ERYTHROCYTE size and HEMOGLOBIN content or concentration, usually derived from ERYTHROCYTE COUNT; BLOOD hemoglobin concentration; and HEMATOCRIT. The indices include the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), and the mean corpuscular hemoglobin concentration (MCHC).
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
The semi-permeable outer structure of a red blood cell. It is known as a red cell 'ghost' after HEMOLYSIS.
The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
Transplantation of an individual's own tissue from one site to another site.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Progenitor cells from which all blood cells derive.
Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.
Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.
The privacy of information and its protection against unauthorized disclosure.
The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)
A plant genus of the family POLYGONACEAE that is used as an EDIBLE GRAIN. Although the seeds are used as cereal, the plant is not one of the cereal grasses (POACEAE).
The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.
Macrophages found in the TISSUES, as opposed to those found in the blood (MONOCYTES) or serous cavities (SEROUS MEMBRANE).
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
A subspecialty of internal medicine concerned with morphology, physiology, and pathology of the blood and blood-forming tissues.
Tests used in the analysis of the hemic system.
Individuals licensed to practice medicine.
A medical specialty concerned with the provision of continuing, comprehensive primary health care for the entire family.
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
Chemical, spectroscopic, or microscopic detection of extremely small amounts of blood.
Patterns of practice related to diagnosis and treatment as especially influenced by cost of the service requested and provided.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
Shortened forms of written words or phrases used for brevity.
Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.
Fatty acids which are unsaturated in only one position.
FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activity.
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the food normally. Fortified food includes also food to which various nutrients have been added to compensate for those removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)
Food processed and manufactured for the nutritional health of children in their first year of life.
Iron or iron compounds used in foods or as food. Dietary iron is important in oxygen transport and the synthesis of the iron-porphyrin proteins hemoglobin, myoglobin, cytochromes, and cytochrome oxidase. Insufficient amounts of dietary iron can lead to iron-deficiency anemia.
A species of gram-negative bacteria in the genus CHRONOBACTER, found in the environment and in foods.
Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.
Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.
Drugs that act on blood and blood-forming organs and those that affect the hemostatic system.
Lesion on the surface of the skin of the foot, usually accompanied by inflammation. The lesion may become infected or necrotic and is frequently associated with diabetes or leprosy.
Increased numbers of platelets in the peripheral blood. (Dorland, 27th ed)

Iron supplemented formula milk related to reduction in psychomotor decline in infants from inner city areas: randomised study. (1/460)

OBJECTIVE: To compare the effect of unmodified cows' milk and iron supplemented formula milk on psychomotor development in infants from inner city areas when used as the main milk source. DESIGN: Double blind, randomised intervention trial. SETTING: Birmingham health centre. SUBJECTS: 100 infants, mean age 7.8 months (range 5.7 to 8.6 months), whose mothers had already elected to use unmodified cows' milk as their infant's milk source. INTERVENTION: Changing to an iron supplemented formula milk from enrolment to 18 months of age, or continuing with unmodified cows' milk. MAIN OUTCOME MEASURES: Developmental assessments using Griffiths scales at enrolment and at 18 and 24 months. RESULTS: 85 participants completed the trial. There were no significant differences in haemoglobin concentration between the two groups at enrolment, but by 18 months of age 33% of the unmodified cows' milk group, but only 2% of the iron supplemented group, were anaemic (P<0.001). The experimental groups had Griffiths general quotient scores that were not significantly different at enrolment, but the scores in both groups declined during the study. By 24 months the decrease in the mean scores in the unmodified cows' milk group was 14.7 whereas the decrease in the mean scores in the iron supplemented group was 9.3 (P<0.02, 95% confidence interval 0.4 to 10.4). Mean subquotient scores were considerably lower in the unmodified cows' milk group at 24 months; significantly so for personal and social scores (P<0.02, 1.2 to 16.8 [corrected]). CONCLUSION: Replacing unmodified cows' milk with an iron supplemented formula milk up to 18 months of age in infants from inner city areas prevents iron deficiency anaemia and reduces the decline in psychomotor development seen in such infants from the second half of the first year.  (+info)

Stomatocytosis is absent in "stomatin"-deficient murine red blood cells. (2/460)

To examine the relationship between erythrocyte membrane protein 7. 2b deficiency and the hemolytic anemia of human hereditary stomatocytosis, we created 7.2b knock-out mice by standard gene targeting approaches. Immunoblots showed that homozygous knock-out mice completely lacked erythrocyte protein 7.2b. Despite the absence of protein 7.2b, there was no hemolytic anemia and mouse red blood cells (RBCs) were normal in morphology, cell indices, hydration status, monovalent cation content, and ability to translocate lipids. The absence of the phenotype of hereditary stomatocytosis implies that protein 7.2b deficiency plays no direct role in the etiology of this disorder and casts doubt on the previously proposed role of this protein as a mediator of cation transport in RBC.  (+info)

Evidence that microdeletions in the alpha globin gene protect against the development of sickle cell glomerulopathy in humans. (3/460)

There is a large variability in the severity of the clinical manifestations of sickle cell anemia (SSA), including renal involvement. Haplotypes in the beta-globin gene cluster associated with the geographical origin of the sickle mutation, as well as microdeletions in the alpha-globin genes, could provide an epigenetic influence on the heterogeneous outcome in SSA. It has been determined that the cause of progressive renal insufficiency in SSA is a glomerulopathy, clinically detected by the presence of macroalbuminuria (albumin excretion rate >300 mg/g creatinine). To investigate the role of the alpha-globin gene microdeletion and beta-globin gene cluster haplotypes on the degree of glomerular involvement, 76 adult SSA patients (hemoglobin SS) were studied to determine the relationship between these genetic markers and the development of sickle cell glomerulopathy. Macroalbuminuria was present in 22 (29%) of 76 adult SSA patients. The coinheritance of microdeletions in one or two of the four alpha-globin genes (alpha-thalassemia) was associated with a lower prevalence of macroalbuminuria (13%) versus patients with intact alpha-globin genes (40%, P = 0.01). By contrast, there was no association between albuminuria and beta-globin gene haplotypes (Central African Republic [CAR] versus non-CAR haplotypes). Patients with alpha-globin gene microdeletions had lower mean corpuscular volumes and mean corpuscular hemoglobin concentration than patients with all four alpha genes (86+/-2 versus 99+/-3 fl, and 33.9+/-0.2 versus 34.9+/-0.2%, respectively, P<0.05). There were no such hematologic differences between CAR and non-CAR beta-globin haplotypes. There were no differences in duration of disease (age), hemoglobin levels, reticulocyte index, and lactate dehydrogenase levels between those with and without glomerulopathy, but the mean arterial pressure was higher (87+/-1 mm Hg) in patients with intact alpha gene locus versus those with microdeletions (80+/-2 mm Hg, P<0.05). It is concluded that the coinheritance of microdeletions in the alpha-globin gene locus in SSA patients confers "renoprotection" by mechanisms not related to the degree of anemia or the severity of hemolysis, but could be related to a reduced mean corpuscular volume or to a lower erythrocyte hemoglobin concentration.  (+info)

The contribution of alpha+-thalassaemia to anaemia in a Nigerian population exposed to intense malaria transmission. (4/460)

The proportion to which alpha-thalassaemia contributes to anaemia in Africa is not well recognized. In an area of intense malaria transmission in South-West Nigeria, haematological parameters of alpha-thalassaemia were examined in 494 children and 119 adults. The -alpha3.7 type of alpha+-thalassaemia was observed at a gene frequency of 0.27. Nine and 36.5% of individuals were homozygous and heterozygous, respectively. P.falciparum-infection was present in 78% of children and in 39% of adults. The alpha-globin genotypes did not correlate with the prevalence of P. falciparum-infection. alpha+-thalassaemic individuals had significantly lower mean values of haemoglobin, mean corpuscular volume, and mean corpuscular haemoglobin than non-thalassaemic subjects. Anaemia was seen in 54. 7% of children with a normal alpha-globin genotype, in 69.9% of heterozygous (odds ratio: 1.99, 95% confidence interval: 1.32-3.00, P = 0.001), and in 88.4% of homozygous alpha+-thalassaemic children (odds ratio: 7.72, 95% confidence interval: 2.85-20.90, P = 0.0001). The findings show that alpha+-thalassaemia contributes essentially to mild anaemia, microcytosis, and hypochromia in Nigeria.  (+info)

Nisoldipine improves the impaired erythrocyte deformability correlating with elevated intracellular free calcium-ion concentration and poor glycaemic control in NIDDM. (5/460)

AIMS: To explore the mechanisms underlying the impaired erythrocyte deformability (RBC-df) in diabetic patients, the relationship between erythrocyte intracellular free calcium-ion concentration ([Ca2+]i) and RBC-df, and the effects of Ca2+-channel blocker on [Ca2+]i and RBC-df were evaluated. METHODS: Forty-eight patients with NIDDM and 24 control subjects were enrolled in this study. [Ca2+]i was determined using fura-2, and RBC-df by filtration method expressed as Deformability Index (DI). Erythrocytes were treated with nisoldipine to evaluate the effects of a Ca2+-channel blocker. RESULTS: [Ca2+]i was significantly higher (82.6 (78.0-87.2) vs 76.6 (74.3-81.2) nmol lRBC-1, P<0.001), and DI was significantly lower (0. 14 (0.09-0.28) vs 0.22 (0.16-0.28), P<0.01) in NIDDM than in controls. There was a significant correlation between HbA1c and [Ca2+]i (r=0.38, P<0.01), between HbA1c and DI (r=-0.51, P<0.01), and between [Ca2+]i and DI (r=-0.42, P<0.01). Stepwise multiple regression analysis revealed HbA1c and [Ca2+]i as independent determinants for the impaired RBC-df. Nisoldipine treatment in vitro significantly decreased [Ca2+]i, and significantly improved RBC-df. CONCLUSIONS: These data indicate that the impaired RBC-df in NIDDM may at least partly be attributed to the elevated [Ca2+]i and poor glycaemic control. In addition, favorable effects of a Ca2+-channel blocker on both [Ca2+]i and RBC-df have been demonstrated.  (+info)

Red cell indices and discriminant functions in the detection of beta-thalassaemia trait in a population with high prevalence of iron deficiency anaemia. (6/460)

Red cell indices and discriminant functions were studied in 463 heterozygous beta-thalassaemics (337 without iron deficiency, 126 with iron deficiency) and 195 patients of iron deficiency anaemia (IDA) to ascertain their utility in the detection of betathalassaemia trait (BTT). Majority of traits in both groups had an elevated RBC count (> or = 5.0 x 10(12)/L). The counts were significantly higher than of patients with IDA, only 4.6% of whom had this degree of erythrocytosis. Mean Hb concentration was significantly higher in traits as compared to iron deficient subjects (p < 0.0001). Mean MCV and MCH were significantly (p < 0.0001) lower in traits more so in those with ID as compared to patients of IDA. MCV < 80 fl and MCH < 27 pg were found to be sensitive markers in the detection of traits even in the presence of ID. Of the four discriminant functions studied MCSQ was found to be most sensitive in detection of BTT and it identified 97.9% traits. DF of England and Fraser was most specific for BTT being < 8.4 in only 6.2% patients with IDA. Detection of erythrocytosis especially in the presence of mild anaemia and calculation of discriminant functions derived from red cell indices were found to play an important role in screening for BTT even in the presence of ID and helped identify those patients who required further laboratory evaluation.  (+info)

Factors determining the percentage of hypochromic red blood cells in hemodialysis patients. (7/460)

Factors determining the percentage of hypochromic red blood cells determines iron status in hemodialysis patients. BACKGROUND: Determination of the percentage of hypochromic red blood cells (RBC; %HYPO) has been advocated as a sensitive index of functional iron deficiency during erythropoietin (EPO) therapy in hemodialyzed patients. METHODS: The significance of %HYPO in chronic renal failure was evaluated in 64 chronically hemodialyzed patients. The linear correlation was determined between %HYPO and 13 variables, including age, sex, weight, C-reactive protein (CRP), ferritin, transferrin (Tf), Tf saturation, soluble Tf receptor (sTfR), serum iron (SI), urea, parathormone, dialysis dose (Kt/V), dose of EPO administered (EPO), and absolute reticulocyte count. Multiple regression analyses were then performed to select the parameters that jointly provide the best prediction of %HYPO. RESULTS: Univariate analysis showed significant correlations between %HYPO and iron parameters (sTfR, Tf saturation, SI, and ferritin, in decreasing order), EPO, reticulocyte count, and CRP. Multivariate analysis yielded an equation showing that the variation of %HYPO is essentially associated with the combined changes in sTfR, CRP, and EPO dosage. CONCLUSIONS: %HYPO is a meaningful and inexpensive parameter that reflects the integrated effects of iron stores, inflammation, and erythropoietic stimulation on iron availability in hemodialyzed patients. Among iron exchange parameters, sTfR is the best predictor of %HYPO, followed by Tf saturation, SI, and ferritin.  (+info)

Influence of age, alcohol consumption and abstinence on the sensitivity of carbohydrate-deficient transferrin, gamma-glutamyltransferase and mean corpuscular volume. (8/460)

Duration of abstinence before blood test, alcohol consumption and age was examined in 177 male alcohol-dependent patients as factors influencing serum carbohydrate-deficient transferrin (CDT), serum gamma-glutamyltransferase (GGT) and mean corpuscular volume (MCV). The strongest influence on all markers was the factor 'duration of abstinence before blood test'. In patients who had been abstinent for >4 days before the blood test, the markers had low sensitivities (GGT, 33%; CDT, 14%; MCV, 42%), whereas in patients with < or = 4 days of abstinence the markers had reasonably good sensitivities (GGT, 72%; CDT, 56%; MCV, 48%). GGT was more sensitive than CDT (P < 0.05) and MCV (P < 0.001). The combined use of CDT and GGT had sensitivity of over 90%. Mean alcohol consumption in the 30 days prior to the blood test had a significant effect on CDT and GGT, but not on MCV. Age did not have a clear effect on CDT and GGT. For MCV, a significant and linear increase with age was shown. We conclude that GGT is the most sensitive of these three markers. Using GGT and CDT combined, sensitivity can be enhanced to over 90%. The period of abstinence before the blood test has a strong influence on CDT and GGT. If a longer period of abstinence is suspected, MCV should also be measured, in order to detect evidence of earlier heavy drinking.  (+info)

Definition of mean corpuscular hemoglobin concentration (MCHC) in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is mean corpuscular hemoglobin concentration (MCHC)? Meaning of mean corpuscular hemoglobin concentration (MCHC) as a finance term. What does mean corpuscular hemoglobin concentration (MCHC) mean in finance?
Background: Red blood cell distribution width (RDW) is a biomarker for cardiovascular disease(CVD). RDW is associated with sedentary behavior (SB) and physical activity (PA) in adults.To date, no study has evaluated this association in children. The purpose of this study was to evaluate the association between RDW and SB and PA levels of children and adolescents.Methods: This observational study included data from participants aged 12-20 years in the 2003-2006 National Health and Nutrition Examination Survey (NHANES). SB and PA were measured using accelerometers. Activity levels were classified into intensity categories. Sex specific multivariable regression analyses (adjusted for covariates) were used to explore the associations between SB, PA and RDW. Results: The study included 2143 children and adolescents (1080 boys and 1063 girls). In the fully adjusted regression model for boys, SB was positively associated with RDW (β =0.116,P=0.004) while moderate PA was negatively associated with RDW (β =-0
1.98% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased red blood cell distribution width (43/2177) 1.30% females (28/2150) 1.79% males (39/2173) ...
Significance of low red cell distribution width (low RDW) and high red cell distribution width (high RDW) levels on blood tests: Easy to understand entry.
BackgroundRed blood cell distribution width (RDW), an automated measure of red blood cell size heterogeneity (eg, anisocytosis) that is largely overlooked, is a
Objective: To examine the association between elevated levels of red cell distribution width (RDW) and cardiovascular risk factors (CVRF) and metabolic syndrome (MS) in HIV-patients. Methods: Cross-sectional study including all asymptomatic HIV-outpatients under follow-up during 2007. Patients completed a questionnaire about CVRF, underwent a physical examination, and an 8-hour fasting blood analysis. Elevated RDW was defined as ≥75th percentile. Patients with and without an elevated RDW were compared. Results: 666 patients (79.3% men) were included: mean age 44.7 years, mean CD4 506/mm3 and 87.5% on antiretroviral therapy (85.3% with undetectable viral load). Mean RDW was 13.7% (range: 7.7% - 33.6%; 75th percentile, 14.1%). The prevalence per quartile of MS was 15.7%, 9.3%, 18.8% and 16.6% and of patients with CVRF > 20% was 8.4%, 4.0%, 4.4%, and 6.4%, respectively (p > 0.05); 23.4% of the patients had an elevated RDW (>14.1%). The top percentile of RDW was associated with AIDS (OR 1.6; 95%
Background: Higher red cell distribution width (RDW) is an independent predictor of greater morbidity and mortality in the general population and in myocardial infarction, coronary disease, heart failure (HF), and other patient sets. We aimed to study the predictive ability of RDW and change in RDW (ΔRDW) for length of stay (LOS) and 30-day outcomes for HF exacerbations.. Methods: Electronic query of Intermountain Healthcare medical records identified patients (N=6,414) with a primary diagnosis of HF who were discharged in 2004-2013, had RDW measured within 24 hours after admission, and had RDW tested at least once more during the same hospitalization. ΔRDW was calculated as the last RDW within 24 hours prior to discharge minus the first RDW. All patients were aged 65 years or older and were discharged alive and not to hospice.. Results: Average age was 78.9±7.8 years and 50.2% were female. Median LOS by ΔRDW quartiles was Q1: 4.1, Q2: 3.4, Q3: 3.6, and Q4: 4.7 days (p-trend,0.001), and by ...
Aim: Although the relationship between red cell distribution width (RDW) and hypertension has been well documented, there is an absence of data on the association between RDW and preeclampsia. In the present study, we have aimed to investigate the correlation of RDW with preeclampsia and its severity. Methods: The study population consisted of 52 (35 mild and 17 severe) patients with preeclampsia and 50 control pregnancy patients. For the entire study population, baseline RDW was measured using an automatic blood counter. Results: Although there were no significant differences between the preeclampsia group and the control group in terms of hemoglobin and platelet counts, the RDW (14.1 +/- 1.1 vs 16.9 +/- 1.7, P
Red cell distribution width (RDW) and the neutrophil/lymphocyte ratio (NLR) are predictors of cardiovascular risk that have been shown to correlate with impaired reperfusion and increased morbidity and mortality in patients with an ST-segment elevati
Aims: We aimed to observe the correlation between Red Cell Distribution Width (RDW) and acute attack of Chronic Obstructive Pulmonary Disease (COPD). ..
The Comparison of Apache Ii Scores with Neutrophil Lymphocyte Ratio and Red Cell Distribution Width for the Prediction of Prognosis of Patients with Acute Pancreatitis, Murat Orak,
It is unclear whether red cell distribution width is a risk factor for early death or a byproduct of biological and metabolic imbalances.
Book Mean Corpuscular Haemoglobin Concentration (MCHC)-Calculated Lab Test appointment online at Home. View details of Mean Corpuscular Haemoglobin Concentration (MCHC)-Calculated: procedure, normal range and Get the reports Online
Book Mean Corpuscular Haemoglobin Concentration (MCHC)-Calculated Lab Test appointment online at Home. View details of Mean Corpuscular Haemoglobin Concentration (MCHC)-Calculated: procedure, normal range and Get the reports Online
RESULTS: Three hundred and ninety patients were included. The ICU mortality rate was 56% (N.=220) and 64% of patients (N.=251) had an unfavorable 3-month neurological outcome. The median RDW on the day of admission was 14% (13.0-15.2%) and remained stable over the observation period. Two hundred and forty-five patients (63%) had a high RDW (>13.4%) on admission. In multivariable logistic regression analysis, older age, absence of bystander cardiopulmonary resuscitation (CPR), a non-cardiac etiology of the arrest, a non-shockable initial rhythm, high adrenaline dose during CPR and high admission RDW levels were independently associated with an unfavorable outcome at 3 months ...
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Download Free Full-Text of an article THE EFFECTS OF AEROBIC EXERCISE ON ERYTHROCYTE INDICES IN CANCER PATIENTS AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION
The mean corpuscular haemoglobin concentration refers to the average concentration of haemoglobin within red blood cells, and confers whether a cell is normochromic, hyperchromic or hypochromic.
Patient: Hi all I was hoping for some help interpreting some result blood results please?Haemoglobin concentration 140 (115.0-160.0)Total white blood count 6.8 (4.0-12.0)Red blood cell count. 4.18 ( 4.2-5.4) below rangeHaematocrit. 0.4 (0.37-0.47)Mean cell volume. 95.7 (78.0-100.0)Mean cell haemoglobin. 33.5 (27.0- 32.0) high in rangeMean cell haemoglobin concentration 350.0 (310.0-350.0)Platelet count. 180 ( 140-450)Red blood cell distribution width 11.6 % ( 11.0- 16.0)Serum vit B12. 604 (187.0-883.0)Serum folate. 11.3 (3.1- 20.5)Serum ferritin. 20 (10-204)Could I have anemia? I am feeling very weak, aching limbs, headaches, sores in my mouth, always pale, covered in bruises and cold hands and feet etc.I was going to take some iron even though my dr was not concerned but dont want to take anything I shouldnt and end up feeling worse. I have been feeling ill since the birth of my child 3 years ago.If anyone could help me it would be much appreciated.Thanks ...
Definition of mean corpuscular hemoglobin (MCH) in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is mean corpuscular hemoglobin (MCH)? Meaning of mean corpuscular hemoglobin (MCH) as a finance term. What does mean corpuscular hemoglobin (MCH) mean in finance?
This mean corpuscular hemoglobin concentration (MCHC) calculator determines the concentration of Hb in the erythrocytes as MCHC is one of the RBC indices.
title:Mean Platelet Volume and Red Cell Distribution Width in Hepatosteatosis. Author:Gulali Aktas, Aytekin Alcelik, Buket Kin Tekce, Haluk Savli, Ummugul Uyeturk, Mevlut Kurt, Vildan Tekelioglu, Yusuf Yuce. Keywords:Red Cell Distribution Width, Mean Platelet Volume, Hepatosteatosis, Inflammation. Type:Original Article. Abstract:Introduction: Non-alcoholic fatty liver disease (NAFLD) effects about 30% of the population in developed regions of the and is considered hepatic manifestation of metabolic syndrome. Studies in literature found association between hepatosteatosis and mean platelet volume (MPV), an indicator of platelet function. Furthermore, authors suggest thatred cell distribution width (RDW) should be an inflammatory marker in certain conditions. Objective: We aimed in this study to compare RDW and MPV values of the patients with hepatosteatosis to normal population. Methods: Fifty-three patients with NAFLD admitted to our clinic and 52 healthy controls enrolled to this retrospective ...
Body mass index (BMI), the prevalent indicator of obesity, is not easily grasped by patients nor physicians. Waist circumference (WC) is correlated to obesity, is better understood and has a stronger relationship to the metabolic syndrome. We compiled WC, complete blood count (CBC) parameters as well as other pertinent data of 6766 25-55-year-old US volunteers sampled in the US National Health and Nutrition Examination Survey, in the years 2005-2010. To determine reference intervals of typical US patients visiting their clinician, we used minimal exclusion criteria. We compiled hemoglobin, red blood cell count, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration, mean cell hemoglobin (MCH), red cell distribution width (RDW), platelet count, mean platelet volume, and counts of white blood cells (WBC), neutrophils, lymphocytes, monocytes, eosinophils, and basophils. In addition, we also compiled serum C reactive protein and serum iron. The three major US races were ...
The third step in working up an anemia is to assess red cell size (i.e., volume - the mean corpuscular volume [MCV], normal range ca. 80-100 femtoliters) and size distribution (the red blood cell distribution width [RDW], a measure of circulating red cell size variability, attempts to quantitate the older descriptor for size heterogeneity:anisocytosis). An abnormal MCV can be very helpful in narrowing the likely source of anemia. Conversely, a normal MCV cannot be taken to rule out those sources typically associated with microcytosis (MCV, 80) or macrocytosis (MCV,100).. Microcytic anemias (MCV , 80) are invariably due to defects in hemoglobin production. This occurs because of iron deficiency (by far the most common), thalassemia, sideroblastic anemias, or, uncommonly, the anemia of chronic inflammation. Thalassemia trait usually presents with profound microcytosis and mild to moderate anemia (MCV, 70, Hct, 30), in iron deficiency the MCV rarely falls below 80 until the anemia is significant ...
International Journal of Chronic Diseases is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of chronic diseases.
BULGULAR: al maya 55 i erkek, 48 i kad n olmak zere toplam 103 hasta al nd . Hastalar n ya ortalamas 64.4 14 (SS), mortalite oran ise %50.5 idi. Mortalite olan hastalar n yo un bak ma yat an ndaki ortalama EDG (EDG1) de eri ve APACHE-II skorlar mortalite olmayan hastalardan daha y ksek idi. Lojistik regresyon analizinde sadece APACHE-II skoru ve EDG1 de erlerinin istatistiksel olarak mortaliteyi etkiledi i saptand . ROC analizinde e ri alt nda kalan alan EDG1 i in 0.867 (G ven aral : 0.791 0.942) olarak, APACHE-II i in ise 0.943 (G ven aral : %95, 0.902 0.984) olarak saptand ...
|p|B ackground: Red blood cell distribution width (RDW) that describes red blood cell volume heterogeneity is a common laboratory test. Our aim was to focus on th e association between RDW and a c ute pancreatitis associated lung injury (APALI). Methodology: A total of 152 acute pancreatitis (AP) patients who conformed to the criteria w ere included in this study. The demographic data, medical histories and laboratory measures was obtained from each patient on admission, further, the medical histories and biological data were analyzed, retrospectively. Results: Increased RDW at admission was observed in patients with APALI compared with the non-APALI groups. Our results exhibited that RDW was an independent risk factor for APALI after adjusting leukocyte, neutrophil percentage, random blood glucose (RBG), total bilirubin (TB) and total bile acid(TBA)(Crude model) (OR=2.671;CI 95% 1.145-6.230; P=0.023), further adjustment based on Crude model for sex and age did not attenuate the significantly high
All patients visit at outpatient department before the launch of the study, and 3 and 9 months thereafter. Clinical examination is done by 4 physicians. During the 42-week study period, laboratory tests are conducted on samples collected before treatment, at 20 weeks, and at 42 weeks. The tests include a fungal culture, KOH staining of the toenail sample, and blood tests. Cultures and KOH microscopy are performed in an independent, specialised mycology laboratory with standard techniques (Medix Laboratories Ltd., Helsinki, Finland). The blood tests measure plasma γ-glutamyl transferase levels (also at 2 weeks); plasma creatinine levels; the total number of white blood cells, including neutrophils, monocytes, basophils, lymphocytes, and eosinophils; the total number of red blood cells, including erythrocytes and haematocrit; erythrocyte indices, including the mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, and haemoglobin level; and the total ...
Red blood cell distribution width (RDW) is a hematological parameter usually measured with every complete blood count. Its place in daily practice is mainly in the differential diagnosis of anemia, but nowadays, researchers are focused on different approaches for the erythrocytes changes in function and morphology.. Sepsis and its most advanced form, septic shock, induces profound disturbances into organ systems function and morphology. The red blood cells physiology and structure are directly and indirectly altered by these im balances produced in sepsis. RDW was studied in many diseases, like acute heart failure, acute stroke, inflammatory bowel diseases, chronic lung diseases and cancer, but also in sepsis. Its changes are seen to be mainly associated with prognosis. Higher values of RDW are correlated with mortality and severity of illnes in septic and all-cause critically ill patients. RDW was studied also as an independent variable in different predictive scores and some studies suggest ...
Treat iron deficiency in a menstruating woman. The most appropriate treatment is oral ferrous sulfate. Iron deficiency can result from blood loss or malabsorption in addition to increased iron use. Women of reproductive age may lose enough iron through normal menstrual blood loss to become iron deficient in the absence of uterine or gastrointestinal disease. Patients with mild iron deficiency may note fatigue, lack of sense of well-being, irritability, decreased exercise tolerance, and headaches before symptoms of overt anemia occur. This patient has signs and symptoms of iron deficiency, likely secondary to menstrual blood loss. The peripheral blood smear in patients with iron deficiency is remarkable for microcytic, hypochromic erythrocytes, with marked anisopoikilocytosis (that is, abnormalities in erythrocyte size and shape). The variation in the size of erythrocytes is quantified in the red blood cell distribution width (RDW) measurement. An increased RDW is most often associated with a ...
Supplementary MaterialsS1 Checklist: PRISMA 2009 checklist. belonged to Group A, 9 research belonged to Group B and 17 studies belonged to Group C. Among these included studies, RDW was assessed as a continuous variable (per 1% increase) in 16 studies, like a binary variable in CTSD 8 studies, and as a categorical variable in 8 studies. In addition, AUCs (area under the receiver operating characteristic curve) of RDW for predicting mortality were reported in 25 studies. All studies were published between 2011C2015. The qualities of included 32 studies were moderate or high. Conclusion The present systematic review indicates the increased RDW is definitely significantly associated with a higher mortality rate in an non-cardiovascular emergency. The low cost and readily accessible of this laboratory variable may strengthen its usefulness in daily practice in the future. Introduction Red blood cell distribution width (RDW) is a measure of erythrocyte size variability and calculated as the (standard ...
Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed to establish a new model combing the inflammatory markers including neutrophil/lymphocyte ratio (NLR) and red blood cell distribution width (RDW) with several hematological testing indicators to assess the prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). A derivation cohort with 421 patients and a validation cohort with 156 patients were recruited from three hospitals. Retrospectively collecting their clinical data and laboratory testing indicators. Medcalc-15.10 software was employed for data analyses. Multivariate analysis indicated that RDW, NLR, INR, TBIL and Cr were risk factors for 90-day mortality in patients with HBV-ACLF. The risk assessment model is COXRNTIC = 0.053 × RDW + 0.027 × NLR + 0.003 × TBIL+ 0.317 × INR + 0.003 × Cr (RNTIC) with a cut-off value of 3.08 (sensitivity: 77.89%, specificity: 86.04%). The area under the
1. Change in reporting of adverse events - safety reporting timelines was changed from within 1 working day to within 24 hours for serious adverse events and adverse events of special interest (AESI) with immediate notification. - Addition of pregnancy of male subjects partner as an AESI with immediate notification. 2. Clarification for some safety laboratory parameters - Red blood cell distribution width and reticulocyte count added as hematology laboratory parameters. - Reticulocyte count no longer assessed reflexively but rather systematically on all study samples. 3. Precision added in the definition of the investigational medicinal product - ezetimibe capsule. 4. Highlighted the need for an effective method of contraception in women of childbearing potential throughout the study treatment ...
Red blood cell distribution width (RDW) is a measurement of variability in circulating erythrocytes size, and has recently been shown to correlate with prognosis in a variety of human diseases, including acute and chronic heart failure.To determine if RDW differs between healthy controls, cats with hypertrophic cardiomyopathy (HCM) without congestive heart failure (CHF) and cats with HCM and CHF ...
Red blood cell distribution width (RDW) is a measurement of variability in circulating erythrocytes size, and has recently been shown to correlate with prognosis in a variety of human diseases, including acute and chronic heart failure.To determine if RDW differs between healthy controls, cats with hypertrophic cardiomyopathy (HCM) without congestive heart failure (CHF) and cats with HCM and CHF ...
The receiver-operating characteristic (ROC) curve analysis for red blood cell distribution width in predicting left atrial spontaneous echo contrast. RDW |13
Looking for online definition of mean corpuscular haemoglobin in the Medical Dictionary? mean corpuscular haemoglobin explanation free. What is mean corpuscular haemoglobin? Meaning of mean corpuscular haemoglobin medical term. What does mean corpuscular haemoglobin mean?
A 10-year-old male child came to our out-patient department (OPD) for evaluation of refractory anemia. He had received adequate dietary and oral iron supplementation but still required multiple blood transfusions. He had no anorexia, nausea, vomiting, diarrhea, abdominal cramps or bleeding from any site. There was no family history of blood transfusions. Laboratory investigations showed hemoglobin of 6.4 gm/dl, total leucocyte count 7600 cells/cumm, erythrocyte sedimentation rate (ESR) 18 mm/hr at end of 1 hour, packed cell volume 22%, mean corpuscular volume 54.1fL, mean corpuscular hemoglobin concentration (MCHC) 25.4gm/dL, Red blood cell distribution width (RDW) 17.2%, reticulocyte count 1.13%, serum ferritin 2.6ng/dL, serum iron 15ug/dL and Total Iron Binding Capacity (TIBC) 570 mcg/dL suggestive of iron deficiency anemia (IDA). Peripheral film showed microcytic hypochromic anemia. Hemoglobin electrophoresis and thyroid function tests were normal. Routine stool examination was normal and ...
A 10-year-old male child came to our out-patient department (OPD) for evaluation of refractory anemia. He had received adequate dietary and oral iron supplementation but still required multiple blood transfusions. He had no anorexia, nausea, vomiting, diarrhea, abdominal cramps or bleeding from any site. There was no family history of blood transfusions. Laboratory investigations showed hemoglobin of 6.4 gm/dl, total leucocyte count 7600 cells/cumm, erythrocyte sedimentation rate (ESR) 18 mm/hr at end of 1 hour, packed cell volume 22%, mean corpuscular volume 54.1fL, mean corpuscular hemoglobin concentration (MCHC) 25.4gm/dL, Red blood cell distribution width (RDW) 17.2%, reticulocyte count 1.13%, serum ferritin 2.6ng/dL, serum iron 15ug/dL and Total Iron Binding Capacity (TIBC) 570 mcg/dL suggestive of iron deficiency anemia (IDA). Peripheral film showed microcytic hypochromic anemia. Hemoglobin electrophoresis and thyroid function tests were normal. Routine stool examination was normal and ...
Definition of mean corpuscular hemoglobin concentration. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
TY - JOUR. T1 - Correlation of Red Blood Cell Acetylcholinesterase Enzyme Activity with Various RBC Indices. AU - Gupta, Shalvika. AU - Belle, Vijetha Shenoy. AU - Kumbarakeri Rajashekhar, Ramya. AU - Jogi, Sushma. AU - Prabhu, RV Krishnananda. PY - 2018/9/4. Y1 - 2018/9/4. N2 - Cholinesterases belongs to class hydrolases. There are two types acetylcholinesterase and butyryl cholinesterase. Acetylcholinesterase present in nerve endings and also in the RBC membrane. It helps to maintain the shape and size of RBCs. Any change in shape and size of RBCs may affect the activity of Acetylcholinesterase. Thus this study aimed to estimate RBCs Acetylcholinesterase enzyme activity in various types of anemias and correlate the RBCs Acetylcholinesterase enzyme activity with various hematological indices such as Erythrocyte Sedimentation Rate (ESR), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Mean Corpuscular Volume (MCV), Red cell Distribution Width (RDW) etc. After ...
Correlation analysis between the hematological parameters mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV) for thalassemia screening in large population was discussed. A total of 4920 peripheral blood samples of reproductive age persons were collected from Guangdong province of China. The hematological parameters MCH and MCV values of samples were first measured, and then the DNA analyses for thalassemia were conducted. All samples were composed by 4463 non-thalassemia and 457 thalassemia, and among 457 thalassemia samples, 311 were α-thalassemia, 133 were β-thalassemia, and 13 were α & β-thalassemia. In accordance with non-thalassemia, thalassemia, α-thalassemia, β-thalassemia, α & β-thalassemia and the entire group itself, a total of six sample groups were divided. The corresponding correlation coefficients between the measured MCH and MCV values for the six sample groups were 0.880, 0.968, 0.966, 0.962, 0.980 and 0.965 respectively. For the thalassemia carriers, highly
The essential features of X-linked sideroblastic anemia include the following: (1) a hypochromic microcytic anemia and 2 discrete populations of red blood cells, one microcytic and the other normocytic; (2) marrow ringed sideroblasts, particularly prominent in the late erythroid precursors; (3) a variable hematologic response to pharmacologic doses of pyridoxine; and (4) systemic iron overload secondary to chronic ineffective erythropoiesis. The age of clinical onset of the disorder can vary from in utero to the ninth decade. Whereas males are preferentially affected, females may present with clinically severe anemia. More commonly, female carriers of the disease have an increased red blood cell distribution width and sometimes erythrocyte dimorphism ({18:Fleming, 2002 ...
Red blood cell indices are blood tests that provide information about the hemoglobin content and size of red blood cells. Abnormal values indicate the presence of anemia and which type of anemia it is. Mean corpuscular volume (MCV) is the average volume of a red blood cell and is calculated by dividing the hematocrit (Hct) by the red blood cell count. M C V = H c t R B C {\displaystyle MCV={\frac {Hct}{RBC}}} Normal range: 80-100 fL Mean corpuscular hemoglobin (MCH) is the average amount of hemoglobin (Hb) per red blood cell and is calculated by dividing the hemoglobin by the red blood cell count. M C H = H b R B C {\displaystyle MCH={\frac {Hb}{RBC}}} Normal range: 27-31 pg/cell Mean corpuscular hemoglobin concentration (MCHC) is the average concentration of hemoglobin per unit volume of red blood cells and is calculated by dividing the hemoglobin by the hematocrit. M C H C = H b H c t {\displaystyle MCHC={\frac {Hb}{Hct}}} Normal range: 32-36 g/dL MedlinePlus Medical Encyclopedia: RBC indices ...
Study aim: To assess the prevalence of iron deficiency in competitive male athletes.Material and methods: In total, 90 elite athletes practicing judo, rowing, pentathlon, volleyball, kayaking and biathlon, aged 16-33 years, were studied. Blood morphology indices: haemoglobin concentration (Hb), hematocrit (Hct), red blood cell count (RBC), leucocyte count (WBC), mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were determined. The concentrations of ferritin, soluble transferrin receptor (sTfR) and iron, as well as total iron binding capacity (TIBC), were determined in serum. Additionally, erythropoietin (EPO) was assayed in subjects with elevated sTfR levels.Results: In no case iron-deficiency anaemia was found, but in 43% of subjects iron deficiency was detected. This included first stage of iron deficiency (iron depletion; ID) in 13% of subjects (ferritin ,20 μg/L), and iron-deficient erythropoiesis (IDE) in 30% of ...
Everything you need to know about mean cell haemoglobin and find out which of our blood tests check mean cell haemoglobin levels.
This study aims to assess how mean corpuscular volume (MCV), red cell distribution width (RDW), and thiol-disulphide homeostasis are altered in psoriasis patients. This is a cross-sectional review of 76 healthy volunteers and 87 psoriasis patients who were consecutively admitted to the department of dermatology. Psoriasis patients and healthy controls were statistically similar with respect to age, sex, body mass index, blood pressures, and disease duration ( p>0.05 for all). When compared to healthy controls, psoriasis patients had significantly higher MCV, RDW, C-reactive protein (CRP), disulphide, disulphide/native thiol, and disulphide/total thiol ( ...
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2018 - 2020 This website and its content is copyright of EFLM. All rights reserved. Any redistribution or reproduction of part or all of the contents in any form is prohibited other than the following: you may print or download to a local hard disk extracts for your personal and non-commercial use only you may copy the content to individual third parties for their personal use, but only if you acknowledge the website as the source of the material You may not, except with our express written permission, distribute or commercially exploit the content. Nor may you transmit it or store it in any other website or other form of electronic retrieval system. ...
MCV measurement related to red blood cells (RBCs) size and is part of the Complete Blood Count (CBC), a frequently requested test ordered for a variety of health conditions.Mean corpuscular volume (MCV) is a calculation of the RBCs average size. The MCV is increased if RBCs are larger than normal (macrocytic), for example in anemia caused by vitamin B12 deficiency. When the MCV is low RBCs are smaller than normal (microcytic) as is found in iron deficiency anemia or thalassemia.Medical Tests Analyzer labtest bloodtest What does the test result mean?
Eight adult standardbred horses were used. All horses received a single injection of 0, 3, 6, and 10 mg/kg of PPS at the beginning of each treatment week for 4 weeks so that by the end of the study all horses had received all four doses of PPS. Blood samples were collected at 0, 1, 2, 3, 4, 6, 8, 12, 24, 48, and 168 h after each weekly injection of PPS. Variables measured were packed cell volume, haemoglobin, red blood cell count, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, platelet count, white cell count, neutrophil count, lymphocyte count, eosinophil count, monocyte count, serum protein, fibrinogen, prothrombin time, and activated partial thromboplastin time (PTT). Data were analysed using an ANOVA. Significance was set at P , 0.05 ...
Blood profiles Haematology values are shown in Table 4. There was no significant change to the blood profile with T. bicornis infection, i.e. no significant change in haematocrit, red blood corpuscles (RBCs), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC) or platelets (PLTs) (Table 4). There was a slight elevation in white blood corpuscles count (WBC) (leucocytosis) in infected animals, but the difference was not significant (P = 0.068; Mann-Whitney non-parametric test). DISCUSSION The prevalence of T. bicornis in the KNP white rhinoceros population is similar to that reported in Zululand (northern part of KwaZulu-Natal)1. The RLB hybridisation assay was not able to detect B. bicornis in any of the samples. These could be either true negative results or due to a very low B. bicornis parasitaemia which was below the detection limit of the test. Blood smears of a debilitated black rhinoceros in KNP showed erythrocytes ...
Blood profiles Haematology values are shown in Table 4. There was no significant change to the blood profile with T. bicornis infection, i.e. no significant change in haematocrit, red blood corpuscles (RBCs), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC) or platelets (PLTs) (Table 4). There was a slight elevation in white blood corpuscles count (WBC) (leucocytosis) in infected animals, but the difference was not significant (P = 0.068; Mann-Whitney non-parametric test). DISCUSSION The prevalence of T. bicornis in the KNP white rhinoceros population is similar to that reported in Zululand (northern part of KwaZulu-Natal)1. The RLB hybridisation assay was not able to detect B. bicornis in any of the samples. These could be either true negative results or due to a very low B. bicornis parasitaemia which was below the detection limit of the test. Blood smears of a debilitated black rhinoceros in KNP showed erythrocytes ...
My blood work is bad. My platelets are up and down, mostly down. My white blood cells are extremely low, and something about my red cell distribution width, I understood that too mean they are abnormal...
Hypochromic anemia is a generic term for any type of anemia in which the red blood cells (erythrocytes) are paler than normal. (Hypo- refers to less, and chromic means color.) A normal red blood cell will have an area of pallor in the center of it; it is biconcave disk shaped. In hypochromic cells, this area of central pallor is increased. This decrease in redness is due to a disproportionate reduction of red cell hemoglobin (the pigment that imparts the red color) in proportion to the volume of the cell. Clinically the color can be evaluated by the Mean Corpuscular Hemoglobin (MCH) or Mean Corpuscular Hemoglobin Concentration (MCHC). The MCHC is considered the better parameter of the two as it adjusts for effect the size of the cell has on its color. Hypochromia is clinically defined as below the normal MHC reference range of 27-33 picograms/cell in adults or below the normal MCHC reference range of 33-36 g/dL in adults. Red blood cells will also be small (microcytic), leading to substantial ...
What is it? Mean corpuscular hemoglobin (abbreviated as MCH) is an estimate of the amount of hemoglobin in an average red blood cell. Hemoglobin is a substance in the blood that carries oxygen to the cells in the body from the lungs. High hemoglobin content is often referred to as hyperchromia, and low content, hypochromia.…
and monitored for changes in the blood profile using a haematological analyser. A chronic infection lasting between 48 and 112 days was observed. Microcytic hypochromic anaemia, which was characterized by a decline in packed cell volume (PCV), red blood cell (RBC) numbers, mean corpuscular volume (MCV) and mean corpuscular haemoglobin concentration (MCH) developed at an early stage, and persisted throughout the infection. The mean platelet counts declined significantly from 3 x 105/μl (day 0 post infection) to 6.8 x 104/μl (day 7 post infection) and remained low in all the animals. However, the mean platelets volume rose during the course of the infection. An initial decline in total white blood cell (WBC) counts occurred between day 0 and 7 (3.1 x 106/μl) and remained low up to day 35 post infection (3.5 x 106/μl). This was followed by an increase in WBC counts, principally associated with increased lymphocyte numbers. It is concluded that microcytic hypochromic anaemia, thrombocytopaenia ...
The erythrocyte osmotic fragility and other erythrocyte indices in fowls of two different age groups (7-9 week-old and 49 week-old) were studied using Nera Black strain usually raised co...
The aim of the study was to determine the prevalence of equine infectious anemia in the municipalities of Cachoeira do Arari, Salvaterra, Santa Cruz do Arari and Soure, in the Marajó Island, State of Pará, Brazil. For serological survey were selected 349 samples collected from June 2012 to March 2013, tested by agar gel immunodiffusion. Blood count was performed in 65 samples and biochemical examinations in 70, in which was researched urea, creatinine, aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transferase, alkaline phosphatase, total bilirubin and direct bilirubin. A prevalence of 24.06% (84/349) was verified. The average number of red blood cells was significantly lower in seropositive animals in relation to the seronegative ones and there was no significant difference in mean results of hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, platelets, in the white blood cell count, as well as in the biochemical examination. The ...
Different conditions can cause an abnormality in a blood count. Therefore, if an abnormality is found, you often need further tests to find the cause. A full blood count (FBC) test is one of the most common blood tests done.
Question - Have had full blood count. What does reports indicate?. Ask a Doctor about diagnosis, treatment and medication for Anemia, Ask a Gastroenterologist
1. Oxygen-binding, plasma and intra-erythrocytic pH, and haemoglobin, 2,3-diphosphoglycerate and inorganic phosphate concentrations were measured in sixty-two healthy non-smokers aged between 18 and 89 years.. 2. P50 (oxygen tension at 50% oxygen saturation) expressed at plasma pH 7·40 and Pco2 5·33 kPa showed a positive correlation with age.. 3. This correlation of P50 with age was closer when P50 was expressed at a constant intra-erythrocytic pH 7·20. On average P50 at intra-erythrocytic pH 7·20 increased from 3·59 kPa at 20 years to 3·96 kPa at 90 years of age.. 4. 2,3-Diphosphoglycerate, inorganic phosphate, haemoglobin and mean corpuscular haemoglobin concentrations did not correlate with P50 or with age.. ...
Identifying causal variants and genes from human genetic studies of hematopoietic traits is important to enumerate basic regulatory mechanisms underlying these traits, and could ultimately augment translational efforts to generate platelets and/or red blood cells in vitro. To identify putative causal genes from these data, we performed computational modeling using available genome-wide association datasets for platelet and red blood cell traits. Our model identified a joint collection of genomic features enriched at established trait associations and plausible candidate variants. Additional studies associating variation at these loci with change in gene expression highlighted Tropomyosin 1 (TPM1) among our top-ranked candidate genes. CRISPR/Cas9-mediated TPM1 knockout in human induced pluripotent stem cells (iPSCs) enhanced hematopoietic progenitor development, increasing total megakaryocyte and erythroid cell yields. Our findings may help explain human genetic associations and identify a novel genetic
Abstract Background: Serum gamma-glutamyltransferase (GGT) and erythrocyte mean corpuscular volume (MCV) are well-known biological markers of excessive ethanol consumption. Methods: The beverage-specific effects of ethanol consumption on GGT level and MCV value were analyzed cross-sectionally and retrospectively among middle-aged Japanese men who underwent a retirement health checkup (n=974). Results: Both ...
Mice that are homozygous for the targeted mutation exhibit slightly increased red blood cell counts, mean corpuscular hemoglobin, hematocrit and mean corpuscular volume when compared to wild-type controls. Homozygotes have diminished antigen-induced granulation tissue formation.
Specific Proteins Liquid (minimum 1 mL) or lyophilized samples (1 mL) of human sera with added analytes of human origin. 4 or 12 surveys per year. One sample per survey in monthly program (SP12), two samples per survey in quarterly program (SP4). Analytical parameters Albumin, Alpha-1-acid glycoprotein, Alpha-1-antitrypsin, Alpha-2-macroglobulin, ASO, Beta-2-microglobulin, C3, C4, Ceruloplasmin, CRP (C-Reactive Protein), Haptoglobin, IgA, IgE, IgG, IgM, Prealbumin, RF, TransferrinHemogram 2 liquid samples (minimum 2.5 mL) of whole blood. The samples contain stabilized human red blood cells, white blood cells and platelets of human and/or non-human analogs. 4 or 12 surveys per year. One sample per survey in monthly program (HEM12), two samples per survey in quarterly program (HEM4). Analytical parameters HCT (hematocrit), HGB (hemoglobin), MCH (mean corpuscular hemoglobin), MCHC (mean cellular hemoglobin concentration), MCV (mean corpuscular volume), MPV (mean platelet volume), PLT (platelets), ...
Objectives: This study aimed to investigate the effects of codeine administration on some haematological and biochemical indices in rats.. Materials and Methods: Therapeutic dose (5 mg/kg/day), high dose (25 mg/kg/day) and extreme dose (50 mg/kg/day) of codeine were administered orally to rats for 28 days. Twenty-four hours after the last codeine administration, blood, liver and kidney were removed from the animals after an overnight fast and analysed for their haematological and biochemical parameters.. Results: Results obtained revealed that codeine administration significantly reduced the levels of white blood cells (WBC), red blood cell (RBC) and platelet count (PLT) and increased the levels of mean corpuscular haemoglobin (MCH) and mean corpuscular volume (MCV)while it resulted in non-significant changes in other haematological parameters examined when compared with control rats. Codeine intake significantly increased plasma levels of alkaline phosphatase (ALP), aspartate aminotransferase ...
This study investigated the possible toxicity of consumption of the leaf by determining a variety of serum biochemical parameters in liver and renal function tests, haematological and physical parameters. A 5 week repeated dose toxicity of Jatropha tanjorensis leave powder was carried out in rabbits. Forty animals, male and female, were administered feed mash plus ground J. tanjorensis leaf powder in graded concentrations of 0, 5, 10 and 25%. All rabbits survived at the end of the study and results showed no significant alteration in average body weight in the treatment groups when compared with the control group. The haemoglobin, hematocrit, platelets and platelet cell distribution width in the female group, showed significant increase between the control and the treated groups. This is an indication of an improved bone marrow function. No severe histopathologic indicator was recorded ...
Wherever we are in the world there never seems to be enough money for healthcare provision. So the key is to make what resources we have go as far as possible. Any laboratory test that we request should always be preceded by the questions Why are we making the request, what are the possible results and what decisions might those results lead us to make? Then we should ask Have we gained all possible information from that test?. A simple examination of the blood (with an Erythrocyte Sedimentation Rate / ESR) is probably the best example of this approach. It may appear very limited but a great deal of information can be obtained about systemic disease. Most hospitals and health centres have the facilities for these tests.. The commoner blood count and blood film abnormalities can be considered under the headings of chronic disorders, infections and diseases of the various systems. (Primary haematological diseases are excluded from the present discussion).. ...
The values in a normal blood count vary for the separate components in blood. In addition, results are somewhat different among laboratories, according to MedicineNet.com. For instance, a typical...
Cold agglutinins Transfusions. Chemotherapy-not all drugs AZT therapy. Hyperglycemia-transient shifts. Cold agglutinins Transfusions. Chemotherapy-not all drugs AZT therapy. Hyperglycemia-transient shifts. 26 Part I • Basic Hematology Principles poikilocytosis (variation in shape) in a peripheral smear. The RDW is derived as follows:. (Standard deviation of RBC. volume/mean MCV) X 100. The normal value for RDW is 11.5% to 14.5%. The standard deviation of red cell volume is derived from size histogram data that plot red cell size after a large number of red cells has been analyzed by the instrument. The usefulness of the RDW is that in many cases the RDW will become abnormal earlier in the anemia process than the MCV Because many anemias (like iron deficiency anemias) develop over a period of time, this parameter may provide a sensitive indicator of red blood size change16 before the red cell indices become overtly abnormal.. The final item in the CBC is a platelet count. Information regarding ...
MCV Blood Test: MCV stands for mean corpuscular volume. There are three main types of corpuscles (blood cells) in your blood-red blood cells, white blood cells, and platelets. An MCV blood test measures the average size of your red blood cells, also known as erythrocytes. Red blood cells move oxygen from your lungs to every… (0 comment) ...
What does erythrocyte mean? erythrocyte is defined by the lexicographers at Oxford Dictionaries as A red blood cell, which (in humans) is typically a biconcave disc without a nucleus...
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Macrocytosis is a term used to describe erythrocytes that are larger than normal, typically reported as mean cell volume (MCV) greater than 100 fL. The amount of hemoglobin increases proportionately with the increase in cell size.
BioAssay record AID 828344 submitted by ChEMBL: Open TG-GATES: Regimen: Daily Repeat; Time: 4 day; Dose: High; Route: subcutaneous injection | Dataset: Hematology; Assay: MCV (Ery. Mean Corpuscular Volume); Study_ID: 693/13.
BioAssay record AID 821821 submitted by ChEMBL: Open TG-GATES: Regimen: Single; Time: 24 hr; Dose: Low; Route: intravenous injection | Dataset: Hematology; Assay: MCV (Ery. Mean Corpuscular Volume); Study_ID: 454/8.
"RBC indices: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved May 13, 2020. Tønnesen H, Hejberg L, Frobenius S, ... Andersen J (1986). "Erythrocyte Mean Cell Volume-Correlation to Drinking Pattern in Heavy Alcoholics". Acta Med Scand. 219 (5 ... and dividing that product by the number of erythrocytes (red blood cells) in that volume. The mean corpuscular volume is a part ...
"Compound heterozygous hemochromatosis genotype predicts increased iron and erythrocyte indices in women". Clinical Chemistry. ...
... erythrocyte deformability MeSH G09.188.250.350 - erythrocyte indices MeSH G09.188.250.400 - hematocrit MeSH G09.188.250.640 - ... erythrocyte aggregation MeSH G09.188.261.454 - erythrocyte aging MeSH G09.188.261.544 - hematopoiesis MeSH G09.188.261.544.414 ... erythrocyte volume MeSH G09.330.553.400.214.610 - plasma volume MeSH G09.330.553.400.280 - cardiac output MeSH G09.330.553.400. ... erythrocyte count MeSH G09.188.250.161.330.725 - reticulocyte count MeSH G09.188.250.161.595 - leukocyte count MeSH G09.188. ...
... erythrocyte aggregation MeSH E01.450.375.230 - erythrocyte indices MeSH E01.450.375.300 - figlu test MeSH E01.450.375.400 - ... erythrocyte count MeSH E01.450.375.107.330.725 - reticulocyte count MeSH E01.450.375.107.595 - leukocyte count MeSH E01.450. ...
In New Orleans, Wintrobe pioneered new ways of measuring the hematocrit, including what are now known as Wintrobe indices: mean ... Wintrobe, M. M. (1990). "The size and hemoglobin content of the erythrocyte. Methods of determination and clinical application ... "The Erythrocyte in Man". Initially working in Johns Hopkins Hospital, where he served on the faculty, he was appointed as ...
Normal Values: RBC, Hgb, Hct, Indices, RDW, Platelets, and MPV (Conventional Units) Archived 2011-07-27 at the Wayback Machine ... Böttiger LE, Svedberg CA (1967). "Normal erythrocyte sedimentation rate and age". Br Med J. 2 (5544): 85-87. doi:10.1136/bmj. ... "Simple rule for calculating normal erythrocyte sedimentation rate". British Medical Journal. 286 (6361): 266. doi:10.1136/bmj. ...
Erythrocyte fragility. *Blood substitute. *Packed red blood cells. *Red blood cell indices ... Red blood cells, also known as RBCs, red cells,[1] red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek ... Harrison, K. L. (1979). "Fetal Erythrocyte Lifespan". Journal of Paediatrics and Child Health. 15 (2): 96-97. doi:10.1111/j. ... Föller M, Huber SM, Lang F (October 2008). "Erythrocyte programmed cell death". IUBMB Life. 60 (10): 661-8. doi:10.1002/iub.106 ...
The cytoplasm of erythrocytes is rich in hemoglobin, an iron-containing biomolecule that can bind oxygen and is responsible for ... Altitude training Blood substitute Red blood cell indices Serum (blood) Er blood group collection Vinay Kumar; Abul K. Abbas; ... In plasma about 5% of CO2 is in physical solution 94% as bicarbonate and 1% as carbamino compounds; in the erythrocytes the ... Approximately 2.4 million new erythrocytes are produced per second in human adults. The cells develop in the bone marrow and ...
Jones GL, Woodbury DM: Spin-label study of phenothiazine interactions with erythrocyte ghost membranes: a possible membrane- ... Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices". Chem Inf. Comput. Sci. 41: 1488-1493. PMID ...
C-reactive protein and erythrocyte sedimentation rate (ESR) can also be used look for signs of inflammation. Infants and ... Raynor P, Rudolf MC (May 2000). "Anthropometric indices of failure to thrive". Archives of Disease in Childhood. 82 (5): 364- ...
Royds JA, Timperley WR, Taylor CB (December 1981). "Levels of enolase and other enzymes in the cerebrospinal fluid as indices ... Hoorn RK, Flikweert JP, Staal GE (November 1974). "Purification and properties of enolase of human erythrocytes". International ... and has since been isolated from a variety of sources including human muscle and erythrocytes. In humans, deficiency of ENO1 is ...
Obese rats showed significant increases in weight gain, adipose tissue mass, and adiposity and atherogenic indices, and ... polychromatic erythrocytes) and peripheral blood (reticulocytes) cells. Using mammalian cell lines: lung fibroblasts (Chinese ...
In congestive hepatopathy there are erythrocytes and a greater amount of fibrosis in the tissue surrounding the hepatic veins. ... Portal vein pulsatility can be quantified by pulsatility indices (PI), where an index above a certain cutoff indicates ...
Erythrocyte Sedimentation Rate. Indicates the time it takes for red blood cells to move down a tube. This shows signs of ...
... erythrocytes) of almost all vertebrates[4] (the exception being the fish family Channichthyidae[5]) as well as the tissues of ... "Is hemoglobin an essential structural component of human erythrocyte membranes?". J Clin Invest. 42 (4): 581-88. doi:10.1172/ ...
If the blood is kept at warmer temperatures, schizonts will rupture and merozoites invading erythrocytes will mistakenly give ... the buildup of acid in the sample will cause the parasitised erythrocytes to shrink and the parasite will roll up, simulating ...
... trauma severity indices MeSH E05.318.308.940.968.875.125 - abbreviated injury scale MeSH E05.318.308.940.968.875.250 - glasgow ... erythrocyte count MeSH E05.200.500.195.107.330.725 - reticulocyte count MeSH E05.200.500.195.107.595 - leukocyte count MeSH ...
... and dexamethasone on insulin binding of human erythrocytes". The Journal of Clinical Endocrinology and Metabolism. 55 (5): 910- ... and they usually have high glycemic indices.[22] Overconsumption of cheap sugar-rich meals and beverages have been proposed as ...
Red Blood Cell IndicesEdit. RBC Indices are typically calculated from other measured RBC parameters. They include the MHC, MCHC ... erythrocytes), and platelets (thrombocytes). Abnormally high or low counts may indicate the presence of many forms of disease, ... "Red Blood Cell (RBC) Indices: Definitions and Calculations - LabCE.com, Laboratory Continuing Education". www.labce.com.. ... Various Red blood cell indices (parameters calculated from other CBC results) are often reported in addition to cell counts and ...
Adherence of M. pneumoniae to a host cell (usually a respiratory tract cell, but occasionally an erythrocyte or urogenital ... August 2004). "Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in ... Attachment of M. pneumoniae to erythrocytes permits diffusion of hydrogen peroxide from the bacteria to the host cell without ...
Ruocco L, Del Corso L, Romanelli AM, Deri D, Pentimone F (April 2001). "New hematological indices in the healthy elderly". ... From left to right: human erythrocyte, activated platelet, leukocyte.. Inhibition[edit]. The intact endothelial lining inhibits ...
2001). "New hematological indices in the healthy elderly". Minerva medica. 92 (2): 69-73. PMID 11323567.. ... From left to right: human erythrocyte, activated platelet, leukocyte.. InhibitionEdit. The intact endothelial lining inhibits ...
... erythrocyte sedimentation rate, and serological testing for coeliac disease Abdominal ultrasound (to exclude gallstones and ... and also affecting coeliac diagnostic indices.3,4 Misdiagnosis of intestinal diseases can lead to secondary problems such as ...
Erythrocyte fragility. *Blood substitute. *Packed red blood cells. *Red blood cell indices ... Red blood cells, also known as RBCs, red cells,[1] red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek ... Harrison, K. L. (1979). "Fetal Erythrocyte Lifespan". Journal of Paediatrics and Child Health. 15 (2): 96-97. doi:10.1111/j. ... Föller M, Huber SM, Lang F (October 2008). "Erythrocyte programmed cell death". IUBMB Life. 60 (10): 661-8. doi:10.1002/iub.106 ...
Erythrocyte indices definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look ...
What is erythrocyte indices? Meaning of erythrocyte indices medical term. What does erythrocyte indices mean? ... Looking for online definition of erythrocyte indices in the Medical Dictionary? erythrocyte indices explanation free. ... red blood cell indices (red cell indices) erythrocyte indices.. refractive index the refractive power of a medium compared with ... erythrocyte indices. Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia.. Related to erythrocyte indices: ...
What hematologic factors do the erythrocyte indices provide information about? List one example for each index in which a ... 1. What hematologic factors do the erythrocyte indices provide information about? List one example for each index in which a ... 1. What hematologic factors do the erythrocyte indices provide information about? List one example.. ...
Download Free Full-Text of an article THE EFFECTS OF AEROBIC EXERCISE ON ERYTHROCYTE INDICES IN CANCER PATIENTS AFTER ... The purpose of this study was to determine the effects of aerobic exercise on erythrocyte indices in cancer patients after ... THE EFFECTS OF AEROBIC EXERCISE ON ERYTHROCYTE INDICES IN CANCER PATIENTS AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL ... THE EFFECTS OF AEROBIC EXERCISE ON ERYTHROCYTE INDICES IN CANCER PATIENTS AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL ...
Comparison of erythrocyte indices to differentiate between iron deficiency and alpha-thalassaemias in children with ... The remaining discrimination erythrocyte indices were calculated using the red blood cell indices as defined in Table 1. ... For the calculated erythrocyte indices, we used the cut-off values commonly described in the literature to study their ... ABSTRACT Erythrocyte indices used to differentiate between iron deficiency anaemia (IDA) and thalassaemias have been studied ...
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Tag Archives: erythrocyte indices. Hematologic features of beta-globin gene mutation type (βo) with homozygous beta thalassemia ... Erythrocyte indices, HbF, HbA2 levels were compared between the two groups. FSC 44/(-C) mutations were detected in patients. Hb ...
As a result, averaged Hb, Hct and erythrocyte counts were used to calculate the RBC indices MCV, MCH and MCHC. Consequently, ... Erythrocyte morphology. The H:W of erythrocytes from normoxia-reared embryos and larvae was low and stable between Stages 27 ... 5B and 5C show oval erythrocytes from normoxia-reared Stage 35 larvae and round erythrocytes from hypoxia-reared Stage 35 ... Although Iuchi (Iuchi, 1973a) previously tracked the turnover of embryonic erythrocytes for adult erythrocytes, our study is ...
Sources Of Error In The Calculation Of Erythrocyte Indices. Sources Of Error In The Calculation Of Erythrocyte Indices. ... The RBC indices can help your doctor determine the cause if your doctor thinks you have anemia. What is trapped plasma? X Sign ... If youre found to have anemia, the RBC and the RBC indices can help to determine whats causing your anemia. Such ... The MCHC cannot exceed the normal value since the erythrocyte cannot be supersaturated with hemoglobin. Meta Cells Cbc Your ...
Cryohemolysis, erythrocyte osmotic fragility, and supplementary hematimetric indices in the diagnosis of hereditary ... The HbS erythrocytes in one patient were sensitive in the CHT. This effect was described by Streichman et al., who found it to ... The behavior of erythrocytes in the CHT does not depend only on membrane protein defects but also on the depletion of AQP1. ... The erythrocyte osmotic fragility (EOF) test determines the concentration of sodium chloride at which 50% of the fresh and ...
Erythrocyte Indices and Fragility Tests. ERYTHROCYTE INDICES. By using accurately determined red blood cell counts, hematocrits ... and erythrocyte count ensure reliable indices. The following procedures are recommended:. *Erythrocyte count--two separate ... The MCHC is the most valid of the indices since it does not require the erythrocyte count in its deviation. It is a good index ... Calculation of Erythrocyte Indices.. *Mean corpuscular volume (MCV)--The average volume of the individual red blood cell. ...
... indices are part of the complete blood count (CBC) test. They are used to help diagnose the cause of anemia, a condition in ... Erythrocyte indices; Blood indices; Mean corpuscular hemoglobin (MCH); Mean corpuscular hemoglobin concentration (MCHC); Mean ... The RBC indices test measures how well the RBCs do this. The results are used to diagnose different types of anemia. ... Red blood cell (RBC) indices are part of the complete blood count (CBC) test. They are used to help diagnose the cause of ...
Erythrocyte Form, Function, and Indices.. 11. Erythrocyte Abnormalities.. 12. Anemias and Polycythemias. ...
Measuring indices can help diagnose different forms of anemia. Learn more. ... indices measure the size, shape, and quality of your red blood cells. ... Red blood cells, also known as erythrocytes, carry oxygen from your lungs to every cell in your body. Your cells need oxygen to ... What are red blood cell (RBC) indices?. Red blood cell (RBC) indices measure the size, shape, and quality of your red blood ...
Anaemia; anaemia; diagnosis; differential; erythrocyte indices; hypochromic microcytic; iron deficiency; thalassemia. PMID:. ...
Keywords: COPD, ESR, Red blood cell indices Abstract. Objective: To find association of red blood cell indices and erythrocyte ... Kanwal, A., Bashir, A., Gohier, A., & Habib, B. (2021). ASSOCIATION OF RED BLOOD CELL INDICES AND ERYTHROCYTE SEDIMENTATION ... ASSOCIATION OF RED BLOOD CELL INDICES AND ERYTHROCYTE SEDIMENTATION RATE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) ... When association of COPD was seen with different red blood cell indices then it was striking to find out that the mean ...
Erythrocyte indices in a large cohort of β-thalassemia carrier: Implication for population screening in an area with high ... We have examined whether these indices are effective in screening of β-thalassemia in Thailand where thalassemia is prevalence ...
The indices of D9D and D6D from erythrocyte membrane phospholipids and the proportion of saturated fatty acids were increased ... Anthropometry, serum lipids, clinical parameters, and erythrocyte membrane phospholipid fatty acid data were obtained from a ... We aimed to investigate the association between fatty acids in erythrocyte membrane phospholipids and CVD risk factors in ... The indices of D9D and D6D from erythrocyte membrane phospholipids and the proportion of saturated fatty acids were increased ...
Objective To investigate the correlation between the erythrocyte indices and the genotypes of alpha thalassemia.Methods337 ... Study on correlation between erythrocyte indices and genotype in cases with alpha-thalassemia / 中华检验医学杂志 ... Study on correlation between erythrocyte indices and genotype in cases with alpha-thalasse ... and 154 healthy adults were randomly choosed as normal control The erythrocyte indices involving in RBC,Hb,MCV,MCH,MCHC and RDW ...
Cryohemolysis, erythrocyte osmotic fragility, and supplementary hematimetric indices in th Cryohemolysis, erythrocyte osmotic ... Anemia , Anemia, Hemolytic , Diagnosis , Erythrocyte Indices , Erythrocytes , Hemolysis , Humans , Osmotic Fragility , ... Erythrocyte Indices / Erythrocytes / Hemolysis / Anemia / Anemia, Hemolytic Language: English Journal: Blood Research Year: ... Erythrocyte Indices / Erythrocytes / Hemolysis / Anemia / Anemia, Hemolytic Language: English Journal: Blood Research Year: ...
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult ... B-Erythrocytes (females 3.94-5.16 x 10(12)/L, males 4.25-5.71 x 10(12)/L), B-EVF (females 0.348-0.459, males 0.395-0.500), B- ...
These five indices were compared with two non-invasive biomarkers, erythrocyte sedimentation rate (ESR) and C-reactive protein ... These five indices were compared with two non-invasive biomarkers, erythrocyte sedimentation rate (ESR) and C-reactive protein ... These five indices were compared with two non-invasive biomarkers, erythrocyte sedimentation rate (ESR) and C-reactive protein ... These five indices were compared with two non-invasive biomarkers, erythrocyte sedimentation rate (ESR) and C-reactive protein ...
Erythrocyte Indices* * Female * Humans * Hypertension, Pulmonary / blood * Hypertension, Pulmonary / etiology * Hypertension, ...
Erythrocyte Indices * Female * Hemoglobins / biosynthesis * Humans * Infant * Infant, Newborn * Iron / therapeutic use ...
Effects of AHSP loss on erythrocyte indices of adult β-thalassemic (β-globin+/th-3) mice ... Oxidative stress in AHSP-/- erythrocytes. (A) Relative ROS levels in erythrocytes at baseline and with added H2O2. ROS were ... B) Erythrocyte survival kinetics determined by biotin labeling. Circulating erythrocytes in 5 animals of each genotype were ... Differing erythrocyte membrane skeletal protein defects in alpha and beta thalassemia. J. Clin. Invest. 1989. 83:404-410. View ...
1.hct 59%; rbc 5 million/mm3; hgb 14g; erythrocyte indices wnl. 2.wbc 15, 000/mm3. no shift to the left.. 3.platelets normal. 4 ... 1. Hct 59%; RBC 5 million/mm3; Hgb 14g; erythrocyte indices WNL. 2. WBC 15, 000/mm3. No shift to the left.. 3. Platelets normal ...
6 Lipidomics of Erythrocyte Membranes 105. 6.1 Erythrocyte as a Comprehensive Health Biomarker 107 ... 6.3 Lipid Biosynthesis and Related Indices 120. 6.4 The Individuation of Molecular Indicators 122 ...
What is target erythrocyte? Meaning of target erythrocyte medical term. What does target erythrocyte mean? ... Looking for online definition of target erythrocyte in the Medical Dictionary? target erythrocyte explanation free. ... erythrocyte indices,. n.pr the standard values of red blood cell numbers, morphologic characteristics, and behavior in ... immature erythrocyte. Any incompletely developed erythrocyte. orthochromatic erythrocyte. An erythrocyte that stains with acid ...
Erythrocyte Indices. Ferritins / blood. Food, Fortified*. Hemoglobins / analysis. Humans. Immunity / drug effects. Infant. ...
Erythrocyte Indices. Female. Foot Ulcer / chemically induced*, pathology, therapy. Histological Techniques. Humans. Hydroxyurea ...
  • In chronic hypoxia (30% of oxygen saturation), stage-matched embryos and larvae possessed half the Hb concentration, erythrocyte counts and hematocrit observed in normoxia. (biologists.org)
  • Accurate individual determinations of hemoglobin, hematocrit, and erythrocyte count ensure reliable indices. (free-ed.net)
  • The measure is obtained by multiplying a volume of blood by the proportion of blood that is cellular (the hematocrit), and dividing that product by the number of erythrocytes (red blood cells) in that volume. (wikipedia.org)
  • Red blood cell indices are calculations derived from the red blood cell count, hemoglobin and hematocrit that aid in the diagnosis and classification of anemia. (encyclopedia.com)
  • No changes to the hematocrit, hemoglobin or erythrocyte levels or to the hematimetric indices of the pirarucus were observed. (scielo.br)
  • Hematological indices such as immature erythrocyte percentage (%), hematocrit and hemoglobin concentrations, glucose, plasma ammonia and osmolality have been used as markers to evaluate fish health under various toxic exposures [11,12,31,34-40]. (thefreedictionary.com)
  • the average hemoglobin concentration in a given volume of packed red blood cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices. (drugs.com)
  • Automated analyzers are used to count cells, measure hemoglobin levels, and calculate parameters such as the hematocrit and erythrocyte indices. (thefreedictionary.com)
  • Conclusions: CRP and ESR levels were modestly correlated with endoscopic activity indices in UC patients. (elsevier.com)
  • We compared fatigue scores, morning stiffness and pain scores, Clinical Disease Activity Indices, erythrocyte sedimentation rates, C Reactive Protein, and profile of adverse effects. (hindawi.com)
  • MAIN OUTCOME MEASURES: Using flow cytometry, we analyzed erythrocyte and reticulocyte indices. (arctichealth.org)
  • Red blood cell count, haemoglobin concentration, haematocrit, reticulocyte population and erythrocyte osmofragility were used as erythrocyte indices. (scialert.net)
  • The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased. (bioportfolio.com)
  • When association of COPD was seen with different red blood cell indices then it was striking to find out that the mean corpuscular hemoglobin concentration (MCHC) was significantly associated (p=0.03). (pafmj.org)
  • Indices of Pb exposure, RBC counts, haemoglobin concentration (Hb), haematocrit (PCV), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) of rabbits were investigated. (springermedizin.de)
  • Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. (bioportfolio.com)
  • Blood of each sample is used to determine hemoglobin concentration, erythrocyte count, red cell indices, serum MDA, serum ALT and serum AST levels. (scopemed.org)
  • Increased red blood cell destruction causes the main clinical features of typical HS: evidence of hemolysis with anemia, reticulocytosis, splenomegaly, jaundice, gallstone formation, spherocytes in a peripheral blood smear, and increased osmotic fragility of the erythrocytes. (bloodresearch.or.kr)
  • The typical clinical picture of HS combines signs and symptoms of hemolysis (anemia, jaundice, reticulocytosis, gallstones, splenomegaly) with spherocytosis (spherocytes on the peripheral blood smear with increased erythrocyte osmotic fragility) and a positive family history. (renalandurologynews.com)
  • This measurement is not enough to make a diagnosis, so RDW results are usually combined with the results of other indices and other blood tests. (medlineplus.gov)
  • The RBC indices can help your doctor determine the cause if your doctor thinks you have anemia. (alignedstrategy.com)
  • If you're found to have anemia, the RBC and the RBC indices can help to determine what's causing your anemia. (alignedstrategy.com)
  • Hereditary spherocytosis (HS) is a chronic hemolytic anemia characterized by microspherocytes in the peripheral blood and increased erythrocyte osmotic fragility (EOF). (bloodresearch.or.kr)
  • Erythrocytes in this form of anemia lyse easily in slight variations in the pH (acid). (free-ed.net)
  • If one or more of these indices are not normal, it may mean you have some type of anemia , a condition in which your body does not make enough healthy red blood cells. (medlineplus.gov)
  • The results of RBC indices are used to diagnose different types of anemia. (medlineplus.gov)
  • Hoffmann JJ, Urrechaga E, Aguirre U. Discriminant indices for distinguishing thalassemia and iron deficiency in patients with microcytic anemia: a meta-analysis. (medscape.com)
  • Erythrocyte Indices as Differential Diagnostic Biomarkers of Iron Deficiency Anemia and Thalassemia. (ithanet.eu)
  • Artesunate was shown to decrease hemoglobulin, erythrocyte and platelet count. (malariaworld.org)
  • Hereditary spherocytosis (HS) is a heterogeneous disorder in which abnormalities of the red blood cell membrane structural proteins lead to the loss of membrane surface area, resulting in hyperdense, spherically-shaped erythrocytes with reduced deformability and reduced shorter half-life. (bloodresearch.or.kr)
  • We aimed to investigate the association between fatty acids in erythrocyte membrane phospholipids and CVD risk factors in middle-aged Korean adults. (biomedcentral.com)
  • Anthropometry, serum lipids, clinical parameters, and erythrocyte membrane phospholipid fatty acid data were obtained from a registry. (biomedcentral.com)
  • This study was a retrospective cross-sectional study using data from patients who underwent a special health check-up consisting of anthropometrical measurements, blood chemistry, and analysis of erythrocyte membrane phospholipid fatty acid composition. (biomedcentral.com)
  • Activity of membrane-bound enzymes, passive penetration of ions in dose-dependent loading with cholesterol, effect of cholesterol high concentrations on the metabolic patterns in cytosol, viscosity of cell suspension were studied in erythrocytes. (msk.ru)
  • Passive cotransport of H+ and Cl- ions via erythrocyte membrane was increased with augmentation in viscosity of the cell suspension. (msk.ru)
  • Taganovich A.D., Oletskiĭ E.I., Kukhta V.K., Activity of membrane-bound enzymes, indices of metabolism in the cytoplasm and various physico-chemical properties of erythrocytes with increased cholesterol level, Voprosy meditsinskoi khimii, 1985, vol: 31(5), 75-80. (msk.ru)
  • In the present study, the effect of ingested Pb on erythrocyte membrane sialic acid content and osmotic fragility of New Zealand White (NZW) rabbits was studied. (springermedizin.de)
  • n-3 PUFAs levels were measured in membrane erythrocytes. (arctichealth.org)
  • The cell (or plasma) membrane plays an important role by permitting the passage of gases, ions, and water in the erythrocytes. (thefreedictionary.com)
  • On the surface of the lipoprotein membrane are specific glycoprotein antigens, or agglutinogens-the blood group factors responsible for the agglutination of erythrocytes. (thefreedictionary.com)
  • MCH mean corpuscular hemoglobin, the average hemoglobin load, represents the average amount of hemoglobin per erythrocyte. (spandidos-publications.com)
  • Onion supplementation, regardless of the variety, resulted in dose-dependent reductions in erythrocyte counts and Hb levels, while the white blood cell concentrations, particularly lymphocytes, were increased in pigs that consumed onions. (cambridge.org)
  • The word "not" was erroneously removed from the second sentence, which should have read: "It is not ideal to estimate iron stores from haemoglobin concentrations or erythrocyte indices. (bmj.com)
  • Erythrocyte indices in a large cohort of β-thalassemia carrier: Implication for population screening in an area with high prevalence and heterogene. (cdc.gov)
  • We have examined whether these indices are effective in screening of β-thalassemia in Thailand where thalassemia is prevalence and heterogeneous. (cdc.gov)
  • HS may be obscured in disorders that increase the surface to volume ratio of erythrocytes, such as obstructive jaundice, iron deficiency, ß-thalassemia trait or hemoglobin SC disease, and vitamin B 12 or folate deficiency. (renalandurologynews.com)
  • A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. (lsh.is)
  • Initially, RA disease activity evaluations were focused on separate measurement of relevant variables, including symptoms such as duration of morning stiffness, number of painful and oedematous joints and measurements to detect inflammatory activity, such as the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) [10]. (smw.ch)
  • 30-64y, 2004-2013, mean±SD follow-up time(y): 4.64 ± 0.93y], conducted linear mixed-effects regression models were conducted to test associations of inflammatory markers [C-reactive protein, Erythrocyte Sedimentation Rate (ESR), albumin, iron, and an inflammation composite score (ICS)] with longitudinal cognitive performance. (frontiersin.org)
  • The stages of differentiation of the red line starts from multipotent stem cells (also called hemocytoblasts), goes through common multipotent myeloid progenitors, unipotent stem cells, proerythroblasts (also called pronormoblast), basophilic normoblasts (also called erythroblast-secretes erythroferrone that inhibits the hepcidin secretion), intermediate normoblast-polychromatophilic, orthochrome normoblast (the nucleus is expelled) and reticulocytes (normally accounts for 1% of blood cells and lasts for 1-2 days until maturation to erythrocytes). (spandidos-publications.com)
  • However, the relationships between non-invasive biomarkers and invasive endoscopic severity indices remain poorly understood. (elsevier.com)
  • These five indices were compared with two non-invasive biomarkers, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels. (elsevier.com)
  • Similarly, exposure to Pb significantly decreased erythrocyte sialic acid content and increased the erythrocyte osmotic fragility of Pb-treated animals. (springermedizin.de)
  • Hereditary spherocytosis (HS) refers to a group of disorders characterized by spherical, doughnut-shaped erythrocytes with increased osmotic fragility. (renalandurologynews.com)
  • In rainbow trout development, a switch occurs from high-affinity embryonic hemoglobin (Hb) and round, embryonic erythrocytes to lower-affinity adult Hb and oval, adult erythrocytes. (biologists.org)
  • Embryonic erythrocytes are the only erythrocyte in the circulation until 1 day before hatching, when a turnover of embryonic for oval, adult erythrocytes begins. (biologists.org)
  • By 1 day post-hatch (15°C), erythropoiesis is initiated in the kidney and spleen, which produce immature adult erythrocytes that ultimately grow into mature adult erythrocytes ( Iuchi and Yamamoto, 1983 ). (biologists.org)
  • Erythrocyte formation ( erythropoiesis ) takes place in the red bone marrow in the adult, and in the liver, spleen, and bone marrow of the fetus. (thefreedictionary.com)
  • Approximately 75% of the body's iron circulates in erythrocytes, with a smaller proportion stored in hepatocytes for release when required. (springer.com)
  • Composite measures are frequently used to evaluate the disease activity score (DAS), including the response criteria of the American College of Rheumatology (ACR), the response criteria and the DAS according to the European League Against Rheumatism (EULAR) and the composite indices of disease activity (CIDsA): DAS, the index of disease activity based on 28 joints (DAS 28), the simplified disease activity index (SDAI) and the clinical disease activity index (CDAI). (smw.ch)
  • ABSTRACT Erythrocyte indices used to differentiate between iron deficiency anaemia (IDA) and thalassaemias have been studied mainly in countries with a high prevalence of IDA or beta-thalassaemias. (who.int)
  • We studied the predictive value and Youden index of several indices in 85 children aged 6 months to 12 years with microcytosis and/or hypochromia, with or without anaemia (determined by serum measurement of iron or therapeutic iron trial). (who.int)
  • The anaemia frequently observed in Pb poisoning is thought to result from the shortening of erythrocytes, life span and inhibition of key enzymes of haem synthesis [viz. (springermedizin.de)
  • Macrophages from the hematogenous marrow under the action of hepcidin release the sequestered iron to be provided to the erythrocyte progenitors for hem synthesis ( 3 , 4 ). (spandidos-publications.com)
  • The data support our hypothesis that chronic hypoxia delays the ontogenetic turnover of Hb and erythrocytes, but without the predicted functional consequences (i.e. higher than expected P 50 ). (biologists.org)
  • Zurück zum Zitat Ahyayauch H, Sansar W, Rendón-Ramírez A, Goñi FM, Bennouna M, Gamrani H (2013) Effects of chronic and acute lead treatments on the biophysical properties of erythrocyte membranes, and a comparison with model membranes. (springermedizin.de)
  • Erythrocyte indices, HbF, HbA2 levels were compared between the two groups. (ukrbiochemjournal.org)
  • A1C is influenced not only by blood glucose levels, but also by conditions that affect erythrocyte survival ( 3 ). (diabetesjournals.org)
  • There was no correlation of receptor levels with in vitro [ 3 H]thymidine labeling indices, terminal deoxynucleotide transferase levels, FAB classification, or sex. (aacrjournals.org)
  • 100 × 10 3 /cu mm, positive erythrocyte rosette test, central nervous system involvement, and mediastinal mass) were excluded, lower glucocorticoid receptor levels were still associated with higher risk of relapse ( p = 0.007). (aacrjournals.org)
  • Knowledge of a specific association between fatty acid indices and individual risk factors would allow detection of alterations that could contribute to CVD. (biomedcentral.com)
  • Associations between baseline erythrocyte n-3 polyunsaturated fatty ac" by Linda C. Tapsell, J O'Shea et al. (edu.au)
  • Called also red cell or red blood cell indices . (thefreedictionary.com)
  • The purpose of this study was to determine the effects of aerobic exercise on erythrocyte indices in cancer patients after autologous hematopoietic stem cell transplantation. (sid.ir)
  • Hb E is only found inside round, embryonic erythrocytes, which are produced in the intermediate cell mass and blood islands on the yolk sac ( Iuchi and Yamamoto, 1983 ). (biologists.org)
  • Erythrocyte count--two separate pipets and two to four counting chambers or electronic cell counting. (free-ed.net)
  • Red blood cell (RBC) indices are part of the complete blood count (CBC) test. (medlineplus.gov)
  • Red blood cell (RBC) indices measure the size, shape, and quality of your red blood cells. (medlineplus.gov)
  • Red blood cells, also known as erythrocytes, carry oxygen from your lungs to every cell in your body. (medlineplus.gov)
  • Red blood cell (RBC) indices are part of a complete blood count , a group of tests that measures various parts and features of your blood. (medlineplus.gov)
  • Why do I need red blood cell indices testing? (medlineplus.gov)
  • What happens during a red blood cell indices test? (medlineplus.gov)
  • You don't need any special preparations for a red blood cell (RBC) indices. (medlineplus.gov)
  • To find association of red blood cell indices and erythrocyte sedimentation rate (ESR) in COPD patients. (pafmj.org)
  • Hence it is concluded that the red blood cell indices and ESR have a strong association with COPD. (pafmj.org)
  • Nucleated red blood cell (RBC) precursors stimulated by erythropoietin form erythrocytes in the bone marrow. (thefreedictionary.com)
  • The progenitor cells undergo a marked reduction in cell volume starting at 900 fl for precursors and ending with 95 fl for mature erythrocytes. (spandidos-publications.com)
  • The values obtained are the erythrocyte indices which aid in the classification and study of anemias. (free-ed.net)
  • Wintrobe classified anemias into the following groups on the basis of the indices (Figure 7-2). (free-ed.net)
  • 30mg/d of Zn increased significantly serum and urinary Zn in middle-aged and older people, but no effect of Zn supplementation on erythrocyte Zn has been observed in the middle-aged and older groups. (europa.eu)
  • The effect of graded doses of aqueous leaf extract of Parquetina nigrescens on erythrocyte indices and serum electrolytes was studied for two weeks on rats following acute blood loss. (scialert.net)
  • In this chapter, we will demonstrate how microfluidic devices can be used to examine the vascular deformability of erythrocytes and agranular leukocytes. (intechopen.com)
  • It is useful to compare the calculated indices with a stained peripheral blood smear. (free-ed.net)
  • The presence of micronuclei in peripheral blood erythrocytes has been used as a biomarker of genotoxicity caused by pollutants since 70's (SCHMIDT, 1975). (thefreelibrary.com)
  • Results: The Pearson's correlation coefficients of CRP and ESR with endoscopic indices were r = 0.457 and 0.342 in the Powell-Tuck assessment, r = 0.503 and r = 0.402 in the Mayo Endoscopic Score, r = 0.507 and 0.408 in Hanauer's Sigmoidoscopic Index, r = 0.520 and 0.433 in the modified Baron Score, and r = 0.523 and 0.435 in the Rachmilewitz Endoscopic Activity Index. (elsevier.com)
  • Body mass index (BMI), waist circumference, HbA1c, fasting plasma glucose (FPG) and erythrocyte indices were measured. (wiley.com)
  • MCV, MCH, and MCHC indices. (free-ed.net)
  • The MCHC cannot exceed the normal value since the erythrocyte cannot be supersaturated with hemoglobin. (free-ed.net)
  • The MCHC is the most valid of the indices since it does not require the erythrocyte count in its deviation. (free-ed.net)
  • Newborns without G6PD deficiency also are at risk because of immature erythrocyte enzyme systems (glutathione instability). (thefreedictionary.com)
  • Folic acid supplementation at either dose did not affect the efficacy of methotrexate therapy as judged by joint indices and patient and physician assessments of disease. (annals.org)
  • Except for a positive relationship between FEP and certain pure tone threshold measures, none of the biomedical indices had a significant relationship to the nerve conduction velocities (NCV) or behavioral measures. (cdc.gov)
  • Mature mammalian and human erythrocytes lack the nucleus that is present in the early stages of their development-that is, in the erythroblasts. (thefreedictionary.com)
  • The average lifespan of an erythrocyte is 120 days and, every day, 200 billion red blood cells are released into circulation and 'withdrawn' respectively ( 1 ). (spandidos-publications.com)

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