The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.
Ability of ERYTHROCYTES to change shape as they pass through narrow spaces, such as the microvasculature.
The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.
Bleeding from the vessels of the retina.
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
The semi-permeable outer structure of a red blood cell. It is known as a red cell 'ghost' after HEMOLYSIS.
The phenomenon by which dissociated cells intermixed in vitro tend to group themselves with cells of their own type.
Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.
That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the microwave frequencies. They are used therapeutically as heat, and also to warm food in restaurants.
Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
Nanometer sized fragments of semiconductor crystalline material which emit PHOTONS. The wavelength is based on the quantum confinement size of the dot. They can be embedded in MICROBEADS for high throughput ANALYTICAL CHEMISTRY TECHNIQUES.
A genus of the family Heteromyidae which contains 22 species. Their physiology is adapted for the conservation of water, and they seldom drink water. They are found in arid or desert habitats and travel by hopping on their hind limbs.
The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
Examination of the interior of the eye with an ophthalmoscope.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
The blood vessels which supply and drain the RETINA.
An area approximately 1.5 millimeters in diameter within the macula lutea where the retina thins out greatly because of the oblique shifting of all layers except the pigment epithelium layer. It includes the sloping walls of the fovea (clivus) and contains a few rods in its periphery. In its center (foveola) are the cones most adapted to yield high visual acuity, each cone being connected to only one ganglion cell. (Cline et al., Dictionary of Visual Science, 4th ed)
The natural enzymatic dissolution of FIBRIN.
A metallocarboxypeptidase that removes C-terminal lysine and arginine from biologically active peptides and proteins thereby regulating their activity. It is a zinc enzyme with no preference shown for lysine over arginine. Pro-carboxypeptidase U in human plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.
Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis.
Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.
The plasma membrane of the egg.
The resistance that a gaseous or liquid system offers to flow when it is subjected to shear stress. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.

Power Doppler ultrasound scan imaging of the level of red blood cell aggregation: an in vitro study. (1/199)

PURPOSE: The purpose of this study was to evaluate the effect of the shear rate on red blood cell (RBC) aggregation with power Doppler ultrasound scanning (PDU), pulsed-wave Doppler scanning, and color Doppler flow imaging. METHODS: Equine and porcine blood were circulated with a steady flow in a phantom with a diameter of 9.52 mm. The color Doppler flow imaging mode was used to estimate the velocity profile and the shear rate across the tube. A transfer function that related the Doppler scan power, measured in gray level with the PDU method, to the power, measured in decibels with the pulsed-wave Doppler scan technique, was used to estimate the echogenicity of blood and the level of aggregation. RESULTS: For the four experiments reported, the power peaked at low shear rates probably because of increased RBC collisions and aggregation and then decreased thereafter because of disaggregation. The largest power variations were measured at shear rates of less than 40 seconds -1. At flow rates that varied between 75 and 500 mL/min, the echogenicity was low near the wall of the tube, increased toward the middle, and decreased at the tube center. The Doppler scan power was uniform across the tube at flow rates of 750 and 1000 mL/min. CONCLUSION: PDU is reliable to quantify the echogenicity of blood and the level of RBC aggregation. In comparison with other methods proposed to measure RBC aggregation, ultrasound scanning is applicable in vivo and may help to improve our basic understanding of the relationship between the hemodynamic of the circulation and RBC aggregation in human vessels.  (+info)

Erythrocyte-aggregating relapsing fever spirochete Borrelia crocidurae induces formation of microemboli. (2/199)

The African relapsing fever spirochete Borrelia crocidurae forms aggregates with erythrocytes, resulting in a delayed immune response. Mice were infected with B. crocidurae and monitored during 50 days after infection. Spirochetes were observed extravascularly at day 2 after infection. Two days later, inflammatory responses, cell death, and tissue damage were evident. The pathologic responses in lungs and kidneys were similar, whereas the symptoms in the brains were delayed, with a less pronounced inflammatory response. Microemboli were found in the blood vessels, possibly a result of the erythrocyte aggregation. The B. crocidurae invasion emerged more rapidly than has been described for Lyme disease-causing Borrelia species. In addition to erythrocyte rosetting, the presence of extravascular B. crocidurae indicates a novel route for these bacteria to propagate and cause damage in the mammalian host. The histopathologic findings in this study may explain the clinical manifestations of human relapsing fever.  (+info)

Hemorheologic variables in critical limb ischemia before and after infrainguinal reconstruction. (3/199)

PURPOSE: Plasma and whole blood viscosity are elevated in patients with intermittent claudication. The objectives of this study were to investigate whether critical limb ischemia influences hemorheologic variables and whether the rheologic variables in blood from the affected limb differ from the general circulation. We also intended to study whether successful infrainguinal reconstruction improved hemorheologic variables. METHODS: Ten consecutive patients with critical limb ischemia (CLI) underwent arterial reconstruction, one patient with profundaplasty and nine patients with bypass procedures. Venous blood was sampled from the antecubital vein (arm) and the femoral vein (leg) of the affected limb 1 day before and 1 month after surgery. Ten control subjects (matched according to age, sex, diabetic status, and renal insufficiency) were also sampled. Whole blood viscosity, plasma viscosity, erythrocyte aggregation tendency, and erythrocyte fluidity (the latter variable describing the deformability of the erythrocytes) were measured by means of rotational viscometry. Erythrocyte volume fraction was also determined. Fibrinogen was measured in the patients with CLI. RESULTS: Erythrocyte fluidity, blood viscosity, and erythrocyte volume fraction were lower in patients with CLI than in control subjects (P <.01, P <.01, and P <.05, respectively). No major differences between cubital and femoral vein blood were seen before or after the operation in patients with CLI or in control subjects. Successful revascularization did not influence the hemorheologic variables, except for a decrease in blood viscosity in femoral vein blood (P <.05). CONCLUSION: Hemorheologic properties was impaired in patients with CLI. Because no differences were seen between the systemic and local circulation and because no major improvement occurred 1 month after arterial reconstruction, other mechanisms besides local tissue ischemia may play a role.  (+info)

Kinetics of linear rouleaux formation studied by visual monitoring of red cell dynamic organization. (4/199)

Red blood cells (RBCs) in the presence of plasma proteins or other macromolecules may form aggregates, normally in rouleaux formations, which are dispersed with increasing blood flow. Experimental observations have suggested that the spontaneous aggregation process involves the formation of linear rouleaux (FLR) followed by formation of branched rouleaux networks. Theoretical models for the spontaneous rouleaux formation were formulated, taking into consideration that FLR may involve both "polymerization," i.e., interaction between two single RBCs (e + e) and the addition of a single RBC to the end of an existing rouleau (e + r), as well as "condensation" between two rouleaux by end-to-end addition (r + r). The present study was undertaken to experimentally examine the theoretical models and their assumptions, by visual monitoring of the spontaneous FLR (from singly dispersed RBC) in plasma, in a narrow gap flow chamber. The results validate the theoretical model, showing that FLR involves both polymerization and condensation, and that the kinetic constants for the above three types of intercellular interactions are the same, i.e., k(ee) = k(er) = k(rr) = k, and for all tested hematocrits (0.625-6%) k < 0.13 +/- 0.03 s(-1).  (+info)

Effects of swimming exercise on red blood cell rheology in trained and untrained rats. (5/199)

Red blood cell (RBC) mechanical properties were investigated after swimming exercise in trained and untrained rats. A group of rats was trained for 6 wk (60 min swimming, daily), and another group was kept sedentary. Blood samples were obtained either within 5 min or 24 h after 60 min swimming in both groups. In the untrained rats, the RBC aggregation index decreased to 2.60 +/- 0.4 immediately after exercise from a control value of 6.73 +/- 0.18 (P < 0.01), whereas it increased to 13.13 +/- 0.66 after 24 h (P < 0.01). RBC transit time through 5-microm pores increased to 3.53 +/- 0.16 ms within 5 min after the exercise from a control value of 2.19 +/- 0. 07 ms (P < 0.005). A very significant enhancement (166%) in RBC lipid peroxidation was detected only after 24 h. In the trained group, the alterations in all these parameters were attenuated; there was a slight, transient impairment in RBC deformability (transit time = 2.64 +/- 0.13 ms), and lipid peroxidation was found to be unchanged. These findings suggest that training can significantly limit the hemorheological alterations related to a given bout of exercise. Whether this effect is secondary to the training-induced reduction in the degree of metabolic and/or hormonal perturbation remains to be determined.  (+info)

Diameter changes in skeletal muscle venules during arterial pressure reduction. (6/199)

Previous studies in skeletal muscle have shown a substantial (>100%) increase in venous vascular resistance with arterial pressure reduction to 40 mmHg, but a microcirculatory study showed no significant venular diameter changes in the horizontal direction during this procedure. To examine the possibility of venular collapse in the vertical direction, a microscope was placed horizontally to view a vertically mounted rat spinotrapezius muscle preparation. We monitored the diameters of venules (mean diameter 73. 8 +/- 37.0 microm, range 13-185 microm) oriented horizontally and vertically with a video system during acute arterial pressure reduction by hemorrhage. Our analysis showed small but significant (P < 0.0001) diameter reductions of 1.0 +/- 2.5 microm and 1.8 +/- 3. 1 microm in horizontally and vertically oriented venules, respectively, upon reduction of arterial pressure from 115.0 +/- 26. 3 to 39.8 +/- 12.3 mmHg. The venular responses were not different after red blood cell aggregation was induced by Dextran 500 infusion. We conclude that diameter changes in venules over this range of arterial pressure reduction are isotropic and would likely increase venous resistance by <10%.  (+info)

Influence of erythrocyte aggregation on leukocyte margination in postcapillary venules of rat mesentery. (7/199)

The role of erythrocyte (red blood cell; RBC) aggregation in affecting leukocyte (white blood cell; WBC) margination in postcapillary venules of the mesentery (rat) was explored by direct intravital microscopy. Optical techniques were refined and applied to relate the light-scattering properties of RBCs to obtain a quantitative index of aggregate size (G), which, under idealized conditions, represents the number of RBCs per aggregate. WBC margination, defined as the radial migration of WBCs to the venular wall and their subsequent rolling along the endothelium, was measured as the percentage of the potentially maximal WBC volumetric flux within the microvessel lumen (F(WBC)(*)). In normal blood, F(WBC)(*) increased exponentially fourfold, and G increased from 1 to 1.15 as wall shear rates () were reduced from a steady-state value of approximately 600 to <100 s(-1) by proximal occlusion with a blunt microprobe. Enhancement of aggregation by infusion (iv) of dextran 500 (428 kDa), to attain a systemic concentration of 3 g/100 ml, resulted in a four- and sevenfold increase in G and F(WBC)(*), respectively, as was reduced below 100 s(-1). Inhibition of RBC aggregation by infusion of dextran 40 (37.5 kDa) caused F(WBC)(*) to fall to one-half of its steady-state level for < 100 s(-1). Thus it appears that the well-known increase of WBC margination with reductions in is strongly dependent on the occurrence of RBC aggregation. Increasing the extent of RBC aggregation during reductions in also increased the firm adhesion of WBCs to the endothelium because of an enhanced probability of contact between leukocytes and the postcapillary venular wall.  (+info)

Tk, a new colon tumor-associated antigen resulting from altered O-glycosylation. (8/199)

Erythrocyte polyagglutination antigens T and Tn are truncated O-glycan chains that are also carcinoma-associated antigens. We investigated whether Tk polyagglutination antigen could similarly be a carcinoma-associated marker and a target of immunotherapy. Monoclonal antibody LM389 was raised against Tk erythrocytes and tested by immunohistochemistry. LM389 strongly reacted with 48% human colorectal carcinomas. Labeling of normal tissues was visible on epithelial cells, mainly digestive, but was confined at a supranuclear level. Expression of the antigen on cloned human carcinoma cells correlated with sialosyl-Tn expression. O-Sialoglycoprotein endopeptidase treatment revealed that on carcinomas and cell lines, the epitope was present on O-glycans. Antibody specificity was determined using synthetic carbohydrates. Direct binding and inhibition studies indicated that LM389 best ligands were terminated by two branched N-acetylglucosamine units. Screening of murine cellular cell lines with LM389 allowed development of an experimental model with Tk-positive and -negative cells in syngeneic BDIX rats. Vaccination of rats with Tk erythrocytes provided a protection against growth of rat Tk-positive, but not of Tk-negative, tumor cells in association with the development of antibodies. Taken together, the results indicate that Tk polyagglutination antigen is a new colorectal carcinoma-associated antigen, absent from the normal cell surface, resulting from alteration of O-glycans biosynthesis and with potential as a target of immunotherapy.  (+info)

The purpose of this in vitro study was to assess the effect of 17β‐estradiol on hemorheologic parameters, namely on erythrocyte aggregation and deformability and membrane fluidity. Blood samples from 65 women (aged 57±4 years) undergoing postmenopaus
RBC aggregation is a major determinant of blood viscosity, particularly under the conditions of low shear stress, and therefore it affects blood flow dynamics mainly within the microcirculation, where such conditions prevail [9]. Experimental models and clinical studies demonstrate the potential of RBC aggregation to hinder blood flow through the microcirculation in various diseases [1]. The formation of sludge blood under these conditions is assumed to cause tissue hypoxia and acidosis, and to lead to the met- abolic disturbances. A pathogenic role for erythrocyte aggregation has been postulated in acute coronary syn- dromes [2,6]. These studies examined the blood viscosity, not the erythrocyte aggregation, which seems to be most important from our standpoint. Furthermore, we mentioned the importance of the erythrocyte aggregation for the vessels injury. Rheological disorders allow atherogenic particles to be longer exposed to the vascular endothelial and consequently greater interaction ...
Red blood cells in the Rouleau formation, coloured scanning electron micrograph (SEM). Red blood cells are often stacked together because of their shape and the way they pass through tiny capillaries. They are the most abundant type of cell in human blood, accounting for 40% of the blood volume. Each cubic millimetre of blood contains around five million of these tiny, flexible disc-shaped cells. The red colour comes from the iron-containing protein haemoglobin, which picks up oxygen in the lungs and distributes it around the body. Because the cells have no nucleus and are subjected to constant physical action, they last only four months before being destroyed and broken down. Magnification: x2,000 when shortest axis printed at 25 millimetres. - Stock Image C031/9853
The pathogenic potential of RBC aggregation within the microcirculation is dependent on the extent of RBC aggregation and the cohesive forces within the aggregate (i.e., the resistance of aggregates to shear-induced disaggregation).25 This increase of the required shear forces might have important physiological consequences, especially at the microcirculatory level, since RBC are only able to pass through small capillaries as single cells.5 However, since γmin for SCA and SCC patients were similar, differences of blood viscosity and RBC deformability between the two groups probably play a role in their unequal clinical severity.26. Although the forces required to disperse preformed RBC aggregates are elevated in SCA and SCC subjects, the extent of aggregation at stasis (i.e., AI) was lower than control in both groups; this finding contrasts with results obtained by Obiefuna et al.27 on SCA patients but is consistent with results obtained by Chien et al.2 The reasons for the discordant results ...
1. The process of red blood cell (RBC) aggregation is always associated with its counterpart: phase separation. The possibility of predicting the occurrence of a specific hemodynamic effect produced by these two processes in the living vasculature i
Purpose: Adaptive Optics Scanning Laser Ophthalmoscopy (AO-SLO) has enabled noninvasive and direct monitoring of erythrocyte aggregates in the retinal capillaries. In this study, we quantified the blood flow velocity in the parafoveal capillaries of patients with diabetic retinopathy (DR) by using the AO-SLO system prototype developed by Canon Inc.. Methods: Ten patients (mean age ± standard deviation [SD], 45.8 ± 16.7 years) diagnosed with DR at Kyoto University Hospital (8 patients with mild nonproliferative DR [NPDR], 2 patients with moderate NPDR) and 8 control subjects without any history of ocular or systemic diseases (mean age, 34.6 ± 8.6 years) were recruited for this study. AO-SLO videos were acquired from the temporal and nasal areas located 0.5° from the foveal center. The scan area of the retina was 1.4 × 2.8°, and scans were recorded for 4 seconds per area at a frame rate of 64 Hz. Erythrocyte aggregates were detected as dark tails that were darker than the vessel shadows, ...
The increase of erythrocyte aggregation by high fibrinogen levels may be an indicator of cardiovascular risk. γ′ fibrinogen variant has been considered as a possible player in enhancing aggregation. Here, we assessed, at the single-cell level, the influence of fibrinogen on erythrocyte aggregation in essenti
Blood flow partitioning at an arteriolar bifurcation could lead to spatio-temporal variations in cell-free layer formation in the upstream and downstream vessels of the bifurcation. To investigate this effect, we quantitatively analyzed characteristics of the cell-free layer in the vicinity of an arteriolar bifurcation in the rat cremaster muscle in normal physiological flow conditions. To simulate hemorheological relevance to humans, red blood cell aggregation was elevated by infusion of Dextran 500 to levels seen in humans in normal states. Spatial variations of the layer width were observed in both the parent and larger daughter vessels. A more pronounced attenuation of the layer width was generally observed in the parent vessel at its wall adjacent to the side branch than at its opposite wall. A thicker layer width was consistently found at the opposite than adjacent wall of the larger daughter vessel. Accordingly, large asymmetries of the layer widths could be developed on opposite sides of ...
Since immune responses play a major role in the development of connective tissue diseases, it is not surprising that a number of laboratory studies reflect these responses. Prior to the 1940s when rheumatoid and LE factors became widely known, one relied mainly on erythrocyte sedimentation rate and serum electrophoresis to identify protein abnormality. Elevated sedimentation rate depends on rouleaux formation, and rouleaux formation is dependent upon large asymmetric molecules of fibrinogen and gamma globulin in plasma. The demonstration of gamma globulin has become the cornerstone of the immunologists edifice. It is amazing to see how the subspecialty of immunology has mushroomed to involve the many facets of disease processes such as connective tissue diseases, skin diseases, gastrointestinal diseases, renal diseases, and cancer. More recently, immune deficiency diseases have included the pediatrician in the ever-enlarging field of immunology as has the modern-day discovery of human leukocyte antigen
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.. ...
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.. ...
Internal Medicine, State medical University, Tbilisi, Georgia. Abstract. It could be conjectured that the hemorheological disorders are involved in development of the ischemic heart disease. But this fact was so far insufficiently cleared up. The present studies were carried out in patients with various forms of chronic ischemic heart disease. We investigated the most significant factor of rheological disorders in the microcirculation, the erythrocyte aggregability, which a technique that provided us with the direct and quantitative data. Simultaneously we investigated in the some patients the tone of the resistance arteries of the hand with an original non-invasive technique. We found that the erythrocyte aggregability increased almost twice in the blood of investigated patients as compared to the healthy control group. The aggregability was positively correlated with severity of the disease. ...
I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Doctor Adikwu cured them. The fund supports a wide range of activities on behalf of crime victims, ungraciously go including victim compensation and assistance services, demonstration programs, training and technical assistance, program evaluation and replication, and programs to assist victims of terrorism and mass violence? Im surprised at how quick your blog loaded on my mobile. Und da hab ich mit Lisinopril keinerlei Probleme und halte meinen Wert bei 130/85mmHg? Closely monitor blood pressure, lady era tablet price in pakistan renal function, and electrolytes. Increased red blood cell aggregation in patients with idiopathic intracranial hypertension. Levothroid was an orally administered levothyroxine sodium drug used to treat hypothyroidism, a condition in which an individual has a thyroid deficiency. For instance, they may decide to take three, four, or even more VigRX Plus ...
Aim: This study aimed to examine the aggregation activity of basic regular blood elements of calves during the milk-feeding phase.. Study Design: The study was initiated in 39 black and white breed calves, which were examined at the ages of 11, 15, 20, 25 and 30 daysat Kolos farm in the Fatezh district of the Kursk region, Russia, in spring, 2014.. Methods: We used biochemical, haematological and statistical methods of investigation. We estimated the intensity of lipid peroxidation (LPO) in the plasma, as well as the aggregation of erythrocytes, platelets and neutrophils.. Results: It was found that the calves had an upwards trend of spontaneous erythrocyte aggregation during the milk-feeding phase. This was identified by a slight upwards trend in the total quantity of erythrocytes in an aggregate, an increase in the quantity of the aggregates themselves and a decreased number of disaggregated erythrocytes. All the calves had a trend towards an increase of platelet aggregation during the ...
View more ,Impaired heart rate variability (HRV)and haemorheology are independently associated with cardiovascular disease and diabetic complications. The aim of the present study was to investigate the relationships between parameters of HRV,and red blood cell (RBC) aggregation and deformability, in older women with type 2 diabetes. Twenty women (age 69 ᠲ yr) with uncomplicated type 2 diabetes and twenty controls (age 69 ᠳ yr) participated in the study. Beat-to-beat cardiac (RR) intervals over 5 min were analysed for HRV parameters in the time and frequency domains. Blood was sampled for RBC deformability, as well as RBC aggregation in two suspending mediums: haematocrit adjusted plasma and 3% dextran 70. RBC aggregation was increased and HRV was impaired for those with type 2 diabetes when compared with control. RBC aggregation was negatively related to low frequency power of HRV, and was positively related to high frequency power of HRV, for subjects with type 2 diabetes. RBC ...
Renée Rouleau is a celebrity esthetician with 25 years of experience. Early on, Renée recognized that every persons skin is unique; however, the skin care industry mostly relied on a one-size-fits-all approach to skin care.. So Renée began formulating her own line of products based on nine distinct skin types to ensure her clients achieved the results they desired. Healthy, beautiful and glowing skin. Welcome to Renée Rouleau.. Read more about products. ...
Renée Rouleau is a celebrity esthetician with 25 years of experience. Early on, Renée recognized that every persons skin is unique; however, the skin care industry mostly relied on a one-size-fits-all approach to skin care.. So Renée began formulating her own line of products based on nine distinct skin types to ensure her clients achieved the results they desired. Healthy, beautiful and glowing skin. Welcome to Renée Rouleau.. Read more about products. ...
An appointment at this cozy spa starts with a diagnosis: Renée Rouleau believes there are nine distinct skin types and has created regimens to care for
A Personal Message from Renée Rouleau. So, I have big news to share. (Deep breath…) After a lot of reflection, Ive made the difficult decision to close the Plano Spa, effective January 31, 2020. This may come as a surprise to all of you as our Plano spa is a thriving location for both spa services and as a retail loca
In mid-1998 the 191 distributor Hgh molecule was genetically engineered in the workplace. Since then all HGH is synthetically produced and HGH from cadavers is no mortal in use. Inductive HGH (Somatrophin) is free to us now in two forms. One is through a pricey doctors pharmaceutical prescription, and secondly at a valid toll through a homeopathic exam spray. A position therapy deciding would be Secretogogues and Stacked Radical products which take absolutely no HGH. The aim here is to cable your own body, by stimulating the Endocrine Secretor, to food many of its own HGH. Alas this latter therapy totality for only a month or two ...
Skin Correcting Serum improves acne prevention, reduces sensitivity and leaves skin healthy-looking and balanced with fewer visible blemishes and irritation.
En poursuivant votre navigation sur ce site, vous acceptez lutilisation de cookies pour vous proposer des services et offres adaptés à vos centres dintérêts. Pour en savoir plus et paramétrer les cookies, cliquez ici. ...
Nam, M. H., Dewey D. Y. Ryu, B. R. Thomas, and R. Rodriguez. 1997. Expression and secretion of fusion protein (GUS) in the suspension culture of transgenic 3DG rice cell line: Effects of osmotic pressure, buffering capacity of pH and cell aggregation on GUS expression. J. Crop Science, 39: 9 -14 ...
X. Ligneau, D. Perrin, L. Landais, J.-C. Camelin, T. P. G. Calmels, I. Berrebi-Bertrand, J.-M. Lecomte, R. Parmentier, C. Anaclet, J.-S. Lin, V. Bertaina-Anglade, C. Drieu la Rochelle, F. dAniello, A. Rouleau, F. Gbahou, J.-M. Arrang, C. R. Ganellin, H. Stark, W. Schunack and J.-C. Schwartz ...
TY - JOUR. T1 - Effect of single intravenous administration of batroxobin on erythrocyte aggregability in patients with acute-stage cerebral infarction. AU - Tanahashi, N.. AU - Fukuuchi, Y.. AU - Tomita, M.. AU - Kobari, M.. AU - Takeda, H.. AU - Yokoyama, M.. AU - Itoh, D.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - We examined the effect of defibrinogenation with batroxobin on the erythrocyte aggregability (RBC-A) in 16 patients with cerebral infarction during the acute phase (less than 72 hours after onset). Eight patients received a single intravenous administration of 10 units of batroxobin (BU), while the other 8 patients received 5 BU. The RBC-A was examined using the whole-blood erythrocyte aggregometer developed by us (Am. J. Physiol. 251, H1205-H1210, 1986) with concomitant measurement of the hematocrit, albumin:globulin ratio and concentration of fibrinogen. The RBC-A values before, and at 1,2, and 7 days after 10 BU administration were 0.154±0.017/s, 0.117±0.029/s (76% of the value before ...
Rheology - the study of the flow of matter and accompanying phenomena of real bodies deformation - in relation to blood - hemorheology. Blood viscosity - the main rheological parameter - has been studied in many research centers and among many different group of patients. The main disorders related to the hemorheological properties are: coronary insufficiency, vascular congestion, myocardial infarction, cerebral circulation disorder, Reynaud disease, ischemic limbs, diabetes, anemia, tumors. The following parameters are the main blood viscosity determinants: plasma viscosity, hematocrit, red cell deformability and erythrocytes aggregation. In hemorheological studies we used mathematical rheological models. The measurements of blood and plasma viscosity are performed by means of oscillating-rotary rheometers in order to determine the dependence of blood viscosity on the shear rate and the two components of the complex blood viscosity. Determination of blood cells aggregability and deformability ...
TY - JOUR. T1 - Measurement of blood coagulation with considering RBC aggregation through a microchip-based light transmission aggregometer. AU - Lim, Hyunjung. AU - Nam, Jeonghun. AU - Xue, Shubin. AU - Shin, Sehyun. PY - 2011. Y1 - 2011. N2 - Even though blood coagulation can be tested by various methods and techniques, the effect of RBC aggregation on blood coagulation is not fully understood. The present study monitored clot formation in a microchip-based light transmission aggregometer. Citrated blood samples with and without the addition of calcium ion solution were initially disaggregated by rotating a stirrer in the microchip. After abrupt stop of the rotating stirrer, the transmitted light intensity over time was recorded. The syllectogram (light intensity vs. time graph) manifested a rapid increase that is associated with RBC aggregation followed by a decrease that is associated with blood coagulation. The time to reach the peak point was used as a new index of coagulation time (CT) ...
Authors: Vayá, Amparo , Murado, Julián , Santaolaria, Marisa , Simó, María , Micó, Luisa , Calvo, Javier , Todolí, José , Ricart, Jose M. Article Type: Research Article Abstract: Atherothrombotic events are significant factors of mortality and morbidity in patients with systemic lupus erythematosus (SLE). The extent that rheological factors may be involved in these events in these patients has not been established. We measured the following rheological parameters in 86 patients with SLE, of whom 16 had suffered venous and/or arterial thrombotic events, and in 86 healthy controls: fibrinogen (Fbg), plasma viscosity (PV), blood viscosity at 230 s−1 both at native haematocrit (BVn 230 s−1 ) and corrected to 45% (BVc 230 s−1 ), erythrocyte aggregation at stasis (AE0 ) and at 3 s−1 (AE1 ), …aggregation time (Ta), aggregation index at 10 s (AI10 ), disaggregation threshold (γD), and erythrocyte deformability (ED). In addition glucose, total cholesterol (T-Chol), triglycerides (TG), ...
Blood passage time showed significant change with time of day, suggesting the existence of a daily rhythm of blood fluidity. The maximum value for blood passage time was after getting up in the morning (before breakfast). At that time, blood fluidity was at its worst for the day. Then, blood passage time fell gradually after breakfast and again after lunch. The value at 13:30 was the minimum. At that time, blood fluidity was the best of the day. Okazaki et al [9] reported that endurance exercise training shortened whole blood passage time with the increase in exercise amount of training by decreasing red cell count and hematocrit. Moderate exercise shortened whole blood passage time and brought good physical performance, thus indicating that short blood passage time is advantageous to the oxygen transport.. We used multiple regression analysis to try to identify the factors that determine the daily rhythm of blood fluidity. Based on multiple regression analysis, we inferred that body temperature ...
The molecular weight and aggregation tendency of a reference-soil fulvic acid in Armadale horizon Bh were determined by vapor-pressure osmometry using tetrahydrofuran and water as solvents. With tetrahydrofuran, number-average molecular weight values of 767 ?? 34 and 699 ?? 8 daltons were obtained from two separate sets of measurements. Two sets of measurements with water also yielded values within this range (754 ?? 70 daltons) provided that the fulvic acid concentration in water did not exceed 7 mg ml-1; at higher concentrations (9.1-13.7 mg ml-1) a number-average molecular weight of 956 ?? 25 daltons was resolved, providing evidence of molecular aggregation. Extension of these studies to 80% neutralized fulvic acid showed that a sizeable fraction of the sodium counter ion is not osmotically active....
This study aimed to investigate the relationship between endothelial nitric oxide synthase Glu(298)Asp gene polymorphism and hemorheological parameters. Red blood cell (RBC) deformability, aggregation were measured using an ectacytometry, whole blood, plasma viscosities were determined by a viscometer. Restriction fragment length polymorphism was used to detect polymorphism. Plasma nitrite, nitrate concentrations were determined by Griess method. The genotype distribution of the control group was as follows: 50 (67.5%) GG, 21 (28.4%) GT, 3 (4.1%) TT. A 48 (57.8%) of the patients with CAD had GG, 28 (33.7%) GT, 7 (8.5%) of them TT genotype. RBC aggregation index of CAD patients with G allele was higher and t1/2 lower compared to controls carrying the same allele. The amplitude of RBC aggregation of healthy subjects with T allele, who are under increased cardiovascular risk was lower compared to control subjects with G allele. The results of this study indicate that, alterations in RBC aggregation ...
Review for Renee Rouleau, Renee Rouleau Hydrating Mineral Toner, Toners, Astringents. Read more Renee Rouleau product reviews at Total Beauty.
Cerebral and myocardial infarctions share common aspects of pathobiochemistry. The central problem is the oxygen supply of the infarcted region. To maintain this supply, H.E.L.P.-apheresis (Heparin-mediated Extracorporeal LDL/Fibrinogen Precipitation) has already proven beneficial in the prevention and therapy of myocardial infarction. Since H.E.L.P.-apheresis can lower significantly plasma viscosity and erythrocyte aggregation without reducing the oxygen transport capacity, patients with cerebral infarction (stroke) may also benefit from our experiences in myocardial ischemia. The system is designed to remove selectively plasma fibrinogen, LDL-cholesterol and lipoprotein(a) from blood circulation, simultaneously. The removal of the plasma compounds is achieved by extracorporeal precipitation with heparin at low pH. Excess heparin is completely removed by an adsorber before the plasma is given back to the patient. H.E.L.P.-apheresis has proved to be safe in patients with coronary heart disease and
Calcium, Administration, Blood, Blood Viscosity, Calcium Dobesilate, Capillary, Capillary Permeability, Drugs, Erythrocyte, Erythrocyte Aggregation, Filtration, Patients, Permeability, Platelet, Prostaglandins, Thromboxanes, Treatment, Venous Insufficiency, Viscosity, Work
Aim: To study erythrocyte aggregation in rats with experimental model of COPD in the dynamics of phototherapy with lamps with ceramic coating.. Methods: An experimental model of COPD was reproduced in 22 white rats under the influence of tobacco smoke in a special chamber, where they were placed daily for 30-40 minutes for 2 months. Control group (11 rats) is contained in similar conditions but without exposure to tobacco smoke. For the treatment of half of the rats with experimental COPD we used the method of phototherapy with infrared light from ceramic-coated lamps with a narrow emission spectrum (wavelengths of 2-40 microns). Phototherapy on the area of lungs was carried out daily for 10 days: 5 minutes of the first 5 procedures and 10 minutes of the next 5 ones. Spontaneous aggregation of erythrocytes was quantitatively evaluated by a special system of criteria for micrographs (made by a camera connected to a microscope) of aggregates of red blood cells.. Results: In the 1st group without ...
An elevated concentration of fibrinogen in blood is a significant risk factor during many pathological diseases, as it leads to an increase in red blood cells (RBC) aggregation, resulting in hemorheological disorders. Despite the biomedical importance, the mechanisms of fibrinogen-induced RBC aggregation are still debatable. One of the discussed models is the non-specific adsorption of fibrinogen macromolecules onto the RBC membrane, leading to the cells bridging in aggregates. However, recent works point to the specific character of the interaction between fibrinogen and the RBC membrane. Fibrinogen is the major physiological ligand of glycoproteins receptors IIbIIIa (GPIIbIIIa or αIIββ3 or CD41/CD61). Inhibitors of GPIIbIIIa are widely used in clinics for the treatment of various cardiovascular diseases as antiplatelets agents preventing the platelets’ aggregation. However, the effects of GPIIbIIIa inhibition on RBC aggregation are not sufficiently well studied. The objective of
Why are most national institutes behind the times? Stanford found viruses to blame and actually cured people with antivirals. Over 20 years ago, they also found blood clumping to be the problem. As blood clumps into a rouleaux formation, it can t make it to the small capillaries very well. Numerous things cause clumping like poor GI health, radiation poisoning, and proteins leaking into circulation. Let me boldface MITOCHONDRIA for everyone and a molecule called OXYGEN. If oxygen fails to be delivered, how is mitochondria supposed to function? T ...
Spalding Orthopedic Design Specializes In Upper And Lower Extremity Prosthetics And Orthotics For Adults And Children In Rouleau, Saskatchewan.
A healthy colon looks like evenly braided muscles. On the other hand, unhealthy colons are deformed: twisted and looped in some parts, ballooned and engorged in others, as revealed by barium X-rays. Visit a colon therapist, if only to observe the pictures of unhealthy colons and see for yourself how ugly one can be on the inside.. The blood of a healthy person is also beautiful. The red blood cells are uniformly round. The blood of a body full of toxins is contaminated with pathological bacteria, abnormal proteins, and parasites. When red blood corpuscles clump together, the condition is called Rouleau or sticky blood. Rouleau, this clumpy, unattractive blood, appears 5 to 20 years before symptoms of illness present themselves. It is an early messenger of hundreds of degenerative diseases. Conglomerates of red blood cells cannot access the fine capillaries of the body. Rouleau is particularly damaging to the organs of the head, in particular the eyes, ears, and scalp. A diet high in meat and ...
Written by Keith Giffen & John Rogers Art by Cully Hamner, Duncan Rouleau, Cynthia Martin and Phil Moy Cover by Duncan Rouleau Collecting THE BLUE BEETLE #1-6! Tearing its way through the events of DAY OF VENGEANCE and INFINITE CRISIS, the mystical Blue Beetle scarab has chosen its new guardian: teenager Jaime Reyes! But supernatural powers can be a blessing or a curse, and when it comes to the powers of the Scarab, you don\t get one without the other. Advance-solicited; on sale December 27
Published in: PLOS Pathogens 2008Authors: Kevin N Couper Daniel G Blount Mark S Wilson Julius C R Hafalla Yasmine BelkaidAffiliation: London School of Hygiene Tropical Medicine National Institutes of Health Yale UniveAbout: Downregulation and upregulation Immune system Interleukin 10 TGF beta signalin ...
Structures and products of endothelial cells the cells lining blood vessels maintain blood fluidity by preventing excessive clotting and prevent bleeding by promoting clotting. The following endothelium-associated terms are presented as a guide to style. Three glycoprotein complexes are synonymous with 3 integrins and take part in hemostasis: |
Structures and products of endothelial cells the cells lining blood vessels maintain blood fluidity by preventing excessive clotting and prevent bleeding by promoting clotting. The following endothelium-associated terms are presented as a guide to style. Three glycoprotein complexes are synonymous with 3 integrins and take part in hemostasis: |
PhD v d s. Dr. T tsimon Kinga „Hemorheological investigations in carotid artery stenosis and in critically ill patients c m PhD rtekez s nek 2017. febru r 22- n (szerda) 11 rakor a PTE OK Dr. Entz B la Klinikai Oktat si K zpontj ban (P cs, Ifj s g t 13. K002 terem) tartand nyilv nos vit ja.. A Bizotts g sszet tele:. eln k:. Dr. Koll r Lajos Ph.D egyetemi tan r (PTE OK). tagok:. Dr. Arat Endre Ph.D egyetemi docens (PTE OK). Dr. Kom csi Andr s D.Sc egyetemi docens (PTE OK). opponensek:. Dr. Nagy Lajos Ph.D f igazgat f orvos (Szombathely). Dr. N meth Norbert Ph.D egyetemi docens (DE). ...
J:138147 Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA, Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet. 2008 Sep 1;17(17):2691-702 ...
After 15 years in the restaurant business, Dawn Lancaster, a 36-year-old from Groton, figured her lifelong career would be in the hospitality field. That was until 2011, when her preteen daughter.... Posted on December 21, 2016 by Michael Rouleau ...
by OConnor, C.M and Starling, R.C and Hernandez, A.F and Armstrong, P.W and Dickstein, K and Hasselblad, V and Heizer, G.M and Komajda, M and Massie, B.M and McMurray, J.J.V and Nieminen, M.S and Reist, C.J and Rouleau, J.L and Swedberg, K and Adams, K.F and Anker, S.D and Atar, D and Battler, A and Botero, R and Bohidar, N.R and Butler, J and Clausell, N and Corbalán, R and Costanzo, M.R and Dahlstrom, U and Deckelbaum, L.I and Diaz, R and Dunlap, M.E and Ezekowitz, J.A and Feldman, D and Felker, G.M and Fonarow, G.C and Gennevois, D and Gottlieb, S.S and Hill, J.A and Hollander, J.E and Howlett, J.G and Hudson, M.P and Kociol, R.D and Krum, H and Laucevicius, A and Levy, W.C and Méndez, G.F and Metra, M and Mittal, S and Oh, B.-H and Pereira, N.L and Ponikowski, P and Tang, W.H.W and Tanomsup, S and Teerlink, J.R and Triposkiadis, F and Troughton, R.W and Voors, A.A and Whellan, D.J and Zannad, F and Califf, R.M and Kardiologi and Linköpings universitet and Institutionen för medicin och ...
La micropuncture cosmétique est une technique minimalement invasive utilisant un rouleau sur lequel on retrouve de petites aiguilles de 0.2 mm qui produisent d
Machines vapeur Wilesco, Wilesco mod les, rouleaux compresseur, mod les pour machines vapeur, kits monter pour machines vapeur, locomotives vapeur
TY - JOUR. T1 - Hemorheological parameters in coronary artery disease. AU - Kesmarky, G.. AU - Toth, K.. AU - Habon, L.. AU - Vajda, G.. AU - Juricskay, I.. PY - 1998/7/1. Y1 - 1998/7/1. N2 - Hemorheological parameters are primary risk factors in ischemic heart disease (IHD). In the present study the relation of these parameters to the severity of coronary artery disease (CAD) was examined. The data of 109 patients (mean age: 55 ± 9 years) undergoing coronary angiography and 59 healthy controls (mean age: 35 ± 10 years) were analyzed. Hemorheological parameters (hematocrit, fibrinogen level, plasma viscosity (PV) and apparent whole blood Viscosity (WBV)) were determined and the circulatory index (CRI) was calculated. Patients were classified into three groups according to their coronary vessel state based on the coronary angiogram: Group 1 (n = 19, mean age: 53 ± 8 years) without significant CAD, Group 2 (n = 19, mean age: 51 ± 11 years) with single vessel disease, Group 3 (n = 71, mean age: ...
BACKGROUND: The standard preservation solution used during organ procurement and preservation of most organs is the University of Wisconsin (UW) solution. Despite its superiority over other cold storage solutions, the inclusion of hydroxyethyl starch (HES) as one of the components of the UW solution has been both advocated and denied. This study determined whether HES had any effect on red blood cell (RBC) aggregability and correlated aggregation parameters with HES molecular weight. METHODS: Human RBC aggregability and deformability were investigated in vitro, at 4 degrees C, with a laser-assisted optical rotation cell analyzer. The study of RBC aggregation in a binary HES-HES system gave an indication about the nature of HES-RBCs interactions. Bright field microscopy and atomic force microscopy were used to morphologically characterize the aggregates size and form. RESULTS: High molecular weight HES and UW solution had a potent hyperaggregating effect; low molecular weight HES had a hypoaggregating
Buy onion skin jacquard braid ladybird online from V V Rouleaux. Visit V V Rouleaux to buy ribbons and trimmings online, order samples and to get fun ideas from V V Inspire.
Methods:Whole blood viscosity at high and low shear rate (HBV,LBV),plasma viscosity (PV) and whole blood LPO were examined in 40 women with PIH and 30 normal late pregnant women. 方法随机选择妊高征患者40例(妊高征组)、正常晚期妊娠妇女30例(正常孕妇组),用硫代巴比妥酸比色法测定全血LPO水平,用粘度计测定高切、低切变率全血粘度及血浆粘度,分析血液粘度各指标与LPO水平的关系 ...
TY - JOUR. T1 - Effects of sulfhydryl inhibition on red blood cells. II. Studies in vivo.. AU - JACOB, H. S.. AU - JANDL, J. H.. PY - 1962/7. Y1 - 1962/7. UR - http://www.scopus.com/inward/record.url?scp=0002880017&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0002880017&partnerID=8YFLogxK. U2 - 10.1172/JCI104607. DO - 10.1172/JCI104607. M3 - Article. C2 - 14450645. AN - SCOPUS:0002880017. VL - 41. SP - 1514. EP - 1523. JO - Journal of Clinical Investigation. JF - Journal of Clinical Investigation. SN - 0021-9738. ER - ...
A novel computational approach to the structural analysis of ordered β-aggregation is presented and validated on three known amyloidogenic polypeptides. The strategy is based on the decomposition of the sequence into overlapping stretches and equilibrium implicit solvent molecular dynamics (MD) simulations of an oligomeric system for each stretch. The structural stability of the in-register parallel aggregates sampled in the implicit solvent runs is further evaluated using explicit water simulations for a subset of the stretches. The beta-aggregation propensity along the sequence of the Alzheimers amyloid-β peptide (Aβ42) is found to be highly heterogeneous with a maximum in the segment V12HHQKLVFFAE22 and minima at S8G9, G25S26, G29A30, and G38V39, which are turn-like segments. The simulation results suggest that these sites may play a crucial role in determining the aggregation tendency and the fibrillar structure of Aβ42. Similar findings are obtained for the human amylin, a 37-residue ...
By: Madison Gohlke, William Nunnelley, Dr. Terry Brandebourg. My research question involved developing a sample handling method that allows human point-of-care glucometer (POCG) to accurately measure circulating blood glucose concentrations in porcine blood. Pigs are an apt biomedical research model for humans, specifically regarding the development of obesity and etabolic disease. As in humans, the accurate measurement of blood glucose concentrations is critical for assessing metabolic status as pigs become progressively obese. Human POCGs are an expedient method for measuring blood glucose in research animals and in clinical practice; the handheld instruments are portable, inexpensive, and yield rapid results. However, glucose values measured by POCGs often differ from values measured by a biochemical analyzer, the accepted clinical laboratory standard. These discrepancies can be large enough to cause potential misdiagnosis, limiting the ability to track the emergence of obesity-induced ...
Launched on 2nd September 2015, the new state of the art Fitzpatrick Referrals animal hospital based in Guildford is the first of its kind in Europe and aims to change the way cancer is treated in companion animals.. Whilst this building will impress and contain the latest equipment, it is the team of people inside that makes it truly outstanding.. We have brought together world class medical and surgical oncologists with extensive experience in advanced radiation procedures, and the best nursing teams in order to gain a better understanding of animal cancer and to use that knowledge to deliver the very best treatment to animals.. We aim to deliver all of the options to all of the animals all of the time, and we aim to work with our human colleagues to better inform the treatment of cancer for everyone.. With Fitzpatrick Referrals Orthopaedics and Neurology, we will also be the only centre in Europe offering custom-designed 3D-printed limb and joint salvage prostheses.. ...
Experts **** aforesaid that of one with the early burthen release supplements or techniques, the Asiatic unaged bush could be an first-class component to your fast. An graphics thats been skilful in umteen cultures for thousands of years, firewalking is nearly mind/body translation. A comparing with a people of non-COPD patients discount nolvadex 20 mg on-line. Lowincome families are much liable to acquire cheap, unhealthy, clarified foods as anti to healthy, spontaneous foods. Because of the gamy amounts of metal initiate in fish, however, it commode be vulnerable to exhaust the number of seafood you would require in position to contact the optimum inspiration. Incidents crapper hap at sea, likewise prinivil 5 mg. Roughly grouping do arise towering material diets and approximately do not. Fortunately, when hunting for aggregation on vitamins and nutraceuticals, thither is a one-stop trustworthy whitener. I was fit to remedy my symptom course discount lipotrexate 60 caps otc ...
Study of the effect of soot aggregation on thermal radiation: application of DDA on 3D combustion soot obtained by SEM tomography. ...
A pre-determined concentration of stabilized, maturation-arrested porcine reticulocytes in a red blood cell base, useful as a reticulocyte control composition. The composition can be provided in the form of a concentrated reticulocyte composition, to be diluted to a desired final reticulocyte concentration at the time of use. The composition can also be provided in the form of a diluted, ready-to-use control composition. Also included is a method of preparing such a composition, the method involving sequential steps of forming and sedimenting Rouleaux bodies.
Los Angeles: Some of the skin care techniques that people think are helping their skin are actually doing more harm than good, says skin care expert Rene Rouleau and adds that over time these habits may harm the skin.
From Dr. Dennis Gross to Renée Rouleau, weve rounded up seven skin care lines developed by dermatologists and skin care pros that deliver legit results.
Gilbert E, Mérette C, Jomphe V, Emond C, Rouleau N, Bouchard R-, et al. Cluster analysis of cognitive deficits may mark heterogeneity in schizophrenia in terms of outcome and response to treatment. Eur Arch Psychiatry Clin Neurosci. 2014;264(4):333-43. ...
Project Leader : Dr. Guy Armand Rouleau, Centre hospitalier de l?Universit de Montr al (CHUM). For mor informations, consult :Génome Québec ...
Turcot, V. (Valérie), Rouleau, T. (Thérèse), Tsopmo, A, Germain, N. (Nathalie), Potvin, L. (Léna), Nuyt, A.-M. (Anne-Monique), & Lavoie, J.-C. (Jean-Claude). (2009). Long-term impact of an antioxidant-deficient neonatal diet on lipid and glucose metabolism. Free Radical Biology and Medicine, 47(3), 275-282. doi:10.1016/j.freeradbiomed.2009.04. ...
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY ...
Deb-Rinker, Paromita; León, Juan Andrés; Gilbert, Nicolas L.; Rouleau, Jocelyn; Andersen, Anne-Marie Nybo; Bjarnadóttir, Ragnheiður I.; Gissler, Mika; Mortensen, Laust H.; Skjaerven, Rolv; Vollset, Stein Emil; Zhang, Xun; Shah, Prakesh S.; Sauve, Reg S.; Kramer, Michael S.; Joseph, K.S. (BioMed Central, 2015-09-04) ...
Jym, Ranjan (étudiant au PhD), Anu (finissante MSc, en co-direction avec le Dr Patrick Laprise), Marie-Christine (assistante), Joris (étudiant au PhD), Amélie (assistante), Jana (étudiante au PhD, en co-direction avec le Dr Guy Poirier/Michèle Rouleau), Hélène (technicienne), Yan (assistant), Cyril (post-doc), Gilles (technicien), Julien (post-doc), Rémi (étudiant au doctorat), Marie-Michelle (étudiante à la maitrise). Absents sur la photo (Karine Drapeau, finissante MSc; Irfan Bukhari, ...
Report prepared at Wed, 13 Dec 2017 00:09:45 UTC+1000, using data obtained within AS0.6447. The report may include routes internal to AS0.6447, and may also include routes that are accepted from adjacent ASs and marked NO EXPORT. The report also does not take into account conditions local to each origin AS in terms of policy or traffic engineering requirements. As an aggregation guide, this report is a very approximate guide at best.. ...
爱词霸英语为广大英语学习爱好者提供金山词霸、在线词典、在线翻译、英语学习资料、英语歌曲、英语真题在线测试、汉语查词等服务,爱词霸英语在线查词和在线翻译频道致力于为您提供优质的在线查词及在线翻译服务
Hello we have the following unique algo aa,a,nd we would like to know if it could be interesting in Bio. Does somebody can help ...
Erythrocyte aggregation. Retrieved from "https://en.wikipedia.org/w/index.php?title=Fibrinolysis&oldid=810560507" ...
Fabry, T. L. (1 November 1987). "Mechanism of erythrocyte aggregation and sedimentation". Blood. 70 (5): 1572-1576. PMID ... As aggregation proceeds, the average diffusion constant of the aggregate population decreases. The aggregation of red blood ... The aggregations, also known as "clumping," form as an allergic reaction to certain antibiotics and not necessarily because of ... According to Smoluchowski aggregation, the kinetics of colloids is based on the assumption that each particle is surrounded by ...
Clay dispersion turned out to not be affected by plowing while soil aggregation did. erythrocyte deformability under shear. Due ... making it possible to measure the erythrocyte deformability and the orientability of the cells. In an ektacytometer erythrocyte ... The stability of soil aggregation (clumps held together by moist clay) and clay dispersion (clay separating in moist soil), the ... Westerhof, R; Buurman, P; van Griethuysen, C; Ayarza, M; Vilela, L; Zech, W (July 1999). "Aggregation studied by laser ...
... which can be discussed under the terms erythrocyte deformability and erythrocyte aggregation. Because of that, blood behaves as ... The influence of aggregation properties on the viscoelasticity diminish and the influence of red cell deformability begins to ... Bingham fluid model takes into account the aggregation of red blood cells at low shear rates. Therefore, it acts as an elastic ... Red blood cell deformation and aggregation is also coupled with flow-induced changes in the arrangement and orientation as a ...
Erythrocyte aggregation occurs at low shear rates and implies that to all vessels (with the exception of large veins) the ... effect of aggregation is irrelevant. The interior of a blood vessel includes a near-wall layer of plasma (referred to as ...
W Kadima, L Ogendal, R Bauer, [...] and P Porting: The influence of ionic strength and pH on the aggregation properties of zinc ... Webe Kadima and Dallas L. Rabenstein: A quantitative study of the complexation of cadmium in hemolyzed human erythrocytes by 1H ... W Kadima, A McPherson, M F Dunn and F.A. Jurnak: Characterization of precrystallization aggregation of canavalin by dynamic ... research on a proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes together with ...
In 1881 he described platelets as a third element in blood after the erythrocytes and leucocytes. Platelets had been described ... He demonstrated their role in clotting through aggregation and clumping with the formation of thread like structures now known ...
... increasing their electronegativity and thus reducing erythrocyte aggregation and platelet adhesiveness. Dextrans also reduce ... The antithrombotic effect of dextran is mediated through its binding of erythrocytes, platelets, and vascular endothelium, ...
... to appropriate biological entities such as erythrocytes or particles made of gelatin or latex for passive aggregation tests. ... When antibodies are used in the preparation, they are bound to the erythrocyte or particles in their Fab regions. Thus the step ... To bind antibodies to cells such as erythrocytes in advance of performing an immunological test such as a complement-fixation ...
... erythrocyte aggregation MeSH G09.188.261.454 - erythrocyte aging MeSH G09.188.261.544 - hematopoiesis MeSH G09.188.261.544.414 ... erythrocyte volume MeSH G09.188.250.313.610 - plasma volume MeSH G09.188.250.340 - erythrocyte deformability MeSH G09.188. ... erythrocyte volume MeSH G09.330.553.400.214.610 - plasma volume MeSH G09.330.553.400.280 - cardiac output MeSH G09.330.553.400. ... erythrocyte count MeSH G09.188.250.161.330.725 - reticulocyte count MeSH G09.188.250.161.595 - leukocyte count MeSH G09.188. ...
The full blood count, erythrocyte sedimentation rate and C reactive protein are normal. Synovial fluid is typically viscous, ... and an aggregation domain. There are 3 consensus sequences for N-glycosylation and 1 chondroitin sulfate substitution site. ...
... erythrocyte aggregation MeSH E01.450.375.230 - erythrocyte indices MeSH E01.450.375.300 - figlu test MeSH E01.450.375.400 - ... erythrocyte count MeSH E01.450.375.107.330.725 - reticulocyte count MeSH E01.450.375.107.595 - leukocyte count MeSH E01.450. ...
The disease results from the aggregation of erythrocytes infected by Plasmodium falciparum which have been shown to adhere to ... Infected erythrocytes express the VAR2CSA variant of P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) which allows them to ... After undergoing these changes in the liver, the parasite is then able to infect erythrocytes in the bloodstream. It can take 7 ... This is because women who are pregnant for the first time generally lack antibodies to VAR2CSA on erythrocytes that have been ...
Other related red blood cell properties can include adhesion and aggregation, which along with deformability are often classed ... Erythrocyte deformability refers to the ability of erythrocytes (red blood cells, RBC) to change shape under a given level of ... Erythrocytes/RBC may also be tested for other (related) membrane properties, including erythrocyte fragility (osmotic or ... Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration, Anesth Analg, published ...
Other related red blood cell properties can include adhesion and aggregation, which along with deformability are often classed ... Erythrocyte fragility refers to the propensity of erythrocytes (red blood cells, RBC) to hemolyse (rupture) under stress. It ... Uses of erythrocyte mechanical fragility can include diagnostic testing, calibrations to aid comparisons of hemolysis caused by ... For example, photons or radicals can induce hemolysis.Erythrocytes/RBC may also be tested for related membrane properties aside ...
... is the reversible clumping of red blood cells (RBCs) under low shear forces or at stasis. Erythrocytes ... Influence of erythrocyte aggregation on in vivo blood flow is still a controversial issue. Enhanced aggregation affects venous ... Erythrocyte sedimentation rate closely reflects the extent of aggregation, therefore can be used as a measure of aggregation. ... Erythrocyte aggregation can also be quantitated by monitoring optical properties of blood during the time course of aggregation ...
Its alpha form, also known as vitamin E, has antioxidant properties which results in the inhibition of platelet aggregation. ... Pentoxifylline is methylxanthine derivative that drives vascular dilation and increased erythrocyte flexibility, resulting in ...
This may manifest as a hemolytic activity on erythrocytes, leading to this group of toxins being called 'hemolysins'. The cell ... Besides attachment to bacterial proteins, aggregation also inactivates the toxin. This quick inactivation highlights the ...
F. necrophorum produces hemagglutinin which causes platelet aggregation that can lead to diffuse intravascular coagulation and ... erythrocyte sedimentation rate and white blood cells (notably neutrophils). Platelet count can be low or high. Liver and kidney ...
In individuals that have cold agglutinin disease, the lifespan of erythrocytes is shortened. The rate of erythrocyte production ... As a result, the blood of a host applied to a diagnostic kit causes the aggregation of the pathogenic particles due to the ... When erythrocytes are exposed to hemagglutinins (anti-A and Anti-B antibodies), those expressing antigen A or B coagulate upon ... Human erythrocytes have two main types of antigens (Antigen A and B) expressed in different combinations to give either ...
A decreased concentration of oxygen releases ATP from erythrocytes, triggering a propagated calcium wave in the endothelial ... while the P2Y12 receptor is responsible for sustained platelet aggregation through the inhibition of adenylate cyclase and a ... increased intracellular calcium levels and transient platelet aggregation, ...
Erythrocyte aggregation. සැකිල්ල:Myeloid navs. සැකිල්ල:Immune system සැකිල්ල:Nervous system physiology සැකිල්ල:Eye and ear ...
Erythrocyte flexibility is not affected by normal doses of ancrod. The rheological changes are readily maintained and the ... The substance is intended for subcutaneous injection and intravenous infusion, and indirectly inhibits aggregation, adhesion, ... nor does it produce platelet aggregation nor cause the release of ADP, ATP, potassium, or serotonin from platelets. Platelet ...
Platelet aggregation studies are optional. Serum protein electrophoresis results indicate evidence of a monoclonal spike but ... Chemistry tests include lactate dehydrogenase (LDH) levels, uric acid levels, erythrocyte sedimentation rate (ESR), kidney and ... "Differential characteristics of Waldenström macroglobulinemia according to patterns of familial aggregation". Blood. 115 (22): ...
Recent studies show that tTG may not be involved in AD as studies show it is associated with erythrocyte lysis and is a ... Such neurological diseases are characterized in part by the abnormal aggregation of proteins due to the increased activity of ...
... reduces platelet aggregation as well as fibrinogen concentration, and thus is contraindicated to patients suffering ... Piracetam has been found to diminish erythrocyte adhesion to vascular wall endothelium, making any vasospasm in the capillary ... Piracetam may facilitate the deformability of erythrocytes in capillary which is useful for cardiovascular disease. Peripheral ...
This protein may also help maintain the membrane skeleton of erythrocytes. Kindlin 3 is a cytoskeletal signalling protein ... the FERMT3 protein disrupts the ability to form clots and coagulate by preventing integrin αIIβ3-mediated platelet aggregation ...
Calamai M, Canale C, Relini A, Stefani M, Chiti F, Dobson CM (Feb 2005). "Reversal of protein aggregation provides evidence for ... Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue ... "Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase". FEBS Letters. 367 (2): 145- ... "Kinetic partitioning of protein folding and aggregation". Nature Structural Biology. 9 (2): 137-143. doi:10.1038/nsb752. PMID ...
This occurs by blocking the nucleoside transporter through which adenosine enters erythrocyte and endothelial cells. According ... Cyclic adenosine monophosphate impairs platelet aggregation and also causes arteriolar smooth muscle relaxation. Chronic ... increasing cellular cAMP levels and blocking the platelet aggregation, response to ADP) and/or cGMP. Dipyridamole inhibits the ...
The phospholipid bilayer is formed due to the aggregation of membrane lipids in aqueous solutions. Aggregation is caused by the ... Erythrocyte membrane plays a crucial role in blood clotting. In the bilayer of red blood cells is phosphatidylserine. This is ... Red blood cells, or erythrocytes, have a unique lipid composition. The bilayer of red blood cells is composed of cholesterol ...
... erythrocytes) of almost all vertebrates[4] (the exception being the fish family Channichthyidae[5]) as well as the tissues of ... Ristocetin-induced platelet aggregation. .mw-parser-output .nobold{font-weight:normal}. clotting factors:. *Prothrombin time ... "Is hemoglobin an essential structural component of human erythrocyte membranes?". J Clin Invest. 42 (4): 581-88. doi:10.1172/ ...
F. necrophorum produces hemagglutinin which causes platelet aggregation that can lead to diffuse intravascular coagulation and ... Laboratory investigations reveal signs of a bacterial infection with elevated C-reactive protein, erythrocyte sedimentation ...
Transmission electron micrograph of a microvessel showing endothelial cells, which encircle an erythrocyte (E), forming the ... which promote platelet aggregation and adhesion to the subendothelium, and thus the formation of potentially fatal thrombi. ...
The result is inhibition of platelet aggregation.[4] Nutrition[edit]. Food sources[edit]. Vitamin B6 is widely distributed in ... The three biochemical tests most widely used are the activation coefficient for the erythrocyte enzyme aspartate ...
erythrocyte differentiation. • platelet formation. • positive regulation of osteoblast proliferation. • transcription from RNA ... platelet aggregation. • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. • regulation of ... positive regulation of erythrocyte differentiation. • positive regulation of transcription from RNA polymerase II promoter. • ... regulation of primitive erythrocyte differentiation. • positive regulation of transcription, DNA-templated. • regulation of ...
positive regulation of platelet aggregation. • cellular response to cAMP. • erythrocyte development. • regulation of cell shape ... "Entrez Gene: EPB49 erythrocyte membrane protein band 4.9 (dematin)". الوسيط ,المسار=. تم تجاهله (مساعدة); الوسيط ,العنوان=. تم ... 1996). "Human erythrocyte dematin and protein 4.2 (pallidin) are ATP binding proteins". Biochemistry. 35 (9): 3001-6. PMID ... "Headpiece domain of dematin is required for the stability of the erythrocyte membrane". Proc Natl Acad Sci U S A. 99 (10): ...
"Erythrocyte Membrane Fatty Acids and Subsequent Breast Cancer: A Prospective Italian Study". Journal of the National Cancer ... "Effect of Genistein and Daidzein on Platelet Aggregation and Monocyte and Endothelial Function". British Journal of Nutrition ( ...
Atrophie blanche', localised loss of skin pigmentation due to death of erythrocytes and scarring ... It works by reducing platelet aggregation and thrombus formation. Gastrointestinal disturbances were reported as a potential ...
"18F-positron-emitting/fluorescent labeled erythrocytes allow imaging of internal hemorrhage in a murine intracranial ... aggregation *Glanzmann's thrombasthenia. *platelet storage pool deficiency *Hermansky-Pudlak syndrome. *Gray platelet syndrome ...
This leads to blood cell aggregation and increased blood viscosity which results in impaired blood flow.[12] ... or high erythrocyte turnover; in the presence of chronic renal or liver disease; after administration of high-dose vitamin C; ...
Degradation begins inside macrophages of the spleen, which remove old and damaged (senescent) erythrocytes from the circulation ... It catalyzes the oxidation and aggregation of protein, the formation of cytotoxic lipid peroxide via lipid peroxidation and ...
Erythrocyte Sedimentation Rate. Indicates the time it takes for red blood cells to move down a tube. This shows signs of ...
positive regulation of platelet aggregation. • cellular response to cAMP. • erythrocyte development. • protein complex assembly ... 1996). "Human erythrocyte dematin and protein 4.2 (pallidin) are ATP binding proteins". Biochemistry. 35 (9): 3001-6. doi: ... "Headpiece domain of dematin is required for the stability of the erythrocyte membrane". Proc Natl Acad Sci U S A. 99 (10): ...
... these metabolites act as autocrines by feeding back to promote further aggregation of their cells of origin and as paracrines ... is preferentially metabolized to its 12-keto derivative by human erythrocytes in vitro". Eicosanoids. 1 (1): 19-25. PMID ... and to inhibit platelet aggregation responses to various agents by stimulating platelets to raise their levels of Cyclic ... and neutrophil-based inflammatory responses and 12-oxo-HT may serve as a counterpoise to platelet aggregation responses ...
The phospholipid bilayer is formed due to the aggregation of membrane lipids in aqueous solutions.[4] Aggregation is caused by ... The bilayer of red blood cells is composed of cholesterol and phospholipids in equal proportions by weight.[7] Erythrocyte ... Red blood cells, or erythrocytes, have a unique lipid composition. ...
If the blood is kept at warmer temperatures, schizonts will rupture and merozoites invading erythrocytes will mistakenly give ... Ristocetin-induced platelet aggregation. .mw-parser-output .nobold{font-weight:normal}. clotting factors:. *Prothrombin time ... the buildup of acid in the sample will cause the parasitised erythrocytes to shrink and the parasite will roll up, simulating ...
Tønnesen H, Hejberg L, Frobenius S, Andersen J (1986). "Erythrocyte mean cell volume--correlation to drinking pattern in heavy ... and dividing that product by the number of erythrocytes (red blood cells) in that volume. The mean corpuscular volume is a part ...
Aggregation begins minutes after activation, and occurs as a result of turning on the GPIIb/IIIa receptor, allowing these ... From left to right: human erythrocyte, activated platelet, leukocyte.. Inhibition[edit]. The intact endothelial lining inhibits ... Third, they connect to each other through receptor bridges: aggregation.[6] Formation of this platelet plug (primary hemostasis ... Belamarich FA, Shepro D, Kien M (November 1968). "ADP is not involved in thrombin-induced aggregation of thrombocytes of a non- ...
Stimulate erythrocyte production Follicle-stimulating hormone. FSH. anterior pituitary. gonadotrope. FSH receptor → cAMP. In ... vasoconstriction, Platelet Aggregation. PeptideEdit. Name Abbreviation Tissue Cells Receptor Target Tissue Effect ...
A genetic component to the cause of UC can be hypothesized based on aggregation of UC in families, variation of prevalence ... Inflammatory markers, such as erythrocyte sedimentation rate or C-reactive protein. *Lower endoscopy to evaluate the rectum and ... erythrocyte sedimentation rate and C-reactive protein). ...
Via cell squeezing, quantum dots can be efficiently delivered without inducing aggregation, trapping material in endosomes, or ... "Band 3 modifications in Plasmodium falciparum-infected AA and CC erythrocytes assayed by autocorrelation analysis using quantum ... Vector-based methods have resulted in aggregation and endosomal sequestration of quantum dots while electroporation can damage ...
PAF is a potent activator of platelet aggregation, inflammation, and anaphylaxis. It is similar to the ubiquitous membrane ... 2005). "Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes". J. Biol. Chem. 280 (27): ... erythrocytes). However, ceramide can possibly interact with other lipids to form bigger regions called microdomains which ...
Erythrocyte aggregation is the reversible clumping of red blood cells (RBCs) under low shear forces or at stasis. Erythrocytes ... Influence of erythrocyte aggregation on in vivo blood flow is still a controversial issue. Enhanced aggregation affects venous ... Erythrocyte sedimentation rate closely reflects the extent of aggregation, therefore can be used as a measure of aggregation. ... Erythrocyte aggregation can also be quantitated by monitoring optical properties of blood during the time course of aggregation ...
1. The process of red blood cell (RBC) aggregation is always associated with its counterpart: phase separation. The possibility ... Polymicroviscometry (PMV) and erythrocyte aggregation Issue title: Red Cell Aggregation. Proceedings of the Second ... Abstract: 1.The process of red blood cell (RBC) aggregation is always associated with its counterpart: phase separation. The ...
Erythrocyte Aggregation Factor in the Plasma and Serum of Patients with Acute Lupus Erythematosus ... Erythrocyte Aggregation Factor in the Plasma and Serum of Patients with Acute Lupus Erythematosus ... Erythrocyte Aggregation Factor in the Plasma and Serum of Patients with Acute Lupus Erythematosus ... Erythrocyte Aggregation Factor in the Plasma and Serum of Patients with Acute Lupus Erythematosus ...
This paper deals with the effect of albumin and immunoglobulins on erythrocyte aggregation parameters. The study was carried ... Influence of plasma proteins on erythrocyte aggregation Issue title: Red Cell Aggregation. Proceedings of the Second ... Abstract: This paper deals with the effect of albumin and immunoglobulins on erythrocyte aggregation parameters. The study was ...
Alexander V. Priezzhev, Nikolai N. Firsov, Olga M. Ryaboshapka, and Marina G. Vyshlova "Aggregation kinetics of erythrocytes in ... Aggregation kinetics of erythrocytes in whole blood: comparison of data processing algorithms. ... Alexander V. Priezzhev, Nikolai N. Firsov, Olga M. Ryaboshapka, Marina G. Vyshlova, "Aggregation kinetics of erythrocytes in ... Samples of erythrocyte suspensions of normal and pathological blood were studied by light back-scattering technique. This ...
Aggregation of erythrocytes in the dynamics of phototherapy in rats with experimental model of COPD. Yulduzkhon Kayumova ... Aim: To study erythrocyte aggregation in rats with experimental model of COPD in the dynamics of phototherapy with lamps with ... It is by 34% less than in the 1st group (p,0,05). In both groups of COPD erythrocyte aggregation was higher than in healthy ... Spontaneous aggregation of erythrocytes was quantitatively evaluated by a special system of criteria for micrographs (made by a ...
... aggregation at 100 uM by thioflavin T fluorescence method. ... Inhibition of human erythrocytes AChE-induced amyloid beta (1 ...
ENHANCED CONCANAVALIN-A AGGLUTINATION OF TRYPSINIZED ERYTHROCYTES IS DUE TO A SPECIFIC CLASS OF AGGREGATION. ... ENHANCED CONCANAVALIN-A AGGLUTINATION OF TRYPSINIZED ERYTHROCYTES IS DUE TO A SPECIFIC CLASS OF AGGREGATION. ... ENHANCED CONCANAVALIN-A AGGLUTINATION OF TRYPSINIZED ERYTHROCYTES IS DUE TO A SPECIFIC CLASS OF AGGREGATION ...
Cell-Free Layer Formation in Small Arterioles at Pathological Levels of Erythrocyte Aggregation. ... Cell-Free Layer Formation in Small Arterioles at Pathological Levels of Erythrocyte Aggregation. Microcirculation 18 (7) : 541- ... To test our hypothesis that an elevation in the aggregation level of red blood cells found in human pathological conditions ... than normal-aggregation induction (139/sec). Conclusion: Our findings confirmed the formation of a prominent cell-free layer in ...
Ong, P.K., Namgung, B., Johnson, P.C., Kim, S. (2010-06). Effect of erythrocyte aggregation and flow rate on cell-free layer ... Effect of erythrocyte aggregation and flow rate on cell-free layer formation in arterioles. ... The rat cremaster muscle was used to visualize arteriolar flows, and the extent of aggregation was raised by dextran 500 ... such as red blood cell aggregation and flow rate. In this study, we investigate the effect of these two rheological parameters ...
OBJECTIVES: Emerging research is revealing that direct physical contact of the human body with the surface of the earth (grounding or earthing) has intriguing effects on human physiology and health, including beneficial effects on various cardiovascular risk factors. This study examined effects of 2 hours of grounding on the electrical charge (zeta potential) on red blood cells (RBCs) and the effects on the extent of RBC clumping. DESIGN/INTERVENTIONS: SUBJECTS were grounded with conductive patches on the soles of their feet and palms of their hands ...
Erythrocyte aggregation has been consistently associated with insulin resistance, central obesity and hypertension in the ... Erythrocyte aggregation and metabolic syndrome.. Research paper by Prajwal P Gyawali, Ross S RS Richards, Diane L DL Hughes, ... Erythrocyte aggregation has been consistently associated with insulin resistance, central obesity and hypertension in the ... Increased WBV has been attributed to erythrocyte aggregation which in turn is greatly influenced by other rheological ...
Low erythrocyte aggregation was significantly correlated with increased mRNA-expression of vWF (heart, liver, ileum) and P- ... Acute IHD was followed by a dramatic drop in erythrocyte aggregation and immediate prothrombotic (significant vWF mRNA ... The pathogenic potential of low erythrocyte aggregation could be important for patients undergoing on-pump cardipopulmonary ... erythrocyte aggregation (LORCA), and endothelial activation (real-time quantitative RT-PCR on von Willebrand factor (vWF), E- ...
Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows. ... Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows. ... Zhang, J., Johnson, P. C., & Popel, A. S. (2009). Effects of erythrocyte deformability and aggregation on the cell free layer ... Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows. ...
Detection of flow velocity fluctuations associated with erythrocyte aggregation in diabetic retinopathy by using adaptive ... Detection of flow velocity fluctuations associated with erythrocyte aggregation in diabetic retinopathy by using adaptive ... Detection of flow velocity fluctuations associated with erythrocyte aggregation in diabetic retinopathy by using adaptive ... Erythrocyte aggregates were detected as "dark tails" that were darker than the vessel shadows, and the velocities of all the ...
This finding was supported by a greater half time for RBC aggregation in the samples obtained 60 and 90 s after tourniquet ... In conclusion, this study revealed that RBC deformability and aggregation might be significantly altered in the samples ... The aggregation index (AI) decreased with time after tourniquet removal reaching significantly lower values than the control at ... red blood cell deformability and aggregation indices) assessed in blood samples obtained after 5, 30, 60 and 90 s following the ...
Increased erythrocyte aggregation in infectious diseases: Influences of acute phase proteins ... Friesrichs, E., Germs, J., Lakomek M., Winkler, A. H., & Tillmann, W. (1984). Increased erythrocyte aggregation in infectious ...
The aggregation is determined by sequential analysis of the He-Ne laser transmission data through erythrocyte suspension at ... The hemorheological parameters, erythrocyte aggregation and deformability are determined in leprotic patients and are compared ... The observations show that in leprosy the aggregation of erythrocyte is marginally reduced and the deformability is ... Kumaravel M, Singh M. Aggregation and deformability of erythrocytes in leprosy. Indian Journal of Experimental Biology. 1995 ...
Erythrocyte aggregation. Retrieved from "https://en.wikipedia.org/w/index.php?title=Fibrinolysis&oldid=810560507" ...
Erythrocyte aggregation (EA) is a characteristic behaviour of erythrocytes forming reversible clumps especially in vitro at low ... An optofluidic point-of-care device for quantitative investigation of erythrocyte aggregation during coagulation. dc. ... An optofluidic point-of-care device for quantitative investigation of erythrocyte aggregation during coagulation. en_US. ... In addition to revealing the relation between coagulation and aggregation, this device is promising for rapid WB coagulation ...
This dissertation investigates parameters involved in erythrocyte aggregation, methods of measuring and testing erythrocyte ... Erythrocyte Aggregation due to Surface Nanobubble Interactions During the Onset of Thermal Burn Injury. Login ... Erythrocyte Aggregation due to Surface Nanobubble Interactions During the Onset of Thermal Burn Injury. Seidner, Harrison ... The basic mechanism leading to erythrocyte aggregation at the onset of thermal injury is unknown. ...
Interaction of erythrocytes in the process of pair aggregation in blood samples from patients with arterial hypertension and ... aggregation; arterial hypertension; optical trap; manipulation of single cells; aggregation force; erythrocytes ... Interaction of erythrocytes in the process of pair aggregation in blood samples from patients with arterial hypertension and ... The study of erythrocytes interaction is important both for understanding the fundamental aggregation mechanisms and for ...
N2 - The effect of fibrinogen and sialic acid content of erythrocytes on the aggregation of erythrocytes was quantitatively ... AB - The effect of fibrinogen and sialic acid content of erythrocytes on the aggregation of erythrocytes was quantitatively ... The effect of fibrinogen and sialic acid content of erythrocytes on the aggregation of erythrocytes was quantitatively examined ... abstract = "The effect of fibrinogen and sialic acid content of erythrocytes on the aggregation of erythrocytes was ...
Erythrocyte Aggregation Rehabilitation Therapeutic High Quality Pulse Magnetic Therapy Machine Wellness Center Project ...
Imaizumi K, Imai A, Maruyama T, Shiga T. Inhibition of IgG-, F(ab)2- and myeloma protein-induced erythrocyte aggregation, by ... Inhibition of IgG-, F(ab)2- and myeloma protein-induced erythrocyte aggregation, by small IgG-fragments. In: Clinical ... Inhibition of IgG-, F(ab)2- and myeloma protein-induced erythrocyte aggregation, by small IgG-fragments. / Imaizumi, Kazuhiko ... keywords = "Erythrocyte Aggregation, IgG-fragments, Immunoglobulin, Multiple Myeloma",. author = "Kazuhiko Imaizumi and Atsuko ...
... antiplatelet aggregation, liver protection, and anti-inflammation, indicating that hederagenin may exert a protective effect on ... Erythrocyte aggregation index. Platelet aggregation rate/%. Low shear. Mid shear. High shear. Viscosity. ... antiplatelet aggregation, liver protection, and anti-inflammation, indicating that hederagenin may exert a protective effect on ... antiplatelet aggregation, liver protection, antidepression, anti-inflammation, and diuresis [4-12], indicating that hederagenin ...
Raso, S., Lo Presti, R., Siragusa, S., Napolitano, M., & Caimi, G. (2020). Plasma viscosity pattern and erythrocyte aggregation ... Raso, S, Lo Presti, R, Siragusa, S, Napolitano, M & Caimi, G 2020, Plasma viscosity pattern and erythrocyte aggregation in two ... Plasma viscosity pattern and erythrocyte aggregation in two patients with congenital afibrinogenemia. / Raso, Simona; Lo Presti ... Fingerprint Dive into the research topics of Plasma viscosity pattern and erythrocyte aggregation in two patients with ...
Front microrheology of the non-Newtonian behaviour of blood: Scaling theory of erythrocyte aggregation by aging. Soft Matter. ... Front microrheology of the non-Newtonian behaviour of blood : Scaling theory of erythrocyte aggregation by aging. / TREJO SOTO ... title = "Front microrheology of the non-Newtonian behaviour of blood: Scaling theory of erythrocyte aggregation by aging", ... Front microrheology of the non-Newtonian behaviour of blood: Scaling theory of erythrocyte aggregation by aging. ...
The degree of erythrocyte aggregation was quantified using a variable called erythrocyte percentage (EP), by using the software ... Erythrocytes tend to aggregate during an inflammatory process. Evaluation of erythrocyte adhesiveness/aggregation is currently ... A simple slide test to assess erythrocyte aggregation in acute ST-elevated myocardial infarction and acute ischemic stroke: Its ... A simple slide test to assess erythrocyte aggregation in acute ST-elevated myocardial infarction and acute ischemic stroke: Its ...
Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated ... Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte ... Erythrocytes , Humans , Hydroxymethylglutaryl CoA Reductases , Liver , Onions , Plasma , Platelet Aggregation , Rats , Rats, ... erythrocyte Na efflux channels and platelet aggregation in simvastatin (SIM) treated hypercholesterolemic rats. Forty Sprague ...
  • This study was purposed to investigate the effect of onion or beet on plasma and liver lipids , erythrocyte Na efflux channels and platelet aggregation in simvastatin (SIM) treated hypercholesterolemic rats . (bvsalud.org)
  • 1979) have found platelet aggregation induced by ultrasound at peak intensities of 16 - 32 mWcm −2 . (springer.com)
  • Platelet aggregation and activation, plasma coagulation, haemolysis, complement activation, T cell functionality and phenotype, monocyte derived macrophage functionality, and NK cell function were assessed in primary healthy volunteer samples treated with either aqueous efavirenz or efavirenz SDN. (whiterose.ac.uk)
  • Aspirin inhibits platelet aggregation by irreversible inhibition of platelet cyclooxygenase and thus inhibits the generation of thromboxane A 2 . (drugs.com)
  • It also inhibits platelet aggregation. (drugbank.ca)
  • In the absence of proteolytic cleavage, VWF multimerizes and leads to pathological platelet aggregation. (sciencemag.org)
  • 2. The activity of platelet aggregation was significantly greater in men with a genetic predisposition to essential hypertension. (portlandpress.com)
  • 3. Platelet aggregation was activated directly or indirectly by an increased sodium intake. (portlandpress.com)
  • PGI2 acts by signaling through Gs, and functions as a vasodilator, venodilator, and inhibits platelet aggregation. (pharmainfo.net)
  • Dietary effect on platelet aggregation in men with and without a family history of essential hyperte. (biomedsearch.com)
  • Improve flow properties of blood by lowering viscosity, improving erythrocyte flexibility, inhibiting platelet aggregation and thrombus formation, and suppressing leukocyte adhesion. (medscape.com)
  • It has been shown that AT inhibits smooth muscle cell proliferation and platelet aggregation and preserves endothelium-dependent relaxation via inhibition of PKC ( 14 ). (diabetesjournals.org)
  • Erythrocyte aggregation is the main determinant of blood viscosity at low shear rate. (wikipedia.org)
  • Prooxidants and adipocytokines generated in MetS alter erythrocyte morphology, decrease erythrocyte deformability and increase whole blood viscosity (WBV). (sparrho.com)
  • Due to the opposing effects of the cell free layer lubrication and the high viscosity of cell-concentrated core, the influence of aggregation is complex but the lubrication effect appears to dominate, causing the relative apparent viscosity to decrease with aggregation. (elsevier.com)
  • Zhang, J, Johnson, PC & Popel, AS 2009, ' Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows ', Microvascular Research , vol. 77, no. 3, pp. 265-272. (elsevier.com)
  • In this case report, we examine the behavior of plasma viscosity, explored at high and low shear rates, and erythrocyte aggregation in two patients with congenital afibrinogenemia, a clinical disorder firstly described in 1920 and that has an estimated incidence of 1 : 1-200 0000. (unipa.it)
  • Keeping in mind that spontaneous thrombosis (venous and arterial) has been often described in congenital afibrinogenemia, it can be hypothesized that the decrease in plasma viscosity and erythrocyte aggregation might cause a reduction of the endothelial synthesis and release of nitric oxide through the fall of the wall shear stress. (unipa.it)
  • The effect of erythrocyte aggregation on blood viscosity and microcirculatory flow is a poorly understood area of haemodynamics, especially with relevance to serious pathological conditions. (cut.ac.cy)
  • The primary determinants of blood viscosity are hematocrit, red blood cell deformability, red blood cell aggregation, and plasma viscosity. (wikipedia.org)
  • Along with erythrocyte activity, pentoxifylline also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity. (drugbank.ca)
  • The blood viscosity under low shear rates is determined by the aggregation ability of erythrocytes. (spie.org)
  • Rouleaux formation also determines Erythrocyte sedimentation rate which is a non-specific indicator of the presence of disease. (wikipedia.org)
  • Erythrocyte sedimentation rate closely reflects the extent of aggregation, therefore can be used as a measure of aggregation. (wikipedia.org)
  • Evaluation of erythrocyte adhesiveness/aggregation is currently available to the clinicians indirectly by erythrocyte sedimentation rate (ESR), but ESR correlates poorly with erythrocyte aggregation, hence a simple slide technique using citrated blood was used to evaluate erythrocyte aggregation microscopically and also by using image analysis. (who.int)
  • It can increase in parallel with erythrocyte sedimentation rate (ESR), but it is not influenced by hematocrit (anemia, polycytemia), or time to analysis. (nih.gov)
  • They occur when the plasma protein concentration is high, and, because of them, the ESR (erythrocyte sedimentation rate) is also increased. (wikipedia.org)
  • Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are markers of inflammatory conditions and have been used extensively by clinicians both in outpatient and inpatient settings. (healio.com)
  • examples include fibrinogen, which contributes to the erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP). (healio.com)
  • A three-phase suspension suitable for use as an erythrocyte sedimentation rate (ESR) control having the following three components: (1) a synthetic plasma base, (2) an aggregating agent such as a high molecular weight polymer or combination of high molecular weight polymers, and (3) chemically fixed. (google.es)
  • The control is designed to allow the user to monitor the accuracy and precision of analytical methods for determining the sedimentation rate of human erythrocytes in whole blood specimens. (google.es)
  • A rack of erythrocyte sedimentation rate (ESR) tubes. (teachengineering.org)
  • Students demonstrate the erythrocyte sedimentation rate test (ESR test) using a blood model composed of tomato juice, petroleum jelly and olive oil. (teachengineering.org)
  • The erythrocyte sedimentation rate (ESR) test is a popular clinical test and is solely based on the sedimentation principle. (teachengineering.org)
  • This method allows to register the kinetics of the formation of erythrocyte aggregates in stasis and the disruption of large and small aggregates in shear flow of aggregated blood in a Couette chamber. (spiedigitallibrary.org)
  • We suggest that the registered time dependence of the signal representing the aggregation kinetics can be approximated as a sum of exponentials with parameters T 1 and T 2 that reflect the characteristic times of linear and clump or network aggregates formation respectively. (spiedigitallibrary.org)
  • On the other hand the hyperbolic approximation of the aggregation kinetics enables to determine the characteristic constant of the whole aggregation process. (spiedigitallibrary.org)
  • Alexander V. Priezzhev , Nikolai N. Firsov , Olga M. Ryaboshapka , and Marina G. Vyshlova "Aggregation kinetics of erythrocytes in whole blood: comparison of data processing algorithms", Proc. (spiedigitallibrary.org)
  • Two-channel laser tweezers are used to measure the interaction kinetics of two erythrocytes at the initial stage of aggregation, i.e., the formation of a pair aggregate in vitro. (ssau.ru)
  • The study of erythrocytes interaction is important both for understanding the fundamental aggregation mechanisms and for evaluating the differences in kinetics and dynamics of aggregation, depending on the presence or absence of diseases that disturb the blood flow parameters and, therefore, the oxygen supply to tissues. (ssau.ru)
  • We analyse the kinetics and dynamics of pair aggregation of erythrocytes in blood samples from more than 60 patients with arterial hypertension, as well as from a group of healthy donors. (ssau.ru)
  • The results show that both kinetics and dynamics of erythrocyte aggregation are changed in the presence of the considered pathology. (ssau.ru)
  • So, an important problem of hemorheology is the determination of the durability of aggregates, their sizes, and the aggregation kinetics. (spie.org)
  • We present here the results of our study of peculiarities of the (dis)aggregation kinetics in relation to different pathologies: psoriatic arthritis, inherited hypercholesteremia, inherited homoglobinopathy, and some others. (spie.org)
  • This paper deals with the effect of albumin and immunoglobulins on erythrocyte aggregation parameters. (iospress.com)
  • We show that the parameters obtained with both exponential and hyperbolic data processing algorithms are sensitive to the concentration of erythrocytes in blood sample, mode of scattered light detection and other factors. (spiedigitallibrary.org)
  • Formation of a cell-free layer is an important dynamic feature of microcirculatory blood flow, which can be influenced by rheological parameters, such as red blood cell aggregation and flow rate. (nus.edu.sg)
  • Increased WBV has been attributed to erythrocyte aggregation which in turn is greatly influenced by other rheological parameters, including its membrane surface charge and plasma fibrinogen concentration. (sparrho.com)
  • In line with the preparation of the new Guidelines for the standardization of hemorheological measurement, we compared various blood rheological parameters (i.e., red blood cell deformability and aggregation indices) assessed in blood samples obtained after 5, 30, 60 and 90 s following the tourniquet removal and a blood sample obtained without applying a tourniquet (control sample). (bezmialem.edu.tr)
  • The hemorheological parameters, erythrocyte aggregation and deformability are determined in leprotic patients and are compared with that of healthy subjects. (who.int)
  • This dissertation investigates parameters involved in erythrocyte aggregation, methods of measuring and testing erythrocyte aggregation, and incorporates modeling based on first principles ultimately to propose a mechanism of this phenomenon. (stonybrook.edu)
  • The two hemorheological parameters examined by us showed a marked decrease in both patients, in one of whom erythrocyte aggregation was even undetectable. (unipa.it)
  • The LF dielectric relaxation was markedly affected not only by pretreatment of cells at 50 °C, which disrupts the spectrin network of erythrocytes, but also by the parameters of the AC pulses (frequency of the sine wave and repeat count of the pulses). (deepdyve.com)
  • Using atomic force microscopy (AFM), we show that the work and force necessary for erythrocyte-erythrocyte detachment is higher for patients than for healthy donors, with these parameters further increasing in both groups when higher fibrinogen concentrations are present. (rsc.org)
  • The erythrocyte deformability is determined by measurement of passage time (reciprocal of deformability) of erythrocyte suspension in PBS at hematocrit 6% through cellulose membrane. (who.int)
  • The first is the divergence between cell types: the most well-studied human erythrocyte membrane and the plasma membrane of other cells. (frontiersin.org)
  • Four major (carbonic anhydrase I, carbonic anhydrase II, peroxiredoxin VI, flavin reductase) and some minor (heat shock protein 90α, heat shock protein 70, α-enolase, peptidylprolyl cis-trans isomerase A) cytosolic proteins were found to be associated with the erythrocyte membrane in response to in vitro thermal stress. (deepdyve.com)
  • Unlike the above proteins, catalase and peroxiredoxin II were associated with membranes from unheated erythrocytes, and their content increased in the membrane following heat stress. (deepdyve.com)
  • This is a first report on the association of cytosolic catalase, α-enolase, peroxiredoxin VI, peroxiredoxin II and peptidylprolyl cis-trans isomerase A to the membrane or membrane skeleton of erythrocytes under heat stress. (deepdyve.com)
  • From these results, it is concluded that specific cytosolic proteins are translocated to the membrane in human erythrocytes exposed to heat stress and they may play a novel role as erythrocyte membrane protectors under stress by stabilizing the membrane skeleton through their interactions with skeletal proteins. (deepdyve.com)
  • Subsequently, the erythrocyte membrane becomes more resistant to deformity. (drugbank.ca)
  • To explore the possibility of absorption of lanthanides via digestive duct and their effects on the membrane structure and permeability of erythrocytes, the fine structure of erythrocyte membrane from Wistar rats, fed for 70 days of daily administration per os with 20 mg CeCl 3 /kg weight, was imaged by means of atomic force microscopy and FT-IR deconvolution spectra. (springer.com)
  • The results show that, although the erythrocytes maintain the intact shape, the change of secondary structure, aggregation and crosslinking of the protein particles of membrane surface and the enlarged lipid regions lead to the domain structure formation. (springer.com)
  • This structure might be responsible for the increasing permeability of erythrocyte membrane. (springer.com)
  • The reaction of lanthanide ions with n-doxyl stearic acids and its utilization for the ESR study on the permeability of lipid-bilayer of erythrocyte membrane to gadolinium ions, J. Inorg. (springer.com)
  • We investigated one possible mechanism of innate protection using a quantum dot technique to compare the distribution of host membrane band 3 molecules in genotypically normal (AA) to CC erythrocytes. (biologists.org)
  • In addition, the formation of aberrant knobs on the surface of parasitized CC erythrocytes suggests an abnormal membrane remodeling process. (biologists.org)
  • Intracellular denaturation of Hb can cause significant changes in the erythrocyte membrane. (biologists.org)
  • In sickle cell disease, the instability of HbS results in premature senescence of erythrocytes, as suggested by increased amounts of membrane-bound autologous IgG ( Bosman, 2004 ). (biologists.org)
  • Concentrated erythrocyte (i.e., red blood cell) suspensions flowing in microchannels have been simulated with an immersed-boundary lattice Boltzmann algorithm, to examine the cell layer development process and the effects of cell deformability and aggregation on hemodynamic and hemorheological behaviors. (elsevier.com)
  • We found that the cell free layer thickness increases with both cell deformability and aggregation strength. (elsevier.com)
  • In conclusion, this study revealed that RBC deformability and aggregation might be significantly altered in the samples obtained after the application and removal of a tourniquet, as a part of the blood sampling procedure. (bezmialem.edu.tr)
  • Aim: To study erythrocyte aggregation in rats with experimental model of COPD in the dynamics of phototherapy with lamps with ceramic coating. (ersjournals.com)
  • Aims: (1) To study erythrocyte aggregation/adhesiveness by a simple slide test in subjects with acute ST-elevated myocardial infarction (STEMI), acute ischemic stroke and healthy controls. (who.int)
  • IMSEAR at SEARO: Aggregation and deformability of erythrocytes in leprosy. (who.int)
  • IMSEAR at SEARO: A simple slide test to assess erythrocyte aggregation in acute ST-elevated myocardial infarction and acute ischemic stroke: Its prognostic significance. (who.int)
  • Red Cell Aggregation. (iospress.com)
  • Our results show that cell-free layer formation in the arterioles is enhanced by a combination of flow reduction and red blood cell aggregation. (nus.edu.sg)
  • The role of oxidized albumin in blood cell aggregation disturbance in burn disease. (semanticscholar.org)
  • The rat cremaster muscle was used to visualize arteriolar flows, and the extent of aggregation was raised by dextran 500 infusion to levels seen in normal human blood. (nus.edu.sg)
  • RBCs were suspended in Dextran and phosphate buffer saline solutions for the control of aggregation. (cut.ac.cy)
  • Erythrocyte: A systems model of the control of aggregation and deformability. (wpinstitute.org)
  • Erythrocyte aggregation also affects hemodynamic mechanisms in microcirculation and vascular control mechanisms. (wikipedia.org)
  • OBJECTIVES: The essential role of erythrocytes as oxygen carriers is historically well established, but their function to aggregate and the consequences on the microcirculation is under debate. (ox.ac.uk)
  • Red Blood Cell (RBC) aggregation is an important hemorheological phenomenon especially in microcirculation. (stonybrook.edu)
  • CONCLUSIONS: These results suggest that low erythrocyte aggregation might trigger endothelium-dependent thrombogenic and proinflammatory response during acute isovolemic hemodilution. (ox.ac.uk)
  • On the contrary, in the bulk flow region large aggregates occurred in regions of low velocity and high erythrocyte concentration suggesting a combined effect of hematocrit and velocity distributions on local aggregation characteristics. (cut.ac.cy)
  • This mechanism is also known as "chemiosmotic hypothesis" for aggregation. (wikipedia.org)
  • The basic mechanism leading to erythrocyte aggregation at the onset of thermal injury is unknown. (stonybrook.edu)
  • The presence or increased concentrations of acute phase proteins, particularly fibrinogen, results in enhanced erythrocyte aggregation. (wikipedia.org)
  • The effect of fibrinogen and sialic acid content of erythrocytes on the aggregation of erythrocytes was quantitatively examined by using a rheoscope combined with a television image analyzer and a computer. (elsevier.com)
  • 2) The aggregation of erythrocytes was accelerated by increasing fibrinogen concentration in the medium (due to the increased bridging force among erythrocytes) or by decreasing the sialic acid content (due to the reduction of the electrostatic repulsive force among erythrocytes). (elsevier.com)
  • 4) The contribution of the bridging force of fibrinogen to the erythrocyte aggregation was much greater than that of the electrostatic repulsive force produced by sialic acid on the surface of erythrocytes. (elsevier.com)
  • He observed that the rate at which blood settled varied among different individuals, that blood with smaller amounts of erythrocytes settled more quickly, and that the rate of settling depended on plasma fibrinogen levels. (healio.com)
  • The increase of erythrocyte aggregation by high fibrinogen levels may be an indicator of cardiovascular risk. (rsc.org)
  • γ′ fibrinogen variant has been considered as a possible player in enhancing aggregation. (rsc.org)
  • Here, we assessed, at the single-cell level, the influence of fibrinogen on erythrocyte aggregation in essential arterial hypertension. (rsc.org)
  • This can be associated with changes in blood flow, due to transient bridging of two erythrocytes by fibrinogen, representing an important cardiovascular risk factor. (rsc.org)
  • Erythrocyte aggregation (EA) is a characteristic behaviour of erythrocytes forming reversible clumps especially in vitro at low shear rates. (bilkent.edu.tr)
  • The growth of Plasmodium falciparum is abnormal in homozygous CC erythrocytes in vitro, and CC individuals show innate protection against severe P. falciparum malaria. (biologists.org)
  • We found that the accessibility of an intracellular band 3 epitope to antibody was markedly reduced in CC compared to AA erythrocytes, indicating a high degree of band 3 clustering in CC erythrocytes in vivo and during intracellular parasite development in vitro. (biologists.org)
  • Erythrocyte aggregation is determined by both suspending phase (blood plasma) and cellular properties. (wikipedia.org)
  • The hypoxic oxidative stress (plasma malondialdehyde, ex vivo oxygen radicals production in heart, lung, kidney, liver, and ileum tissue biopsies), erythrocyte aggregation (LORCA), and endothelial activation (real-time quantitative RT-PCR on von Willebrand factor (vWF), E- and P-selectins, endothelial nitric oxide synthase gene-expression in tissue biopsies) were investigated. (ox.ac.uk)
  • The velocity of non-immune erythrocyte aggregation was determined by means of an automated rheoscope, consisted of an inverted microscope, a cone-plate viscometer, a TV image analyzer and a computer, in autologous plasma at a shear rate of 7.5/sec. (elsevier.com)
  • As increasing the concentration of IgG and F(ab') 2 added to diluted plasma, the velocity of aggregation increased, resembling the accelerated aggregation in 5 cases of multiple myeloma. (elsevier.com)
  • Scoliosis correction at children of 7-8 years within 6 months by means of occupations by swimming authentically strengthened antioxidant security of erythrocytes and reduced lipid peroxidation in erythrocytes and blood plasma, considerably having improved indicators of cytoarchitecture and aggregation of erythrocytes, without having brought them, however, to level of children from control group. (rudn.ru)
  • Erythrocyte aggregation is influenced by the surface charge of red cells and the dielectric constant of the surrounding plasma, with the latter depending on the concentration and symmetry of plasma proteins. (healio.com)
  • Low erythrocyte aggregation was significantly correlated with increased mRNA-expression of vWF (heart, liver, ileum) and P-selectin (lungs, ileum, and heart). (ox.ac.uk)
  • The aggregation index (AI) decreased with time after tourniquet removal reaching significantly lower values than the control at 90 s after tourniquet removal. (bezmialem.edu.tr)
  • The observations show that in leprosy the aggregation of erythrocyte is marginally reduced and the deformability is significantly increased. (who.int)
  • Further, average cluster size (500 nm) in uninfected (native) CC erythrocytes was comparable with that of parasitized AA erythrocytes but was significantly larger (1 μm) in parasitized CC erythrocytes. (biologists.org)
  • Dipyridamole inhibits the uptake of adenosine into platelets, endothelial cells, and erythrocytes. (drugs.com)
  • Pentoxifylline inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte cAMP activity. (drugbank.ca)
  • The output signal proportional to backscattered light intensity was processed by different algorithms to quantitatively determine the aggregational properties of erythrocytes. (spiedigitallibrary.org)
  • Spontaneous aggregation of erythrocytes was quantitatively evaluated by a special system of criteria for micrographs (made by a camera connected to a microscope) of aggregates of red blood cells. (ersjournals.com)
  • 1.The process of red blood cell (RBC) aggregation is always associated with its counterpart: phase separation. (iospress.com)
  • Considering the vascular endothelium sensitivity to variations in blood rheology, the authors hypothesize that low erythrocyte aggregation will be responsible for activation of vascular endothelium during acute IHD. (ox.ac.uk)
  • Adaptive Optics Scanning Laser Ophthalmoscopy (AO-SLO) has enabled noninvasive and direct monitoring of erythrocyte aggregates in the retinal capillaries. (arvojournals.org)
  • Erythrocyte aggregates were detected as "dark tails" that were darker than the vessel shadows, and the velocities of all the dark tails observed in both temporal and nasal areas were measured. (arvojournals.org)
  • Their aggregation is known to occur during a variety of environmental, pathological, and physiological conditions and is reversible when aggregates are subject to the relatively high shear forces in the circulation. (stonybrook.edu)
  • Whether band 3 aggregates contribute to the malaria-protective effect of CC erythrocytes has not been determined. (biologists.org)
  • A hallmark of thrombotic thrombocytopenic purpura (TTP) is destruction of platelets and erythrocytes. (sciencemag.org)
  • Samples of erythrocyte suspensions of normal and pathological blood were studied by light back-scattering technique. (spiedigitallibrary.org)
  • Neurodegenerative diseases share several common pathological characteristics, including the aberrant aggregation of misfolded proteins, leading to the formation of abnormal protein inclusions [ 1 ]. (hindawi.com)
  • Surface properties of erythrocytes, such as surface charge density strongly influence the extent and time course of aggregation. (wikipedia.org)
  • Influence of erythrocyte aggregation on in vivo blood flow is still a controversial issue. (wikipedia.org)
  • The studies have shown, that under the influence of the Saransk's tap water with the high concentration of the fluoride, iron, calcium and magnesium ions (experience 3) in the pregnant albino rats' blood as compared with the non-pregnant animals (experience 2) there is the increase in the number of erythrocytes by 20. (thefreedictionary.com)
  • Gokhale, Sadashiv 2013-06-18 00:00:00 The influence of thermal stress on the association between human erythrocyte membranes and cytosolic proteins was studied by exposing erythrocyte suspensions and whole blood to different elevated temperatures. (deepdyve.com)
  • The influence of thermal stress on the association between human erythrocyte membranes and cytosolic proteins was studied by exposing erythrocyte suspensions and whole blood to different elevated temperatures. (deepdyve.com)
  • Explain that the mass, size and shape of erythrocytes influence the ESR value. (teachengineering.org)
  • This model involves the inhibition of hemozoin biocrystallization in Heme Detoxification pathway, which facilitates the aggregation of cytotoxic heme. (musicaenlamochila.net)
  • In addition to revealing the relation between coagulation and aggregation, this device is promising for rapid WB coagulation time measurement. (bilkent.edu.tr)
  • It functions as a potent Vasoconstrictor and is a promoter of platelet adhesion and aggregation. (pharmainfo.net)
  • Erythrocyte aggregation is the reversible clumping of red blood cells (RBCs) under low shear forces or at stasis. (wikipedia.org)
  • Rouleaux are stacks of erythrocytes which form because of the unique discoid shape of the cells in vertebrate body. (wikipedia.org)
  • The aggregation among cells is modeled by a Morse potential. (elsevier.com)
  • Rouleaux (singular is rouleau) are stacks or aggregations of red blood cells (RBCs) that form because of the unique discoid shape of the cells in vertebrates. (wikipedia.org)
  • The aggregation of red blood cells progresses in the same manner except that cells are biconcave rather than spherical. (wikipedia.org)
  • In the present study an experimental system involving simple brightfield microscopy has been successfully developed for simultaneous, time-resolved quantification of velocity fields and local aggregation of human red blood cells (RBC) in microchannels. (cut.ac.cy)
  • They further hypothesized that iron from the erythrocytes accumulates in the kidney cells, where it triggers the formation of reactive oxygen species, the first step in oxidative damage. (thefreedictionary.com)
  • Human erythrocytes are highly specialized enucleate cells that are involved in providing efficient gas transport. (wpinstitute.org)
  • Red blood cells have unique mechanical behavior, which can be discussed under the terms erythrocyte deformability and erythrocyte aggregation. (wikipedia.org)
  • Erythrocyte-aggregation is another mode of immune evasion where erythrocyte-covered spirochaetes avoid contact with the immune cells. (europa.eu)
  • Cell pellets were formed from horse erythrocyte suspensions by centrifugation and were subjected to intense AC pulses. (deepdyve.com)
  • Aggregation and gel formation of proteins after combined pressure-temperature treatment (L. Smeller, F. Meersman, J. Fidy, K. Heremans). (elsevier.com)
  • According to the strain, these pathogens can colonise internal organs like the brain, kidney, liver or spleen, causing emboli and haemorrhagic lesions in tissue capillaries by erythrocyte-aggregation. (europa.eu)
  • Rouleaux (singular is rouleau) are stacks or aggregations of erythrocytes. (sciencephoto.com)
  • The results of this study showed that using multiple methods for aggregation quantification, albeit empirical, could help towards a robust characterisation of the structural properties of the fluid. (cut.ac.cy)
  • The technique permits 3D reconstruction and quantification from a z-stack series of undistorted erythrocytes without fluorescence intensity loss caused by photobleaching. (biologists.org)
  • Membranes and cytosolic proteins from unheated and heat-stressed erythrocytes were analyzed by electrophoresis, followed by mass spectrometric identification. (deepdyve.com)
  • The ability of A7 to induce aggregation of ST3 was confirmed by fluorescence microscopy and flow cytometry: A7 induced aggregation of ST3, and in the presence of a complement source, A7 promoted deposition of complement component 3 (C3) on aggregated bacteria in a dose-dependent fashion. (asm.org)
  • Here, we present the results of single-cell studies of total fluorescence intensity and distribution of band 3 in uninfected and infected erythrocytes using power spectra and 1D autocorrelation analyses. (biologists.org)
  • In both groups of COPD erythrocyte aggregation was higher than in healthy rats (6,4±0,75). (ersjournals.com)
  • Conclusion: Erythrocyte aggregation increases in rats with experimental model of COPD. (ersjournals.com)
  • We used baseline data from a convenience sample of 476 adults (291 women, 185 men) participating in clinical trials at our Centre to explore relationships between erythrocyte levels of LC n -3 PUFA (a reliable indicator of habitual intake) and measures of adiposity, viz. (mdpi.com)
  • These diseases are also frequently classified as protein conformational disorders in which protein aggregation occurs due to the exposure of hydrophobic regions [ 2 ]. (hindawi.com)
  • on contrary, they inhibited the aggregation induced by IgG or F(ab') 2 as well as in multiple myeloma. (elsevier.com)
  • Conclusion: EAAT is a simple bedside test for erythrocyte aggregation, which indirectly reveals the presence and proportion of inflammation. (who.int)
  • Local aggregation characteristics were investigated at bulk and local levels using statistical and edge-detection image processing techniques. (cut.ac.cy)
  • As aggregation proceeds, the average diffusion constant of the aggregate population decreases. (wikipedia.org)
  • Enhanced aggregation affects venous hemodynamics. (wikipedia.org)
  • Tb 3+ binding to human erythrocyte spectrin resulting in conformation change and aggregation, J. Inorg. (springer.com)
  • Acute IHD was followed by a dramatic drop in erythrocyte aggregation and immediate prothrombotic (significant vWF mRNA upregulation in heart, lungs, kidney, liver, ileum) and proinflammatory (significant E- and P-selectins mRNA upregulation in lungs and ileum) endothelial activation. (ox.ac.uk)
  • The statistical data have shown that hederagenin exhibits multiple pharmacological activities in the treatment of hyperlipidemia, antiplatelet aggregation, liver protection, and anti-inflammation, indicating that hederagenin may exert a protective effect on vascular walls by improving lipid metabolism disorders and lipid deposition. (hindawi.com)
  • The molecular stability of hemoglobin is critical for normal erythrocyte functions, including oxygen transport. (biologists.org)
  • The level of aggregation was found to strongly correlate with local variations in velocity in both the bulk flow and wall regions. (cut.ac.cy)