A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)
A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic (i.e., occurring secondary to known disease processes such as infections, hypoxic-ischemic injuries, trauma, etc.).
Drugs used to prevent SEIZURES or reduce their severity.
A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8)
A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), and generalized major motor seizures (see EPILEPSY, TONIC-CLONIC). The myoclonic episodes tend to occur shortly after awakening. Seizures tend to be aggravated by sleep deprivation and alcohol consumption. Hereditary and sporadic forms have been identified. (From Adams et al., Principles of Neurology, 6th ed, p323)
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)
A localization-related (focal) form of epilepsy characterized by seizures which arise in the FRONTAL LOBE. A variety of clinical syndromes exist depending on the exact location of the seizure focus. Frontal lobe seizures may be idiopathic (cryptogenic) or caused by an identifiable disease process such as traumatic injuries, neoplasms, or other macroscopic or microscopic lesions of the frontal lobes (symptomatic frontal lobe seizures). (From Adams et al., Principles of Neurology, 6th ed, pp318-9)
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder."
An autosomal dominant inherited partial epilepsy syndrome with onset between age 3 and 13 years. Seizures are characterized by PARESTHESIA and tonic or clonic activity of the lower face associated with drooling and dysarthria. In most cases, affected children are neurologically and developmentally normal. (From Epilepsia 1998 39;Suppl 4:S32-S41)
Recurrent seizures causally related to CRANIOCEREBRAL TRAUMA. Seizure onset may be immediate but is typically delayed for several days after the injury and may not occur for up to two years. The majority of seizures have a focal onset that correlates clinically with the site of brain injury. Cerebral cortex injuries caused by a penetrating foreign object (CRANIOCEREBRAL TRAUMA, PENETRATING) are more likely than closed head injuries (HEAD INJURIES, CLOSED) to be associated with epilepsy. Concussive convulsions are nonepileptic phenomena that occur immediately after head injury and are characterized by tonic and clonic movements. (From Rev Neurol 1998 Feb;26(150):256-261; Sports Med 1998 Feb;25(2):131-6)
A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)
An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their three-dimensional structure is similar.
A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
A neurosurgical procedure that removes the anterior TEMPORAL LOBE including the medial temporal structures of CEREBRAL CORTEX; AMYGDALA; HIPPOCAMPUS; and the adjacent PARAHIPPOCAMPAL GYRUS. This procedure is generally used for the treatment of intractable temporal epilepsy (EPILEPSY, TEMPORAL LOBE).
A compound suggested to be both a nootropic and a neuroprotective agent.
A heterogeneous group of primarily familial disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intellectual deterioration, and neuronal degeneration. These include LAFORA DISEASE; MERRF SYNDROME; NEURONAL CEROID-LIPOFUSCINOSIS; sialidosis (see MUCOLIPIDOSES), and UNVERRICHT-LUNDBORG SYNDROME.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.
Surgery performed on the nervous system or its parts.
Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
Treatment of chronic, severe and intractable psychiatric disorders by surgical removal or interruption of certain areas or pathways in the brain, especially in the prefrontal lobes.
A condition marked by recurrent seizures that occur during the first 4-6 weeks of life despite an otherwise benign neonatal course. Autosomal dominant familial and sporadic forms have been identified. Seizures generally consist of brief episodes of tonic posturing and other movements, apnea, eye deviations, and blood pressure fluctuations. These tend to remit after the 6th week of life. The risk of developing epilepsy at an older age is moderately increased in the familial form of this disorder. (Neurologia 1996 Feb;11(2):51-5)
A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.
The repeated weak excitation of brain structures, that progressively increases sensitivity to the same stimulation. Over time, this can lower the threshold required to trigger seizures.
An adjunctive treatment for PARTIAL EPILEPSY and refractory DEPRESSION that delivers electrical impulses to the brain via the VAGUS NERVE. A battery implanted under the skin supplies the energy.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
The storing or preserving of video signals for television to be played back later via a transmitter or receiver. Recordings may be made on magnetic tape or discs (VIDEODISC RECORDING).
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID. (From Martindale The Extra Pharmacopoeia, 31st ed)
An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
A surgical specialty concerned with the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system.
Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools.
Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.
A disorder characterized by recurrent localized paroxysmal discharges of cerebral neurons that give rise to seizures that have motor manifestations. The majority of partial motor seizures originate in the FRONTAL LOBE (see also EPILEPSY, FRONTAL LOBE). Motor seizures may manifest as tonic or clonic movements involving the face, one limb or one side of the body. A variety of more complex patterns of movement, including abnormal posturing of extremities, may also occur.
The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)
Registered nurses who hold Master's degrees in nursing with an emphasis in clinical nursing and who function independently in coordinating plans for patient care.
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
GRAY MATTER situated above the GYRUS HIPPOCAMPI. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called GRANULE CELLS, whose AXONS pass through the polymorphic layer ending on the DENDRITES of PYRAMIDAL CELLS in the hippocampus.
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
A variety of neuromuscular conditions resulting from MUTATIONS in ION CHANNELS manifesting as episodes of EPILEPSY; HEADACHE DISORDERS; and DYSKINESIAS.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.
A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Dominance of one cerebral hemisphere over the other in cerebral functions.
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
The measurement of magnetic fields over the head generated by electric currents in the brain. As in any electrical conductor, electric fields in the brain are accompanied by orthogonal magnetic fields. The measurement of these fields provides information about the localization of brain activity which is complementary to that provided by ELECTROENCEPHALOGRAPHY. Magnetoencephalography may be used alone or together with electroencephalography, for measurement of spontaneous or evoked activity, and for research or clinical purposes.
A characteristic symptom complex.
An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
An act of employing sorcery (the use of power gained from the assistance or control of spirits), especially with malevolent intent, and the exercise of supernatural powers and alleged intercourse with the devil or a familiar. (From Webster, 3d ed)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Axons of certain cells in the DENTATE GYRUS. They project to the polymorphic layer of the dentate gyrus and to the proximal dendrites of PYRAMIDAL CELLS of the HIPPOCAMPUS. These mossy fibers should not be confused with mossy fibers that are cerebellar afferents (see NERVE FIBERS).
Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
The largest portion of the CEREBRAL CORTEX in which the NEURONS are arranged in six layers in the mammalian brain: molecular, external granular, external pyramidal, internal granular, internal pyramidal and multiform layers.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes. (1/4971)

Otx1 and Otx2, two murine homologs of the Drosophila orthodenticle (otd) gene, show a limited amino acid sequence divergence. Their embryonic expression patterns overlap in spatial and temporal profiles with two major exceptions: until 8 days post coitum (d.p.c. ) only Otx2 is expressed in gastrulating embryos, and from 11 d.p.c. onwards only Otx1 is transcribed within the dorsal telencephalon. Otx1 null mice exhibit spontaneous epileptic seizures and multiple abnormalities affecting primarily the dorsal telencephalic cortex and components of the acoustic and visual sense organs. Otx2 null mice show heavy gastrulation abnormalities and lack the rostral neuroectoderm corresponding to the forebrain, midbrain and rostral hindbrain. In order to define whether these contrasting phenotypes reflect differences in expression pattern or coding sequence of Otx1 and Otx2 genes, we replaced Otx1 with a human Otx2 (hOtx2) full-coding cDNA. Interestingly, homozygous mutant mice (hOtx2(1)/hOtx2(1)) fully rescued epilepsy and corticogenesis abnormalities and showed a significant improvement of mesencephalon, cerebellum, eye and lachrymal gland defects. In contrast, the lateral semicircular canal of the inner ear was never recovered, strongly supporting an Otx1-specific requirement for the specification of this structure. These data indicate an extended functional homology between OTX1 and OTX2 proteins and provide evidence that, with the exception of the inner ear, in Otx1 and Otx2 null mice contrasting phenotypes stem from differences in expression patterns rather than in amino acid sequences.  (+info)

Characterization of nodular neuronal heterotopia in children. (2/4971)

Neuronal heterotopia are seen in various pathologies and are associated with intractable epilepsy. We examined brain tissue from four children with subcortical or periventricular nodular heterotopia of different aetiologies: one with severe epilepsy following focal brain trauma at 17 weeks gestation, one with hemimegalencephaly and intractable epilepsy, one with focal cortical dysplasia and intractable epilepsy, and one dysmorphic term infant with associated hydrocephalus and polymicrogyria. The connectivity of nodules was investigated using histological and carbocyanine dye (DiI) tracing techniques. DiI crystal placement adjacent to heterotopic nodules revealed numerous DiI-labelled fibres within a 2-3 mm radius of the crystals. Although we observed labelled fibres closely surrounding nodules, the majority did not penetrate them. Placement of DiI crystals within nodules also identified a limited number of projections out of the nodules and in one case there was evidence for connectivity between adjacent nodules. The cellular and neurochemical composition of nodules was also examined using immunohistochemistry for calretinin and neuropeptide Y (NPY), which are normally expressed in GABAergic cortical interneurons. Within heterotopic nodules from all cases, numerous calretinin-positive neurons were identified, along with a few cell bodies and many processes positive for NPY. Calretinin-positive neurons within nodules were less morphologically complex than those in the cortex, which may reflect incomplete differentiation into an inhibitory neuronal phenotype. There were also abnormal clusters of calretinin-positive cells in the overlying cortical plate, indicating that the migratory defect which produces heterotopic nodules also affects development of the cortex itself. Thus, heterotopic nodules consisting of multiple neuronal cell types are associated with malformation in the overlying cortical plate, and have limited connectivity with other brain regions. This abnormal development of connectivity may affect neuronal maturation and consequently the balance of excitation and inhibition in neuronal circuits, leading to their epileptogenic potential.  (+info)

Oligodendroglial vacuolar degeneration in the bilateral motor cortices and astrocytosis in epileptic beagle dogs. (3/4971)

We performed a pathologic examination of the brains of three dogs in an epileptic beagle colony. Histologically, all the cases had diffuse astrocytosis in the cerebral cortex and basal ganglia as well as the hippocampus, whereas they showed acute nerve cell change in the hippocampus and some other areas of the cerebrum. One of these animals showed laminar myelin pallor associated with the presence of many vacuoles in the IV to VI layers of the bilateral motor cortices. Most of the vacuoles contained fine granules stained with luxol-fast-blue stain. Ultrastructural examination revealed that some oligodendrocytes and perineuronal satellite oligodendrocytes in the bilateral cerebral motor cortices of the two affected dogs had many vacuoles surrounded by myelin-like lamellar structures. These findings suggest a possibility that astrocytosis in the cerebrum and vacuolar degeneration of oligodendrocytes in the cerebral motor cortex may be, at least in part, related to the occurrence or development of seizures.  (+info)

Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic. (4/4971)

The occurrence of epileptic seizures during onchocercal infestation has been suspected. Epidemiologic studies are necessary to confirm the relation between onchocerciasis and epilepsy. A matched case-control study was conducted in dispensaries of three northwestern towns of the Central African Republic. Each epileptic case was matched against two nonepileptic controls on the six criteria of sex, age (+/-5 years), residence, treatment with ivermectin, date of last ivermectin dose, and the number of ivermectin doses. Onchocerciasis was defined as at least one microfilaria observed in iliac crest skin snip biopsy. A total of 561 subjects (187 cases and 374 controls) were included in the study. Of the epileptics, 39.6% had onchocerciasis, as did 35.8% of the controls. The mean dermal microfilarial load was 26 microfilariae per mg of skin (standard deviation, 42) in the epileptics and 24 microfilariae per mg of skin (standard deviation, 48) in the controls. This matched case-control study found some relation (odds ratio = 1.21, 95% confidence interval 0.81-1.80), although it was nonstatistically significant.  (+info)

Adjunctive therapy in epilepsy: a cost-effectiveness comparison of two AEDs. (5/4971)

The objective of this study was to compare the relative cost-effectiveness of two AEDs by a prospective clinical audit. Patients starting on the adjunctive therapies lamotrigine and topiramate were recruited from the out-patient epilepsy clinics at Queen Square. Three interview were scheduled: baseline; three months follow-up and six months from baseline. Of the 81 patients recruited, a total of 73 patients completed all three interviews. An intention to treat analysis was performed on the data. Seizure severity and frequency were assessed using the National Hospital Seizure Severity Scale. Side-effects, adverse events and reasons for stopping medication were also recorded. At the third interview, a total of 47/73 (64%) were still on the prescribed adjunctive drug. Outcome was assessed by two methods: the > 50% seizure reduction cited in the literature and a more stringent assessment of patient 'satisfaction' which we defined operationally on clinical criteria. Using this definition, a total of 10/73 (14%) patients were 'satisfied'. The relative costs of starting patients on each of the two AEDs were calculated, both drug costs and the costs of adverse events (the latter were defined as events requiring urgent medical attention). The costs of the two drugs were compared. A number of methodological issues relating to cost comparison are discussed. Outcome and pharmaco-economic studies need to assess more than reduction in number of seizures. They should take into account variables important for quality of life including side-effects and adverse events.  (+info)

Willingness to pay: a feasible method for assessing treatment benefits in epilepsy? (6/4971)

Contingent valuation using willingness to pay (WTP) is one of the methods available for assessing the value of a new technology or treatment for a disease in monetary terms. Experience with this method is lacking in epilepsy. The objectives of this study were to assess the acceptability of the WTP method in epilepsy, the level of the responses, and to investigate its validity by comparison with other non-monetary preference measures. Among 397 patients with epilepsy responding to a comprehensive questionnaire, 82 were randomly selected for an interview. They were asked about their WTP for an imaginary new technology which could permanently cure their epilepsy. Fifty-nine patients participated and 57 completed the interview (32 women; mean age 44 years), the majority with well-controlled epilepsy. The patients indicated a median WTP of Norwegian Kroner (NOK) 150,000 (USD 20,000; GBP 11,800), interquartile range NOK 50,000-350,000 (USD 6, 667-46, 667; GBP 3,937-27,559) for this cure. Non-response was low, indicating high acceptability of this method. There was little association between WTP and other preference measures; the Spearman rank correlation coefficient was -0.09 and -0.12 with time trade-off and standard gamble respectively, questioning the validity of this method.  (+info)

Outcome of pregnancies in epileptic women: a study in Saudi Arabia. (7/4971)

We studied the outcome of 79 pregnancies in 44 Saudi women who had epilepsy. Their mean age was 28+/-6.5 years and the number of pregnancies studied varied from one to six. Nineteen subjects had generalized seizures, 16 had partial seizures and nine were unclassified. The commonest drug prescribed was carbamazepine and the majority of the women (61%) were on monotherapy. The seizures were controlled in 53 pregnancies (67%). Spontaneous vertex deliveries were the commonest. The indications for intervention by lower segment Caesarean section, forceps or ventouse were foetal distress, pre-eclamptic toxaemia (PET), eclampsia, breech presentation and prolonged labour. The most frequent adverse outcome in the babies was low birth weight (<2.5 kg) in nine pregnancies. The frequency of congenital malformation was 2.5%. Low birth weight was associated with prematurity, PET, congenital malformation and polytherapy. Avoidance of polytherapy appears to be the most feasible intervention in reducing the frequency of low birth-weight children by epileptic mothers.  (+info)

Information exchange in an epilepsy forum on the World Wide Web. (8/4971)

The Partners Healthcare Epilepsy Service hosts an epilepsy 'Webforum'. In this paper, we describe our observations regarding who uses it, what kind of information is exchanged, how much misinformation is present and how we can better serve our patients. We examined a sample of 155 posts to the forum and 342 responses to those posts. The individual making the post and the type of questions were categorized. We also determined whether any information was objectively inaccurate. The principal users were care-givers (49%) and patients (34%). Eighty percent of the primary posts were questions. Answers were given largely by patients (38%) and care-givers (34%). The most commonly asked questions were about treatment options (31%) and the natural history of the illness (28%). In 20% of the questions, the user incidentally remarked that a health-care provider had not met their information needs. Six percent of the information was objectively inaccurate. The Web can serve as an effective means for the exchange of information between individuals with a common medical condition. We found that a small amount of misinformation is exchanged and that health-care providers are sometimes perceived as unable or unwilling to supply important health-related information.  (+info)

Abstract Regarding efficacy of new antiepileptic drugs (AEDs) for seizure control, there are three important clinical questions.Download and Read New Antiepileptic Drugs Epilepsy Research Supplement No 3 New Antiepileptic Drugs Epilepsy Research Supplement No 3 It sounds good when knowing the.Several studies show drugs used to treat AEDS reduce bone density, increase risk of fracture, especially for the up to 50% of users unresponsive to AEDS.Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy. new AEDs with many of the non-AED drugs.AMR has developed set of analyst tools and data models to supplement.. Research identifies protein that could help patients respond more positively to epilepsy drug therapies.Seizures and epilepsy: Hope through research. for treatment of drug-resistant epilepsy ...
TY - JOUR. T1 - Understanding of and attitudes toward epilepsy among the urban Chinese population in Malaysia. AU - Hasan, S. S.. AU - Alen, Y. K S. AU - Wayne, W. G W. AU - Ahmadi, K.. AU - Anwar, M.. AU - Goh, G. K.. PY - 2010/4. Y1 - 2010/4. N2 - Introduction: People with epilepsy are socially discriminated against on the grounds of widespread negative public attitudes, misunderstandings and defensive behaviour. The primary purpose of this study was to evaluate the public understanding of and attitudes toward epilepsy among the Chinese population in Malaysia. Methods: A validated, self-administered questionnaire comprising 23 questions was utilised to evaluate the understanding of and attitudes toward epilepsy among randomly approached respondents from the Chinese population living in the urban areas of Penang, Klang Valley, Kuala Lumpur and Sibu in Malaysia. Results: Out of 1,000 people approached, 697 (69.7 percent) respondents agreed to participate in the study. When asked whether people ...
The Yale Epilepsy Research Retreat is a two day educational meeting in which clinical and basic science researchers from Yale and collaborators from other institutions will discuss the latest advances in cutting-edge epilepsy research. In addition, we are inviting an outstanding leader in epilepsy research, well versed in both human and basic epilepsy research, to speak at the Retreat, provide feedback and guidance, and serve as an external moderator and reviewer for the research program. The Retreat will consist of investigator slide presentations, poster sessions, and break-out discussions on new research approaches and collaborations. The Third Annual Yale comprehensive Epilepsy Research Retreat took place on April 3-4, 2014 at the Madison Beach Hotel in Madison, CT. The 2014 Research Retreat Agenda ...
Epilepsy is a common disease of the brain, occurring in roughly 1% of all people, and although repeated epileptic seizures are its clinical hallmark, epilepsy is not just a medical phenomenon, but a social construct, with cultural, political, and financial consequences. People with epilepsy are exposed to stigma and burdened with disadvantages which can be far reaching. There are indeed many remedies, but no cure. This book provides a biography of modern epilepsy in the form of a brief and selective narrative of some of the important developments in medical and social epilepsy research, with its many ups and downs, over the period since 1860. Its anatomy of modern epilepsy in eight chapters is, inevitably in this short book, selective, and intentionally provocative. The books main objective is to provide both a survey of the evolution of epilepsy and its treatment in the post-Jacksonian era, and also a critical look at where we are today and how we got there. This book tries to make an effort to
In Kentucky and Southern Indiana alone, more than 90,000 people have epilepsy, demonstrating a vital need for a comprehensive epilepsy team.. Epilepsy is the third-most common neurological disorder in the United States after Alzheimers disease and stroke. Between 30 percent and 40 percent of the 2.7 million Americans diagnosed with a seizure disorder have seizures that are not well controlled by medication. Others have their epilepsy untreated or misdiagnosed.. That is why the University of Louisville Hospital Epilepsy Center is such a critical resource for our community and state. Our center is one of only a few Level IV Epilepsy Centers in the region, meaning we have the ability to do everything from diagnosing epilepsy to performing surgery when appropriate.. Our Epilepsy Center has a state-of-the-art monitoring unit and dedicated nurses and physicians who have the experience and expertise needed to provide comprehensive epilepsy services.. ...
TY - JOUR. T1 - Classifications and epidemiologic considerations of epileptic seizures and epilepsy. AU - So, E. L.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - Epileptic disorders are some of the most common neurologic conditions. The lifetime risk of experiencing an epileptic seizure is as high as 8%. The manifestations of epileptic disorders are also quite protean. Clinical evaluation of seizure disorders requires a clear understanding of the classifications and the terminology used. This article defines and classifies epileptic seizures, epilepsy, and epilepsy syndromes. The epidemiologic profiles of first unprovoked seizure and epilepsy are also described.. AB - Epileptic disorders are some of the most common neurologic conditions. The lifetime risk of experiencing an epileptic seizure is as high as 8%. The manifestations of epileptic disorders are also quite protean. Clinical evaluation of seizure disorders requires a clear understanding of the classifications and the terminology used. This article ...
Since the development of the 2007 Epilepsy Research Benchmarks, remarkable strides have been made toward understanding the causes of epilepsy and epileptogenesis, developing new and improved treatments, and delineating factors that contribute to comorbidities associated with epilepsy. The Epilepsy Research Benchmarks Stewards have selected the following research advances from
New Hanover Regional Medical Center was recently accredited by the National Association of Epilepsy Centers as a level 3 epilepsy center. Level 3 epilepsy centers have the professional expertise and facilities to provide the highest level medical evaluation and treatment for patients with complex epilepsy.. A level 3 center provides the basic range of medical, neuropsychological, and psychosocial services needed to treat patients with refractory epilepsy. Level 3 epilepsy centers provide basic neurodiagnostic evaluations, as well as basic medical, neuropsychological, and psychosocial services. Some level 3 centers offer noninvasive evaluation for epilepsy surgery, straight-forward resective epilepsy surgery, and implantation of the vagus nerve stimulator. These centers do not perform intracranial evaluations or other more complex epilepsy surgery.. ...
Release: Nov. 13, 2000. UI Health Care specialist to lead online chat on epilepsy Nov. 14. IOWA CITY, Iowa -- Mark A. Granner, M.D., an associate professor of clinical neurology and director of the epilepsy monitoring unit with University of Iowa Health Care, will lead an hour-long, online question-and-answer discussion on epilepsy with a nationwide audience from 3:30 to 4:30 p.m. Tuesday, Nov.14.. The online chat will be hosted by AmericasDoctor.com and can be accessed by entering through the www.AmericasDoctor.com home page under Upcoming Events.. Epilepsy is the second most common neurological condition after migraine. Today, epilepsy can in most cases be controlled with the correct medical treatment. However, living with epilepsy has its problems, and special education and care are required for the person with epilepsy to lead an active, healthy, and satisfying life. Granner will discuss selected medical and social issues related with epilepsy and will answer questions from the ...
Most people with epilepsy CAN DO the same things that people without epilepsy can do. However, some people with frequent seizures may not be able to work, drive, or may have problems in other parts of their life.. * People with epilepsy CAN handle jobs with responsibility and stress. People with seizure disorders are found in all walks of life. They may work in business, government, the arts and all sorts of professions. If stress bothers their seizures, they may need to learn ways to manage stress at work. But everyone needs to learn how to cope with stress! There may be some types of jobs that people with epilepsy cant do because of possible safety problems. Otherwise, having epilepsy should not affect the type of job or responsibility that a person has.. * Even with todays medication, epilepsy CANNOT be cured. Epilepsy is a chronic medical problem that for many people can be successfully treated. Unfortunately, treatment doesnt work for everyone. AT LEAST 1 million people in the United ...
Patients living with epilepsy a complex seizure disorder face many challenges. Characterized by disabling seizures triggered by abnormal electrical activity in the brain cells, the disease can manifest itself through a range of symptoms, from minor physical signs and thought disturbances to traumatic physical convulsions. Several types of seizures are easy to control, and many patients are well enough between episodes to lead normal lives. However, about 30 percent of the estimated three million Americans with epilepsy suffer with persistent seizures.. In an outstanding validation of its commitment to improving the lives of patients with epilepsy, the NYU Winthrop Comprehensive Epilepsy Center has once again been recognized by the National Association of Epilepsy Centers (NAEC) as a Level 4 Epilepsy Center. Level 4 Epilepsy Centers have the professional expertise and facilities to provide the highest level medical and surgical evaluation and treatment for patients with complex epilepsy.. We at ...
Individuals with epilepsy who cannot be adequately controlled with anti-epileptic drugs, refractory epilepsy, may be suitable for surgical treatment following detailed assessment. This is a complex process and there are concerns over delays in referring refractory epilepsy patients for surgery and subsequent treatment. The aim of this study was to explore the different patient pathways, referral and surgical timeframes, and surgical and medical treatment options for refractory epilepsy patients referred to two Tertiary Epilepsy Clinics in New South Wales, Australia. Clinical records were reviewed for 50 patients attending the two clinics, in two large teaching hospitals (25 in Clinic 1; 25 in Clinic 2. A purpose-designed audit tool collected detailed aspects of outpatient consultations and treatment. Patients with refractory epilepsy with their first appointment in 2014 were reviewed for up to six visits until the end of 2016. Data collection included: patient demographics, type of epilepsy, drug
Epilepsy Research provides for publication of high quality articles in both basic and clinical epilepsy research, with a special emphasis on...
of neuroimaging. Unlike congresses of thematic societies, the AMIE does not focus on results of examinations and studies but on the underlying technical aspects.. The AMIE is a twin-event with the Summer School on Imaging (SuSIE 2020) which provides clinical lectures and hands-on-workshops on Imaging in Epilepsy, Epilepsy Surgery, Epilepsy Research and Cognitive Neurosciences.. The AMIE 2020 was intended to take place from September 14th to 16th, 2020 in Bochum, Germany. However, due to the current COVID-situation, the AMIE 2020 will be held exclusively online. We offer the following program for you:. AMIE Online Scientific Workshops: all organizers of scientific workshops planned for the 2020 AMIE are currently being invited to run publically accessible video conferences instead. Look at the program to be updated with regards to those workshops that will go online and their respective time slots.. AMIE Sponsored Workshops: Commercial AMIE partners have the option to offer online presentations ...
That Mans Epilepsy , download That Mans Epilepsy , Download dan Baca That Mans Epilepsy , Download Manhwa Batch That Mans Epilepsy , That Mans Epilepsy untuk HP , Android , Tablet dan lain sebagainya , That Mans Epilepsy Batch Sub indo Lengkap , That Mans Epilepsy Chapter 1 sampai selesai batch sub indo , That Mans Epilepsy Chapter 1 , chapter 2 , chapter 7 lengkap , Download Full Chapter Manhwa That Mans Epilepsy sub indo gratis , Download Batch That Mans Epilepsy SUB INDO GRATIS , download That Mans Epilepsy Manhwa , Manhua , Manga , Doujin , , download komik That Mans Epilepsy , komik That Mans Epilepsy , download manhwa batch , komik , Chapter Terbaru , download manhwa terbaru , download komik sub indo That Mans Epilepsy ...
Epilepsy affects people of any age, gender, and race or ethnicity. Years of uncontrolled epilepsy can lead to cognitive decline or death, and increases the burden of epilepsy on society by reducing the likelihood that epilepsy patients will lead a productive, independent life. Fortunately, a randomized controlled trial has shown that focal epilepsy surgery is more effective and less costly than medical therapy and results in increased quality-of-life.. Unfortunately, there is the notion that epilepsy surgery is under utilized and the average time between onset of seizures and surgery is 20 years. Promoting utilization of epilepsy surgery is a way to improve patients quality of life by ensuring that they are receiving the best possible care. To achieve this goal, a user-friendly tool has been developed and validated to assist physicians in identifying patients ≥5 years old with focal epilepsy who should be referred for a surgical evaluation. For more information on how the tool was developed, ...
Speaking in the lead up to Purple Day for Epilepsy Awareness (Tuesday 26 March), geneticist Professor Jozef Gecz says advances in DNA sequencing have been a huge leap forward in understanding epilepsy.. This, combined with the use of stem cells in laboratory research, will lead to further advances in epilepsy treatment, he says.. However, he cautions that the same technology has also helped to reveal that epilepsy is a far more complex condition than previously thought.. Scientists used to believe that epilepsy was just one condition, possibly with one main cause. But now we know it is a very complex series of neurological disorders - it is many epilepsies, instead of just one epilepsy, with multiple causes and various symptoms, says Professor Gecz, from the University of Adelaides School of Paediatrics and Reproductive Health.. Epilepsy is common, with up to 3% of the Australian population experiencing epilepsy at some stage in their lives. Genetic and environmental factors, and trauma, can ...
Epilepsy is one of the most common neurological disorders and has enormous impact, both medical and social, for the individual as well as for the family. Treatments developed for epilepsy have largely been empirical rather than derived from knowledge of basic mechanisms, because the mechanisms underlying seizure occurrence and epileptogenesis are poorly understood. The Epilepsy Phenome/Genome Project (EPGP) is a large-scale, national, multi-institutional, collaborative research project aimed at advancing our understanding of the genetic basis of the most common forms of idiopathic and cryptogenic epilepsies and a subset of symptomatic epilepsy; i.e. epilepsies that are probably related to genetic predispositions or developmental anomalies rather than endogenous, acquired factors such as CNS infection, head trauma or stroke. The overall strategy of EPGP is to collect detailed, high quality phenotypic information on 3,750 epilepsy patients and 3,000 controls, and to use state-of-the-art genomic ...
Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy Immunomodulatory interventions for focal epilepsy syndromes Interventions for psychotic symptoms concomitant with epilepsy. Intravenous immunoglobulins for epilepsy. Ketogenic diet and other dietary treatments for epilepsy. Lamotrigine add-on for drug-resistant partial epilepsy. Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures. Lamotrigine versus carbamazepine monotherapy for epilepsy. Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review. Losigamone add-on therapy for partial epilepsy. Melatonin as add-on treatment for epilepsy. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the ...
Childhood Epilepsy Research, Professor Deb Pals Neuro Lab at Kings College London is a partnership of clinical and basic science researchers, parents and charities dedicated to finding the causes of childhood epilepsy.
Disclaimer: Epilepsy Research UK is completely neutral and is not affiliated with any pharmaceutical company, or any particular drug compound.Marinus Pharmaceuticals announced yesterday that their drug candidate, ganaxolone, developed for adults with drug-resistant focal onset epilepsy, did not ...
The Comprehensive Epilepsy Center at Childrens Mercy offers innovative treatment and support for children with seizure disorders and their families. We are recognized by the National Association of Epilepsy Centers as a Level 4 Center, the highest level in epileptic care. As one of only a dozen pediatric epilepsy centers in the nation, we are able to provide you with the most complete diagnostic and treatment services available.. Our EEG lab, which performs tests to evaluate and record brain wave patterns to detect potential problems, is ABRET certified. This means our technologists and facilities meet the highest standards for providing excellent quality EEGs every time. Fewer than 10% of labs across the country achieve this certification.. Whether youre looking for a diagnosis, a second opinion, or the latest research-supported treatment options, the Childrens Mercy Comprehensive Epilepsy Center team is here to help.. ...
The efforts of the International League against Epilepsy to devise classifications of the epilepsies has greatly improved communication among epileptologists and influenced both basic and clinical research. The efforts of the International League against Epilepsy (ILAE) to devise classifications of the epilepsies has greatly improved communication among epileptologists and influenced both basic and clinical research. Several classifications have been proposed since 1970; the most recent classification of epilepsy syndromes and epilepsies was published in 1989. Since 1997, the ILAE Task Force on Classification and Terminology has been evaluating this classification and some modifications have been recommended. Although the 1989 classification can be criticized and needs to be updated, it has been widely accepted and is universally employed. Consequently, the Task Force has agreed not to propose a replacement until a clearly better classification can be created.
Background: Neurocysticercosis is a major cause of epilepsy in developing countries and is endemic in Brazil. To test the hypothesis that the aetiological profile of patients with intractable epilepsy in Brazil includes neurocysticercosis, we conducted a cross sectional study investigating the aetiology of intractable epilepsy.. Methods: A total of 512 patients evaluated at the outpatient clinic for intractable epilepsy at the Ribeirão Preto School of Medicine were included in the survey. Medical intractability was determined on the basis of seizure incidence and severity, and response to appropriate epilepsy management. Neuroimaging included brain CT with non-contrasted and contrasted phases and high resolution MRI. Patients were divided into neurocysticercosis and non-neurocysticercosis groups according to previous diagnostic criteria.. Results: The most common epileptogenic lesions were mesial temporal sclerosis (MTS; 56.0%), malformations of cortical development (12.1%), and brain tumours ...
The Canadian Epilepsy Alliance Launches A New Epilepsy Comic Book As Part of BuskerFest Festival Activities. The Canadian Epilepsy Alliance (CEA) is thrilled to announce the launch of a new comic series designed to educate children about the most common neurological disorder in Canada, epilepsy. The Medikidz Explain Epilepsy comic series tells a fictional story based on the experiences of 14-year-old Jack, who is navigating middle school while living with epilepsy.. Despite the fact that epilepsy affects 1 in 100 Canadians, there is still so much misinformation and lack of awareness out there, says Gail Dempsey, President of the Canadian Epilepsy Alliance. Addressing the information gaps about epilepsy is key and by educating children in a fun way that resonates, like with the comic series, we can close that gap.. READ MORE. ...
This is a study to see if vitamin E helps children with epilepsy have fewer seizures. About 20-30% of children with epilepsy do not have adequate seizure control with established antiepileptic drugs (AEDs). Other options for patients with uncontrolled epilepsy are newer antiepileptic medications, ketogenic diet and surgery. However, a small percentage of patients are candidates for these options. Therefore, additional treatments are needed to improve seizure control in patients with uncontrolled epilepsy. Animal studies have shown an association between vitamin E supplementation and seizure reduction. A study in children also showed that vitamin E helped reduce seizures. However, a similar study in adults did not show a reduction in seizures with vitamin E supplementation. Therefore, this research study is being done to help define vitamin Es usefulness and safety as a treatment for epilepsy. Fifty patients will be recruited from the Childrens Epilepsy Program at The Childrens Hospital in ...
The Epilepsy Family Study of Columbia University (EFSCU) is a long-term study of ways in which genes contribute to epilepsy risk. One of our main goals is to identify genes that play a role in epilepsy. Knowledge about the genes associated with epilepsy could potentially be very important for early identification and treatment of epilepsy in susceptible individuals. Genetic information can also help researchers and physicians understand what causes epilepsy and lead to the development of new methods for treatment or prevention of the different epilepsy syndromes. Thanks to the many families and individuals that volunteered for our studies over the past twenty years, weve made a number of important discoveries. While we continue to search for genes associated with epilepsy, weve also done important work on other aspects of epilepsy genetics. For example, recent studies have explored the relationship between epilepsy and other disorders, such as migraines and depression. Weve also begun to ...
1. Benbadis SR, Tatum WO, Gieron M. Idiopathic generalized epilepsy and choice of antiepileptic drugs. Neurology 2003; 61(12): 1793-5. 2. Panayiotopoulos CP. Idiopathic Generalised Epilepsies. In: Panayiotopoulos CP, editor. The Epilepsies: Seizures, Syndromes and Management. Chipping Norton: Bladon Medical Publishing 2005: 271-339. 3. Duron RM, Medina MT, Martinez-Juarez IE, Bailey JN, Perez-Gosiengfiao KT, Ramos-Ramirez R et al. Seizures of idiopathic generalized epilepsies. Idiopathic generalized epilepsies recognized by the International League Against Epilepsy. Use and abuse of EEG in the diagnosis of idiopathic generalized epilepsies. Epilepsia 2005; 46(Suppl 9): 34-47. 4. Nordli DR, Jr. Idiopathic generalized epilepsies recognized by the International League Against Epilepsy. Epilepsia 2005; 46(Suppl 9): 48-56. 5. Ferner RE, Panayiotopoulos CP. Phantom typical absences, absence status and experiential phenomena. Seizure 1993; 2(3): 253-256. 6. Panayiotopoulos CP. Syndromes of idiopathic ...
Orrin Devinsky is Professor of Neurology, Neurosurgery, and Psychiatry at the NYU School of Medicine, where he directs the Epilepsy Center. He also directs the Saint Barnabas Institute of Neurology. His epilepsy research includes cannabidiol, autism, genetic epilepsies, sudden death in epilepsy (SUDEP), healthful behavioral changes, therapeutic electrical stimulation, quality-of-life, cognitive and behavioral issues, and surgical therapy. He is the Principal Investigator for the North American SUDEP Registry and for the SUDC Registry and Research Collaborative. He is on the Executive Committee of the SUDEP Institute and Scientific Advisory Boards of the Epilepsy Foundation, Dup15q Alliance, Tuberous Sclerosis Association, KCNQ2 Cure Alliance Foundation, and Chairs the Loulou Foundation CDKL5 Program of Excellence. He serves as the lead investigator for the Epidiolex Dravet and Lennox-Gastaut studies and the PTC Ataluren study in genetic epilepsies. He founded Finding A Cure for Epilepsy and ...
TY - JOUR. T1 - Brain glucose metabolism and its relation to amyloid load in middle-aged adults with childhood-onset epilepsy. AU - Joutsa, Juho. AU - Rinne, Juha O.. AU - Karrasch, Mira. AU - Hermann, Bruce. AU - Johansson, Jarkko. AU - Anttinen, Anu. AU - Eskola, Olli. AU - Helin, Semi. AU - Shinnar, Shlomo. AU - Sillanpää, Matti. PY - 2017. Y1 - 2017. U2 - 10.1016/j.eplepsyres.2017.09.006. DO - 10.1016/j.eplepsyres.2017.09.006. M3 - Artikel. VL - 137. SP - 69. EP - 72. JO - Epilepsy Research. JF - Epilepsy Research. SN - 0920-1211. ER - ...
Antiepileptic drugs (AEDs) were frequently used as polytherapy until evidence from a series of studies in the late 1970s and early 1980s suggested that patients derive as much benefit from monotherapy as polytherapy.1-3 AED polytherapy is increasingly becoming popular again and as much as 30-40% of prescriptions to children are polytherapy.4 ,5 The availability of new-generation AEDs in the last two decades has encouraged polytherapy. AEDs such as lamotrigine, topiramate, levetiracetam, oxcarbazepine and zonisamide have been approved for paediatric use and are recommended mostly as adjuncts or as second-line agents.6 Despite the availability of more AEDs, the prevalence of poorly controlled epilepsies still remains the same. About 30% of epilepsies are resistant to treatment.7 Drug-resistant epilepsies almost always require polytherapy, but the question of the best treatment approach when an initial monotherapy fails is still debatable. ...
Group Name: Epilepsy Toronto - Adults with Epilepsy Connection (AWE). Description: Epilepsy Toronto is a non-profit agency that has supported people living with epilepsy for over 50 years. They offer free PROGRAMS AND SERVICES, host exciting EVENTS throughout the year, and provide lots of epilepsy information as well. Whether you have epilepsy, know someone who lives with seizures, or are just an interested community member wanting to learn more, Epilepsy Toronto can help! If you are otherwise engaged during the day and is unable to take advantage of day-time activities at Epilepsy Toronto, then AWE Connection may be just what you need. Come be a part of a support group that provides you with the opportunity to connect with other adults living with epilepsy, learn more about epilepsy and share your feelings and concerns in a warm and supportive environment.. Where: 468 Queen St. East, Suite 210 , Toronto, ON M5A 1T7. When: Third Tuesday of every month, from 6 p.m. until 8 p.m.. Contact: Rosie ...
Register. Looking for a fun way to run and raise money to help find a cure for epilepsy? Join CURE Epilepsys virtual Run for Research from April 26 to May 2. Run 26.2 miles over the course of a one-week period for the 1 in 26 Americans living with epilepsy. Until we can run together in the fall, CURE Epilepsy Champions of all fitness levels will run independently to raise funds to find a cure.. Looking to run a marathon this October? CURE Epilepsy has secured 5 charity spots in the Bank of America Chicago Marathon being run on Sunday, October 10. Find out more about how you can join Team CURE Epilepsy.. Looking for a way to help spread awareness of the importance of epilepsy research and help fundraise at the same time? Become a CURE Epilepsy Champion. Learn more!. ...
EpiReg is a research- and quality registry and biobank for patients treated at Department of Neurology, Haukeland University Hospital. The aim of EpiReg is to use the collected information to increase quality and excellence in epilepsy treatment. We also use the information for research EpiReg is initated and maintained by Bergen Epilepsy Research Group (BERG). EpiReg was established in 2019 with funding from Helse Vest, later also from Helse Bergen. The regional ethical committee has approved it (REK 2018/586). The database is integrated with the hospital record system of the hospital so that all registered information is also visible in the patients individual hospital record. EpiReg was established in cooperation with Norsk Epilepsiforbund, the national patient organization, and it has continuous user support. EpiReg interacts with the national EpilepsiNett project supported by the Research Council of Norway. EpiReg collects both patient-reported data and medical information. The aim is to ...
We believe that no one with epilepsy should go it alone.. We Are Creating an Epilepsy Smart Australia. Research shows that, despite the conditions prevalence, ninety percent of Australians dont have access to the epilepsy support they need. In response, the Australian Government has funded the Epilepsy Foundation to take our work to a national scale through a new program titled Epilepsy Smart Australia. We are expanding our delivery of services that will reduce the chronic health impacts experienced by Australians of all ages living with epilepsy.. We Support People Living with Epilepsy. No one with epilepsy should go it alone. Every case of epilepsy is unique and everyone with epilepsy will need some form of support in their life. The Epilepsy Foundation works to ensure that:. ...
Overall mortality, incidence of sudden unexpected death, and cause of death were determined in 601 adult outpatients with epilepsy at a tertiary referral centre. The patients were followed up from 1990 to 30 June 1993. There were 24 deaths among the 601 patients (1849 patient years) with a standardised mortality ratio of 5.1 (95% confidence interval 3.3-7.6) of which 14 were related to epilepsy. Underlying disease of which epilepsy was a symptom accounted for four deaths only. An incidence of sudden deaths (including seizure related) was of the order of 1:200/year. In conclusion, excess mortality in chronic epilepsy is more likely to be related to the epilepsy itself than to underlying pathology. The relatively high incidence of sudden deaths found in this hospital based cohort has important implications for patient management.. ...
TY - BOOK. T1 - Models of Seizures and Epilepsy. T2 - Second Edition. AU - Pitkänen, Asla. AU - Buckmaster, Paul S.. AU - Galanopoulou, Aristea S.. AU - Moshé, Solomon L.. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure. Offers insights on the use of novel technologies that can be applied in experimental ...
Scientists at Seattle Childrens Research Institute have found a way to rapidly suppress epilepsy in mouse models by manipulating a known genetic pathway using a cancer drug currently in human clinical trials for the treatment of brain and breast cancer.. The findings, reported in the journal eLIFE, open a new class of drugs to study for the treatment of intractable epilepsy, a severe form of epilepsy that does not respond to drugs. About 460,000 children have epilepsy in the United States, and about 20 percent of them have intractable epilepsy.. Intractable epilepsy is devastating because theres no way to control seizures in those patients, and some of them will undergo surgery to remove the brain tissue that causes the epilepsy, said Dr. Kathleen Millen, a researcher at the institutes Center for Integrative Brain Research and lead study author. We were able to stop seizures in mouse models within one hour of treatment using a drug that targets a genetic pathway linked to intractable ...
As a part of National Epilepsy Awareness Month, the Epilepsy Foundation (EF) launched the #AimForZero seizures campaign. A goal of this campaign is to reduce the risk of sudden unexpected death in epilepsy (SUDEP) through patient education. Talking about early death in epilepsy, particularly SUDEP, is hard, but it is important to let people know their risks.. Talking about SUDEP is a critical part of epilepsy care. Everyone should know what it is, and what it is now. Only by talking about it can people learn their risks and take action to improve seizure control, and ideally lessen their risks of SUDEP.. Invite your patients and their families to join the Epilepsy Foundation on Tuesday, November 14, 2017, 8 to 9 p.m. ET for a webinar on Talking About SUDEP. Dr. Daniel Friedman, epilepsy.coms SUDEP Editor, and Wendy Miller PhD, RN, CCRN of Indiana University, will discuss the latest thinking on SUDEP and the importance of talking about it and knowing your risks. Hear perspectives and tips from ...
There are approximately 250,000 people living with epilepsy in Australia and 65 million worldwide. Epilepsy and the unpredictably of the recurrent seizures can impact the independence and confidence of people living with the disease.. While many people effectively manage the condition with their first or second anti-epileptic drugs, if it fails to be treated the chance of responding to further drugs is significantly diminished, leaving about 30 percent of patients with drug resistant epilepsy.. This means many people are faced with few choices which allow them to effectively manage their debilitating condition. There are also legal restrictions that can impact their job prospects and independence, for example understandably preventing many with epilepsy from even holding a drivers license.. This grant will help the University to accelerate its work on a seizure advisory system for adult individuals diagnosed with epilepsy who want or used to drive a vehicle.. The system, NeuroSyd, aims at ...
BACKGROUND: There is little data on the burden or causes of epilepsy in developing countries, particularly in children living in sub-Saharan Africa. METHODS: We conducted two surveys to estimate the prevalence, incidence and risk factors of epilepsy in children in a rural district of Kenya. All children born between 1991 and 1995 were screened with a questionnaire in 2001 and 2003, and those with a positive response were then assessed for epilepsy by a clinician. Active epilepsy was defined as two or more unprovoked seizures with one in the last year. RESULTS: In the first survey 10,218 children were identified from a census, of whom 110 had epilepsy. The adjusted prevalence estimates of lifetime and active epilepsy were 41/1000 (95% CI: 31-51) and 11/1000 (95% CI: 5-15), respectively. Overall two-thirds of children had either generalized tonic-clonic and/or secondary generalized seizures. A positive history of febrile seizures (OR=3.01; 95% CI: 1.50-6.01) and family history of epilepsy (OR=2.55; 95% CI
Brigham and Womens Hospital is fortunate to have Page B. Pennell, MD, a noted researcher and leading authority on epilepsy and pregnancy. Dr. Pennell is the director of research for the Division of Epilepsy in the Department of Neurology. She oversees multi-center research collaborations on a wide breadth of epilepsy-related topics, from womens issues such as hormones, pregnancy and menopause to new epilepsy treatments and neuroimaging in surgical planning and treatment of epilepsy.. Before joining the BWH staff, she was an associate professor of Neurology and director of the Epilepsy Program at Emory University School of Medicine in Atlanta, Georgia.. Dr. Pennell has served on the editorial boards for the journals Epilepsia and The Neurologist. Dr. Pennell has also published over 50 papers in her field. She is a fellow in the American Neurological Association and a member of the American Epilepsy Society and American Academy of Neurology. In the American Epilepsy Society, she has served as ...
Profiling the Evolution of Depression After Epilepsy Surgery. the epilepsy cant be excluded as demanded by DSM-IV certainly. Exhaustion and psychomotor slowing are generally due to antiepileptic medicines (AEDs). Melancholy in epilepsy could be intermittent and of shorter length or merely linked to seizures in the preictal or postictal stage (6). Is it feasible that melancholy in epilepsy can be a different disease procedure altogether than main melancholy without epilepsy? Wrench and co-workers certainly attemptedto element in psychosocial elements that additional cloud the issue. In addition the influence of antiepileptic medications on depressive disorder cannot be ignored. AED differences on depressive disorder were not systematically examined in this study most likely due the variety of AEDs and the fact that all patients were taking AEDs. What is the true pathophysiologic Rabbit Polyclonal to MPHOSPH9. substrate of depressive disorder in epileptic patients? Is it the seizures the ...
Behavioral and related disorders are frequently reported in association with childhood epilepsy but the reasons for this are unclear. In a long-term prospective, community-based study of newly-diagnosed childhood epilepsy, behavioral assessments (Child Behavior Checklist) were performed in children 8 to 9 years after the initial diagnosis of epilepsy to determine the impact of remission and medication status on behavioral problems. Children with epilepsy were also compared with sibling controls. A total of 226 children (108 females, 118 males; mean age 13y 1mo [SD 2y 8mo], range 8-17y) with idiopathic or cryptogenic epilepsy were included in the analyses. One hundred and twenty-eight matched pairs were included in analyses of case-sibling differences. Lack of remission and current medication use were associated with worse behavioral problem and competency scores. Lack of remission generally had a greater effect than medication use, except for attention problems; medication status had the more
This survey identified key areas of improvement in terms of knowledge and development of specific skills for epileptologists regarding management of the psychiatric comorbidities of epilepsy. For the first time, psychiatrists were involved in the process and it was possible to identify specific needs for adult and child neurologists treating patients with epilepsy.. Epileptologists are keen to improve their clinical skills and screening during routine clinical practice seems to be the priority. Most adult neurologists feel inadequate or not skilled enough when dealing with patients with epilepsy and ASD, ADHD, or IDs in general. Child neurologists are historically better trained in these conditions and thus, usually more adept in their management. A prospective community-based study of children and adolescents with active epilepsy showed that up to 40% of patients have IDs, one third have ADHD, and around 20% have ASD (Reilly et al., 2014). In addition, a community-based survey of more than ...
Seizures eliminated in 48 percent of patients and QOL improved in 80 percent of patients according to 26-year follow-up. While epilepsy surgery is a safe and effective intervention for seizure control, medical therapy remains the more prominent treatment option for those with epilepsy. However, a new 26-year study reveals that following epilepsy surgery, nearly half of participants were free of disabling seizures and 80% reported better quality of life than before surgery. Findings from this study-the largest long-term study to date-are now available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE).. More than 50 million individuals worldwide suffer from seizures caused by epilepsy according to a 2001 report by the World Health Organization (WHO). Medical evidence shows that compared with the general population, epilepsy patients have significantly poorer health-related quality of life, higher rates of co-morbidites, and lower ...
The European Forum on Epilepsy Research (ERF 2013) took place in Dublin from the 26th - 29th May 2013. Find out more at the IBE blog.
Background:. - Medically intractable epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respond to medication will respond to surgical treatment, relieving seizures completely or almost completely in one-half to two-thirds of patients who qualify for surgery. The tests and surgery performed as part of this treatment are not experimental, but researchers are interested in training more neurologists and neurosurgeons in epilepsy surgery and care in order to better understand epilepsy and its treatment.. Objectives:. - To use surgery as a treatment for medically intractable epilepsy in children and adults.. Eligibility:. - Children and adults at least 8 years of age who have simple or complex partial seizures (seizures that come from one area of the brain) that have not responded to medication, and who are willing to have brain surgery to treat their medically intractable epilepsy.. Design:. ...
Over the time there has been great advancement in the field of epilepsy in terms of diagnosis and management of patients with epilepsy. But overall there is not much change in the classification of epilepsy and epileptic syndromes. The role of genetics is also increasing for definitive diagnosis of epilepsy, especially genetic epilepsy syndromes. Imaging has also improved immensely to delineate the lesion in a better way so that more and more patients can be operated to resect the seizure focus for control of epilepsy. Newly selective surgical techniques are being developed with minimal possible damage to the anatomy of the brain. Now epilepsy neurosurgeons care more to prevent postoperative gliosis which can later develop into seizure focus. The role of EMU is expanding for definitive diagnosis and management of epileptic patients. It has become an inevitable diagnostic tool for epileptic patients referred to a tertiary care centre for diagnosis and control of seizures and other paroxysmal ...
Siddhartha Nadkarni, MD, Director. Duration: 1-2 years. For candidates who have completed an ACGME-accredited neurology residency and an ACGME approved Clinical Neurophysiology or Epilepsy Fellowship. This is an Non-ACGME-accredited fellowship program. The educational purpose of the program is to primarily give fellows already trained in clinical neurophysiology or clinical epilepsy the opportunity to apply their knowledge to epilepsy research and obtain further training in scalp/ intracranial EEG, electrocorticography, cortical mapping, as well as clinical management of patients with epilepsy.. Contact:. Siddhartha Nadkarni, ...
The present study shows an association between shorter duration of epilepsy and better seizure outcome after resective epilepsy surgery in a systematic review and meta-analysis. The discussion about the importance of earlier epilepsy surgery has been around for a long time and motivated US researchers to initiate an ambitious RCT, ERSET, to determine whether surgery in patients with drug-resistant temporal lobe epilepsy soon after failure of 2 antiepileptic drug trials is superior to continued medical management.2 A sample size of 200 participants was originally planned, but the trial had to be terminated prematurely. Only 38 patients were recruited with a mean epilepsy duration of 10.9 years,2 which though it may seem rather long is much shorter than the mean epilepsy duration of 19.7 years in the first randomized controlled trial.1 Nevertheless, even in this limited cohort, resective surgery and antiepileptic drug treatment resulted in a lower probability of seizures during the second year of ...
Lacosamide vs Controlled-Release Carbamazepine Monotherapy as Initial Epilepsy Treatment. Information sourced from NEJM Journal Watch:. Lacosamide vs. Controlled-Release Carbamazepine Monotherapy as Initial Epilepsy Treatment. Lacosamide was no less effective for new-onset seizures in patients with clinically suspected partial epilepsy.. Nearly all new antiepilepsy medications (AEDs) obtain initial indications as adjunctive (add-on) therapy in patients with medically uncontrolled epilepsy, yet most patients are treated (or wish to be) with only one medicine. Very few head-to-head comparisons have been done between new AEDs and older medications with established efficacy in the largest generalizable populations: those with new-onset seizures or those that can be controlled with one AED. Lacosamide (LCM) is FDA-approved as monotherapy based on historical controls and is not approved as monotherapy in Europe. This large international, double-blind, randomized, manufacturer-sponsored study compared ...
TORONTO, ON (March 6, 2012) - Today at Queens Park, 40 members of Ontarios epilepsy community, led by Epilepsy Ontario and the Epilepsy Cure Initiative, gathered to meet with MPPs and policy advisors to increase awareness of epilepsy within government and advocate for the implementation of an Ontario Epilepsy Strategy. The key topics of discussion included the impact of epilepsy on Ontarians, consistent standards of patient care, improved access to treatment and disability and employment supports.. Recently, the Ontario Health Technology Advisory Committee released recommendations to improve access to and standardize epilepsy care in Ontario which we strongly support as the foundation for a provincial epilepsy strategy, said Rozalyn Werner-Arcé, Executive Director, Epilepsy Ontario. On behalf of Ontarians living with epilepsy, their families and employers, we ask the government to ensure it incorporates the key role of community epilepsy organizations in the implementation of this ...
TY - JOUR. T1 - Status epilepticus in a population-based cohort with childhood-onset epilepsy in Finland. AU - Sillanpää, Matti. AU - Shinnar, Shlomo. PY - 2002/9/1. Y1 - 2002/9/1. N2 - Little is known about the time course over which status epilepticus occurs in childhood-onset epilepsy and its impact on long-term prognosis. A population-based cohort of 150 children younger than age 16 years with new onset epilepsy between 1961 and 1964 residing in the catchment area of Turku University Hospital was observed prospectively until 1997. The occurrence of status epilepticus and recurrent status epilepticus, risk factors for status epilepticus, and the impact of status epilepticus on prognosis were examined. Of the 150 cases, 41 patients (27%) experienced an episode of status epilepticus of whom 22 patients (56%) had two or more episodes. The risk of status epilepticus was highest at the onset of the disorder with 30 (73%) cases occurring before (n = 12) or at (n = 18) onset and 37 (90%) cases ...
Epilepsy, also known as seizure disorder, is a common disease of the brain affecting about one percent of the population. It can affect any person at any age. More than 36,000 Mississippians live with epilepsy. Recognized as the states only level 4 epilepsy center accredited by the National Association of Epilepsy Centers, University of Mississippi Medical Center provides comprehensive testing and treatment for patients of all ages.University Comprehensive Epilepsy Center is dedicated to the care of people with epilepsy. The center offers state-of-the-art medical and surgical treatment of seizures/epilepsy in adults and children. Our goal is to help patients gain control of seizures and optimize their quality of life.Diagnosis, Treatment, and ReferralsA full complement of advanced diagnostic tests is available for seizures diagnosis, classification, and evaluation for surgical treatment of epilepsy. The centers inpatient epilepsy monitoring unit combines video and EEG monitoring of patients to
According to a recent study, children with Rolandic epilepsy should receive treatment in order to reduce their risk of cognitive and behavioural problems.BackgroundRolandic epilepsy is the most common form of childhood focal epilepsy syndrome, accounting for 15-20% of epilepsies in people aged b ...
Background: Treatment of pediatric epilepsy has advanced with the development of new antiepileptic drugs. The European Medicines Agency recommends that more research into pediatric drugs for epilepsy is needed.. Objectives: To characterize utilization of antiepileptic drugs in children with a specific emphasis on newer antiepileptic drugs.. Methods: Data were obtained from the German Pharmacoepidemiological Research Database for the period 2004-2006, including prescription data of more than 14 million insurance members from all over Germany. Descriptive analyses were perfomed to assess prevalence and incidence of antiepileptic drug use stratified by age and sex. Mono- and combination therapy were considered as well as the clinical speciality of the prescribing physician.. Results: We identified 13,197 children who received a total of 226,856 antiepileptic drug dispensations. Of these, 140,992 (62.15%) were conventional and 85,864 (37.85%) were newer antiepileptic drugs. Most commonly prescribed ...
How To Really Make Your Penis Bigger] , Natural Aphrodisiacs Epilepsy Drugs And Erectile Dysfunction. Just like those second generations who like to Cost Of Viagra With Insurance run to Hong Kong Top Rated Breast Enhancement Pills Island a few years ago, there Epilepsy Drugs And Erectile Dysfunction Natural Alternatives To Viagra are not a few elders I Have A Pimple On My Pennis at the level of generals, provinces, and Epilepsy Drugs And Erectile Dysfunction Most Safe ministries in the family, Epilepsy Drugs And Erectile Dysfunction Most Safe and they are simply Epilepsy Drugs And Erectile Dysfunction embarrassed to Epilepsy Drugs And Erectile Dysfunction talk Epilepsy Drugs And Erectile Dysfunction But now it seems that Epilepsy Drugs And Erectile Dysfunction no matter whether Qin Lin s background is big or small, Ning Qiangwei can be sure that this teenager who seems to Diabetes And Impotence be only about eighteen years old Epilepsy Drugs And Erectile Dysfunction Epilepsy Drugs And Erectile ...
Aim. To study the efficacy of vagus nerve stimulation (VNS) therapy in a highly drug-resistant childhood epilepsy patient group and to investigate the effect of age at implantation on efficacy. Methods. The efficacy of VNS treatment was analysed in a cohort of 70 patients with drug-resistant epilepsy. Both children with focal (n=16) and generalized epilepsies (n=54) were included. Age at implantation varied between 19 months and 25 years. Results. Overall, responder rate was 54% with 5.7% children becoming seizure-free. The only factor in our analysis that could predict good outcome was age at implantation. In the youngest group ...
Get information on the types of pediatric epilepsy surgery and the symptoms, treatment, and causes of childhood epilepsy. Learn about epilepsy surgery recovery, side effects, and the procedure for epilepsy surgery. Discover the three main surgical types, including resective.
In this cohort of 519 patients, 60 (11.6%) had epileptic seizures associated with SLE disease activity. The frequency of epileptic seizures in previous studies ranged between 8.3 and 28%.1,5-10,21⇓⇓⇓⇓⇓⇓⇓ Epileptic seizures at disease onset were identified in 19 (31.7%) of these 60 patients. Epileptic seizures occurred after the onset of the disease in 41 (68.3%) patients. Fifty-three (88.3%) patients had a single epileptic seizure episode, and 7 (11.7%) had recurrent epileptic seizures. Generalized tonic-clonic and complex partial seizures were the most common epileptic seizures observed in this study. At disease onset, epileptic seizures were associated with stroke and the presence of moderate to higher titers of IgG antiphospholipid antibodies. The association between higher titers of antiphospholipid antibodies and seizures has been demonstrated previously.2,4,9,22-26⇓⇓⇓⇓⇓⇓⇓. Epileptic seizures may occur in isolation or accompany other neurologic ...
We provide info on our second election ask, which is to ensure there is at least one adult and one paediatric Epilepsy Specialist Nurse (ESN) in each health board.
article{6985217, abstract = {This study, supported by the Rwandan Ministry of Health and the World Health Organization, was conducted in 2005 to determine the prevalence of epilepsy and its sociocultural perception in Rwanda, as well as epilepsy-related knowledge and practices of health-care professionals (HCPs). A cross-sectional, nationally representative survey was conducted throughout Rwanda by trained investigators. Participants were recruited by random cluster sampling based on the organization of administrative units in the country. Overall, 1137 individuals (62% from rural areas) were interviewed. The prevalence of epilepsy was estimated to be 49 per 1000 people or 41 per 1000 for active epilepsy. Onset of epilepsy before the age of 2 years was reported in 32% of the cases. Family history of epilepsy, head trauma, and premature delivery were reported in 53%, 50%, and 68% of the cases, respectively. Most (68%) patients did not receive any medical treatment for epilepsy; 21.5% had received ...
1. Baxendale S. The representation of epilepsy in popular music. Epilepsy Behav. 2008; 12(1):165-169. 2. Tuft M, Nakken KO. Epilepsy and stigma in popular music. Tidsskr Nor Laegeforen. 2014;134:2290-3. 3. Kuscu DY, Kayrak N, Karasu A, Gul G, Kirbas D. Ictal singing due to left mesial temporal sclerosis. Epileptic Disord. 2008;10(2):173-6. 4. Barker AS, Bowen JR, Sharrack B, Sarrigiannis PG. Tap dancing in epilepsy. Epilepsy Behav. 2011;20(1):150-1. 5. Bagla R, Khoury JS, Skidmore C. Teaching Video NeuroImages: dancing epilepsy. Neurology. 2009; 72(22):e114. 6. Janz D. Epilepsy, viewed metaphysically: an interpretation of the biblical story of the epileptic boy and of Raphaels transfiguration. Epilepsia. 1986;27(4):316-22. 7. Mann MW. The epileptic seizure and the mystery of death in Christian painting. Epilepsy Behav. 2010; 17(2):139-46. ...
Purpose: The restricted genetic diversity and homogeneous molecular basis of Mendelian disorders in isolated founder populations have rarely been explored in epilepsy research. Our long-term goal is to explore the genetic basis of epilepsies in one such population, the Gypsies. The aim of this report is the clinical and genetic characterization of a Gypsy family with a partial epilepsy syndrome. Methods: Clinical information was collected using semistructured interviews with affected subjects and informants. At least one interictal electroencephalography (EEG) recording was performed for each patient and previous data obtained from records. Neuroimaging included structural magnetic resonance imaging (MRI). Linkage and haplotype analysis was performed using the Illumina IVb Linkage Panel, supplemented with highly informative microsatellites in linked regions and Affymetrix SNP 5.0 array data. Results: We observed an early-onset partial epilepsy syndrome with seizure semiology strongly suggestive ...
New research reveals a shared genetic susceptibility to epilepsy and migraine. Findings published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), indicate that having a strong family history of seizure disorders increases the chance of having migraine with aura (MA).. Medical evidence has established that migraine and epilepsy often co-occur in patients; this co-occurrence is called comorbidity. Previous studies have found that people with epilepsy are substantially more likely than the general population to have migraine headache. However, it is not clear whether that comorbidity results from a shared genetic cause.. Epilepsy and migraine are each individually influenced by genetic factors, explains lead author Dr. Melodie Winawer from Columbia University Medical Center in New York. Our study is the first to confirm a shared genetic susceptibility to epilepsy and migraine in a large population of patients with common forms of epilepsy.. For the present study, ...
The temporal lobe would be the part in red. Only the left temporal lobe is shown.. The temporal lobe is separated into 2 parts: right and left. Its responsible for auditory processing, processing of semantic & lexical information in speech, and long-term memory. On the other hand, epilepsy aka seizure disorder is a common neurological disorder that causes recurrent & unprovoked seizures in patients. These seizures happen when clusters of neurons fire excessively/abnormally/synchronously. Combine these two, and youve got temporal lobe epilepsy.. Temporal lobe epilepsy causes simple and complex partial seizures. Simple partial seizures simply cause unusual behaviours and patterns of cognition, including hallucinations and paranormal experiences; complex partial seizures can render the patient disabled and lose awareness temporarily. If one is unlucky though, it may spread and become a tonic-clonic seizure, a type of seizure that affects the entire brain, and is much more lethal.. ...
The temporal lobe would be the part in red. Only the left temporal lobe is shown.. The temporal lobe is separated into 2 parts: right and left. Its responsible for auditory processing, processing of semantic & lexical information in speech, and long-term memory. On the other hand, epilepsy aka seizure disorder is a common neurological disorder that causes recurrent & unprovoked seizures in patients. These seizures happen when clusters of neurons fire excessively/abnormally/synchronously. Combine these two, and youve got temporal lobe epilepsy.. Temporal lobe epilepsy causes simple and complex partial seizures. Simple partial seizures simply cause unusual behaviours and patterns of cognition, including hallucinations and paranormal experiences; complex partial seizures can render the patient disabled and lose awareness temporarily. If one is unlucky though, it may spread and become a tonic-clonic seizure, a type of seizure that affects the entire brain, and is much more lethal.. ...
PURPOSE OF REVIEW: This review summarizes recent evidence on the seizure, safety, cognitive and psychosocial outcomes of epilepsy surgery and their predictors. RECENT FINDINGS: Risks of serious surgical complications have dramatically decreased over years to drop below 1% for temporal lobe resections. Although chances of postoperative seizure freedom largely vary between recent series, some data suggest that long-term seizure control might be achieved in over 80% of patients with mesial temporal lobe epilepsy or neocortical epilepsy associated with type 2 focal cortical dysplasia, and in up to two-thirds of patients with extratemporal lobe epilepsy. In the same conditions, some recent series challenge the classic view that a normal MRI is associated with worse outcome, an important finding given the greater proportion of MRI-negative patients now considered for epilepsy surgery. SUMMARY: These provocative findings appear to partly reflect the advances in the optimal use or postprocessi
Early-onset absence epilepsy refers to patients with absence seizures beginning before age four and comprises a heterogeneous group of epilepsies. Onset of absence seizures in the first year of life is very rare. We report a girl with intractable absence seizures with onset at age eight months. Her seizures were characterised by loss of responsiveness, with eyes drifting upwards and some myoclonic jerks of the upper and lower limbs. These symptoms were accompanied by bilaterally symmetric high-amplitude 2-2.5 Hz generalised spike-and-wave discharges on the electroencephalogram. Her seizures were refractory to conventional antiepileptic drugs; treatment with adrenocorticotropic hormone was transiently effective. Comprehensive metabolic screening, cytogenetic, and genetic analysis did not determine an underlying cause of her condition. Patients with intractable, very early-onset absence epilepsy with a myoclonic component have an unfavourable outcome and may be classified under a new epileptic ...
To evaluate the efficacy of steroid therapy in epileptic encephalopathies and refractory epilepsies other than West syndrome. Retrospective analysis of treatment and outcome data of patients treated with steroids for epileptic encephalopathies. Outco
AIM: The aim of this study was to define the prevalence of and risk factors for behavioural disorders in children with epilepsy from a rural district of Tanzania by conducting a community-based case-control study. METHOD: One hundred and twelve children aged 6 to 14 years (55 males, 57 females; median age 12 y) with active epilepsy (at least two unprovoked seizures in the last 5 y) were identified in a cross-sectional survey and included in this study. Children who were younger than 6 years were excluded in order to eliminate febrile seizures. Behaviour was assessed using the Rutter scale; children who scored 13 or more were considered to have disordered behaviour. A comparison group was made up of age- and sex-matched children without epilepsy (n = 113; 57 males, 56 females; median age 12 y). RESULTS: Behavioural disorders were diagnosed in 68 of 103 (66%) children with epilepsy and in 19 of 99 (19%) controls. Disordered behaviour was significantly more common in children with epilepsy than in the
The unprovoked epileptic seizure is considered to be one with no cause, which excludes seizures connected with acute infections, traumas, central nervous system haemorrhages or metabolic disorders (disorders of the homeostasis-acidosis, hypoglicaemia, electrolyte dysbalance). The decision whether to treat the first unprovoked epileptic seizure, the risk of repeated seizure or development into epilepsy in children and young adolescents may be found in the instructions based on evidence. Analysis of the evidence based data points out that a number of children will have another seizure in a certain time period or will develop epilepsy regardless of antiepileptic drug therapy; therefore, a decision to start therapy has to be made on an individual basis. The retrospective study was conducted at the Neuropaediatric Department of the University Hospital Sisters of Mercy, which showed that 29 out of 226 children staying on the ward developed a second unprovoked epileptic seizure. Broad diagnostic ...
TY - GEN. T1 - Dynamic seizure imaging in patients with extratemporal lobe epilepsy. AU - Lu, Yunfeng. AU - Yang, Lin. AU - Worrell, Gregory A.. AU - Brinkmann, Benjamin. AU - Nelson, Cindy. AU - He, Bin. PY - 2012/12/14. Y1 - 2012/12/14. N2 - Epilepsy is a common neurological disease that affects about 50 million people worldwide. Extratemporal lobe epilepsy, which represents an important type of epilepsy, may involve seizure activity in various lobes and the surgical treatment in these patients tends to have less favorable surgical outcome. Noninvasive seizure imaging in drug-resistant patients is of vital importance to image the seizure onset zones (SOZs) and understand the mechanisms for an improved treatment plan. In this study, we directly imaged the seizure sources in 8 extratemporal lobe partial epilepsy patients from noninvasive EEG. The surgically resected regions and SOZs identified from intracranial EEG (iEEG) recordings were used to evaluate the source imaging results. All of the ...
TY - JOUR. T1 - Epilepsy surgery of low grade epilepsy associated neuroepithelial tumors: A retrospective nationwide Italian study. AU - Giulioni, M.. AU - Marucci, G.. AU - Pelliccia, V.. AU - Gozzo, F.. AU - Barba, C.. AU - Didato, G.. AU - Villani, F.. AU - Di Gennaro, G.. AU - Quarato, P.P.. AU - Esposito, V.. AU - Consales, A.. AU - Martinoni, M.. AU - Vornetti, G.. AU - Zenesini, C.. AU - Efisio Marras, C.. AU - Specchio, N.. AU - De Palma, L.. AU - Rocchi, R.. AU - Giordano, F.. AU - Tringali, G.. AU - Nozza, P.. AU - Colicchio, G.. AU - Rubboli, G.. AU - Lo Russo, G.. AU - Guerrini, R.. AU - Tinuper, P.. AU - Cardinale, F.. AU - Cossu, M.. AU - Epilepsy, the Commission for Epilepsy Surgery of the Italian League Against. N1 - Export Date: 23 February 2018 Extracted concepts Epilepsy PY - 2017. Y1 - 2017. U2 - 10.1111/epi.13866. DO - 10.1111/epi.13866. M3 - Article. VL - 58. SP - 1832. EP - 1841. JO - Epilepsia. JF - Epilepsia. SN - 0013-9580. IS - 11. ER - ...
Epilepsy Southwestern Ontario would like to thank all thank all guests, sponsors, donors and volunteers who participated in our Game Show Gala!. We are sincerely overwhelmed with the continued success of the gala, all of which would not be possible without our sponsor and donors.. We are happy to announce that this years Gala surpassed our goal, raising over $30,000!! Proceeds from the event will help us to further our mission by providing education and support services.. Our Game Show Gala was hosted at Brookside Banquet Centre on April 7, 2018.. Epilepsy Southwestern Ontario has been presenting a H.O.P.E. award (Helping Out People with Epilepsy) since 2005. Each year, it is awarded to an individual, group of individuals or organization who has demonstrated compassion and caring for people living with epilepsy. This is Epilepsy Southwestern Ontarios highest honour and we are pleased that the Ontario Brain Institute & EpLink (the Epilepsy Research Program of OBI) have been chosen to receive ...
TY - JOUR. T1 - Modeling of intracerebral interictal epileptic discharges. T2 - Evidence for network interactions. AU - Meesters, Stephan. AU - Ossenblok, Pauly. AU - Colon, Albert. AU - Wagner, Louis. AU - Schijns, Olaf. AU - Boon, Paul. AU - Florack, Luc. AU - Fuster, Andrea. PY - 2018/6/1. Y1 - 2018/6/1. KW - Stereo-electroencephalography. KW - Analysis framework. KW - Interictal epileptic discharges. KW - Spatiotemporal network interaction. KW - Epilepsy surgery. KW - TEMPORAL-LOBE EPILEPSY. KW - INDEPENDENT COMPONENT ANALYSIS. KW - EPILEPTOGENIC NETWORKS. KW - SOURCE LOCALIZATION. KW - BLIND SEPARATION. KW - CLUSTER-ANALYSIS. KW - BRAIN NETWORKS. KW - EEG. KW - SIGNALS. KW - SEEG. U2 - 10.1016/j.clinph.2018.03.021. DO - 10.1016/j.clinph.2018.03.021. M3 - Article. VL - 129. SP - 1276. EP - 1290. JO - Clinical Neurophysiology. JF - Clinical Neurophysiology. SN - 1388-2457. IS - 6. ER - ...
Learn how Focal Cortical Dysplasia is diagnosed and the seizure types that may be seen with it. GARD Answers GARD Answers Listen. CAUTION patients with focal cortical dysplasia, who have earlier age of seizure onset, may have a change in their seizure types over time, with the emergence of epileptic spasms or generalized seizure types, such as atypical absences, atonic and tonic seizures. Epub 2020 Jan 20. COVID-19 is an emerging, rapidly evolving situation. Malformations of cortical development and epilepsies: neuropathological findings with emphasis on focal cortical dysplasia. Please enable it to take advantage of the complete set of features! As FCD type II cannot be diagnosed with certainty in the clinic, in vivo identification by use of MRI is important. Focal cortical dysplasia (FCD) is a congenital abnormality of brain development where the neurons in an area of the brain failed to migrate in the proper formation in utero. Epileptic Disord. It is characterized by epileptic seizures that ...
We have developed a number or resources to help gain more knowledge about epilepsy and ways to improve seizure control and quality of life. Many of these resources are for a broad audience while others are targeted toward a more specific audience.. E-quip, An Epilepsy Resource for Youth: Specifically designed for youth, this resource covers topics concerning youth and has a number of videos with young people discussing their experiences.. rEaction: This resource is also aimed at youth with a focus on increasing epilepsy awareness for friends and peers of people with epilepsy.. Strong Foundations: This resource is designed to help parents with a child attending mainstream school to identify if their child is experiencing epilepsy-related learning challenges. It aims to give parents ideas about how to support their child to achieve their potential.. There are two free short online courses for school aged children to learn about epilepsy. Epilepsy Awareness. ...
Conjoint A/Prof Annie Bye has an extensive portfolio of research into paediatric epilepsy and neurology, with over 70 original research articles together with 70 abstracts published in international and national peer reviewed journals. Research topics include neonatal seizures, neuropsychological and language profiles in paediatric epilepsy, MRI correlates of childhood epilepsy syndromes, quality of life in paediatric epilepsy, and education of epilepsy to patients and medical staff. This research has been supported by NHMRC, Ramichotti, Brain Foundation and Sydney Childrens Hospital Foundation funding bodies. She was awarded her MD for publications in epilepsy in 1996. Current Research Projects:. 1) The diagnostic yield of a genomic approach to infantile epileptic encephalopathy. 2) Paediatric Epilepsy Network. This is a major project to raise minimal standards of care in management of paediatric epilepsy across NSW. This work commenced in 2010. It has been funded by NSW Health (Statewide ...
ABSTRACTPatients with refractory epilepsy face an elevated risk of sudden death, with rates as high as 1% per year. This phenomenon, known as sudden unexpected death in epilepsy (SUDEP), is believed to be a seizure-related occurrence, but the exact underlying mechanisms are uncertain. Both pulmonary and cardiac pathophysiologies have been proposed. The cardiac mechanism of greatest interest is the precipitation of arrhythmias by seizure discharges via the autonomic nervous system. SUDEP prevention has centered on effective seizure control, and epilepsy surgery has reduced SUDEP incidence in a number of studies. Additional prophylaxis methods are needed, however, for the large number of patients with treatment-refractory epilepsy. Future research should aim to clarify whether the association between seizures and autonomic dysfunction and cardiac arrhythmias extends to a demonstrable cardiac mechanism for SUDEP.
OBJECTIVES: The prognostic value of acute postoperative seizures (APS) after epilepsy surgery is much debated. This study evaluated APS, defined as seizures in the first week post-surgery, as a predictor of long-term seizure outcome, and investigated the utility of other potential outcome predictors.. MATERIALS AND METHODS: Medical records of 48 patients with temporal and extra-temporal epilepsy surgery were studied. Forty patients had lesional surgery. All had at least 2 year postoperative follow-up.. RESULTS: At 2 year follow-up, 25 patients (53%) were seizure free. Univariate analysis showed that APS (P = 0.048), using ≥ six AEDs prior to surgery (P = 0.03), pathological postoperative EEG (P = 0.043) and female gender (P = 0.012) were associated with seizure recurrence.. CONCLUSIONS: Univariate analysis indicate that APS, a high number of AEDs used prior to surgery, and pathological postoperative EEG are possible predictors of seizure recurrence after epilepsy surgery. Only gender retained ...
FRIDAY, April 17, 2020 (HealthDay News) -- The main focus of epilepsy treatment is seizure control, but the aftereffects of seizures are also a major concern for many patients, experts say.. More than 70% of people with epilepsy say they have complications after a seizure -- including confusion, fear, exhaustion, headache, emotional reactivity, memory problems and behavioral changes -- that can last for hours or days, according to the International League Against Epilepsy.. In most cases, there are no treatments for these complications and why they occur is poorly understood. Currently, preventing seizures that trigger these complications is the only option.. Complications such as fear and confusion after a seizure can sometimes cause a patient to become aggressive if a bystander or first responder doesnt understand how to interact with a person whos just had a seizure, according to the league.. Fear and confusion are so common after a seizure that many epilepsy centers have had ...
Epilepsy is a chronic disorder that often requires long-term antiepileptic drug treatment; unfortunately, these drugs can have long-term side effects. Until recently, many physicians were reluctant to discontinue antiepileptic drugs because the risk for seizure recurrence was thought to be dangerously high. The study by Berg and Shinnar suggests that patients may have a better chance of remaining seizure-free than previously thought. By using meta-analysis, the authors evaluated a comprehensive group of primary studies that focused on seizure relapse after discontinuation of antiepileptic drugs. The review was carefully designed with no important methodologic problems. The risk for seizure relapse after antiepileptic drug withdrawal at 1 year was 25%, which represents the lowest risk for recurrence in patients with the most favorable clinical features. Berg and Shinnar assessed 3 clinical features that modified the recurrence risk. The risk was increased for adult- and adolescent-onset compared ...
Purpose: To study long-term postoperative course and identify predictors for postoperative seizure control in patients with medically intractable temporal lobe epilepsy (TLE) associated with hippocampal sclerosis (HS), diagnosed by magnetic resonance imaging (MRI), and ascertained histopathologically. To compare patients becoming seizure-free (i.e., cured from epilepsy) and patients experiencing prolonged seizure-free periods interposed with recurring seizures.. Methods: One hundred thirty-five patients (74 women) underwent complete evaluation for epilepsy surgery. The predictive value of duration of epilepsy, age at onset, age at surgery, gender, febrile convulsion history, ictal dystonic posturing, unilateral interictal electroencephalography (EEG) discharges (IED), preoperative secondarily generalized tonic-clonic seizures (SGTCS), and preoperative seizure frequency for short- and long-term postoperative seizure control were evaluated with two classification systems: Classification 1 ...
One of Epilepsy Irelands key objectives is to undertake, encourage and fund research into all aspects of epilepsy. Epilepsy mortality has been identified as a key area where high calibre research is urgently needed worldwide and even within Ireland , there are many researchers with the interest and expertise to conduct this much needed research. Epilepsy Ireland has partnered with UK charity SUDEP Action and with UCC and Sheffield University to set up the Epilepsy Deaths Register for Ireland. The Register is based on the UK Epilepsy Deaths register launched in 2013 and shares much of the same infrastructure and personnel. The Epilepsy Deaths Register for Ireland was launched in 2015 and will provide:. ...
WEDNESDAY, Nov. 16, 2016 (HealthDay News) -- Some children born to mothers with rheumatoid arthritis may have higher-than-average odds of developing epilepsy, a new study suggests.. Children born to mothers with rheumatoid arthritis were one-third more likely to develop epilepsy by age 4 than other children. The risk of epilepsy later in childhood was one-quarter higher for those born to moms with rheumatoid arthritis, the study found.. But, experts stressed that the findings dont prove that a mothers rheumatoid arthritis causes epilepsy. So far, only an association has been found.. And even if children of women with rheumatoid arthritis have a higher epilepsy risk than other kids do, the odds are still low.. In the study of nearly 2 million children, the vast majority of those born to moms with rheumatoid arthritis did not develop epilepsy, said lead researcher Ane Lilleore Rom, of Copenhagen University Hospital in Denmark.. Still, she said, the findings raise the possibility that when a ...
The Report on Epilepsy in Latin America and the Caribbean (2013) prepared by the Pan American Health Organization (PAHO/WHO) with the support of the International League against Epilepsy and the International Bureau for Epilepsy is now available. Spanish , English. ...
Through story books and movies, the world has often wondered what it might be like to read minds, but rarely has epilepsy played a role in this vision until now. Scientists are making breakthroughs every day in the studies of how the human brain works, but Neurologist Josef Parvizi of the Department of Neurology and Neurological Sciences at Stanford, along with his team of researchers, have worked with Epilepsy patients for their latest breakthrough.. The struggle that those with epilepsy work with is immediately felt by those that know someone touched by the disorder. Epilepsy is considered a disorder rather than a disease due to the fact it is not directly contagious in any way. Those in extreme cases can experience one or two grand mal seizures a month regardless of whether they are at home, work or even on the streets. The seizures are brought on by sudden changes in how the brain works. Over half of the cases of epilepsy are from unknown causes. The causes that are known include, stroke, ...
Post-traumatic epilepsy (PTE) is a form of epilepsy that results from brain damage caused by physical trauma to the brain (traumatic brain injury, abbreviated TBI). A person with PTE suffers repeated post-traumatic seizures (PTS, seizures that result from TBI) more than a week after the initial injury. PTE is estimated to constitute 5% of all cases of epilepsy and over 20% of cases of symptomatic epilepsy (in which seizures are caused by an identifiable organic brain condition). It is not known how to predict who will develop epilepsy after TBI and who will not. However, the likelihood that a person will develop PTE is influenced by the severity and type of injury; for example penetrating injuries and those that involve bleeding within the brain confer a higher risk. The onset of PTE can occur within a short time of the physical trauma that causes it, or months or years after. People with head trauma may remain at a higher risk for seizures than the general population even decades after the ...
Definition of focal epilepsy in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is focal epilepsy? Meaning of focal epilepsy as a legal term. What does focal epilepsy mean in law?
Nationally renowned pediatric epilepsy expert joins team Beaumont Childrens neuroscience team is the first in Michigan to establish a Pediatric Stereo-electroencephalography Epilepsy Surgery Program. Stereo-electroencephalography, also known as SEEG, is a minimally invasive diagnostic EEG within the skull that pinpoints the source of seizures. It replaces a craniotomy with smaller incisions - 2mm holes in the skull. In the traditional approach - the subdural EEG, a neurosurgeon removes a large part of the skull for EEG electrode implantation, explained Pramote Laoprasert, M.D., director of Beaumont Childrens Comprehensive Epilepsy Center. SEEG can identify the source of seizures deep within the brain without removing a part of the skull. It reduces surgery and anesthesia time. Patients experience much less pain with less medication and a faster recovery time, typically within 24-48 hours. SEEG performed with ROSA, a robotic assistance system, is more precise and a less invasive option of ...
It is not yet clear, however, whether the epilepsy is usually caused by hippocampal abnormalities or whether the hippocampus is ... Seizures in temporal lobe epilepsy can affect the normal development of new neurons and can cause tissue damage. Hippocampal ... Kuruba R, Hattiangady B, Shetty AK (Jan 2009). "Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy". ... Damage to the hippocampus can also result from oxygen starvation (hypoxia), encephalitis, or medial temporal lobe epilepsy. ...
... epilepsy; floods; fruit dealers; fullers; gardeners; a holy death; mariners; market carriers; motorists and drivers; sailors; ...
... epilepsy; fetal alcohol syndrome disorders (FASD); generalized anxiety disorder; hearing impairment; hydrocephalus; limb ...
"Epilepsy". Mchb.hrsa.gov. Archived from the original on 2014-01-01. Retrieved 2013-12-31. "Early Childhood Programs". Mchb.hrsa ... Autism and Epilepsy Grants to improve health care and other services for children and adolescents with autism spectrum ...
July 2012). "Validation of the Subjective Handicap of Epilepsy (SHE) in Brazilian patients with epilepsy". Epilepsy & Behavior ... Epilepsy. The Epilepsy Surgery Inventory 55 (ESI-55) was developed at the University of California and covers eleven health ... Selai CE, Elstner K, Trimble MR (January 2000). "Quality of life pre and post epilepsy surgery". Epilepsy Research. 38 (1): 67- ... Vickrey BG (1993). "A procedure for developing a quality-of-life measure for epilepsy surgery patients". Epilepsia. 34 Suppl 4 ...
His PhD thesis was on the stigma experienced by adults with epilepsy living in the community. He was appointed Lecturer in ... London: Tavistock Scambler, G. (1989). Epilepsy. London: Tavistock Scambler, A. & Scambler, G. (1993). Menstrual disorders. ...
"Epilepsy". Facebook.com. Retrieved 22 May 2019. "The wonderwoman against epilepsy". Zimbanice.co.zw. Retrieved 22 May 2019. " ... So they need to speak out and share what they go through from what they know," said Lipsy Epilepsy is a chronic disorder of ... A person is diagnosed with epilepsy if they have two unprovoked seizures (or one unprovoked seizure with the likelihood of more ... she told of how society had shunned her and how she had lost friends because of the epilepsy. and it has impacted on her career ...
... definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)". ... In epilepsy, seizures have a tendency to recur and, as a rule, have no immediate underlying cause. Isolated seizures that are ... "Epilepsy Fact sheet". WHO. February 2016. Archivedfrom the original on 11 March 2016. Retrieved 4 March 2016. Fisher R, van ... Epilepsy - is a group of neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures are episodes ...
Seizure: European Journal of Epilepsy is a peer-reviewed medical journal covering epilepsy established in 1992. The editor-in- ... Official website Epilepsy Action (Articles with short description, Short description matches Wikidata, 10 times per year ... "Epilepsy". NLM Catalog. National Center for Biotechnology Information. PsycINFO Journal Coverage, American Psychological ... chief is Markus Reuber (University of Sheffield). It is the official journal of Epilepsy Action. It is published ten times a ...
Coppola, Antonietta; Moshé, Solomon L. (2012). "Animal models". Epilepsy. Handbook of Clinical Neurology. Vol. 107. pp. 63-98. ...
Rogawski M (1996). "Epilepsy". In Pullan L, Patel J (eds.). Neurotherapeutics: Emerging Strategies. Humana Press. pp. 193-273. ... In addition, at low, nontoxic doses, the drug has anti-absence activity in a genetic model of generalized absence epilepsy. ...
"Epilepsy". www.ukdmc.org. UK diving medical committee. Retrieved 31 December 2019. "Can I dive with Epilepsy?". DDRC healthcare ... Epilepsy is a central nervous system disorder in which the person has had at least two seizures, often for no discernible cause ... If epilepsy is required to be controlled by medication, diving is contraindicated. A possible acceptable risk would be a ... Even if no one with a history of epilepsy dived, a few people would experience their first seizure while diving. As a seizure ...
The exact causes of epilepsy are not fully known or understood, but it is thought to be caused by a chemical imbalance in the ... Because, however, the cause of epilepsy is centred in the brain, there was doubt for some time as to whether or not it should ... A case in which a defence relying on epilepsy succeeded is R v Mkize. Mkize was an epileptic. One day, while cutting meat with ... The court accepted that the nature of his epilepsy was such that he would not normally have realised or foreseen the dangers of ...
... epilepsy; movement disorders such as Parkinson's disease; headache and concussion treatment; trauma; injuries; and more. Norton ...
... epilepsy. May impair ability to drive or operate machinery. CNS depression including slight drowsiness to deep sleep, lassitude ...
"Seizure First Aid , Epilepsy , CDC". www.cdc.gov. 2020-09-30. Retrieved 2021-12-08. Pavitt MJ, Swanton LL, Hind M, et al. (12 ... Seizing can occur for a multitude of reasons but is common in those diagnosed with epilepsy. During a seizure, victims may ... people with epilepsy, and people on the autism spectrum. They may require more assistance to feed themselves, and it may be ...
Risks were listed as death due to cerebral haemorrhage or infection; epilepsy; and personality changes. A text book of the day ...
... epilepsy; learning problems; cognitive disabilities - mild to moderate; developmental delay - mild to moderate (milestones like ...
... epilepsy; acute or chronic glaucoma; and some forms of intractable pain." The initiative also allowed the state to add new ...
"Epilepsy". Online Etymology Dictionary. "Nymphai". Theoi Project. "Thera". World History Encyclopedia. "Santorini to the Cave ... ", "beautiful young woman", then "semi-divine being in the form of a beautiful maiden", and epilepsy, from the Greek word ...
Another common cause is epilepsy. According to Medlineplus epilepsy can be described as a brain disorder that causes seizures ( ... for the Study of Epilepsy and the care and treatment of Epileptics, 22 Nov 1904: 'That is to say the psyche may take on an ... "Epilepsy". Retrieved 5 December 2013. Revonsuo, Antti; Kallio, Sakari; Sikka, Pilleriin (April 2009). "What is an altered state ... as it was in relation to epilepsy, and is still used today. In academia, the expression was used as early as 1966 by Arnold M. ...
Epilepsy; "Lemons"; Inventors' Fair; Cuttlefish (December 2, 1989) DNA; Rube Goldberg Contest; Parrot Chat; Chewing Tin Foil; ...
Epilepsy Research. 46 (3): 241-250. doi:10.1016/S0920-1211(01)00280-7. ISSN 0920-1211. PMID 11518625. Kryger (2017). Principles ...
Moshé, editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. (2006). Models of seizures and epilepsy. Amsterdam: Elsevier ... Epilepsy Research. 23 (3): 189-194. doi:10.1016/0920-1211(95)00094-1. PMID 8739122. S2CID 21818415. Hradetzky, Eva; et al. (28 ... video-EEG monitoring has documented the presence of spontaneous electrographic seizure activity In some epilepsy rat models, ... which reduces DNA synthesis used in making animal models of neurological diseases including schizophrenia and epilepsy. MAM is ...
Stafstrom CE (2007). "Persistent Sodium Current and Its Role in Epilepsy". Epilepsy Currents. 7 (1): 15-22. doi:10.1111/j.1535- ...
Hart EJ (May 1990). "Nintendo epilepsy". The New England Journal of Medicine. 322 (20): 1473. doi:10.1056/NEJM199005173222020. ...
Hystero-epilepsy is a historical term that refers to a condition described by 19th-century French neurologist Jean-Martin ... The most definitive test to distinguish epilepsy from PNES is long term video-EEG monitoring, with the aim of capturing one or ... Features that are common in PNES but rarer in epilepsy include: biting the tip of the tongue, seizures lasting more than two ... 19 (3 Epilepsy): 715-29. doi:10.1212/01.CON.0000431399.69594.de. PMID 23739106. S2CID 30032816. LaFrance WC, Baker GA, Duncan R ...
... but has been shown that meningitis can cause epilepsy, which would give rise to the possibility of developing epilepsy ... Epilepsy most often occurs at the extremes of life - in childhood or in very old age - but can develop at any time throughout ... These infections are most likely to result in epilepsy when they occur at an early age. Problems with brain development can ... If a seizure happens during the infection itself, the person most likely doesn't have epilepsy but has "symptomatic seizures" ...
Epilepsy Res. 34 (2-3): 177-86. Sheehan, JJ; Benedetti, BL; Barth, AL (2009). "Anticonvulsant effects of the BK-channel ...
Garga N, Lowenstein DH (2006). "Posttraumatic epilepsy: A major problem in desperate need of major advances". Epilepsy Curr. 6 ... Pitkänen A, McIntosh TK (2006). "Animal models of post-traumatic epilepsy". Journal of Neurotrauma. 23 (2): 241-261. doi: ...
... such as how many people have epilepsy and the annual cost of epilepsy. ... Learn basic information about epilepsy in the United States, ... Who Has Epilepsy?. Active Epilepsya. In 2015, 1.2% of the total ... What Is Epilepsy?. Epilepsy is a disorder of the brain that causes seizures. These seizures are not caused by a temporary ... a Active epilepsy is defined as adults, participating in the 2015 NHIS, who reported a history of doctor-diagnosed epilepsy or ...
The FDA has cleared the first smart watch for seizure tracking and epilepsy management. The device uses advanced machine ... Embrace was tested in a clinical study involving 135 patients with epilepsy who were admitted to epilepsy monitoring units for ... Minorities With Epilepsy Blocked From Receiving Highest Quality of Care * Modified Atkins Diet Beneficial in Drug-Resistant ... "The FDA approval of the Embrace device to detect major convulsive seizures represents a major milestone in the care of epilepsy ...
Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, ... Epilepsy and Pregnancy (American Academy of Family Physicians) Also in Spanish * Epilepsy and Pregnancy: What You Need to Know ... Epilepsy - children (Medical Encyclopedia) Also in Spanish * Epilepsy - children - discharge (Medical Encyclopedia) Also in ... Epilepsy Data and Statistics (Centers for Disease Control and Prevention) * Epilepsy Fast Facts (Centers for Disease Control ...
The exact prevalence of autoimmune causes of epilepsy is not known. According to Dr Britton, a few studies have suggested that ... Dr Carreños own study of 13 patients with drug-resistant epilepsy due to autoimmune encephalitis showed that surgery may be a ... "Over the past few years, there has been increasing recognition that some forms of epilepsy are immune mediated; theyre ... At a press briefing during the American Epilepsy Society (AES) 69th Annual Meeting here, Dr Steriade presented a study ...
Epilepsy. Temporal lobe epilepsy. Frontal lobe epilepsy. Rolandic epilepsy. Sleep-related hypermotor epilepsy. Panayiotopoulos ... "Abdominal Epilepsy in Children and Adults". Epilepsy Health Center. WebMD. 18 March 2013. Retrieved 13 February 2014.. ... Autonomic epilepsy. Abdominal epilepsy is a rare condition most frequently found in children, consisting of gastrointestinal ... Like other forms of epilepsy, abdominal epilepsy is treated with anticonvulsant drugs, such as phenytoin. Based on the clinical ...
249 Crumlin Rd, Dublin 12, D12RW92, Ireland , Tel +353 1 455 7500 , [email protected]epilepsy.ie , © Epilepsy Ireland , Registered Charity ... Questions or concerns about epilepsy?. Contact us on +353 1 455 7500 or [email protected]epilepsy.ie. ... From an Epilepsy Ireland perspective, using the funds raised, we hope to extend SUDEP Actions renowned SUDEP and Seizure ... Their extraordinary efforts aim to raise funds for both Epilepsy Ireland and our colleagues in SUDEP Action. Although the cycle ...
In approximately 1/3 of patients with epilepsy, seizures persist despite adequate trials of several antiepileptic drugs (AEDs ... juvenile absence epilepsy, juvenile myoclonic epilepsy, generalized epilepsy and febrile seizures plus, and various progressive ... frontal lobe epilepsies (several locations), parietal lobe epilepsies, occipital lobe epilepsies, and Rasmussen encephalitis ... Anesthesia in Epilepsy Surgery. Engel J Jr, ed. Surgical Treatment of the Epilepsies. 2nd ed. New York, NY: Raven Press; 1993. ...
Epilepsy Employment Group (EEG) is a Job Search Support Group. Join in and meet some new people, swap points of view and learn ... Epilepsy Employment Group (EEG) is a Job Search Support Group for people living with epilepsy. This group is meeting online via ... Epilepsy Toronto offers services on the traditional territory of many nations including the Mississaugas of the Credit, the ... For more infomation or to rsvp for the next Epilepsy Employment Group, contact Carter at [email protected] and well ...
Science News was founded in 1921 as an independent, nonprofit source of accurate information on the latest news of science, medicine and technology. Today, our mission remains the same: to empower people to evaluate the news and the world around them. It is published by the Society for Science, a nonprofit 501(c)(3) membership organization dedicated to public engagement in scientific research and education (EIN 53-0196483).. ...
Drivers With Epilepsy: Balancing Quality of Life and Public Safety Guidelines issued by professional societies and advocacy ... Paul Gringras, MD, on the Two-way Street of Epilepsy and Sleep This expert discusses the common, often highly disruptive ... Accidental Death and Suicide in Patients with Epilepsy: Scope of the Problem A new study advances our knowledge about the ... Ask the Expert: Andres M. Kanner, MD on Psychiatric Comorbidities in Patients with Epilepsy Andres Kanner, MD, shares ways to ...
Some people who suffer from epilepsy believe that marijuana stops their seizures. Two compounds found in the drug, THC and CBD ... Facts about seizures and epilepsy (2013).. epilepsy.com/learn/epilepsy-101/facts-about-seizures-and-epilepsy. ... Epilepsy is a nervous system disorder that causes seizures. Absence seizures, also called petit mal seizures, are brief and may ... Many people with epilepsy can manage their seizures with proper medications and treatment. Get facts about the long-term ...
... is a medical condition that occurs when a person has recurring seizures. It is also called a ... There is research to suggest that one or more genes may cause epilepsy. Other causes of epilepsy may include:. *Infections of ... The exact cause of epilepsy varies. In some people, there is no clear cause of epilepsy. ... What is Epilepsy? Seizures are caused by sudden, abnormal activity in the brain. In many cases, seizures are just a onetime ...
The misdiagnosis of epilepsy The rate of misdiagnosis and wide treatment choices are arguments for specialist care of epilepsy ... The misdiagnosis of epilepsy. BMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7336.495 (Published 02 March 2002) Cite this ...
That was over a year ago, and since then my family has been living with epilepsy. I know now that what she had was called a ... Canine epilepsy is common in certain breeds, particularly collies and poodles. While there is no cure, it is definitely a ... Belles on medication now, phenobarbitol (the most common med given to dogs with epilepsy). She is still having seizures, ...
Our Comprehensive Epilepsy Genetics Program can help us diagnose and treat patients with epilepsy who have a family history or ... Resources from our Epilepsy Education Series ​. *Canada Revenue Agency (CRA) Benefits. *Canada Pension Plan - Useful Resources ... Epilepsy is a disease where there is still a lot of misunderstanding. At the Krembil Brain Institute, we know about the ... Epilepsy Pregnancy Clinic. Treatments. Multiple treatment options are available at the Krembil Brain Institute. In addition to ...
Anyone can get epilepsy at any point in their life. Over 1 % of Finns with epilepsy are over 65-year-old, which is more than ... For some, epilepsy has been present since childhood. Some get ill at an older age. The reasons for epilepsy can be common ... An open attitude to epilepsy reduces prejudice and makes it easier to cope. Others who live with epilepsy can give different ... You can find more detailed information in Finnish on the Terveyskylä.fi -website about epilepsy and epilepsy in older adults. ...
Estimate of annual incidence of epilepsy are as high as 43 cases per 100,000 of the population in so-called developed countries ... The cumulative lifetime risks for epilepsy and for any unprovoked seizure are 3.1% and 4.1%, respectively, in industrialized ... Epilepsy is a common disease. The cumulative lifetime risks for epilepsy and for any unprovoked seizure are 3.1% and 4.1%, ... Within this there is a growing appreciation of gender differences in the epidemiology of epilepsy and of specific epilepsy ...
Help Becca Garner raise money to support Epilepsy Action ...
Frontal lobe epilepsy is characterized by recurrent seizures arising from the frontal lobes. Frequently, seizure types are ... Outcome of frontal lobe epilepsy surgery in adults. Epilepsy Res. 2008 Oct. 81 (2-3):97-106. [QxMD MEDLINE Link]. ... Brodtkorb E, Picard F. Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy. Epilepsy Behav. 2006 Nov. 9( ... encoded search term (Frontal Lobe Epilepsy) and Frontal Lobe Epilepsy What to Read Next on Medscape ...
Understanding Epilepsy Main Menu * What is Epilepsy? * Understanding Seizures * Who Can Get Epilepsy?. ... Living With Epilepsy Main Menu * Tracking & Managing Seizures * Managing Triggers * How to Indentify Seizure Triggers. ... ️ 2022 Epilepsy Foundation®️, is a non-profit organization with a 501(c)(3) tax-exempt status. Tax ID: 52-0856660 ... Please join Camila, Cynthia and many, many more in this brave act of standing up against epilepsy. The eJourney is yours, and ...
... including how to help a child deal with epilepsy and tips for medicine. ... Find information and more about epilepsy in children from Cleveland Clinic, ... Epilepsy in Children This article details common concerns facing a parent who has a child with epilepsy, and how to handle them ... Children with epilepsy might be teased by other children.) Anxiety and depression are seen frequently in children with epilepsy ...
2019)‎. Epilepsy and seizures. World Health Organization. Regional Office for the Eastern Mediterranean. https://extranet.who. ...
... epilepsy - Sharing our stories on preparing for and responding to public health events ... Tags epilepsy, preparedness Loving Someone With Epilepsy. When Zayan first told me that he has epilepsy, I didnt believe him ... Epilepsy and Emergency Preparedness. November is National Epilepsy Awareness Month Epilepsy is common. In 2015, about 3.4 ... Epilepsy is a broad term used for a brain disorder that causes repeated seizures. There are many different types of epilepsy. A ...
Examine the company profile of Epilepsy Foundation New England and learn about Epilepsy Foundation New England jobs and career ...
Epilepsy, grand mal: Epilepsy that includes tonic-clonic (grand mal) seizures, which are the most obvious type of seizure. ... What Is Epilepsy? Symptoms, Causes, and Treatments See Slideshow From Brain & Nervous Resources. *11 Tips for Avoiding Seizure ... Read medical definition of Epilepsy, grand mal ... Definition of Epilepsy, grand mal. *Medical Editor: Melissa ...
... Dispelling the Top 5 Epilepsy Myths Although much is still unknown about epilepsy, experts agree that these ... Nutrition Epilepsy Erectile Dysfunction Fitness & Exercise Flu Treatment Healthy Aging & Retirement Heart Health Heartburn & ...
Find out everything you need to know about epilepsy including symptoms, treatment, causes, management and more. ... Health Topicsbrain-health-nervous-systemEpilepsy. Epilepsy. Find out everything you need to know about epilepsy including ... What Is Epilepsy?. Epilepsy is a nervous system disorder and there are three different types of it. In this video, fami.... ... What Causes Epilepsy?. A few different things can cause epilepsy including genetics and infections. In this video, family p... ...
Children dont always understand the potential perceptions and implications of their actions, Center Grove officials said in a letter to parents.
Sudden unexpected deaths in epilepsy have proven difficult to unravel. A recent study concludes that they might be driven by ... What to know about epilepsy. Medically reviewed by Heidi Moawad, MD. Epilepsy is a fairly common neurological condition ... Uncontrolled epilepsy is the primary risk factor for sudden unexpected death in epilepsy (SUDEP). ... their findings in the journal Epilepsy Research.. The team was headed up by Prof. Pedro Irazoqui who was inspired by his own ...
  • The International League Against Epilepsy has updated its classification of seizure types in large part to clarify terminology, categorize certain seizure types as either focal or generalized, and classify seizures when the onset is unknown. (medpagetoday.com)
  • In 1993, the International League Against Epilepsy (ILAE) proposed simplified classification guidelines to facilitate epidemiologic work in epilepsy, and to allow meaningful comparison between studies undertaken at different times and in different parts of the world. (nih.gov)
  • In this review, the development of the current classification of epilepsy syndromes will be discussed, followed by the recent efforts of the International League Against Epilepsy Commission on Classification and Terminology to address necessary changes in diagnostic categories and the conceptual framework that gives rise to these groupings. (semanticscholar.org)
  • The International League Against Epilepsy presents a revised operational classification of seizure types to recognize that some seizure types can have either a focal or generalized onset, to allow classification when the onset is unobserved, to include some missing seizure types, and to adopt more transparent names. (semanticscholar.org)
  • An International League Against Epilepsy task force has evaluated the need for revising the current classification and terminology and has begun developing four specific documents, including a classification of epileptic seizures based on known or presumed pathophysiological and anatomic substrates. (semanticscholar.org)
  • In 2014, the International League Against Epilepsy Epilepsy Guidelines Task Force expanded the practical definition of epilepsy to include having at least two unprovoked seizures more than 24 hours apart, having one unprovoked seizure and a probability of further seizures of at least 60%, and a diagnosis of an epilepsy syndrome. (medscape.com)
  • These data are part of a systematic review from the Mortality Task Force of the International League Against Epilepsy from 2017. (mentalhealthandmedicine.org)
  • The burden of premature mortality of epilepsy in high-income countries: A systematic review from the Mortality Task Force of the International League Against Epilepsy. (mentalhealthandmedicine.org)
  • [ 6 ] and has been adopted by the International League Against Epilepsy (ILAE). (medscape.com)
  • Tragically, more than 3000 Americans die each year from sudden unexpected death in epilepsy (SUDEP) and the Embrace offers the potential to alarm family members and caretakers that a tonic-clonic seizure is occurring. (medscape.com)
  • The Cycle for Shane was set up in memory of the late Shane Corrigan - who sadly passed away from Sudden Unexpected Death in Epilepsy (SUDEP) in January 2018. (epilepsy.ie)
  • The American Academy of Neurology and the American Epilepsy Society created new evidence-based practice guidelines on sudden unexpected death in epilepsy. (medpagetoday.com)
  • These include the incidence of status epilepticus (more common in men), incidence of sudden unexpected death in epilepsy (SUDEP), prognosis, and mortality. (nih.gov)
  • Could acid reflux explain sudden unexpected death in epilepsy? (medicalnewstoday.com)
  • Uncontrolled epilepsy is the primary risk factor for sudden unexpected death in epilepsy (SUDEP). (medicalnewstoday.com)
  • This is very unique and not seen in other types of epilepsy. (medscape.com)
  • There are many different types of epilepsy. (cdc.gov)
  • Parents of children with epilepsy, especially the most severe types of epilepsy, are desperate for a deeper understanding of the causes of the problems and for the development of new treatments. (news-medical.net)
  • It revealed which of the many types of epilepsy had a genetic basis, and which didn't, so as to better target their gene discovery studies. (futurity.org)
  • This paper explores how the indications of the diet changed together with the shifting focus of epilepsy teams towards its use in different types of epilepsy and epilepsy syndromes and according to etiologies and as an alternative option in refractory and superrefractory status epilepticus . (bvsalud.org)
  • (https://www.who.int/mental_health/neurology/epilepsy/report_2019/en/, accessed 12 October 2019). (who.int)
  • Patients with autoimmune epilepsy may benefit from early-initiated immunotherapy, shows study published in Archives of Neurology. (medindia.net)
  • To evaluate clinical characteristics and immunotherapy responses in patients with autoimmune epilepsy, Amy M. L. Quek, M.B.B.S., of the Mayo Clinic, College of Medicine, Rochester, Minn., and colleagues, gathered data from the Mayo Clinic computerized diagnostic index from patients who were evaluated in both the Autoimmune Neurology Clinic and Epilepsy Clinic between January 2005 and December 2010, and were diagnosed with autoimmune epilepsy. (medindia.net)
  • The patient had not responded to any surgical or other treatment and had run out of options,' Director of Epilepsy and EEG Service and Deputy Director of the Neurology Department in Sheba Prof. Nicola Maggio said. (ynetnews.com)
  • All patients diagnosed with epilepsy through BMC's pediatric neurology department will be given the choice of creating a virtual care plan via the platform go.ACT.md . (bmc.org)
  • All patients admitted to the Epilepsy Monitoring Unit or who attended the Neurology OPD in Beaumont Hospital with treatment resistant epilepsy are considered a candidate for inclusion. (rcsi.com)
  • Today, I have the pleasure of speaking with Dr Jacqueline French, professor of neurology and epileptologist at NYU Comprehensive Epilepsy Center. (medscape.com)
  • Within this there is a growing appreciation of gender differences in the epidemiology of epilepsy and of specific epilepsy syndromes. (nih.gov)
  • Also, the behavior of some common epilepsy syndromes such as mesial temporal sclerosis may differ between genders with isolated auras more common among females and secondary seizure spread more likely in males. (nih.gov)
  • The role of EEG in the diagnosis and classification of the epilepsy syndromes: a tool for clinical practice by the ILAE Neurophysiology Task Force (Part 1). (medscape.com)
  • The present review discusses the issues related to several of these epilepsy syndromes in childhood, including Dravet's Syndrome, West Syndrome, Lennox-Gastaut Syndrome, Myoclonic Astatic Epilepsy, and Landau-Kleffner Syndrome. (semanticscholar.org)
  • Many different conditions or syndromes can cause epilepsy. (phoenixchildrens.org)
  • Juvenile myoclonic epilepsy (JME) is one of the most common idiopathic (genetic) generalized epilepsy (IGE) syndromes. (medscape.com)
  • It is important to view IGE as a spectrum of genetic epilepsies with individual syndromes (such as JME) but with significant overlap. (medscape.com)
  • In the "ILAE Definition of the Idiopathic Generalized Epilepsy Syndromes: Position Statement by the ILAE Task Force on Nosology and Definitions," JME is defined as "the most common adolescent and adult onset IGE syndrome and is characterized by myoclonic and generalized tonic-clonic seizures in an otherwise normal adolescent or adult. (medscape.com)
  • When idiopathic partial epilepsy syndromes were excluded, the 5 pairs accounted for 23% of monozygotic pairs with partial epilepsies, and 38% of monozygotic pairs with partial epilepsy and no known etiology . (symptoma.com)
  • 2019)‎. Epilepsy and seizures. (who.int)
  • From an Epilepsy Ireland perspective, using the funds raised, we hope to extend SUDEP Action's renowned SUDEP and Seizure Safety Checklist to Ireland. (epilepsy.ie)
  • This resource has widely been integrated into the care of people with epilepsy in the UK to help clinicians discuss SUDEP risk and to make people with epilepsy and their families more aware about SUDEP. (epilepsy.ie)
  • SUDEP affects an estimated 1 in 1,000 adults with epilepsy each year. (medicalnewstoday.com)
  • To address the challenges and gaps in providing care for people with epilepsy and other neurological disorders, the Seventy-fifth World Health Assembly (WHA) in May 2022 adopted the Intersectoral global action plan on epilepsy and other neurological disorders (IGAP), which aims to improve access to care and treatment for people living with neurological disorders while preventing new cases and promoting brain health and development across the life course. (who.int)
  • While marking the Epilepsy awareness challenge 2022, Fatima shared a mirror picture wearing a fuzzy trench coat, on her social media, while writing down a caption about Epilepsy that appeals to the mass audience as she also urged people to share their stories of epilepsy. (thestatesman.com)
  • I'm Dr Andrew Wilner, reporting virtually from the 2022 American Epilepsy Society meeting in Nashville, Tennessee. (medscape.com)
  • Mixed mood and anxiety disorders in conjunction with a genetic psychiatric history have been identified as factors of poorer seizure control in patients with mesial temporal lobe epilepsy. (medpagetoday.com)
  • Andres Kanner, MD, shares ways to expedite the diagnosis and management of mood and anxiety disorders among patients with epilepsy within the time constraints of a busy medical practice. (medpagetoday.com)
  • 2014). Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. (healthline.com)
  • The reasons for epilepsy can be common disorders in the brain, such as cerebrovascular diseases, brain tumors and degenerative diseases of the brain. (epilepsia.fi)
  • Genetic epilepsy refers to a number of seizure disorders (e.g. (rush.edu)
  • Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Epilepsy-Information-Page. (epnet.com)
  • As a result, WHO and other partners have been engaging stakeholders to share ideas towards the effective implementation of the Intersectoral global action plan on epilepsy and neurological disorders in Ghana. (who.int)
  • There is the need for collaboration between relevant stakeholders - everyone in healthcare at all levels, social care, advocacy and civil organizations, researchers, and academic institutions in a bid to improve services for epilepsy and other neurological diseases are in Ghana", noted WHO Representative to Ghana, Dr. Francis Kasolo at the stakeholders meeting on epilepsy and other neurological disorders in Ghana. (who.int)
  • We use sophisticated testing options for epilepsy, seizures and other brain disorders. (muschealth.org)
  • Although ADHD is present in focal and generalized epilepsies, some epileptic types or disorders, such as rolandic epilepsy and frontal epilepsy, were strongly associated with ADHD symptoms, especially in those individuals with newly diagnosed epilepsy, poorly controlled seizures, and abnormal electroencephalogram. (bvsalud.org)
  • Children with this type of epilepsy may have a family history of epilepsy. (rush.edu)
  • With this type of epilepsy children have typically been on at least two different medications at appropriate doses. (rush.edu)
  • There is not just one type of epilepsy. (dana.org)
  • Researchers at the Indian Institute of Science (IISc), in collaboration with All India Institute of Medical Sciences (AIIMS), Rishikesh, have developed an algorithm that they said can help decode brain scans to identify the occurrence and type of epilepsy. (thehindu.com)
  • The team ran their algorithm on a new set of EEG data from subjects for whom the classification (whether they had epilepsy, and if so, what type of epilepsy they had) was already known to the doctors. (thehindu.com)
  • We use testing to confirm an epilepsy diagnosis and determine the type of epilepsy with a high degree of accuracy. (muschealth.org)
  • Evaluating this activity helps us determine the type of epilepsy and which treatments may work best. (muschealth.org)
  • Like other forms of epilepsy, abdominal epilepsy is treated with anticonvulsant drugs, such as phenytoin . (wikipedia.org)
  • Cortical dysplasia, meaning disordered development of the cerebral cortex, is identified in 25 to 40 percent of children with the most severe and difficult-to-treat forms of epilepsy. (news-medical.net)
  • We study the gene "doublecortin," which is defective in some forms of epilepsy and mental retardation in humans," said Kerjan, lead author of the study. (news-medical.net)
  • But scientists found a genetic basis to specific forms of epilepsy, changing how its definition and treatment. (futurity.org)
  • This article details common concerns facing a parent who has a child with epilepsy, and how to handle them. (clevelandclinic.org)
  • Don't let a child with epilepsy swim alone. (clevelandclinic.org)
  • Parenting a child with epilepsy can be both rewarding and challenging. (sharecare.com)
  • The Rush Epilepsy Center focuses on selecting the best medication regimen for each child with epilepsy. (rush.edu)
  • Use these tips to make sure your child with epilepsy gets the care and support they need during the school day. (cdc.gov)
  • As your child with epilepsy returns to school, use these tips to ensure they get the care and support they need in school. (cdc.gov)
  • Use these tips to make sure your child with epilepsy has the support she needs to stay safe at school. (cdc.gov)
  • On the other hand, idiopathic generalized epilepsies (IGEs), which may represent some 15-20% of all epilepsies, are more common among females. (nih.gov)
  • If an underlying cause cannot be identified, a diagnosis of idiopathic or primary epilepsy is made. (uk.net)
  • Like all idiopathic (genetic) generalized epilepsies (IGEs), juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy (GGE), and both IGE and GGE are acceptable terms according to ILAE. (medscape.com)
  • Like the entire group of idiopathic (genetic) generalized epilepsies (IGEs), genetic factors play a definite role, hence the term genetic generalized epilepsy (GGE). (medscape.com)
  • Rush's epilepsy program, in collaboration with the Epilepsy Foundation of North/Central Illinois, is developing portable communication technologies that will allow epileptologists to take specialized epilepsy care to children with refractory epilepsy in rural communities that lack this expertise. (rush.edu)
  • Data to date assessing psychopathology in refractory epilepsy patients is conflicting. (rcsi.com)
  • In a subgroup of medically refractory epilepsy patients, surgical intervention is considered. (rcsi.com)
  • This study is prospective cohort study which examined a group of patients with medically refractory epilepsy, and also examined a cohort who proceeded to surgery before and after surgery. (rcsi.com)
  • The findings of this study demonstrated the high prevalence of psychiatric comorbidity (49%) in patients with medically refractory epilepsy. (rcsi.com)
  • Overall, this study has demonstrated that undergoing surgery for medically refractory epilepsy had an overall positive Impact on mental health with a significant reduction in the severity and prevalence of psychiatric symptoms and an improved quality of life. (rcsi.com)
  • When clinical and serological clues suggest an autoimmune basis for medically intractable epilepsy, early-initiated immunotherapy may improve seizure outcome," the authors conclude. (medindia.net)
  • Intractable epilepsy refers to recurrent seizures that are not well controlled with medication. (rush.edu)
  • It is important to correctly diagnose medically intractable epilepsy in children and to identify those children whose medically refractory, localization-related seizures may be surgically remediable as soon as possible to optimize the surgical outcome. (medscape.com)
  • They also outline the presurgical diagnostic evaluation process for pharmacologically intractable epilepsy in children who may be candidates for surgical treatment of localization-related seizures. (medscape.com)
  • The treatment of children with medically intractable epilepsy is both challenging and rewarding. (medscape.com)
  • Cite this: Pharmacologically Intractable Epilepsy In Children: Diagnosis and Preoperative Evaluation - Medscape - Sep 01, 2008. (medscape.com)
  • Epilepsy Employment Group (EEG) is a Job Search Support Group for people living with epilepsy. (epilepsytoronto.org)
  • Statistics from the Centers for Disease Control and Prevention (CDC) show that more people are living with epilepsy in the United States than ever before. (intermountainhealthcare.org)
  • That was over a year ago, and since then my family has been living with epilepsy . (everything2.com)
  • From employment and transportation to education and housing, people living with epilepsy face these issues and many more on a daily basis. (epilepsyontario.org)
  • Canadians have spoken out about the social consequences and health obstacles they face while living with epilepsy. (epilepsyontario.org)
  • Many people living with epilepsy are reluctant to disclose their condition to co-workers or friends out of fear of what they might think. (epilepsyontario.org)
  • Our message is loud and clear: we want to improve the quality of life for the 140,000 Ontarians who are living with epilepsy. (epilepsyontario.org)
  • Transforming the lives of people living with epilepsy through world-leading research, advocacy and care. (runbritain.com)
  • AptarGroup, Inc. (NYSE: ATR), a global leader in drug delivery, consumer product dispensing and active packaging solutions, today announced that its patented Unidose Liquid System is the device delivering the first and only nasal rescue treatment approved by the U.S. FDA, which has recently launched in the U.S. to treat acute repetitive seizures in people living with epilepsy. (aptar.com)
  • Thank you for supporting people living with epilepsy! (epilepsyfoundation.org.au)
  • The scientists hope that their findings - based on a mouse model of severe epilepsy - may someday pave the way for improved treatments of childhood epilepsy, which affects more than two percent of children worldwide. (news-medical.net)
  • Through clinical trials, epilepsy experts at Rush also participate in the study of new medical treatments that are not otherwise widely available. (rush.edu)
  • For hard-to-treat epilepsy, testing enables us to plan your treatments meticulously. (muschealth.org)
  • No treatments could stop his epilepsy, so as a last resort surgeons removed a third of his brain 's right hemisphere just before his seventh birthday. (newscientist.com)
  • Over the nearly 100 years of use, from being a last resource in the therapeutic algorithm , the diet has become one of the four main treatments for patients with difficult-to- control epilepsy together with antiepileptic drugs , surgery , and vagus nerve stimulation . (bvsalud.org)
  • [8] Distinguishing features of abdominal epilepsy include (1) Abnormal laboratory, radiographic, and endoscopic findings revealing paroxysmal GI manifestations of unknown origin (2) CNS symptoms (3) Abnormal EEG . (wikipedia.org)
  • Abdominal epilepsy is marked by GI symptoms such as abdominal pain followed by uncontrollable vomiting , usually preceded by lethargy . (wikipedia.org)
  • Lethargy and confusion is the most common neurological symptoms associated with abdominal epilepsy. (wikipedia.org)
  • Criteria for diagnosis of abdominal epilepsy includes frequent periodic abdominal symptoms, an abnormal electroencephalogram (EEG) and significant improvement of gastrointestinal symptoms after taking anti-seizure medication. (wikipedia.org)
  • Symptoms that are persistent throughout or persist for hours are less probable to be indications of abdominal epilepsy. (wikipedia.org)
  • Convulsions, impairment in consciousness and other neurological symptoms are ought to be considered along with the gastrointestinal symptoms when diagnosing abdominal epilepsy. (wikipedia.org)
  • Find out everything you need to know about epilepsy including symptoms, treatment, causes, management and more. (sharecare.com)
  • Seizures, transient signs or symptoms caused by abnormal surges of electrical activity in the brain, can result from epilepsy, a neurologic disorder characterized by abnormal electrical brain activity causing recurrent, unprovoked seizures, or from other inciting causes, such as high fever or substance abuse. (medscape.com)
  • Patients with epilepsy may experience warning symptoms before a seizure. (nbc-2.com)
  • People with Lafora progressive myoclonus epilepsy generally survive up to 10 years after symptoms first appear. (medlineplus.gov)
  • Although Lafora bodies are found in many of the body's tissues, the signs and symptoms of Lafora progressive myoclonus epilepsy are limited to the nervous system. (medlineplus.gov)
  • People with Epilepsy, Parkinson's Disease, Attention Deficit Disorder (ADD) or addictions may be able to learn how to 'think themselves better' by altering their brain waves to improve their symptoms. (epilepsytalk.com)
  • Two of the children in each family demonstrated similar symptoms that can be connected to a severe variant of infant epilepsy with MPSI (Migrating Partial Seizures of Infancy). (ki.se)
  • METHODS: Subjects 18 or older with localization-related epilepsy (LRE) and =3 seizures per month maintained an e-diary, reporting a.m./p.m. data daily, including mood, premonitory symptoms, and all seizures. (cdc.gov)
  • The US Centers for Disease Control and Prevention estimates that about 3.4 million people in the United States have epilepsy, including 470,000 children. (medscape.com)
  • If your patient has not undergone diagnostic testing, search here to find a comprehensive epilepsy center that can evaluate your patient, including determining if the RNS System is right for them. (amazonaws.com)
  • Laboratory testing focussed on epileptic seizures in particular because of the challenges of long-term treatment with current anti-epileptic drugs and the large number of patients with drug-resistant epilepsy. (epilepsy.org.nz)
  • If you've been looking for an epilepsy camp in Texas for your child or a summer camp for epileptic adults , you've come to the right place. (campforall.org)
  • Our summer camp for epileptic children is staffed by people who are specially trained to work with kids who have epilepsy, so you can feel confident that your child is in a safe environment while expanding their horizons and developing confidence and independence. (campforall.org)
  • Epilepsy is defined as a brain disorder characterized by an enduring predisposition to generate epileptic seizures and by the neurobiologic, cognitive, psychological, and social consequences of this condition. (medscape.com)
  • If you hear the mother of someone with epilepsy saying, "Well, the seizure began with the individual's head turning far to the right-hand side, it got stuck there, then there was stiffening of one hand and the individual made a guttural noise, lost posture, and fell to the ground, and then stiffened all over and started to shake," you would be pretty sure that was an epileptic seizure. (medscape.com)
  • For the second consecutive year, the University of Minnesota, with help from the Epilepsy Foundation of Minnesota, is dedicating a game to raising awareness for a disease that affects 60,000 people in the state and 3 million nationwide. (twincities.com)
  • Cite this: FDA Clears First Smart Watch to Detect Seizures, Manage Epilepsy - Medscape - Feb 06, 2018. (medscape.com)
  • Adaptation and validation of QOLIE-31 were performed in July 2018 among 118 patients with epilepsy in the Fez-Meknes region. (who.int)
  • Lafora progressive myoclonus epilepsy is a brain disorder characterized by recurrent seizures (epilepsy) and a decline in intellectual function. (medlineplus.gov)
  • Epilepsy is one of the most common serious chronic neurological conditions affecting people of all ages globally, with peaks in incidence rates in children and in adults over the age of 60. (who.int)
  • Epilepsy is a neurological disease where the brain emits sudden bursts of electrical signals in a short amount of time. (thehindu.com)
  • Epilepsy is a neurological disordered characterized by recurring seizures. (somervillegardensnj.com)
  • The Rush pediatric epilepsy team focuses on helping children with epilepsy thrive and reach their fullest potential cognitively, emotionally and socially. (rush.edu)
  • Learn more about pediatric epilepsy providers at Rush. (rush.edu)
  • Epilepsy is a disorder of the brain that triggers recurrent seizures. (cdc.gov)
  • Epilepsy is described as the tendency to have recurrent seizures. (uk.net)
  • Embrace was tested in a clinical study involving 135 patients with epilepsy who were admitted to epilepsy monitoring units for continuous monitoring with video electroencephalography while simultaneously wearing the device, which records electrodermal activity. (medscape.com)
  • Subtypes of post-traumatic epilepsy: clinical, electrophysiological, and imaging features. (medscape.com)
  • Clinical trials are ongoing with a drug that, if successful, will compensate for the disrupted regulation and ameliorate the disease in small children with epilepsy, says Dr. Wedell. (ki.se)
  • My talk was getting people to pay attention to what the person is telling you to understand better about seizure type and presence or absence of epilepsy, and how that might relate to doing a very good, high-quality clinical trial. (medscape.com)
  • Yet, there's no specific test for epilepsy, so it's a clinical diagnosis. (medscape.com)
  • If you were able to capture a seizure on video EEG monitoring, that would be confirmation of a diagnosis of epilepsy. (medscape.com)
  • In the later stages of Lafora progressive myoclonus epilepsy, myoclonus often occurs continuously and affects the entire body. (medlineplus.gov)
  • Several types of seizures commonly occur in people with Lafora progressive myoclonus epilepsy. (medlineplus.gov)
  • The prevalence of Lafora progressive myoclonus epilepsy is unknown. (medlineplus.gov)
  • Lafora progressive myoclonus epilepsy can be caused by mutations in either the EPM2A gene or the NHLRC1 gene. (medlineplus.gov)
  • Researchers have discovered that people with Lafora progressive myoclonus epilepsy have distinctive clumps called Lafora bodies within their cells. (medlineplus.gov)
  • Mutations in the EPM2A and NHLRC1 genes account for 80 percent to 90 percent of all cases of Lafora progressive myoclonus epilepsy. (medlineplus.gov)
  • The study included patients with autoimmune epilepsy as the predominant neurologic feature, so their main presenting symptom was seizures. (medscape.com)
  • As previously mentioned, it is difficult to distinguish frontal lobe seizures from nonepileptic events based on history alone, and patients with frontal lobe epilepsy may be misdiagnosed as having psychogenic nonepileptic events. (medscape.com)
  • Brodtkorb E, Picard F. Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy. (medscape.com)
  • Incidence of sudden unexpected death in nocturnal frontal lobe epilepsy: a cohort study. (medscape.com)
  • The syndrome of frontal lobe epilepsy: characteristics and surgical management. (medscape.com)
  • Baud MO, Vulliemoz S, Seeck M. Recurrent secondary generalization in frontal lobe epilepsy: Predictors and a potential link to surgical outcome? (medscape.com)
  • Factors predictive of the outcome of frontal lobe epilepsy surgery. (medscape.com)
  • We plan to include and compare patients with temporal and frontal lobe epilepsy as well as healthy volunteers. (uniklinik-freiburg.de)
  • Pyridoxine-dependent epilepsy is caused by a specific genetic problem and starts when a child is a newborn or baby. (rush.edu)
  • Epilepsy may occur as a result of a genetic disorder or a brain injury, but many people never know the cause. (thestatesman.com)
  • The condition affects about 40 per cent of all epilepsy sufferers, about 100,000 Australians, and is caused by an electrical storm that emanates from a single point in the brain. (edu.au)
  • To demystify epilepsy-which affects almost four million people in the US-a doctoral candidate presented "The Science of Epilepsy" with explanations of how seizures work and what to do if someone is having one. (dana.org)
  • Why is there still so much stigma attached to epilepsy, which currently affects about one in 26 people in the US? (dana.org)
  • There is poor knowledge about epilepsy among teachers in Morocco, and this unawareness negatively affects teachers' attitudes towards people with epilepsy (8). (who.int)
  • FORT LAUDERDALE, Fla. (Ivanhoe Newswire) - Epilepsy affects three million people every day. (ivanhoe.com)
  • In 2016, a Maryland man was charged with aggravated assault with a deadly weapon after deliberately tweeting a strobing GIF to a journalist with epilepsy. (kivitv.com)
  • Fast Five Quiz: Test Your Knowledge of Epilepsy and Seizure-related Conditions - Medscape - Jan 12, 2016. (medscape.com)
  • Connect with other adults with epilepsy and enjoy the beautiful gardens and lake walk at Munsinger Clemens Gardens. (epilepsyfoundationmn.org)
  • Furthermore, adults with epilepsy have many social concerns (2-4), like restrictions in driving and professional constraints (5-7). (who.int)
  • A person with epilepsy is not contagious and cannot give epilepsy to another person. (cdc.gov)
  • In 2013, IBE awarded her as an 'outstanding person with epilepsy. (internationalepilepsyday.org)
  • [ 5 ] These findings reinforce the importance of understanding factors associated with ED avoidance among persons with epilepsy or seizure, the importance that all eligible persons be up to date ¶ with COVID-19 vaccination, and the need to encourage persons to seek appropriate care for seizure-related emergencies** to prevent adverse outcomes. (medscape.com)
  • SIGNIFICANCE: Some persons with epilepsy can self-predict seizures. (cdc.gov)
  • Antiepileptic drugs (AEDs) are the mainstay of treatment for epilepsy, but seizures continue in one-third of patients despite appropriate AED therapeutic trials," the authors write as background in the study. (medindia.net)
  • Ideally, treatment for epilepsy should prevent seizures before they occur. (epilepsy.org.nz)
  • Are you currently on treatment for epilepsy? (towncentresurgeryluton.nhs.uk)
  • [6] It has been described as a type of temporal lobe epilepsy . (wikipedia.org)
  • [14] Any pathophysiological changes in the M2 portion of cerebral artery which flows through lateral sulcus are associated with the epilepsies of the temporal and parietal regions. (wikipedia.org)
  • An epilepsy patient, who had not responded to any drug or surgical treatment, underwent an innovative procedure last week, which is supposed to prevent seizures caused by the disorder, for the first time in Israel. (ynetnews.com)
  • In collaboration with neurologists Dr Chris Plummer and Professor Mark Cook, neurosurgeon Associate Professor Michael Murphy and imaging specialist Simon Vogrin of Melbourne's St Vincent's Hospital, Professor David Liley of Swinburne's Brain and Psychological Sciences Research Centre is using MEG/EEG to locate and help plan surgical treatment for patients with focal epilepsy. (edu.au)
  • Psychiatric co morbidity in epilepsy, psychiatric and psychosocial morbidity before and after surgical treatment. (rcsi.com)
  • Barry, H. Psychiatric co morbidity in epilepsy, psychiatric and psychosocial morbidity before and after surgical treatment. (rcsi.com)
  • Update on surgical treatment of the epilepsies. (symptoma.com)
  • Summary of the Second International Palm Desert Conference on the Surgical Treatment of the Epilepsies» (1992). (symptoma.com)
  • The idea of using the compounds found in marijuana to treat epilepsy is gaining appeal. (healthline.com)
  • Can a Dietary Approach Help Treat Epilepsy in Adults? (sharecare.com)
  • Researchers at the University of California, San Diego School of Medicine have discovered that convulsive seizures in a form of severe epilepsy are generated, not on the brain's surface as expected, but from within the memory-forming hippocampus. (news-medical.net)
  • But the severe epilepsy that is associated with lissencephaly was never displayed in any of the previous animals, so the team kept removing gene after gene until they hit upon a strain that showed epilepsy. (news-medical.net)
  • Thinking that the deaths might be due to epilepsy, the scientists recorded electroencephalograms, which measure electrical activity produced by the firing of neurons in the brain, and found severe epilepsy in all of the mice tested. (news-medical.net)
  • A boy who had a large portion of his brain removed to relieve his severe epilepsy is still able to function normally, showing how adaptable our brains can be. (newscientist.com)
  • The US Food and Drug Administration (FDA) has cleared for marketing the Embrace smart watch (Empatica Inc) for seizure tracking and epilepsy management. (medscape.com)
  • Women's Health and Epilepsy: Are we meeting AAN Quality Measures? (umaryland.edu)
  • In many parts of the world, people with epilepsy and their families are subjected to stigmatization and discrimination as a result of the misconceptions and negative attitudes that surround epilepsy, including the belief that epilepsy is the result of possession by evil spirits or that it is contagious. (who.int)
  • Learn more about active epilepsy and find state-specific prevalence estimates on our Data and Statistics page. (cdc.gov)
  • There are almost no studies on epilepsy incidence and prevalence in Morocco. (who.int)
  • Epilepsy is a common disease with an incidence of 20-70 per 100 000 annually and prevalence of 0.5-1 % of the population. (rcsi.com)
  • Despite 20 years of ivermectin mass distribution in the Mahenge area, Tanzania , the prevalence of onchocerciasis and epilepsy has remained high in rural villages. (bvsalud.org)
  • Benign rolandic epilepsy is the most common cause of seizures in healthy school-aged children. (rush.edu)
  • Epilepsy is a brain disorder in which clusters of nerve cells (known as neurons) sometimes signal abnormally, often causing recurring seizures. (rush.edu)
  • Introduction Epilepsy is a brain disorder in which clusters of nerve cells,or neurons, in the brain sometimes signal abnormally. (myhealth.gov.my)
  • In people with focal epilepsy impairments in social cognition are under-researched. (uniklinik-freiburg.de)
  • We hope that this study will contribute to a better understanding of social cognition and the consequences of social cognitive deficits for daily living in people with focal epilepsy, and ultimately lead to the formulation of effective therapeutic strategies. (uniklinik-freiburg.de)
  • Focal epilepsy occurs when the erratic signals are confined to a specific region in the brain. (thehindu.com)
  • The RNS System is for individuals 18 and older who have focal epilepsy and have tried two or more medications without finding seizure control. (amazonaws.com)
  • Does your patient have focal epilepsy? (amazonaws.com)
  • In 2015, 1.2% of the total US population had active epilepsy. (cdc.gov)
  • According to the latest estimates, about 0.6% of children aged 0-17 years have active epilepsy. (cdc.gov)
  • a Active epilepsy is defined as adults, participating in the 2015 NHIS, who reported a history of doctor-diagnosed epilepsy or seizure disorder and either were currently taking medication to control it, or had one or more seizures in the past year, or both. (cdc.gov)
  • Zack MM, Kobau R. National and state estimates of the numbers of adults and children with active epilepsy - United States, 2015. (cdc.gov)
  • In 2015, about 3.4 million people reported having active epilepsy in the United States. (cdc.gov)
  • Russ SA, Larson K, Halfon N. A national profile of childhood epilepsy and seizure disorder. (cdc.gov)
  • Behavioral disinhibition and antiepileptic treatment in childhood epilepsy: A retrospective cohort study. (uu.nl)
  • Objective To test whether specific classes of antiepileptic drugs increase the risk for behavioral disinhibition, a frequent complication of treatment of childhood epilepsy. (uu.nl)
  • Significance This exploration of behavioral disinhibition in relation to antiepileptic drug treatment indicates that GABA potentiating drugs are specifically associated with behavioral problems during treatment of childhood epilepsy. (uu.nl)
  • Our findings may be related to the increasing evidence for a role for excitatory actions of GABA in childhood epilepsy. (uu.nl)
  • Special diets can help some children with epilepsy. (medlineplus.gov)
  • People with epilepsy often suffer from comorbidities such as depression and anxiety, associated intellectual disabilities (especially in children) and physical injuries (for instance, fractures and burns). (who.int)
  • In some settings, children with epilepsy may not be allowed to attend school, while adults with the condition may not be able to find suitable employment or to marry. (who.int)
  • Abdominal epilepsy is a rare condition most frequently found in children, consisting of gastrointestinal disturbances caused by epileptiform seizure activity . (wikipedia.org)
  • Approximately 19 months after a quality improvement project designed to reduce ED visits by children with epilepsy was implemented, a 28% reduction in ED visits and a 43% reduction in unplanned hospitalizations was demonstrated. (medpagetoday.com)
  • How do children deal with epilepsy? (clevelandclinic.org)
  • Children with an illness such as epilepsy might develop emotional problems, such as poor self-esteem, anxiety , or depression . (clevelandclinic.org)
  • Children with epilepsy might be teased by other children. (clevelandclinic.org)
  • Anxiety and depression are seen frequently in children with epilepsy sometimes even before the child has the first seizure. (clevelandclinic.org)
  • What should I know about children and epilepsy medicine? (clevelandclinic.org)
  • These children often come to the attention of specialists due to stagnation in the acquisition of language and balance skills and accompanying epilepsy. (news-medical.net)
  • Newswise - Results from a double-blind, placebo-controlled trial published in The New England Journal of Medicine revealed that children with Dravet syndrome, a severe form of epilepsy, had fewer seizures after taking a daily oral solution of the cannabis compound called cannabidiol, which does not have the psychoactive properties of marijuana. (newswise.com)
  • They work with families and schools to help children with epilepsy succeed despite their challenges. (rush.edu)
  • Child Life specialists at Rush offer children age-appropriate activities and education to help them cope with having epilepsy, while also preparing them for medical tests, procedures and surgery. (rush.edu)
  • In fact, the surge in popularity of cannabis for patients with pharmacoresistant epilepsy seems to stem from publicity surrounding MMJ for children, highlighting in particular oils made from strains with high CBD and low THC. (veterinarypracticenews.com)
  • The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. (epnet.com)
  • TECC received a grant from the Maternal Child Health Bureau at the Health Resources and Services Administration to utilize telehealth technologies to expand access to high-quality specialty and primary care for children and youth with epilepsy. (bmc.org)
  • He saw the coach speak at a gala last year and also at Camp Oz for children with epilepsy near Hudson, Wis. (twincities.com)
  • We partner with organizations like the Epilepsy Foundation of Texas Houston/Dallas/Fort Worth to create a Texas summer camp for epilepsy that recognizes the special needs of children and adults with this condition. (campforall.org)
  • Parents of teens may have specific concerns about how to manage epilepsy as their children become more independent. (cdc.gov)
  • The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care. (bvsalud.org)
  • She educates people in Mumbai on epilepsy and campaigns against the stigma attached to the disease. (internationalepilepsyday.org)
  • There, they can learn more about epilepsy, what a seizure looks like, stigma and bullying, and how to provide seizure first aid. (cdc.gov)
  • On the other hand, the Epilepsy Stigma Scale may correlate with the Rosenberg Self-esteem scale. (who.int)