Enterococcus faecalis
Enterococcus
Enterococcus faecium
Gram-Positive Bacterial Infections
Vancomycin Resistance
Carbon-Oxygen Ligases
Vancomycin
Microbial Sensitivity Tests
Drug Resistance, Microbial
Ampicillin Resistance
Conjugation, Genetic
A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.
Bacteriocins
Teicoplanin
Gentamicins
Virginiamycin
A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. It consists of 2 major components, VIRGINIAMYCIN FACTOR M1 and virginiamycin Factor S1. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
Oxazolidinones
Acetamides
Gram-Positive Cocci
Drug Resistance, Bacterial
Streptococcus
Electrophoresis, Gel, Pulsed-Field
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Endocarditis, Bacterial
Glycopeptides
Bacterial Typing Techniques
Pheromones
Lactococcus
Sequence Analysis, DNA
Plasmids
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Streptococcaceae
DNA Transposable Elements
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Ampicillin
Feces
Cheese
Colony Count, Microbial
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
Biofilms
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
Anti-Infective Agents
Gram-Negative Bacteria
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Bacteremia
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
Gene Expression Regulation, Bacterial
Streptogramins
RNA, Ribosomal, 16S
Aminoglycosides
Base Sequence
Staphylococcus aureus
Bacterial Adhesion
Peptide Synthases
Amino Acid Sequence
Tetracycline Resistance
Food Microbiology
Streptogramin A
Muramoylpentapeptide Carboxypeptidase
Root Canal Irrigants
Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.
Drug Resistance, Multiple, Bacterial
Dental Pulp Cavity
Virulence Factors
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
Penicillin-Binding Proteins
Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.
Lactobacillus
Gelatinases
Peptidyl Transferases
DNA, Ribosomal
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Serine-Type D-Ala-D-Ala Carboxypeptidase
Virulence
Sex Attractants
Microbial Viability
Urinary Tract Infections
Penicillins
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
RNA, Bacterial
Gene Transfer, Horizontal
The naturally occurring transmission of genetic information between organisms, related or unrelated, circumventing parent-to-offspring transmission. Horizontal gene transfer may occur via a variety of naturally occurring processes such as GENETIC CONJUGATION; GENETIC TRANSDUCTION; and TRANSFECTION. It may result in a change of the recipient organism's genetic composition (TRANSFORMATION, GENETIC).
Staphylococcus
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
Multilocus Sequence Typing
Multigene Family
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Sodium Hypochlorite
Erythromycin
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Operon
Probiotics
Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)
Nucleic Acid Hybridization
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Dental Pulp Diseases
Poultry
Minocycline
Gastrointestinal Tract
DNA Fingerprinting
A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying which combination of allelic variations occur in the individual at a statistically relevant number of different loci. In forensic studies, RESTRICTION FRAGMENT LENGTH POLYMORPHISM of multiple, highly polymorphic VNTR LOCI or MICROSATELLITE REPEAT loci are analyzed. The number of loci used for the profile depends on the ALLELE FREQUENCY in the population.
Antibiosis
Peritonitis
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
Disk Diffusion Antimicrobial Tests
Listeria
Streptomycin
Bacitracin
A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)
Phenotype
Mutagenesis, Insertional
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Chlorhexidine
Pulpitis
Cephalosporins
Chromosomes, Bacterial
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Chickens
Anti-Infective Agents, Local
Tyrosine Decarboxylase
RNA, Ribosomal, 23S
Periapical Periodontitis
Calcium Hydroxide
Molecular Epidemiology
Uridine Diphosphate N-Acetylmuramic Acid
Cloning, Molecular
Fermentation
Enterobacteriaceae
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
Bacteriolysis
Lactococcus lactis
Lactobacillaceae
Agar
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
Mutation
N-Acetylmuramoyl-L-alanine Amidase
Drug Therapy, Combination
Water Microbiology
Acetoin
Tylosin
Genotype
Serum Bactericidal Test
Method of measuring the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy. It is used to monitor the therapy in BACTERIAL ENDOCARDITIS; OSTEOMYELITIS and other serious bacterial infections. As commonly performed, the test is a variation of the broth dilution test. This test needs to be distinguished from testing of the naturally occurring BLOOD BACTERICIDAL ACTIVITY.
Adhesins, Bacterial
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.
Lincosamides
A family of LINCOMYCIN-related glycosides that contain a pyrrolidine ring linked via an amide-bond to a pyranose moiety. Individual members of this family are defined by the arrangement of specific constituent groups on the lyncomycin molecule. Many lincosamides are ANTIBIOTICS produced by a variety STREPTOMYCES species.
Genes, rRNA
Infection Control
Sequence Homology, Amino Acid
Quinolones
Cell Wall
Open Reading Frames
Endocarditis
Cluster Analysis
A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.
Evaluation Studies as Topic
Endophthalmitis
Potassium-Hydrogen Antiporters
Imipenem
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Chromogenic Compounds
Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).
Root Canal Filling Materials
Aminoacyltransferases
Nisin
Gram-Negative Bacterial Infections
Intestines
Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci. (1/1212)
BACKGROUND: High-level gentamicin resistance in enterococci and staphylococci is conferred by AAC(6')-APH(2"), an enzyme with 6'-N-acetyltransferase and 2"-O-phosphotransferase activities. The presence of this enzyme in pathogenic gram-positive bacteria prevents the successful use of gentamicin C and most other aminoglycosides as therapeutic agents. RESULTS: In an effort to understand the mechanism of aminoglycoside modification, we expressed AAC(6')-APH(2") in Bacillus subtilis. The purified enzyme is monomeric with a molecular mass of 57 kDa and displays both the expected aminoglycoside N-acetyltransferase and O-phosphotransferase activities. Structure-function analysis with various aminoglycosides substrates reveals an enzyme with broad specificity in both enzymatic activities, accounting for AAC(6')-APH(2")'s dramatic negative impact on clinical aminoglycoside therapy. Both lividomycin A and paromomycin, aminoglycosides lacking a 6'-amino group, were acetylated by AAC(6')-APH(2"). The infrared spectrum of the product of paromomycin acetylation yielded a signal consistent with O-acetylation. Mass spectral and nuclear magnetic resonance analysis of the products of neomycin phosphorylation indicated that phosphoryl transfer occurred primarily at the 3'-OH of the 6-aminohexose ring A, and that some diphosphorylated material was also present with phosphates at the 3'-OH and the 3"'-OH of ring D, both unprecedented observations for this enzyme. Furthermore, the phosphorylation site of lividomycin A was determined to be the 5"-OH of the pentose ring C. CONCLUSIONS: The bifunctional AAC(6')-APH(2") has the capacity to inactivate virtually all clinically important aminoglycosides through N- and O-acetylation and phosphorylation of hydroxyl groups. The extremely broad substrate specificity of this enzyme will impact on future development of aminoglycosides and presents a significant challenge for antibiotic design. (+info)Ciprofloxacin decreases the rate of ethanol elimination in humans. (2/1212)
BACKGROUND: Extrahepatic ethanol metabolism is postulated to take place via microbial oxidation in the colon, mediated by aerobic and facultative anaerobic bacteria. AIMS: To evaluate the role of microbial ethanol oxidation in the total elimination rate of ethanol in humans by reducing gut flora with ciprofloxacin. METHODS: Ethanol was administered intravenously at the beginning and end of a one week period to eight male volunteers. Between ethanol doses volunteers received 750 mg ciprofloxacin twice daily. RESULTS: A highly significant (p=0.001) reduction in the ethanol elimination rate (EER) was detected after ciprofloxacin medication. Mean (SEM) EER was 107.0 (5.3) and 96.9 (4.8) mg/kg/h before and after ciprofloxacin, respectively. Faecal Enterobacteriaceae and Enterococcus sp. were totally absent after medication, and faecal acetaldehyde production capacity was significantly (p<0.05) decreased from 0.91 (0.15) to 0.39 (0.08) nmol/min/mg protein. Mean faecal alcohol dehydrogenase (ADH) activity was significantly (p<0. 05) decreased after medication, but ciprofloxacin did not inhibit human hepatic ADH activity in vitro. CONCLUSIONS: Ciprofloxacin treatment decreased the ethanol elimination rate by 9.4%, with a concomitant decrease in intestinal aerobic and facultative anaerobic bacteria, faecal ADH activity, and acetaldehyde production. As ciprofloxacin has no effect on liver blood flow, hepatic ADH activity, or cytochrome CYP2E1 activity, these effects are probably caused by the reduction in intestinal flora. (+info)Diperamycin, a new antimicrobial antibiotic produced by Streptomyces griseoaurantiacus MK393-AF2. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. (3/1212)
Antibacterial antibiotics, diperamycin (1) was produced in the culture broth of Streptomyces griseoaurantiacus MK393-AF2. Various spectroscopic analyses of 1 suggested that 1 belonged to a member of cyclic hexadepsipeptide antibiotic. Antibiotic 1 had potent inhibitory activity against various Gram-positive bacteria including Enterococcus seriolicida and methicillin-resistant Staphylococcus aureus. (+info)Molecular diversity and evolutionary relationships of Tn1546-like elements in enterococci from humans and animals. (4/1212)
We report on a detailed study on the molecular diversity and evolutionary relationships of Tn1546-like elements in vancomycin-resistant enterococci (VRE) from humans and animals. Restriction fragment length polymorphism (RFLP) analysis of the VanA transposon of 97 VRE revealed seven different Tn1546 types. Subsequent sequencing of the complete VanA transposons of 13 VRE isolates representing the seven RFLP types followed by sequencing of the identified polymorphic regions in 84 other VanA transposons resulted in the identification of 22 different Tn1546 derivatives. Differences between the Tn1546 types included point mutations in orf1, vanS, vanA, vanX, and vanY. Moreover, insertions of an IS1216V-IS3-like element in orf1, of IS1251 in the vanS-vanH intergenic region, and of IS1216V in the vanX-vanY intergenic region were found. The presence of insertion sequence elements was often associated with deletions in Tn1546. Identical Tn1546 types were found among isolates from humans and farm animals in The Netherlands, suggesting the sharing of a common vancomycin resistance gene pool. Application of the genetic analysis of Tn1546 to VRE isolates causing infections in Hospitals in Oxford, United Kingdom, and Chicago, Ill., suggested the possibility of the horizontal transmission of the vancomycin resistance transposon. The genetic diversity in Tn1546 combined with epidemiological data suggest that the DNA polymorphism among Tn1546 variants can successfully be exploited for the tracing of the routes of transmission of vancomycin resistance genes. (+info)Transmission dynamics of epidemic methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in England and Wales. (5/1212)
A simple epidemiological framework for the analysis of the transmission dynamics of hospital outbreaks of epidemic methicillin-resistant Staphylococcus aureus (EMRSA) and vancomycin-resistant enterococci (VRE) in hospitals in England and Wales is presented. Epidemic strains EMRSA-15 and EMRSA-16 are becoming endemic in hospitals in the United Kingdom, and theory predicts that EMRSA-15 and EMRSA-16 will reach respective endemic levels of 158 (95% confidence interval [CI], 143-173) and 116 (95% CI, 109-123) affected hospitals with stochastic fluctuations of up to 30 hospitals in each case. An epidemic of VRE is still at an early stage, and the incidence of hospitals newly affected by VRE is growing exponentially at a rate r=0.51/year (95% CI, 0.48-0.54). The likely impact of introducing surveillance policies if action is taken sufficiently early is estimated. Finally, the role of heterogeneity in hospital size is considered: "Super-spreader hospitals" may increase transmission by 40%-132% above the expected mean. (+info)The Enterococcus hirae copper chaperone CopZ delivers copper(I) to the CopY repressor. (6/1212)
Expression of the cop operon which effects copper homeostasis in Enterococcus hirae is controlled by the copper responsive repressor CopY. Purified Zn(II)CopY binds to a synthetic cop promoter fragment in vitro. Here we show that the 8 kDa protein CopZ acts as a copper chaperone by specifically delivering copper(I) to Zn(II)CopY and releasing CopY from the DNA. As shown by gel filtration and luminescence spectroscopy, two copper(I) are thereby quantitatively transferred from Cu(I)CopZ to Zn(II)CopY, with displacement of the zinc(II) and transfer of copper from a non-luminescent, exposed, binding site in CopZ to a luminescent, solvent shielded, binding site in CopY. (+info)Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY. (7/1212)
BACKGROUND: Vancomycin-resistant enterococci are pathogenic bacteria that attenuate antibiotic sensitivity by producing peptidoglycan precursors that terminate in D-Ala-D-lactate rather than D-Ala-D-Ala. A key enzyme in effecting antibiotic resistance is the metallodipeptidase VanX, which reduces the cellular pool of the D-Ala-D-Ala dipeptide. RESULTS: We constructed eleven mutants, using the recently determined VanX structure as a basis, to investigate residue function. Mutating Asp142 or Ser114 showed a large effect principally on KM, consistent with roles in recognition of the D-Ala-D-Ala termini. The drastic reduction or absence of activity in the Arg71 mutants correlates with a role in the stabilization of an anionic tetrahedral transition state. Three residues of the Escherichia coli D-Ala-D-Ala ligase (Ddl), Glu15, Ser 281 and Arg255, are similarly conserved and have equivalent functions with respect to VanX, consistent with a convergent evolution of active sites to bind D-Ala-D-Ala and lower energy barriers for formation of the tetrahedral intermediate and transition states. In the N-acyl-D-Ala-D-Ala carboxypeptidase VanY, all active-site residues are conserved (except for the two responsible for recognition of the dipeptide amino terminus). CONCLUSIONS: The mutagenesis results support structure-based functional predictions and explain why the VanX dipeptidase and Ddl ligase show narrow specificity for the D,D-dipeptide substrate. The results reveal that VanX and Ddl, two enzymes that use the same substrate but proceed in opposite directions driven by distinct cofactors (zinc versus ATP), evolved similar architectural solutions to substrate recognition and catalysis acceleration. VanY sequence analysis predicts an active site and mechanism of reaction similar to VanX. (+info)Proficiency of clinical laboratories in and near Monterrey, Mexico, to detect vancomycin-resistant enterococci. (8/1212)
Early detection of vancomycin-resistant enterococci is important for preventing its spread among hospitalized patients. We surveyed the ability of eight hospital laboratories in and near Monterrey, Mexico, to detect vancomycin resistance in Enterococcus spp. and found that although laboratories can reliably detect high-level vancomycin resistance, many have difficulty detecting low-level resistance. (+info)
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Characterization of Enterococcal Community Isolated from an Artisan Istrian Raw Milk Cheese: Biotechnological and Safety Aspects
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Virulence Effect of Enterococcus faecalis Protease Genes and the Quorum-Sensing Locus fsr in Caenorhabditis elegans and Mice |...
First Report on a Randomized Investigation of Antimicrobial Resistance in Fecal Indicator Bacteria from Livestock, Poultry, and...
Glycopeptide Carboxamides Active Against Vancomycin-Resistant Enterococci - PubMed
Enterococcus faecium, SEM - Stock Image C032/2608 - Science Photo Library
Department of Health | Emergence and epidemiology of vancomycin-resistant enterococci in Australia
ASMscience | Screening for Vancomycin
Study Evaluating Vancomycin-Resistant Enterococci in a Hematology Unit - Full Text View - ClinicalTrials.gov
Occurrence of vancomycin-resistant enterococci in chickens in Malaysia | Veterinary Record
Vancomycin Resistant Enterococci (VRE) - Pulse Field Gel Electrophoresis | Public Health Ontario
Water, Sanitation and Hygiene for Development
Pediatric Enterococcal Infection: Background, Pathophysiology, Epidemiology
Vagina artist Megumi Igarashi receives appeal ruling | Nippon...
A clinical isolate of (SP#5) that showed decreased susceptibility to evernimicin - A new family of covalent inhibitors block...
Enterococcus | MARKON
Repositorio da Producao Cientifica e Intelectual da Unicamp: Avaliação de riscos e de pontos críticos de contaminação por...
January | 2016 | fgfr inhibitors
Enterococcus Faecium Fermentation Product Dehydrated | VitaHound
Fecal indicator and pathogenic bacteria and their antibiotic resistance in alluvial groundwater of an irrigated agricultural...
PigProgress - RESEARCH: Enterococcus faecalis pops up during pork processing
Evaluation of Allplex™ Entero-DR assay for detection of antimicrobial resistance determinants from bacterial cultures | BMC...
Thrombocytopenia
Enterococcus spp., Streptococcus agalactiae, Listeria monocytogenes, Escherichia coli, Haemophilus influenzae, Klebsiella ...
Resistencia a antibióticos, a enciclopedia libre
Enterococcus resistente á penicilina, Enterococcus resistente á vancomicina, e Enterococcus resistente a linezolid.[137] ... O Enterococcus faecalis e Enterococcus faecium resistentes a multidrogas están asociados a infeccións nosocomiais ( ... Streptococcus e Enterococcus[editar , editar a fonte]. As infeccións por Streptococcus pyogenes (Streptococcus do grupo A: GAS ... Enterococcus resistente á vancomicina, Acinetobacter baumannii resistente a multifármacos.[15] ...
Uropygial gland
Law-Brown, Janette; Meyers, Paul R. (2003). "Enterococcus phoeniculicola sp. nov., a novel member of the enterococci isolated ... Enterococcus phoeniculicola and Corynebacterium uropygiale). Some of those bacteria add to the antimicrobial properties of ...
Beach advisory
Enterococcus is a large genus of lactic acid phylum Firmicutes Fecal enterococci inhabit gastrointestinal tract of animals. ... Enterococcus bacteria is not harmful by itself, but it indicates harmful bacteria is in the water. These types of bacteria can ... Enterococcus may also cause prostatitis. Prostatitis is the swelling and inflammation of the prostate gland that is located ... Beach advisories are issued after unsafe levels of Enterococcus are detected at sample sites along a body of water, often ...
Anaerobic infection
including Enterococcus spp.), and the most frequently isolated anaerobic bacteria are the B. fragilis group, Peptostreptococcus ... Biliary tract infection is usually caused by E. coli, Klebsiella and Enterococcus spp. Anaerobes (mostly B. fragilis group, and ... These are generally B. fragilis group, Clostridium spp., Enterobacteriaceae and Enterococcus spp. On the other hand, infections ... Empiric use of agents effective against enterococci is recommended and agents effective against methicillin-resistant S. aureus ...
Non-motile bacteria
Vancomycin resistant Enterococcus spp. are non-motile while vancomycin susceptible Enterococcus spp. Some genera have been ... excluding the streptococci and enterococci". Clin Microbiol Rev. 8 (4): 479-95. doi:10.1128/CMR.8.4.479. PMC 172872. PMID ...
Catalase
If not, the organism is 'catalase-negative'. Streptococcus and Enterococcus spp. are catalase-negative. While the catalase test ...
Antibiotic use in livestock
February 2016). "Human health risks associated with antimicrobial-resistant enterococci and Staphylococcus aureus on poultry ... "Surveillance of Enterococcus spp. reveals distinct species and antimicrobial resistance diversity across a One-Health continuum ...
Immunodeficiency
One example is common variable immunodeficiency (CVID) where multiple autoimmune diseases are seen, e.g., inflammatory bowel disease, autoimmune thrombocytopenia and autoimmune thyroid disease. Familial hemophagocytic lymphohistiocytosis, an autosomal recessive primary immunodeficiency, is another example. Pancytopenia, rashes, lymphadenopathy and hepatosplenomegaly are commonly seen in these patients. Presence of multiple uncleared viral infections due to lack of perforin are thought to be responsible. In addition to chronic and/or recurrent infections many autoimmune diseases including arthritis, autoimmune hemolytic anemia, scleroderma and type 1 diabetes are also seen in X-linked agammaglobulinemia (XLA). Recurrent bacterial and fungal infections and chronic inflammation of the gut and lungs are seen in chronic granulomatous disease (CGD) as well. CGD is caused by a decreased production of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase by neutrophils. Hypomorphic RAG mutations ...
List of infectious diseases
Enterococcus infection Enterococcus species Enterovirus infection Enterovirus species Epidemic typhus Rickettsia prowazekii ...
Frederick William Andrewes
... or the enterococcus. Horder, as well as John Hannah Drysdale, Hugh Thursfield, Frank Atcherley Rose, and W. Girling Ball, were ...
Dp-1 holin family
Enterococcus faecalis) and their phage. The genes coding for the lytic system of the pneumococcal phage, Dp-1, has been cloned ... "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis". Science. 299 (5615): 2071-2074. Bibcode: ...
Streptococcus
Group D (enterococci)Edit. Many former group D streptococci have been reclassified and placed in the genus Enterococcus ( ... In 1984, many bacteria formerly considered Streptococcus were separated out into the genera Enterococcus and Lactococcus.[4] ... Köhler W (June 2007). "The present state of species within the genera Streptococcus and Enterococcus". International Journal of ... including E. faecalis, E. faecium, E. durans, and E. avium).[14] For example, Streptococcus faecalis is now Enterococcus ...
Vancomycin
In enterococci, this modification appears to be due to the expression of an enzyme that alters the terminal residue. Three main ... Vancomycin-resistant Enterococcus emerged in 1987. Vancomycin resistance evolved in more common pathogenic organisms during the ... Collignon PJ (August 1999). "Vancomycin-resistant enterococci and use of avoparcin in animal feed: is there a link?". The ... The increasing emergence of vancomycin-resistant enterococci has resulted in the development of guidelines for use by the ...
D-alanine-(R)-lactate ligase
Perichon B, Reynolds P, Courvalin P (September 1997). "VanD-type glycopeptide-resistant Enterococcus faecium BM4339". ... "Purification and characterization of the VanB ligase associated with type B vancomycin resistance in Enterococcus faecalis V583 ... "Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan ...
Oleandomycin
Both can affect Staphylococcus and Enterococcus genera. The MIC for Oleandomycin is 0.3-3 µg/ml for Staphylococcus aureus. ... far less effective than erythromycin in bacterial minimum inhibitory concentration tests involving staphylococci or enterococci ...
Class II bacteriocin
Lactobacillus sakei sakacin P. Enterococcus faecium enterocin A. Enterococcus faecium enterocin P. Leuconostoc gelidum leucocin ... These peptides have some antimicrobial properties; they inhibit the growth of Enterococcus spp. and a few other Gram-positive ... In particular, Bacteriocin AS-48 is a cyclic peptide antibiotic produced by the eubacteria Enterococcus faecalis (Streptococcus ... two antimicrobial peptides produced by Enterococcus faecalis BFE 1071". Appl. Environ. Microbiol. 66 (4): 1298-304. doi:10.1128 ...
Hemolysis
The genus Enterococcus includes lactic acid bacteria formerly classified as gamma-hemolytic Group D in the genus streptococcus ... Enterococcus, and Staphylococcus), some parasites (e.g., Plasmodium), some autoimmune disorders (e.g., drug-induced hemolytic ...
Sortase
Kemp KD, Singh KV, Nallapareddy SR, Murray BE (November 2007). "Relative contributions of Enterococcus faecalis OG1RF sortase- ... a second pilus gene cluster in Enterococcus faecalis?". Current Microbiology. 59 (2): 206-11. doi:10.1007/s00284-009-9422-y. ... "Endocarditis and biofilm-associated pili of Enterococcus faecalis". The Journal of Clinical Investigation. 116 (10): 2799-807. ...
Preening
Enterococcus faecalis did this by releasing a bacteriocin. Female hoopoes transfer preen oil onto their brood patches and eggs ... One study of Eurasian hoopoes showed that the presence of symbiotic bacteria (Enterococcus faecalis) in their preen oil ...
Cefpirome
Bacteroides fragilis, enterococci, Pseudomonas spp. and staphylococci are resistant to cefpirome sulfate, and some Haemophilus ...
GrpE
... is found in the genome of Enterococcus faecilis and Enterococcus faecium and is critical for enterococcal biofilm ... Enterococci are bacteria that are commonly found in the gastrointestinal tract of animals, including humans. These bacteria can ... Gilmore MS, Clewell DB, Ike Y, Shankar N (2014). Gilmore MS, Clewell DB, Ike Y, Shankar N (eds.). "Enterococci: From Commensals ... Ch'ng JH, Chong KK, Lam LN, Wong JJ, Kline KA (January 2019). "Biofilm-associated infection by enterococci". Nature Reviews. ...
Enterococcaceae
Representative genera include Enterococcus, Melissococcus, Pilibacter, Tetragenococcus, and Vagococcus. In this family are some ...
Mezlocillin
... aeruginosa Serratia marcescens Enterococcus faecalis Peptococcus spp. Peptostreptococcus spp. Mezlocillin can be made in a ...
Hand sanitizer
Pidot, Sacha J.; Gao, Wei; Buultjens, Andrew H. (1 August 2018). "Increasing tolerance of hospital Enterococcus faecium to ...
D-alanine-D-serine ligase
Dutka-Malen S, Molinas C, Arthur M, Courvalin P (March 1992). "Sequence of the vanC gene of Enterococcus gallinarum BM4174 ... Depardieu F, Bonora MG, Reynolds PE, Courvalin P (November 2003). "The vanG glycopeptide resistance operon from Enterococcus ... in Enterococcus casseliflavus". Microbial Drug Resistance. 15 (1): 1-9. doi:10.1089/mdr.2009.0856. PMID 19216682. D-alanine-D- ... and characterization of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase". Proceedings of the National Academy of ...
Butanol fuel
"Screened Butanol-Tolerant Enterococcus faecium Capable of Butanol Production". Applied Biochemistry and Biotechnology. 168 (6 ...
Na+-transporting two-sector ATPase
"Operon of vacuolar-type Na+-ATPase of Enterococcus hirae". J. Biol. Chem. 269 (13): 9453-9. PMID 8144530. Takase K, Kakinuma S ... "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na+-translocating ATPase of Enterococcus hirae". J. ...
Ascending cholangitis
Enterococcus causes 10-20%. Given that ascending cholangitis usually occurs in the setting of bile duct obstruction, various ...
Indoor tanning
aeruginosa and putida), Bacillus spp., Klebsiella pneumoniae, Enterococcus species, Staphylococcus aureus, and Enterobacter ...
Enterococcus faecalis - Wikipedia
Wikimedia Commons has media related to Enterococcus faecalis.. *Type strain of Enterococcus faecalis at BacDive - the Bacterial ... as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov". International Journal of Systematic Bacteriology. 34 ( ... Prior to 1984, enterococci were members of the genus Streptococcus; thus, E. faecalis was known as Streptococcus faecalis.[24] ... Enterococcus faecalis - formerly classified as part of the group D Streptococcus system - is a Gram-positive, commensal ...
Enterococcus | bacteria genus | Britannica
Enterococcus - Wikipedia
Parte, A.C. "Enterococcus". LPSN. LPSN LPSN entry for Enterococcus Gilmore MS; et al., eds. (2002). The Enterococci: ... Enterococcus is a large genus of lactic acid bacteria of the phylum Firmicutes. Enterococci are gram-positive cocci that often ... Enterococci typically exhibit gamma-hemolysis on sheeps blood agar. Members of the genus Enterococcus (from Greek έντερο, ... as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov". Int. J. Syst. Bacteriol. 34: 31-34. doi:10.1099/ ...
Copper homeostasis in Enterococcus hirae. - PubMed - NCBI
Enterococcus faecium EnGen0006
Enterococcus haemoperoxidus - Wikipedia
Enterococcus haemoperoxidus is a species of Enterococcus with type strain CCM 4851T (= LMG 19487T). Svec P, Devriese LA, ... 2001). "Enterococcus haemoperoxidus sp. nov. and Enterococcus moraviensis sp. nov., isolated from water". Int J Syst Evol ... "Enterococcus haemoperoxidus" at the Encyclopedia of Life LPSN Type strain of Enterococcus haemoperoxidus at BacDive - the ... "Evaluation of ribotyping for characterization and identification of Enterococcus haemoperoxidus and Enterococcus moraviensis ...
Enterococcus | Food Safety News
Enterococcus faecium - Wikipedia
Enterococcus faecium is a Gram-positive, alpha-hemolytic or nonhemolytic bacterium in the genus Enterococcus.[1] It can be ... Vancomycin-resistant EnterococciEdit. Enterococcus faecium has been a leading cause of multi-drug resistant enterococcal ... "In Gilmore MS, Clewell DB, Ike Y. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection. PMID 24649504.. ... Enterococci: From Commensals to Leading Causes of Drug Resistant Infection. Boston: Massachusetts Eye and Ear Infirmary. PMID ...
Vancomycin-Resistant Enterococcus
Resistant Enterococcus: Enterococci impart resistance to antibiotics in a variety of ways. Although some species are inherently ... Transmission: Enterococci are part of the normal gastrointestinal (GI) flora. Once Enterococcus species colonize the GI tract, ... ABSTRACT: Vancomycin-resistant Enterococcus (VRE) is a major cause of hospital-acquired infections in the United States. ... Enterococcus gallinarum, Enterococcus casseliflavus) cases.5 Literature suggests QPD as an alternative for severe infections ...
The rise of the Enterococcus: beyond vancomycin resistance. - PubMed - NCBI
c. Enterococci take advantage of this reduction in REGIIIγ secretion to become the dominant members of the gut microbiota. IL- ... In Enterococcus faecium, resistance to ampicillin occurs through the production of penicillin-binding protein 5 (PBP5), which ... Enterococci exhibit intrinsic low-level resistance to aminoglycosides such as streptomycin or gentamicin owing to low uptake of ... Resistance of Enterococcus spp. to the streptogramin quinupristin-dalfopristin (Q-D) involves several pathways, including drug ...
What are common causes of enterococcus? | Reference.com
Common causes of enterococcus infection include patients being infected by hospital workers or others who have not practiced ... They are Enterococcus faecium and Enterococcus faecalis. As their names imply, they are found in the digestive tract of humans ... Common causes of enterococcus infection include patients being infected by hospital workers or others who have not practiced ... Moreover, Enterococcus faecalis is not only resistant to cephalosporins, but people who have taken cephalosporins are at ...
Vancomycin-resistant enterococci - hospital: MedlinePlus Medical Encyclopedia
Enterococcus is a germ (bacteria). It normally lives in the intestines and in the female genital tract. ... But enterococcus can cause an infection if it gets into the urinary tract, bloodstream, or skin wounds or other sterile sites. ... Enterococcus species, Streptococcus gallolyticus group, and leuconostoc species. In: Bennett JE, Dolin R, Blaser MJ, eds. ... Enterococcus is a germ (bacteria). It normally lives in the intestines and in the female genital tract. ...
Characteristics of Enterococcus Faecalis | LIVESTRONG.COM
Enterococcus faecalis is the most commonly isolated of the genera. According to Elmer Koneman, M.D., it is associated with 80 ... Enterococcus faecalis and all of the enterococci are closely related to the streptococci and appear microscopically as spheres ... One of the most important and serious factors about Enterococcus faecalis and the other enterococci is its resistance to a ... Enterococcus faecalis, as the name implies, is found normally in the intestines of humans, animals and birds. It is also found ...
Culture- Bacterial, Vancomycin Resistant Enterococcus Screen
Vancomycin-Resistant Enterococci (VRE) Symptoms & Treatment
Read about vancomycin-resistant enterococci (VRE) causes and treatment. Symptoms and signs depend upon the site of VRE ... Enterococci (genus Enterococcus) are bacteria that commonly live in the bowel and are usually resistant to many antibiotics. ... The two main species that cause problems are vancomycin-resistant Enterococcus faecium and vancomycin-resistant Enterococcus ... Vancomycin-Resistant Enterococci (VRE). *Medical Author: Charles Patrick Davis, MD, PhD *Medical Editor: Melissa Conrad ...
QuantiTray - Enterococcus
Eurofins EMLab P&K is the leading commercial IAQ laboratory in North America and specializes in analyzing samples to identify mold, bacteria (including Legionella, E. coli, Endotoxins, etc.), asbestos, and radon. Eurofins EMLab P&K partners with environmental professionals who make important decisions about the indoor environment that affect the health of our communities. We use science and innovation to provide accurate data that people trust and to create solutions that save time and resources. ...
Vancomycin-resistant Enterococci (VRE) and the Clinical Laboratory
| HAI | CDC
What are the types of vancomycin resistance in enterococci? There are the two types of vancomycin resistance in enterococci. ... The second type of vancomycin resistance in enterococci is acquired resistance. Enterococci can become resistant to vancomycin ... Several genes, including vanA, vanB, vanC, vanD, and vanE, contribute to resistance to vancomycin in enterococci. ... Isolates of Enterococcus gallinarum and E. casseliflavus/E. flavescens demonstrate an inherent, low-level resistance to ...
Enterococcus hirae Farrow and Collins ATCC ® 8043™
Enterococcus hirae ATCC ® 8043™ Designation: R TypeStrain=True Application: Assay of folic acid Assay of monensin Quality ... Enterococcus hirae Farrow and Collins (ATCC® 8043™) Strain Designations: R [BUCSAV 308, CCM 2423, CCM 2424, DSM 20160, JCM 8729 ... Enterococcus hirae, a new species that includes amino acid assay strain NCDO 1258 and strains causing growth depression in ... Nucleotide (GenBank) : AJ387916 Enterococcus hirae partial sodA gene for superoxide dismutase, strain CIP 53.48 T (ATCC 8043). ...
Enterococcus - Simple English Wikipedia, the free encyclopedia
as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov.". Int. J. Sys. Bacteriol. 34: 31-34. doi:10.1099/ ... Enterococci are Gram-positive cocci that often occur in pairs or short chains. They look like streptococci.[1] Two species are ... 2002). The Enterococci: pathogenesis, molecular biology, and antibiotic resistance. Washington, D.C.: ASM Press. ISBN 978-1- ... Members of the genus Enterococcus were classified as Group D Streptococcus until 1984. Genomic DNA analysis showed they were a ...
The ecology, epidemiology and virulence of Enterococcus
Enterococci are Gram-positive, catalase-negative, non-spore-forming, facultative anaerobic bacteria, which usually inhabit the ... The ecology, epidemiology and virulence of Enterococcus Microbiology (Reading). 2009 Jun;155(Pt 6):1749-1757. doi: 10.1099/mic. ... Virulence factors of enterococci include the extracellular protein Esp and aggregation substances (Agg), both of which aid in ... Enterococci are Gram-positive, catalase-negative, non-spore-forming, facultative anaerobic bacteria, which usually inhabit the ...
Enterococcus - Wikipedia, a enciclopedia libre
as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov.". Int. J. Sys. Bacteriol. 34: 31-34. doi:10.1099/ ... Enterococcus é un xénero de bacterias do ácido láctico do filo Firmicutes. Os enterococos son cocos grampositivos, que adoitan ... 2002). The Enterococci: Pathogenesis, Molecular Biology, and Antibiotic Resistance. Washington, D.C.: ASM Press. ISBN 978-1- ... Schleifer KH; Kilpper-Balz R (1984). "Transfer of Streptococcus faecalis and Streptococcus faecium to the genus Enterococcus ...
Talk:Enterococcus virus FL2 - Wikispecies
RCSB PDB - 2AWD: Crystal structure of LacC from Enterococcus faecalis
Enterococcus / Elephant Man Behind The Sun - Split (Cassette) at Discogs
Enterococcus faecium - microbewiki
Enterococcus faecium - microbewiki
"Virulence Factors of Enterococcus faecium and Enterococcus faecalis Strains Isolated from Humans and Pets" Turk. J. Vet. Anim. ... as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov." Int. J. Syst. Bacteriol. (1984) 34:31-34. ... Enterococcus faecium (2) Description and significance. E. faecium is a human pathogen that causes nosocomial bacteremia, ... The sequencing of a vacomycin resistant E. faecalis strain, Enterococcus facalis V583, revealed 1 circular chromosome and 3 ...
Enterococcus faecalis Heme-Dependent Catalase | Journal of Bacteriology
Enterococcus faecalis cells cannot synthesize porphyrins and do not rely on heme for growth but can take up heme and use it to ... Multiple-drug resistant enterococci: the nature of the problem and an agenda for the future. Emerg. Infect. Dis.4:239-249. ... Enterococcus faecalis Heme-Dependent Catalase Message Subject (Your Name) has forwarded a page to you from Journal of ... Enterococcus faecalis, formerly known as Streptococcus faecalis, is a gram-positive bacterium with a low G+C content in its ...
Multiple posttranscriptional regulatory mechanisms partner to control ethanolamine utilization in Enterococcus faecalis | PNAS
2007) Enterococcus faecalis Mutations Affecting Virulence in the C. elegans Model Host. Infect Immun 75:2634-2637. ... 2000) Enterococcus faecalis adhesin, ace, mediates attachment to extracellular matrix proteins collagen type IV and laminin as ... 2003) Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. Science 299:2071-2074. ... 2002) in The Enterococci, Pathogenesis, Molecular Biology, and Antibiotic Resistance, ed Gilmore MS (American Society for ...
Enterococci Monitoring News on Environmental XPRT
Get the latest enterococci monitoring news on Environmental XPRT, the worlds largest environmental industry marketplace and ... Rapid, online detection of enterococci and of the total microbial activity in water Recently KWR presented an article about an ... innovative project: the rapid online detection of enterococci and of the total microbial activity in water. MicroLAN is partner ...
StrainsBacteriaGenusStreptococcusIsolatesSpeciesResistantAntibioticsInfectionEndocarditisAntibiotic ResistanceEpidemiologyPathogenClinicalBacteremiaHiraeFaecium and Enterococcus faecalisHumansEscherichiaDetection of enterococciFecalATCCBacterialStrainOrganismsInfections causedColonizationAmong enterococciIntestinal enterococciFirmicutesPathogenesisGenesDeterminantsMicrobiotaConcentrations2017PathogenicAmpicillin-SusceptibleFacultatively anaerobicAntimicrobial ResistanceHospitalGenome sequences
Strains15
- In the last two decades, particularly virulent strains of Enterococcus that are resistant to vancomycin (vancomycin-resistant Enterococcus, or VRE) have emerged in nosocomial infections of hospitalized patients, especially in the US. (wikipedia.org)
- Though some strains of enterococcus are defeated with courses of vancomycin or ampicillin, the bacteria is notorious for being resistant to antibiotics, claims Phage Therapy Center. (reference.com)
- There are two major strains of enterococcus bacteria, states Phage Therapy Center. (reference.com)
- The new strains are called vancomycin-resistant enterococci (VRE). (rxlist.com)
- Farrow JA, Collins MD. Enterococcus hirae, a new species that includes amino acid assay strain NCDO 1258 and strains causing growth depression in young chickens. (atcc.org)
- [4] Urinary tract infections can be treated by antibiotics , but many virulent strains of Enterococcus are resistant . (wikipedia.org)
- were first compared in terms of sensitivity using (1) 41 different type strains of Enterococcus spp. (environmental-expert.com)
- Some strains of the genus Enterococcus are effective probiotic bacteria if they meet safety and probiotic criteria. (springer.com)
- PCR detection of resistance genes ( vanA , vanB , vanC , tetM , tetL , ermB , and mefA ) revealed the presence of mefA gene in five Enterococcus faecium strains and vanA gene in one strain. (springer.com)
- Concerns regarding increased prevalence of daptomycin (DAP)-resistant strains necessitate novel therapies for Enterococcus faecium infections. (nih.gov)
- Over the last 20 years, certain antibiotic-resistant, infectious strains of enterococci, including E. faecium , have been identified in hospital patients. (thepigsite.com)
- Enterococcus faecium strains are resistant to penicillin through the overproduction of low-affinity penicillin-binding protein PBP5 [1]. (esrf.eu)
- Here, we isolated 13 Enterococcus faecalis strains possessing a linezolid MIC of ≥4 mg/liter from nursery pigs in swine herds located across Brazil. (asm.org)
- Enterococcus faecium strains are commonly resistant to vancomycin and β-lactams. (asm.org)
- Just a few drugs such as linezolid show bacteriostatic activity against vancomycin-resistant strains of E. faecium and E. faecalis, and a combination of quinupristin and dalfopristin, which have bactericidal activity against most drug-resistant staphylococci , streptococci , and pneumococci , appears to be bacteriostatic against E. faecium, and is not active against Enterococcus faecalis [ 12 ]. (mdpi.com)
Bacteria26
- Enterococci, a type of bacteria, can cause serious infections for patients in healthcare settings, including bloodstream, surgical site, and urinary tract infections. (cdc.gov)
- Enterococcus is a large genus of lactic acid bacteria of the phylum Firmicutes. (wikipedia.org)
- Enterococcus bacteria occur naturally in the human body. (reference.com)
- Enterococcus is a germ (bacteria). (medlineplus.gov)
- These resistant bacteria are called vancomycin-resistant enterococci (VRE). (medlineplus.gov)
- Enterococci (genus Enterococcus) are bacteria that commonly live in the bowel and are usually resistant to many antibiotics. (rxlist.com)
- Enterococci are a group of gram -positive, round -shaped bacteria that commonly live in the gut, although they can cause infection anywhere in the body. (rxlist.com)
- Vancomycin resistance is acquired when a sensitive Enterococcus acquires a special piece of DNA called a plasmid that permits the bacteria to become resistant to vancomycin. (rxlist.com)
- Enterococci are Gram-positive, catalase-negative, non-spore-forming, facultative anaerobic bacteria, which usually inhabit the alimentary tract of humans in addition to being isolated from environmental and animal sources. (nih.gov)
- The concentration of enterococci, bacteria that thrive in feces, has long been the federal standard for determining water quality. (news-medical.net)
- Enterococcus , a Gram-positive facultative anaerobic cocci belonging to the lactic acid bacteria of the phylum Firmicutes, is known to be able to resist a wide range of hostile conditions such as different pH levels, high concentration of NaCl (6.5%), and the extended temperatures between 5°C and 65°C. Despite being the third most common nosocomial pathogen, our understanding on its virulence factors is still poorly understood. (hindawi.com)
- The invention concerns a culture medium for isolating enterococcus comprising violet crystal, and preferably gram-negative bacteria inhibitors and chromogens. (freepatentsonline.com)
- 1. A culture medium for detecting and/or distinguishing enterococci, characterized in that it contains, in a culture medium for enterococci, Crystal Violet at a concentration allowing the growth of enterococci and the inhibition of the growth of most Gram-positive bacteria, said concentration being between 0.1 and 1.5 mg/l. (freepatentsonline.com)
- Vancomycin-resistant Enterococcus faecium (VRE) is a bacteria that generally infects the blood, urinary tract and wounds. (yourlawyer.com)
- Enterococci are well-known bacteria and are found in abundance in the gastrointestinal tract of both animals and humans. (thepigsite.com)
- Vancomycin resistant enterococci represent one such example of a prominent nosocomial pathogen on which nation-wide population analyses on prevalent lineages are scarce and data on how the bacteria acquire resistance, especially of the vanB genotype, are still under debate. (nature.com)
- Coloured scanning electron micrograph (SEM) of a clump of Enterococcus faecalis bacteria. (sciencephoto.com)
- Enterococci are bacteria that live in the gastrointestinal tract (bowels) of most individuals and generally do not cause harm. (tbrhsc.net)
- Enterococci are a clinically important group of bacteria for humans and animals. (semanticscholar.org)
- IMPORTANCE For many bacteria, including the opportunistically pathogenic enterococci, antibiotic resistance is mediated by acquisition of new DNA and is frequently encoded on mobile DNA elements such as plasmids and transposons. (asm.org)
- Enterococcus belongs to the Enterococcaceae family, the members of which are symbiotic bacteria in the human intestine ( 1 ). (spandidos-publications.com)
- The genus Enterococcus comprises a ubiquitous group of Gram-positive bacteria that are of great relevance to human health for their role as major causative agents of health care-associated infections. (asm.org)
- Fecal pollution is measured in surface waters using culture-based measurements of enterococci and Escherichia coli bacteria. (epa.gov)
- Since our previous study revealed that several licorice phenolics have antibacterial effects on methicillin-resistant Staphylococcus aureus (MRSA), and suppressive effects on the oxacillin resistance of MRSA, we further investigated effectiveness of licorice constituents on vancomycin-resistant Enterococcus (VRE) bacteria, and purified 32 phenolic compounds. (mdpi.com)
- Among drug-resistant bacteria vancomycin-resistant Enterococci (VRE) is a serious menace for patients in hospitals. (mdpi.com)
- Bloodstream infection by highly antibiotic-resistant bacteria, such as vancomycin-resistant Enterococcus (VRE), is a growing clinical problem that increasingly defies medical intervention. (jci.org)
Genus9
- [1] [2] Like other species in the genus Enterococcus , E. faecalis is found in healthy humans, but can cause life-threatening infections, especially in the nosocomial (hospital) environment, where the naturally high levels of antibiotic resistance found in E. faecalis contribute to its pathogenicity. (wikipedia.org)
- Members of the genus Enterococcus (from Greek έντερο, éntero, "intestine" and κοκκος, coccos, "granule") were classified as group D Streptococcus until 1984, when genomic DNA analysis indicated a separate genus classification would be appropriate. (wikipedia.org)
- Transfer of Streptococcus faecalis and Streptococcus faecium to the genus Enterococcus nom. (wikipedia.org)
- Enterococcus faecium is a Gram-positive , alpha-hemolytic or non hemolytic bacterium in the genus Enterococcus . (wikipedia.org)
- The genus Enterococcus includes some of the most important nosocomial multidrug-resistant organisms, and these pathogens usually affect patients who are debilitated by other, concurrent illnesses and undergoing prolonged hospitalization. (nih.gov)
- Members of the genus Enterococcus were classified as Group D Streptococcus until 1984. (wikipedia.org)
- Automated systems may present problems in the identification of members of the genus Enterococcus in clinical laboratories. (scielo.br)
- In 1984, Schleifer et al ( 5 ) indicated that they belonged to the Enterococcus genus via DNA-DNA and DNA-rRNA hybridization. (spandidos-publications.com)
- It is worth noting that these organisms were previously classified as belonging to the genus " Streptococc us" but were placed in their own genus, " Enterococcus ," after genetic analysis (DNA-DNA reassociation analysis and 16S rRNA sequencing) showed they were too different to be grouped with the streptococci. (psychiatryadvisor.com)
Streptococcus7
- Enterococcus faecalis - formerly classified as part of the group D Streptococcus system - is a Gram-positive , commensal bacterium inhabiting the gastrointestinal tracts of humans. (wikipedia.org)
- Listeria, MRSA, Streptococcus, and Enterococcus can all be identified much quicker by the Verigene GP Blood Culture Nuclear Acid Test (BC-GP), which got marketing approval from the U.S, Food and Drug Administration (FDA). (foodsafetynews.com)
- Enterococcus species, Streptococcus gallolyticus group, and leuconostoc species. (medlineplus.gov)
- Membros do xénero Enterococcus eran clasificados ata 1984 como Streptococcus do grupo D, pero as análises xenómicas indicaron que era máis apropiado clasificalas nun xénero separado. (wikipedia.org)
- Enterococcus faecalis , formerly known as Streptococcus faecalis , is a gram-positive bacterium with a low G+C content in its genomic DNA. (asm.org)
- Coloured scanning electron micrograph (SEM) of Enterococcus faecium (also known as Streptococcus faecium), Gram-positive, vancomycin resistant (VRE), coccus prokaryote that grows in groups or chains. (sciencephoto.com)
- These changes were also confirmed in 'Bergey's Manual of Systematic Bacteriology Volume 3: The Firmicutes' in 2009, such that ' Streptococcus faecalis ' was revised to Enterococcus faecalis , and ' Streptococcus faecium ' was revised to E. faecium ( 6 ). (spandidos-publications.com)
Isolates12
- Isolates of Enterococcus gallinarum and E. casseliflavus/E. flavescens demonstrate an inherent, low-level resistance to vancomycin. (cdc.gov)
- For this purpose, 79 clinical isolates of Malaysian enterococci were evaluated for the presence of virulence genes. (hindawi.com)
- In our study, 17 canine enterococci previously selected from a group of 160 isolates based on safety criteria were screened for some functional properties relevant to their use as probiotics. (springer.com)
- In the United States they have become major nosocomial pathogens, rising in incidence from 0.3% in 1989 to 7.9% in 1993 as reported by the CDC, 1 and among patients in intensive-care units, now representing 14% of blood culture isolates of enterococci. (health.gov.au)
- Clinical isolates of Enterococcus spp. (health.gov.au)
- In general, the Mallard and wastewater enterococci isolates belonged to different phenotypes, although several sharing identical phenotypic profiles were found. (diva-portal.org)
- Having conventional physiological tests as the reference method, we evaluated the use of an automated system (VITEK bioMérieux) in the identification of 80 isolates belonging to different species of Enterococcus. (scielo.br)
- The in vitro activities of ceftaroline and tedizolid were compared against Staphylococcus aureus , Enterococcus faecalis , and Enterococcus faecium clinical isolates collected from the China Antimicrobial Surveillance. (asm.org)
- High-level aminoglycoside resistance was noted in 30.0% of Enterococcus faecalis and 25.2% of Enterococcus faecium isolates. (asm.org)
- This study aimed to evaluate the in vitro antimicrobial activity, heteroresistance emergence, and resistance mechanism of omadacycline (OMC) in clinical Enterococcus faecalis isolates from China. (asm.org)
- Clinical isolates of Enterococcus faecalis aggregate human platelets. (lu.se)
- Here we report for the first time that many clinical isolates of Enterococcus faecalis, a common pathogen in infective endocarditis, aggregate human platelets. (lu.se)
Species14
- Enterococcus haemoperoxidus is a species of Enterococcus with type strain CCM 4851T (= LMG 19487T). (wikipedia.org)
- Enterococcus species are a leading cause of hospital-acquired infections and the second most common nosocomial bloodstream pathogen in the United States. (uspharmacist.com)
- Once Enterococcus species colonize the GI tract, the development of antibiotic resistance increases, as does the risk of transmission between patients and providers. (uspharmacist.com)
- The two main species that cause problems are vancomycin-resistant Enterococcus faecium and vancomycin-resistant Enterococcus faecalis . (rxlist.com)
- Understanding the ecology, epidemiology and virulence of Enterococcus species is important for limiting urinary tract infections, hepatobiliary sepsis, endocarditis, surgical wound infection, bacteraemia and neonatal sepsis, and also stemming the further development of antibiotic resistance. (nih.gov)
- In this work, we describe a unique series of posttranscriptional regulatory strategies that influence expression of ethanolamine utilization genes ( eut ) in Enterococcus , Clostridium , and Listeria species. (pnas.org)
- Although the host species targeted by BoNT/En remains to be determined, these findings establish an extended member of BoNTs and demonstrate the capability of E. faecium, a commensal organism ubiquitous in humans and animals and a leading cause of hospital-acquired multi-drug-resistant (MDR) infections, to horizontally acquire, and possibly disseminate, a unique BoNT gene cluster. (diva-portal.org)
- Identification of Enterococcus species and phenotypically similar Lactococcus and Vagococcus species by reverse checkerboard hybridization to chaperonin 60 gene sequences. (semanticscholar.org)
- nov. a new Enterococcus species from human sources. (semanticscholar.org)
- The characteristics, diagnosis, management, surveillance and epidemiology Enterococcus species and Glycopeptide Resistant Enterococci (GRE). (cardinaloconnorconference.com)
- 1 , 2 The two most common species, Enterococcus faecalis and E. faecium , can harbour vanA and vanB genes, which encode resistance to vancomycin and have been implicated in the development of persistent, transmissible nosocomial infections that may be associated with poor outcomes. (mja.com.au)
- Enterococcus faecalis and Enterococcus faecium have similar morphologies, leading to confusion between the two species. (spandidos-publications.com)
- However, numerous species of Enterococci possess the ability to transfer and carry antibiotic resistance genes ( 7 ). (spandidos-publications.com)
- The enterococci are resilient and versatile species able to survive under harsh conditions, making them well adapted to the health care environment. (asm.org)
Resistant47
- Some enterococci are intrinsically resistant to β-lactam-based antibiotics (penicillins, cephalosporins, carbapenems), as well as many aminoglycosides. (wikipedia.org)
- Enterococcus faecium has been a leading cause of multi-drug resistant enterococcal infections over Enterococcus faecalis in the United States. (wikipedia.org)
- ABSTRACT: Vancomycin-resistant Enterococcus (VRE) is a major cause of hospital-acquired infections in the United States. (uspharmacist.com)
- Infections caused by vancomycin-resistant Enterococcus (VRE) have rapidly emerged as a predominant concern, particularly among vulnerable patient populations. (uspharmacist.com)
- The effects of antibiotics on the gut microbiota and on colonization with vancomycin-resistant enterococci are highlighted, including how enterococci benefit from the antibiotic-mediated eradication of gram-negative members of the gut microbiota. (nih.gov)
- Finally, we review the most important mechanisms of resistance to the antibiotics that are used to treat vancomycin-resistant enterococci. (nih.gov)
- Moreover, Enterococcus faecalis is not only resistant to cephalosporins, but people who have taken cephalosporins are at greater risk for enterococcus faecalis infection. (reference.com)
- Enterococcus germs can become resistant to vancomycin and therefore are not killed. (medlineplus.gov)
- VRE are enterococci that have become resistant to the antibiotic vancomycin . (rxlist.com)
- In recent decades, however, some enterococci have become resistant to vancomycin. (rxlist.com)
- Enterococci can become resistant to vancomycin by acquisition of genetic information from another organism. (cdc.gov)
- In some instances, enterococci have become resistant to this drug and thus are called vancomycin-resistant enterococci (VRE). (medic8.com)
- The sequencing of a vacomycin resistant E. faecalis strain, Enterococcus facalis V583 , revealed 1 circular chromosome and 3 plasmids. (kenyon.edu)
- High prevalence of multidrug-resistant Escherichia coli and Enterococcus spp. (environmental-expert.com)
- Vancomycin-resistant Enterococcus faecium (VREF) has recently emerged as an important threat in U.S. hospitals ( 5 , 24 ). (asm.org)
- From a Canadian public policy perspective, the greatest sustained value of the facility would be tracking, research and containment of hospital acquired infections such as C. difficile , Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant enterococcus . (stephentaylor.ca)
- Thus, the present study provides a better understanding of how enterococci emerge into successful multidrug-resistant nosocomial pathogens. (nature.com)
- Due to their often multi-drug resistant phenotype only a few therapeutic options are left to treat infections caused by vancomycin-resistant enterococci (VRE). (nature.com)
- Vancomycin-resistant Enterococcus faecium and E. faecalis (VRE) were first described in Britain in 1988 and soon afterwards were reported from other European countries and the United States. (health.gov.au)
- From April 1, 2014, to March 31, 2015, 89 healthcare facilities took part in the surveillance of healthcare-associated vancomycin-resistant enterococci (VRE) infections, for a combined total of 4,839,578 patient days (Table 1). (inspq.qc.ca)
- Daptomycin has become a mainstay therapy for the treatment of serious vancomycin-resistant Enterococcus faecium infections. (asm.org)
- Vancomycin-resistant enterococci (VRE) first appeared in the late 1980s in a few European countries. (eurosurveillance.org)
- vancomycin-resistant Enterococcus faecalis are still rare. (eurosurveillance.org)
- The spokesperson for Queen Elizabeth Hospital (QEH) announced today (September 30) that due to the rising trend of Vancomycin Resistant Enterococci (VRE) carriers screened in the hospital in recent months, pan-screening of VRE carriers will commence today upon expert microbiologist advice. (gov.hk)
- The "Vancomycin-Resistant Enterococcus Faecium Infections - Pipeline Insight, 2019" drug pipelines has been added to ResearchAndMarkets.com's offering. (pharmiweb.com)
- This report offers comprehensive Insight of the pipeline (under development) therapeutics scenario and growth prospects across Vancomycin-Resistant Enterococcus Faecium Infections development. (pharmiweb.com)
- The report assesses the active Vancomycin-Resistant Enterococcus Faecium Infections pipeline products by developmental stage, product type, molecule type, and administration route. (pharmiweb.com)
- Effects on the Emergence and Transmission of Vancomycin-Resistant Enterococci After Changes in Antibiotic Use in a Hematology Unit. (clinicaltrials.gov)
- Because mobile elements constitute up to 25% of the genome of multidrug-resistant (MDR) enterococci, it was of interest to examine the codistribution of CRISPR and acquired antibiotic resistance in enterococcal lineages. (asm.org)
- Enterococcus faecalis and Enterococcus faecium rank among the leading causes of antibiotic-resistant hospital-acquired bacterial infections ( 1 - 3 ). (asm.org)
- Resistance to last-line drugs, such as vancomycin ( 4 ), is common, and enterococci are now disseminating this resistance to methicillin-resistant Staphylococcus aureus (MRSA) ( 5 - 7 ). (asm.org)
- The epidemiology of vancomycin-resistant Enterococcus faecium (VREF) in Europe is characterized by a large community reservoir. (cdc.gov)
- The emergency of vancomycin resistant enterococci who may need treatment with vancomycin where other antibiotics have failed. (cardinaloconnorconference.com)
- In this Article These superbugs are called vancomycin-resistant enterococci, or VRE. (cardinaloconnorconference.com)
- vancomycin and are known as vancomycin-resistant enterococcus or VRE. (cardinaloconnorconference.com)
- Probiotic treatment of vancomycin-resistant enterococci: a randomised controlled trial. (cardinaloconnorconference.com)
- Vancomycin Resistant Enterococci 2 Guideline for Vancomycin Resistant Enterococci All Departments involved in patient care and treatment e.g. (cardinaloconnorconference.com)
- Vancomycin-resistant Enterococci With VRE, it means vancomycin is not effective in with VRE do not usually need treatment. (cardinaloconnorconference.com)
- To determine whether eating Lactobacillus rhamnosus GG (LGG) in the form of commercially available yoghurt improves clearance of vancomycin-resistant enterococci (VRE). (mja.com.au)
- Over the past 10-15 years, there has been a rapid increase in the prevalence of vancomycin-resistant enterococci (VRE). (mja.com.au)
- The complete genome sequence of Enterococcus faecalis V583, a vancomycin-resistant clinical isolate, revealed that more than a quarter of the genome consists of probable mobile or foreign DNA. (jcvi.org)
- Vancomycin-resistant Enterococcus faecium meningitis in adults: Case series and review of the literature. (biomedsearch.com)
- Background: Vancomycin-resistant Enterococcus faecium (VR E. faecium) is a rare cause of meningitis and is associated with substantial mortality. (biomedsearch.com)
- This is called vancomycin-resistant enterococci (VRE) infection. (doctors-hospital.net)
- Enterococcus are intrinsically resistant to many of the antibiotics used in clinical practice. (unl.pt)
- After the introduction of this antibiotic into the clinical practice in the 80s, the first report of VRE (Vancomycin-Resistant Enterococcus) appreared soon in 1986. (unl.pt)
- This compound is frequently used to treat vancomycin-resistant enterococci (VRE). (psychiatryadvisor.com)
Antibiotics4
- Enterococci impart resistance to antibiotics in a variety of ways. (uspharmacist.com)
- One of the most important and serious factors about Enterococcus faecalis and the other enterococci is its resistance to a variety of antibiotics. (livestrong.com)
- The nosocomial pathogenicity of enterococci has emerged in recent years, as well as increasing resistance to glycopeptide antibiotics. (nih.gov)
- However, in the last decades, due to the increased use of antibiotics, both in animal breeding and in Hospitals and veterinary clinical practice, enterococci became a major concern in terms of nosocomial and community acquired infections. (unl.pt)
Infection14
- Enterococcus infections, including VRE infections, cause a range of different symptoms depending on the location of the infection. (wikipedia.org)
- Common causes of enterococcus infection include patients being infected by hospital workers or others who have not practiced good hygiene such as hand-washing, says the National Institutes of Health. (reference.com)
- Diseases that are caused by an enterococcus infection include urinary tract infections, endocarditis, meningitis and bacteremia, notes Phage Therapy Center. (reference.com)
- Diverticulitis, a disease of the bowel, can also be caused by enterococcus infection. (reference.com)
- Unfortunately, enterococcus infection is a great risk for patients whose immune systems are already compromised. (reference.com)
- But enterococcus can cause an infection if it gets into the urinary tract, bloodstream, or skin wounds or other sterile sites. (medlineplus.gov)
- Patients with the enterococcus germ who do not have symptoms of an infection do not need treatment. (medlineplus.gov)
- Aortic valve endocarditis from Enterococcus hirae infection. (medworm.com)
- Outside healthcare settings, enterococci very rarely present a risk of infection for humans. (thepigsite.com)
- This study was performed to evaluate the impacts of vanA positivity of Enterococcus faecium exhibiting diverse susceptibility phenotypes to glycopeptides on clinical outcomes in patients with a bloodstream infection (BSI) through a prospective, multicenter, observational study. (asm.org)
- Nevertheless, they report, little is known about the pathogenesis of Enterococcus cecorum infection in broilers. (thepoultrysite.com)
- The broiler cycle investigated had a much better footpad scorethan the seven cycles before and four cycles after the Enterococcus cecorum infection at the same farm. (thepoultrysite.com)
- Bacteraemia and generalised infection appear to be important steps in the pathogenesis of Enterococcus cecorum infection in broilers, concluded Jung and Rautenschleim. (thepoultrysite.com)
- 2014. Comprehensive report of an Enterococcus cecorum infection in a broiler flock in Northern Germany. (thepoultrysite.com)
Endocarditis9
- Important clinical infections caused by Enterococcus include urinary tract infections (see Enterococcus faecalis), bacteremia, bacterial endocarditis, diverticulitis, meningitis, and spontaneous bacterial peritonitis. (wikipedia.org)
- We present the first documented case of human Enterococcus hirae infective endocarditis in the USA, representing only the fourth case worldwide. (medworm.com)
- Among them only two, that is, Enterococcus faecium and Enterococcus faecalis, are now being increasingly recognized to be involved in human infections such as bacteremia, endocarditis, urinary tract infections, and surgical site infections [ 1 , 2 ]. (hindawi.com)
- Is Once-Daily High-Dose Ceftriaxone plus Ampicillin an Alternative for Enterococcus faecalis Infective Endocarditis in Outpatient Parenteral Antibiotic Therapy Programs? (asm.org)
- Ceftriaxone administered as once-daily high-dose short infusion combined with ampicillin has been proposed for the treatment of Enterococcus faecalis infective endocarditis in outpatient parenteral antibiotic therapy programs (OPAT). (asm.org)
- Lack of this information could hinder the inclusion in OPAT of patients suffering from Enterococcus faecalis infective endocarditis treated with ampicillin plus. (asm.org)
- Enterococci are part of the normal human gut flora and can cause severe infections including urinary tract infections, gastrointestinal infections, catheter-related infections, and infective endocarditis (IE). (springer.com)
- Although an occasional success has been reported, 19, 20, 21, 22 the therapy of enterococcus endocarditis still remains a challenge. (annals.org)
- Enterococcus infections may occur in the urinary tract and in meningitis, diverticulitis, bacteremia and endocarditis infections with high mortality rate of ~61% in Portugal ( 2 ). (spandidos-publications.com)
Antibiotic Resistance1
- 2002). The Enterococci: Pathogenesis, Molecular Biology, and Antibiotic Resistance. (wikipedia.org)
Epidemiology1
- This Review discusses the factors involved in the changing epidemiology of enterococcal infections, with an emphasis on Enterococcus faecium as an emergent and challenging nosocomial problem. (nih.gov)
Pathogen6
- The small alarmone synthetase RelQ from the Gram-positive pathogen Enterococcus faecalis enzymatically regulates the levels of alarmone nucleotide (p)ppGpp, a key regulator of stress adaptation, pathogenicity, and antibiotic tolerance. (pnas.org)
- We show that the tetrameric small alarmone synthetase (SAS) RelQ from the Gram-positive pathogen Enterococcus faecalis is a sequence-specific RNA-binding protein. (pnas.org)
- Regarded as a gut commensal organism of animals and humans alike, with the potential to incidentally invade underlying tissue and being capable to withstand harsh environmental condition, enterococci have long been recognized as an important nosocomial pathogen. (nature.com)
- Enterococcus faecium has rapidly become a successful nosocomial pathogen. (rug.nl)
- Enterococcus cecorum is considered as an emerging pathogen in poultry and can cause substantial losses in broiler flocks, report researchers at the University of Veterinary Medicine Hannover in Germany. (thepoultrysite.com)
- Enterococcus faecium has become an important nosocomial pathogen, especially in immunocompromised patients, creating serious limitations in treatment options because of cumulative resistance to antimicrobial agents ( 1 ). (cdc.gov)
Clinical2
- The prevalence of enterococci harboring tetracycline- and vancomycin-resistance genes, as well as the enterococcal surface protein (esp) has mostly been determined in clinical settings, but their prevalence in tropical recreational waters remains largely unknown. (environmental-expert.com)
- Enterococci are used for improvement of the intestinal environment and have clinical benefits. (spandidos-publications.com)
Bacteremia1
- Factors associated with IE were studied retrospectively in a population-based cohort of patients with monomicrobial Enterococcus faecalis bacteremia (MEFsB). (springer.com)
Hirae3
Faecium and Enterococcus faecalis1
- They are Enterococcus faecium and Enterococcus faecalis. (reference.com)
Humans4
- Enterococcus faecalis, as the name implies, is found normally in the intestines of humans, animals and birds. (livestrong.com)
- Enterococci are considered to be part of normal gut microbiota in both humans and animals and capable to survive in a diverse range of harsh conditions. (hindawi.com)
- Our results indicate that there is a common source of enterococci for Mallards and humans. (diva-portal.org)
- Enterococci are natural inhabitants of the digestive tracts of humans and other mammals ( 16 ). (asm.org)
Escherichia2
- The reduction efficiency of Escherichia coli and intestinal enterococci in the sand filter is reported. (environmental-expert.com)
- EPA Home » Science Inventory » Enterococcus and Escherichia coli fecal source apportionment with microbial source tracking genetic markers - is it feasible? (epa.gov)
Detection of enterococci1
- Recently KWR presented an article about an innovative project: the rapid online detection of enterococci and of the total microbial activity in water. (environmental-expert.com)
Fecal5
- Rapid molecular identification of fecal origin-colonies growing on Enterococcus spp. (environmental-expert.com)
- But other fecal sources that contain enterococci and possibly human pathogens can be chronic or intermittent sources of both, making beach water quality management and remediation efforts more complex,' the investigators wrote. (news-medical.net)
- The US Environmental Protection Agency established water quality regulations based on enterococci as the indicator of fecal-borne pollution, to help manage water quality at estuarine and marine beaches. (news-medical.net)
- Our study pulls together the multiple fecal sources, the diverse environmental reservoirs, and the changeable environmental conditions to assess how these variables can all influence enterococci concentrations in a coastal setting,' said Dr. Jones. (news-medical.net)
- Here we mathematically derive and test a method that utilizes the ratios of fecal host-associated genetic markers and culture and molecular measurements of general fecal indicators to apportion enterococci, E. coli, and Bacteroidales. (epa.gov)
ATCC1
- Staphylococcus aureus (ATCC 6538), Enterococcus faecalis (ATCC 29212) and Candida albicans (ATCC 10231). (scielo.br)
Bacterial2
- New epidemiological evidence has shown that enterococci are major infectious agent in chronic bacterial prostatitis. (wikipedia.org)
- Enterococcus is used as a probiotic to improve the intestinal environment when treating bacterial diarrhea ( 3 ). (spandidos-publications.com)
Strain2
- Here we report that an Enterococcus faecium strain isolated from cow feces carries a BoNT-like toxin, designated BoNT/En. (diva-portal.org)
- Comparative genomic analysis determines that the E. faecium strain carrying BoNT/En is a commensal type and that the BoNT/En gene is located within a typical BoNT gene cluster on a 206 kb putatively conjugative plasmid. (diva-portal.org)
Organisms4
- Enterococci are facultative anaerobic organisms, i.e., they are capable of cellular respiration in both oxygen-rich and oxygen-poor environments. (wikipedia.org)
- Dr. Jones noted that enterococci are versatile organisms that thrive not only in the colon, but also in soil and in the sedimentary layers of lakes, rivers, and marine waters. (news-medical.net)
- In particular, culturable enterococci and E. coli, the organisms presently regulated in the United States and much of the world, decay at different rates compared to host-associated markers and as a result cannot be apportioned using this method. (epa.gov)
- However, limited data from a previous study suggest a similar decay rate between host-associated and QPCR-measured Enterococcus, E. coli and Bacteroidales genetic markers suggesting that apportionment may be possible for these organisms, however further work is needed to confirm. (epa.gov)
Infections caused2
- Vancomycin is an antibiotic that is often used to treat infections caused by enterococci. (medic8.com)
- Antibiotic use as growth promoters in animal feeding is considered one major factor responsible for the increase of infections caused by multiresistant enterococci. (unl.pt)
Colonization1
- Virulence factors of enterococci include the extracellular protein Esp and aggregation substances (Agg), both of which aid in colonization of the host. (nih.gov)
Among enterococci2
- Surprisingly through NCBI database analysis, there are some similarities observed in terms of their virulence determinants among enterococci. (hindawi.com)
- Among enterococci, Enterococcus faecalis occurs ubiquitously, with the highest incidence of human and animal infections. (asm.org)
Intestinal enterococci1
- Water quality--Detection and enumeration of intestinal enterococci in surface and waste water--Part 1: Miniaturized method (MPN) by inoculation in liquid medium. (atcc.org)
Firmicutes1
- Enterococcus é un xénero de bacterias do ácido láctico do filo Firmicutes . (wikipedia.org)
Pathogenesis1
- We demonstrate that the commensal bacterium Enterococcus faecalis contributes to the pathogenesis of anastomotic leak through its capacity to degrade collagen and to activate tissue matrix metalloproteinase 9 (MMP9) in host intestinal tissues. (sciencemag.org)
Genes1
- The current study was aimed to determine the prevalence of different virulence genes in Enterococcus faecalis and Enterococcus faecium . (hindawi.com)
Determinants1
- We investigated the prevalence, persistence and virulence determinants of enterococci populations in water samples collected over three rounds following an extreme flood event in a metropolitan river. (environmental-expert.com)
Microbiota1
- Enterococci take advantage of this reduction in REGIIIγ secretion to become the dominant members of the gut microbiota. (nih.gov)
Concentrations7
- Enterococci survive very harsh environments, including extremely alkaline pH (9.6) and salt concentrations. (wikipedia.org)
- Though they are not capable of forming spores, enterococci are tolerant of a wide range of environmental conditions: extreme temperature (5-65 °C), pH (4.5-10.0), and high sodium chloride concentrations. (wikipedia.org)
- We also found that ecosystem specific characteristics, such as freshwater sediment and freshwater transport to the estuary are important influences on enterococci concentrations in coastal recreational and shellfish harvest waters,' said Stephen Jones, Ph.D. Dr. Jones is Research Associate Professor, University of New Hampshire, and Associate Director, New Hampshire Sea Grant Program. (news-medical.net)
- In 2014, two of the town beaches had been flagged for intermittently exceeding state standards for concentrations of enterococci, and advisories had occasionally been posted warning the public that the waters might be unhealthy--bad publicity for a beach town. (news-medical.net)
- No other study has taken such an encompassing and robust approach towards addressing the issue of the factors that influence enterococci concentrations in coastal waters. (news-medical.net)
- Enterococcus Faecium (EF) is a probiotic and has been found when that dietary supplementation of EF can increase nutrient digestibility and decrease faecal NH3-N, H2S and volatile fatty acid (VFA) concentrations. (vitahound.com)
- The latter may have led to higher dust concentrations and thus airborne Enterococcus cecorum . (thepoultrysite.com)
20171
- Lebreton F, Manson AL, Saavedra JT, Straub TJ, Earl AM, Gilmore MS (2017) Tracing the Enterococci from Paleozoic origins to the hospital. (wikipedia.org)
Pathogenic1
- What makes Enterococcus faecalis pathogenic is less clear than with many other microorganisms. (livestrong.com)
Ampicillin-Susceptible1
- The most active β-lactams include the amino-penicillins (ampicillin) followed by penicillin, piperacillin, and carbapenems (imipenem is the most active, but meropenem and doripenem also have good activity in vitro against ampicillin-susceptible enterococci, although breakpoints have not been established). (psychiatryadvisor.com)
Facultatively anaerobic1
- Enterococci are facultatively anaerobic gram-positive cocci from the family Enterococcaceae . (psychiatryadvisor.com)
Antimicrobial Resistance2
- Canadian researchers have published a study assessing the antimicrobial resistance and virulence of genotypes of Enterococcus faecalis, taken from samples taken from a commercial pork processing plant. (pigprogress.net)
- The objective of the study was to assess the antimicrobial resistance and virulence genotypes of Enterococcus faecalis isolated from samples obtained from a commercial pork processing plant. (pigprogress.net)
Hospital2
- Enterococcus faecalis has been implicated in a wide variety of human infections and is a notorious problem in hospital-acquired infections. (livestrong.com)
- Because Enterococcus faecalis is normally found in the intestinal tract of people, it easily becomes a contamination problem in hospital and institutional settings. (livestrong.com)
Genome sequences1
- A database was built from 16 Enterococcus faecalis draft genome sequences to identify commonalities and polymorphisms in the location and content of CRISPR loci. (asm.org)