Epithelial Attachment
Regulated expression of nullo is required for the formation of distinct apical and basal adherens junctions in the Drosophila blastoderm. (1/40)
During cellularization, the Drosophila embryo undergoes a large-scale cytokinetic event that packages thousands of syncytial nuclei into individual cells, resulting in the de novo formation of an epithelial monolayer in the cortex of the embryo. The formation of adherens junctions is one of the many aspects of epithelial polarity that is established during cellularization: at the onset of cellularization, the Drosophila beta-catenin homologue Armadillo (Arm) accumulates at the leading edge of the cleavage furrow, and later to the apicolateral region where the zonula adherens precursors are formed. In this paper, we show that the basal accumulation of Arm colocalizes with DE-cadherin and Dalpha-catenin, and corresponds to a region of tight membrane association, which we refer to as the basal junction. Although the two junctions are similar in components and function, they differ in their response to the novel cellularization protein Nullo. Nullo is present in the basal junction and is required for its formation at the onset of cellularization. In contrast, Nullo is degraded before apical junction formation, and prolonged expression of Nullo blocks the apical clustering of junctional components, leading to morphological defects in the developing embryo. These observations reveal differences in the formation of the apical and basal junctions, and offer insight into the role of Nullo in basal junction formation. (+info)Human endometrial mucin MUC1 is up-regulated by progesterone and down-regulated in vitro by the human blastocyst. (2/40)
Expression of MUC1 in endometrial epithelium has been suggested to create a barrier to embryo attachment that must be lifted at the time of implantation. In this study, we investigated the hormonal regulation of human endometrial MUC1 in hormone replacement therapy cycles and in the human blastocyst. We also analyzed the embryonic regulation of MUC1 in human endometrial epithelial cells (EECs) during the apposition and adhesion phases of human implantation using two different in vitro models. Our results indicate that endometrial MUC1 mRNA and immunoreactive protein increase in receptive endometrium compared to nonreceptive endometrium. Human blastocysts express MUC1, as demonstrated by reverse transcription-polymerase chain reaction and immunocytochemistry, localized at the trophectoderm. In vitro, MUC1 was present at the surface of primary cultures of human EEC, and presence of a human blastocyst (i.e., apposition phase) increases EEC MUC1 protein and mRNA compared to control EEC lacking embryos. Interestingly, when human blastocysts were allowed to attach to the EEC monolayer (i.e., adhesion phase), MUC1 was locally removed in a paracrine fashion on EEC at the implantation site. These results demonstrate a coordinated hormonal and embryonic regulation of EEC MUC1. Progesterone combined with estradiol priming induces an up-regulation of MUC1 at the receptive endometrium. During the apposition phase, presence of a human embryo increases EEC MUC1. However, at the adhesion phase, the embryo induces a paracrine cleavage of EEC MUC1 at the implantation site. These findings strongly suggest that MUC1 may act as an endometrial antiadhesive molecule that must be locally removed by the human blastocyst during the adhesion phase. (+info)Proliferative response of cells of the dentogingival junction to mechanical stimulation. (3/40)
The aim of this research was to study the proliferative response of junctional epithelium (JE) and gingival connective tissue (GCT) to mechanical stimulation in vivo with regard to the potential occurrence of apical migration of JE and loss of GCT attachment during orthodontic tooth movement. Elastic bands were inserted between the maxillary first and second molars of male rats aged 8 weeks, which were pulse-labelled with 3H-thymidine and subsequently killed in groups, together with labelled control animals (a total of 98 rats) after periods of 1-168 hours. Autoradiographs were prepared from plastic mesiodistal sections, and parameters of cell proliferation for JE and GCT of the papilla between the second and third molars were determined. Although the distance between the apical limit of JE and the most coronal periodontal ligament (PDL) fibres decreased on the pressure and increased on the tension sides of mechanically stimulated animals, the total cross-sectional area of JE remained unchanged compared with controls. In the basal and suprabasal layers of JE, cell proliferation was reduced on the pressure side and showed no change on the tension side. In the apical JE compartments on both sides, mechanical stressing resulted in lower proliferative activity. Cell proliferation in GCT adjacent to JE in stimulated animals did not differ from the corresponding controls. JE rapidly adapted to mechanical stimulation by means of differential local adjustments of cell proliferation without an occurrence of apical migration or hyperplasia. GCT cells in the vicinity of JE maintained their steady-state proliferative activity. These results do not support the concept that orthodontic tooth movement might per se have detrimental effects on the stability of the dentogingival junction. (+info)Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells. (4/40)
Conjugated linoleic acid (CLA) is a collective term referring to the positional and geometric isomers of linoleic acid. This novel fatty acid has been shown to have a number of beneficial actions, including immunomodulatory, anticarcinogenic, and antiatherogenic effects. Tight junctions of epithelial cells determine epithelial membrane integrity and selective paracellular permeability to ions and macromolecules. Occludin and ZO-1 are integral structural components of the tight junction, which are involved in the biogenesis and functional integrity of the epithelial monolayer. This study investigated the effects of two isomers of CLA (cis-9 and trans-10 isomers) on Caco-2 cell transepithelial resistance (TER) development, paracellular epithelial permeability, and occludin and ZO-1 expression. Caco-2 cells were grown in media supplemented with 0.05 mM linoleic acid, cis-9 CLA, or trans-10 CLA for 21 days. The trans-10 CLA isomer delayed Caco-2 cell TER development, which is an in vitro measure of epithelial cell integrity, and increased paracellular epithelial permeability. Immunofluorescent staining of Caco-2 cell epithelial monolayers grown in media supplemented trans-10 CLA showed that the trans-10 CLA isomer altered distribution of occludin and ZO-1. The trans-10 CLA isomer delayed the acquisition of transepithelial resistance and altered the cellular distribution of occludin, which have important implications in relation to epithelial permeability. (+info)Blood-brain barrier function in cerebral malaria in Malawian children. (5/40)
Cerebral malaria (CM) is a serious complication of Plasmodium falciparum infection. Binding of parasitized erythrocytes to cerebral endothelium plays a key role in disease pathogenesis. Central nervous system signs and symptoms (coma, seizures, raised intracranial pressure) predominate in African children, whereas in adults, multiorgan system failure is more common. In this study we investigated whether changes in blood-brain barrier (BBB) structure and function are compatible with the signs and symptoms observed in Malawian children with CM. Immunohistochemistry on autopsy brain tissues from eight cases of CM showed activation of endothelial cells and macrophages, and disruption of endothelial intercellular junctions in vessels containing sequestered parasitized erythrocytes, but no gross leakage of plasma proteins. Examination of the partition of albumin between circulating plasma and the cerebrospinal fluid from 72 cases of CM showed subtle but measurable changes compatible with impaired BBB function in malaria. These findings suggest that BBB breakdown occurs in areas of parasite sequestration in CM in African children. (+info)Mesio-marginal findings at tilted molars. A histological-histomorphometric study. (6/40)
The aim of this study was to investigate the mesio-marginal findings at tilted molars (TM) by means of histological-histomorphometric evaluation. Eight lateral tooth bone segments with TM (six mandibular, two maxillary) from males aged 20-32 years were compared with those of eight samples with non-tilted molars (NTM) in males aged 18-35 years. In comparison with the NTM samples, the TM revealed a higher amount of supra- and subgingival plaque, a significantly higher total number of inflammatory cells (P < 0.05) and blood vessels (P < 0.05) in the connective tissue adjacent to the junctional epithelium, and a lower density and corono-apical width of gingival fibres. No significant differences (P > 0.05) were found between the mesio-marginal bone level of the TM (mean: 978 microns) and that of the NTM (mean: 1222 microns). In contrast, indications were found that TM may affect the disto-marginal bone level of the mesial tooth. (+info)Esthetic periodontal considerations in orthodontic treatment--the management of excessive gingival display. (7/40)
This paper examines various esthetic periodontal considerations during orthodontic treatment. The management of excessive gingival display caused by altered passive eruption is reviewed, with emphasis on causes, recognition, diagnosis and surgical management of this problem. A case of orthodontic treatment of excessive gingival display associated with altered passive eruption of the maxillary incisors is reviewed to demonstrate appropriate management. With proper diagnosis, soft-tissue periodontal procedures after completion of orthodontic treatment can enhance the patient's final appearance. (+info)Unique creeping attachment after autogenous gingival grafting: case report. (8/40)
This case report describes a unique creeping attachment that developed mesiobucally on a deep, wide recession (3 mm) and extended along the remaining buccal recession (2 mm) of a maxillary first molar with a full-crown gold restoration subsequent to autogenous gingival grafting. Complete coverage of the root by this degree of creeping attachment on a restored multirooted tooth has not previously been reported in the dental literature. (+info)'Epithelial attachment' refers to the point where the epithelial cells of the oral cavity, such as the gum tissue, physically adhere and structurally connect to the tooth surface via the junctional epithelium and hemidesmosomes.
Epithelial attachment is a general term that refers to the point where epithelial cells, which are the cells that line the outer surfaces of organs and blood vessels, adhere or attach to an underlying structure. In the context of the mouth and teeth, epithelial attachment is often used to describe the connection between the gum tissue (gingiva) and the tooth surface.
In a healthy mouth, the gingival tissue fits tightly around each tooth, forming a protective seal that helps prevent bacteria and other harmful substances from entering the spaces between the teeth and gums. This tight seal is maintained by specialized epithelial cells called junctional epithelial cells, which form a barrier between the oral environment and the underlying connective tissue.
When the gingival tissue becomes inflamed due to factors such as poor oral hygiene or certain medical conditions, the epithelial attachment can become compromised, leading to a condition known as gingivitis. If left untreated, gingivitis can progress to periodontal disease, which is characterized by the destruction of the tissues that support the teeth, including the bone and connective tissue.
In summary, epithelial attachment refers to the point where epithelial cells adhere to an underlying structure, and in the context of oral health, it describes the connection between the gum tissue and the tooth surface.
Object attachment in a medical context is not a widely recognized term, but in the field of psychology, it can refer to an unhealthy emotional dependence on a particular object or person, which may interfere with daily functioning and relationships.
I'm sorry for any confusion, but "object attachment" is not a term that has a specific medical definition in the way that a term like "myocardial infarction" (heart attack) or "major depressive disorder" does. It may be used in various ways in different contexts, such as in psychology or psychiatry to describe a phenomenon where an individual becomes excessively attached to an object or items, but it is not a widely recognized or standardized term in medical terminology. If you are referring to a specific concept or diagnosis and could provide more context, I would be happy to help further!
Membrane vesicle trafficking
"Characteristics of Helicobacter pylori attachment to human primary antral epithelial cells". Microbes and Infection. 2 (14): ... These vesicles were suspected to promote bacterial adhesion to the host epithelial cell surface. Their role in invasion of ... Role of OMVs in Helicobacter pylori infection of human primary antral epithelial cells, as model that closely resembles human ... Salmonella OMVs were also shown to have direct role in invasion of chicken ileal epithelial cells in vivo in the year, 1993 ( ...
Asthma-related microbes
It may cause injury to the respiratory epithelial cell after its attachment. The injury of host epithelial cells caused by M. ... and fatty acids obtained from the mucosal epithelial cells of the host. Its adhesion proteins attach to tracheal epithelial ... According to Hertzen (2002), a common characteristic of asthmatic patients is to have epithelial cells that respond to injury ... 1976) suggests that M. pneumoniae infection denude the epithelial surface and expose irritant receptors. On top of that, M. ...
Intestinal mucosal barrier
SIgA blocks epithelial-specific receptors on pathogens, thereby preventing their attachment to epithelial cells. A variety of ... Specialised secretory epithelial cells called Paneth cells secrete abundant quantities human α-defensins into the intestinal ... It consists of the layer of epithelial cells lining the intestine. Crucial for forming an effective barrier is the precise ... The secretion of various molecules into the lumen reinforces the barrier function on the extra-epithelial side, while a variety ...
Westralunio carteri
Following attachment to their host fish, the glochidia are encased by epithelial cells, which forms a cyst,. They remain in the ...
Lyme disease microbiology
OspA promotes the attachment of B. burgdorferi to the tick protein TROSPA, present on tick gut epithelial cells. OspB also has ... Upregulation of OspC begins during the first day of feeding and peaks 48 hours after attachment. The OspA and OspB genes encode ... it is not essential for the attachment and colonization of the tick gut, and it is not required for human infections. OspC is a ...
Signal transduction
... cell membrane integrins on circulating leukocytes are maintained in an inactive state to avoid epithelial cell attachment; they ... Integrins are produced by a wide variety of cells; they play a role in cell attachment to other cells and the extracellular ... Epithelial cells (which are non-circulating) normally have active integrins at their cell membrane, helping maintain their ... The prevalence of basement membranes in the tissues of Eumetazoans means that most cell types require attachment to survive. ...
Tooth resorption
... below the epithelial attachment. It is distinguished from external inflammatory root resorption in that it rarely involves the ...
Gingival and periodontal pocket
The epithelial attachment does not migrate, it simply remains at the same attachment level found in pre-pathological health. ... Located at the depth of the sulcus is the epithelial attachment, consisting of approximately 1 mm of junctional epithelium and ... Continuous destruction of surrounding tissues due to inflammation will lead to degradation of attachment and bone, eventually ... another 1 mm of gingival fiber attachment, comprising the 2 mm of biologic width naturally found in the oral cavity. The sulcus ...
Pinopode
With the development of pinipodes, there is a decrease in epithelial cell contact, which prompts blastocyst attachment and ... The implantation window is known as the period of time in which the endometrium is receptive to blastocyst attachment. Due to ... Pinopodes (also known as pinopods and uterodomes) are protrusions on the apical cellular membrane of uterine epithelial cells. ... pinopode development overlapping with the implantation window, blastocyst attachment takes place, which provides adhesion ...
Senior dog diet
MOS works in a different manner by effecting the attachment of bad bacteria in the gut of the dog. These bad bacteria attach to ... This process is important in maintaining a healthy coat in the aging dog and preventing the deterioration of epithelial tissues ... the epithelial lining of the gastrointestinal tract and can cause the beginnings of pathogenic diseases. MOS works to ...
Adherens junction
... s uniquely disassemble in uterine epithelial cells to allow the blastocyst to penetrate between epithelial ... They can appear as bands encircling the cell (zonula adherens) or as spots of attachment to the extracellular matrix (focal ... A similar cell junction in non-epithelial, non-endothelial cells is the fascia adherens. It is structurally the same, but ... are protein complexes that occur at cell-cell junctions and cell-matrix junctions in epithelial and endothelial tissues, ...
Reduced enamel epithelium
The degeneration of reduced enamel epithelium also mediates the initial epithelial attachment to the tooth, which is called the ...
Trophinin
... a complex mediating unique attachment between trophoblastic and endometrial epithelial cells at their respective apical cell ... between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during ... and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells". ...
Human tooth
These three types form from a mass of epithelial cells known as the epithelial cuff between the tooth and the mouth. The ... The functions of the periodontal ligaments include attachment of the tooth to the bone, support for the tooth, formation and ... The growth of cervical loop cells into the deeper tissues forms Hertwig's Epithelial Root Sheath, which determines a tooth's ... The junctional epithelium, composed of the basal lamina and hemidesmosomes, forms an attachment to the tooth. The sulcular ...
Bordetella
As well as assisting in adherence to epithelial cells, some of these are also involved in attachment to immune effector cells. ... Bacteria initially adhere to ciliated epithelial cells in the nasopharynx, and this interaction with epithelial cells is ... Tracheal cytotoxin itself is able to reproduce paralysis of the ciliary escalator, inhibition of DNA synthesis in epithelial ... van den Akker W (1997). "Bordetella bronchiseptica has a BvgAS-controlled cytotoxic effect upon interaction with epithelial ...
Sea louse
Sea lice cause physical and enzymatic damage at their sites of attachment and feeding, which results in abrasion-like lesions ... In contrast, coho and pink salmon show strong tissue responses to L. salmonis characterized by epithelial hyperplasia and ... Little evidence exists of host tissue responses in Atlantic salmon at the sites of feeding and attachment, regardless of the ... Sea-lice infection causes a generalized chronic stress response in fish since feeding and attachment cause changes in the mucus ...
Cadherin-1
... and suspended lens epithelial cells in it. He observed that cells suspended in the CM media had delayed attachment compared to ... E-cadherin has been found to have a role in epithelial morphogenesis and branching, such as during the formation of epithelial ... Instead, it appears stratified epithelial buds are generated by the clefting of one original epithelial cell cluster. ... E-cadherin level changes in EMT (epithelial-mesenchymal transition) and MET (mesenchymal-epithelial transition). E-cadherin ...
Thyroglobulin
The colloid is subsequently cleaved by proteases to release thyroglobulin from its T3 and T4 attachments. The active forms of ... the colloid is endocytosed from the follicular lumen into the surrounding thyroid follicular epithelial cells. ...
Porphyromonas gingivalis
P. gingivalis invades gingival epithelial cells in high numbers, in which case both bacteria and epithelial cells survive for ... They have a role in initial attachment and organization of biofilms, as they act as adhesins that mediate invasion and ... P. gingivalis outer membrane vesicles were found to be necessary for the invasion of epithelial cells of Tannerella forsythia. ... Fimbriae are appendages involved in cellular attachment and greatly contribute to virulence and are found on many Gram-negative ...
List of periodontal diseases
clinical attachment loss can be used to determine the severity of the condition, where 1-2mm is slight, 3-4mm is moderate and ... It is in the established lesion that epithelial proliferation and apical migration begin. In health, the junctional epithelium ... Loss of attachment may progress despite good oral hygiene and in the absence of risk factors such as smoking. Aggressive ... The defining feature of periodontitis is connective tissue attachment loss which may manifest as deepening of periodontal ...
Hemicentin 1
... organizes epithelial and other cell attachments into oriented line-shaped junctions". Development. 128 (6): 883-94. doi:10.1242 ...
Vaginal flora
... and their pili act as ligands for attachment to receptors of vaginal epithelial cells. The limited number of Lactobacillus spp ... Moreover, lactobacilli normally help to prevent long-term colonization of the vagina by adhering to vaginal epithelial cells. ...
Junctional epithelium
... and is stopped by the epithelial attachment (EA). However, the probing depth of the gingival sulcus may be considerably ... The attachment of the JE to the tooth surface can occur on enamel, cementum, or dentin. The position of the EA on the tooth ... Lysosomes are also found in large numbers in JE epithelial cells; enzymes contained within these lysosomes participate in the ... These superficial, or suprabasal, epithelial cells of the JE provide the hemidesmosomes and an internal basal lamina that ...
CD155
Its normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The external ... domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with ...
Ileum
In turn, the epithelial cells that line these villi possess even larger numbers of microvilli. Therefore, the ileum has an ... extremely large surface area both for the adsorption (attachment) of enzyme molecules and for the absorption of products of ... These enzymes are present in the cytoplasm of the epithelial cells. The villi contain large numbers of capillaries that take ...
Wound healing
Epithelial cells climb over one another in order to migrate. This growing sheet of epithelial cells is often called the ... In addition to providing support for fibroblast and endothelial cell attachment, biodegradable scaffolds inhibit wound ... However, epithelial cells require viable tissue to migrate across, so if the wound is deep it must first be filled with ... Epithelial cells have the ability to phagocytize debris such as dead tissue and bacterial matter that would otherwise obstruct ...
Beta-glucan
... implications for microbial attachment and oral vaccine targeting". The Journal of Experimental Medicine. 184 (3): 1045-1059. ... "Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: ...
Immunoglobulin A
... by sterically hindering attachment to epithelial cells, and by immune exclusion. Immune exclusion is a process of agglutinating ... It binds to the pIgR on the basolateral surface of epithelial cells, and is taken up into the cell via endocytosis. The ... The oligosaccharide chains of the component of IgA can associate with the mucus layer that sits atop epithelial cells. Since ... In this way, a barrier capable of neutralizing threats before they reach the epithelial cells is formed.[citation needed] ...
Transitional epithelium
All transitional epithelial cells are covered in microvilli and a fibrillar mucous coat. The epithelium contains many intimate ... The tonofilaments play a role in the attachment of the basal layer to the basement membrane via desmosomes. The intermediate ... This tissue consists of multiple layers of epithelial cells which can contract and expand in order to adapt to the degree of ... Carcinoma is a type of cancer that occurs in epithelial cells. Transitional cell carcinoma is the leading type of bladder ...
Head and neck anatomy
These include epithelial tissues (epithelium), connective tissues, (ligaments and bone), muscle tissue and nervous tissue. ... all of the support membranes of the dental structures surround and support the teeth such as the gums and the attachment ...
Retinol-binding protein
RBP mRNA was localized to epithelial cells of the chorion, allantois, and amnion at day 45 of pregnancy. Lastly, RBP mRNA was ... detected in the cotyledons, the fetal contribution to the placenta and the site of attachment to the uterine epithelium for ...
Acute Pyelonephritis: Practice Essentials, Background, Pathophysiology
Epithelial attachment and inflammatory response. Evidence suggests that the pathogenesis of pyelonephritis takes a 2-step path ... Other important factors are the flushing action of urine flow in the ureter and bladder, the inhibition of attachment of type 1 ... They also allow the bacteria to remain in close proximity to the epithelial cell, enhancing the activity of other VFs. ... Mannose-resistant adhesins permit the bacteria to attach to epithelial cells, thereby resisting the cleansing action of urine ...
Regeneration of rabbit cornea following excimer laser photorefractive keratectomy: a study on gap junctions, epithelial...
Epithelial Attachment / physiology* * ErbB Receptors / metabolism* * Gap Junctions / physiology* * Hemidesmosomes / physiology ... At this time, basal epithelial cells at the limbal region, adjacent to the wound and those migrating over the wounded area all ... Mitotic activity in the migrating corneal epithelial cells is also a novel finding which is probably the sign of the excessive ... In resting cornea two isotypes of gap junctions, confined to different regions in the same basal epithelial cells, were ...
The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of...
The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of ... The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of ... The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of ... The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of ...
Table - Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals - Volume 18, Number 5-May 2012 - Emerging...
... ciliated epithelial cell; ND, not determined; I, type I pneumocytes; II, type II pneumocytes.. †Virus attachment to submucosal ... Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals Antonio J. Ramis. , Debby van Riel, Marco W.G van de ... Attachment of mammal and human avian influenza viruses to respiratory tracts of 4 marine mammals* ... Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals. ...
Scientific publications | IGBMC
Inhibition of Escherichia coli O157:H7 attachment by interactions between lactic acid bacteria and intestinal epithelial cells<...
H7 attachment to epithelial cells. In the current study, the attachment of E. coli O157:H7 to HT-29 intestinal epithelial cells ... H7 attachment to epithelial cells. In the current study, the attachment of E. coli O157:H7 to HT-29 intestinal epithelial cells ... H7 attachment to epithelial cells. In the current study, the attachment of E. coli O157:H7 to HT-29 intestinal epithelial cells ... H7 attachment to epithelial cells. In the current study, the attachment of E. coli O157:H7 to HT-29 intestinal epithelial cells ...
Effect of urine fractionation on attachment of calcium oxalate crystals to renal epithelial cells: implications for studying...
Grover P, Thurgood L, Ryall R. Effect of urine fractionation on attachment of calcium oxalate crystals to renal epithelial ... Effect of urine fractionation on attachment of calcium oxalate crystals to renal epithelial cells: implications for studying ... Effect of urine fractionation on attachment of calcium oxalate crystals to renal epithelial cells: implications for studying ... title = "Effect of urine fractionation on attachment of calcium oxalate crystals to renal epithelial cells: implications for ...
Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated...
Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated ... Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated ... Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated ... Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated ...
Cancers | Free Full-Text | Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for...
During EMT, epithelial cells undergo a cellular transformation as manifested by cell elongation, migration, and invasion, ... a vital cellular process during metastasis is the transformation of epithelial cells towards motile mesenchymal cells called ... the epithelial to mesenchymal transition (EMT). The cytoskeleton is an active network of three intracellular filaments: actin ... Epithelial cells are tightly secured to the basement membrane via highly specialized integrin-mediated attachment structures. ...
Leukocyte-Mediated Epithelial Injury in Ozone-Exposed Rat Lung | Health Effects Institute
AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and...
Since epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cell traits are important for cancer onset ... We have shown that AUF1 induces EMT and stemness in breast epithelial cells via stabilization of the SNAIL1 and TWIST1 mRNAs, ... Ectopic expression of AUF1 also promoted stemness in mammary epithelial cells, and thereby increased the proportion of cancer ... To this end, MCF10A-ORF/MCF10A-C and MCF7-C/MCF7-ORF cells were plated at low density into ultra-low attachment plates in the ...
Membrane vesicle trafficking - Wikipedia
"Characteristics of Helicobacter pylori attachment to human primary antral epithelial cells". Microbes and Infection. 2 (14): ... These vesicles were suspected to promote bacterial adhesion to the host epithelial cell surface. Their role in invasion of ... Role of OMVs in Helicobacter pylori infection of human primary antral epithelial cells, as model that closely resembles human ... Salmonella OMVs were also shown to have direct role in invasion of chicken ileal epithelial cells in vivo in the year, 1993 ( ...
Dental History (1982-1984)
The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble...
Stripes of βPS-integrin staining are muscle attachment sites. Scale bar: 10 μm. ... We propose that, during DC, the LE membrane undergoes an epithelial-to-mesenchymal-like transition to initiate epithelial sheet ... followed by a mesenchymal-to-epithelial-like transition as the epithelial sheets meet up and restore cell-cell adhesion. This ... When the opposing epithelial flanks meet up, events can be reversed with Pak recruiting the Scrib complex to the lateral ...
Probiotics may be beneficial in COVID-19 treatment
... or to the epithelial surface itself. This prevents the attachment of the virus to the epithelial cell receptors, often by ... B ) Binding of probiotic bacteria to the epithelial surface can cause steric hindrance and block the viruss attachment to the ... Secondly, they improve the function of the gut epithelial barrier and correct dysbiosis, along with the release of multiple ... E ) Upon virus attack in epithelial cells, probiotics mediate their antiviral effects by eliciting immune responses by ...
Reproduction of the Antitumor Effect of Cisplatin and Cetuximab Using a Three-dimensional Spheroid Model in Oral Cancer
E-cadherin is a key molecule in the maintenance of epithelial integrity, is involved in the regulatory mechanisms of epithelial ... 3D spheroids were cultured in 96-well ultra-low attachment (ULA) plate (#7007; Corning, NY). 1.0×105 cells were seeded in each ... Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma: Characterization in a 3D-cell culture model. World J ... Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res. 2006;66: ...
Virology and Molecular Epidemiology of Respiratory Syncytial Virus (RSV) | IntechOpen
The G protein initiates attachment of the virus to the epithelial cell. The virus fuses with the epithelial cell membrane and ... The outer envelope is lined internally with matrix (M) protein and is spiked externally with fusion (F) and attachment (G) ... The infection results in the destruction of the epithelial cells of the upper respiratory tract. Exposure to RSV triggers ... Othumpangat S, Gibson L, Samsell L, Piedimonte G. NGF is an essential survival factor for bronchial epithelial cells during ...
Honey! Natural Treatment for Gum Disease
The effect of honey on the epithelial attachment. Journal of the Missouri Dental Association 58 (2):15-19, 44.. ... The stimulatory action of honey on the growth of granulation tissue and epithelial cells would also be of benefit in hastening ... honey to treat periodontal disease would be its well established stimulation of the growth of granulation tissue and epithelial ...
Recurrent Urinary Tract Infections - StatPearls - NCBI Bookshelf
Frontiers | Design and adsorption of modular engineered proteins to prepare customized, neuron-compatible coatings
El-Ghannam, A., Starr, L., and Jones, J. (1998). Laminin-5 coating enhances epithelial cell attachment, spreading, and ... neuronal attachment through interaction with an hypothesized neuronal receptor homologous to one identified in epithelial cells ... covalent molecule attachment (Huber et al., 1998 ; Massia et al., 2004 ), self-assembling monolayers (Pakalns et al., 1999 ), ... Modification of glassy carbon surfaces with synthetic laminin-derived peptides for nerve cell attachment and neurite growth. J ...
Study protocol for economic evaluation of probiotic intervention for prevention of neonatal sepsis in 0-2-month old low-birth...
Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma
Activated Lactoferrin-A New Approach to Meat Safety - IFT.org
Activated form of natural antimicrobial improves safety of beef and poultry by preventing attachment and growth of bacteria. ... Microbial attachment to epithelial mucosa or biosurfaces is the initial step in the pathogenesis of many infections as well as ... such as the inhibition of microbial attachment to sub-epithelial matrix proteins and detachment of bacteria from mucosal ... Activated form of natural antimicrobial improves safety of beef and poultry by preventing attachment and growth of bacteria.. ...
Publications | Prof. Anat Yarden
Cultured epithelial cells interact massively rapidly and stereospecifically with the {011} faces of calcium (R,R)-tartrate ... Attachment is however not followed by normal cell spreading and development of focal adhesions, but results in massive cell ... This implies that the deprivation of proper extracellular matrix (ECM)-receptor contacts of substrate-attached epithelial cells ... structure which is responsible for the attachment of actin filaments to the plasma membrane. Vinculin consists of 1066 amino ...
The Effects of Carbon and Gold Ion Implanted Surfaces on Neuronal Stem Cells' Functions | OMICS International
Gould TR, Brunette DM, Westsury L (1981) The attachment mechanism of epithelial cells to titanium in vitro. J Periodontal Res ... A significant increase of cell attachment was observed with respect to time (p,0.05) and the maximum cell attachment was ... Focal attachments have 10-15 nm distance between the cell membrane and the material surface and they are tight connections. ... Polystyrene Petri dishes were picked as they were the most used in vitro surfaces for cell attachment. Carbon (C) and Gold (Au ...
3D Cell Culture
Poly-L-Lysine Cell Attachment Protocol. Adhere cells to solid substrates using poly-lysine, which enhances electrostatic ... Highly characterized cryopreserved human colonic organoids and a step-by-step organoid culture protocol for epithelial ... Spheroid culture can be achieved in diverse environments including low-attachment microplates, bioreactors, and microfluidics ...
Dental Cleaning and Home Care Products - WSAVA2007 - VIN
The depth is read as the measurement from the epithelial attachment to the gingival margin. If the gingiva is recessed, the ... as you careful insert the probe into the sulcus between the crown and the gingiva down to the level of epithelial attachment. ... measurement should be made from the epithelial attachment to the level of the cementoenamel junction (CEJ). Any abnormal ...
Systemic Endothelial Support GLYCERITE - Woodland Essence
Use of the carbon dioxide laser in guided tissue-regeneration wound healing in the beagle dog | (1996) | Rossmann | ...
This epithelial proliferation apically interferes with the establishment of the new connective tissue attachment to the root ... This experimental design allowed histologic study of the new attachment obtained in defects treated with flap debridement with ... The results showed significant amounts of new attachment obtained from all four treatment modalities with no statistically ... ligament and alveolar bone to repopulate the treated root surface has shown the ability to obtain periodontal new attachment. ...