The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.
The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The network of channels formed at the termination of the straight SEMINIFEROUS TUBULES in the mediastinum testis. Rete testis channels drain into the efferent ductules that pass into the caput EPIDIDYMIS.
Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific. They are important molecular agents in the process of sperm maturation.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Paired ducts in the human male through which semen is ejaculated into the urethra.
The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct.
Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)
Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.
Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.
A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.
A count of SPERM in the ejaculum, expressed as number per milliliter.
The convoluted tubules in the TESTIS where sperm are produced (SPERMATOGENESIS) and conveyed to the RETE TESTIS. Spermatogenic tubules are composed of developing germ cells and the supporting SERTOLI CELLS.
The surgical removal of one or both testicles.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Liquid components of living organisms.
The epithelium lining the seminiferous tubules composed of primary male germ cells (SPERMATOGONIA) and supporting SERTOLI CELLS. As SPERMATOGENESIS proceeds, the developing germ cells migrate toward the lumen. The adluminal compartment, the inner two thirds of the tubules, contains SPERMATOCYTES and the more advanced germ cells.
The measurement of an organ in volume, mass, or heaviness.
Pathological processes of the TESTIS.
Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
Achievement of full sexual capacity in animals and in humans.
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.
Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.
An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.
An oviparous burrowing mammal of the order Monotremata native to Australia, Tasmania, and New Guinea. It has hair mingled with spines on the upper part of the body and is adapted for feeding on ants.
Surgical anastomosis or fistulization of the spermatic ducts to restore fertility in a previously vasectomized male.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Chemical substances or agents with contraceptive activity in males. Use for male contraceptive agents in general or for which there is no specific heading.
The posterior filiform portion of the spermatozoon (SPERMATOZOA) that provides sperm motility.
A chlorinated PROPANEDIOL with antifertility activity in males used as a chemosterilant in rodents.
A family of herbivorous leaping MAMMALS of Australia, New Guinea, and adjacent islands. Members include kangaroos, wallabies, quokkas, and wallaroos.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Surgical removal or artificial destruction of gonads.
The anterior portion of the spermatozoon (SPERMATOZOA) that contains mainly the nucleus with highly compact CHROMATIN material.
An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Either of a pair of tubular structures formed by DUCTUS DEFERENS; ARTERIES; VEINS; LYMPHATIC VESSELS; and nerves. The spermatic cord extends from the deep inguinal ring through the INGUINAL CANAL to the TESTIS in the SCROTUM.
A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.
Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA.
DEFENSINS found mainly in epithelial cells.
Carrier proteins produced in the Sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. They participate in the transport of androgens. Androgen-binding protein has the same amino acid sequence as SEX HORMONE-BINDING GLOBULIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
A species of macaque monkey that mainly inhabits the forest of southern India. They are also called bonnet macaques or bonnet monkeys.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
A selective pre- and post-emergence herbicide. (From Merck Index, 11th ed)
A cystic dilation of the EPIDIDYMIS, usually in the head portion (caput epididymis). The cyst fluid contains dead SPERMATOZOA and can be easily differentiated from TESTICULAR HYDROCELE and other testicular lesions.
A cutaneous pouch of skin containing the testicles and spermatic cords.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.
An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.

Inhibition by amiloride of sodium-dependent fluid reabsorption in the rat isolated caudal epididymis. (1/2450)

The rate of fluid reabsorption was studied in the rat isolated caudal epididymal sac in vitro. 2 Part of the fluid reabsorption was found to be dependent on intraluminal Na+. Amiloride (0.1 mM) completely inhibited this component of fluid reabsorption. 3 The log dose-inhibition curve to amiloride was sigmoid and the IC50 value was found to be 1.6 muM.  (+info)

Morphology of the epididymal region and ductus deferens of the turkey (Meleagris gallopavo). (2/2450)

The ductal system of the reproductive tract of the male domestic turkey was studied by gross dissection and light microscopy of paraffin and Epon embedded tissues. The succession of ductules as one passes caudally from the testis was as follows: seminiferous tubules; rete testis; ductuli efferentes; connecting ductules; ductus epididymidis; ductus deferens; receptaculum ductus deferentis; papilla ductus deferentis. Non-ciliated cells of the male tract consisted of squamous and low cuboidal cells of the rete testis, granulated columnar cells lining the ductuli efferentes and connective ductules; agranulated columnar cells which formed the epithelium of the ductus epididymidis, ductus deferens, receptaculum and papilla ductus deferentis; and basal cells which were found in increasing number from the ductuli efferentes to the papilla. The basal cells had a reduced amount of cytoplasm and stained more intensely than the other cell types. Ciliated cells were apparent in the ductuli efferentes and connecting ductules, and these consistently stained lighter than the non-ciliated cells. Non-ciliated columnar cells of the ductuli efferentes and connecting ductules contained chromatophilic granules. Cytoplasmic blebbing into the ductal lumina was found associated with these non-ciliated cells as well as the agranular cells of the ductus epididymidis and deferens. Evidence obtained from this study suggests that the non-ciliated cells of the ductuli efferentes, ductus epididymidis and ductus deferens have a contribution to make to the seminal plasma by apocrine secretion.  (+info)

Glutathione-independent prostaglandin D2 synthase in ram and stallion epididymal fluids: origin and regulation. (3/2450)

Microsequencing after two-dimensional electrophoresis revealed a major protein, glutathione-independent prostaglandin D2 synthase (PGDS) in the anterior epididymal region fluid of the ram and stallion. In this epididymal region, PGDS was a polymorphic compound with a molecular mass around 30 kDa and a range of pI from 4 to 7. PGDS represented 15% and 8% of the total luminal proteins present in this region in the ram and stallion, respectively. The secretion of the protein as judged by in vitro biosynthesis, and the presence of its mRNA as studied by Northern blot analysis, were limited to the proximal caput epididymidis. Using a specific polyclonal antibody raised against a synthetic peptide, PGDS was found throughout the epididymis, decreasing in concentration toward the cauda region. PGDS was also detected in the testicular fluid and seminal plasma by Western blotting. Castration and efferent duct ligation in the ram led to a decrease in PGDS mRNA and secretion. PGDS mRNA was not detected in the stallion 1 mo after castration, and it was restored by testosterone supplementation. This study showed that PGDS is present in the environment of spermatozoa throughout the male genital tract. Its function in the maturation and/or protection of spermatozoa is unknown.  (+info)

Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. (4/2450)

An acidic environment is important for sperm maturation in the epididymis and also helps to maintain mature sperm in an immotile state during storage in this organ. Both an Na+/H+ exchanger and an H+ATPase have been implicated in this process. The H+ATPase is concentrated in specialized apical (and/or narrow) and clear cells of the epididymis, while the Na+/H+ exchanger has not yet been localized in situ. As in other proton-secreting epithelia, bicarbonate transport occurs in the epididymis, where it is implicated in luminal acidification. In this study we used an antibody raised against a fusion protein (maltose-binding protein: MBP-NBC-5) from the C-terminus of the recently cloned rat kidney Na+/HCO3- cotransporter (NBC) to localize this protein in the epididymis and vas deferens of the rat. The distribution of the respective mRNA was mapped by in situ hybridization. NBC message was strongly expressed in the initial segment and the intermediate zone of the epididymis, and the NBC-5 antibody gave a strong basolateral staining in both principal cells and apical/narrow cells in this region. Western blotting revealed a single band at about 160 kDa in the epididymis. The intensity of staining as well as mRNA levels decreased in the cauda epididymidis and in the vas deferens, where only weak staining was seen. Basolateral NBC may function in parallel with apical proton secretion to regulate luminal acidification and/or bicarbonate reabsorption in the excurrent duct system.  (+info)

Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis. (5/2450)

Gamma-glutamyl transpeptidase (GGT) mRNA-IV and polyomavirus enhancer activator 3 (PEA3) mRNA are highly expressed in the initial segment of the rat epididymis, and both are regulated by testicular factors. PEA3 protein in rat initial segment nuclear extracts has been shown to bind to a PEA3/Ets binding motif, which is derived from the partially characterized GGT mRNA-IV promoter region. This suggests that PEA3 may be involved in regulating transcription from the rat GGT mRNA-IV gene promoter in the initial segment. Using DNA oligonucleotide primers and DNA sequencing analysis, an approximately 1500-basepair (bp) DNA sequence at the 5' region of the promoter was obtained. Using transient transfection, PEA3 activated transcription of the rat GGT mRNA-IV promoter only in cultured epididymal cells from the rat initial segment, but not in Cos-1 or NRK-52E cells. Promoter deletion analysis indicated that a PEA3/Ets binding motif between nucleotides -22 and -17 is the functional site for PEA3 to activate transcription of GGT promoter IV and that an adjacent Sp1 binding motif is also required to maintain promoter IV activity in epididymal cells. Transcriptional activation of promoter IV was shown to be epididymal cell-specific and PEA3-specific. In addition, PEA3 may act as a weak repressor for transcription of promoter IV, probably using a PEA3/Ets binding motif(s) distal to the transcription start site. A model of how PEA3 is involved in the regulation of transcription of GGT promoter IV in epididymal cells is proposed.  (+info)

An intact sperm nuclear matrix may be necessary for the mouse paternal genome to participate in embryonic development. (6/2450)

We have been interested in determining the minimally required elements in the sperm head that are necessary in order for the paternal genome to participate in embryogenesis. We used an ionic detergent, mixed alkyltrimethylammonium bromide (ATAB), plus dithiothreitol (DTT) to remove the acrosome and almost all of the perinuclear theca, leaving only the sperm nucleus morphologically intact. We also tested the stability of the sperm nuclear matrix by the ability to form nuclear halos. Sperm nuclei washed in freshly prepared 0.5% ATAB + 2 mM DTT completely decondensed when extracted with salt, but nuclei washed in the same buffer that was 1 wk old, and then extracted with salt, produced nuclear halos, indicating stable nuclear matrices. When we treated sperm heads with freshly prepared ATAB+DTT and injected them into oocytes, none of the oocytes developed into live offspring. In contrast, sperm heads treated in the same way but with 1-wk-old ATAB+DTT solution could support development of about 30% of the oocytes to live offspring. Electron microscopy demonstrated that most of the perinuclear theca had been removed in both cases. These data suggest that at least in the mouse, the only component of the spermatozoa that is crucial for participation in embryologic development is the sperm nucleus with a stable nuclear matrix.  (+info)

Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence. (7/2450)

With slight modification of a trypsin digestion technique, Rickettsia rickettsii were demonstrated specifically by immunofluorescence staining in Formalin-fixed, paraffin-embedded tissue sections from a human, rhesus monkey, and guinea pig with Rocky Mountain spotted fever and in infected membranes from a chicken embryo. Tissues were cut at 4 micron and, using geltain as a tissue adhesive, were hydrated in a routine manner. Sections were then digested in refrigerated 0.1% trypsin for 16 h, washed, and stained specifically for R. rickettsii by direct or indirect immunofluorescence. Rickettsial organisms were localized in affected vessels of the mammalian species and within the yolk sac epithelium of the chicken embryo. Specificity was confirmed by adsorbing antibody conjugates with R. rickettsii organisms. Trypsin digestion probably decreased tissue proteins which interfered with immunochemical attachment of antibody to the rickettsiae. The technique is valuable in that a diagnosis of Rocky Mountain spotted fever can be confirmed from Formalin-fixed tissues processed in a routine manner.  (+info)

Reversing adipocyte differentiation: implications for treatment of obesity. (8/2450)

Conventional treatment of obesity reduces fat in mature adipocytes but leaves them with lipogenic enzymes capable of rapid resynthesis of fat, a likely factor in treatment failure. Adenovirus-induced hyperleptinemia in normal rats results in rapid nonketotic fat loss that persists after hyperleptinemia disappears, whereas pair-fed controls regain their weight in 2 weeks. We report here that the hyperleptinemia depletes adipocyte fat while profoundly down-regulating lipogenic enzymes and their transcription factor, peroxisome proliferator-activated receptor (PPAR)gamma in epididymal fat; enzymes of fatty acid oxidation and their transcription factor, PPARalpha, normally low in adipocytes, are up-regulated, as are uncoupling proteins 1 and 2. This transformation of adipocytes from cells that store triglycerides to fatty acid-oxidizing cells is accompanied by loss of the adipocyte markers, adipocyte fatty acid-binding protein 2, tumor necrosis factor alpha, and leptin, and by the appearance of the preadipocyte marker Pref-1. These findings suggest a strategy for the treatment of obesity by alteration of the adipocyte phenotype.  (+info)

Electron microscopic study was made on the water reabsorption of the epithelial cells of the rat cauda epididymidis. It was shown that when the epididymal duct was reabsorbing water at a maximal rate, widely dilated intercellular spaces were seen. It is suggested that the standing gradient model of water reabsorption first proposed for the gall bladder may also operate in the cauda epididymidis ...
Dive into the research topics of Surgical and pathologic observations of epididymal tubules during microscopic epididymal sperm aspiration for intracytoplasmic sperm injection. Together they form a unique fingerprint. ...
β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological properties led us to conclude that the increased activity was not due to the expression of an isoform unrelated to the HEX A and B present in other human tissues. Measurement of enzyme levels in the three distinct epididymal regions revealed that in any given sample, activity was higher in the caput than in the corpus or cauda. Moreover, we found a striking correlation between β-HEX activity in the caput region and concentrations of blood testosterone, suggesting a possible involvement of the hormone in modulating enzyme expression. Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in the caput has a physiological relevance in human epididymis functions.. ...
The generation of single cell sequencing data from human tissues is transforming our understanding of biological mechanisms. This is particularly true for poorly studied organs and tissues that are difficult to obtain. One such tissue is the human male genital duct, the epididymis and vas deferens, which have a pivotal role in sperm maturation and hence maintenance of the species. Most models of epididymis function are based upon other mammals, which show substantial anatomic and functional diversity. Here, we construct a single cell atlas of the human proximal epididymis, which reveals detailed molecular characterization of both common and rare cell types, and hence may advance our understanding of mechanisms of male fertility.. The key functions of the epididymis are performed by the cells lining the lumen of the duct, which maintain a low pH environment necessary for sperm quiescence. These cells also secrete a wide spectrum of proteins, peptides, and RNAs that provide the necessary cues for ...
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature. Organoid cultures derived from primary human tissues facilitate the study of disease processes and the development of new therapeutics. Most men with cystic fibrosis (CF) are infertile due to defects in the epididymis and vas deferens; however, the causative mechanisms are still unclear. We used human epididymis epithelial cell (HEE) organoids and polarized HEE cell cultures to assay the CF transmembrane conductance regulator (CFTR) in the human epididymis. 3D HEE organoids and polarized 2D HEE cell cultures on membrane inserts were established from human caput epididymis. Single-cell RNA sequencing (scRNA-seq) was performed to map cell type-specific gene expression in the organoids. Using forskolin (FSK) to activate CFTR and inhibitor CFTRinh172 to block its activity, we assessed how CFTR contributes to organoid swelling and epithelial barrier function. The scRNA-seq data showed key caput epididymis cell types present in HEE organoid
TY - JOUR. T1 - Activins, follistatin and immunoregulation in the epididymis. AU - Wijayarathna, R.. AU - Hedger, M.P.. PY - 2019/9. Y1 - 2019/9. N2 - Background: The interface between the epididymis and the immune system is implicated in many male reproductive pathologies. The resident immune cell populations and immune-environment within the epididymis are significantly different from the testis, which is an immune-privileged site. Moreover, the immune cell subsets and immunological responses between different regions of the epididymis vary considerably. The cauda epididymis is more susceptible to autoimmune responses than the caput in rodent models of active immunization or suppressed immune tolerance, and in men with congenital or physical damage to the reproductive tract. Activins are members of the transforming growth factor-β family of cytokines that are crucial for testis and epididymal development; however, they also have complex immunoregulatory properties and may play an essential ...
FUNCTIONS: Spermatozoa formed in the testis enter the caput epididymis, progress to the corpus, and finally reach the cauda region, where they are stored. Sperm entering the caput epididymis are incomplete - they lack the ability to swim forward (motility) and to fertilize an egg. During their transit in the epididymis, sperm undergo maturation processes necessary for them to acquire these functions. Final maturation is completed in the female reproductive tract (capacitation).
In our previous studies, we showed that a finasteride-induced DHT deficiency may cause changes in the morphology of the seminiferous epithelium without any morphological alteration of the epididymis. In this study, we demonstrated the constitutive immunoexpression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of Wistar rats treated with finasteride for 28 days (the duration of two cycles of the seminiferous epithelium) and 56 days (the duration of one spermatogenesis). We noted that a 56-day finasteride treatment mainly caused a decrease in the level of circulating DHT, as well as a statistically insignificant decrease in the level of T. The hormone deficiency also led to a change in the iNOS immnoexpression in the testis and epididymis of the finasteride-treated rats. In vitro, DHT did not modify NO production by the epithelial cells of the caput epididymis even when stimulated with LPS and IFNγ, but it did give rise to an increase in NO production by the epithelial ...
Opec.go.th Most Effective boosted board alternative Shop, can you get testicular epididymis from male enhancement pills.. They chose a day to give a gift. The appointment was made and they were not married can you get testicular epididymis from male enhancement pills Best Man Enhancement Pill yet.. Nanyue State is cutting cialis in half adjacent boosted board alternative Low Price to Changsha State, the vassal state of the Han Dynasty.. Li Erdao And silence. If it x40 water penis pump doesn t happen, it boosted board alternative won t be beautiful.. Now my Genuine can you get testicular epididymis from male enhancement pills wife is getting angry, even if I am not, I will ask can you get testicular epididymis from male enhancement pills Is Your Best Choice to move out in three or two days, and I dare to persuade me.. It is not difficult to call Mei and Wei to retreat. But it s not.. Speaking of the last sentence, she choked up again. can you get testicular epididymis from male enhancement pills ...
E: epididymis (CA: caput, CO: corpus; CU: cauda). T: testis Other human epididymis _ specific gene products (Table 3) HUMAN EPIDIDYMAL cDNA FAMILIES HE1-HE6 Using a strategy of differential secreening of human epididymal cDNA libraries, a set of six major secretory proteins of human epididymal epithelial cells, named HE1-HE6, were identified (Kirchhoff et al, 1990). With the exception of HE5, the others are novel (human) gene products, not previously reported in animal studies. A brief description of HE1, HE2, HE3, HE4, HE5, and HE6 molecular characterization is presented in the following paragraphs. HE1: HE1 is a major secretory glycoprotein detected as a ~ 20 KDa protein, present within the epithelium and lumen of the corpus epididymis, and accumulated in the lumen of cauda epididymis and vas deferens. The mRNA encoding HE1 was found to be the most abundant gene product obtained using the strategy of differential screening. HE1 is well conserved among mammals (in chimpanzee, named EPI-1 (Perry ...
www.ivfbaby.com Percutaneous Epididymal Sperm Aspiration or PESA. A needle is passed through the scrotal skin and into the epididymis in order to aspirate sperm. Because the epididymal tubule is very delicate and convoluted, the yield with a needle is typically small and usually only sufficient for a single cycle of IVF-ICSI performed on the same day as the PESA. In male infertility occasionally sperm may not be reliable retrieved at all. PESA can be used for men with congenital absence of the vas and in lieu of vasectomy reversal. This procedure involves insertion of a small needle, under local anesthesia, directly into the epididymis for aspiration of a fewer number of sperm than would be necessary for fertilization by conventional IVF. However, in most cases there are more than enough sperm to fertilize all oocytes by ICSI. With newer cryopreservation techniques, there may even be sufficient numbers of sperm for freezing so that additional ICSI procedures could be performed in the future ...
Because our data suggest that sRNAs in mature sperm could have originated at multiple locations throughout the reproductive tract, we assessed the effect of paternal diet on sRNAs in the testis (n = 9 pairs), caput epididymis (n = 6), and cauda epididymis (n = 5) (fig. S5). Two prominent dietary effects on the cauda sperm RNA repertoire-increased abundance of glycine tRFs and decreased abundance of let-7-were recapitulated in the testis and epididymis but not in the liver, muscle, or blood (table S1). Thus, tissues throughout the male reproductive tract, including mature sperm, exhibit consistent changes in glycine tRFs and let-7 in response to the low-protein diet, suggesting that similar diet-responsive pathways are present throughout the tract and providing technical replication of the fundamental epigenomic changes wrought by the low-protein diet.. Our finding of robust tRNA cleavage in the epididymis but not the testis raises the possibility that the abundant tRFs in the cauda sperm might ...
immune Uncategorized PA-824, Rabbit Polyclonal to C-RAF (phospho-Thr269). The blood-epididymis barrier (BEB) is formed by epithelial tight junctions mediating selective permeability from the PA-824 epididymal epithelium. the paracellular permeability had been examined by two strategies TER and FITC-Dextran-based tracer diffusion assays. Both assays soon add up to related outcomes indicating a time-dependent disruption from the BEB differentially for the three TGF? isoforms (TGF?3>TGF?1>TGF?2) inside a TGF?-recetor-1 kinase- and Smad-dependent way. The small junction proteins claudin-1 was discovered to be decreased by the procedure with TGF?s whereas occludin had not PA-824 been affected. Epididymal epithelial cells are mainly attentive to TGF?s PA-824 through the basolateral side recommending that TGF? may impact for the epididymal epithelium through the stroma cell tradition versions the knockdown of 1 of the claudins (1 -3 -4 or -7) led to dramatically reduced transepithelial electrical level ...
The epididymis plays a significant role as a quality control organ for long-term sperm storage, maturation, and fertilizing ability and perform filtration function to eliminate abnormal or residual spermatozoa by phagocytosis. However, the role of autophagy in spermiophagy during sperm storage in turtle epididymis still needs to be studied. In this study, we reported in vivo spermiophagy via the cellular evidence of lysosome engulfment and autophagy within the principal cells during sperm storage in the turtle epididymis. Using immunofluorescence, Lysosome associated membrane protein-1 (LAMP1) and microtubule-associate protein light chain 3 (LC3) showed strong immunosignals within the apical cytoplasm of epididymal epithelia during hibernation than non-hibernation. Co-immunolabeling of LAMP1 and LC3 was strong around the phagocytosed spermatozoa in the epididymal epithelia and protein signaling of LAMP1 and LC3 was confirmed by western blotting. During hibernation, ultrastructure showed
The epididymis (plural, epididymides) is a tightly coiled mass of thin tubes that carries sperm from the testes to the ductus deferens in the male reproductive system. Sperm matures as it pa
Objective: To evaluate the effect of the levels of IGF-Ⅰin the epididymis and the expression of IGF-Ⅰ in the testis of adult male rat after the administration of cyclophosphamide.Methods: Ninety-six male adult rats(8 weeks age)were divided into 6 groups.The doses given to the rats of the groups 1 to 5 were 10,20,40,80 and 100 mg/(kg·d),respectively.The remaining group was served as control.All those rats were sacrificed and IGF-I were quantitatively determined by ELISA techniques 2 and 4 weeks after the administration of the drug(by gastric fudge).Immunohistochemical SP technique was used to examine expression of IGF-I in rat testis. Results: The levels of cell factors(IGF-I)in the epididymis of the rats were gradually reduced with the increasing time and dose after administration of the drug.In the mean time the expression of IGF-I in the tissues of the testis of those rats were also gradually reduced.Conclusion: In the time of oligozoospermia/azoospermia induced by the administration of
Read Angiotensin II receptors: Localization of type I and type II in rat epididymides of different developmental stages, The Journal of Membrane Biology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
The epididymis is the organ with an elongated shape. It is attached to the near end of the testes, and is measuring for about 5.5 meters long, although its length could not be recognized due to its coiled feature. This part of the male reproductive organ keeps the sperm cells safe until its final stage of maturation- that is, the maturation of the tail.. Its head is known for its expanded portion that is clearly visible, and its body slowly fades out as it advances to the mid-section. The tail of the epididymis continues from the beginning of the ductus deferens. These sections are responsible for the storage of the maturing sperm cells until they are ready for ejaculation.. Normally, it takes 8 weeks for the male body to make mature sperm cells. ...
We report here a constitutive localization of PC in peritubular myoid cells and a dynamic profiling in epithelial cells throughout postnatal epididymal development. While PC are present at the apical pole of the undifferentiated epithelial cells from birth to puberty, they are absent from the apical pole of the epithelium in adults, where they appear exclusively associated with cytokeratin 5-positive basal cells. We determined that PC from epididymal cells are associated with polycystin 1 (PC1), polycystin 2 (PC2), and Gli-3 Hedgehog signaling transcription factor. No inter-individual variability was observed within each age group. ...
TY - JOUR. T1 - Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells. AU - Moule, SK. AU - Edgell, NJ. AU - Welsh, GI. AU - Diggle, TA. AU - Foulstone, EJ. AU - Heesom, KJ. AU - Proud, CG. AU - Denton, RM. PY - 1995. Y1 - 1995. M3 - Article (Academic Journal). VL - 311. SP - 595. EP - 601. JO - Biochemical Journal. JF - Biochemical Journal. SN - 0264-6021. ER - ...
Epididymis, Duct - Atrophy. This higher magnification of Figure 1 shows the scalloped outline of reduced epididymal ducts in a male F344/N rat from a subchronic study ...
Along each testicle is an epididymis. This stores sperm before they come into the seminal glands. If bacteria gets into the epididymis it can lead to inflammation. This is painful and has to be treated by a doctor, who will prescribe penicillin or other antibiotics.. ...
Purified Bovine Epididymis Lysate, Total Protein from Creative Biomart. Bovine Epididymis Lysate, Total Protein can be used for research.
Epididymis - What can cause the epididymis to be hard? Could be cyst. But it will not be hard Any testicular mass needs to be evaluated by trained professional (physician) to make sure is not a testicular tumor must see your doctor.
Purpose Spermatozoa undergo critical changes in structure and function during the epididymal transit. Our previous studies in the domestic cat demonstrated that incidence of cenexin-a key protein...
Every attempt was made to provide correct information and labelling, however any liability for eventual errors or incompleteness is rejected! ...
I am a 35 years old male. I got a lump in my right testicle operated last year. I am again developing a lump in the left testicle. |b|My epididymis is swelling, is hard and pains when pressed|/b|. My wife has a problem of white discharge from vagina. What do I need to do now?
Indoleamine 2,3-dioxygenase 1 (Ido1) is involved in the control of mouse caput epididymis immune environment - Jrad-Lamine, Aicha, Henry-Berger, Joelle, Cadet, Remi, Guiton, Rachel, Aitken, Robert J., Drevet, Joel R., Damon-Soubeyrand, Christelle, Saez, Fabrice, Kocer, Ayhan, Janny, Laurent, Pons-Rejraji, Hanae, Munn, David H., Mellor, Andrew L., Gharbi, Najoua ...
Indoleamine 2,3-dioxygenase 1 (Ido1) is involved in the control of mouse caput epididymis immune environment - Jrad-Lamine, Aicha, Henry-Berger, Joelle, Cadet, Remi, Guiton, Rachel, Aitken, Robert J., Drevet, Joel R., Damon-Soubeyrand, Christelle, Saez, Fabrice, Kocer, Ayhan, Janny, Laurent, Pons-Rejraji, Hanae, Munn, David H., Mellor, Andrew L., Gharbi, Najoua ...
Question - Infection on the epididymis. On antibiotics. Pus cells in urine. What is wrong?. Ask a Doctor about diagnosis, treatment and medication for Urinary tract infection, Ask a Urologist
Learn about length of epididymis topic of Biology in details explained by subject experts on vedantu.com. Register free for online tutoring session to clear your doubts.
Sperm from wild type and SP hyh (hyh) mice were collected from the cauda epididymidis, incubated under capacitation conditions for 1 h and stimulated with buffer (control), 10 µM progesterone (Pg) or 10 µM A23187 (A23187) for 15 min at 37°C.. PLoS ONE Alerts: New Articles. ...
The epididymis is at the back of the testicle, so i presume you indicate the lump is the head of the epididymis that is inflamed, it has a head a body and a tail that runs to almost 19 foot lengthy.. I had this two years in the past, i had it for approx 5 months in total one month serious and then 4 months on and off, and then a single day it just vanished and now i really feel absolutely nothing there, a whole lot of those antibiotics are undesirable information my friend, u dont need to have them for a simple non critical infection like this, people physicians only prescribe them due to the fact theyr striving to vindicate the bill their going to send you in a number of days, its like employing a sledgehammer to destroy an ant, also the epididymis is a quite intricate, tunnel-like spidery canal in which sperm mature and the infection can hide there from the antiobiotics in a crease and stay unchecked by the bodys immune technique for numerous weeks but it ought to ultimately be taken care of ...
Maturing sperm. Coloured freeze-fracture scanning electron micrograph (SEM) of healthy spermatozoa (sperm, pink) in the epididymis (green). Sperm cells are the male sex cells. They are produced in the testes and are responsible for fertilisation of the female ovum (egg). The epididymis is a long convoluted tube connecting the testes to the vas deferens. Here, a cross-section has been taken across two of its coils, making it appear as three separate tubes. Magnification: x300 when printed 10 centimetres wide. - Stock Image C002/0983
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Back in June 2012, I did some heavy lifting one day and that night I felt a sharp pain for a moment in my testicle. The next morning my right Testicle was swollen. I could not see a doctor for three weeks because none where accepting ne
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Epididymis tissue is commonly used in immunohistochemical detection. Immunohistochemistry (IHC) is an important means to be widely used to detect epididymis disease.
Bruce, Brendan; La Barbera, Andrew R.; Marsh, Karen (University of Cincinnati. College of Medicine; University of Cincinnati, 2007-09-28) ...
TESA and MESA are two different types of testicular biopsy. There are others too, each characterised as follows: MESA: Sperm aspiration from the epididymis
Case name: Histology Slides Case description: Case created date: 2015-04-24 16:46:11 Description: Scan date: 2015-09-11 09:34:29. Organ: Testis and epididymis (adult) L.S. (caput). Staining: n/a. Type: 2D Slide. Size: 1.49 GB. Open in application Open in browser ...
Protein name: TSCOT Aliases: Ly110 Substrates: unknown Transport type: N/D Tissue and cellular expression: Thymus, epididymis Subcellular expression: N/D Disease: N/D Locus: 9q32 Sequence ID: NP_149040.3, NM_033051.3 Gene ID: 57864 ...
Words That End In mis: agamis,amis,animis,camis,chiyogamis,cholesterolaemis,commis,degamis,dermis,elemis,endodermis,epidermis,epididymis,exodermis,exomis,fermis,filmis,gouramis,guramis,halloumis,haloumis,hypodermis,imprimis
Sperm maturation involves an intimate interaction between spermatozoa and the epididymal epithelium. Aspects of this relationship can be examined by co-incubating epididymal spermatozoa with epididymal epithelium in vitro. Plaques of epididymal epithelium from a variety of species (for example rodents, dogs, humans) can be maintained in culture medium supplemented with growth factors and androgens. When co-incubated with these epithelial cultures, immature epididymal spermatozoa undergo maturation changes that lead to the acquisition of progressive motility, zona binding and, in some instances, fertilizing capacity in vitro. The use of such co-culture techniques for the understanding of sperm maturation in vitro and in vivo is reviewed with reference to recent experiments.. ...
Looking for online definition of conical lobules of epididymis in the Medical Dictionary? conical lobules of epididymis explanation free. What is conical lobules of epididymis? Meaning of conical lobules of epididymis medical term. What does conical lobules of epididymis mean?
Here, the protein-coding genes expressed in the epididymis are described and characterized, together with examples of immunohistochemically stained tissue sections that visualize protein expression patterns of proteins that correspond to genes with elevated expression in the epididymis. Transcript profiling and RNA-data analyses based on normal human tissues have been described previously (Fagerberg et al., 2013). Analyses of mRNA expression including over 99% of all human protein-coding genes was performed using deep RNA sequencing of 172 individual samples corresponding to 37 different human normal tissue types. RNA sequencing results of 1 fresh frozen tissues representing normal epididymis was compared to 171 other tissue samples corresponding to 36 tissue types, in order to determine genes with elevated expression in epididymis. A tissue-specific score, defined as the ratio between mRNA levels in epididymis compared to the mRNA levels in all other tissues, was used to divide the genes into ...
Received: 21/Apr/2008, Accepted: 19/Jan/2009 Objective: Carrot (Daucus carota L.) is known to possess antifertility properties in female. However, according to Iranian traditional medicine, it can increase the potency in men. The aim of this study was to investigate the influence of carrot seed extract (CSE) on spermatogenesis, number and motility of sperms in cauda epididyme in male rats. Materials and Methods: Forty adult male rats were randomly divided into 5 groups: control group, groups receiving lowand high doses of CSE, animals that received high-dose of CSE with gentamicin, and a gentamicin only group. After 4 weeks treatment, fasting serum samples were obtained for the sex hormone analysis. Under anesthesia, testis, cauda epididymides and sperm ducts were dissected and sperm count, motility and cauda epididymis sperm reserves (CESR) were determined. Histopathological changes of testis were also studied to assess spermatogenesis. Data analysis was performed using one-way ANOVA followed by Tukey
Following freeze-fracture of the rat epididymis, a population of cells whose apical, but not baso-lateral, plasma membrane contains elongated intramembrane particles was found in the initial segment. From their size, shape and distribution, these cells are assumed to be the so-called apical cells of this segment. Apical cells also contain the enzyme, carbonic anhydrase which, together with the presence of rod-shaped particle on their membranes, permits their classification as mitochondria-rich cells, a specialized cell type found in some transporting epithelia. On the basis of these observations, we suggest that the apical cells may play a role in fluid and/or electrolyte transport in the initial segment of the epididymis. ...
Medical Science Research 1997; 25 (2): 97-100. Fluoride toxicity in the testis and cauda epididymis of guinea pig and reversal by ascorbate. Chinoy NJ, Patel BC, Patel DK, Sharma AK.. Author Address: Zoology Dep., Sch. Sciences, Gujarat Univ., Ahmedabad 380009, India. Effects of sodium fluoride (NaF) (30 mg kg-1 body weight) and ascorbic acid ingestion along with sodium fluoride for 30 days each were studied to evaluate its possible role as an ameliorative agent on functions of reproductive organs and spermatozoa of the fluorotic guinea pig. The cauda epididymal spermatozoa were highly sensitive to the effects of sodium fluoride as their structural and metabolic alterations led to marked decreases in their motility, live:dead ratio and sperm mitochondrial activity index but increases in sperm abnormalities and alterations in sperm membrane phospholipids, particularly phosphatidylinositol and phosphatidyl serine. The activities of ATPase and succinate dehydrogenase as well as glutathione levels ...
A 31-year-old man with recurrent testicular torsion and infertility was found to have a fusional anomaly of the epididymis on scrotal exploration in which only the head of epididymis was attached to the testis, while the body and tail were completely free. He had bilateral orchidopexy, which relieved pain and recurrent torsion. He was then referred for fertility treatment. Literature search has shown that infertility is more associated with congenital anomalies of the epididymis and not with recurrent torsions ...
The alternative to surgical reversals or reconstruction / repair is sperm retrieval by needle aspiration, and the techniques commonly employed, are PESA (Percutaneous Epididymal Sperm Aspiration) and TSE (Testicular Sperm Extraction). Most men are familiar with their soft and squishies, but know little of the epididymis; sausage-like sacs attached behind each testicle that contain meters of tightly coiled miniscule tubes and canals. In essence, they connect the testicles bilaterally to the vas deferens, which constitute the main pipeline of the males reproductive tract. The epididymis is the subject of controversy, but it can be safely said that they act to accumulate and transport sperm. In the normal male, it takes 6 weeks for sperm to travel their path from genesis in the testicles to ejaculation, and a large part of that time is spent in the epididymis. The controversy though is intriguing. Some specialists believe that the very fine hairs within the epididymis literally stroke the sperm ...
Introduction: Ovarian cancer is one of the most common malignancies in women and the fifth cause of cancer-related deaths in women worldwide. Contrary to the challenges in developing new clinical markers using the conventional methods, recent advances in genomics and proteomics have led to identification of candidate and promising biomarkers for the diagnosis of ovarian cancer. Human epididymis protein 4 (HE4) is such a marker that has recently been reported to correlate with recurrence or progression of epithelial ovarian cancer. The purpose of this study was to measure the expression level of HE4 gene in women with ovarian cancer. Methodology: We evaluated and compared paraffin-embedded tissue samples of 20 ovarian cancer patients with 10 samples from healthy individuals. RNA was initially extracted from the samples and cDNA was synthetized. Gene expression level was then measured using real-time polymerase chain reaction (PCR). Results: Our results demonstrated that HE4 gene expression
Adult male rats were injected with TSAA-291 (16 beta-ethyl-17 beta-hydroxyestr-4-en-3-one), a steroidal antiandrogen, daily for 30 days at two doses, viz., 10.0 and 25.0 mg/kg. The treatment caused a dose-dependent reduction in the weights of testis, epididymis, and other accessory sex glands. In the animals that received the high dose, 50% of the rats showed spermatogenic arrest in about 20% of the seminiferous tubules and Leydig cell morphology was normal. The levels of glycerylphosphorylcholine and sialic acid were significantly reduced in the cauda epididymis of all the treated rats. There was a reduction in the number of motile spermatozoa in the cauda epididymis of rats treated with high dose of the antiandrogen. This was accompanied by a reduced number of females exhibiting spermatozoa in their vaginal smears. A combination treatment of the antiandrogen and androgen appears to be a promising approach for fertility regulation in the male.
We appreciate the opportunity to discuss our paper ( Sutovsky et al., 2001a) and thank Cooper et al. for their respected opinion. Our work provides morphological and biochemical evidence that ubiquitin, a universal proteolytic marker that is also implicated in endocytosis, is found predominantly on the surface of defective spermatozoa during and after, but not prior to, their passage through the epididymis. Since the covalent ligation of ubiquitin serves as a selective, substrate-specific signal for proteolytic degradation ( Laney and Hochstrasser, 1999), we suggested the term epididymal sperm quality control. The presence of ubiquitin in human sperm ( Sutovsky et al., 2001b), seminal plasma ( Lippert et al., 1993) and epididymal epithelium ( Fraile et al., 1996; Santamaria et al., 1993) has been shown previously, and we performed an extensive set of control experiments to test the specificity of our anti-ubiquitin antibodies. Other proteins including clusterin ( Ibrahim et al., 2000) and ...
Two enzymes are involved in the polyol pathway: an aldose reductase that reduces glucose in sorbitol followed by its oxidation in fructose by sorbitol dehydrogenase. It has been previously shown that both enzymes are presented in the bovine epididymis, where they are associated with membranous vesic …
This study was designed to study the capacitation of caudal spermatozoa in vitro by different levels of heparin, estrogen for in vitro fertilization (IVF) in the Iraqi local sheep. Results of sperm capcitation (massive motility percentage) by applying three levels of heparin (50, 100, 150) IU in relation to breeding season showed no significant differences during breeding season with the three levels, which were (82.23 ± 0.58), While results by applying the higher level of heparin (150) IU out of breeding season showed significantly (P,0.05) more and active motility Which were (62.07 ± 0.62) than the other levels (56.85 ± 0.61). At the same time applications result of three estrogen levels (20, 40, 60) mg on sperm capcitation showed Positive relationship between concentrations and (massive motility percentage), which showed the highest concentration gave the best results during and out of breeding season (87.20 ± 0.60) and (65.86 ± 0.62) respectively. with significant differences (P,0.05) ...
The epididymis is tube-like cavity located around the scrotum, a part of the male reproductive system. The sperm moves into and collects in the epididymis before it moves further into the vas deferens.. Epididymal cysts, commonly called scrotal cysts refer to fluid-filled sacs that occur in the tube-like epididymis. In most cases, the cyst is a benign one. They do not cause any pain in the patient and only cause some mild discomfort. They are also not associated to cancer in any way. These cysts occur at the head of the epididymis, which is just above the testicles. They can even be found by self-inspection, or the doctor may find them through a simple physical inspection. However, these cysts or lumps are not to be compared with cancer lumps, which occur within, rather than on, the testicles.. The most common and viable treatments in metro cities like Mumbai for scrotal cysts is the scrotal cyst removal surgery. Other forms of scrotal cyst removal treatment in Mumbai include using a needle to ...
BioAssay record AID 36841 submitted by ChEMBL: Inhibition of the enzyme alpha-L-fucosidase from bovine epididymis was determined at 1 mM concentration of the compound; No inhibition.
Bekijk Stockfoto van Crosssection Through The Wall Of The Epididymis Showing Long Microvilli On The Surface Of The Pseudostratified Epithelium And The Underlying Layer Of Smooth Muscle. Ga voor hoogwaardige fotos met een hoge resolutie naar Getty Images.
Expression of PPP5C (PP5, PPP5) in epididymis tissue. Antibody staining with HPA029065, HPA056933 and CAB022641 in immunohistochemistry.
Histological comparison of epididymides of 6-mo-old MMTV-VEGF transgenic and WT control mice (A-H), and localization of expression of the VEGF transgene and
Epididymis[edit]. Main article: Epididymis. The epididymis is a long whitish mass of tightly coiled tube. The sperm that are ... long that starts from the epididymis to the pelvic cavity. It carries the spermatozoa from the epididymis to ejaculatory duct. ... During passage via the epididymis, the sperm undergo maturation and are concentrated by the action of ion channels located on ... and CFTR in segments of the mammalian epididymis". Journal of Molecular Histology. 50 (2): 141-154. doi:10.1007/s10735-019- ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... In the male the duct persists, and forms the tube of the epididymis, the vas deferens and the ejaculatory duct, while the ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... which is sometimes found in front of the spermatic cord above the head of the epididymis. In the female the mesonephric bodies ...
e. Caput epididymis. g. The gubernaculum. i. Lower part of the intestine. m. Müllerian duct, the upper part of which remains as ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, ...
Epididymis. Main article: Epididymis. The epididymis, a whitish mass of tightly coiled tubes cupped against the testicles, acts ... long that starts from the epididymis to the pelvic cavity. It carries the spermatozoa from the epididymis to ejaculatory duct. ... a portion of the embryonic mesonephric duct adjacent to the testis becomes attached and convoluted informs the epididymis. ...
It mainly presents in the genital tract, in regions such as the testis and epididymis. Because of this, researchers had a ... "Adenomatoid tumor of the epididymis". Archived from the original on 2007-06-15. Retrieved 2007-12-15. "Adenomatoid Tumor - ...
While in the epididymis the spermatozoa gain motility and become capable of fertilization. However, transport of the mature ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells with the aid of ... The initial stages occur within the testes and progress to the epididymis where the developing gametes mature and are stored ... Maturation occurs in the epididymis. The location [Testes/Scrotum] is specifically important as the process of spermatogenesis ...
Joseph A, Shur BD, Hess RA (2011). "Estrogen, efferent ductules, and the epididymis". Biol Reprod. 84 (2): 207-217. doi:10.1095 ... and lack of spermatozoa in the epididymis has been observed in conjunction with defects in MCC development. "Geminin coiled- ...
"Torsion of the Appendices and Epididymis". Medscape. Updated: Oct 20, 2016. Citing: Nason, Gregory J; Tareen, Farhan; ...
Eylar EH, Murakami M (1966). "beta-Aspartyl-N-acetylglucosaminidase from epididymis". Methods Enzymol. Methods in Enzymology. 8 ...
Whilst in the epididymis, they acquire motility. However, transport of the mature spermatozoa through the remainder of the male ... The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells, with the aid of ...
"Testis and epididymis - Sertoli cell tumor, NOS". www.pathologyoutlines.com. Retrieved 2016-12-06. Leach S, Heatley JJ, Pool RR ...
Epididymitis occurs when there is inflammation of the epididymis (a curved structure at the back of the testicle).[5] This ...
In the male the duct persists, and forms the tube of the epididymis, the vas deferens and the ejaculatory duct, while the ... t', together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen ... which is sometimes found in front of the spermatic cord above the head of the epididymis. ...
Backpressure from blockage of the vas deferens causes a rupture in the epididymis, called an "epididymal blowout", in 50% of ... When pain in the epididymides is the primary symptom, post-vasectomy pain syndrome is often described as congestive ... There is a noticeable enlargement of the epididymides in vasectomized men. This is probably due to increased backpressure ... One study using ultrasound found that the epididymides of patients suffering from post-vasectomy pain syndrome were enlarged ...
402-. ISBN 978-0-323-08619-6. Robaire B, Henderson NA (May 2006). "Actions of 5alpha-reductase inhibitors on the epididymis". ... epididymides, skin, hair follicles, liver, kidneys, and brain, among others. By inhibiting 5α-reductase and thus preventing DHT ... and decreases motility and normal morphology of spermatozoa in the epididymis. Neurosteroids like 3α-androstanediol (derived ...
They also form the epididymis and the paradidymis. The sperm differentiate inside the seminiferous tubules, then swim down ...
Caccamo D, Socias M, Truchet C (1991). "Malignant Brenner tumor of the testis and epididymis". Arch. Pathol. Lab. Med. 115 (5 ...
Expression of ADAM7 is higher in the head (Caput) of the epididymis and decreases in cells towards the distal epididymis. ADAM7 ... Secretion in this manner is an apocrine secretion in which apical blebs containing a portion of the epididymis cell are ... ADAM7 is secreted by epididymis cells and transferred to the maturing sperm's surface. As determined through mouse gene knock- ... ADAM7 is synthesized in epididymis cells and transferred to the membrane of immature sperm cells as they traverse the ...
A second tube, the ductulus aberrans superior, occurs in the head of the epididymis; it is connected with the rete testis. This ... Occasionally it is found unconnected with the epididymis. ... connected with the lower part of the canal of the epididymis, ...
Section of epididymis. Connective tissue (blue) is seen supporting the epithelium (purple) ...
The contractions rapidly force sperm out of each epididymis. They also force the contents of seminal vesicles and the prostate ...
The second part of the duct system is the vas deferens, a muscular tube that begins at the lower end of the epididymis.[page ... The first part of this system is the epididymis. The testicles converge to form the seminiferous tubules, coiled tubes at the ...
Epididymis are medium-sized, discoid, tightly packed masses of ducting standing upright on either side of the atrium and ... Vas deferens is thin ducts running from epididymis posteriorly. Testisacs is ovoid, approximately 1.5 times the size of ovisacs ...
Epididymitis, a painful inflammation of the epididymis or epididymides frequently caused by bacterial infection but sometimes ... Tail of epididymis; K.) Body of epididymis; L.) Mediastinum; M.) Vas deferens. ... Spermatocele, a retention cyst of a tubule of the rete testis or the head of the epididymis, called ... A.) Blood vessels; B.) Head of epididymis; C.) Efferent ductules; D.) Seminiferous tubules; E.) Parietal lamina of tunica ...
Head of epididymis, 9b. Body of epididymis, 9.c Tail of epididymis,10. Vas deferens, 11a. Tunica vaginalis (parietal lamina), ...
Fröhlich O, Po C, Murphy T, Young LG (2000). "Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2 ... Fröhlich O, Po C, Young LG (April 2001). "Organization of the human gene encoding the epididymis-specific EP2 protein variants ... This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins ... "Vasectomy influences expression of HE1 but not HE2 and HE5 genes in human epididymis". Journal of Andrology. 25 (1): 30-43. doi ...
Infection causes severe inflammation of the epididymis, particularly the tail. Brucella ovis, reviewed and published by Wikivet ...
Pseudostratified columnar epithelia with stereocilia are located in the epididymis. Stereocilia of the epididymis are not cilia ...
The sperm that are produced in the seminiferous tubules flow into the epididymis. During passage via the epididymis, the sperm ... long that starts from the epididymis to the pelvic cavity. It carries the spermatozoa from the epididymis to ejaculatory duct. ... The epididymis is a long whitish mass of tightly coiled tube. ... and CFTR in segments of the mammalian epididymis". Journal of ... a portion of the embryonic mesonephric duct adjacent to the testis becomes attached and convoluted informs the epididymis. ...
... it transports sperm from the epididymis in anticipation of ejaculation. In humans, the vas deferens routes up from the testicle ...
Epididymis. Adult human testicle with epididymis: A. Head of epididymis, B. Body of epididymis, C. Tail of epididymis, and D. ... The epididymis (/ɛpɪˈdɪdɪmɪs/; plural: epididymides /ɛpɪdɪˈdɪmədiːz/ or /ɛpɪˈdɪdəmɪdiːz/) is a tube that connects a testicle to ... The epididymis can be divided into three main regions: *The head (Latin: caput). The head of the epididymis receives ... Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis. In ...
Epididymis (fi); Epididymis (lt); 정소상체 (ko); vescile (en); البربخ, Epididymis (ar); epididymis (cs); எபிடைமிஸ், விந்தக ... Epididymis (sr); Epididymis, Epididimis (bs); 副睾丸, 睾上体 (ja); Najądrza (pl); epididimoj (eo); Bitestiklar, Epididymis (sv); ... Epididymis (es); Canal épididymaire, Epididyme (fr); Epididymis, Dosjemenik (hr); Эпидидимис (ru); Epididymis (de); Epididimo ( ... Epididymis (tl); 부고환 (ko); epididymis (sco); Najądrze (pl); bitestikkel (nn); bitestikkel (nb); Xaya artımı (az); Придаток ...
Epididymis definition, an elongated organ on the posterior surface of a testis that stores sperm while they mature and ... epididymis. Historical Examples. of epididymis. *. The epididymis referred to above, consists of a mass of coiled tubes and ... epididymis. in Medicine. epididymis. [ĕp′ĭ-dĭd′ə-mĭs]. n. pl. ep•i•did•y•mi•des (-mĭ-dēz′). *A long, narrow, convoluted tube in ... epididymis. epididymis. noun plural -didymides (-dɪˈdɪmɪˌdiːz). *anatomy a convoluted tube situated along the posterior margin ...
A varicocele is a bit like an area of varicose veins around the epididymis. These distended veins slowly enlarge over time, and ... My epididymis is still growing. A varicocele is a bit like an area of varicose veins around the epididymis. These distended ... A varicocele is a bit like an area of varicose veins around the epididymis. These distended veins slowly enlarge over time, and ... I say testicle, but I actually mean the thing that runs along the back of the testicle - is it the epididymis? ...
Ligament of epididymis may refer to: Inferior ligament of epididymis Superior ligament of epididymis This disambiguation page ... lists articles associated with the title Ligament of epididymis. If an internal link led you here, you may wish to change the ...
encoded search term (Testes and Epididymis Anatomy) and Testes and Epididymis Anatomy What to Read Next on Medscape ... this layer invests a slitlike recess between the body of the epididymis and the testis that is called the sinus of epididymis. ... The epididymis is a comma shaped, elongated structure composed of a single, fine tubular structure estimated up to 6 meters ( ... Two vestigial embryonic structures of no known physiologic function are often found on the testis and epididymis, as follows:. ...
It has been previously shown that both enzymes are presented in the bovine epididymis, where they are associated with ... Polyol pathway in human epididymis and semen J Androl. Mar-Apr 2006;27(2):233-9. doi: 10.2164/jandrol.05108. Epub 2005 Nov 8. ... In the present study, polyol pathway was investigated in semen and along the epididymis in humans in order to determine if ... It has been previously shown that both enzymes are presented in the bovine epididymis, where they are associated with ...
Epididymis. Adult human testicle with epididymis: A. Head of epididymis, B. Body of epididymis, C. Tail of epididymis, and D. ... The epididymis is the part of the human male reproductive system. It is the tube that holds the testicles in place. It ... Sperm made in the testis go into the head (caput) of the epididymis, go through the body (corpus) and stop at the tail (cauda ... Jones R (1999). "To store or mature spermatozoa The primary role of the epididymis". Int J Androl. 22 (2): 57-67. doi:10.1046/j ...
Epididymis - Hypospermia. A reduced number of sperm in the epididymis in a male F344/N rat from a subchronic study. ... Epididymis - Hypospermia. Higher magnification of Figure 1. A reduced number of sperm in the epididymis in a male B6C3F1 mouse ... Epididymis - Hypospermia. A reduced number of sperm in the epididymis in a male B6C3F1 mouse from a subchronic study. ... Actions of toxicants on the structure and function of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire B ...
Epididymis secretory sperm binding proteinImported. ,p>Information which has been imported from another database using ... tr,A0A384MTX4,A0A384MTX4_HUMAN Epididymis secretory sperm binding protein OS=Homo sapiens OX=9606 PE=2 SV=1 ...
... specimen consisting of a bisected testis and epididymis showing multiple foci of caseating tuberculosis in the epididymis with ... A 1937 surgical resection specimen consisting of a bisected testis and epididymis showing multiple foci of caseating ... A 1937 surgical resection specimen consisting of a bisected testis and epididymis showing multiple foci of caseating ... tuberculosis in the epididymis with a small hydrocoele of the tunica vaginalis. ...
Epididymis, Duct - Atrophy. Decreased diameter of empty ducts in the body and tail of the epididymis in a male F344/N rat from ... Actions of toxicants on the structure and function of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire B ... Androgenic regulation of the structure and functions of the epididymis. In: The Epididymis: From Molecules to Clinical (Robaire ... If both epididymides are involved, the diagnosis should be indicated as bilateral and the severity based on the more severely ...
... a rat epididymis tissue section is presented that was labeled with the fluorophore Texas Red conjugated to wheat germ ... Rat Epididymis Tissue Section. In the digital image above, a rat epididymis tissue section is presented that was labeled with ...
Torsion of the appendix testis and appendix epididymis means that this tissue of the testis has twisted and cut off its own ... The appendix epididymis is a small appendage located at the top of the epididymis (tube-shaped structure that connects to the ... Pediatric Torsion of the Appendix Testis and Appendix Epididymis. Torsion of the appendix testis and appendix epididymis occurs ... Pediatric Torsion of the Appendix Testis and Appendix Epididymis Pediatric Torsion of the Appendix Testis and Appendix ...
1: Epididymis. 2: Head of epididymis. 3: Lobules of epididymis. 4: Body of epididymis. 5: Tail of epididymis. 6: Duct of ... The epididymis is part of the human male reproductive system and is present in all male mammals. It is a narrow, tightly-coiled ... The epididymis is one of only two regions of the body to have stereocilia (the inner ear being the other.)[2] ... Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis. ...
The Novel Epididymis Specific Beta Galactosidase Like Gene Glb1l4 Is... Identification of a Transcription Factor, BHLHB8, ... Differences in pKi values in caput and cauda epididymis from immature and adult animals also suggested that the relative amount ... These changes were followed by a progressive increase in rat body weight and in caput and cauda epididymis relative weight. ... We have characterized the expression of α1-adrenoceptor in epididymis from rats in different stages of sexual maturation: 40 ( ...
ICD-9 code 016.4 for Tuberculosis of epididymis is a medical classification as listed by WHO under the range - TUBERCULOSIS ( ... Tuberculosis of epididymis (016.4). ICD-9 code 016.4 for Tuberculosis of epididymis is a medical classification as listed by ...
On the epididymis and its role in the development of the fertile ejaculate.. Turner TT1. ...
What is Appendix epididymis? Meaning of Appendix epididymis medical term. What does Appendix epididymis mean? ... Looking for online definition of Appendix epididymis in the Medical Dictionary? Appendix epididymis explanation free. ... appendix epididymis. a small, piriform body attached to the head of the epididymis that is a remnant of the blind cranial ... Related to Appendix epididymis: Appendix testis. appendix. [ah-pen´diks] (pl. appen´dices, appendixes) (L.) 1. a slender ...
Publications about Experts and Doctors on epididymis in Germany ... Cooper T. The epididymis, cytoplasmic droplets and male ... Yeung C, Breton S, Setiawan I, Xu Y, Lang F, Cooper T. Increased luminal pH in the epididymis of infertile c-ros knockout mice ... Damm O, Cooper T. Maturation of sperm volume regulation in the rat epididymis. Asian J Androl. 2010;12:578-90 pubmed publisher ... Ellerbrock K, Pera I, Hartung S, Ivell R. Gene expression in the dog epididymis: a model for human epididymal function. Int J ...
... , Rachel Mngu-suur K, Hambolu Joseph O, ... The epididymis was observed to be highly convoluted at the cranial aspect of each testis as the catput epididymis, the medial ... The epididymis was composed of tightly packed ducts with the head of the epididymis consisting of the most packed ducts as ... Spermatozoa are known to spend a longer time in the catput epididymis and a shorter period of time in the caudal epididymis as ...
... Adv Exp Med Biol. 1991;286:19-32. doi: ... In all, this circumstantial evidence makes it seem possible that the human epididymis as well as the testis often exists in a ... Further effects of deep body temperature on the epididymis are seen in significantly faster (rabbit) sperm transport through it ... Selective imposition of abdominal temperature on the epididymis alone does not suppress sperm maturation there, and bilaterally ...
Epididymis, Human. Hematoxylin & Eosin. Section. Each. Retrieving. The minimum order for this item is . ...
Home › Q & A › Questions › I had epididymis had surgery.... I had epididymis had surgery had left testicle removed, prior pain ...
Diagnostic Test: Human epididymis protein 4 Human epididymis protein 4 serum level in predicting persistent proteniuria ... Human Epididymis Protein 4 in Women With Severe Preeclampsia / HELLP Syndrome. The safety and scientific validity of this study ... Prognostic Value of Human Epididymis Protein 4 (HE4) for Persistent Proteinuria in Women With Severe Preeclampsia / HELLP ...
Epididymis shares the largest number of genes with testis. KIAA1210 is group enriched in testis, epididymis and seminal vesicle ... Epididymis function. The epididymis is a highly coiled, single tubular structure that connects each testicle to the vas ... Genes shared between the epididymis and other tissues. There are 88 group enriched genes expressed in the epididymis. Group ... Protein expression of genes elevated in epididymis. In-depth analysis of the elevated genes in epididymis using antibody-based ...
b,My epididymis is swelling, is hard and pains when pressed,/b,. My wife has a problem of white discharge from vagina. What do ... Why does my epididymis pain when pressed?. Answered by: Prof B Krishna Rau , Professor and Head of Dept. of Surgery,. Sri ... My epididymis is swelling, is hard and pains when pressed. My wife has a problem of white discharge from vagina. What do I need ... Home » Frequently asked Questions on Health » Why does my epididymis pain when pressed? ...
epididymis answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android ... epididymis is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please log in or purchase a ... "Epididymis." Tabers Medical Dictionary, 24th ed., F.A. Davis Company, 2021. Tabers Online, www.tabers.com/tabersonline/view/ ... Tabers-Dictionary/740004/all/epididymis. Epididymis. In: Venes DD, ed. Tabers Medical Dictionary. F.A. Davis Company; 2021. ...
Zyagen Labs Mouse CD1 epididymis cDNA is a full-length first strand cDNA synthesized from high quality CD1 Mouse epididymis ... Mouse CD1 epididymis cDNA is a full-length first strand cDNA synthesized from high quality CD1 Mouse epididymis tissue RNA by ...
  • plural: epididymides /ɛpɪdɪˈdɪmədiːz/ or /ɛpɪˈdɪdəmɪdiːz/) is a tube that connects a testicle to a vas deferens in the male reproductive system. (wikipedia.org)
  • During ejaculation, sperm flow from the cauda epididymis (which functions as a storage reservoir) into the vas deferens where they are propelled by the peristaltic action of muscle layers in the wall of the vas deferens, and are mixed with the diluting fluids of the prostate, seminal vesicles, and other accessory glands prior to ejaculation (forming semen). (wikipedia.org)
  • The visceral layer of the tunica vaginalis testis is closely applied to the testis, epididymis, and ductus deferens. (medscape.com)
  • he mammalian epididymis is an exceptionally long, convoluted ductal system that serves to connect the ductuli efferentes, which drain the testes, to the ductus deferens. (pulsus.com)
  • Epididymis is an elongated lump between testis and vas deferens , consists of a 15-20 feet long convoluted tubules for sperms to pass and mature (in10-12 days), and it usually hugs / attaches right onto the posterior aspect of testis. (healthtap.com)
  • This a normal structure of the male reproductive system ( coiled tube that connect the testes to the vas deferens ), sperm goes through the epididymis. (healthtap.com)
  • Efferent ducts in the head of epididymis unite to form a single duct in the body and tail region (globus minor), which continues as the ductus deferens . (radiopaedia.org)
  • The male ACI rat has a congenital Wolffian duct defect manifested by unilateral agenesis of the kidney, ureter, seminal vesicle, ductus deferens, and most of the epididymis. (semanticscholar.org)
  • Conclusion: The existing data indicate that activins play a complex role in controlling inflammation and immunity in the epididymis and vas deferens. (monash.edu)
  • The vas deferens, which is also known as the sperm duct, is a thin tube approximately 30 centimetres (0.98 ft) long that starts from the epididymis to the pelvic cavity. (wikipedia.org)
  • The tail of the epididymis continues from the beginning of the ductus deferens . (medicalterms.info)
  • In the male the duct persists, and forms the tube of the epididymis, the vas deferens and the ejaculatory duct, while the seminal vesicle arises during the third month as a lateral diverticulum from its hinder end. (wikipedia.org)
  • Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis . (wikipedia.org)
  • The head of the epididymis measures approximately 5-12 mm in length and may have a small projection called the appendix of the epididymis 3 . (radiopaedia.org)
  • Sperm parameters and epididymis function in transgenic rats overexpressing the Ca2+-binding protein regucalcin: a hidden role for Ca2+ in sperm maturation? (ualg.pt)
  • It has been previously shown that both enzymes are presented in the bovine epididymis, where they are associated with membranous vesicles called epididymosomes. (nih.gov)
  • This book sheds light on the histological and histochemical characteristics of the bovine epididymis. (abebooks.co.uk)
  • A major part of this book was concerned with the prenatal development of the bovine epididymis. (abebooks.co.uk)
  • Bovine Epididymis Total Protein (protein lysate) is isolated from freshly harvested tissues of single healthy normal donor. (creativebiomart.net)
  • c.1600, "fleshy mass at the back of the testicles," Modern Latin, literally "that which is on the testicles," from Greek epididymis , a word probably coined by Greek anatomist Herophilus (c.300 B.C.E.) from epi "on" (see epi- ) + didymos "testicle," literally "double, twofold" (adj. (dictionary.com)
  • I say testicle, but I actually mean the thing that runs along the back of the testicle - is it the epididymis? (netdoctor.co.uk)
  • And you are also right that as this is at the back of your testicle, it probably involves the epididymis. (netdoctor.co.uk)
  • The appendix epididymis is a small appendage located at the top of the epididymis (tube-shaped structure that connects to the testicle). (childrens.com)
  • It is a swollen blood vessel from the testicle that appears or feels like an enlarged epididymis. (wikidoc.org)
  • I had epididymis had surgery had left testicle removed, prior pain was unbearable, still trying to? (drugs.com)
  • Epididymis is part of the conducting system , and in situated one on either side just above and mainly behind each testicle. (healthtap.com)
  • The pain seems to be where the testicle meets the epididymis and then can be through a vein in my inner thigh. (askthedoctor.com)
  • Along each testicle is an epididymis . (guttogjente.no)
  • The epididymis is covered by a two layered pseudostratified epithelium . (wikipedia.org)
  • Cross-section through the wall of the epididymis showing long microvilli on the surface of the pseudostratified epithelium and the underlying layer of smooth muscle. (gettyimages.ca)
  • The epididymal head overhangs the upper pole of the testis, receives the seminal fluid from the ducts of the testis (which pierce the upper portion of the mediastinum), then allows the passage of the sperm into the distal portion of the epididymis. (medscape.com)
  • Epididymides were dissected from adult cat testes to assess the presence and localization of cenexin in testicular tissues and each epididymal segment (caput, corpus, and cauda) via immunofluorescence, Western blot, and mass spectrometry. (springer.com)
  • Our study is unique in the aspect of systematic identification of novel epididymal genes and should be a firm basis for future investigation into molecular mechanisms underlying sperm maturation in the epididymis. (biomedcentral.com)
  • Although spermiophagy normally is not seen in the epididymis of all mammals thus far investigated, under certain conditions such as after obstruction or during advanced ageing, spermatozoa can be rarely seen in the cells of the epididymal epithelium. (biologists.org)
  • Evidence has also accumulated, indicating that locally formed angiotensin II from the rat epididymis may play a paracrine and/or autocrine role in regulating epididymal electrolyte and fluid transport. (deepdyve.com)
  • The present finding of the differential patterns of angiotensin II receptor immunoreactivity in three different stages of the rat epididymis may reflect the fine tuning of rat epididymal function by angiotensin II, acting as a paracrine or autocrine agent, during the course of development. (deepdyve.com)
  • Although the establishment of a calcium (Ca(2+)) gradient along the epididymis has been described, its direct effects on epididymal function remain poorly explored. (ualg.pt)
  • Tissue incubation with (45)Ca(2+) showed also that epididymis of Tg-RGN displayed a diminished rate of Ca(2+)-influx, indicating unbalanced Ca(2+) concentrations in the epididymal lumen. (ualg.pt)
  • The absence of IDO also increased the tryptophan content of the caput epididymis and generated a parallel increase in caput epididymal protein content as a consequence of deficient proteasomal activity. (uni-regensburg.de)
  • Nicander L, Malmqvist M. Ultrastructural observations suggesting merocrine secretion in the initial segment of the mammalian epididymis. (springer.com)
  • The mammalian epididymis is a segmented organ comprised of a single highly convoluted tubule divided into four regions: the initial segment, caput, corpus, and cauda regions. (biomedcentral.com)
  • The Mammalian Epididymis. (biologists.org)
  • Intriguingly, IDO is constitutively and highly expressed in the mammalian epididymis in contrast to most other tissues where IDO is induced by proinflammatory cytokines, such as interferons. (uni-regensburg.de)
  • To gain insight into the role of IDO in the physiology of the mammalian epididymis, we studied both wild type and Ido1(-/-)-deficient mice. (uni-regensburg.de)
  • Although these three anatomical regions of the epididymis are easily identified in most adult male mammals [ 2 ], histological and ultrastructural segmentation of this organ varies among the different species of mammals [ 2 ]. (pulsus.com)
  • Sperm quality in the Caput, corpus, and cauda regions of the epididymis of healthy and sexually mature Landrace boars was studied. (eurekamag.com)
  • The incidence of spermatozoa with the head detached from the tail remained stable in the first two regions of the epididymis, increasing notably in the cauda. (eurekamag.com)
  • Moreover, the immune cell subsets and immunological responses between different regions of the epididymis vary considerably. (monash.edu)
  • Spermatozoa formed in the testis enter the caput epididymis, progress to the corpus, and finally reach the cauda region, where they are stored. (wikipedia.org)
  • The head of the epididymis receives spermatozoa via the efferent ducts of the mediastinium of the testis . (wikipedia.org)
  • This luminal compartment of the epididymis stores the spermatozoa until ejaculation. (pulsus.com)
  • Not only does the epididymis preserve the spermatozoa, it also prepares the spermatozoa for fertilization by providing the essential requirements in terms of temperature, oxygen tension, pH and an available energy substrate [ 1 ]. (pulsus.com)
  • Further effects of deep body temperature on the epididymis are seen in significantly faster (rabbit) sperm transport through it, and a reduction in the time required for capacitation of (hamster) spermatozoa, in vitro and in vivo. (nih.gov)
  • Chemical and thermal effects on the viability and motility of spermatozoa from the turtle epididymis. (cdc.gov)
  • The viability and motility of spermatozoa harvested from the epididymides of turtles were estimated to elucidate properties that might enable them to be stored over long periods of time. (cdc.gov)
  • After clearing the epididymis with multiple ejaculations, and after about 2 weeks of abstinence spermatozoa have been shown to appear in the urine . (healthtap.com)
  • The objectives of the study were to (1) characterize mechanisms involved in transferring key factors-using the cenexin as a marker-between the epididymis and maturing sperm cells and (2) demonstrate the impact of such mechanisms on the acquisition of functional properties by spermatozoa. (springer.com)
  • The storage conditions were optimized by storing the mouse epididymides at 4 C in mineral oil or in the mouse body for up to 4 days after death, and the retrieved spermatozoa were used to fertilize fresh oocytes. (nii.ac.jp)
  • Spermatozoa retrieved from epididymides stored in mineral oil were then used to fertilize fresh and vitrified oocytes with or without ZIP treatment. (nii.ac.jp)
  • therefore, the spermatozoa extracted from the tail of the epididymis is capable of fertilizing eggs. (sa-boergoats.com)
  • Maturation of spermatozoa, including development of motility and the ability to fertilize the oocyte, occurs during transit through the microenvironment of the epididymis. (biomedcentral.com)
  • For it to be valid, two important points need to be established: a loss of sperm in the epididymis and the removal of abnormal spermatozoa by its epithelium. (biologists.org)
  • presents unconvincing evidence for removal of defective spermatozoa by the normal epididymis and that the data certainly cannot be interpreted as a role for the epididymis in control of sperm quality. (biologists.org)
  • Studies on resorption of ( 3 H) thymidine-labeled spermatozoa in the epididymis. (biologists.org)
  • Testes produce spermatozoa that transit through and are stored in the epididymis where they acquire their fertilising capacities. (inserm.fr)
  • The epididymis plays a significant role as a quality control organ for long-term sperm storage, maturation, and fertilizing ability and perform filtration function to eliminate abnormal or residual spermatozoa by phagocytosis. (aging-us.com)
  • These data provide support for IDO playing a hitherto unsuspected role in sperm quality control in the epididymis involving the ubiquitination of defective spermatozoa and their subsequent removal. (uni-regensburg.de)
  • It carries the spermatozoa from the epididymis to ejaculatory duct. (wikipedia.org)
  • The tunica vaginalis testis (a remnant of the processus vaginalis) envelopes the testis in a double layer, except at the superior and posterior borders, where the spermatic cord and epididymis adhere to the testes. (medscape.com)
  • Had epididymis and spermatic cord on reverse side. (healthcaremagic.com)
  • I found my right epididymis at the reverse side of it's usual location and also the spermatic cord found at the reverse side of its usual location. (healthcaremagic.com)
  • The epididymis and the spermatic cord found in their usual location. (healthcaremagic.com)
  • Metastasis of the epididymis and spermatic cord from pancreatic adenocarcinoma: A rare entity. (pagepressjournals.org)
  • In literature, there are very low number of cases reporting metastasis from pancreatic cancer to epididymis and spermatic cord. (pagepressjournals.org)
  • Scrotal ultrasound revealed an inhomogeneous hypoechoic nodule of epididymis and/or spermatic cord. (pagepressjournals.org)
  • Conclusions: Malignancies of epididymis and spermatic cord are rare entities and, in literature, very low number of cases of metastasis from pancreatic carcinoma to epididymis and spermatic cord are described. (pagepressjournals.org)
  • while the posterior tubules are represented by the ductuli aberrantes, and by the paradidymis, which is sometimes found in front of the spermatic cord above the head of the epididymis. (wikipedia.org)
  • The histology and histochemistry of caput and corpus epididymis of each of 6 non-descript buffalo calves, six months old and adult buffalo was studied. (eurekamag.com)
  • I am a 23 years old male having problem in my right epididymis. (ndtv.com)
  • ICD-10-PCS code 0VUJ4JZ for Supplement Right Epididymis with Synthetic Substitute, Percutaneous Endoscopic Approach is a medical classification as listed by CMS under Male Reproductive System range. (aapc.com)
  • We have characterized the expression of α 1 -adrenoceptor in epididymis from rats in different stages of sexual maturation: 40 (immature), 60 (young adult), and 120 (adult) days of age. (bioone.org)
  • Reverse transcription polymerase chain reaction assay indicated that α 1a -, α 1b -, and α 1d -adrenoceptor transcripts were present in both caput and cauda epididymis from adult rats. (bioone.org)
  • Prazosin (nonselective α 1 antagonist), 5-methyl urapidil (α 1A -selective), and BMY 7378 (α 1D -selective) displaced [ 3 H]prazosin binding curves in caput and cauda epididymis from 40- and 120-day-old rats. (bioone.org)
  • Study on antagonistic effects of selenite on fluoride-induced impairments of testis and epididymis in rats]. (fluoridealert.org)
  • Methods: Five groups of SD male rats were provided with deionized drinking water containing 0 and 150 mg/L NaF, and containing both 150 mg/L NaF and 0.5, 2.0 or 4.0 mg/L Na2SeO3 respectively for 8 weeks, observing the levels of fluoride in blood and urine as well as the impairments of testis and epididymis of rats induced by 150 mg/L NaF. (fluoridealert.org)
  • Results: Fluoride could cause the elevation of fluorine concentrations in blood and urine, the abnormalities of trace elements in serum and testis, as well as the significant increase of lipid peroxide (LPO) levels, and the obvious decreases of activities of glutathione peroxidase (GSH-Px) and ATPase in testis and epididymis of rats exposed to fluoride in drinking water. (fluoridealert.org)
  • 2.0 mg/L Na2SeO3 in drinking water induced acceleration of fluoride excretion obviously in urine and possessed the certain adjustment of changes of trace elements in serum and testis, the most significant antagonistic effects of increases of LPO levels and decreases of GSH-Px and ATPase activities in testis and epididymis of rats exposed to fluoride, those of 0.5 and 4.0 mg/L Na2SeO3 were not powerful. (fluoridealert.org)
  • In this study, we demonstrated the constitutive immunoexpression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of Wistar rats treated with finasteride for 28 days (the duration of two cycles of the seminiferous epithelium) and 56 days (the duration of one spermatogenesis). (degruyter.com)
  • We noted that a 56-day finasteride treatment mainly caused a decrease in the level of circulating DHT, as well as a statistically insignificant decrease in the level of T. The hormone deficiency also led to a change in the iNOS immnoexpression in the testis and epididymis of the finasteride-treated rats. (degruyter.com)
  • This study aimed at comparing the morphology, assessed by histological analysis, and function of epididymis, by analysis of sperm parameters, antioxidant potential and Ca(2+) fluxes, between transgenic rats overexpressing RGN (Tg-RGN) and their wild-type littermates. (ualg.pt)
  • The majority of beta-defensin family members are exclusively expressed in the epididymis, and some members have been shown to play essential roles in sperm maturation and fertility in rats, mice and humans. (biomedcentral.com)
  • a small cyst adjacent to the head of the epididymis that is a remnant of the paramesonephric (müllerian) duct. (thefreedictionary.com)
  • The blockage of the ejaculatory duct or blockage of epididymis accounts for 1-5% of the male infertility causes. (fertilityproregistry.com)
  • However, when there is a blockage in the ejaculatory duct or epididymis, the sperm will not be ejaculated, though they are produced in the testes. (fertilityproregistry.com)
  • Treatment for the blockage of ejaculatory duct or the blockage of an epididymis is done through a small surgery. (fertilityproregistry.com)
  • STUDY HYPOTHESIS: Region-specific transcriptional profiling of tissues and cultured epithelial cells from the human epididymis will predict functional specialization along the duct. (luriechildrens.org)
  • An injury or infection of the epididymis causes epididymitis, a painful condition that can take months to heal . (wikipedia.org)
  • Is it an infection of the epididymis, or is it something else? (askthedoctor.com)
  • When I did see the doctor he claimed it was an infection of the epididymis. (askthedoctor.com)
  • In such cases, the sperm produced by the testes will not pass through the epididymis to ejaculate. (fertilityproregistry.com)
  • These data clearly demonstrate that testicular germ cells of the adult mouse and rat are able to synthesize active P450arom, and that there is a decrease in P450arom expression in sperm as they undergo maturation in the epididymis. (illinois.edu)
  • Epididymis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • In the embryo , the epididymis develops from tissue that once formed the mesonephros , a primitive kidney found in many aquatic vertebrates. (wikipedia.org)
  • The epididymis is an androgen-dependent tissue, and atrophy can be seen in response to decreased testosterone, decreased dihydrotestosterone (e.g., 5α-reductase inhibition), or androgen receptor antagonism. (nih.gov)
  • In the digital image above, a rat epididymis tissue section is presented that was labeled with the fluorophore Texas Red conjugated to wheat germ agglutinin, a fluorescent lectin that selectively binds to sialic acid residues. (microscopyu.com)
  • Torsion of the appendix testis and appendix epididymis occurs when tissue of the testis twists, which cuts off blood supply. (childrens.com)
  • Mouse CD1 epididymis cDNA is a full-length first strand cDNA synthesized from high quality CD1 Mouse epididymis tissue RNA by priming with oligo dT primers. (fishersci.com)
  • In order to localize a green fluorescent tag to filamentous actin in the sample of rat epididymis tissue presented in the digital image above, the specimen was labeled with Alexa Fluor 488 conjugated to phalloidin, a phallotoxin derived from the toxic death cap mushroom. (microscopyu.com)
  • Surgeries - Surgeries such as hernia or hydrocele repairs can scar a tissue in the epididymis causing a blockage. (fertilityproregistry.com)
  • STUDY DESIGN, SAMPLES/MATERIALS, METHODS: Using RNA sequencing on biological replicates, we described gene expression profiles for tissue from each region of the epididymis and cultured epithelial cells derived from these regions. (luriechildrens.org)
  • Given the large number of sperm present in the epididymis at any one time (several billion in the case of the bull, boar and ram), phagocytosis of even 0.1% would be readily detectable on tissue sections examined in the microscope, especially since sperm heads are difficult to digest intracellularly. (biologists.org)
  • A variety of target molecules expressed on epididymis tissue is used for the clinical diagnosis of epididymis disease, epididymis tissue is commonly used in immunohistochemical detection. (sinobiological.com)
  • Because sperm are initially non-motile as they leave the seminiferous tubules , large volumes of fluid are secreted to propel them to the epididymis. (wikipedia.org)
  • This absorption creates a fluid current that moves the immobile sperm from the seminiferous tubules to the epididymis. (wikipedia.org)
  • In our previous studies, we showed that a finasteride-induced DHT deficiency may cause changes in the morphology of the seminiferous epithelium without any morphological alteration of the epididymis. (degruyter.com)
  • The sperm that are produced in the seminiferous tubules flow into the epididymis. (wikipedia.org)
  • A weak-to-moderate reaction for AQP9 was observed in the nuclei of epithelial cells in the IS, caput and corpus of the epididymis. (ovid.com)
  • Consistent with these regional differences in epididymis function, we observed differential expression of transcription factors in the caput and corpus/cauda. (luriechildrens.org)
  • The aim of this work was to analyze the diagnostic and prognostic value of serum human epididymis protein 4 (HE4) and Risk for Ovarian Malignancy Algorithm (ROMA) in epithelial ovarian cancer (EOC). (aacrjournals.org)
  • Risk for Ovarian Malignancy Algorithm (ROMA) and Human epididymis protein 4 (HE4) appear to be promising predictors for epithelial ovarian cancer (EOC), however, conflicting results exist in the diagnostic performance comparison among ROMA, HE4 and CA125. (biomedcentral.com)
  • A 31-year-old man with recurrent testicular torsion and infertility was found to have a fusional anomaly of the epididymis on scrotal exploration in which only the head of epididymis was attached to the testis, while the body and tail were completely free. (ebscohost.com)
  • An image depicting the testes and epididymis can be seen below. (medscape.com)
  • The epididymis was observed to be highly convoluted at the cranial aspect of each testis as the catput epididymis, the medial aspects of the testis as the corpus epididymis and caudal aspects of the testes as the caudal epididymis. (pulsus.com)
  • The normal epididymis is iso-to-hyperechoic to the testes, with equal or less vascularity on colour and spectral Doppler. (radiopaedia.org)
  • The head of the epididymis is visualized superior and lateral to the testes, while the body and the tail are smaller with variable locations 2 . (radiopaedia.org)
  • epididymis has hyperintense signal, with slightly lower signal than testes. (radiopaedia.org)
  • The epididymis is a long, coiled tube that stores sperm and transports it from the testes. (sinobiological.com)
  • The epididymis (plural epididymides ) is situated adjacent to the testis within the scrotal sac . (radiopaedia.org)
  • The epididymis is the most common source of acute and chronic scrotal pain in the outpatient setting, yet there are no standardized methods for proper palpation of this organ. (canjurol.com)
  • Western blot, Northern blot, and reverse transcription-polymerase chain reaction analysis show that aldose reductase and sorbitol dehydrogenase are expressed at the transcriptional and translational levels along the human epididymis. (nih.gov)
  • The epididymis is the part of the human male reproductive system . (wikipedia.org)
  • In all, this circumstantial evidence makes it seem possible that the human epididymis as well as the testis often exists in a state of temperature-induced partial suppression. (nih.gov)
  • Transmission electron micrograph (TEM) of epithelium of the human epididymis, cut at the level of the nuclei. (sciencephoto.com)
  • Human epididymis protein 4 (HE4) is such a marker that has recently been reported to correlate with recurrence or progression of epithelial ovarian cancer. (scirp.org)
  • Detection of the human epididymis secretory protein 4 (HE4) biomarker plays an important role in the early diagnosis of ovarian cancer. (dovepress.com)
  • Thimon V, Koukoui O, Calvo E, Sullivan R. Region-specific gene expression profiling along the human epididymis. (springer.com)
  • We showed in the immunohistochemistry study the expression of FSH-R in rat and human ductuli efferentes and the caput, corpus, and cauda epididymis, moreover, by Western blot analysis in the caput and cauda epididymis of rat. (hindawi.com)
  • In conclusion, the identification of FSH receptors in human and rat epididymides supports our results that the epididymis is a target organ not only for LH but additionally for FSH. (hindawi.com)
  • Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human epididymis protein 4 ( HE4 ). (aacrjournals.org)
  • WIDER IMPLICATIONS OF THE FINDINGS: Our data provide a molecular characterization that will facilitate advances in understanding human epididymis epithelium biology in health and disease. (luriechildrens.org)
  • Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer', Asian Pacific Journal of Cancer Prevention , 17(9), pp. 4483-4486. (waocp.org)
  • Innao, P., Pothisuwan, M., Pengsa, P. Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer. (waocp.org)
  • Human epididymis protein 4 (HE4) is a novo diagnostic tumor marker for EOC. (waocp.org)
  • Immunochemical staining of human DDX4 in human epididymis with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). (sinobiological.com)
  • The potency order for these antagonists, as calculated from the negative logarithm of the inhibition constant (pK i ) values for the high-affinity sites, indicated a predominant population of α 1A -adrenoceptor subtype in caput and cauda epididymis from adult animals. (bioone.org)
  • Differences in pK i values in caput and cauda epididymis from immature and adult animals also suggested that the relative amount of α 1 -adrenoceptors, at the protein level, is modulated by sexual maturation. (bioone.org)
  • Treatment of adult male mice with sodium fluoride (NaF, 10 mg/kg bw/day) and aluminium chloride (AlCl3, 200 mg/kg bw/day) simultaneously for 30 days caused marked histological changes in the epididymis accompanied by decreased levels of protein and sialic acid and also lowered activities of adenosine triphosphatase (ATPase) and succinate dehydrogenase (SDH) in caput and cauda epididymides with evident alteration of sperm maturation in mice. (fluoridealert.org)
  • The alveoli and ducts were lined with tall columnar epithelium in the caput epididymis of calves and it was pseudostratified columnar with branched stereocilia in corpus epididymis of calves and adult animals. (eurekamag.com)
  • Sperm entering the caput epididymis are incomplete-they lack the ability to swim forward (motility) and to fertilize an egg. (wikipedia.org)
  • During their transit in the epididymis, sperm undergo maturation processes necessary for them to acquire motility and fertility. (wikipedia.org)
  • The epididymis secretes an intraluminal environment that suppresses sperm motility until ejaculation. (wikipedia.org)
  • Tg-RGN animals displayed an altered morphology of epididymis and lower sperm counts and motility. (ualg.pt)
  • Sperm mature here in the epididymis until they gain motility and other mystical reproductive powers. (biologyprints.com)
  • The expression of FSH receptor (FSH-R) was detected also in epithelial cells of the caput epididymis of rat and monkey. (hindawi.com)
  • In vitro, DHT did not modify NO production by the epithelial cells of the caput epididymis even when stimulated with LPS and IFNγ, but it did give rise to an increase in NO production by the epithelial cells of the cauda epididymis without the stimulation. (degruyter.com)
  • DHT did not have a statistically significant influence on estradiol production by cultured, LPS- and IFNγ-stimulated epithelial cells from the caput and cauda epididymis. (degruyter.com)
  • AQP1 immunoreactivity was observed in the apex of the ED, and AQP9 was found adjacent to the nuclei of the epithelial cells of the ED. The epithelial lining of ram epididymis is pseudostratified columnar and presents principal, basal, apical and narrow cells. (ovid.com)
  • Sperm made in the testis go into the head ( caput ) of the epididymis, go through the body ( corpus ) and stop at the tail ( cauda ), where they are stored. (wikipedia.org)
  • When the sperm are ejaculated, they move through the tail of the epididymis. (wikipedia.org)
  • Decreased diameter of empty ducts in the body and tail of the epididymis in a male F344/N rat from a subchronic study. (nih.gov)
  • The tail of the epididymis is found at the inferior pole of the testis 3 . (radiopaedia.org)
  • Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). (umassmed.edu)
  • STD infections block the tail of the epididymis or cause inflammation in other parts of the genital tract, thus preventing the sperm to ejaculate. (fertilityproregistry.com)
  • and if the cause of death is not related to a chronic and debilitating disease, it is very likely that all the semen produced and stored in the tail of the epididymis is recoverable and processable. (sa-boergoats.com)
  • The caudal part (tail) of the epididymis is the major site of sperm storage. (sa-boergoats.com)
  • The epididymis can be divided into three main regions: the head, the body and the tail. (sinobiological.com)
  • We systematically identified 32 novel genes with epididymis-specific or -predominant expression in the mouse epididymis UniGene library, containing 1505 gene-oriented transcript clusters, by in silico and in vitro analyses. (biomedcentral.com)
  • However, the role of autophagy in spermiophagy during sperm storage in turtle epididymis still needs to be studied. (aging-us.com)
  • In this study, we reported in vivo spermiophagy via the cellular evidence of lysosome engulfment and autophagy within the principal cells during sperm storage in the turtle epididymis. (aging-us.com)
  • In conclusion, spermiophagy occurs by lysosomal engulfment and autophagic activity within the principal cells of the turtle epididymis during sperm storage. (aging-us.com)
  • In the present study, specific antipeptide antibodies against the second extracellular loops of angiotensin II type I (AT1) and type II (AT2) receptors were used to localize immunocytochemically these receptors in the rat cauda epididymides of three developmental stages, namely, immature (2-week), early mature (6-week) and fully mature (10-week). (deepdyve.com)
  • Following freeze-fracture of the rat epididymis, a population of cells whose apical, but not baso-lateral, plasma membrane contains elongated intramembrane particles was found in the initial segment. (biologists.org)
  • On the basis of these observations, we suggest that the apical cells may play a role in fluid and/or electrolyte transport in the initial segment of the epididymis. (biologists.org)
  • While the immunostaining for both AT1 and AT2 receptors in the younger rat epididymides appeared to be distributed in both basal and apical regions, the immunostaining in the fully mature epididymis was predominantly localized in the basal region. (deepdyve.com)
  • Apocrine secretion did not appear to occur in the epididymis of these birds as the apical blebs of Types I, II and III cells, which have previously been reported, only manifest in this study in inadequately fixed tissues, and were therefore viewed as being artefacts. (up.ac.za)
  • During passage via the epididymis, the sperm undergo maturation and are concentrated by the action of ion channels located on the apical membrane of the epididymis. (wikipedia.org)
  • It was concluded that androgens maintain the basic activity of Na$\sp+$,K$\sp+$-ATPase in the ductuli efferentes and the head of the epididymis and this action is possibly mediated by androgen receptors. (illinois.edu)
  • We showed that both ligands and receptors were produced by immune and non-immune cells in the epididymis, whatever the age mice have. (inserm.fr)
  • Angiotensin II receptors: Localization of type I and type II in rat epididymides of different. (deepdyve.com)
  • The immunostaining intensity for AT1 receptors was found to be stronger than that for AT2 receptors throughout rat epididymides of all stages. (deepdyve.com)
  • However, the immunostaining for both AT2, and AT2 receptors observed in the fully mature rat epididymis was much more intense than that observed in the epididymides of the two younger stages. (deepdyve.com)
  • P2X(5-7) receptors were examined but found to be absent.Conclusion(s): The change in localization of receptor subtypes is coincidental with the functionally essential morphologic and maturational changes seen in sperm as they travel through the epididymis, and is suggestive of a role for purinergic signaling in sperm maturation and possibly fertility. (ucl.ac.uk)
  • I know the drill and what to look for, and I check myself regularly for testicular cancer (although I'm not completely certain how to check for lumps in the epididymis as it is lumpy to begin with). (netdoctor.co.uk)
  • Reduced sperm content is generally caused by reduced testicular spermatogenesis but can also be due to an obstructive lesion in the efferent ducts preventing sperm from a normal-appearing testis from reaching the epididymis. (nih.gov)
  • Atrophy of the epididymis is generally associated with decreased luminal sperm content, secondary to decreased testicular spermatogenesis. (nih.gov)
  • The deferential artery (a branch of superior vesical artery ) and the testicular artery (a branch off the aorta ) supply the inferior and superior portions of the epididymis, respectively. (radiopaedia.org)
  • Some sources state that the epididymis is supplied only by branches of the testicular artery 5 . (radiopaedia.org)
  • In this study we analyzed cadmium transport into tissues with a vascular barrier, the testis, epididymis, and brain, in an attempt to characterize the mechanisms of strain resistance to cadmium-induced testicular toxicity. (aspetjournals.org)
  • Therefore, post-testicular maturation of sperm is not under the control of the germinal genome but rather it is mediated by factors within the lumen of the epididymis. (biomedcentral.com)
  • Opec.go.th Most Effective boosted board alternative Shop, can you get testicular epididymis from male enhancement pills. (opec.go.th)
  • The appointment was made and they were not married can you get testicular epididymis from male enhancement pills Best Man Enhancement Pill yet. (opec.go.th)
  • Now my Genuine can you get testicular epididymis from male enhancement pills wife is getting angry, even if I am not, I will ask can you get testicular epididymis from male enhancement pills Is Your Best Choice to move out in three or two days, and I dare to persuade me. (opec.go.th)
  • can you get testicular epididymis from male enhancement pills Best Sex Pills Daiyu ordered Zijuan to boosted board alternative Low Price bring her clothes and go massage for penis enlargement with trt and male enhancement her. (opec.go.th)
  • Until the end of the Warring States period, Lingnan, known can you get testicular epididymis from male enhancement pills Sexual Enhancers as the Hundred Yue land, had many castes, each with a monarch, and not under each other. (opec.go.th)
  • Zhang Liang did not seem to have the ambition to can you get testicular epididymis from male enhancement pills Best Sex Enhancer help Liu destroy Xiang to prosper extra long male sperical rod end supplements for testosterone increase and perish Chu. (opec.go.th)
  • Zhang Er how long should an erection last Genuine can you get testicular epididymis from male enhancement pills is Zhao Xiang, who boosted board alternative Low Price is known as a virtuous person and has made numerous do extenze pills make you bigger contributions, and then followed Xiang Yu into Hangu Pass. (opec.go.th)
  • If your house father in law, son in law seeks you, can you get testicular epididymis from male enhancement pills Best Sex Enhancer twice dodge it, naturally Involved in a lawsuit. (opec.go.th)
  • If you want to donate it, Chu can you get testicular epididymis from male enhancement pills Is Your Best Choice why do i have erectile dysfunction can break it. (opec.go.th)
  • When returning to the army to boosted board alternative Best Sex Enhancer attack Hu Yang, they met Mei can you get testicular epididymis from male enhancement pills Extenze Male Enhancement Yun, the general of Pojun can you get testicular epididymis from male enhancement pills Is Your Best Choice Wu Rui, and together they captured the two cities of Analysis and Li. (opec.go.th)
  • Testicular atrophy associated with agenesis of the epididymis in the ACI rat. (semanticscholar.org)
  • In reptiles, there is an additional canal between the testis and the head of the epididymis and which receives the various efferent ducts. (wikipedia.org)
  • These tubules empty their contents into a network of anastomosing ducts, which ultimately empties into the epididymis. (medscape.com)
  • The ducts of the cauda epididymis seemed to be larger than those of both the catput and corpus epididymis. (pulsus.com)
  • Conelike divisions of the head of the epididymis formed by the much-coiled distal ends of the efferent ducts of the testis. (thefreedictionary.com)
  • Impaired delivery of sperm is due to cystic fibrosis, presence of anti-sperm antibodies, hypospadias, blockage of ejaculatory ducts or blockage of epididymis, retrograde ejaculation and other sexual issues. (fertilityproregistry.com)
  • This study was designed to understand the morphology and localization of AQPs in ram efferent ducts (ED) and epididymis. (ovid.com)
  • The various ducts of the epididymides of four gallinaceous birds, the turkey (Meleagris gallopavo) , domestic fowl (Gallus gallus), guinea-fowl (Numida meleagris) and Japanese quail (Coturnix coturnix japonica) were studied at the scanning and transmission electron microscopy levels. (up.ac.za)
  • Fluid movement in the epididymis is important for modulation of the luminal environment, in which sperm mature and reside. (ovid.com)
  • In particular, it controls the luminal environment in the epididymis, which is required for normal sperm maturation and reproductive competence. (luriechildrens.org)
  • They may also reveal the mechanisms coordinating epididymis luminal environment and sperm maturation. (luriechildrens.org)
  • The epididymis has been regarded as a highly specialized ductal system that forms an integral part of the male reproductive system. (pulsus.com)
  • An inflammation of the epididymis is called epididymitis. (wikipedia.org)
  • The absence of IDO generated an inflammatory state in the caput epididymis as revealed by an increased accumulation of various inflammation markers. (uni-regensburg.de)
  • If bacteria gets into the epididymis it can lead to inflammation. (guttogjente.no)
  • Resistant murine strains demonstrate a decreased cadmium concentration in the testis and also in the epididymis and seminal vesicle. (aspetjournals.org)
  • and also in the epididymis and seminal vesicle (King et al. (aspetjournals.org)
  • A reduced number of sperm in the epididymis in a male B6C3F1 mouse from a subchronic study. (nih.gov)
  • These data exclude direct genomic effects of gestagens at the spermatogenic level but indicate that a male contraceptive based on gestagens might have some effects on other tissues, such as the epididymis, prostate and mammary gland. (labome.org)
  • What the the epididymis feel like andvis it in every male? (healthtap.com)
  • HE4 is expressed in the male epididymis. (aacrjournals.org)
  • We report a case of aggressive angiomyxoma arising from the epididymis of a young male, which was treated by radical orchiectomy. (canjurol.com)
  • Background: The interface between the epididymis and the immune system is implicated in many male reproductive pathologies. (monash.edu)
  • The anatomic divisions of the epididymis include the initial segment, the head also referred as the caput, the middle segment, the corpus and the distal segment, the caudal epididymis. (pulsus.com)
  • The epithelium was pseudostratified, and changed to tall columnar and low columnar with cilia in the catput, corpus and cauda epididymis respectively. (pulsus.com)