The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.
The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The network of channels formed at the termination of the straight SEMINIFEROUS TUBULES in the mediastinum testis. Rete testis channels drain into the efferent ductules that pass into the caput EPIDIDYMIS.
Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific. They are important molecular agents in the process of sperm maturation.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Paired ducts in the human male through which semen is ejaculated into the urethra.
The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct.
Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)
Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.
Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.
A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.
A count of SPERM in the ejaculum, expressed as number per milliliter.
The convoluted tubules in the TESTIS where sperm are produced (SPERMATOGENESIS) and conveyed to the RETE TESTIS. Spermatogenic tubules are composed of developing germ cells and the supporting SERTOLI CELLS.
The surgical removal of one or both testicles.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Liquid components of living organisms.
The epithelium lining the seminiferous tubules composed of primary male germ cells (SPERMATOGONIA) and supporting SERTOLI CELLS. As SPERMATOGENESIS proceeds, the developing germ cells migrate toward the lumen. The adluminal compartment, the inner two thirds of the tubules, contains SPERMATOCYTES and the more advanced germ cells.
The measurement of an organ in volume, mass, or heaviness.
Pathological processes of the TESTIS.
Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Achievement of full sexual capacity in animals and in humans.
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.
Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.
An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.
An oviparous burrowing mammal of the order Monotremata native to Australia, Tasmania, and New Guinea. It has hair mingled with spines on the upper part of the body and is adapted for feeding on ants.
Surgical anastomosis or fistulization of the spermatic ducts to restore fertility in a previously vasectomized male.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Chemical substances or agents with contraceptive activity in males. Use for male contraceptive agents in general or for which there is no specific heading.
The posterior filiform portion of the spermatozoon (SPERMATOZOA) that provides sperm motility.
A chlorinated PROPANEDIOL with antifertility activity in males used as a chemosterilant in rodents.
A family of herbivorous leaping MAMMALS of Australia, New Guinea, and adjacent islands. Members include kangaroos, wallabies, quokkas, and wallaroos.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Surgical removal or artificial destruction of gonads.
The anterior portion of the spermatozoon (SPERMATOZOA) that contains mainly the nucleus with highly compact CHROMATIN material.
An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Either of a pair of tubular structures formed by DUCTUS DEFERENS; ARTERIES; VEINS; LYMPHATIC VESSELS; and nerves. The spermatic cord extends from the deep inguinal ring through the INGUINAL CANAL to the TESTIS in the SCROTUM.
A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.
Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA.
DEFENSINS found mainly in epithelial cells.
Carrier proteins produced in the Sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. They participate in the transport of androgens. Androgen-binding protein has the same amino acid sequence as SEX HORMONE-BINDING GLOBULIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
A species of macaque monkey that mainly inhabits the forest of southern India. They are also called bonnet macaques or bonnet monkeys.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
A selective pre- and post-emergence herbicide. (From Merck Index, 11th ed)
A cystic dilation of the EPIDIDYMIS, usually in the head portion (caput epididymis). The cyst fluid contains dead SPERMATOZOA and can be easily differentiated from TESTICULAR HYDROCELE and other testicular lesions.
A cutaneous pouch of skin containing the testicles and spermatic cords.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.
An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.

Inhibition by amiloride of sodium-dependent fluid reabsorption in the rat isolated caudal epididymis. (1/2450)

The rate of fluid reabsorption was studied in the rat isolated caudal epididymal sac in vitro. 2 Part of the fluid reabsorption was found to be dependent on intraluminal Na+. Amiloride (0.1 mM) completely inhibited this component of fluid reabsorption. 3 The log dose-inhibition curve to amiloride was sigmoid and the IC50 value was found to be 1.6 muM.  (+info)

Morphology of the epididymal region and ductus deferens of the turkey (Meleagris gallopavo). (2/2450)

The ductal system of the reproductive tract of the male domestic turkey was studied by gross dissection and light microscopy of paraffin and Epon embedded tissues. The succession of ductules as one passes caudally from the testis was as follows: seminiferous tubules; rete testis; ductuli efferentes; connecting ductules; ductus epididymidis; ductus deferens; receptaculum ductus deferentis; papilla ductus deferentis. Non-ciliated cells of the male tract consisted of squamous and low cuboidal cells of the rete testis, granulated columnar cells lining the ductuli efferentes and connective ductules; agranulated columnar cells which formed the epithelium of the ductus epididymidis, ductus deferens, receptaculum and papilla ductus deferentis; and basal cells which were found in increasing number from the ductuli efferentes to the papilla. The basal cells had a reduced amount of cytoplasm and stained more intensely than the other cell types. Ciliated cells were apparent in the ductuli efferentes and connecting ductules, and these consistently stained lighter than the non-ciliated cells. Non-ciliated columnar cells of the ductuli efferentes and connecting ductules contained chromatophilic granules. Cytoplasmic blebbing into the ductal lumina was found associated with these non-ciliated cells as well as the agranular cells of the ductus epididymidis and deferens. Evidence obtained from this study suggests that the non-ciliated cells of the ductuli efferentes, ductus epididymidis and ductus deferens have a contribution to make to the seminal plasma by apocrine secretion.  (+info)

Glutathione-independent prostaglandin D2 synthase in ram and stallion epididymal fluids: origin and regulation. (3/2450)

Microsequencing after two-dimensional electrophoresis revealed a major protein, glutathione-independent prostaglandin D2 synthase (PGDS) in the anterior epididymal region fluid of the ram and stallion. In this epididymal region, PGDS was a polymorphic compound with a molecular mass around 30 kDa and a range of pI from 4 to 7. PGDS represented 15% and 8% of the total luminal proteins present in this region in the ram and stallion, respectively. The secretion of the protein as judged by in vitro biosynthesis, and the presence of its mRNA as studied by Northern blot analysis, were limited to the proximal caput epididymidis. Using a specific polyclonal antibody raised against a synthetic peptide, PGDS was found throughout the epididymis, decreasing in concentration toward the cauda region. PGDS was also detected in the testicular fluid and seminal plasma by Western blotting. Castration and efferent duct ligation in the ram led to a decrease in PGDS mRNA and secretion. PGDS mRNA was not detected in the stallion 1 mo after castration, and it was restored by testosterone supplementation. This study showed that PGDS is present in the environment of spermatozoa throughout the male genital tract. Its function in the maturation and/or protection of spermatozoa is unknown.  (+info)

Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. (4/2450)

An acidic environment is important for sperm maturation in the epididymis and also helps to maintain mature sperm in an immotile state during storage in this organ. Both an Na+/H+ exchanger and an H+ATPase have been implicated in this process. The H+ATPase is concentrated in specialized apical (and/or narrow) and clear cells of the epididymis, while the Na+/H+ exchanger has not yet been localized in situ. As in other proton-secreting epithelia, bicarbonate transport occurs in the epididymis, where it is implicated in luminal acidification. In this study we used an antibody raised against a fusion protein (maltose-binding protein: MBP-NBC-5) from the C-terminus of the recently cloned rat kidney Na+/HCO3- cotransporter (NBC) to localize this protein in the epididymis and vas deferens of the rat. The distribution of the respective mRNA was mapped by in situ hybridization. NBC message was strongly expressed in the initial segment and the intermediate zone of the epididymis, and the NBC-5 antibody gave a strong basolateral staining in both principal cells and apical/narrow cells in this region. Western blotting revealed a single band at about 160 kDa in the epididymis. The intensity of staining as well as mRNA levels decreased in the cauda epididymidis and in the vas deferens, where only weak staining was seen. Basolateral NBC may function in parallel with apical proton secretion to regulate luminal acidification and/or bicarbonate reabsorption in the excurrent duct system.  (+info)

Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis. (5/2450)

Gamma-glutamyl transpeptidase (GGT) mRNA-IV and polyomavirus enhancer activator 3 (PEA3) mRNA are highly expressed in the initial segment of the rat epididymis, and both are regulated by testicular factors. PEA3 protein in rat initial segment nuclear extracts has been shown to bind to a PEA3/Ets binding motif, which is derived from the partially characterized GGT mRNA-IV promoter region. This suggests that PEA3 may be involved in regulating transcription from the rat GGT mRNA-IV gene promoter in the initial segment. Using DNA oligonucleotide primers and DNA sequencing analysis, an approximately 1500-basepair (bp) DNA sequence at the 5' region of the promoter was obtained. Using transient transfection, PEA3 activated transcription of the rat GGT mRNA-IV promoter only in cultured epididymal cells from the rat initial segment, but not in Cos-1 or NRK-52E cells. Promoter deletion analysis indicated that a PEA3/Ets binding motif between nucleotides -22 and -17 is the functional site for PEA3 to activate transcription of GGT promoter IV and that an adjacent Sp1 binding motif is also required to maintain promoter IV activity in epididymal cells. Transcriptional activation of promoter IV was shown to be epididymal cell-specific and PEA3-specific. In addition, PEA3 may act as a weak repressor for transcription of promoter IV, probably using a PEA3/Ets binding motif(s) distal to the transcription start site. A model of how PEA3 is involved in the regulation of transcription of GGT promoter IV in epididymal cells is proposed.  (+info)

An intact sperm nuclear matrix may be necessary for the mouse paternal genome to participate in embryonic development. (6/2450)

We have been interested in determining the minimally required elements in the sperm head that are necessary in order for the paternal genome to participate in embryogenesis. We used an ionic detergent, mixed alkyltrimethylammonium bromide (ATAB), plus dithiothreitol (DTT) to remove the acrosome and almost all of the perinuclear theca, leaving only the sperm nucleus morphologically intact. We also tested the stability of the sperm nuclear matrix by the ability to form nuclear halos. Sperm nuclei washed in freshly prepared 0.5% ATAB + 2 mM DTT completely decondensed when extracted with salt, but nuclei washed in the same buffer that was 1 wk old, and then extracted with salt, produced nuclear halos, indicating stable nuclear matrices. When we treated sperm heads with freshly prepared ATAB+DTT and injected them into oocytes, none of the oocytes developed into live offspring. In contrast, sperm heads treated in the same way but with 1-wk-old ATAB+DTT solution could support development of about 30% of the oocytes to live offspring. Electron microscopy demonstrated that most of the perinuclear theca had been removed in both cases. These data suggest that at least in the mouse, the only component of the spermatozoa that is crucial for participation in embryologic development is the sperm nucleus with a stable nuclear matrix.  (+info)

Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence. (7/2450)

With slight modification of a trypsin digestion technique, Rickettsia rickettsii were demonstrated specifically by immunofluorescence staining in Formalin-fixed, paraffin-embedded tissue sections from a human, rhesus monkey, and guinea pig with Rocky Mountain spotted fever and in infected membranes from a chicken embryo. Tissues were cut at 4 micron and, using geltain as a tissue adhesive, were hydrated in a routine manner. Sections were then digested in refrigerated 0.1% trypsin for 16 h, washed, and stained specifically for R. rickettsii by direct or indirect immunofluorescence. Rickettsial organisms were localized in affected vessels of the mammalian species and within the yolk sac epithelium of the chicken embryo. Specificity was confirmed by adsorbing antibody conjugates with R. rickettsii organisms. Trypsin digestion probably decreased tissue proteins which interfered with immunochemical attachment of antibody to the rickettsiae. The technique is valuable in that a diagnosis of Rocky Mountain spotted fever can be confirmed from Formalin-fixed tissues processed in a routine manner.  (+info)

Reversing adipocyte differentiation: implications for treatment of obesity. (8/2450)

Conventional treatment of obesity reduces fat in mature adipocytes but leaves them with lipogenic enzymes capable of rapid resynthesis of fat, a likely factor in treatment failure. Adenovirus-induced hyperleptinemia in normal rats results in rapid nonketotic fat loss that persists after hyperleptinemia disappears, whereas pair-fed controls regain their weight in 2 weeks. We report here that the hyperleptinemia depletes adipocyte fat while profoundly down-regulating lipogenic enzymes and their transcription factor, peroxisome proliferator-activated receptor (PPAR)gamma in epididymal fat; enzymes of fatty acid oxidation and their transcription factor, PPARalpha, normally low in adipocytes, are up-regulated, as are uncoupling proteins 1 and 2. This transformation of adipocytes from cells that store triglycerides to fatty acid-oxidizing cells is accompanied by loss of the adipocyte markers, adipocyte fatty acid-binding protein 2, tumor necrosis factor alpha, and leptin, and by the appearance of the preadipocyte marker Pref-1. These findings suggest a strategy for the treatment of obesity by alteration of the adipocyte phenotype.  (+info)

Electron microscopic study was made on the water reabsorption of the epithelial cells of the rat cauda epididymidis. It was shown that when the epididymal duct was reabsorbing water at a maximal rate, widely dilated intercellular spaces were seen. It is suggested that the standing gradient model of water reabsorption first proposed for the gall bladder may also operate in the cauda epididymidis ...
β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological properties led us to conclude that the increased activity was not due to the expression of an isoform unrelated to the HEX A and B present in other human tissues. Measurement of enzyme levels in the three distinct epididymal regions revealed that in any given sample, activity was higher in the caput than in the corpus or cauda. Moreover, we found a striking correlation between β-HEX activity in the caput region and concentrations of blood testosterone, suggesting a possible involvement of the hormone in modulating enzyme expression. Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in the caput has a physiological relevance in human epididymis functions.. ...
The generation of single cell sequencing data from human tissues is transforming our understanding of biological mechanisms. This is particularly true for poorly studied organs and tissues that are difficult to obtain. One such tissue is the human male genital duct, the epididymis and vas deferens, which have a pivotal role in sperm maturation and hence maintenance of the species. Most models of epididymis function are based upon other mammals, which show substantial anatomic and functional diversity. Here, we construct a single cell atlas of the human proximal epididymis, which reveals detailed molecular characterization of both common and rare cell types, and hence may advance our understanding of mechanisms of male fertility.. The key functions of the epididymis are performed by the cells lining the lumen of the duct, which maintain a low pH environment necessary for sperm quiescence. These cells also secrete a wide spectrum of proteins, peptides, and RNAs that provide the necessary cues for ...
In our previous studies, we showed that a finasteride-induced DHT deficiency may cause changes in the morphology of the seminiferous epithelium without any morphological alteration of the epididymis. In this study, we demonstrated the constitutive immunoexpression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of Wistar rats treated with finasteride for 28 days (the duration of two cycles of the seminiferous epithelium) and 56 days (the duration of one spermatogenesis). We noted that a 56-day finasteride treatment mainly caused a decrease in the level of circulating DHT, as well as a statistically insignificant decrease in the level of T. The hormone deficiency also led to a change in the iNOS immnoexpression in the testis and epididymis of the finasteride-treated rats. In vitro, DHT did not modify NO production by the epithelial cells of the caput epididymis even when stimulated with LPS and IFNγ, but it did give rise to an increase in NO production by the epithelial ...
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E: epididymis (CA: caput, CO: corpus; CU: cauda). T: testis Other human epididymis _ specific gene products (Table 3) HUMAN EPIDIDYMAL cDNA FAMILIES HE1-HE6 Using a strategy of differential secreening of human epididymal cDNA libraries, a set of six major secretory proteins of human epididymal epithelial cells, named HE1-HE6, were identified (Kirchhoff et al, 1990). With the exception of HE5, the others are novel (human) gene products, not previously reported in animal studies. A brief description of HE1, HE2, HE3, HE4, HE5, and HE6 molecular characterization is presented in the following paragraphs. HE1: HE1 is a major secretory glycoprotein detected as a ~ 20 KDa protein, present within the epithelium and lumen of the corpus epididymis, and accumulated in the lumen of cauda epididymis and vas deferens. The mRNA encoding HE1 was found to be the most abundant gene product obtained using the strategy of differential screening. HE1 is well conserved among mammals (in chimpanzee, named EPI-1 (Perry ...
www.ivfbaby.com Percutaneous Epididymal Sperm Aspiration or PESA. A needle is passed through the scrotal skin and into the epididymis in order to aspirate sperm. Because the epididymal tubule is very delicate and convoluted, the yield with a needle is typically small and usually only sufficient for a single cycle of IVF-ICSI performed on the same day as the PESA. In male infertility occasionally sperm may not be reliable retrieved at all. PESA can be used for men with congenital absence of the vas and in lieu of vasectomy reversal. This procedure involves insertion of a small needle, under local anesthesia, directly into the epididymis for aspiration of a fewer number of sperm than would be necessary for fertilization by conventional IVF. However, in most cases there are more than enough sperm to fertilize all oocytes by ICSI. With newer cryopreservation techniques, there may even be sufficient numbers of sperm for freezing so that additional ICSI procedures could be performed in the future ...
Because our data suggest that sRNAs in mature sperm could have originated at multiple locations throughout the reproductive tract, we assessed the effect of paternal diet on sRNAs in the testis (n = 9 pairs), caput epididymis (n = 6), and cauda epididymis (n = 5) (fig. S5). Two prominent dietary effects on the cauda sperm RNA repertoire-increased abundance of glycine tRFs and decreased abundance of let-7-were recapitulated in the testis and epididymis but not in the liver, muscle, or blood (table S1). Thus, tissues throughout the male reproductive tract, including mature sperm, exhibit consistent changes in glycine tRFs and let-7 in response to the low-protein diet, suggesting that similar diet-responsive pathways are present throughout the tract and providing technical replication of the fundamental epigenomic changes wrought by the low-protein diet.. Our finding of robust tRNA cleavage in the epididymis but not the testis raises the possibility that the abundant tRFs in the cauda sperm might ...
immune Uncategorized PA-824, Rabbit Polyclonal to C-RAF (phospho-Thr269). The blood-epididymis barrier (BEB) is formed by epithelial tight junctions mediating selective permeability from the PA-824 epididymal epithelium. the paracellular permeability had been examined by two strategies TER and FITC-Dextran-based tracer diffusion assays. Both assays soon add up to related outcomes indicating a time-dependent disruption from the BEB differentially for the three TGF? isoforms (TGF?3>TGF?1>TGF?2) inside a TGF?-recetor-1 kinase- and Smad-dependent way. The small junction proteins claudin-1 was discovered to be decreased by the procedure with TGF?s whereas occludin had not PA-824 been affected. Epididymal epithelial cells are mainly attentive to TGF?s PA-824 through the basolateral side recommending that TGF? may impact for the epididymal epithelium through the stroma cell tradition versions the knockdown of 1 of the claudins (1 -3 -4 or -7) led to dramatically reduced transepithelial electrical level ...
The epididymis plays a significant role as a quality control organ for long-term sperm storage, maturation, and fertilizing ability and perform filtration function to eliminate abnormal or residual spermatozoa by phagocytosis. However, the role of autophagy in spermiophagy during sperm storage in turtle epididymis still needs to be studied. In this study, we reported in vivo spermiophagy via the cellular evidence of lysosome engulfment and autophagy within the principal cells during sperm storage in the turtle epididymis. Using immunofluorescence, Lysosome associated membrane protein-1 (LAMP1) and microtubule-associate protein light chain 3 (LC3) showed strong immunosignals within the apical cytoplasm of epididymal epithelia during hibernation than non-hibernation. Co-immunolabeling of LAMP1 and LC3 was strong around the phagocytosed spermatozoa in the epididymal epithelia and protein signaling of LAMP1 and LC3 was confirmed by western blotting. During hibernation, ultrastructure showed
The epididymis (plural, epididymides) is a tightly coiled mass of thin tubes that carries sperm from the testes to the ductus deferens in the male reproductive system. Sperm matures as it pa
Objective: To evaluate the effect of the levels of IGF-Ⅰin the epididymis and the expression of IGF-Ⅰ in the testis of adult male rat after the administration of cyclophosphamide.Methods: Ninety-six male adult rats(8 weeks age)were divided into 6 groups.The doses given to the rats of the groups 1 to 5 were 10,20,40,80 and 100 mg/(kg·d),respectively.The remaining group was served as control.All those rats were sacrificed and IGF-I were quantitatively determined by ELISA techniques 2 and 4 weeks after the administration of the drug(by gastric fudge).Immunohistochemical SP technique was used to examine expression of IGF-I in rat testis. Results: The levels of cell factors(IGF-I)in the epididymis of the rats were gradually reduced with the increasing time and dose after administration of the drug.In the mean time the expression of IGF-I in the tissues of the testis of those rats were also gradually reduced.Conclusion: In the time of oligozoospermia/azoospermia induced by the administration of
Read Angiotensin II receptors: Localization of type I and type II in rat epididymides of different developmental stages, The Journal of Membrane Biology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
The epididymis is the organ with an elongated shape. It is attached to the near end of the testes, and is measuring for about 5.5 meters long, although its length could not be recognized due to its coiled feature. This part of the male reproductive organ keeps the sperm cells safe until its final stage of maturation- that is, the maturation of the tail.. Its head is known for its expanded portion that is clearly visible, and its body slowly fades out as it advances to the mid-section. The tail of the epididymis continues from the beginning of the ductus deferens. These sections are responsible for the storage of the maturing sperm cells until they are ready for ejaculation.. Normally, it takes 8 weeks for the male body to make mature sperm cells. ...
Purified Bovine Epididymis Lysate, Total Protein from Creative Biomart. Bovine Epididymis Lysate, Total Protein can be used for research.
Epididymis - What can cause the epididymis to be hard? Could be cyst. But it will not be hard Any testicular mass needs to be evaluated by trained professional (physician) to make sure is not a testicular tumor must see your doctor.
Purpose Spermatozoa undergo critical changes in structure and function during the epididymal transit. Our previous studies in the domestic cat demonstrated that incidence of cenexin-a key protein...
Every attempt was made to provide correct information and labelling, however any liability for eventual errors or incompleteness is rejected! ...
I am a 35 years old male. I got a lump in my right testicle operated last year. I am again developing a lump in the left testicle. |b|My epididymis is swelling, is hard and pains when pressed|/b|. My wife has a problem of white discharge from vagina. What do I need to do now?
Question - Infection on the epididymis. On antibiotics. Pus cells in urine. What is wrong?. Ask a Doctor about diagnosis, treatment and medication for Urinary tract infection, Ask a Urologist
Sperm from wild type and SP hyh (hyh) mice were collected from the cauda epididymidis, incubated under capacitation conditions for 1 h and stimulated with buffer (control), 10 µM progesterone (Pg) or 10 µM A23187 (A23187) for 15 min at 37°C.. PLoS ONE Alerts: New Articles. ...
The epididymis is at the back of the testicle, so i presume you indicate the lump is the head of the epididymis that is inflamed, it has a head a body and a tail that runs to almost 19 foot lengthy.. I had this two years in the past, i had it for approx 5 months in total one month serious and then 4 months on and off, and then a single day it just vanished and now i really feel absolutely nothing there, a whole lot of those antibiotics are undesirable information my friend, u dont need to have them for a simple non critical infection like this, people physicians only prescribe them due to the fact theyr striving to vindicate the bill their going to send you in a number of days, its like employing a sledgehammer to destroy an ant, also the epididymis is a quite intricate, tunnel-like spidery canal in which sperm mature and the infection can hide there from the antiobiotics in a crease and stay unchecked by the bodys immune technique for numerous weeks but it ought to ultimately be taken care of ...
Maturing sperm. Coloured freeze-fracture scanning electron micrograph (SEM) of healthy spermatozoa (sperm, pink) in the epididymis (green). Sperm cells are the male sex cells. They are produced in the testes and are responsible for fertilisation of the female ovum (egg). The epididymis is a long convoluted tube connecting the testes to the vas deferens. Here, a cross-section has been taken across two of its coils, making it appear as three separate tubes. Magnification: x300 when printed 10 centimetres wide. - Stock Image C002/0983
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Back in June 2012, I did some heavy lifting one day and that night I felt a sharp pain for a moment in my testicle. The next morning my right Testicle was swollen. I could not see a doctor for three weeks because none where accepting ne
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Bruce, Brendan; La Barbera, Andrew R.; Marsh, Karen (University of Cincinnati. College of Medicine; University of Cincinnati, 2007-09-28) ...
TESA and MESA are two different types of testicular biopsy. There are others too, each characterised as follows: MESA: Sperm aspiration from the epididymis
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Sperm maturation involves an intimate interaction between spermatozoa and the epididymal epithelium. Aspects of this relationship can be examined by co-incubating epididymal spermatozoa with epididymal epithelium in vitro. Plaques of epididymal epithelium from a variety of species (for example rodents, dogs, humans) can be maintained in culture medium supplemented with growth factors and androgens. When co-incubated with these epithelial cultures, immature epididymal spermatozoa undergo maturation changes that lead to the acquisition of progressive motility, zona binding and, in some instances, fertilizing capacity in vitro. The use of such co-culture techniques for the understanding of sperm maturation in vitro and in vivo is reviewed with reference to recent experiments.. ...
Looking for online definition of conical lobules of epididymis in the Medical Dictionary? conical lobules of epididymis explanation free. What is conical lobules of epididymis? Meaning of conical lobules of epididymis medical term. What does conical lobules of epididymis mean?
Here, the protein-coding genes expressed in the epididymis are described and characterized, together with examples of immunohistochemically stained tissue sections that visualize protein expression patterns of proteins that correspond to genes with elevated expression in the epididymis. Transcript profiling and RNA-data analyses based on normal human tissues have been described previously (Fagerberg et al., 2013). Analyses of mRNA expression including over 99% of all human protein-coding genes was performed using deep RNA sequencing of 172 individual samples corresponding to 37 different human normal tissue types. RNA sequencing results of 1 fresh frozen tissues representing normal epididymis was compared to 171 other tissue samples corresponding to 36 tissue types, in order to determine genes with elevated expression in epididymis. A tissue-specific score, defined as the ratio between mRNA levels in epididymis compared to the mRNA levels in all other tissues, was used to divide the genes into ...
Received: 21/Apr/2008, Accepted: 19/Jan/2009 Objective: Carrot (Daucus carota L.) is known to possess antifertility properties in female. However, according to Iranian traditional medicine, it can increase the potency in men. The aim of this study was to investigate the influence of carrot seed extract (CSE) on spermatogenesis, number and motility of sperms in cauda epididyme in male rats. Materials and Methods: Forty adult male rats were randomly divided into 5 groups: control group, groups receiving lowand high doses of CSE, animals that received high-dose of CSE with gentamicin, and a gentamicin only group. After 4 weeks treatment, fasting serum samples were obtained for the sex hormone analysis. Under anesthesia, testis, cauda epididymides and sperm ducts were dissected and sperm count, motility and cauda epididymis sperm reserves (CESR) were determined. Histopathological changes of testis were also studied to assess spermatogenesis. Data analysis was performed using one-way ANOVA followed by Tukey
Following freeze-fracture of the rat epididymis, a population of cells whose apical, but not baso-lateral, plasma membrane contains elongated intramembrane particles was found in the initial segment. From their size, shape and distribution, these cells are assumed to be the so-called apical cells of this segment. Apical cells also contain the enzyme, carbonic anhydrase which, together with the presence of rod-shaped particle on their membranes, permits their classification as mitochondria-rich cells, a specialized cell type found in some transporting epithelia. On the basis of these observations, we suggest that the apical cells may play a role in fluid and/or electrolyte transport in the initial segment of the epididymis. ...
A 31-year-old man with recurrent testicular torsion and infertility was found to have a fusional anomaly of the epididymis on scrotal exploration in which only the head of epididymis was attached to the testis, while the body and tail were completely free. He had bilateral orchidopexy, which relieved pain and recurrent torsion. He was then referred for fertility treatment. Literature search has shown that infertility is more associated with congenital anomalies of the epididymis and not with recurrent torsions ...
The alternative to surgical reversals or reconstruction / repair is sperm retrieval by needle aspiration, and the techniques commonly employed, are PESA (Percutaneous Epididymal Sperm Aspiration) and TSE (Testicular Sperm Extraction). Most men are familiar with their soft and squishies, but know little of the epididymis; sausage-like sacs attached behind each testicle that contain meters of tightly coiled miniscule tubes and canals. In essence, they connect the testicles bilaterally to the vas deferens, which constitute the main pipeline of the males reproductive tract. The epididymis is the subject of controversy, but it can be safely said that they act to accumulate and transport sperm. In the normal male, it takes 6 weeks for sperm to travel their path from genesis in the testicles to ejaculation, and a large part of that time is spent in the epididymis. The controversy though is intriguing. Some specialists believe that the very fine hairs within the epididymis literally stroke the sperm ...
Introduction: Ovarian cancer is one of the most common malignancies in women and the fifth cause of cancer-related deaths in women worldwide. Contrary to the challenges in developing new clinical markers using the conventional methods, recent advances in genomics and proteomics have led to identification of candidate and promising biomarkers for the diagnosis of ovarian cancer. Human epididymis protein 4 (HE4) is such a marker that has recently been reported to correlate with recurrence or progression of epithelial ovarian cancer. The purpose of this study was to measure the expression level of HE4 gene in women with ovarian cancer. Methodology: We evaluated and compared paraffin-embedded tissue samples of 20 ovarian cancer patients with 10 samples from healthy individuals. RNA was initially extracted from the samples and cDNA was synthetized. Gene expression level was then measured using real-time polymerase chain reaction (PCR). Results: Our results demonstrated that HE4 gene expression
Adult male rats were injected with TSAA-291 (16 beta-ethyl-17 beta-hydroxyestr-4-en-3-one), a steroidal antiandrogen, daily for 30 days at two doses, viz., 10.0 and 25.0 mg/kg. The treatment caused a dose-dependent reduction in the weights of testis, epididymis, and other accessory sex glands. In the animals that received the high dose, 50% of the rats showed spermatogenic arrest in about 20% of the seminiferous tubules and Leydig cell morphology was normal. The levels of glycerylphosphorylcholine and sialic acid were significantly reduced in the cauda epididymis of all the treated rats. There was a reduction in the number of motile spermatozoa in the cauda epididymis of rats treated with high dose of the antiandrogen. This was accompanied by a reduced number of females exhibiting spermatozoa in their vaginal smears. A combination treatment of the antiandrogen and androgen appears to be a promising approach for fertility regulation in the male.
We appreciate the opportunity to discuss our paper ( Sutovsky et al., 2001a) and thank Cooper et al. for their respected opinion. Our work provides morphological and biochemical evidence that ubiquitin, a universal proteolytic marker that is also implicated in endocytosis, is found predominantly on the surface of defective spermatozoa during and after, but not prior to, their passage through the epididymis. Since the covalent ligation of ubiquitin serves as a selective, substrate-specific signal for proteolytic degradation ( Laney and Hochstrasser, 1999), we suggested the term epididymal sperm quality control. The presence of ubiquitin in human sperm ( Sutovsky et al., 2001b), seminal plasma ( Lippert et al., 1993) and epididymal epithelium ( Fraile et al., 1996; Santamaria et al., 1993) has been shown previously, and we performed an extensive set of control experiments to test the specificity of our anti-ubiquitin antibodies. Other proteins including clusterin ( Ibrahim et al., 2000) and ...
This study was designed to study the capacitation of caudal spermatozoa in vitro by different levels of heparin, estrogen for in vitro fertilization (IVF) in the Iraqi local sheep. Results of sperm capcitation (massive motility percentage) by applying three levels of heparin (50, 100, 150) IU in relation to breeding season showed no significant differences during breeding season with the three levels, which were (82.23 ± 0.58), While results by applying the higher level of heparin (150) IU out of breeding season showed significantly (P,0.05) more and active motility Which were (62.07 ± 0.62) than the other levels (56.85 ± 0.61). At the same time applications result of three estrogen levels (20, 40, 60) mg on sperm capcitation showed Positive relationship between concentrations and (massive motility percentage), which showed the highest concentration gave the best results during and out of breeding season (87.20 ± 0.60) and (65.86 ± 0.62) respectively. with significant differences (P,0.05) ...
The epididymis is tube-like cavity located around the scrotum, a part of the male reproductive system. The sperm moves into and collects in the epididymis before it moves further into the vas deferens.. Epididymal cysts, commonly called scrotal cysts refer to fluid-filled sacs that occur in the tube-like epididymis. In most cases, the cyst is a benign one. They do not cause any pain in the patient and only cause some mild discomfort. They are also not associated to cancer in any way. These cysts occur at the head of the epididymis, which is just above the testicles. They can even be found by self-inspection, or the doctor may find them through a simple physical inspection. However, these cysts or lumps are not to be compared with cancer lumps, which occur within, rather than on, the testicles.. The most common and viable treatments in metro cities like Mumbai for scrotal cysts is the scrotal cyst removal surgery. Other forms of scrotal cyst removal treatment in Mumbai include using a needle to ...
BioAssay record AID 36841 submitted by ChEMBL: Inhibition of the enzyme alpha-L-fucosidase from bovine epididymis was determined at 1 mM concentration of the compound; No inhibition.
Bekijk Stockfoto van Crosssection Through The Wall Of The Epididymis Showing Long Microvilli On The Surface Of The Pseudostratified Epithelium And The Underlying Layer Of Smooth Muscle. Ga voor hoogwaardige fotos met een hoge resolutie naar Getty Images.
Histological comparison of epididymides of 6-mo-old MMTV-VEGF transgenic and WT control mice (A-H), and localization of expression of the VEGF transgene and
Expression of MAPK6 (ERK3, HsT17250, p97MAPK, PRKM6) in epididymis tissue. Antibody staining with HPA030262 and CAB005184 in immunohistochemistry.
0V5J4ZZ is a billable procedure code used to indicate the performance of destruction of right epididymis, percutaneous endoscopic approach. Code valid for the year 2020
DATTA, Uttam; BANDOPADHYAY, Soumendra Kumar y HEMBRAM, Manik Lal. Morphological Study of the Cytoplasmic Droplets as an Index of Sperm Maturation in Black Bengal Buck (Capra hircus). Int. J. Morphol. [online]. 2010, vol.28, n.1, pp.327-332. ISSN 0717-9502. http://dx.doi.org/10.4067/S0717-95022010000100048.. Location of the cytoplasmic droplets (CD) and their dimensions varied significantly (p,0.01) when sperm cells traverse through the regions of caput, corpus and cauda epididymis and vasdeferens respectively. The gradual diminution in the morphology of CD between the epididymal regions were related significantly (p,0.01, p,0.05). Caudal shift of the CD, along with regression in size and finally their exclusion from the sperm cells reflected one of the most important events in the maturation process of male gametes in Black Bengal buck.. Palabras clave : Black Bengal buck; epididymis; spermatozoa; cytoplasmic droplets. ...
TY - JOUR. T1 - Human epididymis protein 4 (HE4) plays a key role in ovarian cancer cell adhesion and motility. AU - Lu, Renquan. AU - Sun, Xinghui. AU - Xiao, Ran. AU - Zhou, Lei. AU - Gao, Xiang. AU - Guo, Lin. PY - 2012/3/9. Y1 - 2012/3/9. N2 - Human epididymis protein 4 (HE4) is a novel and specific biomarker for epithelial ovarian cancer (EOC). We previously demonstrated that serum HE4 levels were significantly elevated in the majority of EOC patients but not in subjects with benign disease or healthy controls. However, the precise mechanism of HE4 protein function is unknown. In this study, we generated HE4-overexpressing SKOV3 cells and found that stably transduced cells promoted cell adhesion and migration. Knockdown of HE4 expression was achieved by stable transfection of SKOV3 cells with a construct encoding a short hairpin DNA directed against the HE4 gene. Correspondingly, the proliferation and spreading ability of HE4-expressed cells were inhibited by HE4 suppression. ...
The HE6 receptor is expressed at high levels within the efferent ductules and the initial segment of the epididymis (32, 34), regions of the reproductive tract which are well characterized as being responsible for the absorption of ,90% of the fluid produced by the testis (4). The concentration of sperm delivered to the ductus epididymis is determined by the net fluid reabsorption across the efferent duct epithelium (4, 20). Considering the abnormal accumulation of spermatozoa within the efferent ductules observed in HE6 knockout mice, a role for this receptor in the regulation of fluid balance is suggested.. Fluid reabsorption within the efferent ductules is primarily a passive process that occurs in parallel with the establishment of an Na+ gradient across the nonciliated cells of the epithelium (17). The hydration of CO2 by carbonic anhydrase II within the nonciliated cells results in the production of H+ and HCO3−. H+ is exchanged for luminal Na+ by the apically located sodium-hydrogen ...
Ruptures. Actually, the technical term for this phenomenon is a blowout. According to Campbell s Urology (a textbook for urology students and doctors) The brunt of pressure-induced damage after vasectomy falls on the epididymis and efferent ductules . It is likely that, in time, all vasectomized men develop blowouts in either the epididymis or efferent ducts. This rupturing can occur spontaneously at any time following vasectomy, and often when the epididymis is under pressure, such as when a man is ejaculating. It doesn t feel good.. Autoimmune Responses. But that s not all. When the rupturing occurs, sperm cells enter the blood stream, where they were not naturally intended to be. As a matter of fact, nature makes a very specific point of keeping sperm cells out of the blood stream, because sperm cells have very strong enzymes on their surfaces and only half a DNA strand. What does the body think is happening? The immune system is sent on full alert to fight off a perceived infection of ...
A spermatocele or epididymal cyst is a sperm filled cyst in the epididymis at the top end of the testicle. The epididymis consists of hundreds of tiny tubules that collect sperm from the testes, and join up to lead into the vas deferens, which takes the sperm to the seminal vesicle (sperm storage sac) and penis. Cyst formation may follow an injury to the testicle or a vasectomy, but often appears for no apparent reason.. A lump is felt at the top of the testicle, but separate from the testicle. It is usually painless, but may become painful if injured or infected. Bleeding into the cyst after an injury may cause a sudden increase in size and pain.. It is usually a clinical diagnosis, but an ultrasound scan can confirm the diagnosis if there is any concern.. No treatment is necessary unless the patient finds the cyst painful, uncomfortable or worrying, when it can be drained or removed.. ...
The mature spermatozoa are released from the protective Sertoli cells into the lumen of the seminiferous tubule and a process called spermiation then takes place, which removes the remaining unnecessary cytoplasm and organelles. The resulting spermatozoa are now mature but lack motility, rendering them sterile. The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells with the aid of peristaltic contraction. Whilst in the epididymis they acquire motility and become capable of fertilisation. However, transport of the mature spermatozoa through the remainder of the male reproductive system is achieved via muscle contraction rather than the spermatozoons recently acquired motility. ...
Infertility is a very sensitive topic for various couples. Seeing other couples having babies without any hassle and youre trying so hard to conceive can be very disturbing and heart breaking. In recent times, several surgical procedures have been introduced to retrieve sperm. Lets have a look at surgical sperm collection (SSC) procedure in this post. What is SSR or Surgical sperm retrieval? SSR or surgical sperm retrieval has been developed to collect sperms from testis or epididymis. This treatment has helped million of couples to conceive genetic baby even when there is no ejaculation of sperm. In addition to this, its very simple. Percutaneous Epdidymal Sperm Aspiration (PESA) In this procedure sperm is collected from epididymis with the help of small needle (no cuts are involved). After sample collection, it is examined under microscope to check the presence of sperm. If PESA is not successful, then TESA procedure is…. ...
The present study was designed to investigate the effect of a proteinaceous dietary supplement, fishmeal, on gossypolinduced spermatotoxicity. Twenty-five adult male Wistar rats, averaging 205 g b.w., were randomly sorted into four experimental groups (I-IV) of 5 animals each, and a control group. Crude cottonseed oil was administered orally to each animal in groups I-IV at a rate that provided 14 mg/kg/d free gossypol; in addition, 3 g/d, 7 g/d, and 10 g/d of fishmeal was provided as meal supplement to each animal in groups I, II and III respectively. The control group received rat pellets and water freely. At the end of the 53-day treatment period, all animals were placed under chloroform anaesthesia; the caudal epididymides were removed, minced and placed in Hams F10 solution for the evaluation of sperm count and motility. The testes were also processed for histological studies using the eosin and haematoxylin (H & E) method. Our findings revealed a dose-dependent inhibition of ...
The ductus deferens (plural: ductus deferentes) forms part of the male internal genitalia where it transports sperm from the epididymis to the ejaculatory duct. In modern anatomic nomenclature, it is no longer referred to as the vas deferens (plu...
INTRODUCTION. In 1896 Krukenberg (1) described an unusual form of an ovarian metastasis by a gastrointestinal cancer. The analogue in male, a metastasis to the testis or epididymis by a primitive gastric cancer is extremely rare. We report an unusual metastasis to the testis and epididymis, which has all criteria to be called Krukenberg-tumor.. CASE REPORT. W.A., a 68 years old patient, was submitted to total gastrectomy in 1994. Histologically it was described a diffuse, poorly differentiated gastric adenocarcinoma with multiple lymph node metastases along the greater and lesser gastric curvature and an isolated lymph node metastasis in the splenic hilum (TNM stage: pT3 GIII N+ M1).. One year later the patient developed a light painful swelling of the right hemiscrotum and groin. The palpation revealed a painful mandarine-like mass conglobated in the right testis and epididymis, which seemed to be connected with a further mass, about as big as a chestnut, at the external inguinal-ring. Multiple ...
Hellman, B; Thelander, L; and Taljedal, I, Postnatal growth of the epididymal adipose tissue in yellow obese mice. (1963). Subject Strain Bibliography 1963. 1156 ...
Efferent ducts: | | | |Efferent ducts| | | | | ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled.
Glycosidase activities in principal cells, basal cells, fibroblasts and spermatozoa isolated from the rat epididymis.: The activity levels of beta-N-acetylgluco
5.3.1 Male Reproductive Tract (Interactive Diagram) -What are the functions of the male reproductive tract? -What are the functional components of the male reproductive tract? -What are the differences between the secretions of the seminal vesicles and the prostate? -What is the usual composition of semen ...
Male sterilization or vasectomy is a simple procedure in which a piece of each vas deferens is cut out just above the epididymis and the cut ends are tied. This procedure is normally done under local anesthetic in the doctors office. Because the sperm stored in the epididymis can no longer flow through the vas deferens, the mans ejaculate does not contain sperm. ...
Sorry to revive this thread.. I have been having some pain in my left testicle for a while now, and I think the epidimymis might be enlarged. I have also been getting more serious with the PE, and getting results. I edge a lot during my PE sessions. I think the pain is either from my balls getting knocked around and squished in my pants when I exercise, really bad blue balls from the gains Ive been getting, or epididymitis.. My question is to you more experienced PEers, who have gotten gains and edge a lot: Does a lot of PE and edging predispose you to epididymitis? Is it something I need to worry about. Is it possible for the epididymis to grow without being infected/inflamed, and become a healthier, happier epididymis from PE?. Thanks everybody ...
Top 10 tissues for 1283_at (Homo sapiens, Affymetrix Probeset): epididymal corpus, epidermal melanocyte, conjunctival epithelium cell (sp.), retina, conjunctival mucosa cell, epididymal region, epididymal cauda, transverse colon, neutrophil granulocyte, caecum (cecum)
Emily Aulicino is one of the most dynamic people I know. Her energy and enthusiasm has helped make Oregon the largest member per capita region in all of ISOGG. Emilys educator background is apparent and complimentary to her speaking engagements which create a presentation that is easy-to-understand for any novice. Her reputation has made her an immensely popular speaker throughout the Pacific Northwest which has resulted in nationwide requests. Emily is a proven leader who welcomes a challenge. She manages many people and projects with skill and ability that can only be innate. I have the utmost confidence that Emily will excel at any task presented to her and I look forward to many more years working with her ...
Emily Aulicino is one of the most dynamic people I know. Her energy and enthusiasm has helped make Oregon the largest member per capita region in all of ISOGG. Emilys educator background is apparent and complimentary to her speaking engagements which create a presentation that is easy-to-understand for any novice. Her reputation has made her an immensely popular speaker throughout the Pacific Northwest which has resulted in nationwide requests. Emily is a proven leader who welcomes a challenge. She manages many people and projects with skill and ability that can only be innate. I have the utmost confidence that Emily will excel at any task presented to her and I look forward to many more years working with her ...
Possible surgery. Sadly, chronic epididymitis present for that long, is not likely to go away. Many men respond for varying periods of time to antibiotic treatment. Some will get temporary improvement to a spermatic cord block. The last resort would be surgical epididymectomy. Although this may diminish fertility, it shouldnt affect other testicular function. (testosterone ...
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The organs of the male reproductive system are specialized for the following functions: To produce, maintain and transport sperm (the male reproductive
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Bennett, D and Dunn, L C., Studies of effects of t-alleles in the house mouse on spermatozoa. I. Male sterility effects. (1967). Subject Strain Bibliography 1967. 576 ...
my epididymis seems to be swelled up on my right side...my scrotum has recently been swelled up on the right side...can i assume that the inflammation probably stems from the fact that i was a little rough when i was checking myself for cancer?. Reply Follow This Thread Stop Following This Thread Flag this Discussion ...
Epididymitis is a swelling and redness of the small coiled tube (epididymis) which sperm pass. This tube is at the back of each testicle. The swelling can be in one or both testicles. (English) Colour ...
The testes are located within the scrotum, with the epididymis situated on the posterolateral aspect of each testicle. Commonly, the left testicle lies lower than the right.
This activity includes a video which shows GPs how to perform a male genital examination. Topics covered include measurement of testis size using an orchidometer, examination of the epididymis and vas deferens, and how to identify a varicocoele.. Enrol in course or Go to course. ...
Principal Investigator:OKAMURA Naomichi, Project Period (FY):1993 - 1994, Research Category:Grant-in-Aid for international Scientific Research, Section:Joint Research
An alpha-glucosidase test can reveal a secretory dysfunction of the epididymis and reduced quality of the semen caused by this disorder.
Doug Walters & Associates Just before Christmas, I had an operation to remove my epididymis; this was the culmination of a TWO YEAR journey in terms of this particular medical problem, during which I experienced the best and worst of the National Health System, which was p...
J:244916 Zhao F, Franco HL, Rodriguez KF, Brown PR, Tsai MJ, Tsai SY, Yao HH, Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017 Aug 18;357(6352):717-720 ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... In the male the duct persists, and forms the tube of the epididymis, the vas deferens and the ejaculatory duct, while the ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... which is sometimes found in front of the spermatic cord above the head of the epididymis. In the female the mesonephric bodies ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, ...
While in the epididymis the spermatozoa gain motility and become capable of fertilization. However, transport of the mature ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells with the aid of ... The initial stages occur within the testes and progress to the epididymis where the developing gametes mature and are stored ... Maturation occurs in the epididymis. The location [Testes/Scrotum] is specifically important as the process of spermatogenesis ...
Joseph A, Shur BD, Hess RA (2011). "Estrogen, efferent ductules, and the epididymis". Biol Reprod. 84 (2): 207-217. doi:10.1095 ... and lack of spermatozoa in the epididymis has been observed in conjunction with defects in MCC development. "Geminin coiled- ...
"Torsion of the Appendices and Epididymis". Medscape. Updated: Oct 20, 2016. Citing: Nason, Gregory J; Tareen, Farhan; ...
Whilst in the epididymis, they acquire motility. However, transport of the mature spermatozoa through the remainder of the male ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells, with the aid of ...
Backpressure from blockage of the vas deferens causes a rupture in the epididymis, called an "epididymal blowout", in 50% of ... When pain in the epididymides is the primary symptom, post-vasectomy pain syndrome is often described as congestive ... There is a noticeable enlargement of the epididymides in vasectomized men. This is probably due to increased backpressure ... One study using ultrasound found that the epididymides of patients suffering from post-vasectomy pain syndrome were enlarged ...
A second tube, the ductulus aberrans superior, occurs in the head of the epididymis; it is connected with the rete testis. This ... Occasionally it is found unconnected with the epididymis. ... connected with the lower part of the canal of the epididymis, ...
Cells of the epididymis also have ACVR2A receptors present. ACVR2B receptors were found to be localized in the rete testis. The ...
Pseudostratified columnar epithelia with stereocilia are located in the epididymis. Stereocilia of the epididymis are not cilia ...
... it transports sperm from the epididymis in anticipation of ejaculation. In humans, the vas deferens routes up from the testicle ...
The epoophoron is a homologue to the epididymis in the male. While the epoophoron is located in the lateral portion of the ...
Type B is further subdivided into: Type B1: The supernumerary testicle has its own epididymis but is not connected to a vas ... Type A is further subdivided into: Type A1: Complete duplication of the testicle, epididymis and vas deferens. Type A2: The ... Type A3: The supernumerary testicle shares the epididymis and the vas deferens of the other testicles. Type B: The ... Type 3: The supernumerary testicle has its own epididymis and shares a vas deferens. Type 4: Complete duplication of the ...
... though palpation may reveal an indurated epididymis. A scrotal ultrasound may reveal problems with the epididymis, but such an ... In the chronic version, the patient may have painful point tenderness but may or may not have an irregular epididymis upon ... Epididymitis is a medical condition characterized by inflammation of the epididymis, a curved structure at the back of the ... The bacteria in the urethra back-track through the urinary and reproductive structures to the epididymis. In rare circumstances ...
The epididymis coil on the testes connects to the vas deferens. The vas deferens crosses over the ureter and enters the urethra ...
The higher levels of these hormones enable spermatogenesis in the seminiferous tubules and sperm maturation in the epididymis. ... "Secretion and role of androgen-binding proteins in the testis and epididymis". Journal of Reproduction and Fertility. ...
The accumulation of sperm increases pressure in the vas deferens and epididymis. The entry of the sperm into the scrotum can ... Much fluid content is absorbed by membranes in the epididymis, and much solid content is broken down by the responding ... Sperm is matured in the epididymis for about a month before leaving the testicles. After vasectomy, the membranes must increase ... This method may avoid testicular pain resulting from increased back-pressure in the epididymis. Studies suggest that this ...
The scrotum contains the external spermatic fascia, testes, epididymis, and ductus deferens. It is a distention of the perineum ... Appendix of epididymidis Cavity of tunical albuginea Cremaster muscle Dartos Ductus Deferens Efferent ductules Epididymis ...
... fetal lung and epididymis. In terms of health state, CFAP299 has a decreased expression level in glioma, germ cell tumors and ...
In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter. Spermatic cord Artery to ...
Care is taken not to injure testicular vessels, epididymis or ductus deferens. The edge of the hydrocele sac is oversewn for ... and the tunica vaginalis is the tissue that remains overlying the testis and the epididymis. Congenital hydrocele results when ...
An epididymal cyst is a cyst of the epididymis containing serous liquid. They are difficult to differentiate from a ...
The epididymides hold the sperm as the testes retreat. Mating is usually initiated in April, with the female then using the ...
Sperm are abundant in the epididymides throughout the year. Just before daylength begins to increase in December, conception ...
Hejmej A, Bilinska B (June 2018). "The effects of flutamide on cell-cell junctions in the testis, epididymis, and prostate". ...
Mital, Payal; Hinton, Barry T.; Dufour, Jannette M. (2011-05-01). "The blood-testis and blood-epididymis barriers are more than ...
The kidney is the most frequently affected urogenital organ, followed in men by the epididymis. Testicular sarcoidosis can ... Since it causes occlusion and fibrosis of the ductus epididymis, fertility may be affected. On ultrasound, the hypoechogenicity ... as well as the involvement of the epididymis or vas deferens and bilateral testicular involvement. If the malignant diagnosis ...
There is significant expression in the brain, bladder, epididymis, and the helper T cell. Therefore, there is statistically ...
... protein expression has been detected in the cytoplasm of Leydig cells and in epididymis cells of the male testis and is ... FAM71F2 is highly expressed in reproductive structures, such as the testis, epididymis, uterus and ovaries. There is some ...
The bacterium causes severe inflammation of the epididymis, with formation of spermatocoeles and fibrinous adhesions. This ...
Epididymis secretory sperm binding proteinImported. ,p>Information which has been imported from another database using ... tr,A0A384MTX4,A0A384MTX4_HUMAN Epididymis secretory sperm binding protein OS=Homo sapiens OX=9606 PE=2 SV=1 ...
b,My epididymis is swelling, is hard and pains when pressed,/b,. My wife has a problem of white discharge from vagina. What do ... Why does my epididymis pain when pressed?. Answered by: Prof B Krishna Rau , Professor and Head of Dept. of Surgery,. Sri ... My epididymis is swelling, is hard and pains when pressed. My wife has a problem of white discharge from vagina. What do I need ... Home » Frequently asked Questions on Health » Why does my epididymis pain when pressed? ...
What can cause the epididymis to be hard? Could be cyst. But it will not be hard Any testicular mass needs to be evaluated by ... Epididymis: The epididymis is the confluence of sperm tubes at the base of the testicle. It should not be hard or tender. If ... Cyst from epididymis: Epididymis is part of the conducting system , and in situated one on either side just above and mainly ... Do you mean the head part of epididymis or really in your head? If its the head of epididymis, you would not feel anything at ...
Epididymis Domestic cat Sperm maturation Centrosome Motility Epididymosomes This is a preview of subscription content, log in ... Epididymides were dissected from adult cat testes to assess the presence and localization of cenexin in testicular tissues and ... Zhen W, Li P, He B, Guo J, Zhang Y-L. The novel epididymis-specific beta-galactosidase-like gene Glb1l4 is essential in ... Segmental expression of the bradykinin type 2 receptor in rat efferent ducts and epididymis and its role in the regulation of ...
In vitro, DHT did not modify NO production by the epithelial cells of the caput epididymis even when stimulated with LPS and ... 41] Shayu, D. and Rao, A.J. Expression of functional aromatase in the epididymis: role of androgens and LH in modulation of ... 27] Kolasa, A., Marchlewicz, M., Wenda-Różewicka, L. and Wiszniewska, B. Morphology of the testis and the epididymis in rats ... The expression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of rats with a dihydrotestosterone (DHT) ...
Bovine Epididymis Lysate, Total Protein can be used for research. ... Purified Bovine Epididymis Lysate, Total Protein from Creative ... Bovine Epididymis Lysate, Total Protein. Download Datasheet See All Epididymis Total Protein Products. Bring this labeled ... Epididymis-639B. Product Overview:. Bovine Epididymis Total Protein (protein lysate) is isolated from freshly harvested tissues ...
Results: The levels of cell factors(IGF-I)in the epididymis of the rats were gradually reduced with the increasing time and ... To evaluate the effect of the levels of IGF-Ⅰin the epididymis and the expression of IGF-Ⅰ in the testis of adult male rat ... Objective: To evaluate the effect of the levels of IGF-Ⅰin the epididymis and the expression of IGF-Ⅰ in the testis of adult ... Results: The levels of cell factors(IGF-I)in the epididymis of the rats were gradually reduced with the increasing time and ...
After the can you get testicular epididymis from male enhancement pills Wholesale book, can you get testicular epididymis from ... If you want to donate it, Chu can you get testicular epididymis from male enhancement pills Is Your Best Choice why do i have ... Find Best) Boosted Board Alternative Can You Get Testicular Epididymis From Male Enhancement Pills - Opec.go.th. 2021-02-19 By ... Now my Genuine can you get testicular epididymis from male enhancement pills wife is getting angry, even if I am not, I will ...
Localization of type I and type II in rat epididymides of different developmental stages, The Journal of Membrane Biology" on ... and AT2 receptors observed in the fully mature rat epididymis was much more intense than that observed in the epididymides of ... Angiotensin II receptors: Localization of type I and type II in rat epididymides of different developmental stages. Leung, P.; ... Angiotensin II receptors: Localization of type I and type II in rat epididymides of different... Leung, P.; Chan, H.; Fu, L.; ...
However, the role of autophagy in spermiophagy during sperm storage in turtle epididymis still needs to be studied. In this ... spermiophagy occurs by lysosomal engulfment and autophagic activity within the principal cells of the turtle epididymis during ... The epididymis plays a significant role as a quality control organ for long-term sperm storage, maturation, and fertilizing ... cellular evidence of lysosome engulfment and autophagy within the principal cells during sperm storage in the turtle epididymis ...
When I did see the doctor he claimed it was an infection of the epididymis. I took the medication that he gave me for 7 days. ... The pain seems to be where the testicle meets the epididymis and then can be through a vein in my inner thigh. Any help would ... Is it an infection of the epididymis, or is it something else? ... Is it an infection of the epididymis, or is it something else? ... Is it an infection of the epididymis, or is it something else?. ...
Infection on the epididymis. On antibiotics. Pus cells in urine. What is wrong?. Ask a Doctor about diagnosis, treatment and ... Recently, I was diagnosed wiith some infection on my testis epididymis. I was given lots of antibiotics like amikacin, pipzo ... Infection on the epididymis. On antibiotics. Pus cells in urine. What is wrong?. ...
The epididymis is the organ with an elongated shape. It is attached to the near end of the testes, and is measuring for about ... The tail of the epididymis continues from the beginning of the ductus deferens. These sections are responsible for the storage ...
... epididymides) is a tightly coiled mass of thin tubes that carries sperm from the testes to the ductus deferens in the male ... The epididymis (plural, epididymides) is a tightly coiled mass of thin tubes that carries sperm from the testes to the ductus ... Stereocilia help the lining of the epididymis to absorb excess fluids from the hollow lumen of the epididymis, along with dead ... which can be stored in the epididymis for up to a month. After a month in the epididymis, sperm begin to expire and are ...
Clear cells: the epididymis ionocyte. Clear cells in the epididymis are known to express high levels of the vacuolar ATPase (V- ... In The Epididymis: From Molecular to Clinical Practice Comprehensive Survey of the Efferent Ducts, the Epididymis and the Vas ... These are normal epididymis tissues and not pathological specimens because none of the epididymides have extension of the ... Principal cells are known to be the majority cell type in the epididymis epithelium and predominate in most epididymis cell ...
Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in ... Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in ... β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological ... β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological ...
E: epididymis (CA: caput, CO: corpus; CU: cauda). T: testis Other human epididymis _ specific gene products (Table 3) HUMAN ... epididymis. Biol Reprod 54: 847-856. [ Links ]. KIRCHHOFF C, PERA I, RUST W, IVELL R (1994) Major human epididymis-specific ... the epididymis or become functional in the female tract. Some of the proteins produced by the epididymis, called sperm ... present within the epithelium and lumen of the corpus epididymis, and accumulated in the lumen of cauda epididymis and vas ...
epididymis. . name=description> ...
B) Schematic of the epididymis. Sperm exiting the testis enter the proximal (caput) epididymis, then proceed distally to the ... caput epididymis (n = 6), and cauda epididymis (n = 5) (fig. S5). Two prominent dietary effects on the cauda sperm RNA ... proximal caput epididymis, and distal cauda epididymis (Fig. 2D and table S2). ... C) tRFs are primarily generated in the epididymis. Northern blots are shown for 5′ ends of tRNA-Gly-GCC or tRNA-Val-CAC on RNA ...
Ligament of epididymis may refer to: Inferior ligament of epididymis Superior ligament of epididymis This disambiguation page ... lists articles associated with the title Ligament of epididymis. If an internal link led you here, you may wish to change the ...
The appendix of the epididymis (or pedunculated hydatid) is a small stalked appendage (sometimes duplicated) on the head of the ... Torsion of Appendix Epididymis Anatomy image:7754 at the SUNY Downstate Medical Center inguinalregion at The Anatomy Lesson by ... epididymis. It is usually regarded as a detached efferent duct. This structure is derived from the Wolffian duct (Mesonephric ...
Epididymis. Adult human testicle with epididymis: A. Head of epididymis, B. Body of epididymis, C. Tail of epididymis, and D. ... The epididymis (/ɛpɪˈdɪdɪmɪs/; plural: epididymides /ɛpɪdɪˈdɪmədiːz/ or /ɛpɪˈdɪdəmɪdiːz/) is a tube that connects a testicle to ... The epididymis can be divided into three main regions: *The head (Latin: caput). The head of the epididymis receives ... Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis. In ...
Epididymis (fi); Epididymis (lt); 정소상체 (ko); vescile (en); البربخ, Epididymis (ar); epididymis (cs); எபிடைமிஸ், விந்தக ... Epididymis (sr); Epididymis, Epididimis (bs); 副睾丸, 睾上体 (ja); Najądrza (pl); epididimoj (eo); Bitestiklar, Epididymis (sv); ... Epididymis (es); Canal épididymaire, Epididyme (fr); Epididymis, Dosjemenik (hr); Эпидидимис (ru); Epididymis (de); Epididimo ( ... Epididymis (tl); 부고환 (ko); epididymis (sco); Najądrze (pl); bitestikkel (nn); bitestikkel (nb); Xaya artımı (az); Придаток ...
Epididymis definition, an elongated organ on the posterior surface of a testis that stores sperm while they mature and ... epididymis. Historical Examples. of epididymis. *. The epididymis referred to above, consists of a mass of coiled tubes and ... epididymis. in Medicine. epididymis. [ĕp′ĭ-dĭd′ə-mĭs]. n. pl. ep•i•did•y•mi•des (-mĭ-dēz′). *A long, narrow, convoluted tube in ... epididymis. epididymis. noun plural -didymides (-dɪˈdɪmɪˌdiːz). *anatomy a convoluted tube situated along the posterior margin ...
A varicocele is a bit like an area of varicose veins around the epididymis. These distended veins slowly enlarge over time, and ... My epididymis is still growing. A varicocele is a bit like an area of varicose veins around the epididymis. These distended ... A varicocele is a bit like an area of varicose veins around the epididymis. These distended veins slowly enlarge over time, and ... I say testicle, but I actually mean the thing that runs along the back of the testicle - is it the epididymis? ...
encoded search term (Testes and Epididymis Anatomy) and Testes and Epididymis Anatomy What to Read Next on Medscape ... this layer invests a slitlike recess between the body of the epididymis and the testis that is called the sinus of epididymis. ... The epididymis is a comma shaped, elongated structure composed of a single, fine tubular structure estimated up to 6 meters ( ... Two vestigial embryonic structures of no known physiologic function are often found on the testis and epididymis, as follows:. ...
Epididymis - Hypospermia. A reduced number of sperm in the epididymis in a male F344/N rat from a subchronic study. ... Epididymis - Hypospermia. Higher magnification of Figure 1. A reduced number of sperm in the epididymis in a male B6C3F1 mouse ... Epididymis - Hypospermia. A reduced number of sperm in the epididymis in a male B6C3F1 mouse from a subchronic study. ... Actions of toxicants on the structure and function of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire B ...
... specimen consisting of a bisected testis and epididymis showing multiple foci of caseating tuberculosis in the epididymis with ... A 1937 surgical resection specimen consisting of a bisected testis and epididymis showing multiple foci of caseating ... A 1937 surgical resection specimen consisting of a bisected testis and epididymis showing multiple foci of caseating ... tuberculosis in the epididymis with a small hydrocoele of the tunica vaginalis. ...
Epididymis, Duct - Atrophy. Decreased diameter of empty ducts in the body and tail of the epididymis in a male F344/N rat from ... Actions of toxicants on the structure and function of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire B ... Androgenic regulation of the structure and functions of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire ... If both epididymides are involved, the diagnosis should be indicated as bilateral and the severity based on the more severely ...
... a rat epididymis tissue section is presented that was labeled with the fluorophore Texas Red conjugated to wheat germ ... Rat Epididymis Tissue Section. In the digital image above, a rat epididymis tissue section is presented that was labeled with ...
Torsion of the appendix testis and appendix epididymis means that this tissue of the testis has twisted and cut off its own ... The appendix epididymis is a small appendage located at the top of the epididymis (tube-shaped structure that connects to the ... Pediatric Torsion of the Appendix Testis and Appendix Epididymis. Torsion of the appendix testis and appendix epididymis occurs ... Pediatric Torsion of the Appendix Testis and Appendix Epididymis Pediatric Torsion of the Appendix Testis and Appendix ...
1: Epididymis. 2: Head of epididymis. 3: Lobules of epididymis. 4: Body of epididymis. 5: Tail of epididymis. 6: Duct of ... The epididymis is part of the human male reproductive system and is present in all male mammals. It is a narrow, tightly-coiled ... The epididymis is one of only two regions of the body to have stereocilia (the inner ear being the other.)[2] ... Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis. ...
The Novel Epididymis Specific Beta Galactosidase Like Gene Glb1l4 Is... Identification of a Transcription Factor, BHLHB8, ... Differences in pKi values in caput and cauda epididymis from immature and adult animals also suggested that the relative amount ... These changes were followed by a progressive increase in rat body weight and in caput and cauda epididymis relative weight. ... We have characterized the expression of α1-adrenoceptor in epididymis from rats in different stages of sexual maturation: 40 ( ...
On the epididymis and its role in the development of the fertile ejaculate.. Turner TT1. ...
What is Appendix epididymis? Meaning of Appendix epididymis medical term. What does Appendix epididymis mean? ... Looking for online definition of Appendix epididymis in the Medical Dictionary? Appendix epididymis explanation free. ... appendix epididymis. a small, piriform body attached to the head of the epididymis that is a remnant of the blind cranial ... Related to Appendix epididymis: Appendix testis. appendix. [ah-pen´diks] (pl. appen´dices, appendixes) (L.) 1. a slender ...
Publications about Experts and Doctors on epididymis in Germany ... Cooper T. The epididymis, cytoplasmic droplets and male ... Yeung C, Breton S, Setiawan I, Xu Y, Lang F, Cooper T. Increased luminal pH in the epididymis of infertile c-ros knockout mice ... Damm O, Cooper T. Maturation of sperm volume regulation in the rat epididymis. Asian J Androl. 2010;12:578-90 pubmed publisher ... Ellerbrock K, Pera I, Hartung S, Ivell R. Gene expression in the dog epididymis: a model for human epididymal function. Int J ...
... , Rachel Mngu-suur K, Hambolu Joseph O, ... The epididymis was observed to be highly convoluted at the cranial aspect of each testis as the catput epididymis, the medial ... The epididymis was composed of tightly packed ducts with the head of the epididymis consisting of the most packed ducts as ... Spermatozoa are known to spend a longer time in the catput epididymis and a shorter period of time in the caudal epididymis as ...
... Adv Exp Med Biol. 1991;286:19-32. doi: ... In all, this circumstantial evidence makes it seem possible that the human epididymis as well as the testis often exists in a ... Further effects of deep body temperature on the epididymis are seen in significantly faster (rabbit) sperm transport through it ... Selective imposition of abdominal temperature on the epididymis alone does not suppress sperm maturation there, and bilaterally ...
Epididymis, Human. Hematoxylin & Eosin. Section. Each. Retrieving. The minimum order for this item is . ...
Home › Q & A › Questions › I had epididymis had surgery.... I had epididymis had surgery had left testicle removed, prior pain ...
Diagnostic Test: Human epididymis protein 4 Human epididymis protein 4 serum level in predicting persistent proteniuria ... Human Epididymis Protein 4 in Women With Severe Preeclampsia / HELLP Syndrome. The safety and scientific validity of this study ... Prognostic Value of Human Epididymis Protein 4 (HE4) for Persistent Proteinuria in Women With Severe Preeclampsia / HELLP ...
Epididymis shares the largest number of genes with testis. KIAA1210 is group enriched in testis, epididymis and seminal vesicle ... Epididymis function. The epididymis is a highly coiled, single tubular structure that connects each testicle to the vas ... Genes shared between the epididymis and other tissues. There are 88 group enriched genes expressed in the epididymis. Group ... Protein expression of genes elevated in epididymis. In-depth analysis of the elevated genes in epididymis using antibody-based ...
epididymis answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android ... epididymis is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please log in or purchase a ... "Epididymis." Tabers Medical Dictionary, 24th ed., F.A. Davis Company, 2021. Tabers Online, www.tabers.com/tabersonline/view/ ... Tabers-Dictionary/740004/all/epididymis. Epididymis. In: Venes DD, ed. Tabers Medical Dictionary. F.A. Davis Company; 2021. ...
Zyagen Labs Mouse CD1 epididymis cDNA is a full-length first strand cDNA synthesized from high quality CD1 Mouse epididymis ... Mouse CD1 epididymis cDNA is a full-length first strand cDNA synthesized from high quality CD1 Mouse epididymis tissue RNA by ...
... of epithelium of the human epididymis, cut at the level of the nuclei. Magnification: x7,000 at 8x10 inches. ... Transmission electron micrograph (TEM) of epithelium of the human epididymis, cut at the level of the nuclei. Magnification: x7 ...
Sometimes I ,b,feel pain in my epididymis,/b, and it becomes hard and little bit swollen. But I feel no pain while urinating ... I am a 23 years old male having problem in my right epididymis. ... Why do I feel pain in my epididymis?. Answered by: Dr Ranjith ... Q: I am a 23 years old male having problem in my right epididymis. Sometimes I feel pain in my epididymis and it becomes hard ... A:Pain on one side of the epididymis can be caused by a variety of conditions. Since your pain is transient and is relieved ...
Ang epididaymis (Ingles: epididymis) ay nakakunekta sa bayag na siyang pinupuntahan ng tamod kapag lumalabas ito mula sa bayag ... Kinuha mula sa "https://tl.wikipedia.org/w/index.php?title=Epididymis&oldid=1512070" ...
  • In vitro, DHT did not modify NO production by the epithelial cells of the caput epididymis even when stimulated with LPS and IFNγ, but it did give rise to an increase in NO production by the epithelial cells of the cauda epididymis without the stimulation. (degruyter.com)
  • We find that the CFTR, which is pivotal in normal epididymis fluid transport, is most abundant in surface epithelial cells in the efferent ducts and in rare clear cells in the caput epididymis, suggesting region-specific functional properties. (life-science-alliance.org)
  • Because of its dominant role in male fertility, we focused on the proximal part of the duct and generated a detailed single-cell atlas of the human caput epididymis, which is described here. (life-science-alliance.org)
  • Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in the caput has a physiological relevance in human epididymis functions. (unipg.it)
  • The epididymis (plural, epididymides) is a tightly coiled mass of thin tubes that carries sperm from the testes to the ductus deferens in the male reproductive system. (anatomy-medicine.com)
  • Sperm matures as it passes through the epididymis so that it is ready to fertilize ova by the time it enters the ductus deferens. (anatomy-medicine.com)
  • The smooth muscle tissue contracts in waves of peristalsis to slowly push the sperm along the length of the epididymis toward the ductus deferens. (anatomy-medicine.com)
  • As sperm is needed for ejaculation, it moves from the epididymis to the ductus deferens and onward into the male reproductive tract. (anatomy-medicine.com)
  • In this study, we demonstrated the constitutive immunoexpression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of Wistar rats treated with finasteride for 28 days (the duration of two cycles of the seminiferous epithelium) and 56 days (the duration of one spermatogenesis). (degruyter.com)
  • We noted that a 56-day finasteride treatment mainly caused a decrease in the level of circulating DHT, as well as a statistically insignificant decrease in the level of T. The hormone deficiency also led to a change in the iNOS immnoexpression in the testis and epididymis of the finasteride-treated rats. (degruyter.com)
  • DHT did not have a statistically significant influence on estradiol production by cultured, LPS- and IFNγ-stimulated epithelial cells from the caput and cauda epididymis. (degruyter.com)
  • In our previous studies, we showed that a finasteride-induced DHT deficiency may cause changes in the morphology of the seminiferous epithelium without any morphological alteration of the epididymis. (degruyter.com)
  • The tubule of the epididymis is made of a pseudostratified columnar epithelium lining surrounded by a layer of connective tissue and smooth muscle. (anatomy-medicine.com)
  • These cues are provided in large part by cells in the epithelium of the epididymis, which secrete a complex mixture of ions, glycoproteins, peptides, and microRNAs ( Belleannee et al, 2012a ) that coordinate sperm maturation along the length of genital ducts. (life-science-alliance.org)
  • Epididymis is part of the conducting system , and in situated one on either side just above and mainly behind each testicle. (healthtap.com)
  • The pain seems to be where the testicle meets the epididymis and then can be through a vein in my inner thigh. (askthedoctor.com)
  • This a normal structure of the male reproductive system ( coiled tube that connect the testes to the vas deferens ), sperm goes through the epididymis. (healthtap.com)
  • Epididymides were dissected from adult cat testes to assess the presence and localization of cenexin in testicular tissues and each epididymal segment (caput, corpus, and cauda) via immunofluorescence, Western blot, and mass spectrometry. (springer.com)
  • Morphological and enzymatic study of membrane-bound vesicles from the lumen of the rat epididymis. (springer.com)
  • Stereocilia help the lining of the epididymis to absorb excess fluids from the hollow lumen of the epididymis, along with dead or defective sperm. (anatomy-medicine.com)
  • Spermatozoa released from the testis are unable to fertilize an egg without a coordinated process of maturation in the lumen of the epididymis. (life-science-alliance.org)
  • Epididymis is an elongated lump between testis and vas deferens , consists of a 15-20 feet long convoluted tubules for sperms to pass and mature (in10-12 days), and it usually hugs / attaches right onto the posterior aspect of testis. (healthtap.com)
  • The epididymis is a crescent-shaped coil of thin tubules located inside the scrotum and posterior to the testis. (anatomy-medicine.com)
  • Starting at the efferent tubules of the testis, the tubule of the epididymis winds over the top of the testis and then down the posterior side. (anatomy-medicine.com)
  • Nicander L, Malmqvist M. Ultrastructural observations suggesting merocrine secretion in the initial segment of the mammalian epididymis. (springer.com)
  • There are others too, each characterised as follows: MESA: Sperm aspiration from the epididymis by means of microsurgery. (institutobernabeu.com)
  • PESA: Percutaneous aspiration from the epididymis. (institutobernabeu.com)
  • The human epididymis does not have an initial segment, rather the efferent ducts (EDs) provide the conduit from the testis to the head of the epididymis (caput) where the key functions of sperm maturation are thought to occur. (life-science-alliance.org)
  • The objectives of the study were to (1) characterize mechanisms involved in transferring key factors-using the cenexin as a marker-between the epididymis and maturing sperm cells and (2) demonstrate the impact of such mechanisms on the acquisition of functional properties by spermatozoa. (springer.com)
  • Evidence has also accumulated, indicating that locally formed angiotensin II from the rat epididymis may play a paracrine and/or autocrine role in regulating epididymal electrolyte and fluid transport. (deepdyve.com)
  • The present finding of the differential patterns of angiotensin II receptor immunoreactivity in three different stages of the rat epididymis may reflect the fine tuning of rat epididymal function by angiotensin II, acting as a paracrine or autocrine agent, during the course of development. (deepdyve.com)
  • Thimon V, Koukoui O, Calvo E, Sullivan R. Region-specific gene expression profiling along the human epididymis. (springer.com)
  • Here, we use single cell RNA-sequencing to construct an atlas of the human proximal epididymis. (life-science-alliance.org)
  • The human epididymis has a pivotal role in male fertility. (life-science-alliance.org)
  • Anatomical observations show that unlike in rodents, where the different functional zones of the epididymis, the initial segment, the caput (head), corpus (body), and cauda (tail) are separated by septa, the human duct has no such clear divisions, making functional analyses even more challenging. (life-science-alliance.org)
  • β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. (unipg.it)
  • Is it an infection of the epididymis, or is it something else? (askthedoctor.com)
  • When I did see the doctor he claimed it was an infection of the epididymis. (askthedoctor.com)
  • The entire mass of the epididymis is actually a single, 20-foot-long (six-meter) tubule that has been coiled upon itself so tightly that the entire mass of the epididymis is only around 1.5 inches (4 cm) long. (anatomy-medicine.com)
  • The smooth muscle of the epididymis pushes the sperm along tubule with slow waves of peristalsis, so that the sperm traverse its entire 20-foot length in about two weeks. (anatomy-medicine.com)
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  • The epididymis can be divided into three major regions: the head, body, and tail. (anatomy-medicine.com)
  • In the present study, specific antipeptide antibodies against the second extracellular loops of angiotensin II type I (AT1) and type II (AT2) receptors were used to localize immunocytochemically these receptors in the rat cauda epididymides of three developmental stages, namely, immature (2-week), early mature (6-week) and fully mature (10-week). (deepdyve.com)
  • When sperm first enters the epididymis from the testis , it is very immature and diluted by a relatively large volume of liquid. (anatomy-medicine.com)
  • After clearing the epididymis with multiple ejaculations, and after about 2 weeks of abstinence spermatozoa have been shown to appear in the urine . (healthtap.com)
  • The epididymis plays a significant role as a quality control organ for long-term sperm storage, maturation, and fertilizing ability and perform filtration function to eliminate abnormal or residual spermatozoa by phagocytosis. (aging-us.com)
  • While the immunostaining for both AT1 and AT2 receptors in the younger rat epididymides appeared to be distributed in both basal and apical regions, the immunostaining in the fully mature epididymis was predominantly localized in the basal region. (deepdyve.com)
  • However, the role of autophagy in spermiophagy during sperm storage in turtle epididymis still needs to be studied. (aging-us.com)
  • Why does my epididymis pain when pressed? (ndtv.com)
  • Home » Frequently asked Questions on Health » Why does my epididymis pain when pressed? (ndtv.com)
  • I've had chronic epididymis pain for years now. (healthtap.com)
  • Is it normal to be able to see your own epididymis? (healthtap.com)
  • Is it normal if my epididymis was bigger on left than the right? (healthtap.com)
  • Bovine Epididymis Total Protein (protein lysate) is isolated from freshly harvested tissues of single healthy normal donor. (creativebiomart.net)
  • What is the definition or description of: epididymis? (healthtap.com)
  • Is it possible to lose the epididymis on one side when you're absolutely sure you don't feel it, or can it only perhaps shrink but never waste away? (healthtap.com)
  • Cysts arising from this epididymis usually are small, sometimes multiple. (healthtap.com)
  • Wong, P. 2009-03-31 00:00:00 Previous studies from our laboratory have provided evidence for the existence of a local reninangiotensin system in the rat epididymis. (deepdyve.com)
  • Dear, I need an help, my boyfriend is suffering of cronical epididymis from February 2013.He tried all types of cares but nothing works.I need an help? (healthtap.com)
  • If you want to look at its pic, type "pic of epididymis" to search online. (healthtap.com)
  • Angiotensin II receptors: Localization of type I and type II in rat epididymides of different. (deepdyve.com)