Pulmonary Eosinophilia
Eosinophils
Angiolymphoid Hyperplasia with Eosinophilia
Interleukin-5
Hypereosinophilic Syndrome
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.
Bronchial Hyperreactivity
Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
Chemokine CCL11
Chemotactic Factors, Eosinophil
Toxocariasis
Eosinophilic Esophagitis
Chronic ESOPHAGITIS characterized by esophageal mucosal EOSINOPHILIA. It is diagnosed when an increase in EOSINOPHILS are present over the entire esophagus. The reflux symptoms fail to respond to PROTON PUMP INHIBITORS treatment, unlike in GASTROESOPHAGEAL REFLUX DISEASE. The symptoms are associated with IgE-mediated hypersensitivity to food or inhalant allergens.
Churg-Strauss Syndrome
Immunoglobulin E
Allergens
Leukocyte Count
Asthma
Respiratory Hypersensitivity
Bronchoalveolar Lavage Fluid
Toxocara canis
Th2 Cells
Lung
Eosinophil Peroxidase
Eosinophil Granule Proteins
Hypersensitivity
Chemokine CCL24
Aspergillosis, Allergic Bronchopulmonary
Trichinellosis
An infection with TRICHINELLA. It is caused by eating raw or undercooked meat that is infected with larvae of nematode worms TRICHINELLA genus. All members of the TRICHINELLA genus can infect human in addition to TRICHINELLA SPIRALIS, the traditional etiological agent. It is distributed throughout much of the world and is re-emerging in some parts as a public health hazard and a food safety problem.
Interleukin-13
Drug Hypersensitivity
Chemokines, CC
Filariasis
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
Eosinophil-Derived Neurotoxin
Strongyloidiasis
Cytokines
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Respiratory Syncytial Virus Vaccines
Interleukin-4
Fasciitis
Inflammation of the fascia. There are three major types: 1, Eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, Necrotizing fasciitis (FASCIITIS, NECROTIZING), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, Nodular/Pseudosarcomatous /Proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma.
Mucus
Eosinophilia-Myalgia Syndrome
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)
Lung Diseases, Parasitic
Drug Eruptions
Angioedema
Respiratory Syncytial Virus Infections
Sputum
Endomyocardial Fibrosis
A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).
Bronchoalveolar Lavage
Diethylcarbamazine
Ascaris
Disease Models, Animal
Larva Migrans, Visceral
Methacholine Chloride
A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
Prednisolone
Leukocyte Disorders
Mastocytosis
Inflammation
Embolism, Cholesterol
Blocking of a blood vessel by CHOLESTEROL-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset.
Mesocestoides
A genus of tapeworm, containing several species, found as adults in birds and mammals. The larvae or cysticercoid stage develop in invertebrates. Human infection has been reported and is probably acquired from eating inadequately cooked meat of animals infected with the second larval stage known as the tetrahythridium.
Nippostrongylus
Drug Hypersensitivity Syndrome
Receptors, CCR3
Eosinophilic Granuloma
Hypersensitivity, Immediate
Parasitic Diseases
Nasal Polyps
Anthelmintics
Phthalic Anhydrides
Bronchial Provocation Tests
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Passive Cutaneous Anaphylaxis
An evanescent cutaneous reaction occurring when antibody is injected into a local area on the skin and antigen is subsequently injected intravenously along with a dye. The dye makes the rapidly occurring capillary dilatation and increased vascular permeability readily visible by leakage into the reaction site. PCA is a sensitive reaction for detecting very small quantities of antibodies and is also a method for studying the mechanisms of immediate hypersensitivity.
Fascioliasis
Respiratory Syncytial Viruses
Intestinal Diseases, Parasitic
Food Parasitology
Injections, Intraperitoneal
Goblet Cells
Pleurisy
Administration, Inhalation
Gnathostoma
Gnathostomiasis
Angiostrongylus cantonensis
Respiratory Syncytial Virus, Human
Job Syndrome
Anti-Allergic Agents
Interleukin-9
Eosinophil Major Basic Protein
Trichuroidea
Basophils
Esophagitis
Toxic oil syndrome mortality: the first 13 years. (1/1319)
BACKGROUND: The toxic oil syndrome (TOS) epidemic that occurred in Spain in the spring of 1981 caused approximately 20000 cases of a new illness. Overall mortality and mortality by cause in this cohort through 1994 are described for the first time in this report. METHODS: We contacted, via mail or telephone, almost every living member of the cohort and family members of those who were known to have died in order to identify all deaths from 1 May 1981 through 31 December 1994. Cause of death data were collected from death certificates and underlying causes of death were coded using the International Classification of Diseases, 9th Revision. RESULTS: We identified 1663 deaths between 1 May 1981 and 31 December 1994 among 19 754 TOS cohort members, for a crude mortality rate of 8.4%. Mortality was highest during 1981, with a standardized mortality ratio (SMR) of 4.92 (95% confidence interval [CI]: 4.39-5.50) compared with the Spanish population as a whole. The highest SMR, (20.41, 95% CI: 15.97-25.71) was seen among women aged 20-39 years during the period from 1 May 1981 through 31 December 1982. Women <40 years old, who were affected by TOS , were at greater risk for death in most time periods than their unaffected peers, while older women and men were not. Over the follow-up period, mortality of the cohort was less than expected when compared with mortality of the general Spanish population, or with mortality of the population of the 14 provinces where the epidemic occurred. We also found that, except for deaths attributed to external causes including TOS and deaths due to pulmonary hypertension, all causes of death were decreased in TOS patients compared to the Spanish population. The most frequent underlying causes of death were TOS, 350 (21.1%); circulatory disorders, 536 (32.3%); and malignancies, 310 (18.7%). CONCLUSIONS: We conclude that while on average people affected by toxic oil syndrome are not at greater risk for death over the 13-year study period than any of the comparison groups, women <40 years old were at greater risk of death. (+info)Eotaxin contributes to renal interstitial eosinophilia. (2/1319)
BACKGROUND: A potent eosinophil chemotactic cytokine, human eotaxin, is directly chemotactic for eosinophils. Therefore, the specific expression of eotaxin in tissue might play a crucial role in tissue eosinophilia. However, the precise molecular mechanism of the recruitment and activation of eosinophils in human renal diseases remains to be investigated. We evaluated the role of eotaxin in the pathogenesis of human diffuse interstitial nephritis with marked infiltration of eosinophils. METHODS: In this study, we examined 20 healthy volunteers. 56 patients with primary or secondary glomerular diseases and two hypereosinophilic syndrome patients without renal involvement. Urinary and serum eotaxin levels were determined by an enzyme-linked immunosorbent assay. We also detected the presence of eotaxin protein immunohistochemically. RESULTS: On the one hand, urinary levels of eotaxin were significantly higher before the initiation of glucocorticoid administration in the patient with interstitial nephritis with marked infiltration of eosinophils. On the other hand, urinary eotaxin levels were not detected in any patients with nephrotic syndrome, interstitial nephritis without eosinophils, hypereosinophilic syndrome without renal involvement or other renal diseases. Serum eotaxin levels were not detected in any of the patients. Therefore, the detection of eotaxin in the urine was specific for renal interstitial eosinophilia. Moreover, endothelial cells, infiltrating mononuclear cells and renal epithelial cells in the tubulointerstitial lesions were immunostained with specific anti-eotaxin antibodies. Furthermore, the elevated urinary levels of eotaxin decreased dramatically during glucocorticoid-induced convalescence. HYPOTHESIS: We hypothesize that in situ expression of eotaxin may provide a new mechanism to explain the renal interstitial eosinophil infiltration. (+info)A case of eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma. (3/1319)
This report describes a patient with eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma. A 50-year-old man presented with a complaint of precordial pain. However, the only abnormal finding on examinatioin was eosinophilia (1617 eosinophils/microl). Three years later, the patient developed chronic eczema, and was diagnosed with erythroderma posteczematosa. One year later, a tumor was detected in the right auricule, and a diagnosis of Kimura's disease was made, based on the biopsy findings. The patient developed progressive dyspnea 6 months later and was found to have cardiomegaly and a depressed left ventricular ejection fraction (17%). A diagnosis of eosinophilic myocarditis was made based on the results of a right ventricular endomyocardial biopsy. The eosinophilic myocarditis and erythrodrema were treated with steroids with improvement of both the eosinophilia and left ventricular function. (+info)Differential chemokine expression in tissues involved by Hodgkin's disease: direct correlation of eotaxin expression and tissue eosinophilia. (4/1319)
Hodgkin's disease (HD) is a lymphoid malignancy characterized by infrequent malignant cells surrounded by abundant inflammatory cells. In this study, we examined the potential contribution of chemokines to inflammatory cell recruitment in different subtypes of HD. Chemokines are small proteins that are active as chemoattractants and regulators of cell activation. We found that HD tissues generally express higher levels of interferon-gamma-inducible protein-10 (IP-10), Mig, RANTES, macrophage inflammatory protein-1alpha (MIP-1alpha), and eotaxin, but not macrophage-derived chemotactic factor (MDC), than tissues from lymphoid hyperplasia (LH). Within HD subtypes, expression of IP-10 and Mig was highest in the mixed cellularity (MC) subtype, whereas expression of eotaxin and MDC was highest in the nodular sclerosis (NS) subtype. A significant direct correlation was detected between evidence of Epstein-Barr virus (EBV) infection in the neoplastic cells and levels of expression of IP-10, RANTES, and MIP-1alpha. Levels of eotaxin expression correlated directly with the extent of tissue eosinophilia. By immunohistochemistry, IP-10, Mig, and eotaxin proteins localized in the malignant Reed-Sternberg (RS) cells and their variants, and to some surrounding inflammatory cells. Eotaxin was also detected in fibroblasts and smooth muscle cells of vessels. These results provide evidence of high level chemokine expression in HD tissues and suggest that chemokines may play an important role in the recruitment of inflammatory cell infiltrates into tissues involved by HD. (+info)Treatment with interleukin-2 (IL-2) and interferon (IFN(alpha 2b)) after autologous bone marrow or peripheral blood stem cell transplantation in onco-hematological malignancies with a high risk of relapse. (5/1319)
Nine patients with onco-hematological malignancies with a poor prognosis due to high risk of relapse received immunotherapy with interleukin-2 (IL-2) and interferon (IFN(alpha 2b)) s.c. as maintenance therapy after receiving autologous bone marrow or peripheral blood stem cell transplantation (ABMT/PBSCT). All the patients were considered at very high risk of relapse. We attempted to assess the efficiency, toxicity and clinical effects of these cytokines in these patients. Five patients were treated with high-dose of IL-2 and the other four patients with escalating doses every month. Side-effects in the first group of patients consisted of fever, chills, weakness, nausea, anorexia, loss of weight and local dermatitis in the injection site. Toxicity on the WHO scale was grade II in three patients and grade IV in the other two patients. In the second group of patients, the same clinical signs of toxicity appeared, but these were grade I on the WHO scale in all patients. None of the patients had infections or died in relation to administration of IL-2. Four patients died of relapse or progression of their hematological malignancies. The other five patients are alive, one in chronic phase of CML and the other four patients are in complete remission of their malignancies. (+info)CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness. (6/1319)
Viral respiratory infections can cause bronchial hyperresponsiveness and exacerbate asthma. In mice, respiratory syncytial virus (RSV) infection results in airway hyperresponsiveness (AHR) and eosinophil influx into the airways. The immune cell requirements for these responses to RSV infection are not well defined. To delineate the role of CD8 T cells in the development of RSV-induced AHR and lung eosinophilia, we tested the ability of mice depleted of CD8 T cells to develop these symptoms of RSV infection. BALB/c mice were depleted of CD8 T cells using anti-CD8 Ab treatment before intranasal administration of infectious RSV. Six days postinfection, airway responsiveness to inhaled methacholine was assessed by barometric body plethysmography, and numbers of lung eosinophils and levels of IFN-gamma, IL-4, and IL-5 in bronchoalveolar lavage fluid were monitored. RSV infection resulted in airway eosinophilia and AHR in control mice, but not in CD8-depleted animals. Further, whereas RSV-infected mice secreted increased amounts of IL-5 into the airways as compared with noninfected controls, no IL-5 was detectable in both bronchoalveolar lavage fluid and culture supernatants from CD8-depleted animals. Treatment of CD8-depleted mice with IL-5 fully restored both lung eosinophilia and AHR. We conclude that CD8 T cells are essential for the influx of eosinophils into the lung and the development of AHR in response to RSV infection. (+info)Poverty and eosinophilia are risk factors for endomyocardial fibrosis (EMF) in Uganda. (7/1319)
OBJECTIVE: To determine the relative risks of socio-demographic, dietary, and environmental factors for endomyocardial fibrosis (EMF) in Uganda. METHOD: Unmatched case control study in Mulago Hospital, Kampala. Cases (n = 61) were sequential patients hospitalized with an echocardiographic diagnosis of EMF from June 1995 to March 1996. Controls (n = 120) were concurrent patients with other forms of heart disease (heart controls, n = 59) and subjects admitted for trauma or elective surgery (hospital controls, n = 61). All consenting subjects answered a structured questionnaire administered by trained interviewers. Complete blood counts, malaria films and stool examination for ova and parasites were performed. Questionnaires elicited information on home address, economic circumstances, variables concerned with environmental exposures and usual diet before becoming ill. RESULTS: After adjustment for age and sex, cases were significantly more likely than controls to have Rwanda/Burundi ethnic origins (P = 0.008). Compared with controls, cases had a lower level of education (P < 0.001 for heart controls and P = 0.07 for hospital controls), were more likely to be peasants (P < 0.001), and to come from Luwero or Mukono Districts (P = 0.003). After further adjustment for peasant occupation, cases were more likely than controls to walk barefoot (P = 0.015), consume cassava as their staple food (P < 0.001) and to lack fish or meat in dietary sauces (P = 0.02). Cases were more likely to exhibit absolute eosinophilia (P = 0.006). The effect of cassava diet was more marked in the younger age group, while the effect of eosinophilia was greater in adults. Socio-economic disadvantage is a risk for EMF. Absolute eosinophilia is a putative cause of EMF, a finding not explained by parasitism. CONCLUSION: Data indicate that relative poverty and environmental factors triggering eosinophilia appear to act in a geographically restricted region of Uganda in the aetiology of EMF. (+info)An adoptive transfer model of allergic lung inflammation in mice is mediated by CD4+CD62LlowCD25+ T cells. (8/1319)
Animal models of allergic lung inflammation have provided important insight into the cellular and biochemical factors involved in the pathogenesis of human asthma. Herein, we describe an adoptive transfer model of OVA-specific eosinophilic lung inflammation in the mouse that is used to characterize the cells involved in mediating the pulmonary inflammatory response. We report that freshly isolated spleen cells from OVA-sensitized mice are unable to prime naive recipient mice to respond to a subsequent OVA aerosol challenge. Subjecting the spleen cells to short term restimulation with Ag in vitro, however, renders the cells competent to transfer activity. The magnitude and the kinetics of the eosinophilic pulmonary inflammation in the adoptive transfer recipients are nearly identical with those generated by a more conventional active sensitization/challenge protocol, with the notable exception of differential production of plasma IgE in the two models. Extensive negative and positive selection of splenocyte subtypes indicates that the transfer of Ag-primed CD4+ T cells is both necessary and sufficient to establish full responsiveness in the recipient mice. Additional phenotypic characterization of the transfer-reactive CD4+ T cells indicates that they are found within the CD62LlowCD25+ subset and secrete high levels of IL-5 in response to Ag stimulation. Limiting dilution analysis-derived minimal frequency estimates indicate that approximately 1 in 8500 of the sensitized, cultured spleen cells produces IL-5 in response to OVA stimulation in vitro, suggesting that eosinophilic lung inflammation can be induced in naive mice by the transfer of <1200 Ag-specific CD4+ T cells. (+info)
Eosinophilic gastroenteritis synonyms, Eosinophilic gastroenteritis antonyms - FreeThesaurus.com
Peripheral eosinophilia in the diagnosis of chronic rhinosinusitis<...
Peripheral eosinophilia and its relation with CT scores in chronic rhinosinusitis
Causes of eosinophilic gastroenteritis - What You Need to Know
Eosinophilia - Mayo Clinic
Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9 | Respiratory Research | Full Text
Eosinophilia - Wikipedia
MRIMS Journal
Eosinophilic Gastroenteritis - NORD (National Organization for Rare Disorders)
Eosinophilic gastroenteritis in three ferrets. - Semantic Scholar
Eosinophilic Gastroenteritis in Dogs | Stomach Inflammation | Diarrhea in Dogs | petMD
Eosinophilic Gastroenteritis in Cats - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
Clinicopathologic Findings in Eosinophilic Gastroenteritis: A German Case Series | OMICS International
Pediatric Eosinophilic Gastroenteritis (EGE)
Marked peripheral eosinophilia due to prolonged administration of posaconazole | Microbiology Society
Tropical eosinophilia - Wikipedia
glossary:eosinophilia
T-cell lymphoblastic lymphoma with eosinophilia associated with subsequent myeloid malignancy<...
Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia - Full Text View - ClinicalTrials.gov
Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial | European Respiratory Society
Eosinophilic Disorders - Page 7 - BabyCenter
Eosinophilia | Denver Health
Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis
Role of IL-5 in IL-2-induced eosinophilia. In vivo and in vitro expression of IL-5 mRNA by IL-2 - Keio University
Rabbit polyclonal to Smac. | Evolution of NADPH Oxidase Inhibitors
EGE | Apfed
Eosinophilic Gastroenteritis with Ileus and Ascites
Eosinophilia in returning travellers and migrants from the tropics: UK recommendations for investigation and initial management...
Malignant lymphoma with eosinophilia of the gastrointestinal tract<...
Steroid naive eosinophilic asthma: anti-inflammatory effects of fluticasone and montelukast | Thorax
Home Remedies For Eosinophilia | Speedy Remedies
Eosinophilia in a patient with cyclical vomiting: a case report | Clinical and Molecular Allergy | Full Text
Pulmonary Eosinophilia: Background, Pathophysiology, Epidemiology
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PTU-168 Tomatoes Wearing Sunglasses Are Hard to Swallow - an Analysis of the Prevalence, Presenting Features & Investigation...
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Cytogenetics, FISH Panel for Eosinophilia | MLabs
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Myeloid Neoplasms W Eosinophilia FISH Probes
Blood test showed eosinophilia. Recommended tablet. What does this mean and why does it occur?
I Eosinophilia
Eosinophilia | Treatment of Eosinophilia
Eosinophilia Treatment In Ghaziabad - View Cost, Book Appointment Online | Practo
Evidence that 13-14 di-hydro, 15-keto prostaglandin D(2)-induced airway eosinophilia in guinea-pigs is independent of...
Most recent papers with the keyword Drug reaction eosinophilia and systemic symptoms | Read by QxMD
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Eosinophilia
"EOS eosinophilia, familial [Homo sapiens (human)] - Gene - NCBI". OMIM Entry - % 131400 - EOSINOPHILIA, FAMILIAL Klion AD, Law ... A parasitic infection of nearly any bodily tissue can cause eosinophilia.[citation needed] Diseases that feature eosinophilia ... Clinical manifestations and tissue destruction related to the eosinophilia in this disorder are uncommon: familial eosinophilia ... Congenital disorders Hyperimmunoglobulin E syndrome Omenn syndrome Familial eosinophilia Eosinophilia-myalgia syndrome " ...
Familial eosinophilia
... see clonal eosinophilia), clinical manifestations and tissue destruction related to the eosinophilia in familial eosinophilia ... Familial eosinophilia is a rare congenital disorder characterized by the presence of sustained elevations in blood eosinophil ... Individuals with familial eosinophilia exhibit hypereosinophilia presumably from birth (earliest documentation at 4 months of ... Curtis C, Ogbogu PU (2015). "Evaluation and Differential Diagnosis of Persistent Marked Eosinophilia". Immunology and Allergy ...
Tropical eosinophilia
The condition of marked eosinophilia with pulmonary involvement was first termed tropical pulmonary eosinophilia in 1950. The ... Udwaida F. (1975). "Tropical eosinophilia". In Herzog H (ed.). Pulmonary eosinophilia: progress in respiration research. Basel ... Tropical eosinophilia is considered a manifestation of a species of microfilaria. The filariasis is transmitted by a vector, ... Tropical (pulmonary) eosinophilia, or TPE, is characterized by coughing, asthmatic attacks, and an enlarged spleen, and is ...
Eosinophilia-myalgia syndrome
The presence of eosinophilia is a core feature of EMS, along with unusually severe myalgia (muscle pain). The initial, acute ... Eosinophilia-myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary ... "Rare Disease Database: Eosinophilia-Myalgia Syndrome". National Organization for Rare Disorders. NORD. Archived from the ... October 1990). "Eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Analysis of four patients and ...
Angiolymphoid hyperplasia with eosinophilia
... (also known as: "Epithelioid hemangioma," "Histiocytoid hemangioma," "Inflammatory ... a mimic of angiolymphoid hyperplasia with eosinophilia". Dermatology. 223 (4): 301-305. doi:10.1159/000335372. PMID 22269779. ...
Drug reaction with eosinophilia and systemic symptoms
Nam YH, Park MR, Nam HJ, Lee SK, Kim KH, Roh MS, Um SJ, Son CH (2015). "Drug reaction with eosinophilia and systemic symptoms ... Drug reaction with eosinophilia and systemic symptoms (DRESS), also termed drug-induced hypersensitivity syndrome (DIHS), is a ... Cho YT, Yang CW, Chu CY (2017). "Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, ... Chen, YC; Chiu, HC; Chu, CY (2010). "Drug reaction with eosinophilia and systemic symptoms: A retrospective study of 60 cases ...
Allergic inflammation
Rothenberg ME; Rothenberg, Marc E. (1998). "Eosinophilia". N. Engl. J. Med. 338 (22): 1592-600. doi:10.1056/NEJM199805283382206 ...
Löffler's syndrome
... is known as Loeffler endocarditis and can be caused by idiopathic eosinophilia or eosinophilia in response to parasitic ... Eosinophilia is the main feature of diagnostic criteria for Loffler's syndrome. Eosinophils are white blood cells that fight ... "Eosinophilia". Mayo Clinic. Retrieved 2018-12-05. "What Is an Eosinophil Count?". WebMD. Retrieved 2018-12-05. "Loeffler ... If the cause is unknown, it is specified and called "simple pulmonary eosinophilia". Cardiac damage caused by the damaging ...
Eosinophilic myocarditis
Clonal eosinophilia caused by mutations in genes that are highly susceptible to tyrosine kinase inhibitors such as PDGFRA, ... For example, an underlying malignant cause for the eosinophilia may be survival-limiting. In 1936, the famed Swiss physician ... The DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a severe immunological drug reaction. It differs ... Hypereosinophilia (i.e. blood eosinophil counts at or above 1,500 per microliter) or, less commonly, eosinophilia (counts above ...
Protriptyline
... eosinophilia. Gastrointestinal: Nausea and vomiting; anorexia; epigastric distress; diarrhea; peculiar taste; stomatitis; ...
Eosinophilic pneumonia
Asthma Parasitic pneumonia Pneumonia Bain GA, Flower CD (1996). "Pulmonary eosinophilia". European Journal of Radiology. 23 (1 ... Parasitic infections Tropical pulmonary eosinophilia Tuberculosis Fungal infection Sarcoidosis Drug reaction with eosinophilia ...
Eosinophilic granulomatosis with polyangiitis
"Eosinophilia Causes." Mayo Clinic, "Eosinophilia - Mayo Clinic". Mayo Clinic. Accessed 17 Nov. 2021. Rich et al. 2012, p. 701. ... tissue eosinophilia, and extravascular granuloma. As a result, they proposed that these cases were evident of a different ... Asthma Eosinophilia, i.e. eosinophil blood count greater than 500/microliter, or hypereosinophilia, i.e. eosinophil blood count ...
Spirocerca lupi
Eosinophilia is uncommon. Faecal evaluation is readily available and in some hands, especially those using the sugar flotation ...
Nephrogenic systemic fibrosis
... eosinophilia-myalgia syndrome; porphyria cutanea tarda, and other disorders. The nearly universal absence of facial skin ...
Tryptophan
There was a large outbreak of eosinophilia-myalgia syndrome (EMS) in the U.S. in 1989, with more than 1,500 cases reported to ... Back EE, Henning KJ, Kallenbach LR, Brix KA, Gunn RA, Melius JM (April 1993). "Risk factors for developing eosinophilia myalgia ... Kilbourne EM, Philen RM, Kamb ML, Falk H (October 1996). "Tryptophan produced by Showa Denko and epidemic eosinophilia-myalgia ... "COT Statement on Tryptophan and the Eosinophilia-Myalgia Syndrome" (PDF). UK Committee on Toxicity of Chemicals in Food, ...
FIP1L1
At least one case of FIP1L1-PDGFRA-induced disease presented as a myeloid sarcoma with eosinophilia has been reported. (i.e. ... The ~70% of patients with the FIP1L1-PDGFRA fusion gene (also termed the F/P fusion gene) and marked eosinophilia commonly ... However, lower levels of eosinophil counts and/or eosinophilia with a shorter history of duration are not a counter-indication ... This examination may be useful in excluding other malignant diseases associated with eosinophilia such as acute myeloid ...
PDGFRB
The disease is now classified by the World Health Organization as one form of clonal eosinophilia. It is critical that the ... Mutations in PDGFRB are mainly associated with the clonal eosinophilia class of malignancies. The PDGFRB gene is located on ... In all instances, these gene fusion diseases are considered types of clonal eosinophilia with recommended treatment regimens ... They commonly present with anemia, eosinophilia, monocytosis, and splenomegaly and have their disease classified as chronic ...
Gil Omenn
Omenn, Gilbert S. (19 August 1965). "Familial Reticuloendotheliosis with Eosinophilia". New England Journal of Medicine. 273 (8 ...
ETV6
Keung YK, Beaty M, Steward W, Jackle B, Pettnati M (October 2002). "Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34; ... Reiter A, Gotlib J (February 2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi:10.1182/blood-2016-10- ... "Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3". Blood ...
Trichostrongylus
Eosinophilia is frequently observed. Infections with a heavy worm burden can lead to anemia, cholecystitis, and emaciation. ... "Abdominal pain and eosinophilia in suburban goat keepers - trichostrongylosis". Medical Journal of Australia. 184 (9): 467-469 ...
Mansonella perstans
He had 3% eosinophilia. A visual acuity test showed a reduction of visual acuity to 4/10 for the left eye, while the right eye ... Eosinophilia, headache, fever, or abdominal pain may also be present. M. perstans may also present with a condition known as ... eosinophilia, and abdominal pain. The overall disability among populations in regions where filariae are endemic has been ...
Janus kinase 2
Reiter A, Gotlib J (2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi:10.1182/blood-2016-10-695973. ... particularly clonal eosinophilia forms of the disease. Mutations in JAK2 have been implicated in polycythemia vera, essential ...
Leukemia
ISBN 978-92-832-2411-2. Reiter A, Gotlib J (February 2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi ...
Adrenal insufficiency
Eosinophilia may also occur. Hyponatremia is a sign of secondary insufficiency. When functioning normally, the adrenal glands ... "Diagnostic complexities of eosinophilia". Archives of Pathology & Laboratory Medicine. 137 (2): 259-69. doi:10.5858/arpa.2011- ...
Gnathostoma hispidum
High eosinophilia is present. Surgical removal or treatment with albendazole or ivermectin is recommended. For additional ...
Hypereosinophilic syndrome
... and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or ... HES is a diagnosis of exclusion, after clonal eosinophilia (such as FIP1L1-PDGFRA-fusion induced hypereosinophelia and leukemia ... Reiter A, Gotlib J (2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi:10.1182/blood-2016-10-695973. ...
Strongyloidiasis
Absence of eosinophilia in an infection limited to the gastrointestinal tract may indicate poor prognosis. Eosinophilia is ... Eosinophilia of a gastrointestinal infection may fluctuate in response to larval output, or may be permanently lacking in some ... Hence lack of eosinophilia is not evidence of absence of infection. The combination of clinical suspicion, a positive antibody ... Eosinophilia is generally present. Strongyloidiasis can become chronic and then become completely asymptomatic.[citation needed ...
Mohammed Fazle Rabbee
Azad Khan, AK; Patra, RW; Banu, SA; Rabbee, MF (April 1970). "Spirometry in Tropical Pulmonary Eosinophilia". British Journal ... "Spirometry in Tropical Pulmonary Eosinophilia". On 15 December 1971, Rabbee was brutally killed when the Bangladesh Liberation ...
List of OMIM disorder codes
MPO Myeloproliferative disorder with eosinophilia; 131440; PDGFRB Myoclonic epilepsy, severe, of infancy; 607208; GABRG2 ...
Diethylcarbamazine
... tropical pulmonary eosinophilia, and loiasis. It may also be used for prevention of loiasis in those at high risk. While it has ... loiasis and tropical pulmonary eosinophilia. The WHO recommends prescribing diethylcarbamazine to people who are infected with ...
Eosinophilic Disorders | Eosinophilia | MedlinePlus
International Notes
Eosinophilia-Myalgia Syndrome -- Canada
Eosinophilia: Practice Essentials, Pathophysiology, Etiology
... the term eosinophilia is defined as an increase in peripheral blood eosinophilic leukocytes to more than 600 cells per ... Eosinophilia is a feature of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, a rare delayed ... encoded search term (Eosinophilia) and Eosinophilia What to Read Next on Medscape ... No racial predilection exists for eosinophilia, although the occurrence of eosinophilia-associated helminthic parasitic ...
Eosinophilia Guidelines: Guidelines Summary
... the term eosinophilia is defined as an increase in peripheral blood eosinophilic leukocytes to more than 600 cells per ... Treatment of clonal eosinophilia includes the following:. * Patients with clonal eosinophilia with FIP1L1-PDGFRA (including ... encoded search term (Eosinophilia) and Eosinophilia What to Read Next on Medscape ... Eosinophilia in patients infected with human immunodeficiency virus. J Infect Dis. 1996 Sep. 174(3):615-8. [QxMD MEDLINE Link] ...
EOSINOPHILIA IN ASTHMA | The BMJ
Eosinophilia | GreenMedInfo | Disease | Natural Medicine
Additional Keywords : anti-inflammatory, Asthma, Black Seed, Eosinophilia, Nigella sativa oil (NSO) ... Promising evaluation of homeopathic Blatta orientalis (Q) nasal gel formulation in milk aspiration induced eosinophilia.Dec 31 ... Antioxidant supplements ameliorate toluene diisocyanate exposure induced laryngo-tracheal eosinophilia.Oct 01, 2003. ...
Sputum eosinophilia predicts benefit from prednisone in smokers with chronic obstructive bronchitis
... Am J Respir Crit Care Med. ... Eight had sputum eosinophilia and similar clinical and physiologic characteristics to those of 10 patients without a finding of ... 3 mg/L to 5.4 mg/L (p , 0.001). These findings indicate that in smokers with severe airflow limitation, sputum eosinophilia ... Only in patients with sputum eosinophilia did prednisone, as compared with placebo, produce a statistically significant and ...
Eosinophilia - Renal and Urology News
Acquired blood eosinophilia (much more prevalent than familial eosinophilia) may be of primary etiology or secondary to a wide ... Secondary eosinophilia: In tropical areas, this is mostly due to parasitic infections, while in developed nations eosinophilia ... When the above testing is negative, the cause may be characterized as idiopathic eosinophilia (eosinophilia of undetermined ... Eosinophilia indicates elevated levels of eosinophils in the peripheral blood, usually related to an infectious, neoplastic, or ...
Angiolymphoid hyperplasia with eosinophilia
Angiolymhpoid hyperplasia with eosinophilia has been associated with antecedent trauma, T-cell proliferation, infection, and ... This report details a case of widespread angiolymphoid hyperplasia with eosinophilia that flared while the patient was pregnant ... Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vascular proliferation that presents as dome-shaped, light-pink- ... Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vascular proliferation that presents as dome-shaped, light-pink- ...
2014 ICD-9-CM Diagnosis Code 288.3 : Eosinophilia
Predictors of sputum eosinophilia in severe asthma - ePrints Soton
Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein | European Respiratory...
Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein. A Tedeschi, N Milazzo, ... Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein ... Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein ... Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein ...
Why does a 4-year-old w/ Eosinophilia get bloating in face?
Pneumotox » Drug » Mephenidate (Methylphenidate) » I.c - Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
Dissociation of eosinophilia and airway hyperresponsiveness; eosinophil-deficient mice exhibit normal airway responses in a...
Dissociation of eosinophilia and airway hyperresponsiveness; eosinophil-deficient mice exhibit normal airway responses in a ... Lack of airway hyperresponsiveness and airway eosinophilia in STAT6 deficient mice is overcome by IL-5. Journal of Allergy and ... The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5 ... Dissociation of airway hyperresponsiveness from immunoglobulin E and airway eosinophilia in a murine model of allergic asthma. ...
Increases in airway eosinophilia and a th1 cytokine during the chronic asymptomatic phase of asthma<...
Increases in airway eosinophilia and a th1 cytokine during the chronic asymptomatic phase of asthma. In: Respiratory Medicine. ... Increases in airway eosinophilia and a th1 cytokine during the chronic asymptomatic phase of asthma. / Kim, Chang Keun; Choi, ... Increases in airway eosinophilia and a th1 cytokine during the chronic asymptomatic phase of asthma. Respiratory Medicine. 2010 ... Kim, C. K., Choi, J., Callaway, Z., Iijima, K., Volcheck, G., & Kita, H. (2010). Increases in airway eosinophilia and a th1 ...
Pulmonary Eosinophilia | Profiles RNS
"Pulmonary Eosinophilia" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Pulmonary Eosinophilia" by people in UAMS Profiles by year, ... Below are the most recent publications written about "Pulmonary Eosinophilia" by people in Profiles over the past ten years. ... Below are MeSH descriptors whose meaning is more general than "Pulmonary Eosinophilia". ...
Helminth-related Eosinophilia in African Immigrants, Gran Canaria
Infection of Mice with Mycobacterium bovis-Bacillus Calmette-Guérin (BCG) Suppresses Allergen-induced Airway Eosinophilia |...
Reduction of Airway Eosinophilia Was Dependent upon the Dose of Mycobacteria Used and the Route of Infection.. In all ... Inhibition of airway eosinophilia was both dependent upon the dose and route of BCG infection. Mice were subjected to the OVA ... Inhibition of airway eosinophilia was both dependent upon the dose and route of BCG infection. Mice were subjected to the OVA ... 6,A). In fact, as could be predicted, the IFN-γR−/− mice, but not controls develop a slight lung eosinophilia after BCG ...
Eosinophilia: Practice Essentials, Pathophysiology, Etiology
... the term eosinophilia is defined as an increase in peripheral blood eosinophilic leukocytes to more than 600 cells per ... Eosinophilia is a feature of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, a rare delayed ... encoded search term (Eosinophilia) and Eosinophilia What to Read Next on Medscape ... No racial predilection exists for eosinophilia, although the occurrence of eosinophilia-associated helminthic parasitic ...
Eosinophilia and Fibrosis Are Markers of Poor Disease Prognosis in Patients With Eosinophilic Fasciitis | PracticeUpdate
DailyMed - MELOXICAM tablet
5.10 Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). Drug Reaction with Eosinophilia and Systemic Symptoms ( ... 5.10 Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) 5.11 Fetal Toxicity 5.12 Hematologic Toxicity 5.13 Masking ... Eosinophilia is often present. Because this disorder is variable in its presentation, other organ systems not noted here may be ... Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) : Discontinue meloxicam and evaluate clinically (5.10) ...
IMSEAR at SEARO: Angiolymphoid hyperplasia with eosinophilia.
Eosinophilia-Myalgia Syndrome Workup: Laboratory Studies, Imaging Studies, Other Tests
... notified of 3 patients with an unexplained acute illness characterized by intense myalgias and peripheral blood eosinophilia. ... encoded search term (Eosinophilia-Myalgia Syndrome) and Eosinophilia-Myalgia Syndrome What to Read Next on Medscape ... Eosinophilia-Myalgia Syndrome Workup. Updated: Jan 12, 2021 * Author: William E Monaco, MD; Chief Editor: Herbert S Diamond, MD ... The eosinophilia-myalgia syndrome: the Los Alamos Conference. J Rheumatol. 1991 Jun. 18(6):867-73. [QxMD MEDLINE Link]. ...
Cardiac and pulmonary disease with eosinophilia<...
Wolff, S. M., & Fallon, J. T. (1980). Cardiac and pulmonary disease with eosinophilia. New England Journal of Medicine, 302(19 ... Wolff, S. M. ; Fallon, J. T. / Cardiac and pulmonary disease with eosinophilia. In: New England Journal of Medicine. 1980 ; Vol ... Wolff, SM & Fallon, JT 1980, Cardiac and pulmonary disease with eosinophilia, New England Journal of Medicine, vol. 302, no. ... Cardiac and pulmonary disease with eosinophilia. New England Journal of Medicine. 1980;302(19):1077-1083. ...
Figure 2 - Helminth-related Eosinophilia in African Immigrants, Gran Canaria - Volume 12, Number 10-October 2006 - Emerging...
Drug-Induced Pulmonary Eosinophilia - MD Nexus
Drug Rash with Eosinophilia and Systemic Symptoms (DRESS Syndrome) (see Drug Rash with Eosinophilia and Systemic Symptoms). ... CBC: eosinophilia*Nitrofurantoin acute-type syndrome usually has the highest degree of eosinophilia (as compared to subacute ... Drug-Induced Pulmonary Eosinophilia. Etiology. Anti-Androgenic Agents. *Bicalutamide (Casodex) (see Bicalutamide) ...
Angiolymphoid Hyperplasia with Eosinophilia | Profiles RNS
"Angiolymphoid Hyperplasia with Eosinophilia" is a descriptor in the National Library of Medicines controlled vocabulary ... This graph shows the total number of publications written about "Angiolymphoid Hyperplasia with Eosinophilia" by people in this ... Below are the most recent publications written about "Angiolymphoid Hyperplasia with Eosinophilia" by people in Profiles. ... Congenital Blaschkoid Angiolymphoid Hyperplasia With Eosinophilia of the Anogenital Region. Am J Dermatopathol. 2016 Apr; 38(4 ...
Pulmonary eosinophiliaHyperplasia with eosinophiliaEosinophil countPeripheral eosinophiliaIdiopathicLymphoid neoplasms with eosinophiliaEosinophilsMolecular or cytogenetic abnormalitySevereDiseasesSputum eosinophiliaClonal eosinophiliaPersistent eosinophiliaSyndromeSymptomsInfectionNeoplasmsNasalSystemicInfectionsAllergicDisordersLeukocytosisPDGFRBDrug-inducedASTHMAFeverDiagnosisBloodPatients2016ReactiveEdemaReactionsNeutropeniaIncreases
Pulmonary eosinophilia6
- Pulmonary Eosinophilia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
- This graph shows the total number of publications written about "Pulmonary Eosinophilia" by people in UAMS Profiles by year, and whether "Pulmonary Eosinophilia" was a major or minor topic of these publications. (uams.edu)
- Below are the most recent publications written about "Pulmonary Eosinophilia" by people in Profiles over the past ten years. (uams.edu)
- Tropical Pulmonary Eosinophilia (TPE) is usually a severe form of allergic asthma caused by the host inflammatory response to filarial helminths in the lung microvasculature and is characterized by pulmonary eosinophilia increased filarial-specific IgG and IgE antibodies and airway hyperresponsiveness. (conferencedequebec.org)
- Fluticasone propionate and pentamidine isethionate reduce airway hyperractivity, pulmonary eosinophilia and pulmonary dendritic cell response in a guinea pig model of asthma. (cdc.gov)
- Problems considered include the factors influencing the pathogenesis of tropical pulmonary eosinophilia and of renal lesions, the mechanisms involved in the parasite-specific hyporesponsiveness observed in many patients, and possible explanations for the distinctly different clinical and pathological responses seen in residents of endemic areas and in migrants to those areas. (who.int)
Hyperplasia with eosinophilia16
- Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vascular proliferation that presents as dome-shaped, light-pink-to-red-brown papules or subcutaneous masses that lack distinguishing surface changes. (cdlib.org)
- Angiolymhpoid hyperplasia with eosinophilia has been associated with antecedent trauma, T-cell proliferation, infection, and hormone imbalance. (cdlib.org)
- This report details a case of widespread angiolymphoid hyperplasia with eosinophilia that flared while the patient was pregnant. (cdlib.org)
- IMSEAR at SEARO: Angiolymphoid hyperplasia with eosinophilia. (who.int)
- Angiolymphoid Hyperplasia with Eosinophilia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (musc.edu)
- Below are the most recent publications written about "Angiolymphoid Hyperplasia with Eosinophilia" by people in Profiles. (musc.edu)
- Congenital Blaschkoid Angiolymphoid Hyperplasia With Eosinophilia of the Anogenital Region. (musc.edu)
- Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. (qxmd.com)
- Angiolymphoid hyperplasia with eosinophilia successfully treated with a long-pulsed tunable dye laser. (qxmd.com)
- Rapid remission of severe pruritus from angiolymphoid hyperplasia with eosinophilia by pulsed dye laser therapy. (qxmd.com)
- A case of angiolymphoid hyperplasia with eosinophilia (ALHE) of the upper lip. (qxmd.com)
- Angiolymphoid hyperplasia with eosinophilia on the palm. (qxmd.com)
- Spontaneous regression of a rare tumour in a child: angiolymphoid hyperplasia with eosinophilia of the hand: case report and review of the literature. (qxmd.com)
- Angiolymphoid hyperplasia with eosinophilia of the lacrimal gland: a case report. (qxmd.com)
- Angiolymphoid hyperplasia with eosinophilia (or eosinophils ) is also known as epithelioid or histiocytoid haemangioma (See also Epithelioid haemangioma pathology ). (dermnetnz.org)
- Kimura disease - Can closely resemble angiolymphoid hyperplasia with eosinophilia. (dermnetnz.org)
Eosinophil count3
- Patients with an eosinophil count of at least 1.5 × 10 9 /L with no obvious cause should be investigated for a possible hematological neoplasm with clonal eosinophilia, initially by peripheral blood analysis for FIP1L1-PDGFRA by fluorescence in situ hybridization (FISH) or nested reverse transcription polymerase chain reaction (RT-PCR) (Grade 1C). (medscape.com)
- Laboratory findings revealed eosinophilia (blood eosinophil count of 33%), white blood cell (WBC) count 11 500/mm3 and erythrocyte sedimentation rate (ESR) of 32 mm/h. (who.int)
- In laboratory tests, blood eosinophilia (eosinophil count of 30%), WBC 22 000/mm3 and ESR 45 mm/h were found. (who.int)
Peripheral eosinophilia3
- An increase in tissue eosinophilia may be seen with or without concurrent peripheral eosinophilia. (medscape.com)
- Bhattacharyya, N & Fried, MP 2001, ' Peripheral eosinophilia in the diagnosis of chronic rhinosinusitis ', American Journal of Otolaryngology - Head and Neck Medicine and Surgery , vol. 22, no. 2, pp. 116-120. (elsevier.com)
- In lab findings, there is almost always a marked peripheral eosinophilia and often, anemia and a hypergammaglobulinemia. (cdc.gov)
Idiopathic3
- Primary eosinophilia is not a reactive phenomenon and can be described as either clonal or idiopathic in nature. (medscape.com)
- If reactive causes are ruled out and no underlying clonal origin is proven, the eosinophilia is described as idiopathic. (medscape.com)
- In 2012, a panel of experts published recommendations on terminology of eosinophilia and introduced the term "hypereosinophilia of undetermined significance" in lieu of "idiopathic hypereosinophilia" (similar for idiopathic hypereosinophilic syndrome). (renalandurologynews.com)
Lymphoid neoplasms with eosinophilia1
- Other World Health Organization classification: In 2008, WHO added two new categories to classify myeloid and lymphoid neoplasms with eosinophilia. (renalandurologynews.com)
Eosinophils3
- In this article, the term eosinophilia is defined as an increase in peripheral blood eosinophils to more than 600 cells per microliter (μL) of blood. (medscape.com)
- Eosinophilia indicates elevated levels of eosinophils in the peripheral blood, usually related to an infectious, neoplastic, or allergic process. (renalandurologynews.com)
- Often, high numbers of eosinophils may be present in other body fluids or tissues, but the term typically refers to peripheral blood eosinophilia. (renalandurologynews.com)
Molecular or cytogenetic abnormality2
- If an underlying molecular or cytogenetic abnormality can be identified, the eosinophilia can be designated as a clonal disorder. (medscape.com)
- Patients with acute myeloid leukemia (AML) with clonal eosinophilia and no molecular or cytogenetic abnormality suggesting likely response to a tyrosine kinase inhibitor should be offered standard acute myeloid leukemia induction therapy (Grade 1A). (medscape.com)
Severe5
- Patients requiring emergency treatment for severe or life-threatening eosinophilia should receive high-dose corticosteroids (Grade 1B). (medscape.com)
- These findings indicate that in smokers with severe airflow limitation, sputum eosinophilia predicts a beneficial effect of prednisone treatment. (nih.gov)
- Eosinophilia-myalgia syndrome (EMS) was first recognized in 1989 in New Mexico in 3 patients who had an illness with a unique array of symptoms, including peripheral blood eosinophilia and severe myalgias. (medscape.com)
- Eosinophilia can be present as well as diarrhea that can be severe. (parasitologyworld.com)
- So imatinib which was originally investigated and approved for CML also works in some patients with severe eosinophilia, patients with GIST (one type of gastrointestinal tumor) and others. (shyamhemoncclinic.com)
Diseases2
- Also see the Medscape Drugs & Diseases article Eosinophilia-Myalgia Syndrome . (medscape.com)
- Based on these findings pharmacologic GRB2 inhibitors may have the potential to dampen tissue eosinophilia in various eosinophil -associated diseases . (bvsalud.org)
Sputum eosinophilia2
- Eight had sputum eosinophilia and similar clinical and physiologic characteristics to those of 10 patients without a finding of sputum eosinophilia. (nih.gov)
- Only in patients with sputum eosinophilia did prednisone, as compared with placebo, produce a statistically significant and clinically important mean effect on effort dyspnea of 0.8 (95% confidence interval [CI]: 0.3 to 1.2), p = 0.008, and in quality of life of 1.96 (95% CI: 0.5 to 3.3), p = 0.01, associated with a small improvement in FEV1 of 0.11 L (95% CI: - 0.04 to 0.23 L), p = 0.05. (nih.gov)
Clonal eosinophilia3
- Patients with clonal eosinophilia with FIP1L1-PDGFRA (including patients presenting with acute leukemia), should be treated with low-dose imatinib (Grade 1B). (medscape.com)
- Patients with clonal eosinophilia with PDGFRB rearrangement or ETV6-ABL1 fusion should receive standard-dose imatinib (Grade 1B). (medscape.com)
- Some patients with FIP1L1-PDGFRa-positive clonal eosinophilia were previously diagnosed with HES before the mutation was discovered. (renalandurologynews.com)
Persistent eosinophilia1
- Patients with systemic symptoms and those with persistent eosinophilia (at least 1.5 × 10 9 /L), irrespective of suspected organ damage, should be considered for additional testing for an underlying cause. (medscape.com)
Syndrome10
- As of May 14, 1990, 10 confirmed cases of eosinophilia-myalgia syndrome (EMS) in Canada have been reported to the Laboratory Centre for Disease Control (LCDC), and other possible cases are under investigation. (cdc.gov)
- Eosinophilia-myalgia syndrome--New Mexico. (cdc.gov)
- Given the myriad different ways eosinophilia-myalgia syndrome (EMS) can present, the initial workup should be directed at identifying other possible causes. (medscape.com)
- Rigorous new approach to constructing a gold standard for validating new diagnostic criteria, as exemplified by the eosinophilia-myalgia syndrome. (medscape.com)
- Criteria for the definition of the eosinophilia-myalgia syndrome. (medscape.com)
- Pathophysiology of the eosinophilia-myalgia syndrome. (medscape.com)
- Eosinophilia-myalgia syndrome (EMS) is an illness characterized by pruritus, cutaneous lesions, edema, sclerodermoid changes, and joint pain, in addition to dramatic myalgia and eosinophilia. (medscape.com)
- Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) / Drug-induced Hypersensitivity Syndrome (DIHS): a review of current concepts. (ikpresse.com)
- Carbamazepine-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: report of four cases and brief review. (ikpresse.com)
- Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Induced by Levetiracetam in a Pediatric Patient. (ikpresse.com)
Symptoms2
Infection4
- We have investigated this issue by combining an intranasal Mycobacterium bovis -Bacillus Calmette-Guérin (BCG) infection with a murine model of allergen, (ovalbumin [OVA]) induced airway eosinophilia. (rupress.org)
- BCG infection either 4 or 12 wk before allergen airway challenge resulted in a 90-95 and 60-70% reduction in eosinophilia within the lungs, respectively, compared to uninfected controls. (rupress.org)
- Notably, Strongyloides stercoralis , which is is endemic in tropical and subtropical climates, can propagate itself internally and cause eosinophilia several decades after initial infection. (medscape.com)
- Eosinophilia occurs in response to parasitic infection and exposure to allergens. (ispub.com)
Neoplasms1
- Myeloid or lymphoid neoplasms associated with eosinophilia and genetic abnormalities PDGFRa, PDGFRb, FIP1L1 (i.e., genes for tyrosine kinase platelet-derived growth factor receptors or fibroblast growth factor receptor rearrangements). (renalandurologynews.com)
Nasal2
- Promising evaluation of homeopathic Blatta orientalis (Q) nasal gel formulation in milk aspiration induced eosinophilia. (greenmedinfo.com)
- It has been demonstrated that platelet-activating factor (PAF)-acether can induce nasal neutrophilia and eosinophilia, with a different degree of responsiveness in atopic and in nonatopic subjects. (ersjournals.com)
Systemic1
- EL Omairi N, Abourazzak S, Chaouki S, Atmani S, Hida M. Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) induced by carbamazepine: a case report and literature review. (ikpresse.com)
Infections1
- Secondary eosinophilia: In tropical areas, this is mostly due to parasitic infections, while in developed nations eosinophilia is mostly the result of non-infectious causes. (renalandurologynews.com)
Allergic2
- Murine eosinophil development and allergic lung eosinophilia are largely dependent on the signaling adaptor GRB2. (bvsalud.org)
- Furthermore, Aspergillus fumigatus -induced allergic lung eosinophilia was significantly reduced in mice with induced genetic deletion of Grb2. (bvsalud.org)
Disorders1
- Acquired blood eosinophilia (much more prevalent than familial eosinophilia) may be of primary etiology or secondary to a wide variety of disorders. (renalandurologynews.com)
Leukocytosis1
- We also sought to assess whether the absence of leukocytosis and eosinophilia could allow a diagnosis of CSS to be rejected. (who.int)
PDGFRB1
- Primary eosinophilia: Occurs mostly in males in patients with myeloproliferative variants or PDGFRA/PDGFRB gene aberrations. (renalandurologynews.com)
Drug-induced1
- Clinical suspicion should extend to agents in long-term use, as drug-induced eosinophilia may develop months and even years after initiation of therapy. (medscape.com)
ASTHMA1
- GM-CSF, instead of IL-5, and chemokines may coordinate airway eosinophilia during the chronic asymptomatic phase of asthma. (elsevier.com)
Fever1
- He developed multiple maculopapular rashes, facial puffiness, fever, lymphadenopathy with leucocytosis and eosinophilia about four weeks after commencing carbamazepine. (ikpresse.com)
Diagnosis2
- A guideline on the diagnosis and treatment of eosinophilia from the British Committee on Standards in Haematology advises that the underlying cause of eosinophilia should be sought and possible eosinophil-associated end-organ damage should be evaluated (Grade 1B). (medscape.com)
- 3 4 However, given the evidence of eosinophilia with elevated IgE and perivascular eosinophilic infiltration in granulomatous inflammation of dermis on biopsy, multidisciplinary discussion led to the diagnosis of EGPA or a rare entity of eosinophilic vasculitis with thrombotic complication. (bmj.com)
Blood7
- Usually parasites that are isolated to the intestinal lumen or are intact cysts (Echinococcus) do not cause blood eosinophilia unless there is tissue invasion or cyst dysruption. (renalandurologynews.com)
- Laboratory blood tests demonstrated an eosinophilia (21 %, 1743 cells/µL) with marked elevation of IgE (4200 mg/dL) as well as inflammatory reaction such as erythrocyte sedimentation rate 84 mm/h and C-reactive protein 0.85 mg/dL. (bmj.com)
- Purpose: To determine the relationship between peripheral blood eosinophilia and chronic rhinosinusitis. (elsevier.com)
- Exhaled nitric oxide and blood eosinophilia: independent markers of preventable risk. (ox.ac.uk)
- Extensive blood stream eosinophilia american initial slots games online free of cost is typical. (hassanmushtaq.com)
- Survival correlated significantly with the development of intense vaccine injection site reactions, and with blood eosinophilia after the first series of vaccinations, suggesting that prolonged survival was a consequence of DC vaccination. (jci.org)
- Long-term survival in advanced melanoma patients undergoing DC vaccination is similar to ipilimumab-treated patients and occurs upon induction of tumor-specific T cells, blood eosinophilia, and strong vaccine injection site reactions occurring after the initial vaccinations. (jci.org)
Patients5
- Given the broad spectrum of conditions linked to eosinophilia, this article emphasizes the diagnostic considerations that clinicians may want to focus on in patients with eosinophilia. (medscape.com)
- Patients who are otherwise well with mild to moderate eosinophilia between 0.5 and 1.5 × 10 9 /L may not require further testing. (medscape.com)
- In patients with end-organ damage, the frequency of further serial evaluations of organ function should be determined by the severity and extent of organ compromise and/or by worsening of the eosinophilia (Grade 2C). (medscape.com)
- Jack Cush, MD, discusses considerations when #eosinophilia is observed in patients with #rheumatoidarthritis. (thedoctorschannel.com)
- Somatic STAT5B N642H gain-of-function mutation in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea in two young patients. (cusabio.com)
20161
- Eosinophilia is a well- by Angiostrongylus cantonensis , France, 2016. (cdc.gov)
Reactive1
- Specific causes of reactive eosinophilia, based on clinical suspicion, should be confirmed or excluded at an early stage by appropriate testing (Grade 1C). (medscape.com)
Edema1
- Facial edema, eosinophilia, and elevated liver-enzyme levels developed later. (friendsoftheugagarden.org)
Reactions1
- Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions. (nature.com)
Neutropenia1
- PubMed is a searchable database of medical literature and lists journal articles that discuss Neutropenia lethal congenital with eosinophilia. (rarepsychiatrynews.com)
Increases1
- We discuss the controversial concept of the association whether eosinophilia increases the risk profile or does it mitigate the risk of the deadly disease, diabetes. (ijcmph.com)