate, Escherichia coli and Bacteroides fragilis were exposed to peak ... By using an in vitro pharmacodynamic model in duplicate, Escherichia coli and Bacteroides fragilis were exposed to peak ... By using an in vitro pharmacodynamic model in duplicate, Escherichia coli and Bacteroides fragilis were exposed to peak ...
What is the hallmark symptom of necrotizing fasciitis?
What are risk factors for necrotizing fasciitis?
InFocus: Avoid I&D for Bartholin Gland Abscess, and Try a Wo... : Emergency Medicine News
RFA-AI-14-011: Novel, Alternative Model Systems for Enteric Diseases (U19)
comprehensive stool analysis test results
Gram Negative Bacteria
Bacteremia and Septic Shock
Escherichia coli Bacteroides fragilis Streptococcus pyogenes Staphylococcus aureus Clostridium sp.. Polymicrobial infections ... Escherichia coli Klebsiella sp. Enterobacter sp. Proteus sp. Streptococcus pneumoniae Neisseria meningitidis Listeria ... Staphylococcus aureus and Streptococcus pneumoniae are the most common gram-positive isolates, whereas Escherichia coli, ... and less commonly by Escherichia coli. Approximately 2 of 1000 live-born infants are infected by S agalactiae (group B ...
Bartholin's Gland Abscess
A simple, rapid and sensitive presence/absence detection test for bacteriophage in drinking water.
Bacteroides fragilis. Coliphages / growth & development, isolation & purification. Escherichia coli. Evaluation Studies as ... Bacteriophage infecting the anaerobe Bacteroides fragilis subsp. fragilis HSP40 were detected after 8 h. Application of this ... The entire device was incubated in a water bath at 36 degrees C. Plaques of somatic bacteriophage infecting Escherichia coli ...
Table 2 - Edwardsiella tarda Bacteremia, Okayama, Japan, 2005-2016 - Volume 25, Number 10-October 2019 - Emerging Infectious...
AMP, ampicillin; B. fragilis, Bacteroides fragilis; CFP/SUL, cefoperazon-sulbactam; C. freundii, Citrobacter freundii; CFZ, ... Escherichia coli; FEP, cefepime; F. nucleatum, Fusobacterium nucleatum; GEN, gentamycin; IPM/CIL, imipenem-cilastatin; K. ... E. coli, B. fragilis (pus). Recovered. 2. 79/M. Liver abscess. Cardiovascular disease. CFP/SUL→IPM/CIL→PIP→MEP, CLI→MEM. 38. ... E. faecalis, E. faecium, C. freundii, Bacteroides sp. (pus). Recovered. 14. 84/F. Cholangitis. Cardiovascular disease, ...
Bacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales...
To determine if these T6SSs are able to target Escherichia coli, we tested three different strains as prey; the laboratory ... Type strains used for in vivo competition include Bacteroides ovatus ATCC 8484, Bacteroides dorei 5_1_36/04, Bacteroides ... Bacteroides caccae CL03T12C61, B. fragilis 2_1_16, and P. copri were antagonized by the 9343 ΔT6SS mutant in a non-T6SS manner ... GA3 loci are not contained on conserved ICE and are confined to Bacteroides fragilis. Unlike GA1 and GA2 T6SS loci, most GA3 ...
Necrotizing Fasciitis: Practice Essentials, Background, Pathophysiology
Cultures revealed Escherichia coli and Bacteroides fragilis. The diagnosis was perineal gangrene. View Media Gallery ... Cultures revealed Escherichia coli and Bacteroides fragilis. The diagnosis was perineal gangrene. View Media Gallery ... Bacteroides fragilis is usually noted as part of a mixed flora in combination with E coli. B fragilis does not directly cause ... Cultures revealed Escherichia coli and Bacteroides fragilis. The diagnosis was perineal gangrene. ...
Method to predict degradation of a landfill - U.S. Environmental Protection Agency EPA
Necrotizing Fasciitis Clinical Presentation: History, Physical Examination
Frontiers | The Diverse Functional Roles of Elongation Factor Tu (EF-Tu) in Microbial Pathogenesis | Microbiology
Bacteroides fragilis (Zakharzhevskaya et al., 2017), Cronobacter sakazakii (Alzahrani et al., 2015), Escherichia coli (Lee et ... 2017). Outer membrane vesicles secreted by pathogenic and nonpathogenic Bacteroides fragilis represent different metabolic ... Analysis of the outer membrane proteome and secretome of Bacteroides fragilis reveals a multiplicity of secretion mechanisms. ... Furano, A. V. (1975). Content of elongation factor Tu in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 72, 4780-4784. doi: ...
Free Laboratory Science Flashcards about Unit 4 Chapter 34
Unasyn (Ampicillin and Sulbactam): Side Effects, Interactions, Warning, Dosage & Uses
Clostridium species,† Peptococcus species,† Peptostreptococcus species, Bacteroides species, including B. fragilis. † These are ... Gynecological Infections caused by beta-lactamase producing strains of Escherichia coli,* and Bacteroides spp.* (including B. ... including K. pneumoniae*), Bacteroides spp. (including B. fragilis), and Enterobacter spp.*. ... Bacteroides fragilis,* Enterobacter spp.,* and Acinetobacter calcoaceticus.*. NOTE: For information on use in pediatric ...
Infecting Escherichia coliPeptostreptococcusKlebsiellaEnterococcusRevealed Escherichia coli and Bacteroides fragilisPseudomonasProteusAnaerobesStrainsEnterobacterStaphylococcusSpeciesPathogenicBacteriaAnaerobePrevotellaOrganismCharacterizationStrainAntibiotic resistanceVitroGeneGenesPneumoniaeRecombinantIsolatesFecalBacteriophagesShuttle vectorO157CulturesMoxifloxacinPlasmidProteins
Infecting Escherichia coli1
- The entire device was incubated in a water bath at 36 degrees C. Plaques of somatic bacteriophage infecting Escherichia coli strain CN13, could be detected within 3 h. (biomedsearch.com)
- The predominant anaerobes were Bacteroides fragilis group ( n = 9) and Peptostreptococcus sp. (asm.org)
- Intra-abdominal infections caused by Escherichia coli, Klebsiella pneumoniae, Bacteroides fragilis, Clostridium species or Peptostreptococcus species. (drugs.com)
- Cultures obtained at this time later grew out Escherichia coli, Peptococcus asacrolyticus, Peptostreptococcus intermedius, and Bacteroides fragilis. (healio.com)
- Cultures obtained at the time of surgery revealed Bacteroides fragilis and Peptostreptococcus anaerobius. (healio.com)
- The control strains used were Bacteroides fragilis (ATCC 10584) and Peptostreptococcus anaerobius (ATCC 27337). (inchem.org)
- Intra-Abdominal Infections caused by beta-lactamase producing strains of Escherichia coli , Klebsiella spp. (rxlist.com)
- Bone and joint infections caused by Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae or Enterobacter species. (drugs.com)
- Complicated intra-abdominal infections caused by Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Enterococcus faecalis (vancomycin-susceptible isolates), Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus anginosus grp. (centerwatch.com)
- Escherichia coli (55.2%) and Klebsiella pneumoniae (23.0%) were the most common organisms isolated from the blood cultures. (springer.com)
- The causative organisms of BTIs usually originate from the gut flora, including Gram-negative bacteria (70-80%) such as Escherichia coli and Klebsiella spp. (springer.com)
- Complicated skin and skin structure infections caused by Escherichia coli, Enterococcus faecalis (vancomycin-susceptible isolates), Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus agalactiae, Streptococcus anginosus grp. (centerwatch.com)
- The control strains used were Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212), and Proteus mirabilis (ATCC 14273). (inchem.org)
Revealed Escherichia coli and Bacteroides fragilis1
- Cultures revealed Escherichia coli and Bacteroides fragilis. (medscape.com)
- Cultures revealed gram-negative Pseudomonas species and Bacteroides fragilis. (medscape.com)
- Conjugative Pili of Plasmids in Escherichia Coli K-12 and Pseudomonas Species. (fishpond.com.au)
- Vesicle production has been reported in other gram-negative pathogens including Pseudomonas aeruginosa ( 9 ), Neisseria gonorrhoeae ( 3 ), Actinobacillus actinomycetemcomitans ( 16 ), Bacteroides fragilis ( 18 ), and Haemophilus influenzae ( 11 ). (asm.org)
- The predominant aerobes were Escherichia coli ( n = 8) and Proteus sp. (asm.org)
- Genes from B. fragilis Bf-2 were cloned on a recombinant plasmid pMT100 which made E. coli AB1157 and uvrA, B, and C mutant strains more resistant to metronidazole, but more sensitive to far uv irradiation under aerobic conditions. (nih.gov)
- and BTF-37-harboring Bacteroides and E. coli strains revealed the presence of pilus-like cell surface structures. (asm.org)
- B. fragilis strains, especially in the United States, are virtually always susceptible to metronidazole, carbapenems, and beta-lactam antibiotics ( 1 ). (cdc.gov)
- Although isolated cases of resistance to single agents have been reported, multidrug-resistant (MDR) B. fragilis strains are exceptionally rare ( 1,2 ). (cdc.gov)
- Here, we studied GA3 T6SSs and show that they antagonize most human gut Bacteroidales strains analyzed, except for B. fragilis strains with the same T6SS locus. (pnas.org)
- Pathogenic Escherichia coli strains are capable of using hemoglobin as an iron source. (rupress.org)
- The proteolytic activity of selected Bacteroides fragilis strains was evaluated by zymography and, after gastrointestinal digestion of gliadin, by high-pressure liquid chromatography/electrospray ionization/tandem mass spectrometry. (asm.org)
- The effects of B. fragilis strains on Caco-2 cell culture permeability and inflammatory response to digested gliadin were determined. (asm.org)
- B. fragilis strains, representing the isolated clones and carrying metalloprotease genes, showed gelatinase activity and exerted the strongest adverse effects on the integrity of the Caco-2 cell monolayer. (asm.org)
- All B. fragilis strains also showed gliadin-hydrolyzing activity, and some of them generated immunogenic peptides that preserved or increased inflammatory cytokine production (tumor necrosis factor alpha) and showed increased ability to permeate through Caco-2 cell cultures. (asm.org)
- These findings suggest that increased abundance of B. fragilis strains with metalloprotease activities could play a role in CD pathogenesis, although further in vivo studies are required to support this hypothesis. (asm.org)
- Plasmid-Specified Iron Uptake by Bacteraemic Strains of Escherichia Coli. (fishpond.com.au)
- including B. fragilis ), and Enterobacter spp. (rxlist.com)
- Ceftriaxone sodium has also been used successfully in a limited number of cases of meningitis and shunt infection caused by Staphylococcus epidermidis and Escherichia coli , however, the efficacy for these organisms in this organ system were studied in fewer than ten infections. (drugs.com)
- The Bacteroides fragilis group consists of species of obligate anaerobic bacteria that inhabit the human gut. (cdc.gov)
- Here we show that the abundant gut species Bacteroides fragilis produce T6SSs that deploy previously undescribed toxins able to antagonize numerous species of human gut Bacteroidales. (pnas.org)
- Because the genes encoding effector and immunity proteins are contained in two variable regions of GA3 loci, GA3 T6SSs of the species B. fragilis are likely the source of numerous novel effector and immunity proteins. (pnas.org)
- The two commonly found species, Escherichia coli and Bacteroides fragilis, together cause DNA damage that could lead to cancer-causing mutations, although it has not yet been shown they do the same in people. (newscientist.com)
- Pathogenic Escherichia coli and Shigella species are responsible for a variety of illnesses, ranging from urinary tract infections to persistent diarrhea. (asm.org)
- Surface or secreted proteases that can release heme from hemoglobin are produced by Vibrio vulnificus , pathogenic Escherichia coli , and Porphyromonas gingivalis ( 32 , 38 , 41 ). (asm.org)
- The plasmid-encoded toxin (Pet) of enteroaggregative Escherichia coli (EAEC) belongs to a family of high-molecular-weight serine protease autotransporters of Enterobacteriaceae (SPATEs) which also includes Pic from EAEC and Shigella flexneri , EspC from enteropathogenic E. coli , EspP from enterohemorrhagic E. coli , Sat from uropathogenic E. coli , Tsh from avian pathogenic E. coli , and SepA from S. flexneri . (asm.org)
- Escherichia coli) and anaerobic bacteria (e.g. (wikipedia.org)
- Horses inoculated with pure cultures of either E. coli or B. fragilis demonstrated mild and self-limiting peritonitis, while those inoculated with a combination of both bacteria demonstrated laboratory findings of higher intensity and duration. (scielo.br)
- Escherichia coli and Bacteroides fragilis are bacteria present in the normal intestinal flora of horses and are responsible for natural peritonitis (Ricketts, 1987). (scielo.br)
- Escherichia coli predominates during the acute phase of the process, whereas in the chronic phase, when abscess formation occurs, the predominance is of anaerobic bacteria, mainly Bacteroides fragilis and enterococci, which act synergistically 1,2 . (scielo.br)
- In vitro studies of Bacteroides and other bacteria have addressed mechanisms of conjugative transfer and some phenotypic outcomes of these DNA acquisitions in the recipient, such as the acquisition of antibiotic resistance. (asm.org)
- Garenoxacin and moxifloxacin demonstrated similar in vitro antimicrobial activity against selected anaerobic gram-positive and gram-negative anaerobic bacteria such as members of the Bacteroides fragilis group. (nih.gov)
- Enterotoxigenic Bacteroides fragilis is the most frequent disease-causing anaerobe in the intestinal tract of humans and livestock and its specific virulence factor is fragilysin, also known as B. fragilis toxin. (rcsb.org)
- Bacteriophage infecting the anaerobe Bacteroides fragilis subsp. (biomedsearch.com)
- Isolation and Characterization of BTF-37: Chromosomal DNA Captured from Bacteroides fragilis That Confers Self-Transferability and Expresses a Pilus-Like Structure in Bacteroides spp. (asm.org)
- We report the isolation and preliminary characterization of BTF-37, a new 52-kb transfer factor isolated from Bacteroides fragilis clinical isolate LV23. (asm.org)
- In B. fragilis, NANase production from the two plasmids was inducible by free N-acetylneuraminic acid or sialic acid-containing substrates, just as in the parental TAL2480 strain. (asm.org)
- In May 2013, an MDR B. fragilis strain was isolated from the bloodstream and intra-abdominal abscesses of a patient who had recently received health care in India. (cdc.gov)
- Our data support that GA3 T6SSs likely allow the producing B. fragilis strain to create a protected niche in the human colon. (pnas.org)
- A local B. fragilis host strain, SP25 (DSM29413), was isolated from a pooled swine feces sample taken from a non-antibiotic farm. (iwaponline.com)
- The reference B. fragilis strain, RYC2056, could detect phages in swine samples but also detected phages in most human sewage and polluted urban canal samples. (iwaponline.com)
- B. fragilis strain SP25 exhibited relatively high resistance to most of the veterinary antimicrobial agents tested. (iwaponline.com)
- In FAP patients the specific B. fragilis strain, called ETBF, produced a toxin that causes colon inflammation. (cnbc.com)
- Based on literature review, calibration of the antibiotic-resistance spectra of Escherichia coli or the bifidobacterial tracking ratio should be investigated locally for potential implementation into the existing monitoring system. (mdpi.com)
- By using an in vitro pharmacodynamic model in duplicate, Escherichia coli and Bacteroides fragilis were exposed to peak concentrations of 8.5 mg of levofloxacin/liter q24h, 32 mg of metronidazole/liter q24h, and 2 mg for moxifloxacin/liter q24h for 24 h. (elsevier.com)
- Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli. (asm.org)
- We have cloned the Bacteroides fragilis TAL2480 neuraminidase (NANase) structural gene, nanH, in Escherichia coli. (asm.org)
- By using deletion analysis and Tn1000 mutagenesis, the NANase structural gene and control region that functions in B. fragilis were localized to a 1.5- to 2.0-kb region of the insert. (asm.org)
- For Bacteroides , although preliminary information on initiation processes is available (one to three gene products are involved depending on the transfer factor) ( 40 , 41 , 43 , 47 , 54 , 55 , 61 ), there are no reports on the existence or nature of a mating apparatus. (asm.org)
- Because no similar protein has been found outside enterotoxigenic B. fragilis, our findings support that fragilysins derived from a mammalian adamalysin/ADAM xenolog that was co-opted by B. fragilis through a rare case of horizontal gene transfer from a eukaryotic cell to a bacterial cell. (rcsb.org)
- Lactamase Gene of Escherichia Coli. (fishpond.com.au)
- The carbapenem-hydrolyzing β-lactamase gene of P. aeruginosa COL-1 was cloned, sequenced, and expressed in Escherichia coli DH10B. (asm.org)
- Cloning of Bacteroides fragilis plasmid genes affecting metronidazole resistance and ultraviolet survival in Escherichia coli. (nih.gov)
- Since reduced metronidazole causes DNA damage, resistance to metronidazole was used as a selection method for the cloning of Bacteroides fragilis genes affecting DNA repair mechanisms in Escherichia coli. (nih.gov)
- Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure. (nih.gov)
- There is little known about the sequences that mediate the initiation of transcription in Bacteroides fragilis, thus transcriptional start sites for 13 new genes were determined and a total of 23 promoter regions upstream of the start sites were aligned and similarities were noted. (nih.gov)
- Bacteroides clones ( n = 274) were isolated, identified, and screened for the presence of the virulence genes ( bft and mpII ) coding for metalloproteases. (asm.org)
- B. fragilis clones carrying virulence genes coding for metalloproteases were more abundant in CD patients than in controls. (asm.org)
- including K. pneumoniae* ), Bacteroides spp. (rxlist.com)
- However, the biochemical properties of recombinant B. fragilis sialidase expressed in a heterologous host remain uncharacterized. (kagawa-u.ac.jp)
- In this study, we examined the enzymatic properties of the 60-kDa sialidase NanH1 of B. fragilis YCH46, which was prepared as a recombinant protein (rNanH1) in Escherichia coli. (kagawa-u.ac.jp)
- The results and methods described in this study will be useful for preparing and characterizing recombinant proteins for other B. fragilis sialidase isoenzymes. (kagawa-u.ac.jp)
- Both blood culture and abdominal fluid culture isolates were identified as B. fragilis . (cdc.gov)
- Traditional fecal indicators, such as total coliforms, fecal coliforms, and Escherichia coli , cannot specifically assess fecal origin. (iwaponline.com)
- We assessed the occurrence and specificity of bacteriophages of Bacteroides fragilis in swine farms for their potential application in microbial source tracking. (iwaponline.com)
- BTF-37 was obtained by the capture of new DNA in the nonmobilizable Bacteroides-Escherichia coli shuttle vector pGAT400ΔBglII using a functional assay. (asm.org)
- Fig. 2) Specimens sent for culture grew E. coli, and no sulfur granules were seen, The patient required three additional debridements of the hip with subsequent cultures positive for Bacteroides fragilis and Cryptococcus asacrolyticus. (healio.com)
- The activities of levofloxacin, metronidazole, moxifloxacin, and levofloxacin plus metronidazole were evaluated against E. coli, B. fragilis, and E. coli plus B. fragilis. (elsevier.com)
- Levofloxacin and moxifloxacin achieved a 3-log killing against E. coli and B. fragilis in all experiments, as did metronidazole against B. fragilis. (elsevier.com)
- The area under the concentration-time curve/MIC ratios for E. coli and B. fragilis were 171.7 and 85.9, respectively, for levofloxacin and 26 and 103.9, respectively, for moxifloxacin. (elsevier.com)
- Levofloxacin plus metronidazole administered once daily exhibited activity similar to that of moxifloxacin against the mixed E. coli and B. fragilis infection. (elsevier.com)
- The loci affecting metronidazole resistance and uv sensitivity were linked and located on a 5-kb DNA fragment which originated from the small 6-kb cryptic plasmid pBFC1 present in B. fragilis Bf-2 cells. (nih.gov)
- NANase was produced from this plasmid both in E. coli and in B. fragilis. (asm.org)
- Dorothee Miiller and Colin Hughes Chromosomal and Plasmid-Mediated Transfer of Clindamycin Resistance in Bacteroides Fragilis. (fishpond.com.au)
- rNanH1 preferentially hydrolyzed the sialyl α2,8 linkage and cleaved sialic acids from mucin and serum proteins (e.g., fetuin and transferrin) but not from α1-acid glycoprotein, which is similar to the previously observed biochemical properties for a native sialidase purified from B. fragilis SBT3182. (kagawa-u.ac.jp)