Epilepsy. Medical search

A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)

A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)

A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic (i.e., occurring secondary to known disease processes such as infections, hypoxic-ischemic injuries, trauma, etc.).

Drugs used to prevent SEIZURES or reduce their severity.

A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8)

A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), and generalized major motor seizures (see EPILEPSY, TONIC-CLONIC). The myoclonic episodes tend to occur shortly after awakening. Seizures tend to be aggravated by sleep deprivation and alcohol consumption. Hereditary and sporadic forms have been identified. (From Adams et al., Principles of Neurology, 6th ed, p323)

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)

A localization-related (focal) form of epilepsy characterized by seizures which arise in the FRONTAL LOBE. A variety of clinical syndromes exist depending on the exact location of the seizure focus. Frontal lobe seizures may be idiopathic (cryptogenic) or caused by an identifiable disease process such as traumatic injuries, neoplasms, or other macroscopic or microscopic lesions of the frontal lobes (symptomatic frontal lobe seizures). (From Adams et al., Principles of Neurology, 6th ed, pp318-9)

Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.

Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder."

An autosomal dominant inherited partial epilepsy syndrome with onset between age 3 and 13 years. Seizures are characterized by PARESTHESIA and tonic or clonic activity of the lower face associated with drooling and dysarthria. In most cases, affected children are neurologically and developmentally normal. (From Epilepsia 1998 39;Suppl 4:S32-S41)

Recurrent seizures causally related to CRANIOCEREBRAL TRAUMA. Seizure onset may be immediate but is typically delayed for several days after the injury and may not occur for up to two years. The majority of seizures have a focal onset that correlates clinically with the site of brain injury. Cerebral cortex injuries caused by a penetrating foreign object (CRANIOCEREBRAL TRAUMA, PENETRATING) are more likely than closed head injuries (HEAD INJURIES, CLOSED) to be associated with epilepsy. Concussive convulsions are nonepileptic phenomena that occur immediately after head injury and are characterized by tonic and clonic movements. (From Rev Neurol 1998 Feb;26(150):256-261; Sports Med 1998 Feb;25(2):131-6)

A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.

Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their three-dimensional structure is similar.

A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.

A neurosurgical procedure that removes the anterior TEMPORAL LOBE including the medial temporal structures of CEREBRAL CORTEX; AMYGDALA; HIPPOCAMPUS; and the adjacent PARAHIPPOCAMPAL GYRUS. This procedure is generally used for the treatment of intractable temporal epilepsy (EPILEPSY, TEMPORAL LOBE).

A compound suggested to be both a nootropic and a neuroprotective agent.

A heterogeneous group of primarily familial disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intellectual deterioration, and neuronal degeneration. These include LAFORA DISEASE; MERRF SYNDROME; NEURONAL CEROID-LIPOFUSCINOSIS; sialidosis (see MUCOLIPIDOSES), and UNVERRICHT-LUNDBORG SYNDROME.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.

A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.

Surgery performed on the nervous system or its parts.

Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.

A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.

Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.

Treatment of chronic, severe and intractable psychiatric disorders by surgical removal or interruption of certain areas or pathways in the brain, especially in the prefrontal lobes.

A condition marked by recurrent seizures that occur during the first 4-6 weeks of life despite an otherwise benign neonatal course. Autosomal dominant familial and sporadic forms have been identified. Seizures generally consist of brief episodes of tonic posturing and other movements, apnea, eye deviations, and blood pressure fluctuations. These tend to remit after the 6th week of life. The risk of developing epilepsy at an older age is moderately increased in the familial form of this disorder. (Neurologia 1996 Feb;11(2):51-5)

A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.

The repeated weak excitation of brain structures, that progressively increases sensitivity to the same stimulation. Over time, this can lower the threshold required to trigger seizures.

An adjunctive treatment for PARTIAL EPILEPSY and refractory DEPRESSION that delivers electrical impulses to the brain via the VAGUS NERVE. A battery implanted under the skin supplies the energy.

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

The storing or preserving of video signals for television to be played back later via a transmitter or receiver. Recordings may be made on magnetic tape or discs (VIDEODISC RECORDING).

An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.

An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID. (From Martindale The Extra Pharmacopoeia, 31st ed)

An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)

A surgical specialty concerned with the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system.

Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools.

Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.

A disorder characterized by recurrent localized paroxysmal discharges of cerebral neurons that give rise to seizures that have motor manifestations. The majority of partial motor seizures originate in the FRONTAL LOBE (see also EPILEPSY, FRONTAL LOBE). Motor seizures may manifest as tonic or clonic movements involving the face, one limb or one side of the body. A variety of more complex patterns of movement, including abnormal posturing of extremities, may also occur.

The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.

Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.

The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.

Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.

Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)

Registered nurses who hold Master's degrees in nursing with an emphasis in clinical nursing and who function independently in coordinating plans for patient care.

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

GRAY MATTER situated above the GYRUS HIPPOCAMPI. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called GRANULE CELLS, whose AXONS pass through the polymorphic layer ending on the DENDRITES of PYRAMIDAL CELLS in the hippocampus.

(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.

A variety of neuromuscular conditions resulting from MUTATIONS in ION CHANNELS manifesting as episodes of EPILEPSY; HEADACHE DISORDERS; and DYSKINESIAS.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.

A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Dominance of one cerebral hemisphere over the other in cerebral functions.

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)

Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.

The measurement of magnetic fields over the head generated by electric currents in the brain. As in any electrical conductor, electric fields in the brain are accompanied by orthogonal magnetic fields. The measurement of these fields provides information about the localization of brain activity which is complementary to that provided by ELECTROENCEPHALOGRAPHY. Magnetoencephalography may be used alone or together with electroencephalography, for measurement of spontaneous or evoked activity, and for research or clinical purposes.

A characteristic symptom complex.

An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)

Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.

Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.

An act of employing sorcery (the use of power gained from the assistance or control of spirits), especially with malevolent intent, and the exercise of supernatural powers and alleged intercourse with the devil or a familiar. (From Webster, 3d ed)

The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.

Axons of certain cells in the DENTATE GYRUS. They project to the polymorphic layer of the dentate gyrus and to the proximal dendrites of PYRAMIDAL CELLS of the HIPPOCAMPUS. These mossy fibers should not be confused with mossy fibers that are cerebellar afferents (see NERVE FIBERS).

Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.

The largest portion of the CEREBRAL CORTEX in which the NEURONS are arranged in six layers in the mammalian brain: molecular, external granular, external pyramidal, internal granular, internal pyramidal and multiform layers.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes. (1/4971)

Otx1 and Otx2, two murine homologs of the Drosophila orthodenticle (otd) gene, show a limited amino acid sequence divergence. Their embryonic expression patterns overlap in spatial and temporal profiles with two major exceptions: until 8 days post coitum (d.p.c. ) only Otx2 is expressed in gastrulating embryos, and from 11 d.p.c. onwards only Otx1 is transcribed within the dorsal telencephalon. Otx1 null mice exhibit spontaneous epileptic seizures and multiple abnormalities affecting primarily the dorsal telencephalic cortex and components of the acoustic and visual sense organs. Otx2 null mice show heavy gastrulation abnormalities and lack the rostral neuroectoderm corresponding to the forebrain, midbrain and rostral hindbrain. In order to define whether these contrasting phenotypes reflect differences in expression pattern or coding sequence of Otx1 and Otx2 genes, we replaced Otx1 with a human Otx2 (hOtx2) full-coding cDNA. Interestingly, homozygous mutant mice (hOtx2(1)/hOtx2(1)) fully rescued epilepsy and corticogenesis abnormalities and showed a significant improvement of mesencephalon, cerebellum, eye and lachrymal gland defects. In contrast, the lateral semicircular canal of the inner ear was never recovered, strongly supporting an Otx1-specific requirement for the specification of this structure. These data indicate an extended functional homology between OTX1 and OTX2 proteins and provide evidence that, with the exception of the inner ear, in Otx1 and Otx2 null mice contrasting phenotypes stem from differences in expression patterns rather than in amino acid sequences. (+info)

Characterization of nodular neuronal heterotopia in children. (2/4971)

Neuronal heterotopia are seen in various pathologies and are associated with intractable epilepsy. We examined brain tissue from four children with subcortical or periventricular nodular heterotopia of different aetiologies: one with severe epilepsy following focal brain trauma at 17 weeks gestation, one with hemimegalencephaly and intractable epilepsy, one with focal cortical dysplasia and intractable epilepsy, and one dysmorphic term infant with associated hydrocephalus and polymicrogyria. The connectivity of nodules was investigated using histological and carbocyanine dye (DiI) tracing techniques. DiI crystal placement adjacent to heterotopic nodules revealed numerous DiI-labelled fibres within a 2-3 mm radius of the crystals. Although we observed labelled fibres closely surrounding nodules, the majority did not penetrate them. Placement of DiI crystals within nodules also identified a limited number of projections out of the nodules and in one case there was evidence for connectivity between adjacent nodules. The cellular and neurochemical composition of nodules was also examined using immunohistochemistry for calretinin and neuropeptide Y (NPY), which are normally expressed in GABAergic cortical interneurons. Within heterotopic nodules from all cases, numerous calretinin-positive neurons were identified, along with a few cell bodies and many processes positive for NPY. Calretinin-positive neurons within nodules were less morphologically complex than those in the cortex, which may reflect incomplete differentiation into an inhibitory neuronal phenotype. There were also abnormal clusters of calretinin-positive cells in the overlying cortical plate, indicating that the migratory defect which produces heterotopic nodules also affects development of the cortex itself. Thus, heterotopic nodules consisting of multiple neuronal cell types are associated with malformation in the overlying cortical plate, and have limited connectivity with other brain regions. This abnormal development of connectivity may affect neuronal maturation and consequently the balance of excitation and inhibition in neuronal circuits, leading to their epileptogenic potential. (+info)

Oligodendroglial vacuolar degeneration in the bilateral motor cortices and astrocytosis in epileptic beagle dogs. (3/4971)

We performed a pathologic examination of the brains of three dogs in an epileptic beagle colony. Histologically, all the cases had diffuse astrocytosis in the cerebral cortex and basal ganglia as well as the hippocampus, whereas they showed acute nerve cell change in the hippocampus and some other areas of the cerebrum. One of these animals showed laminar myelin pallor associated with the presence of many vacuoles in the IV to VI layers of the bilateral motor cortices. Most of the vacuoles contained fine granules stained with luxol-fast-blue stain. Ultrastructural examination revealed that some oligodendrocytes and perineuronal satellite oligodendrocytes in the bilateral cerebral motor cortices of the two affected dogs had many vacuoles surrounded by myelin-like lamellar structures. These findings suggest a possibility that astrocytosis in the cerebrum and vacuolar degeneration of oligodendrocytes in the cerebral motor cortex may be, at least in part, related to the occurrence or development of seizures. (+info)

Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic. (4/4971)

The occurrence of epileptic seizures during onchocercal infestation has been suspected. Epidemiologic studies are necessary to confirm the relation between onchocerciasis and epilepsy. A matched case-control study was conducted in dispensaries of three northwestern towns of the Central African Republic. Each epileptic case was matched against two nonepileptic controls on the six criteria of sex, age (+/-5 years), residence, treatment with ivermectin, date of last ivermectin dose, and the number of ivermectin doses. Onchocerciasis was defined as at least one microfilaria observed in iliac crest skin snip biopsy. A total of 561 subjects (187 cases and 374 controls) were included in the study. Of the epileptics, 39.6% had onchocerciasis, as did 35.8% of the controls. The mean dermal microfilarial load was 26 microfilariae per mg of skin (standard deviation, 42) in the epileptics and 24 microfilariae per mg of skin (standard deviation, 48) in the controls. This matched case-control study found some relation (odds ratio = 1.21, 95% confidence interval 0.81-1.80), although it was nonstatistically significant. (+info)

Adjunctive therapy in epilepsy: a cost-effectiveness comparison of two AEDs. (5/4971)

The objective of this study was to compare the relative cost-effectiveness of two AEDs by a prospective clinical audit. Patients starting on the adjunctive therapies lamotrigine and topiramate were recruited from the out-patient epilepsy clinics at Queen Square. Three interview were scheduled: baseline; three months follow-up and six months from baseline. Of the 81 patients recruited, a total of 73 patients completed all three interviews. An intention to treat analysis was performed on the data. Seizure severity and frequency were assessed using the National Hospital Seizure Severity Scale. Side-effects, adverse events and reasons for stopping medication were also recorded. At the third interview, a total of 47/73 (64%) were still on the prescribed adjunctive drug. Outcome was assessed by two methods: the > 50% seizure reduction cited in the literature and a more stringent assessment of patient 'satisfaction' which we defined operationally on clinical criteria. Using this definition, a total of 10/73 (14%) patients were 'satisfied'. The relative costs of starting patients on each of the two AEDs were calculated, both drug costs and the costs of adverse events (the latter were defined as events requiring urgent medical attention). The costs of the two drugs were compared. A number of methodological issues relating to cost comparison are discussed. Outcome and pharmaco-economic studies need to assess more than reduction in number of seizures. They should take into account variables important for quality of life including side-effects and adverse events. (+info)

Willingness to pay: a feasible method for assessing treatment benefits in epilepsy? (6/4971)

Contingent valuation using willingness to pay (WTP) is one of the methods available for assessing the value of a new technology or treatment for a disease in monetary terms. Experience with this method is lacking in epilepsy. The objectives of this study were to assess the acceptability of the WTP method in epilepsy, the level of the responses, and to investigate its validity by comparison with other non-monetary preference measures. Among 397 patients with epilepsy responding to a comprehensive questionnaire, 82 were randomly selected for an interview. They were asked about their WTP for an imaginary new technology which could permanently cure their epilepsy. Fifty-nine patients participated and 57 completed the interview (32 women; mean age 44 years), the majority with well-controlled epilepsy. The patients indicated a median WTP of Norwegian Kroner (NOK) 150,000 (USD 20,000; GBP 11,800), interquartile range NOK 50,000-350,000 (USD 6, 667-46, 667; GBP 3,937-27,559) for this cure. Non-response was low, indicating high acceptability of this method. There was little association between WTP and other preference measures; the Spearman rank correlation coefficient was -0.09 and -0.12 with time trade-off and standard gamble respectively, questioning the validity of this method. (+info)

Outcome of pregnancies in epileptic women: a study in Saudi Arabia. (7/4971)

We studied the outcome of 79 pregnancies in 44 Saudi women who had epilepsy. Their mean age was 28+/-6.5 years and the number of pregnancies studied varied from one to six. Nineteen subjects had generalized seizures, 16 had partial seizures and nine were unclassified. The commonest drug prescribed was carbamazepine and the majority of the women (61%) were on monotherapy. The seizures were controlled in 53 pregnancies (67%). Spontaneous vertex deliveries were the commonest. The indications for intervention by lower segment Caesarean section, forceps or ventouse were foetal distress, pre-eclamptic toxaemia (PET), eclampsia, breech presentation and prolonged labour. The most frequent adverse outcome in the babies was low birth weight (<2.5 kg) in nine pregnancies. The frequency of congenital malformation was 2.5%. Low birth weight was associated with prematurity, PET, congenital malformation and polytherapy. Avoidance of polytherapy appears to be the most feasible intervention in reducing the frequency of low birth-weight children by epileptic mothers. (+info)

Information exchange in an epilepsy forum on the World Wide Web. (8/4971)

The Partners Healthcare Epilepsy Service hosts an epilepsy 'Webforum'. In this paper, we describe our observations regarding who uses it, what kind of information is exchanged, how much misinformation is present and how we can better serve our patients. We examined a sample of 155 posts to the forum and 342 responses to those posts. The individual making the post and the type of questions were categorized. We also determined whether any information was objectively inaccurate. The principal users were care-givers (49%) and patients (34%). Eighty percent of the primary posts were questions. Answers were given largely by patients (38%) and care-givers (34%). The most commonly asked questions were about treatment options (31%) and the natural history of the illness (28%). In 20% of the questions, the user incidentally remarked that a health-care provider had not met their information needs. Six percent of the information was objectively inaccurate. The Web can serve as an effective means for the exchange of information between individuals with a common medical condition. We found that a small amount of misinformation is exchanged and that health-care providers are sometimes perceived as unable or unwilling to supply important health-related information. (+info)

It is not yet clear, however, whether the epilepsy is usually caused by hippocampal abnormalities or whether the hippocampus is ... Seizures in temporal lobe epilepsy can affect the normal development of new neurons and can cause tissue damage. Hippocampal ... Kuruba R, Hattiangady B, Shetty AK (Jan 2009). "Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy". ... Damage to the hippocampus can also result from oxygen starvation (hypoxia), encephalitis, or medial temporal lobe epilepsy. ...

https://en.wikipedia.org/wiki/Hippocampus

... epilepsy; floods; fruit dealers; fullers; gardeners; a holy death; mariners; market carriers; motorists and drivers; sailors; ...

https://en.wikipedia.org/wiki/Saint_Christopher

... epilepsy; fetal alcohol syndrome disorders (FASD); generalized anxiety disorder; hearing impairment; hydrocephalus; limb ...

https://en.wikipedia.org/wiki/Kupenda_for_the_Children

"Epilepsy". Mchb.hrsa.gov. Archived from the original on 2014-01-01. Retrieved 2013-12-31. "Early Childhood Programs". Mchb.hrsa ... Autism and Epilepsy Grants to improve health care and other services for children and adolescents with autism spectrum ...

https://en.wikipedia.org/wiki/Maternal_and_Child_Health_Bureau

July 2012). "Validation of the Subjective Handicap of Epilepsy (SHE) in Brazilian patients with epilepsy". Epilepsy & Behavior ... Epilepsy. The Epilepsy Surgery Inventory 55 (ESI-55) was developed at the University of California and covers eleven health ... Selai CE, Elstner K, Trimble MR (January 2000). "Quality of life pre and post epilepsy surgery". Epilepsy Research. 38 (1): 67- ... Vickrey BG (1993). "A procedure for developing a quality-of-life measure for epilepsy surgery patients". Epilepsia. 34 Suppl 4 ...

https://en.wikipedia.org/wiki/List_of_patient-reported_quality_of_life_surveys

His PhD thesis was on the stigma experienced by adults with epilepsy living in the community. He was appointed Lecturer in ... London: Tavistock Scambler, G. (1989). Epilepsy. London: Tavistock Scambler, A. & Scambler, G. (1993). Menstrual disorders. ...

https://en.wikipedia.org/wiki/Graham_Scambler

"Epilepsy". Facebook.com. Retrieved 22 May 2019. "The wonderwoman against epilepsy". Zimbanice.co.zw. Retrieved 22 May 2019. " ... So they need to speak out and share what they go through from what they know," said Lipsy Epilepsy is a chronic disorder of ... A person is diagnosed with epilepsy if they have two unprovoked seizures (or one unprovoked seizure with the likelihood of more ... she told of how society had shunned her and how she had lost friends because of the epilepsy. and it has impacted on her career ...

https://en.wikipedia.org/wiki/Ninja_Lipsy

... definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)". ... In epilepsy, seizures have a tendency to recur and, as a rule, have no immediate underlying cause. Isolated seizures that are ... "Epilepsy Fact sheet". WHO. February 2016. Archivedfrom the original on 11 March 2016. Retrieved 4 March 2016. Fisher R, van ... Epilepsy - is a group of neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures are episodes ...

https://en.wikipedia.org/wiki/Glossary_of_medicine

Seizure: European Journal of Epilepsy is a peer-reviewed medical journal covering epilepsy established in 1992. The editor-in- ... Official website Epilepsy Action (Articles with short description, Short description matches Wikidata, 10 times per year ... "Epilepsy". NLM Catalog. National Center for Biotechnology Information. PsycINFO Journal Coverage, American Psychological ... chief is Markus Reuber (University of Sheffield). It is the official journal of Epilepsy Action. It is published ten times a ...

https://en.wikipedia.org/wiki/Seizure_(journal)

Coppola, Antonietta; Moshé, Solomon L. (2012). "Animal models". Epilepsy. Handbook of Clinical Neurology. Vol. 107. pp. 63-98. ...

https://en.wikipedia.org/wiki/TMEM211

Rogawski M (1996). "Epilepsy". In Pullan L, Patel J (eds.). Neurotherapeutics: Emerging Strategies. Humana Press. pp. 193-273. ... In addition, at low, nontoxic doses, the drug has anti-absence activity in a genetic model of generalized absence epilepsy. ...

https://en.wikipedia.org/wiki/Loreclezole

"Epilepsy". www.ukdmc.org. UK diving medical committee. Retrieved 31 December 2019. "Can I dive with Epilepsy?". DDRC healthcare ... Epilepsy is a central nervous system disorder in which the person has had at least two seizures, often for no discernible cause ... If epilepsy is required to be controlled by medication, diving is contraindicated. A possible acceptable risk would be a ... Even if no one with a history of epilepsy dived, a few people would experience their first seizure while diving. As a seizure ...

https://en.wikipedia.org/wiki/Fitness_to_dive

The exact causes of epilepsy are not fully known or understood, but it is thought to be caused by a chemical imbalance in the ... Because, however, the cause of epilepsy is centred in the brain, there was doubt for some time as to whether or not it should ... A case in which a defence relying on epilepsy succeeded is R v Mkize. Mkize was an epileptic. One day, while cutting meat with ... The court accepted that the nature of his epilepsy was such that he would not normally have realised or foreseen the dangers of ...

https://en.wikipedia.org/wiki/South_African_criminal_law

... epilepsy; movement disorders such as Parkinson's disease; headache and concussion treatment; trauma; injuries; and more. Norton ...

https://en.wikipedia.org/wiki/Norton_Healthcare

... epilepsy. May impair ability to drive or operate machinery. CNS depression including slight drowsiness to deep sleep, lassitude ...

https://en.wikipedia.org/wiki/Mequitazine

"Seizure First Aid , Epilepsy , CDC". www.cdc.gov. 2020-09-30. Retrieved 2021-12-08. Pavitt MJ, Swanton LL, Hind M, et al. (12 ... Seizing can occur for a multitude of reasons but is common in those diagnosed with epilepsy. During a seizure, victims may ... people with epilepsy, and people on the autism spectrum. They may require more assistance to feed themselves, and it may be ...

https://en.wikipedia.org/wiki/Choking

Risks were listed as death due to cerebral haemorrhage or infection; epilepsy; and personality changes. A text book of the day ...

https://en.wikipedia.org/wiki/History_of_psychosurgery_in_the_United_Kingdom

... epilepsy; learning problems; cognitive disabilities - mild to moderate; developmental delay - mild to moderate (milestones like ...

https://en.wikipedia.org/wiki/1q21.1_deletion_syndrome

... epilepsy; acute or chronic glaucoma; and some forms of intractable pain." The initiative also allowed the state to add new ...

https://en.wikipedia.org/wiki/Cannabis_in_Washington_(state)

"Epilepsy". Online Etymology Dictionary. "Nymphai". Theoi Project. "Thera". World History Encyclopedia. "Santorini to the Cave ... ", "beautiful young woman", then "semi-divine being in the form of a beautiful maiden", and epilepsy, from the Greek word ...

https://en.wikipedia.org/wiki/Nympholepsy

Another common cause is epilepsy. According to Medlineplus epilepsy can be described as a brain disorder that causes seizures ( ... for the Study of Epilepsy and the care and treatment of Epileptics, 22 Nov 1904: 'That is to say the psyche may take on an ... "Epilepsy". Retrieved 5 December 2013. Revonsuo, Antti; Kallio, Sakari; Sikka, Pilleriin (April 2009). "What is an altered state ... as it was in relation to epilepsy, and is still used today. In academia, the expression was used as early as 1966 by Arnold M. ...

https://en.wikipedia.org/wiki/Altered_state_of_consciousness

Epilepsy; "Lemons"; Inventors' Fair; Cuttlefish (December 2, 1989) DNA; Rube Goldberg Contest; Parrot Chat; Chewing Tin Foil; ...

https://en.wikipedia.org/wiki/Newton's_Apple

Epilepsy Research. 46 (3): 241-250. doi:10.1016/S0920-1211(01)00280-7. ISSN 0920-1211. PMID 11518625. Kryger (2017). Principles ...

https://en.wikipedia.org/wiki/Cyclic_alternating_pattern

Moshé, editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. (2006). Models of seizures and epilepsy. Amsterdam: Elsevier ... Epilepsy Research. 23 (3): 189-194. doi:10.1016/0920-1211(95)00094-1. PMID 8739122. S2CID 21818415. Hradetzky, Eva; et al. (28 ... video-EEG monitoring has documented the presence of spontaneous electrographic seizure activity In some epilepsy rat models, ... which reduces DNA synthesis used in making animal models of neurological diseases including schizophrenia and epilepsy. MAM is ...

https://en.wikipedia.org/wiki/Methylazoxymethanol_acetate

Stafstrom CE (2007). "Persistent Sodium Current and Its Role in Epilepsy". Epilepsy Currents. 7 (1): 15-22. doi:10.1111/j.1535- ...

https://en.wikipedia.org/wiki/Pre-Bötzinger_complex

Hart EJ (May 1990). "Nintendo epilepsy". The New England Journal of Medicine. 322 (20): 1473. doi:10.1056/NEJM199005173222020. ...

https://en.wikipedia.org/wiki/Nintendo_thumb

Hystero-epilepsy is a historical term that refers to a condition described by 19th-century French neurologist Jean-Martin ... The most definitive test to distinguish epilepsy from PNES is long term video-EEG monitoring, with the aim of capturing one or ... Features that are common in PNES but rarer in epilepsy include: biting the tip of the tongue, seizures lasting more than two ... 19 (3 Epilepsy): 715-29. doi:10.1212/01.CON.0000431399.69594.de. PMID 23739106. S2CID 30032816. LaFrance WC, Baker GA, Duncan R ...

https://en.wikipedia.org/wiki/Psychogenic_non-epileptic_seizure

... but has been shown that meningitis can cause epilepsy, which would give rise to the possibility of developing epilepsy ... Epilepsy most often occurs at the extremes of life - in childhood or in very old age - but can develop at any time throughout ... These infections are most likely to result in epilepsy when they occur at an early age. Problems with brain development can ... If a seizure happens during the infection itself, the person most likely doesn't have epilepsy but has "symptomatic seizures" ...

https://en.wikipedia.org/wiki/Epilepsia_partialis_continua

Epilepsy Res. 34 (2-3): 177-86. Sheehan, JJ; Benedetti, BL; Barth, AL (2009). "Anticonvulsant effects of the BK-channel ...

https://en.wikipedia.org/wiki/Paxilline

Garga N, Lowenstein DH (2006). "Posttraumatic epilepsy: A major problem in desperate need of major advances". Epilepsy Curr. 6 ... Pitkänen A, McIntosh TK (2006). "Animal models of post-traumatic epilepsy". Journal of Neurotrauma. 23 (2): 241-261. doi: ...

https://en.wikipedia.org/wiki/Primary_and_secondary_brain_injury

... such as how many people have epilepsy and the annual cost of epilepsy. ... Learn basic information about epilepsy in the United States, ... Who Has Epilepsy?. Active Epilepsya. In 2015, 1.2% of the total ... What Is Epilepsy?. Epilepsy is a disorder of the brain that causes seizures. These seizures are not caused by a temporary ... a Active epilepsy is defined as adults, participating in the 2015 NHIS, who reported a history of doctor-diagnosed epilepsy or ...

https://www.cdc.gov/epilepsy/about/fast-facts.htm

The FDA has cleared the first smart watch for seizure tracking and epilepsy management. The device uses advanced machine ... Embrace was tested in a clinical study involving 135 patients with epilepsy who were admitted to epilepsy monitoring units for ... Minorities With Epilepsy Blocked From Receiving Highest Quality of Care * Modified Atkins Diet Beneficial in Drug-Resistant ... "The FDA approval of the Embrace device to detect major convulsive seizures represents a major milestone in the care of epilepsy ...

https://www.medscape.com/viewarticle/892329

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, ... Epilepsy and Pregnancy (American Academy of Family Physicians) Also in Spanish * Epilepsy and Pregnancy: What You Need to Know ... Epilepsy - children (Medical Encyclopedia) Also in Spanish * Epilepsy - children - discharge (Medical Encyclopedia) Also in ... Epilepsy Data and Statistics (Centers for Disease Control and Prevention) * Epilepsy Fast Facts (Centers for Disease Control ...

https://medlineplus.gov/epilepsy.html

The exact prevalence of autoimmune causes of epilepsy is not known. According to Dr Britton, a few studies have suggested that ... Dr Carreños own study of 13 patients with drug-resistant epilepsy due to autoimmune encephalitis showed that surgery may be a ... "Over the past few years, there has been increasing recognition that some forms of epilepsy are immune mediated; theyre ... At a press briefing during the American Epilepsy Society (AES) 69th Annual Meeting here, Dr Steriade presented a study ...

http://www.medscape.com/viewarticle/855551

Epilepsy. Temporal lobe epilepsy. Frontal lobe epilepsy. Rolandic epilepsy. Sleep-related hypermotor epilepsy. Panayiotopoulos ... "Abdominal Epilepsy in Children and Adults". Epilepsy Health Center. WebMD. 18 March 2013. Retrieved 13 February 2014.. ... Autonomic epilepsy. Abdominal epilepsy is a rare condition most frequently found in children, consisting of gastrointestinal ... Like other forms of epilepsy, abdominal epilepsy is treated with anticonvulsant drugs, such as phenytoin. Based on the clinical ...

https://en.wikipedia.org/wiki/Abdominal_epilepsy

249 Crumlin Rd, Dublin 12, D12RW92, Ireland , Tel +353 1 455 7500 , [email protected]epilepsy.ie , © Epilepsy Ireland , Registered Charity ... Questions or concerns about epilepsy?. Contact us on +353 1 455 7500 or [email protected]epilepsy.ie. ... From an Epilepsy Ireland perspective, using the funds raised, we hope to extend SUDEP Actions renowned SUDEP and Seizure ... Their extraordinary efforts aim to raise funds for both Epilepsy Ireland and our colleagues in SUDEP Action. Although the cycle ...

https://www.epilepsy.ie/content/cycle-shane

In approximately 1/3 of patients with epilepsy, seizures persist despite adequate trials of several antiepileptic drugs (AEDs ... juvenile absence epilepsy, juvenile myoclonic epilepsy, generalized epilepsy and febrile seizures plus, and various progressive ... frontal lobe epilepsies (several locations), parietal lobe epilepsies, occipital lobe epilepsies, and Rasmussen encephalitis ... Anesthesia in Epilepsy Surgery. Engel J Jr, ed. Surgical Treatment of the Epilepsies. 2nd ed. New York, NY: Raven Press; 1993. ...

https://emedicine.medscape.com/article/251449-overview

Epilepsy Employment Group (EEG) is a Job Search Support Group. Join in and meet some new people, swap points of view and learn ... Epilepsy Employment Group (EEG) is a Job Search Support Group for people living with epilepsy. This group is meeting online via ... Epilepsy Toronto offers services on the traditional territory of many nations including the Mississaugas of the Credit, the ... For more infomation or to rsvp for the next Epilepsy Employment Group, contact Carter at [email protected] and well ...

https://epilepsytoronto.org/event/eeg-epilepsy-employment-group-2-4-2-4-2/

Science News was founded in 1921 as an independent, nonprofit source of accurate information on the latest news of science, medicine and technology. Today, our mission remains the same: to empower people to evaluate the news and the world around them. It is published by the Society for Science, a nonprofit 501(c)(3) membership organization dedicated to public engagement in scientific research and education (EIN 53-0196483).. ...

https://www.sciencenews.org/archive/launch-epilepsy-attack

Drivers With Epilepsy: Balancing Quality of Life and Public Safety Guidelines issued by professional societies and advocacy ... Paul Gringras, MD, on the Two-way Street of Epilepsy and Sleep This expert discusses the common, often highly disruptive ... Accidental Death and Suicide in Patients with Epilepsy: Scope of the Problem A new study advances our knowledge about the ... Ask the Expert: Andres M. Kanner, MD on Psychiatric Comorbidities in Patients with Epilepsy Andres Kanner, MD, shares ways to ...

https://www.medpagetoday.com/resource-centers/focus-on-epilepsy/clinical-essentials

Some people who suffer from epilepsy believe that marijuana stops their seizures. Two compounds found in the drug, THC and CBD ... Facts about seizures and epilepsy (2013).. epilepsy.com/learn/epilepsy-101/facts-about-seizures-and-epilepsy. ... Epilepsy is a nervous system disorder that causes seizures. Absence seizures, also called petit mal seizures, are brief and may ... Many people with epilepsy can manage their seizures with proper medications and treatment. Get facts about the long-term ...

https://www.healthline.com/health/marijuana-and-epilepsy

... is a medical condition that occurs when a person has recurring seizures. It is also called a ... There is research to suggest that one or more genes may cause epilepsy. Other causes of epilepsy may include:. *Infections of ... The exact cause of epilepsy varies. In some people, there is no clear cause of epilepsy. ... What is Epilepsy? Seizures are caused by sudden, abnormal activity in the brain. In many cases, seizures are just a onetime ...

https://intermountainhealthcare.org/services/neurosciences/conditions/epilepsy/

The misdiagnosis of epilepsy The rate of misdiagnosis and wide treatment choices are arguments for specialist care of epilepsy ... The misdiagnosis of epilepsy. BMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7336.495 (Published 02 March 2002) Cite this ...

https://www.bmj.com/content/324/7336/495/article-info

That was over a year ago, and since then my family has been living with epilepsy. I know now that what she had was called a ... Canine epilepsy is common in certain breeds, particularly collies and poodles. While there is no cure, it is definitely a ... Belles on medication now, phenobarbitol (the most common med given to dogs with epilepsy). She is still having seizures, ...

https://everything2.com/title/canine+epilepsy

Our Comprehensive Epilepsy Genetics Program can help us diagnose and treat patients with epilepsy who have a family history or ... Resources from our Epilepsy Education Series . *Canada Revenue Agency (CRA) Benefits. *Canada Pension Plan - Useful Resources ... Epilepsy is a disease where there is still a lot of misunderstanding. At the Krembil Brain Institute, we know about the ... Epilepsy Pregnancy Clinic. Treatments. Multiple treatment options are available at the Krembil Brain Institute. In addition to ...

https://www.uhn.ca/Krembil/Clinics/Epilepsy_Clinic

Anyone can get epilepsy at any point in their life. Over 1 % of Finns with epilepsy are over 65-year-old, which is more than ... For some, epilepsy has been present since childhood. Some get ill at an older age. The reasons for epilepsy can be common ... An open attitude to epilepsy reduces prejudice and makes it easier to cope. Others who live with epilepsy can give different ... You can find more detailed information in Finnish on the Terveyskylä.fi -website about epilepsy and epilepsy in older adults. ...

https://www.epilepsia.fi/en/about-epilepsy/adults/older-adults/

Estimate of annual incidence of epilepsy are as high as 43 cases per 100,000 of the population in so-called developed countries ... The cumulative lifetime risks for epilepsy and for any unprovoked seizure are 3.1% and 4.1%, respectively, in industrialized ... Epilepsy is a common disease. The cumulative lifetime risks for epilepsy and for any unprovoked seizure are 3.1% and 4.1%, ... Within this there is a growing appreciation of gender differences in the epidemiology of epilepsy and of specific epilepsy ...

https://pubmed.ncbi.nlm.nih.gov/18929074/?dopt=Abstract

Help Becca Garner raise money to support Epilepsy Action ...

https://www.justgiving.com/fundraising/becca-gledhill85

Frontal lobe epilepsy is characterized by recurrent seizures arising from the frontal lobes. Frequently, seizure types are ... Outcome of frontal lobe epilepsy surgery in adults. Epilepsy Res. 2008 Oct. 81 (2-3):97-106. [QxMD MEDLINE Link]. ... Brodtkorb E, Picard F. Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy. Epilepsy Behav. 2006 Nov. 9( ... encoded search term (Frontal Lobe Epilepsy) and Frontal Lobe Epilepsy What to Read Next on Medscape ...

https://emedicine.medscape.com/article/1184076-differential

Understanding Epilepsy Main Menu * What is Epilepsy? * Understanding Seizures * Who Can Get Epilepsy?. ... Living With Epilepsy Main Menu * Tracking & Managing Seizures * Managing Triggers * How to Indentify Seizure Triggers. ... ️ 2022 Epilepsy Foundation®️, is a non-profit organization with a 501(c)(3) tax-exempt status. Tax ID: 52-0856660 ... Please join Camila, Cynthia and many, many more in this brave act of standing up against epilepsy. The eJourney is yours, and ...

https://www.epilepsy.com/stories/ejourney?f%5B0%5D=audience%3A33246&f%5B1%5D=modes%3A34906&f%5B2%5D=type_of_epilepsy_or_syndrome%3A34701

... including how to help a child deal with epilepsy and tips for medicine. ... Find information and more about epilepsy in children from Cleveland Clinic, ... Epilepsy in Children This article details common concerns facing a parent who has a child with epilepsy, and how to handle them ... Children with epilepsy might be teased by other children.) Anxiety and depression are seen frequently in children with epilepsy ...

https://my.clevelandclinic.org/health/treatments/12252-epilepsy-in-children

2019)‎. Epilepsy and seizures. World Health Organization. Regional Office for the Eastern Mediterranean. https://extranet.who. ...

https://extranet.who.int/iris/restricted/handle/10665/333483?locale-attribute=de&

... epilepsy - Sharing our stories on preparing for and responding to public health events ... Tags epilepsy, preparedness Loving Someone With Epilepsy. When Zayan first told me that he has epilepsy, I didnt believe him ... Epilepsy and Emergency Preparedness. November is National Epilepsy Awareness Month Epilepsy is common. In 2015, about 3.4 ... Epilepsy is a broad term used for a brain disorder that causes repeated seizures. There are many different types of epilepsy. A ...

https://blogs.cdc.gov/publichealthmatters/tag/epilepsy/

Examine the company profile of Epilepsy Foundation New England and learn about Epilepsy Foundation New England jobs and career ...

https://www.military.com/jobsearch/browse/search/Epilepsy-Foundation-New-England_6

Epilepsy, grand mal: Epilepsy that includes tonic-clonic (grand mal) seizures, which are the most obvious type of seizure. ... What Is Epilepsy? Symptoms, Causes, and Treatments See Slideshow From Brain & Nervous Resources. *11 Tips for Avoiding Seizure ... Read medical definition of Epilepsy, grand mal ... Definition of Epilepsy, grand mal. *Medical Editor: Melissa ...

https://www.rxlist.com/epilepsy_grand_mal/definition.htm

... Dispelling the Top 5 Epilepsy Myths Although much is still unknown about epilepsy, experts agree that these ... Nutrition Epilepsy Erectile Dysfunction Fitness & Exercise Flu Treatment Healthy Aging & Retirement Heart Health Heartburn & ...

https://www.qualityhealth.com/epilepsy-index/causes

Find out everything you need to know about epilepsy including symptoms, treatment, causes, management and more. ... Health Topicsbrain-health-nervous-systemEpilepsy. Epilepsy. Find out everything you need to know about epilepsy including ... What Is Epilepsy?. Epilepsy is a nervous system disorder and there are three different types of it. In this video, fami.... ... What Causes Epilepsy?. A few different things can cause epilepsy including genetics and infections. In this video, family p... ...

https://www.sharecare.com/brain-health-nervous-system/epilepsy

Children dont always understand the potential perceptions and implications of their actions, Center Grove officials said in a letter to parents.

https://www.indystar.com/story/news/2018/12/04/james-franklin-jr-center-grove-high-officials-epilepsy-controversy-cathedral-high-basketball/2200133002/

Sudden unexpected deaths in epilepsy have proven difficult to unravel. A recent study concludes that they might be driven by ... What to know about epilepsy. Medically reviewed by Heidi Moawad, MD. Epilepsy is a fairly common neurological condition ... Uncontrolled epilepsy is the primary risk factor for sudden unexpected death in epilepsy (SUDEP). ... their findings in the journal Epilepsy Research.. The team was headed up by Prof. Pedro Irazoqui who was inspired by his own ...

https://www.medicalnewstoday.com/articles/324157

The International League Against Epilepsy has updated its classification of seizure types in large part to clarify terminology, categorize certain seizure types as either focal or generalized, and classify seizures when the onset is unknown. (medpagetoday.com)
In 1993, the International League Against Epilepsy (ILAE) proposed simplified classification guidelines to facilitate epidemiologic work in epilepsy, and to allow meaningful comparison between studies undertaken at different times and in different parts of the world. (nih.gov)
In this review, the development of the current classification of epilepsy syndromes will be discussed, followed by the recent efforts of the International League Against Epilepsy Commission on Classification and Terminology to address necessary changes in diagnostic categories and the conceptual framework that gives rise to these groupings. (semanticscholar.org)
The International League Against Epilepsy presents a revised operational classification of seizure types to recognize that some seizure types can have either a focal or generalized onset, to allow classification when the onset is unobserved, to include some missing seizure types, and to adopt more transparent names. (semanticscholar.org)
An International League Against Epilepsy task force has evaluated the need for revising the current classification and terminology and has begun developing four specific documents, including a classification of epileptic seizures based on known or presumed pathophysiological and anatomic substrates. (semanticscholar.org)
In 2014, the International League Against Epilepsy Epilepsy Guidelines Task Force expanded the practical definition of epilepsy to include having at least two unprovoked seizures more than 24 hours apart, having one unprovoked seizure and a probability of further seizures of at least 60%, and a diagnosis of an epilepsy syndrome. (medscape.com)
These data are part of a systematic review from the Mortality Task Force of the International League Against Epilepsy from 2017. (mentalhealthandmedicine.org)
The burden of premature mortality of epilepsy in high-income countries: A systematic review from the Mortality Task Force of the International League Against Epilepsy. (mentalhealthandmedicine.org)
[ 6 ] and has been adopted by the International League Against Epilepsy (ILAE). (medscape.com)

Tragically, more than 3000 Americans die each year from sudden unexpected death in epilepsy (SUDEP) and the Embrace offers the potential to alarm family members and caretakers that a tonic-clonic seizure is occurring. (medscape.com)
The Cycle for Shane was set up in memory of the late Shane Corrigan - who sadly passed away from Sudden Unexpected Death in Epilepsy (SUDEP) in January 2018. (epilepsy.ie)
The American Academy of Neurology and the American Epilepsy Society created new evidence-based practice guidelines on sudden unexpected death in epilepsy. (medpagetoday.com)
These include the incidence of status epilepticus (more common in men), incidence of sudden unexpected death in epilepsy (SUDEP), prognosis, and mortality. (nih.gov)
Could acid reflux explain sudden unexpected death in epilepsy? (medicalnewstoday.com)
Uncontrolled epilepsy is the primary risk factor for sudden unexpected death in epilepsy (SUDEP). (medicalnewstoday.com)

This is very unique and not seen in other types of epilepsy. (medscape.com)
There are many different types of epilepsy. (cdc.gov)
Parents of children with epilepsy, especially the most severe types of epilepsy, are desperate for a deeper understanding of the causes of the problems and for the development of new treatments. (news-medical.net)
It revealed which of the many types of epilepsy had a genetic basis, and which didn't, so as to better target their gene discovery studies. (futurity.org)
This paper explores how the indications of the diet changed together with the shifting focus of epilepsy teams towards its use in different types of epilepsy and epilepsy syndromes and according to etiologies and as an alternative option in refractory and superrefractory status epilepticus . (bvsalud.org)

(https://www.who.int/mental_health/neurology/epilepsy/report_2019/en/, accessed 12 October 2019). (who.int)
Patients with autoimmune epilepsy may benefit from early-initiated immunotherapy, shows study published in Archives of Neurology. (medindia.net)
To evaluate clinical characteristics and immunotherapy responses in patients with autoimmune epilepsy, Amy M. L. Quek, M.B.B.S., of the Mayo Clinic, College of Medicine, Rochester, Minn., and colleagues, gathered data from the Mayo Clinic computerized diagnostic index from patients who were evaluated in both the Autoimmune Neurology Clinic and Epilepsy Clinic between January 2005 and December 2010, and were diagnosed with autoimmune epilepsy. (medindia.net)
The patient had not responded to any surgical or other treatment and had run out of options,' Director of Epilepsy and EEG Service and Deputy Director of the Neurology Department in Sheba Prof. Nicola Maggio said. (ynetnews.com)
All patients diagnosed with epilepsy through BMC's pediatric neurology department will be given the choice of creating a virtual care plan via the platform go.ACT.md . (bmc.org)
All patients admitted to the Epilepsy Monitoring Unit or who attended the Neurology OPD in Beaumont Hospital with treatment resistant epilepsy are considered a candidate for inclusion. (rcsi.com)
Today, I have the pleasure of speaking with Dr Jacqueline French, professor of neurology and epileptologist at NYU Comprehensive Epilepsy Center. (medscape.com)

Within this there is a growing appreciation of gender differences in the epidemiology of epilepsy and of specific epilepsy syndromes. (nih.gov)
Also, the behavior of some common epilepsy syndromes such as mesial temporal sclerosis may differ between genders with isolated auras more common among females and secondary seizure spread more likely in males. (nih.gov)
The role of EEG in the diagnosis and classification of the epilepsy syndromes: a tool for clinical practice by the ILAE Neurophysiology Task Force (Part 1). (medscape.com)
The present review discusses the issues related to several of these epilepsy syndromes in childhood, including Dravet's Syndrome, West Syndrome, Lennox-Gastaut Syndrome, Myoclonic Astatic Epilepsy, and Landau-Kleffner Syndrome. (semanticscholar.org)
Many different conditions or syndromes can cause epilepsy. (phoenixchildrens.org)
Juvenile myoclonic epilepsy (JME) is one of the most common idiopathic (genetic) generalized epilepsy (IGE) syndromes. (medscape.com)
It is important to view IGE as a spectrum of genetic epilepsies with individual syndromes (such as JME) but with significant overlap. (medscape.com)
In the "ILAE Definition of the Idiopathic Generalized Epilepsy Syndromes: Position Statement by the ILAE Task Force on Nosology and Definitions," JME is defined as "the most common adolescent and adult onset IGE syndrome and is characterized by myoclonic and generalized tonic-clonic seizures in an otherwise normal adolescent or adult. (medscape.com)
When idiopathic partial epilepsy syndromes were excluded, the 5 pairs accounted for 23% of monozygotic pairs with partial epilepsies, and 38% of monozygotic pairs with partial epilepsy and no known etiology . (symptoma.com)

2019)‎. Epilepsy and seizures. (who.int)

From an Epilepsy Ireland perspective, using the funds raised, we hope to extend SUDEP Action's renowned SUDEP and Seizure Safety Checklist to Ireland. (epilepsy.ie)
This resource has widely been integrated into the care of people with epilepsy in the UK to help clinicians discuss SUDEP risk and to make people with epilepsy and their families more aware about SUDEP. (epilepsy.ie)
SUDEP affects an estimated 1 in 1,000 adults with epilepsy each year. (medicalnewstoday.com)

To address the challenges and gaps in providing care for people with epilepsy and other neurological disorders, the Seventy-fifth World Health Assembly (WHA) in May 2022 adopted the Intersectoral global action plan on epilepsy and other neurological disorders (IGAP), which aims to improve access to care and treatment for people living with neurological disorders while preventing new cases and promoting brain health and development across the life course. (who.int)
While marking the Epilepsy awareness challenge 2022, Fatima shared a mirror picture wearing a fuzzy trench coat, on her social media, while writing down a caption about Epilepsy that appeals to the mass audience as she also urged people to share their stories of epilepsy. (thestatesman.com)
I'm Dr Andrew Wilner, reporting virtually from the 2022 American Epilepsy Society meeting in Nashville, Tennessee. (medscape.com)

Mixed mood and anxiety disorders in conjunction with a genetic psychiatric history have been identified as factors of poorer seizure control in patients with mesial temporal lobe epilepsy. (medpagetoday.com)
Andres Kanner, MD, shares ways to expedite the diagnosis and management of mood and anxiety disorders among patients with epilepsy within the time constraints of a busy medical practice. (medpagetoday.com)
2014). Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. (healthline.com)
The reasons for epilepsy can be common disorders in the brain, such as cerebrovascular diseases, brain tumors and degenerative diseases of the brain. (epilepsia.fi)
Genetic epilepsy refers to a number of seizure disorders (e.g. (rush.edu)
Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Epilepsy-Information-Page. (epnet.com)
As a result, WHO and other partners have been engaging stakeholders to share ideas towards the effective implementation of the Intersectoral global action plan on epilepsy and neurological disorders in Ghana. (who.int)
There is the need for collaboration between relevant stakeholders - everyone in healthcare at all levels, social care, advocacy and civil organizations, researchers, and academic institutions in a bid to improve services for epilepsy and other neurological diseases are in Ghana", noted WHO Representative to Ghana, Dr. Francis Kasolo at the stakeholders meeting on epilepsy and other neurological disorders in Ghana. (who.int)
We use sophisticated testing options for epilepsy, seizures and other brain disorders. (muschealth.org)
Although ADHD is present in focal and generalized epilepsies, some epileptic types or disorders, such as rolandic epilepsy and frontal epilepsy, were strongly associated with ADHD symptoms, especially in those individuals with newly diagnosed epilepsy, poorly controlled seizures, and abnormal electroencephalogram. (bvsalud.org)

Children with this type of epilepsy may have a family history of epilepsy. (rush.edu)
With this type of epilepsy children have typically been on at least two different medications at appropriate doses. (rush.edu)
There is not just one type of epilepsy. (dana.org)
Researchers at the Indian Institute of Science (IISc), in collaboration with All India Institute of Medical Sciences (AIIMS), Rishikesh, have developed an algorithm that they said can help decode brain scans to identify the occurrence and type of epilepsy. (thehindu.com)
The team ran their algorithm on a new set of EEG data from subjects for whom the classification (whether they had epilepsy, and if so, what type of epilepsy they had) was already known to the doctors. (thehindu.com)
We use testing to confirm an epilepsy diagnosis and determine the type of epilepsy with a high degree of accuracy. (muschealth.org)
Evaluating this activity helps us determine the type of epilepsy and which treatments may work best. (muschealth.org)

Like other forms of epilepsy, abdominal epilepsy is treated with anticonvulsant drugs, such as phenytoin . (wikipedia.org)
Cortical dysplasia, meaning disordered development of the cerebral cortex, is identified in 25 to 40 percent of children with the most severe and difficult-to-treat forms of epilepsy. (news-medical.net)
We study the gene "doublecortin," which is defective in some forms of epilepsy and mental retardation in humans," said Kerjan, lead author of the study. (news-medical.net)
But scientists found a genetic basis to specific forms of epilepsy, changing how its definition and treatment. (futurity.org)

This article details common concerns facing a parent who has a child with epilepsy, and how to handle them. (clevelandclinic.org)
Don't let a child with epilepsy swim alone. (clevelandclinic.org)
Parenting a child with epilepsy can be both rewarding and challenging. (sharecare.com)
The Rush Epilepsy Center focuses on selecting the best medication regimen for each child with epilepsy. (rush.edu)
Use these tips to make sure your child with epilepsy gets the care and support they need during the school day. (cdc.gov)
As your child with epilepsy returns to school, use these tips to ensure they get the care and support they need in school. (cdc.gov)
Use these tips to make sure your child with epilepsy has the support she needs to stay safe at school. (cdc.gov)

On the other hand, idiopathic generalized epilepsies (IGEs), which may represent some 15-20% of all epilepsies, are more common among females. (nih.gov)
If an underlying cause cannot be identified, a diagnosis of idiopathic or primary epilepsy is made. (uk.net)
Like all idiopathic (genetic) generalized epilepsies (IGEs), juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy (GGE), and both IGE and GGE are acceptable terms according to ILAE. (medscape.com)
Like the entire group of idiopathic (genetic) generalized epilepsies (IGEs), genetic factors play a definite role, hence the term genetic generalized epilepsy (GGE). (medscape.com)

Rush's epilepsy program, in collaboration with the Epilepsy Foundation of North/Central Illinois, is developing portable communication technologies that will allow epileptologists to take specialized epilepsy care to children with refractory epilepsy in rural communities that lack this expertise. (rush.edu)
Data to date assessing psychopathology in refractory epilepsy patients is conflicting. (rcsi.com)
In a subgroup of medically refractory epilepsy patients, surgical intervention is considered. (rcsi.com)
This study is prospective cohort study which examined a group of patients with medically refractory epilepsy, and also examined a cohort who proceeded to surgery before and after surgery. (rcsi.com)
The findings of this study demonstrated the high prevalence of psychiatric comorbidity (49%) in patients with medically refractory epilepsy. (rcsi.com)
Overall, this study has demonstrated that undergoing surgery for medically refractory epilepsy had an overall positive Impact on mental health with a significant reduction in the severity and prevalence of psychiatric symptoms and an improved quality of life. (rcsi.com)

When clinical and serological clues suggest an autoimmune basis for medically intractable epilepsy, early-initiated immunotherapy may improve seizure outcome," the authors conclude. (medindia.net)
Intractable epilepsy refers to recurrent seizures that are not well controlled with medication. (rush.edu)
It is important to correctly diagnose medically intractable epilepsy in children and to identify those children whose medically refractory, localization-related seizures may be surgically remediable as soon as possible to optimize the surgical outcome. (medscape.com)
They also outline the presurgical diagnostic evaluation process for pharmacologically intractable epilepsy in children who may be candidates for surgical treatment of localization-related seizures. (medscape.com)
The treatment of children with medically intractable epilepsy is both challenging and rewarding. (medscape.com)
Cite this: Pharmacologically Intractable Epilepsy In Children: Diagnosis and Preoperative Evaluation - Medscape - Sep 01, 2008. (medscape.com)

Epilepsy Employment Group (EEG) is a Job Search Support Group for people living with epilepsy. (epilepsytoronto.org)
Statistics from the Centers for Disease Control and Prevention (CDC) show that more people are living with epilepsy in the United States than ever before. (intermountainhealthcare.org)
That was over a year ago, and since then my family has been living with epilepsy . (everything2.com)
From employment and transportation to education and housing, people living with epilepsy face these issues and many more on a daily basis. (epilepsyontario.org)
Canadians have spoken out about the social consequences and health obstacles they face while living with epilepsy. (epilepsyontario.org)
Many people living with epilepsy are reluctant to disclose their condition to co-workers or friends out of fear of what they might think. (epilepsyontario.org)
Our message is loud and clear: we want to improve the quality of life for the 140,000 Ontarians who are living with epilepsy. (epilepsyontario.org)
Transforming the lives of people living with epilepsy through world-leading research, advocacy and care. (runbritain.com)
AptarGroup, Inc. (NYSE: ATR), a global leader in drug delivery, consumer product dispensing and active packaging solutions, today announced that its patented Unidose Liquid System is the device delivering the first and only nasal rescue treatment approved by the U.S. FDA, which has recently launched in the U.S. to treat acute repetitive seizures in people living with epilepsy. (aptar.com)
Thank you for supporting people living with epilepsy! (epilepsyfoundation.org.au)

The scientists hope that their findings - based on a mouse model of severe epilepsy - may someday pave the way for improved treatments of childhood epilepsy, which affects more than two percent of children worldwide. (news-medical.net)
Through clinical trials, epilepsy experts at Rush also participate in the study of new medical treatments that are not otherwise widely available. (rush.edu)
For hard-to-treat epilepsy, testing enables us to plan your treatments meticulously. (muschealth.org)
No treatments could stop his epilepsy, so as a last resort surgeons removed a third of his brain 's right hemisphere just before his seventh birthday. (newscientist.com)
Over the nearly 100 years of use, from being a last resource in the therapeutic algorithm , the diet has become one of the four main treatments for patients with difficult-to- control epilepsy together with antiepileptic drugs , surgery , and vagus nerve stimulation . (bvsalud.org)

[8] Distinguishing features of abdominal epilepsy include (1) Abnormal laboratory, radiographic, and endoscopic findings revealing paroxysmal GI manifestations of unknown origin (2) CNS symptoms (3) Abnormal EEG . (wikipedia.org)
Abdominal epilepsy is marked by GI symptoms such as abdominal pain followed by uncontrollable vomiting , usually preceded by lethargy . (wikipedia.org)
Lethargy and confusion is the most common neurological symptoms associated with abdominal epilepsy. (wikipedia.org)
Criteria for diagnosis of abdominal epilepsy includes frequent periodic abdominal symptoms, an abnormal electroencephalogram (EEG) and significant improvement of gastrointestinal symptoms after taking anti-seizure medication. (wikipedia.org)
Symptoms that are persistent throughout or persist for hours are less probable to be indications of abdominal epilepsy. (wikipedia.org)
Convulsions, impairment in consciousness and other neurological symptoms are ought to be considered along with the gastrointestinal symptoms when diagnosing abdominal epilepsy. (wikipedia.org)
Find out everything you need to know about epilepsy including symptoms, treatment, causes, management and more. (sharecare.com)
Seizures, transient signs or symptoms caused by abnormal surges of electrical activity in the brain, can result from epilepsy, a neurologic disorder characterized by abnormal electrical brain activity causing recurrent, unprovoked seizures, or from other inciting causes, such as high fever or substance abuse. (medscape.com)
Patients with epilepsy may experience warning symptoms before a seizure. (nbc-2.com)
People with Lafora progressive myoclonus epilepsy generally survive up to 10 years after symptoms first appear. (medlineplus.gov)
Although Lafora bodies are found in many of the body's tissues, the signs and symptoms of Lafora progressive myoclonus epilepsy are limited to the nervous system. (medlineplus.gov)
People with Epilepsy, Parkinson's Disease, Attention Deficit Disorder (ADD) or addictions may be able to learn how to 'think themselves better' by altering their brain waves to improve their symptoms. (epilepsytalk.com)
Two of the children in each family demonstrated similar symptoms that can be connected to a severe variant of infant epilepsy with MPSI (Migrating Partial Seizures of Infancy). (ki.se)
METHODS: Subjects 18 or older with localization-related epilepsy (LRE) and =3 seizures per month maintained an e-diary, reporting a.m./p.m. data daily, including mood, premonitory symptoms, and all seizures. (cdc.gov)

The US Centers for Disease Control and Prevention estimates that about 3.4 million people in the United States have epilepsy, including 470,000 children. (medscape.com)

If your patient has not undergone diagnostic testing, search here to find a comprehensive epilepsy center that can evaluate your patient, including determining if the RNS System is right for them. (amazonaws.com)

Laboratory testing focussed on epileptic seizures in particular because of the challenges of long-term treatment with current anti-epileptic drugs and the large number of patients with drug-resistant epilepsy. (epilepsy.org.nz)
If you've been looking for an epilepsy camp in Texas for your child or a summer camp for epileptic adults , you've come to the right place. (campforall.org)
Our summer camp for epileptic children is staffed by people who are specially trained to work with kids who have epilepsy, so you can feel confident that your child is in a safe environment while expanding their horizons and developing confidence and independence. (campforall.org)
Epilepsy is defined as a brain disorder characterized by an enduring predisposition to generate epileptic seizures and by the neurobiologic, cognitive, psychological, and social consequences of this condition. (medscape.com)
If you hear the mother of someone with epilepsy saying, "Well, the seizure began with the individual's head turning far to the right-hand side, it got stuck there, then there was stiffening of one hand and the individual made a guttural noise, lost posture, and fell to the ground, and then stiffened all over and started to shake," you would be pretty sure that was an epileptic seizure. (medscape.com)

For the second consecutive year, the University of Minnesota, with help from the Epilepsy Foundation of Minnesota, is dedicating a game to raising awareness for a disease that affects 60,000 people in the state and 3 million nationwide. (twincities.com)

Cite this: FDA Clears First Smart Watch to Detect Seizures, Manage Epilepsy - Medscape - Feb 06, 2018. (medscape.com)
Adaptation and validation of QOLIE-31 were performed in July 2018 among 118 patients with epilepsy in the Fez-Meknes region. (who.int)

Lafora progressive myoclonus epilepsy is a brain disorder characterized by recurrent seizures (epilepsy) and a decline in intellectual function. (medlineplus.gov)

Epilepsy is one of the most common serious chronic neurological conditions affecting people of all ages globally, with peaks in incidence rates in children and in adults over the age of 60. (who.int)
Epilepsy is a neurological disease where the brain emits sudden bursts of electrical signals in a short amount of time. (thehindu.com)
Epilepsy is a neurological disordered characterized by recurring seizures. (somervillegardensnj.com)

The Rush pediatric epilepsy team focuses on helping children with epilepsy thrive and reach their fullest potential cognitively, emotionally and socially. (rush.edu)
Learn more about pediatric epilepsy providers at Rush. (rush.edu)

Epilepsy is a disorder of the brain that triggers recurrent seizures. (cdc.gov)
Epilepsy is described as the tendency to have recurrent seizures. (uk.net)

Embrace was tested in a clinical study involving 135 patients with epilepsy who were admitted to epilepsy monitoring units for continuous monitoring with video electroencephalography while simultaneously wearing the device, which records electrodermal activity. (medscape.com)
Subtypes of post-traumatic epilepsy: clinical, electrophysiological, and imaging features. (medscape.com)
Clinical trials are ongoing with a drug that, if successful, will compensate for the disrupted regulation and ameliorate the disease in small children with epilepsy, says Dr. Wedell. (ki.se)
My talk was getting people to pay attention to what the person is telling you to understand better about seizure type and presence or absence of epilepsy, and how that might relate to doing a very good, high-quality clinical trial. (medscape.com)
Yet, there's no specific test for epilepsy, so it's a clinical diagnosis. (medscape.com)

If you were able to capture a seizure on video EEG monitoring, that would be confirmation of a diagnosis of epilepsy. (medscape.com)

In the later stages of Lafora progressive myoclonus epilepsy, myoclonus often occurs continuously and affects the entire body. (medlineplus.gov)
Several types of seizures commonly occur in people with Lafora progressive myoclonus epilepsy. (medlineplus.gov)
The prevalence of Lafora progressive myoclonus epilepsy is unknown. (medlineplus.gov)
Lafora progressive myoclonus epilepsy can be caused by mutations in either the EPM2A gene or the NHLRC1 gene. (medlineplus.gov)
Researchers have discovered that people with Lafora progressive myoclonus epilepsy have distinctive clumps called Lafora bodies within their cells. (medlineplus.gov)
Mutations in the EPM2A and NHLRC1 genes account for 80 percent to 90 percent of all cases of Lafora progressive myoclonus epilepsy. (medlineplus.gov)

The study included patients with autoimmune epilepsy as the predominant neurologic feature, so their main presenting symptom was seizures. (medscape.com)

As previously mentioned, it is difficult to distinguish frontal lobe seizures from nonepileptic events based on history alone, and patients with frontal lobe epilepsy may be misdiagnosed as having psychogenic nonepileptic events. (medscape.com)
Brodtkorb E, Picard F. Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy. (medscape.com)
Incidence of sudden unexpected death in nocturnal frontal lobe epilepsy: a cohort study. (medscape.com)
The syndrome of frontal lobe epilepsy: characteristics and surgical management. (medscape.com)
Baud MO, Vulliemoz S, Seeck M. Recurrent secondary generalization in frontal lobe epilepsy: Predictors and a potential link to surgical outcome? (medscape.com)
Factors predictive of the outcome of frontal lobe epilepsy surgery. (medscape.com)
We plan to include and compare patients with temporal and frontal lobe epilepsy as well as healthy volunteers. (uniklinik-freiburg.de)

Pyridoxine-dependent epilepsy is caused by a specific genetic problem and starts when a child is a newborn or baby. (rush.edu)
Epilepsy may occur as a result of a genetic disorder or a brain injury, but many people never know the cause. (thestatesman.com)

The condition affects about 40 per cent of all epilepsy sufferers, about 100,000 Australians, and is caused by an electrical storm that emanates from a single point in the brain. (edu.au)
To demystify epilepsy-which affects almost four million people in the US-a doctoral candidate presented "The Science of Epilepsy" with explanations of how seizures work and what to do if someone is having one. (dana.org)
Why is there still so much stigma attached to epilepsy, which currently affects about one in 26 people in the US? (dana.org)
There is poor knowledge about epilepsy among teachers in Morocco, and this unawareness negatively affects teachers' attitudes towards people with epilepsy (8). (who.int)
FORT LAUDERDALE, Fla. (Ivanhoe Newswire) - Epilepsy affects three million people every day. (ivanhoe.com)

In 2016, a Maryland man was charged with aggravated assault with a deadly weapon after deliberately tweeting a strobing GIF to a journalist with epilepsy. (kivitv.com)
Fast Five Quiz: Test Your Knowledge of Epilepsy and Seizure-related Conditions - Medscape - Jan 12, 2016. (medscape.com)

Connect with other adults with epilepsy and enjoy the beautiful gardens and lake walk at Munsinger Clemens Gardens. (epilepsyfoundationmn.org)
Furthermore, adults with epilepsy have many social concerns (2-4), like restrictions in driving and professional constraints (5-7). (who.int)

A person with epilepsy is not contagious and cannot give epilepsy to another person. (cdc.gov)
In 2013, IBE awarded her as an 'outstanding person with epilepsy. (internationalepilepsyday.org)

[ 5 ] These findings reinforce the importance of understanding factors associated with ED avoidance among persons with epilepsy or seizure, the importance that all eligible persons be up to date ¶ with COVID-19 vaccination, and the need to encourage persons to seek appropriate care for seizure-related emergencies** to prevent adverse outcomes. (medscape.com)
SIGNIFICANCE: Some persons with epilepsy can self-predict seizures. (cdc.gov)

Antiepileptic drugs (AEDs) are the mainstay of treatment for epilepsy, but seizures continue in one-third of patients despite appropriate AED therapeutic trials," the authors write as background in the study. (medindia.net)
Ideally, treatment for epilepsy should prevent seizures before they occur. (epilepsy.org.nz)
Are you currently on treatment for epilepsy? (towncentresurgeryluton.nhs.uk)

[6] It has been described as a type of temporal lobe epilepsy . (wikipedia.org)
[14] Any pathophysiological changes in the M2 portion of cerebral artery which flows through lateral sulcus are associated with the epilepsies of the temporal and parietal regions. (wikipedia.org)

An epilepsy patient, who had not responded to any drug or surgical treatment, underwent an innovative procedure last week, which is supposed to prevent seizures caused by the disorder, for the first time in Israel. (ynetnews.com)
In collaboration with neurologists Dr Chris Plummer and Professor Mark Cook, neurosurgeon Associate Professor Michael Murphy and imaging specialist Simon Vogrin of Melbourne's St Vincent's Hospital, Professor David Liley of Swinburne's Brain and Psychological Sciences Research Centre is using MEG/EEG to locate and help plan surgical treatment for patients with focal epilepsy. (edu.au)
Psychiatric co morbidity in epilepsy, psychiatric and psychosocial morbidity before and after surgical treatment. (rcsi.com)
Barry, H. Psychiatric co morbidity in epilepsy, psychiatric and psychosocial morbidity before and after surgical treatment. (rcsi.com)
Update on surgical treatment of the epilepsies. (symptoma.com)
Summary of the Second International Palm Desert Conference on the Surgical Treatment of the Epilepsies» (1992). (symptoma.com)

The idea of using the compounds found in marijuana to treat epilepsy is gaining appeal. (healthline.com)
Can a Dietary Approach Help Treat Epilepsy in Adults? (sharecare.com)

Researchers at the University of California, San Diego School of Medicine have discovered that convulsive seizures in a form of severe epilepsy are generated, not on the brain's surface as expected, but from within the memory-forming hippocampus. (news-medical.net)
But the severe epilepsy that is associated with lissencephaly was never displayed in any of the previous animals, so the team kept removing gene after gene until they hit upon a strain that showed epilepsy. (news-medical.net)
Thinking that the deaths might be due to epilepsy, the scientists recorded electroencephalograms, which measure electrical activity produced by the firing of neurons in the brain, and found severe epilepsy in all of the mice tested. (news-medical.net)
A boy who had a large portion of his brain removed to relieve his severe epilepsy is still able to function normally, showing how adaptable our brains can be. (newscientist.com)

The US Food and Drug Administration (FDA) has cleared for marketing the Embrace smart watch (Empatica Inc) for seizure tracking and epilepsy management. (medscape.com)

Women's Health and Epilepsy: Are we meeting AAN Quality Measures? (umaryland.edu)

In many parts of the world, people with epilepsy and their families are subjected to stigmatization and discrimination as a result of the misconceptions and negative attitudes that surround epilepsy, including the belief that epilepsy is the result of possession by evil spirits or that it is contagious. (who.int)

Learn more about active epilepsy and find state-specific prevalence estimates on our Data and Statistics page. (cdc.gov)
There are almost no studies on epilepsy incidence and prevalence in Morocco. (who.int)
Epilepsy is a common disease with an incidence of 20-70 per 100 000 annually and prevalence of 0.5-1 % of the population. (rcsi.com)
Despite 20 years of ivermectin mass distribution in the Mahenge area, Tanzania , the prevalence of onchocerciasis and epilepsy has remained high in rural villages. (bvsalud.org)

Benign rolandic epilepsy is the most common cause of seizures in healthy school-aged children. (rush.edu)

Epilepsy is a brain disorder in which clusters of nerve cells (known as neurons) sometimes signal abnormally, often causing recurring seizures. (rush.edu)
Introduction Epilepsy is a brain disorder in which clusters of nerve cells,or neurons, in the brain sometimes signal abnormally. (myhealth.gov.my)

In people with focal epilepsy impairments in social cognition are under-researched. (uniklinik-freiburg.de)
We hope that this study will contribute to a better understanding of social cognition and the consequences of social cognitive deficits for daily living in people with focal epilepsy, and ultimately lead to the formulation of effective therapeutic strategies. (uniklinik-freiburg.de)
Focal epilepsy occurs when the erratic signals are confined to a specific region in the brain. (thehindu.com)
The RNS System is for individuals 18 and older who have focal epilepsy and have tried two or more medications without finding seizure control. (amazonaws.com)
Does your patient have focal epilepsy? (amazonaws.com)

There is research to suggest that one or more genes may cause epilepsy. (intermountainhealthcare.org)
A few different things can cause epilepsy including genetics and infections. (sharecare.com)

In 2015, 1.2% of the total US population had active epilepsy. (cdc.gov)
According to the latest estimates, about 0.6% of children aged 0-17 years have active epilepsy. (cdc.gov)
a Active epilepsy is defined as adults, participating in the 2015 NHIS, who reported a history of doctor-diagnosed epilepsy or seizure disorder and either were currently taking medication to control it, or had one or more seizures in the past year, or both. (cdc.gov)
Zack MM, Kobau R. National and state estimates of the numbers of adults and children with active epilepsy - United States, 2015. (cdc.gov)
In 2015, about 3.4 million people reported having active epilepsy in the United States. (cdc.gov)

Russ SA, Larson K, Halfon N. A national profile of childhood epilepsy and seizure disorder. (cdc.gov)
Behavioral disinhibition and antiepileptic treatment in childhood epilepsy: A retrospective cohort study. (uu.nl)
Objective To test whether specific classes of antiepileptic drugs increase the risk for behavioral disinhibition, a frequent complication of treatment of childhood epilepsy. (uu.nl)
Significance This exploration of behavioral disinhibition in relation to antiepileptic drug treatment indicates that GABA potentiating drugs are specifically associated with behavioral problems during treatment of childhood epilepsy. (uu.nl)
Our findings may be related to the increasing evidence for a role for excitatory actions of GABA in childhood epilepsy. (uu.nl)

Special diets can help some children with epilepsy. (medlineplus.gov)
People with epilepsy often suffer from comorbidities such as depression and anxiety, associated intellectual disabilities (especially in children) and physical injuries (for instance, fractures and burns). (who.int)
In some settings, children with epilepsy may not be allowed to attend school, while adults with the condition may not be able to find suitable employment or to marry. (who.int)
Abdominal epilepsy is a rare condition most frequently found in children, consisting of gastrointestinal disturbances caused by epileptiform seizure activity . (wikipedia.org)
Approximately 19 months after a quality improvement project designed to reduce ED visits by children with epilepsy was implemented, a 28% reduction in ED visits and a 43% reduction in unplanned hospitalizations was demonstrated. (medpagetoday.com)
How do children deal with epilepsy? (clevelandclinic.org)
Children with an illness such as epilepsy might develop emotional problems, such as poor self-esteem, anxiety , or depression . (clevelandclinic.org)
Children with epilepsy might be teased by other children. (clevelandclinic.org)
Anxiety and depression are seen frequently in children with epilepsy sometimes even before the child has the first seizure. (clevelandclinic.org)
What should I know about children and epilepsy medicine? (clevelandclinic.org)
These children often come to the attention of specialists due to stagnation in the acquisition of language and balance skills and accompanying epilepsy. (news-medical.net)
Newswise - Results from a double-blind, placebo-controlled trial published in The New England Journal of Medicine revealed that children with Dravet syndrome, a severe form of epilepsy, had fewer seizures after taking a daily oral solution of the cannabis compound called cannabidiol, which does not have the psychoactive properties of marijuana. (newswise.com)
They work with families and schools to help children with epilepsy succeed despite their challenges. (rush.edu)
Child Life specialists at Rush offer children age-appropriate activities and education to help them cope with having epilepsy, while also preparing them for medical tests, procedures and surgery. (rush.edu)
In fact, the surge in popularity of cannabis for patients with pharmacoresistant epilepsy seems to stem from publicity surrounding MMJ for children, highlighting in particular oils made from strains with high CBD and low THC. (veterinarypracticenews.com)
The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. (epnet.com)
TECC received a grant from the Maternal Child Health Bureau at the Health Resources and Services Administration to utilize telehealth technologies to expand access to high-quality specialty and primary care for children and youth with epilepsy. (bmc.org)
He saw the coach speak at a gala last year and also at Camp Oz for children with epilepsy near Hudson, Wis. (twincities.com)
We partner with organizations like the Epilepsy Foundation of Texas Houston/Dallas/Fort Worth to create a Texas summer camp for epilepsy that recognizes the special needs of children and adults with this condition. (campforall.org)
Parents of teens may have specific concerns about how to manage epilepsy as their children become more independent. (cdc.gov)
The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care. (bvsalud.org)

She educates people in Mumbai on epilepsy and campaigns against the stigma attached to the disease. (internationalepilepsyday.org)
There, they can learn more about epilepsy, what a seizure looks like, stigma and bullying, and how to provide seizure first aid. (cdc.gov)
On the other hand, the Epilepsy Stigma Scale may correlate with the Rosenberg Self-esteem scale. (who.int)

Anatomy8

Diseases28

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Psychiatry and Psychology5

Phenomena and Processes5

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science1

Named Groups2

Health Care5

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes. (1/4971)

Characterization of nodular neuronal heterotopia in children. (2/4971)

Oligodendroglial vacuolar degeneration in the bilateral motor cortices and astrocytosis in epileptic beagle dogs. (3/4971)

Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic. (4/4971)

Adjunctive therapy in epilepsy: a cost-effectiveness comparison of two AEDs. (5/4971)

Willingness to pay: a feasible method for assessing treatment benefits in epilepsy? (6/4971)

Outcome of pregnancies in epileptic women: a study in Saudi Arabia. (7/4971)

Information exchange in an epilepsy forum on the World Wide Web. (8/4971)

Epilepsy

Epilepsy, Generalized

Epilepsy, Temporal Lobe

Epilepsies, Myoclonic

Anticonvulsants

Epilepsy, Reflex

Myoclonic Epilepsy, Juvenile

Epilepsy, Tonic-Clonic

Epilepsy, Complex Partial

Epilepsy, Frontal Lobe

Electroencephalography

Seizures

Epilepsy, Rolandic

Epilepsy, Post-Traumatic

Sclerosis

Seizures, Febrile

Carbamazepine

Status Epilepticus

Pilocarpine

Anterior Temporal Lobectomy

Piracetam

Myoclonic Epilepsies, Progressive

Magnetic Resonance Imaging

Death, Sudden

Valproic Acid

Neurosurgical Procedures

Malformations of Cortical Development

Hippocampus

Temporal Lobe

Psychosurgery

Epilepsy, Benign Neonatal

Ketogenic Diet

Kindling, Neurologic

Vagus Nerve Stimulation

Brain

Video Recording

Phenytoin

Vigabatrin

Spasms, Infantile

Neurosurgery

Convulsants

Triazines

Epilepsy, Partial, Motor

Age of Onset

Intellectual Disability

Electrodes, Implanted

Cerebral Cortex

Functional Laterality

Neurocysticercosis

Nurse Clinicians

Ethosuximide

Dentate Gyrus

Kainic Acid

Channelopathies

Retrospective Studies

Disease Models, Animal

Brain Diseases

Neurology

Pentylenetetrazole

Treatment Outcome

Dominance, Cerebral

Amobarbital

Drug Resistance

Brain Mapping

Magnetoencephalography

Syndrome

Primidone

Receptors, GABA-A

Neuropsychological Tests

Witchcraft

Neurons

Mossy Fibers, Hippocampal

Tuberous Sclerosis

Neocortex

Follow-Up Studies

Famous Persons

Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes. (1/4971)

Characterization of nodular neuronal heterotopia in children. (2/4971)

Oligodendroglial vacuolar degeneration in the bilateral motor cortices and astrocytosis in epileptic beagle dogs. (3/4971)

Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic. (4/4971)

$Promoting faster pathways to surgery: a clinical audit of patients with refractory epilepsy | BMC Neurology | Full Text$ Promoting faster pathways to surgery: a clinical audit of patients with refractory epilepsy | BMC Neurology | Full Text