The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.
The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The network of channels formed at the termination of the straight SEMINIFEROUS TUBULES in the mediastinum testis. Rete testis channels drain into the efferent ductules that pass into the caput EPIDIDYMIS.
Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific. They are important molecular agents in the process of sperm maturation.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Paired ducts in the human male through which semen is ejaculated into the urethra.
The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct.
Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)
Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.
Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.
A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.
A count of SPERM in the ejaculum, expressed as number per milliliter.
The convoluted tubules in the TESTIS where sperm are produced (SPERMATOGENESIS) and conveyed to the RETE TESTIS. Spermatogenic tubules are composed of developing germ cells and the supporting SERTOLI CELLS.
The surgical removal of one or both testicles.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Liquid components of living organisms.
The epithelium lining the seminiferous tubules composed of primary male germ cells (SPERMATOGONIA) and supporting SERTOLI CELLS. As SPERMATOGENESIS proceeds, the developing germ cells migrate toward the lumen. The adluminal compartment, the inner two thirds of the tubules, contains SPERMATOCYTES and the more advanced germ cells.
The measurement of an organ in volume, mass, or heaviness.
Pathological processes of the TESTIS.
Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Achievement of full sexual capacity in animals and in humans.
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.
Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.
An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.
An oviparous burrowing mammal of the order Monotremata native to Australia, Tasmania, and New Guinea. It has hair mingled with spines on the upper part of the body and is adapted for feeding on ants.
Surgical anastomosis or fistulization of the spermatic ducts to restore fertility in a previously vasectomized male.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Chemical substances or agents with contraceptive activity in males. Use for male contraceptive agents in general or for which there is no specific heading.
The posterior filiform portion of the spermatozoon (SPERMATOZOA) that provides sperm motility.
A chlorinated PROPANEDIOL with antifertility activity in males used as a chemosterilant in rodents.
A family of herbivorous leaping MAMMALS of Australia, New Guinea, and adjacent islands. Members include kangaroos, wallabies, quokkas, and wallaroos.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Surgical removal or artificial destruction of gonads.
The anterior portion of the spermatozoon (SPERMATOZOA) that contains mainly the nucleus with highly compact CHROMATIN material.
An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Either of a pair of tubular structures formed by DUCTUS DEFERENS; ARTERIES; VEINS; LYMPHATIC VESSELS; and nerves. The spermatic cord extends from the deep inguinal ring through the INGUINAL CANAL to the TESTIS in the SCROTUM.
A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.
Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA.
DEFENSINS found mainly in epithelial cells.
Carrier proteins produced in the Sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. They participate in the transport of androgens. Androgen-binding protein has the same amino acid sequence as SEX HORMONE-BINDING GLOBULIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
A species of macaque monkey that mainly inhabits the forest of southern India. They are also called bonnet macaques or bonnet monkeys.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
A selective pre- and post-emergence herbicide. (From Merck Index, 11th ed)
A cystic dilation of the EPIDIDYMIS, usually in the head portion (caput epididymis). The cyst fluid contains dead SPERMATOZOA and can be easily differentiated from TESTICULAR HYDROCELE and other testicular lesions.
A cutaneous pouch of skin containing the testicles and spermatic cords.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.
An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.

Inhibition by amiloride of sodium-dependent fluid reabsorption in the rat isolated caudal epididymis. (1/2450)

The rate of fluid reabsorption was studied in the rat isolated caudal epididymal sac in vitro. 2 Part of the fluid reabsorption was found to be dependent on intraluminal Na+. Amiloride (0.1 mM) completely inhibited this component of fluid reabsorption. 3 The log dose-inhibition curve to amiloride was sigmoid and the IC50 value was found to be 1.6 muM.  (+info)

Morphology of the epididymal region and ductus deferens of the turkey (Meleagris gallopavo). (2/2450)

The ductal system of the reproductive tract of the male domestic turkey was studied by gross dissection and light microscopy of paraffin and Epon embedded tissues. The succession of ductules as one passes caudally from the testis was as follows: seminiferous tubules; rete testis; ductuli efferentes; connecting ductules; ductus epididymidis; ductus deferens; receptaculum ductus deferentis; papilla ductus deferentis. Non-ciliated cells of the male tract consisted of squamous and low cuboidal cells of the rete testis, granulated columnar cells lining the ductuli efferentes and connective ductules; agranulated columnar cells which formed the epithelium of the ductus epididymidis, ductus deferens, receptaculum and papilla ductus deferentis; and basal cells which were found in increasing number from the ductuli efferentes to the papilla. The basal cells had a reduced amount of cytoplasm and stained more intensely than the other cell types. Ciliated cells were apparent in the ductuli efferentes and connecting ductules, and these consistently stained lighter than the non-ciliated cells. Non-ciliated columnar cells of the ductuli efferentes and connecting ductules contained chromatophilic granules. Cytoplasmic blebbing into the ductal lumina was found associated with these non-ciliated cells as well as the agranular cells of the ductus epididymidis and deferens. Evidence obtained from this study suggests that the non-ciliated cells of the ductuli efferentes, ductus epididymidis and ductus deferens have a contribution to make to the seminal plasma by apocrine secretion.  (+info)

Glutathione-independent prostaglandin D2 synthase in ram and stallion epididymal fluids: origin and regulation. (3/2450)

Microsequencing after two-dimensional electrophoresis revealed a major protein, glutathione-independent prostaglandin D2 synthase (PGDS) in the anterior epididymal region fluid of the ram and stallion. In this epididymal region, PGDS was a polymorphic compound with a molecular mass around 30 kDa and a range of pI from 4 to 7. PGDS represented 15% and 8% of the total luminal proteins present in this region in the ram and stallion, respectively. The secretion of the protein as judged by in vitro biosynthesis, and the presence of its mRNA as studied by Northern blot analysis, were limited to the proximal caput epididymidis. Using a specific polyclonal antibody raised against a synthetic peptide, PGDS was found throughout the epididymis, decreasing in concentration toward the cauda region. PGDS was also detected in the testicular fluid and seminal plasma by Western blotting. Castration and efferent duct ligation in the ram led to a decrease in PGDS mRNA and secretion. PGDS mRNA was not detected in the stallion 1 mo after castration, and it was restored by testosterone supplementation. This study showed that PGDS is present in the environment of spermatozoa throughout the male genital tract. Its function in the maturation and/or protection of spermatozoa is unknown.  (+info)

Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. (4/2450)

An acidic environment is important for sperm maturation in the epididymis and also helps to maintain mature sperm in an immotile state during storage in this organ. Both an Na+/H+ exchanger and an H+ATPase have been implicated in this process. The H+ATPase is concentrated in specialized apical (and/or narrow) and clear cells of the epididymis, while the Na+/H+ exchanger has not yet been localized in situ. As in other proton-secreting epithelia, bicarbonate transport occurs in the epididymis, where it is implicated in luminal acidification. In this study we used an antibody raised against a fusion protein (maltose-binding protein: MBP-NBC-5) from the C-terminus of the recently cloned rat kidney Na+/HCO3- cotransporter (NBC) to localize this protein in the epididymis and vas deferens of the rat. The distribution of the respective mRNA was mapped by in situ hybridization. NBC message was strongly expressed in the initial segment and the intermediate zone of the epididymis, and the NBC-5 antibody gave a strong basolateral staining in both principal cells and apical/narrow cells in this region. Western blotting revealed a single band at about 160 kDa in the epididymis. The intensity of staining as well as mRNA levels decreased in the cauda epididymidis and in the vas deferens, where only weak staining was seen. Basolateral NBC may function in parallel with apical proton secretion to regulate luminal acidification and/or bicarbonate reabsorption in the excurrent duct system.  (+info)

Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis. (5/2450)

Gamma-glutamyl transpeptidase (GGT) mRNA-IV and polyomavirus enhancer activator 3 (PEA3) mRNA are highly expressed in the initial segment of the rat epididymis, and both are regulated by testicular factors. PEA3 protein in rat initial segment nuclear extracts has been shown to bind to a PEA3/Ets binding motif, which is derived from the partially characterized GGT mRNA-IV promoter region. This suggests that PEA3 may be involved in regulating transcription from the rat GGT mRNA-IV gene promoter in the initial segment. Using DNA oligonucleotide primers and DNA sequencing analysis, an approximately 1500-basepair (bp) DNA sequence at the 5' region of the promoter was obtained. Using transient transfection, PEA3 activated transcription of the rat GGT mRNA-IV promoter only in cultured epididymal cells from the rat initial segment, but not in Cos-1 or NRK-52E cells. Promoter deletion analysis indicated that a PEA3/Ets binding motif between nucleotides -22 and -17 is the functional site for PEA3 to activate transcription of GGT promoter IV and that an adjacent Sp1 binding motif is also required to maintain promoter IV activity in epididymal cells. Transcriptional activation of promoter IV was shown to be epididymal cell-specific and PEA3-specific. In addition, PEA3 may act as a weak repressor for transcription of promoter IV, probably using a PEA3/Ets binding motif(s) distal to the transcription start site. A model of how PEA3 is involved in the regulation of transcription of GGT promoter IV in epididymal cells is proposed.  (+info)

An intact sperm nuclear matrix may be necessary for the mouse paternal genome to participate in embryonic development. (6/2450)

We have been interested in determining the minimally required elements in the sperm head that are necessary in order for the paternal genome to participate in embryogenesis. We used an ionic detergent, mixed alkyltrimethylammonium bromide (ATAB), plus dithiothreitol (DTT) to remove the acrosome and almost all of the perinuclear theca, leaving only the sperm nucleus morphologically intact. We also tested the stability of the sperm nuclear matrix by the ability to form nuclear halos. Sperm nuclei washed in freshly prepared 0.5% ATAB + 2 mM DTT completely decondensed when extracted with salt, but nuclei washed in the same buffer that was 1 wk old, and then extracted with salt, produced nuclear halos, indicating stable nuclear matrices. When we treated sperm heads with freshly prepared ATAB+DTT and injected them into oocytes, none of the oocytes developed into live offspring. In contrast, sperm heads treated in the same way but with 1-wk-old ATAB+DTT solution could support development of about 30% of the oocytes to live offspring. Electron microscopy demonstrated that most of the perinuclear theca had been removed in both cases. These data suggest that at least in the mouse, the only component of the spermatozoa that is crucial for participation in embryologic development is the sperm nucleus with a stable nuclear matrix.  (+info)

Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence. (7/2450)

With slight modification of a trypsin digestion technique, Rickettsia rickettsii were demonstrated specifically by immunofluorescence staining in Formalin-fixed, paraffin-embedded tissue sections from a human, rhesus monkey, and guinea pig with Rocky Mountain spotted fever and in infected membranes from a chicken embryo. Tissues were cut at 4 micron and, using geltain as a tissue adhesive, were hydrated in a routine manner. Sections were then digested in refrigerated 0.1% trypsin for 16 h, washed, and stained specifically for R. rickettsii by direct or indirect immunofluorescence. Rickettsial organisms were localized in affected vessels of the mammalian species and within the yolk sac epithelium of the chicken embryo. Specificity was confirmed by adsorbing antibody conjugates with R. rickettsii organisms. Trypsin digestion probably decreased tissue proteins which interfered with immunochemical attachment of antibody to the rickettsiae. The technique is valuable in that a diagnosis of Rocky Mountain spotted fever can be confirmed from Formalin-fixed tissues processed in a routine manner.  (+info)

Reversing adipocyte differentiation: implications for treatment of obesity. (8/2450)

Conventional treatment of obesity reduces fat in mature adipocytes but leaves them with lipogenic enzymes capable of rapid resynthesis of fat, a likely factor in treatment failure. Adenovirus-induced hyperleptinemia in normal rats results in rapid nonketotic fat loss that persists after hyperleptinemia disappears, whereas pair-fed controls regain their weight in 2 weeks. We report here that the hyperleptinemia depletes adipocyte fat while profoundly down-regulating lipogenic enzymes and their transcription factor, peroxisome proliferator-activated receptor (PPAR)gamma in epididymal fat; enzymes of fatty acid oxidation and their transcription factor, PPARalpha, normally low in adipocytes, are up-regulated, as are uncoupling proteins 1 and 2. This transformation of adipocytes from cells that store triglycerides to fatty acid-oxidizing cells is accompanied by loss of the adipocyte markers, adipocyte fatty acid-binding protein 2, tumor necrosis factor alpha, and leptin, and by the appearance of the preadipocyte marker Pref-1. These findings suggest a strategy for the treatment of obesity by alteration of the adipocyte phenotype.  (+info)

Reference:

American Urological Association. (2019). Epididymitis. Retrieved from

Some common types of testicular diseases include:

1. Testicular torsion: This is a condition where the spermatic cord becomes twisted, cutting off blood flow to the testicle. It is a medical emergency and can cause permanent damage if not treated promptly.
2. Epididymitis: This is an inflammation of the epididymis, a tube that runs along the back of the testicle and helps to store and transport sperm. It can be caused by bacterial infections or viral infections such as chlamydia or gonorrhea.
3. Orchitis: This is an inflammation of the testicles, usually caused by a virus or bacterial infection.
4. Hydrocele: This is a build-up of fluid around the testicle, which can be caused by infection, injury, or other factors.
5. Varicocele: This is a swelling of the veins in the scrotum, which can be caused by a blockage or weakness in the valves that control blood flow.
6. Testicular cancer: This is a type of cancer that affects the testicles, and it is relatively rare but can be aggressive if left untreated.
7. Undescended testicle(s): This is a condition where one or both testicles fail to descend from the abdomen into the scrotum during fetal development.
8. Testicular atrophy: This is a shrinkage of the testicles, which can be caused by a range of factors including aging, injury, or certain medical conditions.
9. Painful ejaculation: This is a condition where ejaculation causes pain in the testicles, and it can be caused by a range of factors such as inflammation or infection.
10. Low testosterone: This is a condition where the levels of testosterone in the body are lower than normal, which can cause a range of symptoms including low sex drive, fatigue, and osteoporosis.

It's important to note that some of these conditions can be caused by other factors as well, so it's always best to consult with a healthcare professional for an accurate diagnosis and treatment plan.

Symptoms of orchitis may include:

* Scrotal pain
* Swelling of the scrotum
* Redness and tenderness of the scrotum
* Fever
* Chills
* Abdominal pain
* Nausea and vomiting

Treatment for orchitis typically involves antibiotics to clear up any bacterial infections, as well as supportive care such as rest, ice packs, and over-the-counter pain medication. In severe cases, hospitalization may be necessary to monitor and treat the condition.

Prevention of orchitis includes avoiding close contact with people who have the infection, practicing safe sex, and maintaining good hygiene. Vaccination against certain types of bacteria that can cause orchitis, such as the H. influenzae type b (Hib) vaccine, can also help prevent the condition.

It is important to seek medical attention if symptoms of orchitis are present, as early treatment can help prevent complications and improve outcomes.

Male infertility can be caused by a variety of factors, including:

1. Low sperm count or poor sperm quality: This is one of the most common causes of male infertility. Sperm count is typically considered low if less than 15 million sperm are present in a sample of semen. Additionally, sperm must be of good quality to fertilize an egg successfully.
2. Varicocele: This is a swelling of the veins in the scrotum that can affect sperm production and quality.
3. Erectile dysfunction: Difficulty achieving or maintaining an erection can make it difficult to conceive.
4. Premature ejaculation: This can make it difficult for the sperm to reach the egg during sexual intercourse.
5. Blockages or obstructions: Blockages in the reproductive tract, such as a blockage of the epididymis or vas deferens, can prevent sperm from leaving the body during ejaculation.
6. Retrograde ejaculation: This is a condition in which semen is released into the bladder instead of being expelled through the penis during ejaculation.
7. Hormonal imbalances: Imbalances in hormones such as testosterone and inhibin can affect sperm production and quality.
8. Medical conditions: Certain medical conditions, such as diabetes, hypogonadism, and hyperthyroidism, can affect fertility.
9. Lifestyle factors: Factors such as smoking, excessive alcohol consumption, and stress can all impact fertility.
10. Age: Male fertility declines with age, especially after the age of 40.

There are several treatment options for male infertility, including:

1. Medications to improve sperm count and quality
2. Surgery to repair blockages or obstructions in the reproductive tract
3. Artificial insemination (IUI) or in vitro fertilization (IVF) to increase the chances of conception
4. Donor sperm
5. Assisted reproductive technology (ART) such as ICSI (intracytoplasmic sperm injection)
6. Hormone therapy to improve fertility
7. Lifestyle changes such as quitting smoking and alcohol, losing weight, and reducing stress.

It's important to note that male infertility is a common condition and there are many treatment options available. If you're experiencing difficulty conceiving, it's important to speak with a healthcare provider to determine the cause of infertility and discuss potential treatment options.

This definition of 'Genital Diseases, Male' is from the Healthcare Professionals Network (HPN) Thesaurus, a comprehensive collection of terms used in healthcare and related fields.

Cryptorchidism can be classified into two types:

1. Abdomenal cryptorchidism: In this type, the testis is located in the abdominal cavity above the inguinal ring and is not covered by any skin or membrane.
2. Inguinoscrotal cryptorchidism: In this type, the testis is located in the inguinal canal and may be covered by a thin layer of skin or membrane.

Cryptorchidism is usually diagnosed at birth or during childhood, and it can occur as an isolated condition or as part of other congenital anomalies. Treatment options for cryptorchidism include:

1. Watchful waiting: In mild cases, doctors may choose to monitor the child's development and delay any treatment until they are older.
2. Surgical repair: In more severe cases or those that cause discomfort or other complications, surgery may be recommended to move the testes into the scrotum.
3. Hormone therapy: In some cases, hormone therapy may be used to stimulate the descent of the testes.
4. Assisted reproductive technology (ART): In cases where fertility is a concern, ART such as in vitro fertilization (IVF) may be recommended.

It's important to note that cryptorchidism can increase the risk of complications such as testicular cancer, infertility, and twisting or inflammation of the testes (torsion). Regular check-ups with a healthcare provider are essential for monitoring and managing this condition.

Spermatoceles are usually small and do not cause any symptoms. However, if they become large enough, they can cause discomfort or pain in the scrotum or testicles. They may also affect fertility by blocking the flow of sperm from the epididymis into the vas deferens.

Spermatocele is a type of hydrocele, which means that it is caused by an accumulation of fluid within a closed sac-like structure. Hydroceles can occur in other parts of the body, such as the groin or abdomen, but spermatocele specifically affects the epididymis.

The exact cause of spermatocele is not known, but it may be related to inflammation or blockage of the epididymis. It can also occur as a result of surgery or trauma to the groin area.

Diagnosis of spermatocele is usually made through ultrasound or scrotal imaging. Treatment for spermatocele may involve draining the fluid from the cyst, or in some cases, surgical removal of the affected portion of the epididymis.

In conclusion, a spermatocele is a benign cyst that forms in the epididymis and can cause discomfort, pain, or fertility issues in men. It is important to seek medical attention if symptoms persist or worsen over time.

The epididymis (/ɛpɪˈdɪdɪmɪs/; plural: epididymides /ɛpɪdɪˈdɪmədiːz/ or /ɛpɪˈdɪdəmɪdiːz/) is a tube that connects a testicle to ... 1296 The epididymis can be divided into three main regions: The head (Latin: caput). The head of the epididymis receives ... The epididymis is situated posterior and somewhat lateral to the testis. The epididymis is invested completely by the tunica ... H&E stain Micrograph Deep dissection of epididymis Epididymis evolution from reptiles to mammals Epididymal hypertension - ...
... may refer to: Inferior ligament of epididymis Superior ligament of epididymis This disambiguation page ... lists articles associated with the title Ligament of epididymis. If an internal link led you here, you may wish to change the ...
The appendix of the epididymis (or pedunculated hydatid) is a small stalked appendage (sometimes duplicated) on the head of the ... Torsion of Appendix Epididymis Anatomy image:7754 at the SUNY Downstate Medical Center inguinalregion at The Anatomy Lesson by ... epididymis. It is usually regarded as a detached efferent duct. This structure is derived from the Wolffian duct (Mesonephric ...
The superior ligament of the epididymis is a strand of fibrous tissue which is covered by a reflection of the tunica vaginalis ... and connects the upper aspect of the epididymis with the testis. v t e (Sexual anatomy, Ligaments, All stub articles, Ligament ...
The inferior ligament of the epididymis is a strand of fibrous tissue which is covered by a reflection of the tunica vaginalis ... and connects the lower aspect of the epididymis with the testis. v t e (Sexual anatomy, Ligaments, All stub articles, Ligament ...
As a result of the epididymis being attached to the testis, and the cauda epididymis extending below the lower extremity of the ... Reid, B.L. & Cleland, K.W. (1957). The structure and function of the epididymis I. The histology of the rat epididymis. ... In scrotal mammals the epididymis is attached to the testes in an extra-abdominal position where the cauda epididymis extends ... In contrast, extensive studies of the echidna epididymis show that the monotreme epididymis lacks a middle segment. It is only ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... In the male the duct persists, and forms the tube of the epididymis, the vas deferens and the ejaculatory duct, while the ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... which is sometimes found in front of the spermatic cord above the head of the epididymis. In the female the mesonephric bodies ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, ...
the epididymis. Some consider epididymal stereocilia to be a variant of microvilli, rather than their own distinct type of ... Stereocilia are found in the vas deferens, the epididymis, and the sensory cells of the inner ear. Stereocilia are cylindrical ...
Although both epididymis cyst and spermatocele may be referred as the same, the epididymis cyst does not contain sperm and it ... However, if the epididymis becomes injured, then there is a chance that the sperm will not mature and a man will not be able to ... Epididymis cysts larger than 10mm in diameter are recommended for surgery but if there is no problem then surgery is ... Spermatocele is a fluid-filled cyst that develops at the top of the testicle of the epididymis. The fluid is usually a clear or ...
History of trauma or inflammation of the epididymis can also lead to a sperm granuloma. Sperm granulomas are seen as the body's ... However, they can cause pain and swelling of the epididymis, spermatic cord, and testis. The pain usually radiates to the groin ... While majority of sperm granulomas are present along the vas deferens, the rest of them form at the epididymis. Sperm ... Upon physical examination and an ultrasound, a solid nodule in the right epididymis was found, and medical staff suspected a ...
It mainly presents in the genital tract, in regions such as the testis and epididymis. Because of this, researchers had a ... "Adenomatoid tumor of the epididymis". Archived from the original on 2007-06-15. Retrieved 2007-12-15. "Adenomatoid Tumor - ...
While in the epididymis the spermatozoa gain motility and become capable of fertilization. However, transport of the mature ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells with the aid of ... The initial stages occur within the testes and progress to the epididymis where the developing gametes mature and are stored ... Maturation occurs in the epididymis. The location [Testes/Scrotum] is specifically important as the process of spermatogenesis ...
Joseph A, Shur BD, Hess RA (2011). "Estrogen, efferent ductules, and the epididymis". Biol Reprod. 84 (2): 207-217. doi:10.1095 ... and lack of spermatozoa in the epididymis has been observed in conjunction with defects in MCC development. "Geminin coiled- ...
Paraovarian cyst Jason S Chang (7 June 2022). "Torsion of the Appendices and Epididymis". Medscape. Updated: Oct 20, 2016. ...
Eylar EH, Murakami M (1966). "beta-Aspartyl-N-acetylglucosaminidase from epididymis". Methods Enzymol. Methods in Enzymology. 8 ...
Whilst in the epididymis, they acquire motility. However, transport of the mature spermatozoa through the remainder of the male ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells, with the aid of ...
"Testis and epididymis - Sertoli cell tumor, NOS". www.pathologyoutlines.com. Retrieved 2016-12-06. Leach S, Heatley JJ, Pool RR ...
One study using ultrasound found that the epididymides of patients with post-vasectomy pain syndrome were enlarged and full of ... There is a noticeable enlargement of the epididymides in vasectomized men. Sperm sometimes leak from the vas deferens of ... When pain in the epididymides is the primary symptom, post-vasectomy pain syndrome is often described as congestive ... Jarvis LJ, Dubbins PA (1989). "Changes in the epididymis after vasectomy: sonographic findings". AJR. American Journal of ...
402-. ISBN 978-0-323-08619-6. Robaire B, Henderson NA (May 2006). "Actions of 5alpha-reductase inhibitors on the epididymis". ... epididymides, skin, hair follicles, liver, kidneys, and brain, among others. By inhibiting 5α-reductase and thus preventing DHT ... and decreases motility and normal morphology of spermatozoa in the epididymis. Neurosteroids like 3α-androstanediol (derived ...
They also form the epididymis and the paradidymis. The sperm differentiate inside the seminiferous tubules, then swim down ...
Caccamo D, Socias M, Truchet C (1991). "Malignant Brenner tumor of the testis and epididymis". Arch. Pathol. Lab. Med. 115 (5 ...
Expression of ADAM7 is higher in the head (Caput) of the epididymis and decreases in cells towards the distal epididymis. ADAM7 ... Secretion in this manner is an apocrine secretion in which apical blebs containing a portion of the epididymis cell are ... ADAM7 is secreted by epididymis cells and transferred to the maturing sperm's surface. As determined through mouse gene knock- ... ADAM7 is synthesized in epididymis cells and transferred to the membrane of immature sperm cells as they traverse the ...
A second tube, the ductulus aberrans superior, occurs in the head of the epididymis; it is connected with the rete testis. This ... Occasionally it is found unconnected with the epididymis. ... connected with the lower part of the canal of the epididymis, ...
Cells of the epididymis also have ACVR2A receptors present. ACVR2B receptors were found to be localized in the rete testis. The ...
The contractions rapidly force sperm out of each epididymis. They also force the contents of seminal vesicles and the prostate ...
The second part of the duct system is the vas deferens, a muscular tube that begins at the lower end of the epididymis.[page ... The first part of this system is the epididymis. The testicles converge to form the seminiferous tubules, coiled tubes at the ...
Epididymis are medium-sized, discoid, tightly packed masses of ducting standing upright on either side of the atrium and ... Vas deferens is thin ducts running from epididymis posteriorly. Testisacs is ovoid, approximately 1.5 times the size of ovisacs ...
Fröhlich O, Po C, Murphy T, Young LG (2000). "Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2 ... Fröhlich O, Po C, Young LG (April 2001). "Organization of the human gene encoding the epididymis-specific EP2 protein variants ... This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins ... "Vasectomy influences expression of HE1 but not HE2 and HE5 genes in human epididymis". Journal of Andrology. 25 (1): 30-43. doi ...
Infection causes severe inflammation of the epididymis, particularly the tail. Brucella ovis, reviewed and published by Wikivet ...
The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.. ...
Sperm stasis is most commonly seen in the cauda epididymis following cessation of sperm production by the testis. ... Epididymis - Sperm Stasis. Narrative. Comment:. Sperm stasis is most commonly seen in the cauda epididymis following cessation ... Epididymis - Sperm Stasis. Sperm stasis is present on the left and atrophic epididymal ducts on the right in a male F344/N rat ... Epididymis - Sperm Stasis. Sperm stasis is present on the left and ducts without sperm on the right in a male B6C3F1 mouse from ...
Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer Pedrada Innao 1 , ... Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer Pedrada Innao et al. ... Human epididymis protein 4 (HE4) is a novo diagnostic tumor marker for EOC. The combination of HE4 and carcinoma antigen 125 ( ... Evaluation of follow-up observation using human epididymis protein 4, a tumor marker, in patients with ovarian cancer. Uno M, ...
Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas ... Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas ... is the gene for human epididymis protein 4 (HE4). To ascertain its clinical utility, we did a comprehensive assessment of HE4 ...
Liver, Lung, Prostrate, Mesenteric Lymph Nodes, Seminal Vesicle, Urinary Bladder, Testis and Epididymis, Thryoid, Trachea, ...
Order Monkey Epididymis cDNA Cynomolgus 01010099674 at Gentaur Epididymis Cynomolgus ...
Mrs can be epididymis inflammation erectile dysfunction ruthless enough, but the land guy is still a bit rustic, not to mention ... Sir quit, went to the he and my to make a fuss, and was finally pushed out He had already retired anyway, so epididymis ... Epididymis Inflammation Erectile Dysfunction • Strongest Male Enhancement • Uši A Vítr *24 hour sex pills ... The epididymis inflammation erectile dysfunction gunshots rang out and the police car lost control immediately As far as people ...
Sperm traverse the epididymis and acquire new proteins and glycoproteins on their plasma membranes even though they are ... Sperm traverse the epididymis and acquire new proteins and glycoproteins on their plasma membranes even though they are ... 1995) Identification of osteopontin (OPN) mRNA and protein in the rat testis and epididymis, and on sperm. Mol Reprod Dev 40:16 ... 2001) Expression of crisp-1 mRNA splice variants in the rat epididymis, and comparative analysis of the rat and mouse crisp-1 ...
Epididymis and fertility : biology and pathology / International Colloquium on Epididymis and Fertility, Strasbourg, October 24 ... By: International Colloquium on Epididymis and Fertility (1980 : Strasbourg, France)Contributor(s): Bollack, Claude , Clavert, ... Epididymis -- physiology -- physiopathology -- congresses , Fertility -- congressesNLM classification: WJ 800 ...
The aim of this research is to study the influence of morphological deviations in the testes and epididymides in male Siberian ... Morphological abnormalities in the testes and epididymides of roe deer that affect spermatogenesis. Ilya Sosnovsky*, Natalia ... Histological analysis of the testes and epididymides showed violations in the composition of the structural elements of this ... from which the testes with epididymides were selected, and visual morphometric and histological studies were performed using ...
Seminal vesicles carry the sperms from epididymis to urethra ... In human beings epididymis stores the sperms for some time in ... What are the functions of the epididymis and the seminal vesicles? Anatomy & Physiology The Human Body Reproductive System ... In human beings epididymis stores the sperms for some time in which they mature. Seminal vesicles carry the sperms from ...
Spermatozoa from the testes exhibited bright fluorescence over the entire head; those from the caput epididymides generally ... Changes in distribution of labile zinc in mouse spermatozoa during maturation in the epididymis assessed by the fluorophore ... fluoresced more brightly in the post-acrosomal region; and spermatozoa from the caudae epididymides fluoresced less brightly, ...
Primary Leiomyosarcoma of Epididymis: One Case Report. Yao-Dong Han1 , Hong-Jie Chen1 *, Dong-Hai Li2 and Wu Li3 ... Han Y-D, Chen H-J, Li D-H, Li W. Primary Leiomyosarcoma of Epididymis: One Case Report. World J Surg Surgical Res. 2021; 4: ... The effect of chemotherapy and radiation on the leiomyosarcoma of the epididymis remains unclear. Recurrence is common, so ...
Epididymis / drug effects * Hyperlipidemias / drug therapy* * Hypolipidemic Agents / pharmacology* * Intra-Abdominal Fat / drug ...
Epididymis. A long tube that is located near each testicle. The epididymis is the tube which moves the sperm from the testicles ... The vas deferens is between the epididymis and the urethra and connects these together. ...
Epididymis. 1. Weight loss, no. patients/no. total (%)‡. 15/17 (88.2). Prolonged fever, no. patients/no. total (%)§. 8/16 (50) ...
Can the epididymis be so prominent! How accurate is the USG! Can it miss the testicular lump?. If its not any tumor then what ... Epididymis is normal in size & isoecogenic.). But from then I was also feeling something like one more lump attached to my ... Both epididymis appear normal in size.. Right testis = 3.5 x 2.8 x 1.6 cm.. Left Testis = 3.5 x 2.7 x 1.8 cm.. Two anechoic ... He told me its a 10 mm cyst in my right epididymis. He also told there is nothing to worry coz its never going to turn into ...
Reproductive: Paternal effects: Testes, epididymis, sperm duct. TOXID9 4,65,1984. inhalation/rat 281 ppm/6H (6-15D pregnant). ...
You may have tenderness in a small area of the testicle where the epididymis is attached. A large area of swelling may develop ...
Ultrasonography of the testes (to help disclose abnormalities in the testes and epididymides; rarely indicated) ...
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE ...
Decreased epididymis weight in male rats. ,60 000. Lip Balm - toddler (daily oral). 0.07 µg/kg bw/day. 1.9 mg/kg bw/day (BMDL)b ... Decreased cauda epididymis weight in male rats. ,200 000. Body lotion - adult (per event inhalation). 21 µg/m3. 6.9 mg/m3 (AEGL ... confidence limit on the dose corresponding to a change in cauda epididymis weight in male rats equal to one standard deviation ... including decreased cauda and whole epididymis weights, decreased testes weight, and altered sperm parameters, with rats ...
Main Research Areas: Epididymis; sperm; testis; contraception. *Clara Cheng, Program Director. Main Research Areas: Trophoblast ... Main Research Areas: Spermatogenesis; testis biology; sperm function; male reproductive tract (including epididymis and seminal ...
Epididymides Skin (hind limb). Esophagus Spinal cord (cervical, mid-thoracic and lumbar). Eyes. Gross lesions Spleen. Heart ... Epididymides Skin (hind limb). Esophagus Spinal cord (cervical, mid-thoracic and lumbar). Eyes. Gross lesions Spleen. Heart ... Epididymides Testes. Heart Thymus. Kidneys Uterus. Liver. HISTOPATHOLOGY: Yes Adrenals Ovaries. Aorta (thoracic) Pancreas. Bone ... Epididymides Testes. Heart Thymus. Kidneys Uterus. Liver. HISTOPATHOLOGY: Yes Adrenals Ovaries. Aorta (thoracic) Pancreas. Bone ...
Epididymides: When compared with controls, the mean absolute and relative weights of epididymides were higher in animals from ... Epididymides. Subgroup B (0, 400, 600 or 750 mg/kg bw/day then sacrificed 12 or 24 h after the last dosing):. - Slight to ... Epithelial hypertrophy in epididymides was also observed along with decreased size of the lumen. At 750 mg/kg bw/day for 7 days ... Testes, epididymides and livers of animals from subgroups A and B and sacrificed 12 or 24 h post treatment were weighed at ...
Alongside the testicles are the epididymis and the vas deferens, which transport sperm. The epididymis (pronounced: ep-uh-DID- ... Also called the ductus deferens, the vas deferens is a thin muscular tube that transports the sperm from the epididymis to the ... Next to each testicle, the epididymis is a tube where sperm is stored. From here, sperm are transported to the vas deferens. ... The head contains genetic material (genes). The sperm move into the epididymis, where they complete their development. ...
  • Sperm stasis is most commonly seen in the cauda epididymis following cessation of sperm production by the testis. (nih.gov)
  • A sperm-fil ed dilated duct in the head of the epididymis, with focal areas of mineralization (arrows), in a male B6C3F1 mouse from a subchronic study. (nih.gov)
  • They are most commonly seen in the initial segment or the caput region of the mouse epididymis (Figure 1) and are fil ed with varying amounts of sperm. (nih.gov)
  • and spermatozoa from the caudae epididymides fluoresced less brightly, with foci of fluorescence over the sperm head which were lost after extraction with Triton X-100 and hence appeared to be membrane -associated. (bvsalud.org)
  • Sperm traverse the epididymis and acquire new proteins and glycoproteins on their plasma membranes even though they are incapable of nuclear DNA transcription and mRNA translation. (grantome.com)
  • Antibodies to protein D are available in other laboratories, and their immunolocalization studies indicate that protein D is primarily synthesized in regions of the epididymis different from those of protein E and the antibody localizes to the head of the sperm rather than to the tail. (grantome.com)
  • The epididymis is the tube which moves the sperm from the testicles. (hopkinsmedicine.org)
  • Alongside the testicles are the epididymis and the vas deferens, which transport sperm. (kidshealth.org)
  • Next to each testicle, the epididymis is a tube where sperm is stored. (kidshealth.org)
  • Also called the ductus deferens, the vas deferens is a thin muscular tube that transports the sperm from the epididymis to the urethra. (kidshealth.org)
  • they were divided into 2 groups of 12 individuals each, from which the testes with epididymides were selected, and visual morphometric and histological studies were performed using generally accepted methods. (e3s-conferences.org)
  • The testes, bilateral epididymis, and scrotum were normal. (bmj.com)
  • The vas deferens is between the epididymis and the urethra and connects these together. (hopkinsmedicine.org)
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  • 1. Bilateral mucinous cystadenocarcinoma of the testis and epididymis. (nih.gov)
  • 7. Malignant Brenner tumor of the testis and epididymis. (nih.gov)
  • 9. [Scanning electron and light microscopic studies of the surface epithelium of the rete testis and epididymis in the boar. (nih.gov)
  • 17. Developmental expression of the glutathione S-transferase Yo subunit in the rat testis and epididymis using light microscope immunocytochemistry. (nih.gov)
  • 1998. Effects of environmental toxicants on the efferent ducts, epididymis and fertility. (nih.gov)
  • 2. Developmental expression of the Yf subunit of glutathione S-transferase P in epithelial cells of the testis, efferent ducts, and epididymis of the rat. (nih.gov)
  • 4. Immunocytochemical localization of the Yf subunit of glutathione S-transferase P shows regional variation in the staining of epithelial cells of the testis, efferent ducts, and epididymis of the male rat. (nih.gov)
  • The epididymis (pronounced: ep-uh-DID-uh-miss) and the testicles hang in a pouch-like structure outside the pelvis called the scrotum . (kidshealth.org)
  • Bilateral should be indicated when both epididymides are involved, with severity grade based on the more severely affected epididymis. (nih.gov)
  • If present in both epididymides, the diagnosis should be qualified as bilateral. (nih.gov)
  • Figure 1 Epididymis - Spermatocele. (nih.gov)
  • What are the functions of the epididymis and the seminal vesicles? (socratic.org)
  • We have been working for the past few years on two rat epididymis-specific secretory glycoproteins (proteins D & E) that are greater than 95% homologous at the amino acid level and are commonly considered to be identical, differing only in their glycosylation. (grantome.com)
  • Characterization and development of the regional- and cellular-specific abnormalities in the epididymis of mice with beta-hexosaminidase A deficiency. (nih.gov)
  • An infection in the epididymis can easily spread to the testicle. (medlineplus.gov)
  • You may have tenderness in a small area of the testicle where the epididymis is attached. (medlineplus.gov)
  • Human epididymis protein 4 (HE4) is a novo diagnostic tumor marker for EOC. (nih.gov)
  • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. (nih.gov)
  • Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human epididymis protein 4 (HE4). (nih.gov)
  • 10. Age-related epididymis-like intratesticular structures: benign lesions of Wolffian origin that can be misdiagnosed as testicular tumors. (nih.gov)
  • 13. [An adenoid tumor of the epididymis--electron microscopy and immunohistochemistry]. (nih.gov)
  • 3. Epithelial cells of the epididymis show regional variations with respect to the secretion of endocytosis of immobilin as revealed by light and electron microscope immunocytochemistry. (nih.gov)
  • 11. Role of epithelial clear cells of the rat epididymis in the disposal of the contents of cytoplasmic droplets detached from spermatozoa. (nih.gov)
  • 15. Vitamin E deficiency causes incomplete spermatogenesis and affects the structural differentiation of epithelial cells of the epididymis in the rat. (nih.gov)
  • In human beings epididymis stores the sperms for some time in which they mature. (socratic.org)
  • 16. Apical mitochondria-rich cells in the human epididymis: an ultrastructural, enzymohistochemical, and immunohistochemical study. (nih.gov)
  • Changes in distribution of labile zinc in mouse spermatozoa during maturation in the epididymis assessed by the fluorophore Zinquin. (bvsalud.org)
  • Our preliminary data indicate that there are both carbohydrate and amino acid differences between the two proteins that could be very important to their behavior in the epididymis. (grantome.com)
  • Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure. (nih.gov)
  • Such differential patterns of ubiquitination in the testis and epididymis, and inside the egg, may be necessary for reproductive success in humans and animals. (cdc.gov)
  • 1. Bilateral mucinous cystadenocarcinoma of the testis and epididymis. (nih.gov)
  • 2. Developmental expression of the Yf subunit of glutathione S-transferase P in epithelial cells of the testis, efferent ducts, and epididymis of the rat. (nih.gov)
  • 4. Immunocytochemical localization of the Yf subunit of glutathione S-transferase P shows regional variation in the staining of epithelial cells of the testis, efferent ducts, and epididymis of the male rat. (nih.gov)
  • 7. Malignant Brenner tumor of the testis and epididymis. (nih.gov)
  • 9. [Scanning electron and light microscopic studies of the surface epithelium of the rete testis and epididymis in the boar. (nih.gov)
  • 17. Developmental expression of the glutathione S-transferase Yo subunit in the rat testis and epididymis using light microscope immunocytochemistry. (nih.gov)
  • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. (nih.gov)
  • Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human epididymis protein 4 (HE4). (nih.gov)
  • 16. Apical mitochondria-rich cells in the human epididymis: an ultrastructural, enzymohistochemical, and immunohistochemical study. (nih.gov)
  • Figure 1 Epididymis, Epithelium - Apoptosis. (nih.gov)
  • 10. Age-related epididymis-like intratesticular structures: benign lesions of Wolffian origin that can be misdiagnosed as testicular tumors. (nih.gov)
  • Characterization and development of the regional- and cellular-specific abnormalities in the epididymis of mice with beta-hexosaminidase A deficiency. (nih.gov)
  • When present in both epididymides, the diagnosis should be clarified as bilateral and the severity score based on the more severely affected epididymis. (nih.gov)
  • In: The Epididymis: From Molecules to Clinical (Robaire B, Hinton BT, eds). (nih.gov)
  • A patient's refusal to undergo regional anesthesia for surgical procedures of the testicle and epididymis may often be rooted in the belief that he will be awake during the procedure and would just rather be "all the way asleep" for a surgery in this sensitive region. (medscape.com)
  • Color Doppler sonogram of the left epididymis in a patient with acute epididymitis. (medscape.com)
  • palpable swelling of the epididymis is usually present. (cdc.gov)
  • Normally, there is a low background level of apoptotic cells in the epididymis, but if testosterone levels decrease significantly, the number of apoptotic cells increases, first in the initial segment (Figure 1) and then proceeding distally in a wave-like manner over time through to the cauda. (nih.gov)
  • Androgenic regulation of the structure and functions of the epididymis. (nih.gov)
  • Anesthesia of the testicle and epididymis is best understood starting from the embryological origin of the respective structures. (medscape.com)