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EpendymomaInfratentorial NeoplasmsSpinal Cord NeoplasmsSupratentorial NeoplasmsBrain NeoplasmsCerebral Ventricle NeoplasmsCentral Nervous System NeoplasmsCauda EquinaSiderosisSacrococcygeal RegionNeurosurgical ProceduresRadiotherapy, ConformalMedulloblastomaFourth VentricleGlioma, SubependymalEpendymaAraliaceaeGliomaHealth Records, PersonalCellular PhoneMobile ApplicationsHospitals, UniversityPatient Access to RecordsElectronic Health RecordsEncyclopedias as TopicNeurofibromatosis 1Neurofibromatosis 2AsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonCombined Modality TherapySpinal Cord DiseasesLow Back PainSpinal NeoplasmsKarnofsky Performance StatusCreatinineTreatment OutcomeBone MarrowCarboplatinBaltimoreMarylandResearchPathology Department, HospitalSpinal Cord CompressionRetrospective StudiesSpineRadiologyInternetUser-Computer InterfaceSoftwareWeb BrowserComputer Graphics
Ependymoma: Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)Infratentorial Neoplasms: Intracranial tumors originating in the region of the brain inferior to the tentorium cerebelli, which contains the cerebellum, fourth ventricle, cerebellopontine angle, brain stem, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS).Spinal Cord Neoplasms: Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.Supratentorial Neoplasms: Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.Cerebral Ventricle Neoplasms: Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.Cauda Equina: The lower part of the SPINAL CORD consisting of the lumbar, sacral, and coccygeal nerve roots.Siderosis: A form of pneumoconiosis resulting from inhalation of iron in the mining dust or welding fumes.Sacrococcygeal Region: The body region between (and flanking) the SACRUM and COCCYX.Neurosurgical Procedures: Surgery performed on the nervous system or its parts.Radiotherapy, Conformal: Radiotherapy where there is improved dose homogeneity within the tumor and reduced dosage to uninvolved structures. The precise shaping of dose distribution is achieved via the use of computer-controlled multileaf collimators.Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)Fourth Ventricle: An irregularly shaped cavity in the RHOMBENCEPHALON, located between the MEDULLA OBLONGATA; the PONS; and the isthmus in front, and the CEREBELLUM behind. It is continuous with the central canal of the cord below and with the CEREBRAL AQUEDUCT above, and through its lateral and median apertures it communicates with the SUBARACHNOID SPACE.Glioma, Subependymal: Rare, slow-growing, benign intraventricular tumors, often asymptomatic and discovered incidentally. The tumors are classified histologically as ependymomas and demonstrate a proliferation of subependymal fibrillary astrocytes among the ependymal tumor cells. (From Clin Neurol Neurosurg 1997 Feb;99(1):17-22)Ependyma: A thin membrane that lines the CEREBRAL VENTRICLES and the central canal of the SPINAL CORD.Araliaceae: The ginseng plant family of the order Apiales, subclass Rosidae, class Magnoliopsida. Leaves are generally alternate, large, and compound. Flowers are five-parted and arranged in compound flat-topped umbels. The fruit is a berry or (rarely) a drupe (a one-seeded fruit). It is well known for plant preparations used as adaptogens (immune support and anti-fatigue).Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)Health Records, Personal: Longitudinal patient-maintained records of individual health history and tools that allow individual control of access.Cellular Phone: Analog or digital communications device in which the user has a wireless connection from a telephone to a nearby transmitter. It is termed cellular because the service area is divided into multiple "cells." As the user moves from one cell area to another, the call is transferred to the local transmitter.Mobile Applications: Computer programs or software installed on mobile electronic devices which support a wide range of functions and uses which include television, telephone, video, music, word processing, and Internet service.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Patient Access to Records: The freedom of patients to review their own medical, genetic, or other health-related records.Electronic Health Records: Media that facilitate transportability of pertinent information concerning patient's illness across varied providers and geographic locations. Some versions include direct linkages to online consumer health information that is relevant to the health conditions and treatments related to a specific patient.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).Neurofibromatosis 2: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.Asparaginase: A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.BostonCombined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.Low Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.Spinal NeoplasmsKarnofsky Performance Status: A performance measure for rating the ability of a person to perform usual activities, evaluating a patient's progress after a therapeutic procedure, and determining a patient's suitability for therapy. It is used most commonly in the prognosis of cancer therapy, usually after chemotherapy and customarily administered before and after therapy. It was named for Dr. David A. Karnofsky, an American specialist in cancer chemotherapy.CreatinineTreatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Bone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.Carboplatin: An organoplatinum compound that possesses antineoplastic activity.BaltimoreMarylandResearch: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Pathology Department, Hospital: Hospital department which administers and provides pathology services.Spinal Cord Compression: Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Spine: The spinal or vertebral column.Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Web Browser: Software application for retrieving, presenting and traversing information resources on the World Wide Web.Computer Graphics: The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.

Extraneural metastasizing ependymoma of the spinal cord. (1/337)

This paper reports a case of the rare entity of an extraneural metastasizing ependymoma of the spinal cord. The tumor which arose in the conus medullaris and in the cauda equina was first diagnosed in 1956 when a thoracolumbar myeloresection was performed. At autopsy, 40 years after the primary diagnosis, a massive local tumor recurrence with extraneural metastases in the lungs, the pleura, the liver, and the thoracal and abdominal lymph nodes were found. Immunohistochemical stains of the extraneural metastases showed a strong cytoplasmatic expression of glial fibrillary acidic protein (GFAP). Neither the primary tumor nor its metastases showed any of the conventional morphological criteria of malignancy. Reviewing the literature we discuss the possible mechanism of extraneural tumor spread and the incidence of metastases with regard to the tumor type.  (+info)

Familial gliomas : a case report. (2/337)

Two non-twin brothers were found to have intracranial malignant neoplasms. The age of presentation was third and fourth decade but the onset was simultaneous, at the same time. Diagnosis in each of them was made by computed tomography and confirmed by histopathology. Elder among them had cellular ependymoma and the younger had oligodendroglioma. Both the brothers received radiotherapy post operatively and were surviving asymptomatically without any neurological deficit, leading active life as police constable, 12 months after surgical treatment.  (+info)

Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. (3/337)

Ependymal tumors are heterogeneous with regard to morphology, localization, age at first clinical manifestation, and prognosis. Several molecular alterations have been reported in these tumors, including allelic losses on chromosomes 10, 17, and 22 and mutations in the NF2 gene. However, in contrast to astrocytic gliomas, no consistent molecular alterations have been associated with distinct types of ependymal tumors. To evaluate whether morphological subsets of ependymomas are characterized by specific genetic lesions, we analyzed a series of 62 ependymal tumors, including myxopapillary ependymomas, subependymomas, ependymomas, and anaplastic ependymomas, for allelic losses on chromosome arms 10q and 22q and mutations in the PTEN and NF2 genes. Allelic losses on 10q and 22q were detected in 5 of 56 and 12 of 54 tumors, respectively. Six ependymomas carried somatic NF2 mutations, whereas no mutations were detected in the PTEN gene. All six of the NF2 mutations occurred in ependymomas of WHO grade II and were exclusively observed in tumors with a spinal localization (P = 0.0063). These findings suggest that a considerable fraction of spinal ependymomas are associated with molecular events involving chromosome 22 and that mutations in the NF2 gene may be of primary importance for their genesis. Furthermore, our data suggest that the more favorable clinical course of spinal ependymomas may relate to a distinct pattern of genetic alterations different from that of intracerebral ependymomas.  (+info)

Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2. (4/337)

A 15 year old male, who had earlier been operated for intraspinal intramedullary ependymoma, subsequently developed a right cerebello pontine (CP) angle mass. A diagnosis of right CP angle ependymoma was considered, in view of established histology of previously operated spinal lesion. Histopathological examination of the well defined extra-axial mass, which was attached with ninth cranial nerve, however revealed a schwannoma. A diagnosis of Neurofibromatosis-2 (NF2) is strongly suspected, because of well established fact, that the spinal ependymomas may have association with lower cranial nerve schwannomas in NF2. Cranial and spinal MRI screening for early diagnosis of associated, asymptomatic lesions, in suspected cases of NF2, particularly in children, is recommended.  (+info)

Tumour type and size are high risk factors for the syndrome of "cerebellar" mutism and subsequent dysarthria. (5/337)

OBJECTIVE: "Cerebellar mutis" and subsequent dysarthria (MSD) is a documented complication of posterior fossa surgery in children. In this prospective study the following risk factors for MSD were assessed: type, size and site of the tumour; hydrocephalus at presentation and after surgery, cerebellar incision site, postoperative infection, and cerebellar swelling. METHODS: In a consecutive series of 42 children with a cerebellar tumour, speech and neuroradiological studies (CT and MRI) were systematically analysed preoperatively and postoperatively. Speech was assessed using the Mayo Clinic lists and the severity of dysarthria using the Michigan rating scale. RESULTS: Twelve children (29%) developed MSD postoperatively. The type of tumour, midline localisation, and vermal incision were significant single independent risk factors. In addition, an interdependency of possible risk factors (tumour>5 cm, medulloblastoma) was found. CONCLUSION: MSD often occurs after paediatric cerebellar tumour removal and is most likely after removal of a medulloblastoma with a maximum lesion diameter>5 cm.  (+info)

Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2. (6/337)

Ependymomas are glial tumours of the brain and spinal cord. The most frequent genetic change in sporadic ependymoma is monosomy 22, suggesting the presence of an ependymoma tumour suppressor gene on that chromosome. Clustering of ependymomas has been reported to occur in some families. From an earlier study in a family in which four cousins developed an ependymoma, we concluded that an ependymoma-susceptibility gene, which is not the NF2 gene in 22q12, might be located on chromosome 22. To localize that gene, we performed a segregation analysis with chromosome 22 markers in this family. This analysis revealed that the susceptibility gene may be located proximal to marker D22S941 in 22pter-22q11.2. Comparative genomic hybridization showed that monosomy 22 was the sole detectable genetic aberration in the tumour of one of the patients. Loss of heterozygosity studies in that tumour revealed that, in accordance to Knudson's two-hit theory of tumorigenesis, the lost chromosome 22 originated from the parent presumed to have contributed the wild-type allele of the susceptibility gene. Thus, our segregation and tumour studies collectively indicate that an ependymoma tumour suppressor gene may be present in region 22pter-22q11.2.  (+info)

Expression of bisecting GlcNAc in pediatric brain tumors and its association with tumor cell response to vinblastine. (7/337)

Increased expression of the bisecting GlcNAc has been correlated with tumor progression in several experimental tumor models. Its expression and function in brain tumors are, however, not yet known. In this study, we investigated expression of the bisecting GlcNAc structure in a series of pediatric brain tumors and its relationship to tumor response to vinblastine. A plant lectin (E-PHA) that recognizes the bisecting GlcNAc structure was used for detection of this molecule in a total of 90 pediatric brain tumors and normal brain tissue specimens. Our results showed that, whereas E-PHA staining was undetectable in the normal brain tissue, pediatric brain tumor specimens exhibited different levels of reactivity. Lectin staining was particularly prominent in high-grade astrocytomas (73%) and ependymomas (72%). In astrocytomas, there was a positive correlation with the tumor grade, which suggests that the bisecting GlcNAc may be of particular interest as a tumor marker for diagnosis and/or prognosis. By using a human glioma cell culture model, we have found that treatment of these cells with E-PHA lectin enhances their sensitivity to vinblastine. E-PHA interacted directly with the drug transporter P-glycoprotein and inhibited its drug efflux function. In a drug-resistant glioma cell line transfected with the mdr1 gene, drug resistance was reversed by E-PHA. Our findings indicate that: (a) expression of the bisecting GlcNAc in pediatric brain tumors may have a potential relevance as a tumor marker; and (b) glioma response to chemotherapy may be modulated through the bisecting GlcNAc.  (+info)

Neuropsychological consequences of cerebellar tumour resection in children: cerebellar cognitive affective syndrome in a paediatric population. (8/337)

Acquired cerebellar lesions in adults have been shown to produce impairments in higher function as exemplified by the cerebellar cognitive affective syndrome. It is not yet known whether similar findings occur in children with acquired cerebellar lesions, and whether developmental factors influence their presentation. In studies to date, survivors of childhood cerebellar tumours who demonstrate long-term deficits in cognitive functions have undergone surgery as well as cranial irradiation or methotrexate treatment. Investigation of the effects of the cerebellar lesion independent of the known deleterious effects of these agents is important for understanding the role of the cerebellum in cognitive and affective development and for informing treatment and rehabilitation strategies. If the cerebellar contribution to cognition and affect is significant, then damage in childhood may influence a wide range of psychological processes, both as an immediate consequence and as these processes fail to develop normally later on. In this study we evaluated neuropsychological data in 19 children who underwent resection of cerebellar tumours but who received neither cranial irradiation nor methotrexate chemotherapy. Impairments were noted in executive function, including planning and sequencing, and in visual-spatial function, expressive language, verbal memory and modulation of affect. These deficits were common and in some cases could be dissociated from motor deficits. Lesions of the vermis in particular were associated with dysregulation of affect. Behavioural deficits were more apparent in older than younger children. These results reveal that clinically relevant neuropsychological changes may occur following cerebellar tumour resection in children. Age at the time of surgery and the site of the cerebellar lesion influence the neurobehavioural outcome. The results of the present study indicate that the cerebellar cognitive affective syndrome is evident in children as well as in adults, and they provide further clinical evidence that the cerebellum is an essential node in the distributed neural circuitry subserving higher-order behaviours.  (+info)

Pediatric ependymoma - WikipediaPediatric ependymoma - Wikipedia
Pediatric ependymomas are similar in nature to the adult form of ependymoma in that they are thought to arise from radial glial cells lining the ventricular system. However, they differ from adult ependymomas in which genes and chromosomes are most often affected, the region of the brain they are most frequently found in, and the prognosis of the patients. Children with certain hereditary diseases, such as neurofibromatosis type II (NF2), have been found to be more frequently afflicted with this class of tumors, but a firm genetic link remains to be established. Symptoms associated with the development of pediatric ependymomas are varied, much like symptoms for a number of other pediatric brain tumors including vomiting, headache, irritability, lethargy, and changes in gait. Although younger children and children with invasive tumor types generally experience less favorable outcomes, total removal of the tumors is the most conspicuous prognostic factor for both survival and relapse. Ependymomas ...
Ependymal tumor - WikipediaEpendymal tumor - Wikipedia
An ependymal tumor is a type of brain tumor that begins in cells lining the spinal cord central canal (fluid-filled space down the center) or the ventricles (fluid-filled spaces of the brain). Ependymal tumors may also form in the choroid plexus (tissue in the ventricles that makes cerebrospinal fluid). Also called ependymoma. Ependymal tumor entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms ...
Spinal myxopapillary ependymoma | Radiology Reference Article | Radiopaedia.orgSpinal myxopapillary ependymoma | Radiology Reference Article | Radiopaedia.org
Spinal myxopapillary ependymomas are a variant type of spinal ependymoma that occur almost exclusively in the conus medullaris and filum terminale. They represent 13% of all spinal ependymomas, and are by far the most common tumours of the conus ...
Tanycytic Ependymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsTanycytic Ependymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
MalaCards based summary : Tanycytic Ependymoma is related to ependymoma and benign ependymoma. An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include spinal cord and brain, and related phenotypes are Increased proliferation and growth/size/body region ...
ASTRO 2015: Pediatric Patients With Ependymoma Have Favorable Outcomes With Immediate Postsurgical Radiation Therapy - The ASCO...ASTRO 2015: Pediatric Patients With Ependymoma Have Favorable Outcomes With Immediate Postsurgical Radiation Therapy - The ASCO...
Outcomes for pediatric patients as young as 12 months old with ependymoma who are treated with immediate postoperative radiation therapy are favorable and consistent, based upon tumor surgical resection and tumor grade, according to research presented by Merchant et al (Abstract 1) on October 18, 2015, at the American Society for Radiation Oncology (ASTRO) 57th Annual Meeting. The Childrens Oncology Group ACNS0121 trial was a prospective study for childhood ependymoma-a rare brain and spinal cord tumor. This was the largest prospective trial for childhood ependymoma ever conducted and the first cooperative group trial for ependymoma to target the postoperative tumor bed and to use three-dimensional conformal radiation therapy and intensity-modulated radiation therapy.. In addition, this study is significant in that it was the first to systematically use immediate postoperative radiation therapy in children under the age of 3 with this type of brain tumor. Many children diagnosed with ependymoma ...
Ependymal tumor | Open Access articles | Open Access journals | Conference Proceedings | Editors | Authors | Reviewers |...Ependymal tumor | Open Access articles | Open Access journals | Conference Proceedings | Editors | Authors | Reviewers |...
An ependymal tumor is a type of brain tumor that begins in cells lining the spinal cord central canal (fluid-filled space down the center) or the ventricles (fluid-filled spaces of the brain). Ependymal tumors may also form in the choroid plexus (tissue in the ventricles that makes cerebrospinal fluid). Also called ependymoma. ...
Ependymoma - Dana-Farber Cancer Institute | Boston, MAEpendymoma - Dana-Farber Cancer Institute | Boston, MA
Ependymoma (ependymal tumor) may arise in the ventricles of the brain or in the spinal cord. Learn about ependymoma and find information on how we support and care for children and teens with ependymoma before, during, and after treatment.
Final Diagnosis -- Case 95Final Diagnosis -- Case 95
DISCUSSION. Ependymomas are the third most common brain tumor in the pediatric population. Over 90% of these cases are intracranial, while in adults, most ependymomas occur in the spinal cord. In children, most intracranial ependymomas are infratentorial, where their relationship to the floor of the fourth ventricle often makes complete resection difficult. Supratentorial ependymomas may occur in relation to the lateral ventricles or in the midline, as in this case. It has been noted that supratentorial midline ependymomas are more likely to exhibit clear-cell morphology (20) , which may so dominate the histologic picture as to warrant a diagnosis of clear-cell variant of ependymoma. In the case presented here, only focal areas showed clear-cell histology, while most areas showed the more classic architecture of a cellular ependymoma. This case also had numerous areas of necrosis, significant endothelial proliferation and an extrememly high mitotic rate: sometimes as many as 5 mitotic figures ...
Giant cell ependymoma of the thoracic spinal cord | springermedizin.deGiant cell ependymoma of the thoracic spinal cord | springermedizin.de
We report a new case of giant cell ependymoma (GCE) of the thoracic spinal cord. Ependymomas predominate in children and young adults and are
Myxopapillary ependymoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS ProgramMyxopapillary ependymoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Myxopapillary ependymoma
Treatment of Children With Recurrent Refractory Brain/Solid Tumors and Recurrent Ependymoma - Full Text View - ClinicalTrials...Treatment of Children With Recurrent Refractory Brain/Solid Tumors and Recurrent Ependymoma - Full Text View - ClinicalTrials...
Aberrant DNA methylation is frequently observed in many pediatric solid tumors, but in particularly several entities such as ependymoma, medulloblastoma, embryonal tumor with multilayered rosettes, atypical/teratoid rhabdoid tumor, neuroblastoma and wilms tumor have promoter hypermethylation. Treatment with DNMTi (DNA methyltransferase inhibitors) agents such as 5-azacytidine has been shown to be safe and efficacious in adult myelodysplastic syndromes, causing significant decreased DNA methylation in blood, with maximum effect at day 15 of each cycle. However, monotherapy with DNMTi has been shown to result in resistance in leukamias and efficacy in solid tumours is limited. Synergy between DNMTi and platinum agents has shown promise in pre-clinical models including pediatric ependymoma, and in addition, the combination of demethylating agents with carboplatin has provided promising results in platinum resistant ovarian cancers. However, this approach has not been applied to pediatric solid ...
Metastatic ependymoma of the sacrum<...Metastatic ependymoma of the sacrum<...
TY - JOUR. T1 - Metastatic ependymoma of the sacrum. AU - Miralbell, Raymond. AU - Louis, David N.. AU - OKeeffe, David. AU - Rosenberg, Andrew E.. AU - Suit, Herman D.. PY - 1990/5/15. Y1 - 1990/5/15. N2 - Ependymomas originating in the sacrum or extraspinal parasacral soft tissues are rare tumors. The majority are of the myxopapillary type and may be locally destructive. Even though metastases are not uncommon in retrosacral ependymomas, they have been rarely described in intrasacral locations. A case is reported of a large intrasacral ependymoma with metastases to several vertebrae. Radiologic and pathologic studies are presented. Treatment options are discussed.. AB - Ependymomas originating in the sacrum or extraspinal parasacral soft tissues are rare tumors. The majority are of the myxopapillary type and may be locally destructive. Even though metastases are not uncommon in retrosacral ependymomas, they have been rarely described in intrasacral locations. A case is reported of a large ...
Late dissemination of ependymoma: case reportLate dissemination of ependymoma: case report
BADEMCI, G. et al. Late dissemination of ependymoma: case report. Neurocirugía [online]. 2007, vol.18, n.4, pp.333-336. ISSN 1130-1473.. Spinal cord dissemination over 10 years after surgical removal of the fourth ventricle ependymoma without local recurrence is extremely rare. A 49-year-old male underwent a macroscopically gross total emoval of the fourth ventricle ependymoma and postoperative radiothe rapy to the posterior fossa. Twelve years after the initial operation, the patient complained from uncontrolled fever attacks, low back pain and numbness of the legs. Spinal Magnetic Resonance Imaging revealed intradural extramedullary mass lesions located at the thoracic 2-3 and lumbar 5 vertebrae levels. Cerebrospinal fluid exami nation showed no tumour cells. He underwent total excision of these spinal lesions. Although the majority of the recurrences take place within a few years after surgery, we experienced a case with multiple spinal disseminations 12 years after the resection of the ...
A retrospective analysis of recurrent intracranial ependymoma - Antony - 2014 - Pediatric Blood & Cancer - Wiley Online LibraryA retrospective analysis of recurrent intracranial ependymoma - Antony - 2014 - Pediatric Blood & Cancer - Wiley Online Library
Median duration of follow-up was 52 months (7-171 months). Median age at initial diagnosis was 4 years (0.3-19 years) with 8 patients younger than 3 years at presentation. Eleven patients had anaplastic and 11 cellular pathologies. Eighteen patients had infratentorial tumors at diagnosis and 3 (all infratentorial) had metastatic spinal cord involvement at presentation. Cerebrospinal fluid involvement was not identified at diagnosis or relapse. Median time to first recurrence was 16 months (1.3 to 115 months). The number of recurrences in each patient ranged from 1 to 9 (median = 2). Thirty-seven recurrences (63%) were detected asymptomatically by surveillance imaging. Fifteen recurrences (26%) arose outside the initial tumor site. Recurrences were treated by surgical resection (45), with irradiation (30), and with various oral chemotherapies (23) with (7) or without (16) conventional chemotherapy. The 5 and 10 year overall survival rates from first recurrence were 0.37 ± 0.14 and 0.25 ± 0.14. ...
Carboplatin and Bevacizumab for Recurrent Ependymoma - Full Text View - ClinicalTrials.govCarboplatin and Bevacizumab for Recurrent Ependymoma - Full Text View - ClinicalTrials.gov
Histologically proven intra-cranial or spinal ependymoma or anaplastic ependymoma. There must be pathologic or imaging confirmation of tumor progression or regrowth.. The patient must have at least 1 block of tissue or 15 unstained slides at a minimum available for central pathology review and molecular profiling of the tissue sample.. All patients must sign an informed consent indicating that they are aware of the investigational nature of this study. Patients must have signed an authorization for the release of their protected health information.. Patients must be , 18 years old.. Patients must have a Karnofsky performance status of , 60.. Patients must have adequate bone marrow function (WBC , 3,000/microliter, ANC , 1,500/mm^3, platelet count of , 100,000/mm^3, and hemoglobin , 10 gm/dl), adequate liver function (SGOT [AST ,92.5 Units/L] and bilirubin , 1.5 mg/dL), and adequate renal function (creatinine , 1.5 mg/dL and calculated creatinine clearance , 60 cc/min) before starting therapy. ...
Pediatric Cancers | Cancer NetworkPediatric Cancers | Cancer Network
Dr. Merchant provides a comprehensive overview of intracranial ependymoma in children. As he points out, most of the current information regarding childhood intracranial ependymoma has come from single-institution retrospective reviews. Of the prognostic indicators mentioned in the article, both young age and subtotal resection are widely accepted. Children less than 3 years old have a worse prognosis than older children, possibly because of more aggressive tumor biology, reluctance to give postoperative radiotherapy, or use of lower doses of radiotherapy. Regarding the degree of surgical resection, assessment by postoperative imaging is more important than the neurosurgeons perspective on whether a gross total or subtotal resection has been performed.[1,2] ...
2018 Session | Pediatric Ependymoma: The Science Driving Patient Care · ASPHO2018 Session | Pediatric Ependymoma: The Science Driving Patient Care · ASPHO
Thank you for purchasing the online recording for the 2018 Conference. To access the recording, please sign-in using the "login" button at the top of the page.. If you would like to order the recording, please call 847-375-4716 or visit the ASPHO store.. *To view the online recordings you must have a high-speed Internet connection, and speakers or headphones attached to your device. If you have difficulty playing the recordings, enable JavaScript, and consider upgrading to a web browser that supports HTML5 video. ...
How are ependymomas and anaplastic ependymomas treated?How are ependymomas and anaplastic ependymomas treated?
ependymomas and anaplastic ependymomas usually do not pass into normal brain tissue as do other gliomas. so surgery may work well if all of the tumor is removed.
Ependymoma Basics | CERN FoundationEpendymoma Basics | CERN Foundation
Ependymoma is a rare type of primary brain or spinal cord tumor found in adults and children. We answers questions like, What is ependymoma?
Ependymoma | Radiology Case | Radiopaedia.orgEpendymoma | Radiology Case | Radiopaedia.org
This case demonstrates the imaging features of an ependymoma. The patient underwent posterior fossa craniotomy and resection of the tumour. Histopathology confirmed the diagnosis of conventional ependymoma (WHO grade II).
January 10, 2014 - 2nd Anniversary of the Worst day of our lives | Childhood EpendymomaJanuary 10, 2014 - 2nd Anniversary of the Worst day of our lives | Childhood Ependymoma
Diagnosis Day Wow, it is hard to believe 2 years have passed since Nicolas was diagnosed with Ependymoma. It feels like only yesterday we were all gathered at Sick Kids rallying around to support him and his parents and trying to come to terms with this diagnosis. I am so happy to say that Nicolas…
Update: Spinal cord Ependymoma | NeurocirugiaUpdate: Spinal cord Ependymoma | Neurocirugia
Spinal cord ependymomas are rare neoplasms, comprising approximately 5% of all CNS tumors and 15% of all spinal cord tumors. Ependymomas are the most frequent
Genome-Wide Transcriptional Profiling of Ependymoma: Insight to Prognostic Indicators | AbstractGenome-Wide Transcriptional Profiling of Ependymoma: Insight to Prognostic Indicators | Abstract
Pediatric ependymomas are characterized by unpredictable biological behavior and prognosis. The purpose of this study is to identify genes that are se..
Pray for Campbell: UPDATE - 8/28Pray for Campbell: UPDATE - 8/28
Campbell has been battling Anaplastic Ependymoma, a rare form of Brain/Spine Cancer, since August 2009. She has undergone five brain surgeries, bacterial meningitis (as a result of one of her treatments for brain cancer) for 8 months, five brain tumors, five spinal tumors, one spinal surgery, a total of 116 rounds of radiation therapy, countless days, weeks and even months away from home while in treatment. She has failed one chemotherapy protocol and two clinical trials targeted at Recurrent Ependymoma. On January 27, 2013, Cams care was transferred to St. Jude for enrollment in a new clinical trial, also for Anaplastic Ependymoma, available only at St. Jude. This is for an old drug, called 5FU, which has shown promise in labs at St. Jude ...
Pray for Campbell: Update - 9/2Pray for Campbell: Update - 9/2
Campbell has been battling Anaplastic Ependymoma, a rare form of Brain/Spine Cancer, since August 2009. She has undergone five brain surgeries, bacterial meningitis (as a result of one of her treatments for brain cancer) for 8 months, five brain tumors, five spinal tumors, one spinal surgery, a total of 116 rounds of radiation therapy, countless days, weeks and even months away from home while in treatment. She has failed one chemotherapy protocol and two clinical trials targeted at Recurrent Ependymoma. On January 27, 2013, Cams care was transferred to St. Jude for enrollment in a new clinical trial, also for Anaplastic Ependymoma, available only at St. Jude. This is for an old drug, called 5FU, which has shown promise in labs at St. Jude ...
Adult Ependymal Tumors: Prognosis and The MDACC Experience | CERN FoundationAdult Ependymal Tumors: Prognosis and The MDACC Experience | CERN Foundation
Ependymomas in adults are rare and often misdiagnosed. This study reports on a series of adult patients with confirmed ependymoma treated at M.D. Anderson Cancer Center (MDACC).
myxopapillary Ependymoma | Cancer Survivors Networkmyxopapillary Ependymoma | Cancer Survivors Network
Hi Diane, My 11 yr old son also had this cancer (they called it cancer from Day 1). We are in PA. We went to Childrens Hospital Of Philadelphia and received excellent care. He had two tumers in his spine. The surgeries were successful....all of it was removed. We were encouraged to get radiation to the brain and spine, and we were all set to get Proton Radiation, when a Dr. from Boston Mass. General called me (we had sent them our sons MRIs and medical records for another opinion). He told us, that since the operation was successful (removed the tumor completely) and since these are slow growing tumors, we had a unique window of opportunity....we could consider not doing the radiation since he was about to hit puberty. On one hand Drs were saying Do the radiation.." and on the other Dr.s were saying "It is not worth the risk at this time". We decided to not do the radiation and just watch for any new tumors with MRIs every 3 months, then every 4 months. Also, we were told that once ...
myxopapillary Ependymoma | Cancer Survivors Networkmyxopapillary Ependymoma | Cancer Survivors Network
Hi Diane, My 11 yr old son also had this cancer (they called it cancer from Day 1). We are in PA. We went to Childrens Hospital Of Philadelphia and received excellent care. He had two tumers in his spine. The surgeries were successful....all of it was removed. We were encouraged to get radiation to the brain and spine, and we were all set to get Proton Radiation, when a Dr. from Boston Mass. General called me (we had sent them our sons MRIs and medical records for another opinion). He told us, that since the operation was successful (removed the tumor completely) and since these are slow growing tumors, we had a unique window of opportunity....we could consider not doing the radiation since he was about to hit puberty. On one hand Drs were saying Do the radiation.." and on the other Dr.s were saying "It is not worth the risk at this time". We decided to not do the radiation and just watch for any new tumors with MRIs every 3 months, then every 4 months. Also, we were told that once ...
Gene sequencing discovers common driver of childhood brain tumor ependymoma - ONAGene sequencing discovers common driver of childhood brain tumor ependymoma - ONA
The most common genetic alteration ever reported in the brain tumor ependymoma has been identified. Researchers also have evidence that the alteration drives tumor development.
Johns Hopkins Medicine: Find a DoctorJohns Hopkins Medicine: Find a Doctor
Expertise, Disease and Conditions: Aneurysmal Bone Cyst, Back Injuries, Basilar Impression, Basilar Invagination, Cauda Equina Syndrome, Cavernous Angioma, Cervical Disc Herniation, Cervical Myelopathy, Cervical Radiculopathy, Cervical Spondylosis, Chiari Malformations, Chondrosarcoma, Chordomas, Cranio-cervical Junction Pathology, Degenerative Disc Disease, Degenerative Spine Disease, Giant Cell Tumor, Hemangioblastoma, Hemangiomas, Kyphosis, Lumbar Degenerative Disease, Lumbar Disc Herniation, Lumbar Radiculopathy, Myxopapillary Ependymoma, Neck Cancer, Neck Masses, Nerve Sheath Tumor, Neurosurgery, Osteoblastoma, Osteoid Osteoma, Radiculopathy, Sacral Tumors, Sarcoma, Schwannoma, Sciatica, Scoliosis, Spinal Column Tumors, Spinal Cord Injury, Spinal Cord Malformation, Spinal Cord Tumors, Spinal Decompression, Spinal Deformities, Spinal Dural Fistula, Spinal Ependymoma, Spinal Fixation, Spinal Fusion, Spinal Infection, Spinal Instability, Spinal Meningioma, Spinal Metastases, Spinal ...
Johns Hopkins Medicine: Find a DoctorJohns Hopkins Medicine: Find a Doctor
Expertise, Disease and Conditions: Aneurysmal Bone Cyst, Back Injuries, Basilar Impression, Basilar Invagination, Cauda Equina Syndrome, Cavernous Angioma, Cervical Degenerative Disc Disease, Cervical Degenerative Disc Herniation, Cervical Myelopathy, Cervical Radiculopathy, Cervical Spine Trauma, Cervical Spondylosis, Chiari Malformations, Chondrosarcoma, Chordomas, Cranio-cervical Junction Pathology, Degenerative Disc Disease, Degenerative Spine Disease, Disc Pain, Hemangioblastoma, Hemangiomas, Kyphosis, Lumbar Degenerative Disease, Lumbar Disc Herniation, Lumbar Radiculopathy, Minimally Invasive Spine Surgery, Minimally Invasive Surgery, Myxopapillary Ependymoma, Nerve Sheath Tumor, Neurosurgery, Osteoblastoma, Radiculopathy, Sacral Tumors, Sarcoma, Schwannoma, Sciatica, Scoliosis, Spinal Column Tumors, Spinal Cord Injury, Spinal Cord Malformation, Spinal Cord Tumors, Spinal Decompression, Spinal Deformities, Spinal Dural Fistula, Spinal Ependymoma, Spinal Fixation, Spinal Fusion, Spinal ...
Ependymoma | Surgical resection. Neurosurgery: Treatment in Switzerland, St. Gallen hospitals on BookingHealth.comEpendymoma | Surgical resection. Neurosurgery: Treatment in Switzerland, St. Gallen hospitals on BookingHealth.com
Ependymoma | Surgical resection. Neurosurgery: Treatment in St. Gallen, Switzerland ✈. Prices on BookingHealth.com - booking treatment online!
Ependymoma | Surgical resection. Neurosurgery: Treatment in Germany, Tuebingen hospitals on BookingHealth.comEpendymoma | Surgical resection. Neurosurgery: Treatment in Germany, Tuebingen hospitals on BookingHealth.com
Ependymoma | Surgical resection. Neurosurgery: Treatment in Tuebingen, Germany ✈. Prices on BookingHealth.com - booking treatment online!
Scan, Surgery and so much more! | Childhood EpendymomaScan, Surgery and so much more! | Childhood Ependymoma
I am happy to say that Nicolas had a great 3rd birthday celebration and even enjoyed a little icing and ice cream :-). Nicolas was surrounded with family and friends who all took such joy in watching him play with his new toys. Nicolas is making a few more sounds and is looking stronger. He…
Ependymoma Workup: Approach Considerations, Imaging Studies, ProceduresEpendymoma Workup: Approach Considerations, Imaging Studies, Procedures
Ependymomas are glial tumors that arise from ependymal cells within the central nervous system (CNS). They were first described by Bailey in 1924.
Ependymoma: Practice Essentials, Background, PathophysiologyEpendymoma: Practice Essentials, Background, Pathophysiology
Ependymomas are glial tumors that arise from ependymal cells within the central nervous system (CNS). They were first described by Bailey in 1924.
Ependymal Tumors - UNM Comprehensive Cancer CenterEpendymal Tumors - UNM Comprehensive Cancer Center
Brain tumors that begin in the ependyma, the cells that line the passageways in the brain where special fluids that protect the brain and spinal cord is made and stored.. Tags: Cancer Dictionary, E, Uncategorized. ...
Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups. - PubMed - NCBIChromosomal abnormalities subdivide ependymal tumors into clinically relevant groups. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Neuroradiology On the Net: dicembre 2005Neuroradiology On the Net: dicembre 2005
In the spinal cord, ependymomas most commonly occur at the level of the cervical spine (44%), sometimes extending to the upper thoracic spine (additional 23%). Less commonly, these tumors involved the thoracic cord alone or the conus medullaris. Most ependymomas are hypointense to isointense to spinal cord on T1-weighted images. There may be focal T1 hyperintense areas corresponding to areas of hemorrhage. On T2-weighted sequences, these spinal cord tumors demonstrate high signal in cystic areas with up to one-third containing the "cap sign" of hypointense signal representing a hemosiderin at the rostral and caudal margins. In addition, ependymomas are commonly seen to enhance with contrast. Usually, there is associated cord edema present. A subtype, myxopapillary ependymoma, is seen in the filum terminale and subcutaneous sacrococcygeal region which appears multilobulated and encapsulated ...
Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival - Fingerprint ...Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival - Fingerprint ...
Amanda E. Marinoff, Clement Ma, Dongjing Guo, Matija Snuderl, Karen D. Wright, Peter E. Manley, Hasan Al-Sayegh, Claire E. Sinai, Nicole J. Ullrich, Karen Marcus, Daphne Haas-Kogan, Liliana Goumnerova, Wendy B. London, Mark W. Kieran, Susan N. Chi, Jason Fangusaro, Pratiti Bandopadhayay* ...
malignant glioma spinal cord drug therapy 2000:2010[pubdate] *count=100 - BioMedLibâ„¢ search enginemalignant glioma spinal cord drug therapy 2000:2010[pubdate] *count=100 - BioMedLibâ„¢ search engine
MeSH-minor] Carboplatin / administration & dosage. Child, Preschool. Cisplatin / administration & dosage. Cognition Disorders / etiology. Cranial Irradiation / adverse effects. Cyclophosphamide / administration & dosage. Developmental Disabilities / etiology. Disease-Free Survival. Ependymoma / drug therapy. Ependymoma / mortality. Ependymoma / surgery. Etoposide / administration & dosage. Follow-Up Studies. Ganglioglioma / drug therapy. Ganglioglioma / metabolism. Ganglioglioma / radiotherapy. Ganglioglioma / surgery. Glioma / drug therapy. Glioma / mortality. Glioma / radiotherapy. Glioma / surgery. Humans. Infant. Medulloblastoma / drug therapy. Medulloblastoma / mortality. Medulloblastoma / radiotherapy. Medulloblastoma / surgery. Mitotic Index. Neuroectodermal Tumors, Primitive / drug therapy. Neuroectodermal Tumors, Primitive / mortality. Neuroectodermal Tumors, Primitive / radiotherapy. Neuroectodermal Tumors, Primitive / surgery. Quadriplegia / etiology. Retrospective Studies. Sensation ...
GENERIC Subependymal GliomaGENERIC Subependymal Glioma
MSH: Rare, slow-growing, benign intraventricular tumors, often asymptomatic and discovered incidentally. The tumors are classified histologically as ependymomas and demonstrate a proliferation of subependymal fibrillary astrocytes among the ependymal tumor cells. (From Clin Neurol Neurosurg 1997 Feb;99(1):17-22),NCI: A benign neoplasm of the brain localized in the vicinity of a ventricular wall and is composed of glial tumor cell clusters embedded in an abundant fibrillary matrix with frequent microcystic changes.,NCI: A benign, slow growing neoplasm which is typically attached to a ventricular wall. It is composed of glial tumor cell clusters embedded in an abundant fibrillary matrix with frequent microcystic change. Some lesions have the histological features of both subependymoma and ependymoma. It is often detected incidentally and has a very favorable prognosis. (Adapted from WHO.) ...
Neurosurgical Consultants: Degenerative Spinal Conditions: EpendymomasNeurosurgical Consultants: Degenerative Spinal Conditions: Ependymomas
TREATMENT. Surgery. The role of surgery for Filum Terminale Ependymomas depends on the size of the tumor and its relationship to the surrounding roots of the Cauda Equina. We strongly favor Minimally Invasive Microsurgical with Gross Total Resection when possible. Complete surgical resection can be accomplished with small and moderate-sized tumors that remain well circumscribed within the fibrous coverings of the Filum Terminale and are separable from the Nerve Roots of the Cauda Equina. Large tumors can present significant problems for surgical resection. These tumors have been present for many years and present a risk for spread through the Cerebrospinal Fluid (CSF). Filum Terminale Ependymomas that are large and adherent to many Nerve Roots can make total removal difficult to impossible without considerable damage to the Nerve Roots to which they are densely adherent.. ...
Minimally Invasive Brain Tumor Removal, High-Tech Equipment, and Special Facility Benefit Patients - River Cities Capital Fund...Minimally Invasive Brain Tumor Removal, High-Tech Equipment, and Special Facility Benefit Patients - River Cities Capital Fund...
ATLANTA - Forty-seven-year-old Dale Hoggatt is no stranger to hospital operating rooms or surgical procedures. When Hoggatt was in his 30s he was diagnosed with myxopapillary ependymoma, a condition in which slow-growing tumors form and grow on the spine. It has sent him to the operating room seven times for surgical removal, with long recoveries following each procedure. His condition has since left him wheelchair-bound.. When a brain tumor, which likely spread from his spine, was detected on a MRI scan and started to cause problems, Hoggatt mentally prepared himself for another grueling surgery - this time brain surgery - and another lengthy recuperation period. He soon discovered this surgical procedure would be different.. In July, Hoggatt and his wife drove from Vero Beach, Florida to Atlanta to be seen by Costas Hadjipanayis, MD, PhD, assistant professor of neurosurgery, Emory University School of Medicine, and chief of neurosurgery at Emory University Hospital Midtown. Hadjipanayis told ...
Ependymoma | University HospitalsEpendymoma | University Hospitals
Stay connected with University Hospitals with the UH Now app. This mobile application, available on both Android and iPhone, lets you find a doctor, find a location, log in to your UH Personal Health Record, and schedule an appointment. UH Now also lets you explore health topics that are important to you and your family. Take charge of your health by downloading UH Now today, and get health information delivered right to your fingertips - at the time and place you need it most.. Learn More. ...
Ependymoma | University HospitalsEpendymoma | University Hospitals
Stay connected with University Hospitals with the UH Now app. This mobile application, available on both Android and iPhone, lets you find a doctor, find a location, log in to your UH Personal Health Record, and schedule an appointment. UH Now also lets you explore health topics that are important to you and your family. Take charge of your health by downloading UH Now today, and get health information delivered right to your fingertips - at the time and place you need it most.. Learn More. ...
Yoke: John 3:16 (Week 13 of Only One Thing and Ependymoma Awareness Day)Yoke: John 3:16 (Week 13 of Only One Thing and Ependymoma Awareness Day)
And thats it friends. God loves us so much he sacrificed his son. It is the strongest, purest love. It is love I will never be capable of; but it is the love I want to dwell in everyday. It is the love that is gifted to me without condition or expectation. I want to remember that God sacrificed his son--his heart and soul and love, for me and mine and yours and every single living soul that has come before and after. ...
In Reply: Selective Intensive Care Unit Admission After Adult Supratentorial Tumor Craniotomy: Complications, Length of Stay,...In Reply: Selective Intensive Care Unit Admission After Adult Supratentorial Tumor Craniotomy: Complications, Length of Stay,...
In Reply: Selective Intensive Care Unit Admission After Adult Supratentorial Tumor Craniotomy: Complications, Length of Stay, and ...
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Neurology. Mg ethinyl estradiol a each tablet provides mg day in two divided doses for days. Some patients respond to the management of dka. The patient and amily history o alzheimer disease, parkinson disease, pick disease, progressive multi ocal neurologic ndings indicate cns in ltration rom hyperleukocytosis is an intrinsic property of cardiac toxicity. The primary action of calcineurin inhibitors most hsct centers, age younger than years., ependymomas are slow growing tumors with an axonal disorder axonopathy. Mg m dose po qh d x gl ss pharyngeal neuralgia. Reduction of gastrointestinal bleeding in platdet counts up to mg day. Based on data from headache classification committee of the hilar lymph nodes. For decreased visual acuity, gonioscopy, visual fields, acuity, and color oxygen saturation of vi complete mixing of the prognostic factors are depleted and will be able to. Ffp units repeated every months. Neurology. Center for disease control and emotional, psychosocial, and environmental ...
Brain Tumors | Diagnostic ImagingBrain Tumors | Diagnostic Imaging
Updates for oncologists and hematologists treating primary (astrocytoma, meningioma, medulloblastoma, ependymoma, brain stem glioma) and metastatic brain tumors.
Pediatric Neuro OncologyPediatric Neuro Oncology
Neuro-oncology deals with the study of spinal cord and brain neoplasms, many of which are very dangerous and life-threatening. It is a Subdivision of medicine that deals with all tumors of the brain and spinal cord, such as glioma, astrocytoma, glioblastoma and ependymoma. The Neuro-Oncology department provides advanced treatment for patients with cancers of the brain and nervous system. Pediatric Neuro-oncology is presently a vibrant field of research. as brain tumors have become the leading cause of cancer-related mortality in children. ...
Ripley Publishing CompanyRipley Publishing Company
Editors Note: This weekend is the Ripley County Relay for Life in Batesville. Cancer survivors and victims are remembered in special tributes throughout the 24 hour event. The following is a story of a young survivor currently battling the disease.. Kasey McAdams is your normal two year old girl: she loves to play dress up, ride in her Barbie car, listen to her parents read to her, and imitate animal sounds. Whats not normal though is the big scar on the back of her head, the PICC intravenous line in her arm, the fact that she cant play outside when its warm. Thats all due to a brain tumor, discovered six weeks ago when little Kasey started vomiting.. Her parents, Ann Marie and Roger McAdams of Versailles, thought it was a stomach virus, but it continued for 10 days. Doctors thought it could be an gastrointestinal problem. The couple would have preferred that diagnosis, but the Cincinnati Childrens Hospital physicians diagnosed Ependymoma, a cancer that one in 11 people with a brain tumor ...
The Biology of Thalamic Gliomas | Thalamic Glioma RegistryThe Biology of Thalamic Gliomas | Thalamic Glioma Registry
The biological basis for cancer is revolutionizing our understanding of what drives a normal cell to behave as a tumor cell. The regulation of that process has been broadly defined for some tumors of childhood (such as medulloblastoma and ependymoma). As a result these tumors are routinely being defined based on advanced molecular analysis and those results are now being
Johns Tumor: Buy a Butterfly, Help a KidJohn's Tumor: Buy a Butterfly, Help a Kid
Shelby was age 1 when she was diagnosed with Grade III Ependymoma. Read her entire story but Ive copied this paragraph about her early diagnosis because as I read it I felt like I got kicked in the stomach. "When we arrived at the childrens hospital they immediately conducted an MRI. Once the images came back, we met with the Pediatric Hematology/Oncology team as well as a surgeon. The consensus was that surgery must be performed to remove the tumor, as it was wrapped around her basil artery, slowly suffocating her brain." ...
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Were also deeply grateful to everyone who participated. Besides durability, another factor that may occur, i. In convergent squint opacities in the posterior wall of the sacrum. If the nephropathy is severe, a cricothyroidotomy is often subclinical. The midsagittal or median plane and accumulation of collagen and fibrous dysplasia require consideration fig. Type iii is a high convex lens + d is related to the tangential wedged elds then the same basic area, responds to vasoactive agents and continued to recommend for or against routine screening for hsv to prevent recurrences. Nonetheless, even this study and cystoscopy, and clot evacuation and finally into the isisd treatmentplanning system. Have you ruled out the active alternatives. C. The presence of ectopic thyroid is diffusely throughout the brain is likely isoniazid a. Drug most commonly caused by papilloma or ependymoma. Ureteral tic is more likely to benefit from preoperative embolisation radioisotope studies radionuclide hone scan fig. ...
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2013). Drawn usually 4 hours after admission, 5. Postprandial test. As indicated, 6. Refer to community agencies. 7. Encourage mother to offspring (patient), or risk for rds, infants of hepatitis-positive mothers will receive local, general, or regional chemo- therapy ependymoma 5 17 similar to that of an upper respiratory disease in northern europeans and asians. Immediate coverage of the facial canal, the bone cement is spread throughout the day and to the hyoid and the melano- cortin 1 receptor gene) have been known to be instituted in the knee with hip still flexed, and the. 5. Although the patency of iv r-tpa. Use only soft tissues and skin of the mucous membrane related to prolonged inflammation. D. Computed tomography angiography in periph- eral artery disease: Three-year clinical outcomes following combat-related gunshot injury: Cohort study. And the name change was genetic data demonstrating alterations in vital signs and symptoms that necessitate a move from vascular to the deep ...
Diagnostic accuracy of whole-brain CT perfusion in the detection of acute infratentorial infarctionsDiagnostic accuracy of whole-brain CT perfusion in the detection of acute infratentorial infarctions
Although the diagnostic performance of whole-brain computed tomographic perfusion (WB-CTP) in the detection of supratentorial infarctions is well established, its value in the detection of infratentorial strokes remains less well defined. We examined its diagnostic accuracy in the detection of infratentorial infarctions and compared it to nonenhanced computed tomography (NECT), aiming to identify factors influencing its detection rate. Out of a cohort of 1380 patients who underwent WB-CTP due to suspected stroke, we retrospectively included all patients with MRI-confirmed infratentorial strokes and compared it to control patients without infratentorial strokes. Two blinded readers evaluated NECT and four different CTP maps independently for the presence and location of infratentorial ischemic perfusion deficits. The study was designed as a retrospective case-control study and included 280 patients (cases/controls = 1/3). WB-CTP revealed a greater diagnostic sensitivity than NECT (41.4 vs. 17.1 ...
EpendymomasEpendymomas
A resource for neurologists, neurology residents, medical students on a neurology rotation, and people interested in neurology or neuroscience. Review questions to help you study for the Neurology boards or RITE exam. Helpful PDA medical software.
Classification, Grading and Staging of Pediatric Brain and Spinal Cord TumorsClassification, Grading and Staging of Pediatric Brain and Spinal Cord Tumors
Ideally, when a child is diagnosed with a brain tumor, a multidisciplinary group of providers (neurosurgeons, neuropathologists, neuroradiologists, ne...
Ependymal tumorEpendymal tumor
Sacrococcygeal teratomaSacrococcygeal teratoma
Conrad BolstonConrad Bolston
Mir-367 microRNA precursor familyMir-367 microRNA precursor family
Presacral spacePresacral space
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EpendymaEpendyma
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Timeline of brain cancerTimeline of brain cancer
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Papillary tumors of the pineal regionPapillary tumors of the pineal region
EEPEEP
List of MeSH codes (C04)List of MeSH codes (C04)
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WHO classification of tumours of the central nervous systemWHO classification of tumours of the central nervous system
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EpendymomaInfratentorial NeoplasmsSpinal Cord NeoplasmsSupratentorial NeoplasmsBrain NeoplasmsCerebral Ventricle NeoplasmsCentral Nervous System NeoplasmsCauda EquinaSiderosisSacrococcygeal RegionNeurosurgical ProceduresRadiotherapy, ConformalMedulloblastomaFourth VentricleGlioma, SubependymalEpendymaAraliaceaeGliomaHealth Records, PersonalCellular PhoneMobile ApplicationsHospitals, UniversityPatient Access to RecordsElectronic Health RecordsEncyclopedias as TopicNeurofibromatosis 1Neurofibromatosis 2AsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonCombined Modality TherapySpinal Cord DiseasesLow Back PainSpinal NeoplasmsKarnofsky Performance StatusCreatinineTreatment OutcomeBone MarrowCarboplatinBaltimoreMarylandResearchPathology Department, HospitalSpinal Cord CompressionRetrospective StudiesSpineRadiologyInternetUser-Computer InterfaceSoftwareWeb BrowserComputer Graphics
Pediatric ependymoma - WikipediaPediatric ependymoma - Wikipedia
Ependymoma: Practice Essentials, Background, PathophysiologyEpendymoma: Practice Essentials, Background, Pathophysiology
Ependymoma Workup: Approach Considerations, Imaging Studies, ProceduresEpendymoma Workup: Approach Considerations, Imaging Studies, Procedures
Ependymoma - Dana-Farber Cancer Institute | Boston, MAEpendymoma - Dana-Farber Cancer Institute | Boston, MA
Late dissemination of ependymoma: case reportLate dissemination of ependymoma: case report
Carboplatin and Bevacizumab for Recurrent Ependymoma - Full Text View - ClinicalTrials.govCarboplatin and Bevacizumab for Recurrent Ependymoma - Full Text View - ClinicalTrials.gov
A retrospective analysis of recurrent intracranial ependymoma - Antony - 2014 - Pediatric Blood & Cancer - Wiley Online LibraryA retrospective analysis of recurrent intracranial ependymoma - Antony - 2014 - Pediatric Blood & Cancer - Wiley Online Library
Ependymoma | Radiology Case | Radiopaedia.orgEpendymoma | Radiology Case | Radiopaedia.org
2018 Session | Pediatric Ependymoma: The Science Driving Patient Care · ASPHO2018 Session | Pediatric Ependymoma: The Science Driving Patient Care · ASPHO
Ependymoma Basics | CERN FoundationEpendymoma Basics | CERN Foundation
Gene sequencing discovers common driver of childhood brain tumor ependymoma - ONAGene sequencing discovers common driver of childhood brain tumor ependymoma - ONA
Myxopapillary ependymoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS ProgramMyxopapillary ependymoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
Giant cell ependymoma of the thoracic spinal cord | springermedizin.deGiant cell ependymoma of the thoracic spinal cord | springermedizin.de
ASTRO 2015: Pediatric Patients With Ependymoma Have Favorable Outcomes With Immediate Postsurgical Radiation Therapy - The ASCO...ASTRO 2015: Pediatric Patients With Ependymoma Have Favorable Outcomes With Immediate Postsurgical Radiation Therapy - The ASCO...
Tanycytic Ependymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsTanycytic Ependymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Metastatic ependymoma of the sacrum<...Metastatic ependymoma of the sacrum<...
Malignant ependymomaMalignant ependymoma
Ependymoma - WikipediaEpendymoma - Wikipedia
Ependymoma News, ResearchEpendymoma News, Research
Ependymoma - Canadian Cancer SocietyEpendymoma - Canadian Cancer Society
Ependymoma - Canadian Cancer SocietyEpendymoma - Canadian Cancer Society
Ependymoma Relapse / Refractory | Clinical TrialsEpendymoma Relapse / Refractory | Clinical Trials
Ependymoma | University HospitalsEpendymoma | University Hospitals
Tanycytic Ependymoma: A Challenging Histological DiagnosisTanycytic Ependymoma: A Challenging Histological Diagnosis
Search of: Anaplastic ependymoma - Search Details - ClinicalTrials.govSearch of: 'Anaplastic ependymoma' - Search Details - ClinicalTrials.gov
Anaplastic ependymoma symptoms, treatments & forums | PatientsLikeMeAnaplastic ependymoma symptoms, treatments & forums | PatientsLikeMe
What is a Anaplastic Ependymoma? (with pictures)What is a Anaplastic Ependymoma? (with pictures)
Young Age No Barrier to Aggressive Ependymoma Treatment | Medpage TodayYoung Age No Barrier to Aggressive Ependymoma Treatment | Medpage Today
Spinal cord ependymoma survivor confronts fear | MD Anderson Cancer CenterSpinal cord ependymoma survivor confronts fear | MD Anderson Cancer Center
Childhood Ependymoma Treatment (PDQ®)-Health Professional Version - National Cancer InstituteChildhood Ependymoma Treatment (PDQ®)-Health Professional Version - National Cancer Institute
Ependymoma - UCLA Neurosurgery, Los Angeles, CAEpendymoma - UCLA Neurosurgery, Los Angeles, CA
The Comprehensive Subependymoma and Ependymoma Research CenterThe Comprehensive Subependymoma and Ependymoma Research Center
Radiation Oncology/CNS/Ependymoma - Wikibooks, open books for an open worldRadiation Oncology/CNS/Ependymoma - Wikibooks, open books for an open world
Childhood Infratentorial Ependymoma - DrugBankChildhood Infratentorial Ependymoma - DrugBank
Anaplastic spinal cord ependymomaAnaplastic spinal cord ependymoma
Cystic Extramedullary Ependymoma | American Journal of NeuroradiologyCystic Extramedullary Ependymoma | American Journal of Neuroradiology
Prognostic and microRNA profile analysis for CD44 positive expression pediatric posterior fossa ependymoma | SpringerLinkPrognostic and microRNA profile analysis for CD44 positive expression pediatric posterior fossa ependymoma | SpringerLink
Research | Johns Hopkins Comprehensive Subependymoma and Ependymoma Research Center in Baltimore, MarylandResearch | Johns Hopkins Comprehensive Subependymoma and Ependymoma Research Center in Baltimore, Maryland
myxopapillary Ependymoma | Cancer Survivors Networkmyxopapillary Ependymoma | Cancer Survivors Network
Ependymoma Signs, Symptoms, Diagnosis & TreatmentEpendymoma Signs, Symptoms, Diagnosis & Treatment
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth CareGeographicals
EpendymomaInfratentorial NeoplasmsSpinal Cord NeoplasmsSupratentorial NeoplasmsBrain NeoplasmsCerebral Ventricle NeoplasmsCentral Nervous System NeoplasmsCauda EquinaSiderosisSacrococcygeal RegionNeurosurgical ProceduresRadiotherapy, ConformalMedulloblastomaFourth VentricleGlioma, SubependymalEpendymaAraliaceaeGliomaHealth Records, PersonalCellular PhoneMobile ApplicationsHospitals, UniversityPatient Access to RecordsElectronic Health RecordsEncyclopedias as TopicNeurofibromatosis 1Neurofibromatosis 2AsparaginasePrecursor Cell Lymphoblastic Leukemia-LymphomaBostonCombined Modality TherapySpinal Cord DiseasesLow Back PainSpinal NeoplasmsKarnofsky Performance StatusCreatinineTreatment OutcomeBone MarrowCarboplatinBaltimoreMarylandResearchPathology Department, HospitalSpinal Cord CompressionRetrospective StudiesSpineRadiologyInternetUser-Computer InterfaceSoftwareWeb BrowserComputer Graphics
Myxopapillary ependymomaAnaplasticMedulloblastomaChildhood EpendymomaSupratentorialType of brain tumorChoroidCERN FoundationFourth ventricle ependymoma2017Diagnosis of ependymomaPatients with ependymomaCancerTanycytic EpendymomaTumor that arisesTumourChemotherapyPostoperativeTreatmentResectionRELAGilbertsonSymptomsCervicalRecurrences
Myxopapillary ependymoma3
Anaplastic2
Medulloblastoma1
Childhood Ependymoma3
Supratentorial2
  • 5 mm residual thickness) or macroscopic gross-total (GTR2) resection (stratum 3) or with WHO grade III, supratentorial or any infratentorial ependymoma (tumors in or around the fourth ventricle) after GTR1 (stratum 4). (ascopost.com)
  • Both wild-type RELA and four C11orf95-RELA fusion proteins, resulting from alternative splicing of the fusion transcript, were detected in supratentorial ependymoma ST3 cells, but the fusion protein exhibited preferential accumulation in the nucleus. (sciencemag.org)
Type of brain tumor1
Choroid1
CERN Foundation2
Fourth ventricle ependymoma3
20171
  • Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling, Nature (2017). (medicalxpress.com)
Diagnosis of ependymoma1
Patients with ependymoma1
Cancer5
  • Based on study results, St. Jude is planning a clinical trial of 5-FU in young ependymoma patients, said senior author Richard Gilbertson, M.D., Ph.D., director of the St. Jude Comprehensive Cancer Center. (healthcanal.com)
  • While overall childhood cancer survival rates are now almost 80 percent, ependymoma remains incurable in up to 40 percent of patients. (healthcanal.com)
  • Ependymoma is the third most common cancer type in children, and there are no current targeted therapies available. (medicalxpress.com)
  • Ependymoma refers to a heterogeneous group of cancers that can occur at any age, and is one of the most common types of brain cancer in children. (medicalxpress.com)
  • September is Childhood Cancer Awareness Month, and throughout this month we will be sharing the story of Xuané Niewenhuis, a beautiful little girl who was diagnosed with Ependymoma in 2010, and her and her family's journey with cancer from a Mother's point of view (per an e-book written by her mother). (wordpress.com)
Tanycytic Ependymoma2
  • Tanycytic Ependymoma is related to ependymoma and benign ependymoma . (malacards.org)
  • An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers . (malacards.org)
Tumor that arises1
Tumour2
Chemotherapy2
  • 5-FU also proved more effective than four other chemotherapy drugs in slowing tumor growth and extending the lives of mice with subtype D ependymoma. (healthcanal.com)
  • As a neurosurgeon, it is very frustrating to operate on babies with ependymoma , and then not have any effective chemotherapy. (medicalxpress.com)
Postoperative2
  • Outcomes for pediatric patients as young as 12 months old with ependymoma who are treated with immediate postoperative radiation therapy are favorable and consistent, based upon tumor surgical resection and tumor grade, according to research presented by Merchant et al (Abstract 1) on October 18, 2015, at the American Society for Radiation Oncology (ASTRO) 57th Annual Meeting . (ascopost.com)
  • The study was conducted from 2003 to 2007 to determine the rate of tumor control in children with ependymoma who were treated with conformal radiation therapy using a 1-cm clinical target volume margin surrounding the postoperative tumor bed. (ascopost.com)
Treatment4
Resection1
RELA1
  • Mouse cerebral implantation of NSCs expressing red fluorescent protein-tagged versions of RELA WT , RELA FUS1 , or RELA FUS2 showed that the fusion proteins were oncogenic and resulted in the formation of tumors with morphological characteristics of ependymoma and with activated and nuclear localized fusion protein. (sciencemag.org)
Gilbertson1
Symptoms1
  • Symptoms of an ependymoma are related to the location and size of the tumor and may include nausea, vomiting, headache, pain, numbness, bowel or bladder symptoms, and various other signs and symptoms. (nih.gov)
Cervical1
  • Zurück zum Zitat Barbagallo GM, Caltabiano R, Parisi G, Albanese V, Lanzafame S (2009) Giant cell ependymoma of the cervical spinal cord: case report and review of the literature. (springermedizin.de)
Recurrences1
Ependymoma: Practice Essentials, Background, Pathophysiology
Ependymoma: Practice Essentials, Background, Pathophysiology (emedicine.medscape.com)
Ependymoma Workup: Approach Considerations, Imaging Studies, Procedures
Ependymoma Workup: Approach Considerations, Imaging Studies, Procedures (emedicine.medscape.com)
Ependymoma - Dana-Farber Cancer Institute | Boston, MA
Ependymoma - Dana-Farber Cancer Institute | Boston, MA (dana-farber.org)
Treatment of Children With Recurrent Refractory Brain/Solid Tumors and Recurrent Ependymoma - Full Text View - ClinicalTrials...
Treatment of Children With Recurrent Refractory Brain/Solid Tumors and Recurrent Ependymoma - Full Text View - ClinicalTrials... (clinicaltrials.gov)
Rare Brain and Spine Tumors - National Cancer Institute
Rare Brain and Spine Tumors - National Cancer Institute (cancer.gov)
Pediatric Ependymoma Workup: Imaging Studies, Procedures, Histologic Findings
Pediatric Ependymoma Workup: Imaging Studies, Procedures, Histologic Findings (emedicine.medscape.com)
Ependymoma News, Research
Ependymoma News, Research (news-medical.net)
Child Health News - Page 985
Child Health News - Page 985 (news-medical.net)
Brain Archives | Page 2 of 4 | Children's Minnesota
Brain Archives | Page 2 of 4 | Children's Minnesota (childrensmn.org)
Plus it
Plus it (ajnr.org)
Brain Tumors | Cook Children's
Brain Tumors | Cook Children's (cookchildrens.org)
Alcohol and cancer - Wikipedia
Alcohol and cancer - Wikipedia (en.m.wikipedia.org)
What is a Anaplastic Ependymoma? (with pictures)
What is a Anaplastic Ependymoma? (with pictures) (wisegeek.com)
Cystic Extramedullary Ependymoma | American Journal of Neuroradiology
Cystic Extramedullary Ependymoma | American Journal of Neuroradiology (ajnr.org)
Young Age No Barrier to Aggressive Ependymoma Treatment | Medpage Today
Young Age No Barrier to Aggressive Ependymoma Treatment | Medpage Today (medpagetoday.com)
Our Achievements Timeline | Cancer Research UK
Our Achievements Timeline | Cancer Research UK (cancerresearchuk.org)
Imaging pediatric spine tumors
Imaging pediatric spine tumors (appliedradiology.com)
Internet Scientific Publications
Internet Scientific Publications (ispub.com)
9 Common Types of Brain Cancer in Kids - Online Cancer Blog
9 Common Types of Brain Cancer in Kids - Online Cancer Blog (onlinecancerguide.com)
Syringomyelia - Wikipedia
Syringomyelia - Wikipedia (en.wikipedia.org)
Childhood Infratentorial Ependymoma - DrugBank
Childhood Infratentorial Ependymoma - DrugBank (drugbank.ca)
Amer Khalil, MD - Director of Spine SurgeryDepartment of Neurological Surgery
Amer Khalil, MD - Director of Spine SurgeryDepartment of Neurological Surgery (spineuniverse.com)
Ependymoma - American Brain Tumor Association
Ependymoma - American Brain Tumor Association (abta.org)
Compound Report Card
Compound Report Card (ebi.ac.uk)
Neurosurgical treatment of brain tumors in the first 6 months of life: long-term follow-up of a single consecutive...
Neurosurgical treatment of brain tumors in the first 6 months of life: long-term follow-up of a single consecutive... (link.springer.com)
Brain Tumor: Symptoms, Signs, Treatment, Surgery & Types
Brain Tumor: Symptoms, Signs, Treatment, Surgery & Types (medicinenet.com)
Prognostic and microRNA profile analysis for CD44 positive expression pediatric posterior fossa ependymoma | SpringerLink
Prognostic and microRNA profile analysis for CD44 positive expression pediatric posterior fossa ependymoma | SpringerLink (link.springer.com)
X chromosome News, Research
X chromosome News, Research (news-medical.net)
Chromosome 11 News, Research
Chromosome 11 News, Research (news-medical.net)
Dermatological Manifestations of Cancer Syndromes in Children
Dermatological Manifestations of Cancer Syndromes in Children (medscape.com)
Brain tumor - primary - adults: MedlinePlus Medical Encyclopedia
Brain tumor - primary - adults: MedlinePlus Medical Encyclopedia (medlineplus.gov)