Erectile dysfunction. Medical search

The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.

The state of the PENIS when the erectile tissue becomes filled or swollen (tumid) with BLOOD and causes the penis to become rigid and elevated. It is a complex process involving CENTRAL NERVOUS SYSTEM; PERIPHERAL NERVOUS SYSTEMS; HORMONES; SMOOTH MUSCLES; and vascular functions.

Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.

The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.

Compounds that specifically inhibit PHOSPHODIESTERASE 5.

Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.

A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.

Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.

A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.

Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.

A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.

A potent vasodilator agent that increases peripheral blood flow.

Disturbances in sexual desire and the psychophysiologic changes that characterize the sexual response cycle and cause marked distress and interpersonal difficulty. (APA, DSM-IV, 1994)

Physiological disturbances in normal sexual performance in either the male or the female.

A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.

The psychic drive or energy associated with sexual instinct in the broad sense (pleasure and love-object seeking). It may also connote the psychic energy associated with instincts in general that motivate behavior.

Drugs used in the treatment of urogenital conditions and diseases such as URINARY INCONTINENCE; PROSTATIC HYPERPLASIA; and ERECTILE DYSFUNCTION.

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.

A mixture of the mesylates (methane sulfonates) of DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and the alpha- and beta-isomers of DIHYDROERGOCRYPTINE. The substance produces a generalized peripheral vasodilation and a fall in arterial pressure and has been used to treat symptoms of mild to moderate impairment of mental function in the elderly.

Drugs used to cause dilation of the blood vessels.

The sexual union of a male and a female, a term used for human only.

Advice and support given to individuals to help them understand and resolve their sexual adjustment problems. It excludes treatment for PSYCHOSEXUAL DISORDERS or PSYCHOSEXUAL DYSFUNCTION.

Pathological processes of the URINARY TRACT in both males and females.

Enzymes that catalyze the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate.

The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.

A plant genus of the family FABACEAE that contains butrin and isobutrin.

A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.

Introduction of substances into the body using a needle and syringe.

A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.

Readiness to think or respond in a predetermined way when confronted with a problem or stimulus situation.

The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.

The emission of SEMEN and seminal fluid during the act of preparation for sexual intercourse, i.e. before there is penetration, or shortly after penetration.

A plant genus of the family ZYGOPHYLLACEAE. Members contain steroidal saponins. Ingestion by grazing animals causes PHOTOSENSITIVITY DISORDERS called geeldikkop (yellow thick head) in South Africa.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

A plant genus of the family BERBERIDACEAE which is used in DRUGS, CHINESE HERBAL. Members contain flavonol glycosides including epimedins, icariin and noricariin.

Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).

Pathological processes involving the PENIS or its component tissues.

The climax of sexual excitement in either humans or animals.

The degree to which the individual regards the health care service or product or the manner in which it is delivered by the provider as useful, effective, or beneficial.

A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.

Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.

A plant genus of the family ASTERACEAE.

A plant genus of the family BALANOPHORACEAE. Members contain stigmastanes and ursanes (TRITERPENES) and lignan glucopyranosides (LIGNANS).

Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).

Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.

The concept covering the physical and mental conditions of men.

A plant genus of the family BRASSICACEAE growing in Peru mountains. It is the source of maca root.

A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in NERVE TISSUE.

Lower urinary tract symptom, such as slow urinary stream, associated with PROSTATIC HYPERPLASIA in older men.

Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.

Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)

An araliaceous genus of plants that contains a number of pharmacologically active agents used as stimulants, sedatives, and tonics, especially in traditional medicine. Sometimes confused with Siberian ginseng (ELEUTHEROCOCCUS).

The state of being a eunuch, a male without TESTES or whose testes failed to develop. It is characterized by the lack of mature male GERM CELLS and TESTICULAR HORMONES.

Comparison of the 5-year outcome and morbidity of three-dimensional conformal radiotherapy versus transperineal permanent iodine-125 implantation for early-stage prostatic cancer. (1/997)

PURPOSE: To compare the prostate-specific antigen (PSA) relapse-free survival outcome and incidence of late toxicity for patients with early-stage prostate cancer treated at a single institution with either three-dimensional conformal radiotherapy (3D-CRT) or transperineal permanent implantation (TPI) with iodine-125 seeds. MATERIALS AND METHODS: Patients with favorable-risk prostate cancer, defined as a pretreatment PSA of less than or equal to 10.0 ng/mL, Gleason score of 6 or lower, and stage less than or equal to T2b, were selected for this analysis. Between 1989 and 1996, 137 such patients were treated with 3D-CRT and 145 with TPI. The median ages of the 3D-CRT and TPI groups were 68 years and 64 years, respectively. The median dose of 3D-CRT was 70.2 Gy, and the median implant dose was 150 Gy. Prostate-specific antigen relapse was defined according to the American Society of Therapeutic Radiation Oncology Consensus Statement, and toxicity was graded according to the Radiation Therapy Oncology Group morbidity scoring scale. The median follow-up times for the 3D-CRT and TPI groups were 36 and 24 months, respectively. RESULTS: Eleven patients (8%) in the 3D-CRT group and 12 patients (8%) in the TPI group developed a biochemical relapse. The 5-year PSA relapse-free survival rates for the 3D-CRT and the TPI groups were 88% and 82%, respectively (P = .09). Protracted grade 2 urinary symptoms were more prevalent among patients treated with TPI compared with 3D-CRT. Grade 2 urinary toxicity, which was manifest after the implant and persisted for more than 1 year after this procedure, was observed in 45 patients (31%) in the TPI group. In these 45 patients, the median duration of grade 2 urinary symptoms was 23 months (range, 12 to 70 months). On the other hand, acute grade 2 urinary symptoms resolved within 4 to 6 weeks after completion of 3D-CRT, and the 5-year actuarial likelihood of late grade 2 urinary toxicity for the 3D-CRT group was only 8%. The 5-year actuarial likelihood of developing a urethral stricture (grade 3 urinary toxicity) for the 3D-CRT and TPI groups was 2% and 12%, respectively (P<.0002). Of 45 patients who developed grade 2 or higher urinary toxicity after TPI, the likelihood of resolution or significant improvement of these symptoms at 36 months from onset was 59%. The 5-year likelihood of grade 2 late rectal toxicity for the 3D-CRT and TPI patients was similar (6% and 11%, respectively; P = .97). No patient in either group developed grade 3 or higher late rectal toxicity. The 5-year likelihood of posttreatment erectile dysfunction among patients who were initially potent before therapy was 43% for the 3D-CRT group and 53% for the TPI group (P = .52). CONCLUSION: Both 3D-CRT and TPI are associated with an excellent PSA outcome for patients with early-stage prostate cancer. Urinary toxicities are more prevalent for the TPI group and subsequently resolve or improve in most patients. In addition to evaluating long-term follow-up, future comparisons will require detailed quality-of-life assessments to further determine the impact of these toxicities on the overall well-being and quality of life of the individual patient. (+info)

Determination of intrapenial blood volume using 99mTc-labeled autologous red blood cells. (2/997)

In 17 impotent patients, radioisotope penography was performed using 99mTc-red blood cells (the patient's own red blood cells labeled with 99mTc) for the quantitative analysis of intrapenial blood volume. A visual sexual stimulation (VSS) was given to the patient after injecting the 99mTc-red blood cells. Patients showing a complete erection had their intrapenial blood volumes 4.2-11.2 times greater than before VSS (mean increase, 8.0 times). In cases of incomplete erection after VSS the intrapenial blood volumes were 3.3-7.0 times greater than before VSS (mean increase, 4.9 times). In cases showing a gentle rise in their penogram curves without evidence of an erection, intrapenial blood volumes after VSS were 2.0-3.3 times those before VSS (mean increaae, 2.9 times). By contrast, in cases showing no response to the VSS or no rise in penogram curve, post-VSS increases in intrapenial pool of blood were very slight, slight, only 1.4-1.7 times the original volume of blood. (+info)

Sexual functioning among stroke patients and their spouses. (3/997)

BACKGROUND AND PURPOSE: The aim of this study was to assess effects of stroke on sexual functioning of stroke patients and their spouses and to study the associations of clinical and psychosocial factors with poststroke changes in sexual functions. METHODS: One hundred ninety-two stroke patients and 94 spouses participating in stroke adjustment courses sponsored by the Finnish Stroke and Aphasia Federation completed a self-administered questionnaire concerning their prestroke and poststroke sexual functions and habits. The main outcome measures were (1) libido, (2) coital frequency, (3) sexual arousal, including erectile and orgastic ability and vaginal lubrication, and (4) sexual satisfaction. RESULTS: A majority of the stroke patients reported a marked decline in all the measured sexual functions, ie, libido, coital frequency, erectile and orgastic ability, and vaginal lubrication, as well as in their sexual satisfaction. The most important explanatory factors for these changes were the general attitude toward sexuality (odds ratio [OR] range, 7.4 to 21.9; logistic regression analysis), fear of impotence (OR, 6.1), inability to discuss sexuality (OR range, 6.8 to 18.5), unwillingness to participate in sexual activity (OR range, 3.1 to 5. 4), and the degree of functional disability (OR range, 3.2 to 5.0). The spouses also reported a significant decline in their libido, sexual activity, and sexual satisfaction as a consequence of stroke. CONCLUSIONS: Sexual dysfunction and dissatisfaction with sexual life are common in both male and female stroke patients and in their spouses. Psychological and social factors seem to exert a strong impact on sexual functioning and the quality of sexual life after stroke. (+info)

Health economics and sexual dysfunction. Based on a presentation by Cyril F. Chang, PhD. (4/997)

Erectile dysfunction (ED) and the results of its treatment are two separate issues, centering on how outcomes of the disorder affect the economy and the impact its treatment has on quality of life. The treatment of ED has been an $800-million-a-year business in the United States alone. The recent introduction of the drug sildenafil raises the possibility that revenues from its sale could reap billions of dollars for the pharmaceutical industry, with much of that cost being borne by the managed care industry. The introduction of sildenatil raises new cost-effectiveness concerns about all available treatment options. Both the National Institutes of Health and the American Urological Association have identified the need for better studies whose outcomes could be used to analyze the problem of ED. (+info)

Managed care and sexual dysfunction. Based on a presentation by William Parham, MD. (5/997)

The availability of managed care benefits for the treatment of sexual dysfunction is inextricably linked with cost. An atypically low increase of 4.4% in aggregate healthcare expenditures in 1995-1996 stands in sharp contrast to outlays of more than 11% between 1966 and 1993. Between 1993 and 1996, that increase hovered at about 5%, the result largely of the growth of managed care and low levels of general inflation. However, despite relative containment of overall healthcare expenditures, those related to pharmaceuticals have risen more than 9.2% annually, an increase that reflects the managed care industry's failure to restrain drug costs. In deciding whether it will cover a particular treatment, the managed care industry applies three sets of criteria relating to efficacy, medical necessity, and appropriateness. Managed care companies are expected to counter runaway pharmacy costs for sildenafil by excluding it from coverage, imposing significant limitations, or requiring higher copayments. (+info)

Secondary infertility as early symptom in a man with multiple endocrine neoplasia-type 1. (6/997)

Multiple endocrine neoplasia-type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by parathyroid hyperplasia, pancreatic endocrine tumours and pituitary adenomas. Here, we report a patient with a history of insulinoma who developed secondary infertility as a further symptom of the disease. When he was first examined at the age of 36 years, he complained of weakness, reduced libido and impotence. Laboratory evaluation revealed non-obstructive azoospermia and hyperprolactinaemia. In contrast to sexual activity and serum prolactin, semen quality did not significantly respond to bromocriptine therapy. During follow-up, a growing pituitary adenoma caused acromegaly with elevated serum concentrations of growth hormone, insulin-like growth factor 1 (IGF-1), and prolactin. After microsurgery of the tumour at the age of 44 years, sperm concentration persistently increased up to 5.6 x 10(6)/ml. In accordance with the clinical diagnosis of MEN1, DNA sequencing revealed a mutation in exon 2 of the menin gene which results in a truncated, inactive protein product. In conclusion, MEN1 with pituitary lesions may cause severe hypogonadism and infertility. Both hyperprolactinaemia and overproduction of growth hormone and IGF-1 seem to be involved in testicular dysfunction in the present case. The possible role of menin in the testis, however, remains to be elucidated. (+info)

Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence. (7/997)

We designed and evaluated a new class of molecules, nitrosylated alpha-adrenergic receptor antagonists, as potential agents for the treatment of impotence. In in vitro studies with human and rabbit corpus cavernosum strips in organ chambers, the alpha-adrenergic receptor antagonists (alpha-ARAs) moxisylyte and yohimbine and their corresponding nitrosylated compounds, SNO-moxisylyte (NMI-221) and SNO-yohimbine (NMI-187), concentration-dependently relaxed endothelin-induced contraction. The nitrosylated compounds were significantly more potent than the parent alpha-ARA. In human tissues, the specific phosphodiesterase type 5 inhibitor zaprinast potentiated the relaxing effects of the nitrosylated compounds. Only nitrosylated compounds induced accumulation of cyclic GMP in rabbit corpus cavernosum strips. Yohimbine and NMI-187 demonstrated a potent alpha2-blocking activity, with no significant differences in pA2 values (8.9 versus 8.2, respectively). Moxisylyte and NMI-221 showed moderate potency in antagonizing phenylephrine contraction, with comparable pA2 values for both molecules (6.5 versus 6.6, respectively). alpha-Adrenergic receptor-binding studies showed similar binding affinities for the alpha-ARA and their corresponding nitrosylated compounds. In vivo, intracavernosal injection of nitrosylated molecules caused greater increases in intracavernosal pressure (NMI-221 versus moxisylyte) that were more long lasting than those of moxisylyte or yohimbine. There were no significant differences between nitrosylated and non-nitrosylated compounds in the magnitude of systemic mean arterial pressure decrease after intracavernosal injection. alpha-ARA and the nitrosylated compounds showed no pain-inducing activity as evaluated with the paw-lick model in mice. In summary, nitrosylated alpha-ARA have the dual functionalities of nitric oxide donors and alpha-ARA. These drugs induced penile erection in animals, suggesting their possible therapeutic value as agents for the local pharmacological treatment of impotence. (+info)

Viagra for temporary erectile dysfunction during treatments with assisted reproductive technologies. (8/997)

During treatments with assisted reproductive technologies (ART), some men may have difficulties in producing spermatozoa on demand at the time of insemination, either for intrauterine insemination (IUI) or for in-vitro fertilization (IVF). This situation imposes tremendous stress on the couple and may cause cancellation of the treatment. Here we describe, for the first time, the use of sildenafil citrate (ViagraTM) for temporary erectile dysfunction in couples undergoing ART. The first case was a man who could not produce spermatozoa for the first IVF treatment after an exhausting trial for 12 h, despite the fact that he never had problems in providing sperm samples during previous IUI cycles. Using Viagra enabled him to provide spermatozoa, but the delay in oocyte insemination resulted in no embryonic development. This prompted us to be more alert to this option and to suggest the use of Viagra to men who had a history of erectile dysfunction during previous ART cycles. In these cases, the use of Viagra was planned in advance and it successfully solved any unpredictable erectile dysfunction on the day of insemination. Such cases emphasize the need to think in advance of this potential use of Viagra during ART. (+info)

Vardenafil (marketed as Levitra, Staxyn and Vivanza) was the second oral PDE-5 inhibitor for erectile dysfunction to be FDA ... There are now four oral erectile dysfunction (ED) drugs: Viagra (sildenafil) by Pfizer, Levitra (vardenafil) by Bayer ... Particular caution should be used when prescribing PDE5 inhibitors for erectile dysfunction for patients receiving protease ... Khera M, Goldstein I (June 2011). "Erectile dysfunction". BMJ Clinical Evidence. 2011. PMC 3217797. PMID 21711956. Henrie AM, ...

https://en.wikipedia.org/wiki/CGMP-specific_phosphodiesterase_type_5

"Erectile Dysfunction". The Lecturio Medical Concept Library. Retrieved 21 July 2021. Trost L, Elliott DS (2012). "Male stress ... Because all treatments can have significant side-effects, such as erectile dysfunction and urinary incontinence, treatment ... Cochrane Urology Group) (October 2018). "Penile rehabilitation for postprostatectomy erectile dysfunction". The Cochrane ...

https://en.wikipedia.org/wiki/Management_of_prostate_cancer

Ernst, E.; Pittler, M.H. (1998). "Yohimbe for Erectile Dysfunction: A Systematic Review and Meta-Analysis of Randomized ... Phentolamine, a non-selective alpha blocker, has also been tested to treat erectile dysfunction. By reducing vasoconstriction ... Lue, Tom F. (2009-08-20). "Erectile Dysfunction". New England Journal of Medicine. 342 (24): 1802-1813. doi:10.1056/ ... Giles Brindley in the first intracavernosal pharmacotherapy for erectile dysfunction. In benign prostatic hyperplasia (BPH), ...

https://en.wikipedia.org/wiki/Alpha_blocker

Erectile dysfunction Sildenafil PDE5 PDE5 inhibitor Molecular modelling Fiorito, J.; Zhang, H.; Staniszewski, A.; Feng, Y.; ... It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, ... Kedia, G.T.; Uckert, S.; Assadi-Pour, F.; Kuczyk, M. A. (2013). "Avanafil for the treatment of erectile dysfunction: initial ... Corbin, J. D. (2004). "Mechanisms of action of PDE5 inhibition in erectile dysfunction". Int J Impot Res. 16 (1): 4-7. doi: ...

https://en.wikipedia.org/wiki/Discovery_and_development_of_phosphodiesterase_5_inhibitors

It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand ... Sperling H, Lümmen G, Luboldt HJ, Rübben H (January 1999). "[Secondary erectile dysfunction. Is oral medication in the ... Erectile dysfunction drugs, GABAA receptor positive allosteric modulators, Hypnotics, Organobromides, Sedatives, Ureas, All ...

https://en.wikipedia.org/wiki/Acecarbromal

"Erectile dysfunction (impotence)". Evidence-Based Medicine Guidelines. Nov 30, 2018. Rove, Kyle. "Infertility in Men". DynaMed ... erectile dysfunction (impotence) and possibly reduced fertility (due to reduced libido and frequency of intercourse). Fathers ... HIV/AIDS Erectile dysfunction Ejaculation Disorders Hypoactive sexual desire disorder Other: Unintentional injuries Diabetes ...

https://en.wikipedia.org/wiki/Men's_health

Erectile Dysfunction: Estimates of the prevalence of erectile dysfunction in men with diabetes range from 20 to 85 percent when ... Dysfunction, Erectyle. "Erectile Dysfunction by Diabetes". doctor.ac. doctor.ac. Archived from the original on 2021-08-18. ... Among men with erectile dysfunction, those with diabetes are likely to have experienced the problem as much as 10 to 15 years ... Title LM, Ur E, Giddens K, McQueen MJ, Nassar BA (2006). "Folic acid improves endothelial dysfunction in type 2 diabetes - an ...

https://en.wikipedia.org/wiki/Complications_of_diabetes

... is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. ... Burke RM, Evans JD (2012). "Avanafil for treatment of erectile dysfunction: review of its potential". Vascular Health and Risk ... Sanford M (October 2013). "Avanafil: A Review of Its Use in Patients with Erectile Dysfunction". Drugs & Aging. 30 (10): 853-62 ... Avanafil is used to treat erectile dysfunction (ED). Although avanafil is generally well tolerated, dose dependent adverse ...

https://en.wikipedia.org/wiki/Avanafil

"Ginseng for erectile dysfunction". The Cochrane Database of Systematic Reviews. 2021 (4): CD012654. doi:10.1002/14651858. ... A 2021 review indicated that ginseng had "only trivial effects on erectile function or satisfaction with intercourse compared ...

https://en.wikipedia.org/wiki/Ginseng

Smoking is a key cause of erectile dysfunction (ED). It causes impotence because it promotes arterial narrowing and damages ... Korenman SG (2004). "Epidemiology of erectile dysfunction". Endocrine. 23 (2-3): 87-91. doi:10.1385/ENDO:23:2-3:087. PMID ... Incidence of erectile dysfunction is approximately 85 percent higher in male smokers compared to non-smokers. Several countries ... The usage of tobacco can also create cognitive dysfunction. There seems to be an increased risk of Alzheimer's disease (AD), ...

https://en.wikipedia.org/wiki/Health_effects_of_tobacco

Rhodes, Monica (2006). "Erection Problems (Erectile Dysfunction)". NYU Langone Medical Center. Archived from the original on ... Altovis Erectile dysfunction ExtenZe Penis enlargement Patent medicine "Why is this man smiling". USAToday. 2002-04-18. ... The manufacturer has claimed that Enzyte promotes "natural male enhancement," which is a euphemism for enhancing erectile ...

https://en.wikipedia.org/wiki/Enzyte

erectile dysfunction and incontinence). Added to this are characteristics such as immersive three-dimensional vision able to ...

https://en.wikipedia.org/wiki/Italian_robotics

If a male has erectile dysfunction (ED) while awake, but has NPT episodes during REM, it would suggest that the ED is from a ... Carson III, Culley C., Kirby, Roger S., Goldstein, Irwin, editors, "Textbook of Erectile Dysfunction" Oxford, U.K.; Isis ... Pathosphysiology of erectile dysfunction; a molecular basis, role of NPT in maintaining potency: pp. 105-15. Look up rapid eye ...

https://en.wikipedia.org/wiki/Rapid_eye_movement_sleep

Additionally, penile implants can be a relevant option for those with erectile dysfunction who wants to proceed with a ... In Peyronie's disease, the change in penile curvature affects normal sexual intercourse as well as causing erectile dysfunction ... A penile implant is an implanted device intended for the treatment of erectile dysfunction, Peyronie's disease, ischemic ... In spite of recent rapid and extensive development of non-surgical management options for erectile dysfunction, especially ...

https://en.wikipedia.org/wiki/Penile_implant

Dyspepsia (indigestion) Erectile dysfunction. This is most likely the result of hyperprolactinaemia. Decreased libido. This is ...

https://en.wikipedia.org/wiki/List_of_adverse_effects_of_olanzapine

Erectile dysfunction happens in different degrees in nearly all men who undergo prostate cancer treatment, including ... "Erectile Dysfunction After Prostate Cancer". www.hopkinsmedicine.org. 19 November 2019. Retrieved 2020-04-01. Parahoo K, ... Prostatectomy is associated with increased rates of urinary incontinence and erectile dysfunction, but these findings are based ... Because most treatments can have significant side effects, such as erectile dysfunction and urinary incontinence, treatment ...

https://en.wikipedia.org/wiki/Prostate_cancer

"Erectile Dysfunction After Prostate Cancer". www.hopkinsmedicine.org. 19 November 2019. Retrieved 2020-04-01. Prostate UK (UK ... Erectile dysfunction (difficulty getting and/or keeping an erection; impotence) is another side-effect associated with some ...

https://en.wikipedia.org/wiki/Prostate_brachytherapy

An Atlas of Erectile Dysfunction. Taylor & Francis (2003), ISBN 9781842142417 Your Guide to Prostate Cancer. Hodder Arnold ( ... 285-288 "Urethro-vesical dysfunction in progressive autonomic failure with multiple system atrophy", co-authored with Clare ...

https://en.wikipedia.org/wiki/Roger_Kirby

"Spider Venom for Erectile Dysfunction?". webmd.com. Archived from the original on 11 February 2015. Retrieved 11 February 2015 ... Such damage can result in erectile dysfunction or disfigurement of the penis. In extreme cases, if the penis develops severe ... The most common medications that cause priapism are intra-cavernous injections for the treatment of erectile dysfunction ( ...

https://en.wikipedia.org/wiki/Priapism

Bella AJ, Brock GB (2004). "Intracavernous pharmacotherapy for erectile dysfunction". Endocrine. 23 (2-3): 149-55. doi:10.1385/ ...

https://en.wikipedia.org/wiki/Phentolamine

Gynecomastia, testicular atrophy, erectile dysfunction. Increased transaminases. Musculoskeletal pain and discomfort. Dizziness ...

https://en.wikipedia.org/wiki/Degarelix

... is used as an erectile dysfunction drug, alone or sometimes in combination. Papaverine, when injected in penile ... Kim, E.; Elrashidy, R.; McVary, K. (1995). "Papaverine Topical Gel for Treatment of Erectile Dysfunction". The Journal of ... Bella, A. J.; Brock, G. B. (2004). "Intracavernous Pharmacotherapy for Erectile Dysfunction". Endocrine. 23 (2-3): 149-155. doi ... occasionally in the treatment of erectile dysfunction and acute mesenteric ischemia. While it is found in the opium poppy, ...

https://en.wikipedia.org/wiki/Papaverine

Tirado Sánchez A, León Dorantes G (Nov-Dec 2005). "Erectile dysfunction during isotretinoin therapy". Actas Urologicas ... There has been no link to birth defects from Accutane associated with males using the drug, though male sexual dysfunction has ...

https://en.wikipedia.org/wiki/IPLEDGE_program

In the US, it is prescribed, but now rarely, for erectile dysfunction in men. Yohimbine should not be confused with yohimbe but ... It has been prescribed as a treatment for erectile dysfunction, although its reported clinical benefits were modest and it has ... On treatment for male erectile dysfunction (ED), a review article by Tam et al. (2001) concluded: Although well-tolerated and ... Andersson KE (December 2011). "Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction". ...

https://en.wikipedia.org/wiki/Yohimbine

The drug was patented in 1996, approved for use in erectile dysfunction by the FDA on 27 March 1998, becoming the first oral ... "Hidden Risks of Erectile Dysfunction 'Treatments' Sold Online". US FDA. 21 February 2009. Retrieved 8 December 2020. R. Baselt ... In 1994, Pfizer filed a patent covering the use of sildenafil to treat erectile dysfunction. This would be marketed as Viagra. ... When taken by mouth sildenafil for erectile dysfunction results in an average time to onset of erections of 27 minutes (ranging ...

https://en.wikipedia.org/wiki/Sildenafil

"Obese men prone to erectile dysfunction". The Times of India. August 25, 2009. Archived from the original on March 23, 2012. " ...

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... and treatment of erectile dysfunction. Brindley is perhaps best known for an unusual scientific presentation at the 1983 Las ... Key Clinical Trials in Erectile Dysfunction. Springer. 2007. pp. 4-7. doi:10.1007/978-1-84628-428-1_2. ISBN 978-1-84628-427-4 ...

https://en.wikipedia.org/wiki/Giles_Brindley

Nagle M (10 September 2007). "Erectile dysfunction drug deemed a flop". Outsourcing Pharma. "Palatin 10K for the fiscal year ... Palatin conducted Phase II trials of intranasal bremelanotide in both female sexual dysfunction (FSD) and male erectile ... A New Drug Application of bremelanotide for female sexual dysfunction was accepted by the U.S. Food and Drug Administration ( ... To pursue the sexual dysfunction agent, melanotan II was licensed by Competitive Technologies to Palatin Technologies. Palatin ...

https://en.wikipedia.org/wiki/Bremelanotide

The FDA has also approved tadalafil for treatment of both BPH and erectile dysfunction (ED) where the two conditions co-exist. ... Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction (ED), benign ... McCarthy, Shawn (5 March 2005). "First they tried to play it safe; Ads for erectile dysfunction drug Cialis bared all - ... Parker-Pope, Tara (28 August 2009). "The Cost of Treating Erectile Dysfunction". The New York Times. Retrieved 20 December 2016 ...

https://en.wikipedia.org/wiki/Tadalafil

Erectile dysfunction occurred in "essentially all" patients in both groups. Leg edema occurred in 18% (17/95) of the estradiol ... and erectile dysfunction (90%; 19/21). The cardiovascular complications with estradiol undecylate in this relatively small ... sexual dysfunction, infertility, fluid retention, and cardiovascular issues. Estradiol undecylate is an estrogen and hence is ...

https://en.wikipedia.org/wiki/Estradiol_undecylate

Paul explains he has been suffering from erectile dysfunction and Ben suggests the source of the problem might be stress. The ...

https://en.wikipedia.org/wiki/Analyze_This

For men, the first sign can be erectile dysfunction. Women have also reported reduced genital sensitivity. As the disease ... Those who present at an older age, those with parkinsonian features, and those with severe autonomic dysfunction have a poorer ... MSA is also different from multiple organ dysfunction syndrome, sometimes referred to as multiple organ failure, and from ... Cunningham GR, Rosen RC (2018). "Overview of male sexual dysfunction.". In Martin KA (ed.). UpToDate. Waltham, MA: UpToDate. " ...

https://en.wikipedia.org/wiki/Multiple_system_atrophy

... by inverting the machismo of much rap music by rapping with enthusiasm about their erectile dysfunction problems ("We're Back ...

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This had the opposite effect, causing erectile dysfunction and genital pains. Alexander and then Lyudmila began to lure victims ...

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Ejaculation disorder Erectile dysfunction Orthostatic hypotension Weight gain (which it seems to possess a similar propensity ...

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... internationally renowned physician who was the lead author of the first paper on Viagra as it applied to erectile dysfunction. ...

https://en.wikipedia.org/wiki/Andrew_Goldstein

Sexual dysfunction usually appears early in synucleinopathies, and may include erectile dysfunction and difficulty achieving ... Autonomic dysfunction resulting from damage to nerves in the heart in patients with DLB is associated with lower cardiac uptake ... For autonomic dysfunction, several non-medication strategies may be helpful. Dietary changes include avoiding meals high in fat ... Dysautonomia (autonomic dysfunction) occurs when Lewy pathology affects the peripheral autonomic nervous system (the nerves ...

https://en.wikipedia.org/wiki/Dementia_with_Lewy_bodies

Oral sildenafil in the treatment of erectile dysfunction. 1998. Authors Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers, ... Author Steers, William D. Viability and safety of combination drug therapies for erectile dysfunction. Author Steers, William D ... Gineste Award for research in erectile dysfunction, the Zimskind Award in Neurourology, the annual Castle Connelly. Clinical ...

https://en.wikipedia.org/wiki/William_D._Steers

GlaxoSmithKline/Bayer's Levitra erectile dysfunction medicine, and The Hershey Company. Licensees include Glu Mobile, ...

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Mild cognitive impairment Erectile dysfunction HTLV-1 is associated with a rheumatoid-like arthropathy, although the evidence ... and sensory changes in the extremities Spastic gait in combination with weakness of the lower limbs Clonus Bladder dysfunction( ...

https://en.wikipedia.org/wiki/Human_T-lymphotropic_virus_1

Maggi M, Filippi S, Ledda F, Magini A, Forti G (August 2000). "Erectile dysfunction: from biochemical pharmacology to advances ... A common treatment for erectile dysfunction is sildenafil (Viagra). This compound is a potent inhibitor of cGMP specific ... An Unexpected Oral Therapy for Erectile Dysfunction". Sexual Medicine Reviews. 7 (1): 115-128. doi:10.1016/j.sxmr.2018.06.005. ...

https://en.wikipedia.org/wiki/Enzyme_inhibitor

This can lead to esophageal spasm and dysphagia, abdominal pain, erectile dysfunction, systemic hypertension, decreased organ ... erectile dysfunction, and thrombosis.16,17,23-26 In addition, systemic release of hemoglobin is associated with pulmonary and ... Chronic hemolysis may also lead to endothelial dysfunction, heightened endothelin-1-mediated responses and vasculopathy. The ...

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These include tadalafil (a PDE5 inhibitor for erectile dysfunction), retosiban (an oxytocin antagonist for preterm labor), ...

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... like diabetic neuropathy and erectile dysfunction, where the vibration perception threshold (VPT) would be higher than average ...

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Autonomic symptoms also may occur, such as dizziness on standing up, erectile dysfunction, and difficulty controlling urination ... some conditions affecting the brain or spinal cord also may cause autonomic dysfunction, such as multiple system atrophy, and ... Hypothyroidism Porphyria Vitamin B12 deficiency Vitamin B6 excess Those with diseases or dysfunctions of their nerves may ...

https://en.wikipedia.org/wiki/Peripheral_neuropathy

It was developed as a possible drug for the treatment of erectile dysfunction, although poor oral bioavailability means ... a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction". Journal of Medicinal ... an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction". Journal of Medicinal Chemistry. 49 (25 ...

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Vacuum therapy for erectile dysfunction". In Köhler TS, McVary KT (eds.). Contemporary Treatment of Erectile Dysfunction: A ... Medically approved VEDs, which treat erectile dysfunction, limit maximum pressure, whereas the pumps commonly bought by ... Although vacuum therapy can treat erectile dysfunction sufficiently to prevent penis deterioration and shrinkage, clinical ... and erectile dysfunction'". Medical doctors do treat micropenis with surgical procedures. In such cases, surgery can improve ...

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... erectile dysfunction, depression, seizures and other conditions), nasal polyps, non-allergic rhinitis (chronic congestion or ...

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"Soluble guanylate cyclase beta1-subunit expression is increased in mononuclear cells from patients with erectile dysfunction". ...

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... and sexual dysfunction such as erectile dysfunction or anorgasmia Serotonin and norepinephrine reuptake inhibitors (duloxetine ...

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Altered male hormones can also lead to erectile dysfunction which is the major cause of infertility in obese men. Gonadal heat ... Reis LO, Favaro WJ, Barreiro GC, de Oliveira LC, Chaim EA, Fregonesi A, Ferreira U (October 2010). "Erectile dysfunction and ... Other studies report sleep apnea decreases the quality of sex and increases the likelihood of erectile dysfunction. The ... Seftel A (February 2005). "Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men. A Randomized Controlled Trial". ...

https://en.wikipedia.org/wiki/Obesity_and_fertility

Sildenafil (Viagra), a treatment for erectile dysfunction, is patented by Pfizer. January 7 - A large blizzard hits the Eastern ... an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction". ...

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... used to treat erectile dysfunction). The hallucinogenic effects of lysergic acid diethylamide (LSD) were discovered by Albert ...

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... result in a slightly increased risk of sexual dysfunction with an incidence of decreased libido and erectile dysfunction of ... Men experience sexual dysfunction at testosterone levels of below 300 ng/dL, with men that have levels of testosterone of ... Vasopressin levels have been shown to increase during erectile response in male sexual arousal, and decrease back to baseline ... Worsley R, Santoro N, Miller KK, Parish SJ, Davis SR (March 2016). "Hormones and Female Sexual Dysfunction: Beyond Estrogens ...

https://en.wikipedia.org/wiki/Effects_of_hormones_on_sexual_motivation

Erectile dysfunction is the inability to develop and maintain an erection sufficiently firm for satisfactory sexual performance ... Goldenberg MM (1998). "Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction". Clinical ... The now-engorged erectile tissue presses against and constricts the veins that carry blood away from the penis. More blood ... The corpus spongiosum is an erectile tissue surrounding the urethra. The proximal parts of the corpus spongiosum form the bulb ...

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... particularly for treating male erectile dysfunction. However, the research was discontinued and focused on targeting female ... Since HSDD in men is not acknowledged and was categorized to be a distinct sexual dysfunction, there are currently no drugs ... Jing, Elizabeth; Straw-Wilson, Kristyn (2016-07-01). "Sexual dysfunction in selective serotonin reuptake inhibitors (SSRIs) and ... There are already 26 drugs available for men's sexual dysfunction. ...

https://en.wikipedia.org/wiki/Drugs_and_sexual_desire

Dean, Robert C.; Lue, Tom F. (2005-2011). "Physiology of Penile Erection and Pathophysiology of Erectile Dysfunction". The ... The increase of arterial flow during erection fills the erectile tissue with blood causing the glans to grow in size and ... The glans penis is a body of spongy erectile tissue that is moulded on the rounded ends of the two corpora cavernosa penis, ...

https://en.wikipedia.org/wiki/Glans_penis

Reduced fertility or infertility Erectile dysfunction Menstrual cycle and ovulatory disorders Women's health problems linked to ...

https://en.wikipedia.org/wiki/Sexual_and_reproductive_health

Detumescence is the reversal of this process, by which blood leaves the erectile tissue, returning the erectile tissue to the ... Male Sexual Dysfunction". In Tanagho, EA; McAninch, JW (eds.). Smith's General Urology (17th ed.). as DOC file at zju.edu.cn. ... Tumescence usually refers to the normal engorgement with blood (vascular congestion) of the erectile tissues, marking sexual ...

https://en.wikipedia.org/wiki/Tumescence

A still experimental erectile dysfunction drug -- avanafil -- promises erections in just 30 minutes or less, according to a ... Two of the other studies will look at how well the drug helps erectile dysfunction in men with diabetes and in men who have had ... The phase 3 study, not yet published in a peer-reviewed scientific journal, included 646 men with erectile dysfunction (ED). At ... Study Shows Erectile Dysfunction Drug Avanafil Works in 30 Minutes or Less ...

https://www.webmd.com/erectile-dysfunction/news/20091123/new-erection-drug-faster-safer

Is there an association between hyperthyroidism and erectile dysfunction? ... erectile dysfunction, n (%). Controls, n (%). Patients erectile dysfunction, n (%). Controls, n (%). Patients erectile ... erectile dysfunction, n (%). Controls, n (%). Patients erectile dysfunction, n (%). Controls, n (%). Patients erectile ... Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual ...

https://www.medscape.com/viewarticle/774869

In men with erectile dysfunction a blood flow to the penis is not enough to produce erection. The main component of Tadacip is ... There is no information about priapism when erectile dysfunction is treated by Tadacip, but in patients treated with with ...

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Men with erectile dysfunction (ED), or impotence, have trouble getting or keeping an erection. It is more common in older men. ... Erectile Dysfunction (ED) (American Academy of Family Physicians) Also in Spanish * Erectile Dysfunction (ED) (National ... Erectile Dysfunction and Diabetes (American Diabetes Association) * Erectile Dysfunction and Diabetes (Mayo Foundation for ... Erectile dysfunction (ED) is a common type of male sexual dysfunction. It is when a man has trouble getting or keeping an ...

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Erectile dysfunction (ED) affects 50% of men older than 40 years, exerting substantial effects on quality of life. This common ... encoded search term (Erectile Dysfunction) and Erectile Dysfunction What to Read Next on Medscape ... Erectile physiological and pathophysiological pathways involved in erectile dysfunction. J Urol. 2003 Aug. 170(2 Pt 2):S6-13; ... Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur Urol. 2010 May. 57 (5):804-14. [QxMD ...

https://emedicine.medscape.com/article/444220-medication

The drugs that treat erectile dysfunction are far from benign. Heres what your doctor would tell you about them-and why you ... Why erectile dysfunction meds can have serious side effects. The medical condition-and the drugs used to treat it-should be ... Psychological erectile dysfunction, for example, should be treated through therapy. "If you are getting up in the morning with ... When combined with erectile dysfunction medications, these drugs can cause blood pressure to plummet to dangerously low levels ...

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Erectile Dysfunction: Myths vs. Facts Understanding erectile dysfunction is the first step in treating it. Get the facts about ... Erectile Dysfunction 101 Erectile dysfunction (ED) affects up to 30 million American men. From causes and diagnosis to ... 8 Factors That Contribute to Erectile Dysfunction If you have Erectile Dysfunction (ED), getting your sex life back on track is ... Erectile Dysfunction - Prevention Kegels Are Not Just for Women When done properly and practiced regularly, Kegels can help men ...

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Nearly all men will experience some erectile dysfunction for the first few months after prostate cancer treatment. ... Erectile Dysfunction and Your Health: 5 Things You Need to Know Special Heart Risks for Men Erectile Dysfunction ... Erectile Dysfunction Following Radical Prostatectomy. Assuming the management of erectile dysfunction requires expert diagnosis ... Management of Erectile Dysfunction. Oral medications relax the muscles in the penis, allowing blood to rapidly flow in. On ...

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... erectile dysfunction - Answer: 100mg is the Maximum recommended daily dose. If thats still not working... ... erectile dysfunction. Similar questions. How much time does it take for a 100mg viagra dose to take effect? Iam a 66 year old ... Erectile Dysfunction - I can only get it up with Viagra, and the broad has to be on top and work?. Updated 18 July 2020 1 ... Erectile Dysfunction - What if 100mg of viagra doesnt work?. Question posted by 1969nr on 18 Feb 2017 ...

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Erectile dysfunction [‎ED]‎ is one of the most common diseases of male sexual dysfunction. A cross-sectional study of 388 ED ... Erectile dysfunction is a common health problem affecting the quality of life of men of all ages. The aim of this study was to ... Erectile dysfunction impairs the quality of life of millions of men worldwide. This study aimed to determine the relationship ... Prevalence and risk factors of erectile dysfunction among patients attending primary health care centres in Qatar ...

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Drawing of an inflatable implant to treat erectile dysfunction. An erection is produced by squeezing a small pump (a) implanted ... An inflatable implant to treat erectile dysfunction. View full-sized image Download Media Please credit each image as: National ... With an inflatable implant to treat erectile dysfunction. An erection is produced by squeezing a small pump (a) implanted in a ... Drawing of an inflatable implant to treat erectile dysfunction. An erection is produced by squeezing a small pump (a) implanted ...

https://www.niddk.nih.gov/news/media-library/17669

OverviewErectile dysfunction (impotence) is the inability to get and keep an erection firm enough for sex. ... Physical causes of erectile dysfunction. In many cases, erectile dysfunction is caused by something physical. Common causes ... For many people, erectile dysfunction is caused or worsened by lifestyle choices. Here are some steps that might help:. *If you ... Other medications for erectile dysfunction include:. * Alprostadil self-injection. With this method, you use a fine needle to ...

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These findings support the long-term use of tadalafil in the clinical management of erectile dysfunction. ... Long-term safety and tolerability of tadalafil in the treatment of erectile dysfunction Eur Urol. 2004 Mar;45(3):339-44; ... Objective: To assess the long-term safety and tolerability of tadalafil for patients with erectile dysfunction (ED). ... These findings support the long-term use of tadalafil in the clinical management of erectile dysfunction. ...

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Watermelon for Erectile Dysfunction. Escrito por Dr. Michael Greger • 31 may 12 Última actualización: 8 febrero 22 4:25 pm • ... video Watermelon as Treatment for Erectile Dysfunction, one plant in particular may be able to play an interim role. ... For more on diet and sexual dysfunction, please also check out Cholesterol and Female Sexual Dysfunction, Atkins Diet: Trouble ... narrowed coronary arteries have some degree of erectile dysfunction. There are drugs like Viagra, but theyre considered ...

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It can also result in erectile dysfunction (ED), or impotence. (qualityhealth.com)
Erectile dysfunction (impotence) is the inability to get and keep an erection firm enough for sex. (sparrow.org)
Erectile dysfunction, or impotence, is a type of sexual dysfunction that's generally defined as the inability to achieve an erection sufficient for sexual activity. (nm.org)
This is an extremely rare side effect, but if it goes untreated, can result in permanent erectile dysfunction (impotence). (meltingpointathens.com)
Erectile dysfunction, formerly called impotence, is a term that refers to the continued inability to obtain an acceptable erection for satisfactory sexual activity. (mayoclinichealthsystem.org)
Cenforce is one of the most well-known drugs in the world, used to treat erectile dysfunction, or ED, and impotence. (eumedz.com)
This is an overall oral medication for erectile dysfunction, premature ejaculation and impotence in men of any age group. (onlinegenericpillrx.com)
Sildenafil is applied for the treatment of erectile dysfunction (impotence) in men and pulmonary arterial hypertension. (rxreal.com)
Anecdotal reports from bicyclists had indicated that genital numbness, erectile dysfunction, and impotence are a concern. (cdc.gov)
However, one study reported that 21% of sport cyclists reported genital numbness after a bicycle race and 13% reported impotence 5 while other research reported a 61% incidence of genital numbness among cyclists and a 19% incidence in erectile dysfunction among cyclists riding more than 400 km (249 miles) per week. (cdc.gov)

Rapid Review Quiz: Erectile Dysfunction - Medscape - Aug 17, 2022. (medscape.com)

In men with erectile dysfunction a blood flow to the penis is not enough to produce erection. (viagracom24h.com)
Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse and is the most common sexual problem among aging male subjects. (medscape.com)
Men who do not recovery erectile function after treatment can try injectable medication that pharmacologically induced an erection. (hopkinsmedicine.org)
Erectile dysfunction, commonly referred to as ED, is the inability to achieve and sustain an erection suitable for sexual intercourse. (clevelandclinic.org)
Oral Citrulline Supplementation Improves Erection Hardness in Men With Mild Erectile Dysfunction. (nutritionfacts.org)
But if the inability to get and maintain an erection persists long enough to disrupt sex and intimacy, it may mean erectile dysfunction. (checkbiotech.org)
Erectile dysfunction (ED) is the inability to develop or maintain an erection of the penis during sexual performance. (medindia.net)
Erectile dysfunction is the "persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance. (bcmj.org)
Since erection, ejaculation, and orgasm are all neurologically separate, many men have discovered that orgasm is still possible despite significant erectile problems (e.g., those caused by diabetes) or ejaculatory alterations (e.g., no ejaculation after radical prostatectomy). (bcmj.org)
Several months ago, a group of Italian researchers hypothesized that there could be a connection between COVID-19 and erectile dysfunction-trouble getting and maintaining an erection. (verywellhealth.com)
Erectile dysfunction is a condition where a man is unable to achieve or maintain an erection suitable for sexual intercourse. (hivehealthmedia.com)
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To assess the long-term safety and tolerability of tadalafil for patients with erectile dysfunction (ED). (nih.gov)
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Tadalafil is one of the phosphodiesterase-5 inhibitors available that can help men in the general population who suffer from erectile dysfunction. (cancernetwork.com)
This trial was conducted to assess whether tadalafil would facilitate spontaneous erectile function in men treated with radiotherapy for prostate cancer. (cancernetwork.com)
The trial randomized 242 patients with full erectile function 1:1 to either placebo or 5 mg of tadalafil daily for 24 weeks starting at the time of their radiation therapy. (cancernetwork.com)
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Patients were surveyed with the 5-item International Index of Erectile Function (IIEF-5) and assessed for the presence of hypertension, diabetes and smoking. (who.int)
Multivariate analysis showed that hypertension (OR = 5.4), diabetes mellitus (OR = 5.4) and smoking (OR = 3.1) were significant risk factors for erectile dysfunction. (who.int)
Medications for erectile dysfunction do not work in all men and might be less effective in certain conditions, such as after prostate surgery or if you have diabetes. (wixsite.com)
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Roman is a men's health service that specializes in treatments for erectile dysfunction (ED) , premature ejaculation (PE) , and other men's health conditions. (healthline.com)

Nov. 23, 2009 - A still experimental erectile dysfunction drug -- avanafil -- promises erections in just 30 minutes or less, according to study results announced by the drug's manufacturer. (webmd.com)
The phase 3 study, not yet published in a peer-reviewed scientific journal, included 646 men with erectile dysfunction (ED). At the highest dose tested (200 milligrams), nearly 80% of sexual attempts resulted in erections good enough for intercourse. (webmd.com)
Men with erectile dysfunction, poor morning erections and low libido had a higher mortality risk compared to men with no sexual symptoms. (medicalxpress.com)
Oral erectile dysfunction medications are not aphrodisiacs, will not cause excitement and are not needed in men who get normal erections. (wixsite.com)
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A growing array of medications is available to assist in the management of erectile dysfunction (ED). An ideal agent would be rapidly effective, easy to administer, affordable, applicable to a wide range of patients, and minimally toxic. (medscape.com)
What medications could cause erectile dysfunction (ED)? (clevelandclinic.org)
If you enjoy your partner's company, it's likely that stress, anxiety, fatigue, specific medications or other health conditions are causing your erectile dysfunction. (mayoclinichealthsystem.org)
This study is meant to describe the mechanism of search redirection attacks in Google search results in relation to erectile dysfunction medications in European countries and also to determine the local and global scales of this problem. (jmir.org)
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On the basis of these study results, the physician should be able to determine the medical status of the patient, to identify and characterize the type of dysfunction, and to determine the need for additional testing (eg, penile or pelvic blood flow studies, nocturnal penile tumescence testing, or other blood tests). (medscape.com)
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For young men with ED and focal pelvic/penile arterial occlusion and without documented generalized vascular disease or veno-occlusive dysfunction, penile arterial reconstruction may be considered. (medscape.com)

Dietary Supplements for Erectile Dysfunction: A Natural Treatment for ED? (medlineplus.gov)
Nearly all men will experience some erectile dysfunction for the first few months after prostate cancer treatment. (hopkinsmedicine.org)
Assuming the management of erectile dysfunction requires expert diagnosis and treatment. (hopkinsmedicine.org)
We are particularly expert in the surgical treatment of patients with erectile dysfunction. (hopkinsmedicine.org)
Psychological treatment is an important adjunct to managing erectile dysfunction. (hopkinsmedicine.org)
Dr. Drogo Montague discusses treatment options for erectile dysfunction. (clevelandclinic.org)
video Watermelon as Treatment for Erectile Dysfunction , one plant in particular may be able to play an interim role. (nutritionfacts.org)
Missed dose is not supposed if Cialis is taken for treatment of erectile dysfunction as it's used when needed. (canadianpharm.org)
Among the 221 evaluable patients in the trial, 79% (80 patients) retained erectile function between weeks 28 and 30 after treatment compared with 74% (61 patients) who received placebo ( P = .49). (cancernetwork.com)
A simplified assessment approach that relies on questions about sexual history and a phy-sical exam can help with diagnosis and treatment of erectile dysfunction. (bcmj.org)
Alfuzosin is an effective treatment option for the management of patients with BPH/LUTS and concomitant sexual dysfunction. (meltingpointathens.com)
He or she will be able to make the proper referral for an erectile dysfunction treatment. (recordrestorations.com)
Misconceptions or misunderstandings about erectile dysfunction may cause some men to forgo treatment. (mayoclinichealthsystem.org)
A complete physical examination and medical history with a health care professional can help determine the cause of your erectile dysfunction and appropriate treatment options. (mayoclinichealthsystem.org)
Depending on the cause and severity of your erectile dysfunction and any underlying health conditions, you might have various treatment choices. (windows.net)
While there are no guarantees that the treatment will work for you, the results for F-SW are extremely encouraging for Erectile Dysfunction (ED), Peyronie's Disease (PD), or Chronic Pelvic Pain Syndrome (CPPS). (focuswaveclinic.com)
References Sexual dysfunction in men - when Viagra doesn't work Goodfellow Unit, NZ, 2019 Erectile dysfunction BPAC, NZ, 2008 Erectile problems Best Health, UK, 2014 Dietary supplements for erectile dysfunction - a natural treatment for ED? (viagrafor.com)
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An October 2021 study in Andrologia found that losing weight improved erectile function in people with overweight or obese. (livestrong.com)

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This erectile dysfunction is often associated with decreased libido, orgasm or ejaculation disorder. (biosantepharma.com)

Erectile dysfunction can severely impact a man's wellbeing and quality of life beyond the inability to have intercourse. (nm.org)
Whereas erectile dysfunction can be caused by the inability of blood vessels to open up, too much constriction of the blood vessels is problematic, too. (verywellhealth.com)

Cycling may lead to erectile dysfunction as sitting on the saddle could be crushing your private parts, which means the pressure is falling on your nerves of your private parts. (blogarama.com)
This can cause tingling or numbness in the penis and may eventually lead to erectile dysfunction as well. (blogarama.com)
Apart from cycling, there can be several other risk factors which can lead to erectile dysfunction. (blogarama.com)
1. Lifestyle selections, such as smoking, alcohol abuse, and obesity may hamper blood circulation and lead to erectile dysfunction. (maxayurveda.in)

Before taking any medication for erectile dysfunction, including over-the-counter supplements and herbal remedies, get your doctor's OK. (wixsite.com)

Two of the most embarrassing conditions a man could encounter during sexual intercourse are erectile dysfunction and premature ejaculation. (penisenlargementmethods.net)
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The best way to prevent erectile dysfunction is to make healthy lifestyle choices and to manage any existing health conditions. (sparrow.org)
Research from Wroclaw Medical University in Poland suggests that male cyclists should regularly stand up when biking to prevent erectile dysfunction. (blogarama.com)
Alternative strategies to prevent erectile dysfunction in this context appear warranted, perhaps with attention toward alternative dosing, investigation of neuroprotective interventions, or further refinements of radiotherapy delivery methods," added the authors. (cancernetwork.com)

While most would rely on the ginseng alone to help with erectile dysfunction, the oil also uses other herbal ingredients that have been tried and tested to also be very effective aphrodisiacs. (penisenlargementmethods.net)

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If our diagnosis suggests a psychological association with your erectile dysfunction, we may recommend that you pursue counseling with a qualified psychologist available through the Clinic. (hopkinsmedicine.org)

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Erectile dysfunction could be due to a lack of blood flow or have a more psychological root cause. (livestrong.com)
Erectile dysfunction is often a psychological issue that can affect relationships and cause a man to feel insecure. (recordrestorations.com)
In the past, psychological factors alone were thought to cause erectile dysfunction. (mayoclinichealthsystem.org)
While this could be the result of psychological trauma, surgery, or a bad lifestyle, cases of erectile dysfunction are enough for companies all over the world to start creating their own solutions to the problem. (penisenlargementmethods.net)

A cross-sectional study of 3921 Canadian men, age 40 to 88, found the overall prevalence of erectile dysfunction (ED) was 49.4%,[ 1 ] and therefore ED affects an estimated 3 million Canadian men over the age of 40. (bcmj.org)
Vitamin D deficiency is associated with an increased prevalence of erectile dysfunction (ED) independent of risk factors for atherosclerotic cardiovascular disease (ASCVD), according to a new study. (renalandurologynews.com)
The investigators also noted that men with ED have an increased prevalence of endothelial dysfunction, and vitamin D may improve endothelial function. (renalandurologynews.com)
Researchers estimate the global prevalence of erectile dysfunction (ED) to range from 3% to 76.5% , depending greatly on increasing age. (medscape.com)

A study has found that more than 26 percent of Chinese men suffer from erectile dysfunction. (medindia.net)
Recent studies indicate that around 52% of men suffer from erectile dysfunction at some point during their lives. (arizona-urology.com)
Erectile dysfunction (ED) best Treat Like Cenforce 100 result of good It climbs by 5 percent to 15 percent from age 40 to 70, although young males may also suffer from the disease. (healthtips7.info)

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Despite all of these advantages, not all studies have indicated that frequent coffee use may alleviate the symptoms of erectile dysfunction. (healthtips7.info)

Although the etiology of ED is complex and understood to be the result of interplay between altered erectile nerve function, cognitive decline, illness-related stress and decreased interpersonal interaction, [ 10 , 11 ] both the pathology of ED and dysthyroidism have been highlighted as sharing common underlying endocrine dysfunction. (medscape.com)
No significant difference was observed in erectile function between the experimental group and the placebo group. (cancernetwork.com)
Prolonged-release alfuzosin effectively improved LUTS, quality of life, erectile function, and sexual satisfaction in men with BPH and mild to severe erectile dysfunction. (meltingpointathens.com)
Conclusion: Tamsulosin HCl capsules showed a significant statistical improvement in the erectile function, sexual desire, and intercourse satisfaction score with significant improvement in total IIEF in patients with lower urinary tract symptoms because of benign prostatic hyperplasia. (meltingpointathens.com)
They pointed out, however, that additional research, such as randomized controlled clinical trials, is needed to determine whether treating vitamin D deficiency can improve erectile function. (renalandurologynews.com)
Some erectile function changes with age. (mayoclinichealthsystem.org)
L'étude était basée sur l'Index International de la Fonction Érectile contenant 5 items (5-item International Index of Erectile Function ou IIEF-5) et les patients étaient contrôlés au niveau de l'hypertension, du diabète et du tabagisme. (who.int)
A study reported in the Journal of Sexual Medicine found that males with erectile dysfunction who took 1,5o0 milligrams of niacin for a 12-week period showed significant improvements in erectile function. (cialzi.com)
Hence, the parasympathetic system is the main neural component for erectile function. (cialzi.com)
Men with erectile dysfunction Dysfunctions have the ability to improve sexual function by making some changes. (maxayurveda.in)
The research also says that treating gum disease by reducing inflammation of the gums can result in improved erectile function. (hippocraticpost.com)
Men with sudden onset of erectile dysfunction without having a history of any sexual dysfunction could have psychogenic cause which could be due to previous genital trauma or previous surgeries pertaining to sexual function. (onlinegenericpillrx.com)
Is Caffeine's Effect on Erectile Function Still Up for Debate? (healthtips7.info)
Men with ED who have comorbidities known to negatively affect erectile function should be counseled that lifestyle modifications, including changes in diet and increased physical activity, improve overall health and may improve erectile function. (medscape.com)
Therefore, we aimed to investigate the erectile function at three months after COVID-19 recovery along with its predicting factors. (bvsalud.org)
Demographic data , mental health status, and erectile function were collected at baseline and prospectively recollected three months after hospital discharge. (bvsalud.org)
The study found a 66% reduction in saddle contact pressure in the perineal region, a significant improvement in penis tactile sensation, and a significant improvement in erectile function. (cdc.gov)
The objectives of this study were to investigate the association of genetic variants of DDAH1 (rs1554597 and rs18582) and DDAH2 (rs805304 and 805305) with vulnerability to develop ED, with altered scores of erectile function and with altered plasma concentrations of nitrite and ADMA. (bvsalud.org)
We also investigated whether these biochemical markers associated with erectile function scores and ED risk. (bvsalud.org)
We selected 130 patients with clinical ED and 98 healthy controls without ED. Erectile function was assessed through the International Index for Erectile Function (IIEF) questionnaire. (bvsalud.org)
The clinical responses to sildenafil were evaluated and the patients were classified as good responders (GR) or poor responders (PR) when their changes in five-item version of International Index for Erectile Function questionnaire were above or below the median value. (bvsalud.org)

Erectile dysfunction following radical prostatectomy for clinically localized prostate cancer is a known potential complication of the surgery. (hopkinsmedicine.org)

We now see erectile dysfunction as an indicator of vascular health and a sentinel marker for cardiovascular risk stratification. (bcmj.org)
Dr Michos and her colleagues discussed various mechanisms that could explain a biologic relationship between vitamin D deficiency and ED . For example, vascular ED results from endothelial dysfunction and/or atherosclerosis. (renalandurologynews.com)
Erectile dysfunction is doubtlessly connected to a vascular connection. (busineshope.com)

There is no information about priapism when erectile dysfunction is treated by Tadacip, but in patients treated with with another PDE5 inhibitor sildenafil it may occur. (viagracom24h.com)
This article investigates the erectile and ejaculatory status in patients with anal fissure. (nature.com)
Erectile dysfunction persisted in the four patients in whom the fissures did not heal. (nature.com)
To investigate clinical correlates further, researchers led by Elisa Bandini of the University of Florence studied approximately 2,000 male patients in a clinic for sexual dysfunction using a structured interview while also scoring for depressive symptoms. (medindia.net)
The issues involved in erectile dysfunction are very similar to what's seen in patients with heart disease. (nm.org)
We studied 71 post-prostatectomy erectile dysfunction (ED) patients (PED group) and 72 clinical ED patients (CED). (bvsalud.org)

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Much like the former one, Generic Levitra has potent effects in treating male erectile dysfunction problems, this is also known as Vardenafil as this the active drug content in the medication. (onlinegenericpillrx.com)
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If the primary cause of your erectile dysfunction is emotional rather than physical, your urologist may recommend therapy with a mental health professional. (arizona-urology.com)

Before going for pharmacological help doctors may suggest complete positive change in lifestyle habits because most of the cases of erectile dysfunction were a cause of unhealthy lifestyle habits like smoking, drinking and using drugs. (onlinegenericpillrx.com)

As noted in a recent article in the Harvard Health Letter, up to three- quarters of men with cholesterol--narrowed coronary arteries have some degree of erectile dysfunction. (nutritionfacts.org)
Over 50% of men experience some degree of erectile dysfunction in their lifetime. (hormonetherapyntx.com)

Study investigator LeRoy Jones, MD, associate professor of urology at the University of Texas Health Science Center, said the new drug will offer a new alternative to men seeking "an improved experience" with current erectile dysfunction drugs. (webmd.com)
While seeing permanent red is an extreme example, it serves as a good reminder that drugs to treat erectile dysfunction are just that-ones used to treat a true medical condition that carry real side effects. (popsci.com)
Erectile dysfunction (ED) is a common side effect of a number of prescription drugs. (clevelandclinic.org)
What prescription drugs may cause erectile dysfunction? (clevelandclinic.org)
Most narcotic drugs act as a depressant on the brain, central nervous system, hormones and other parts of the body, and thus result in erectile dysfunction.Â While alcohol leaves the system rather quickly, usually within 12 hours, narcotics can stay in the nervous system and blood stream for up to 48 hours, and their effects on the body, brain and central nervous system will last longer. (hivehealthmedia.com)
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Given the consumer interest in erectile dysfunction drugs, it should come as no surprise to learn that there are people out there willing to exploit said interest for their own malicious purposes. (securemedical.com)
Even worse, the cash that can be made selling counterfeit erectile dysfunction drugs means that the problem is becoming more and more common as more and more criminals take up the practice. (securemedical.com)
what's the best erectile dysfunction drugs for men who may have achieved in their sexual life, and it's not the same way to elongate. (gugel-kvg.de)

A study in The Journal of Urology found that if the handlebar height is parallel or higher than the saddle, then it can increase your risk of erectile dysfunction compared with handlebars at a height lower than the saddle's height. (blogarama.com)

The woman is confronted with disorders of desire, sexual arousal with vaginal dryness, or an orgasm disorder, an insufficiently erectile clitoris, pain during intercourse. (biosantepharma.com)
These medicines may cause erectile dysfunction, decreased arousal, and orgasm dysfunction. (cdc.gov)

It's not a quick fix, but for people with overweight or obesity, slimming down is the most effective way to improve your below-the-belt performance if you have erectile dysfunction (ED). (livestrong.com)
Exercise reduces the likelihood of obesity, a risk factor for erectile dysfunction. (netnewsledger.com)

Anatomy4

Organisms7

Diseases16

Chemicals and Drugs21

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Psychiatry and Psychology7

Phenomena and Processes5

Information Science2

Health Care10

Geographicals1

Comparison of the 5-year outcome and morbidity of three-dimensional conformal radiotherapy versus transperineal permanent iodine-125 implantation for early-stage prostatic cancer. (1/997)

Determination of intrapenial blood volume using 99mTc-labeled autologous red blood cells. (2/997)

Sexual functioning among stroke patients and their spouses. (3/997)

Health economics and sexual dysfunction. Based on a presentation by Cyril F. Chang, PhD. (4/997)

Managed care and sexual dysfunction. Based on a presentation by William Parham, MD. (5/997)

Secondary infertility as early symptom in a man with multiple endocrine neoplasia-type 1. (6/997)

Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence. (7/997)

Viagra for temporary erectile dysfunction during treatments with assisted reproductive technologies. (8/997)

Erectile Dysfunction

Penile Erection

Impotence, Vasculogenic

Penis

Sulfones

Phosphodiesterase 5 Inhibitors

Penile Prosthesis

Purines

Phosphodiesterase Inhibitors

Carbolines

Penile Implantation

Piperazines

Priapism

Alprostadil

Sexual Dysfunctions, Psychological

Sexual Dysfunction, Physiological

Penile Induration

Libido

Urological Agents

Cyclic Nucleotide Phosphodiesterases, Type 5

Triazines

Papaverine

Ergoloid Mesylates

Vasodilator Agents

Coitus

Sex Counseling

Urologic Diseases

3',5'-Cyclic-GMP Phosphodiesterases

Ejaculation

Butea

Testosterone

Ventricular Dysfunction, Left

Hypogonadism

Treatment Outcome

Vacuum

Injections

Urethra

Set (Psychology)

Prevalence

Premature Ejaculation

Tribulus

Risk Factors

Qatar

Epimedium

Prostatectomy

Penile Diseases

Orgasm

Patient Satisfaction

Apomorphine

Urination Disorders

Carthamus

Cynomorium

Questionnaires

Phentolamine

Double-Blind Method

Severity of Illness Index

Imidazoles

Endothelium, Vascular

Men's Health

Lepidium

Nitric Oxide Synthase Type I

Prostatism

Urinary Incontinence

Diabetes Complications

Nitric Oxide

Adrenergic alpha-Antagonists

Cardiovascular Diseases

Muscle, Smooth

Panax

Eunuchism

Comparison of the 5-year outcome and morbidity of three-dimensional conformal radiotherapy versus transperineal permanent iodine-125 implantation for early-stage prostatic cancer. (1/997)

Determination of intrapenial blood volume using 99mTc-labeled autologous red blood cells. (2/997)

Sexual functioning among stroke patients and their spouses. (3/997)

Health economics and sexual dysfunction. Based on a presentation by Cyril F. Chang, PhD. (4/997)

Managed care and sexual dysfunction. Based on a presentation by William Parham, MD. (5/997)

Secondary infertility as early symptom in a man with multiple endocrine neoplasia-type 1. (6/997)

Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence. (7/997)

Viagra for temporary erectile dysfunction during treatments with assisted reproductive technologies. (8/997)

2020-08-10 Erectile Dysfunction Medications Erectile Dysfunction Feature Stories - Application Technology Co. Ltd.

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