Entamoeba histolytica
Entamoeba
Entamoebiasis
Dysentery, Amebic
Liver Abscess, Amebic
Trophozoites
Amebicides
Amebiasis
Intestinal Diseases, Parasitic
Protozoan Infections
Feces
Giardia lamblia
Antigens, Protozoan
Cysteine Proteases
Lectins
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
Dientamoeba
Blastocystis hominis
A species of parasitic protozoa found in the intestines of humans and other primates. It was classified as a yeast in 1912. Over the years, questions arose about this designation. In 1967, many physiological and morphological B. hominis characteristics were reported that fit a protozoan classification. Since that time, other papers have corroborated this work and the organism is now recognized as a protozoan parasite of humans causing intestinal disease with potentially disabling symptoms.
Gerbillinae
Parasites
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Metronidazole
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
Giardiasis
Giardia
Galactose
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Protozoan Vaccines
Galectins
A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.
Liver Abscess
Amino Acid Sequence
Iodoquinol
Serine O-Acetyltransferase
Host-Parasite Interactions
Pyruvate Synthase
Trichomonas
Dysentery
Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.
Access to Information
Gastroenterology
Bibliometrics
Hsp60 is targeted to a cryptic mitochondrion-derived organelle ("crypton") in the microaerophilic protozoan parasite Entamoeba histolytica. (1/861)
Entamoeba histolytica is a microaerophilic protozoan parasite in which neither mitochondria nor mitochondrion-derived organelles have been previously observed. Recently, a segment of an E. histolytica gene was identified that encoded a protein similar to the mitochondrial 60-kDa heat shock protein (Hsp60 or chaperonin 60), which refolds nuclear-encoded proteins after passage through organellar membranes. The possible function and localization of the amebic Hsp60 were explored here. Like Hsp60 of mitochondria, amebic Hsp60 RNA and protein were both strongly induced by incubating parasites at 42 degreesC. 5' and 3' rapid amplifications of cDNA ends were used to obtain the entire E. histolytica hsp60 coding region, which predicted a 536-amino-acid Hsp60. The E. histolytica hsp60 gene protected from heat shock Escherichia coli groEL mutants, demonstrating the chaperonin function of the amebic Hsp60. The E. histolytica Hsp60, which lacked characteristic carboxy-terminal Gly-Met repeats, had a 21-amino-acid amino-terminal, organelle-targeting presequence that was cleaved in vivo. This presequence was necessary to target Hsp60 to one (and occasionally two or three) short, cylindrical organelle(s). In contrast, amebic alcohol dehydrogenase 1 and ferredoxin, which are bacteria-like enzymes, were diffusely distributed throughout the cytosol. We suggest that the Hsp60-associated, mitochondrion-derived organelle identified here be named "crypton," as its structure was previously hidden and its function is still cryptic. (+info)Prevalence of intestinal parasite infections with special reference to Entamoeba histolytica on the island of Bioko (Equatorial Guinea). (2/861)
The prevalence of intestinal parasitic infections was assessed (1993 through 1995) among two different groups of persons on the island of Bioko, Equatorial Guinea. In the first group, parasitologic examinations were performed on stool specimens from a household-based sample of 557 dwellers from the rural area of the island. In the second group, 1,633 inpatients and outpatients at the General Hospital of Malabo (the capital of the country) were studied. All age groups were represented in both groups. The average prevalence of the most common protozoan and helminthic intestinal infections in rural and urban areas, respectively, was as follows: Entamoeba histolytica/E. dispar (14.9% and 32.7%, respectively), Giardia lamblia (7.2% and 8.6%), Ascaris lumbricoides (45.8% and 31.4%), and Trichuris trichiura (25.7% and 36.4%). Seventy-nine sera from patients with amebic liver abscess (suspected by ultrasonography) were studied by an immunohemagglutination assay, with 44 (56%) showing anti-E. histolytica titers > or = 1:32. Of these 79 sera, 71 were studied by an enzyme immunoassay, 86% of which were positive with titers > or = 1:64. This study showed that parasitic infections in Equatorial Guinea represent a major health problem. (+info)Characterization of YS-27, an axenic Korean strain of Entamoeba histolytica. (3/861)
Characterization of YS-27, an axenic Entamoeba strain, was performed by three different laboratory methods. Zymodeme analysis using starch gel electrophoresis and PCR with species-specific primers showed that YS-27 is a pathogenic Entamoeba which belongs to the group II zymodeme. Pathogenicity of YS-27 was further confirmed by observing the formation of liver abscess in Mongolian gerbils. These results showed that YS-27 is E. hisolytica. (+info)The TATA-box binding protein of Entamoeba histolytica: cloning of the gene and location of the protein by immunofluorescence and confocal microscopy. (4/861)
A 309 bp DNA fragment from Entamoeba histolytica was amplified by PCR using primers derived from the Acanthamoeba castellanii consensus TATA-box binding protein amino acid sequence. The amplified fragment was used to isolate cDNA and genomic DNA clones containing an ORF encoding the complete E. histolytica TATA-box binding protein (Ehtbp, 702 bp, 234 aa, molecular mass 26 kDa). The EhTBP functional domain showed 55% sequence identity to that of Homo sapiens, 54% to A. castellanii and 37% to Plasmodium falciparum TBPs. In Southern blot experiments we detected a single Ehtbp band, which was transcribed as a 1.3 kb mRNA containing a 420 nt 5' untranslated region. However, the probe hybridized with the 0.8 and 1.5 Mb chromosomes, suggesting that this sequence is diploid. In situ PCR assays showed two signals in 95% of trophozoites, one located in the nucleus and another in EhkO, the novel DNA-containing organelle recently reported. The recombinant E. histolytica TATA-box binding protein was expressed in Escherichia coli. Antibodies against it recognized two proteins of 26 and 29 kDa in E. histolytica nuclear extracts. Confocal microscopy immunofluorescence analysis located the protein in both the nucleus and EhkO. (+info)Preparation of recombinant human monoclonal antibody Fab fragments specific for Entamoeba histolytica. (5/861)
Genes coding for human antibody Fab fragments specific for Entamoeba histolytica were cloned and expressed in Escherichia coli. Lymphocytes were separated from the peripheral blood of a patient with an amebic liver abscess. Poly(A)+ RNA was isolated from the lymphocytes, and then genes coding for the light chain and Fd region of the heavy chain were amplified by a reverse transcriptase PCR. The amplified DNA fragments were ligated with a plasmid vector and were introduced into Escherichia coli. Three thousand colonies were screened for the production of antibodies to E. histolytica HM-1:IMSS by an indirect fluorescence-antibody (IFA) test. Lysates from five Escherichia coli clones were positive. Analysis of the DNA sequences of the five clones showed that three of the five heavy-chain sequences and four of the five light-chain sequences differed from each other. When the reactivities of the Escherichia coli lysates to nine reference strains of E. histolytica were examined by the IFA test, three Fab fragments with different DNA sequences were found to react with all nine strains and another Fab fragment was found to react with seven strains. None of the four human monoclonal antibody Fab fragments reacted with Entamoeba dispar reference strains or with other enteric protozoan parasites. These results indicate that the bacterial expression system reported here is effective for the production of human monoclonal antibodies specific for E. histolytica. The recombinant human monoclonal antibody Fab fragments may be applicable for distinguishing E. histolytica from E. dispar and for use in the serodiagnosis of amebiasis. (+info)Down regulation of Entamoeba histolytica virulence by monoxenic cultivation with Escherichia coli O55 is related to a decrease in expression of the light (35-kilodalton) subunit of the Gal/GalNAc lectin. (6/861)
Entamoeba histolytica virulence is related to a number of amebic components (lectins, cysteine proteinases, and amebapore) and host factors, such as intestinal bacterial flora. Trophozoites are selective in their interactions with bacteria, and the parasite recognition of glycoconjugates plays an important role in amebic virulence. Long-term monoxenic cultivation of pathogenic E. histolytica trophozoites, strains HK-9 or HM-1:IMSS, with Escherichia coli serotype O55, which binds strongly to the Gal/GalNAc amebic lectin, markedly reduced the trophozoites' adherence and cytopathic activity on cell monolayers of baby hamster kidney (BHK) cells. Specific probes prepared from E. histolytica lectin genes as well as antibodies directed against the light (35-kDa) and heavy (170-kDa) subunits of the Gal/GalNAc lectin revealed a decrease in the transcription and expression of the light subunit in trophozoites grown monoxenically with E. coli O55. This effect was not observed when E. histolytica was grown with E. coli 346, a mannose-binding type I pilated bacteria. Our results suggest that the light subunit of the amebic lectin is involved in the modulation of parasite adherence and cytopathic activity. (+info)Chitinase secretion by encysting Entamoeba invadens and transfected Entamoeba histolytica trophozoites: localization of secretory vesicles, endoplasmic reticulum, and Golgi apparatus. (7/861)
Entamoeba histolytica, the protozoan parasite that phagocytoses bacteria and host cells, has a vesicle/vacuole-filled cytosol like that of macrophages. In contrast, the infectious cyst form has four nuclei and a chitin wall. Here, anti-chitinase antibodies identified hundreds of small secretory vesicles in encysting E. invadens parasites and in E. histolytica trophozoites overexpressing chitinase under an actin gene promoter. Abundant small secretory vesicles were also identified with antibodies to the surface antigen Ariel and with a fluorescent substrate of cysteine proteinases. Removal of an N-terminal signal sequence directed chitinase to the cytosol. Addition of a C-terminal KDEL peptide, identified on amebic BiP, retained chitinase in a putative endoplasmic reticulum, which was composed of a few vesicles of mixed sizes. A putative Golgi apparatus, which was Brefeldin A sensitive and composed of a few large, perinuclear vesicles, was identified with antibodies to ADP-ribosylating factor and to epsilon-COP. We conclude that the amebic secretory pathway is similar to those of other eukaryotic cells, even if its appearance is somewhat different. (+info)Intestinal mucins in colonization and host defense against pathogens. (8/861)
Intestinal mucins are key components of the first line of host defense against intestinal pathogens. These large glycoconjugates secreted by specialized exocrine goblet cells form viscous gels that trap microorganisms and irritants and limit their diffusion to the intestinal epithelium. Moreover, they allow for colonization by indigenous bacterial flora that prevents attachment of pathogenic microbes. The interaction between microbes and mucins involves mucin carbohydrate side chains and microbial adhesin molecules. Certain microorganisms and disease states may alter mucin biochemistry or expression. Although these alterations most likely contribute to disease processes, the full impact of these phenomena are still unclear. The development of mucin-secreting cell lines has facilitated the study of mucin biology and aided our understanding of mucin-microbial interactions. (+info)
Category:Entamoeba histolytica - Wikimedia Commons
Transcriptomic comparison of two Entamoeba histolytica strains with defined virulence phenotypes identifies new virulence...
Mitosomes of Entamoeba histolytica are abundant mitochondrion-related remnant organelles that lack a detectable organellar...
Cell polarization and adhesion in a motile pathogenic protozoan: role and fate of the Entamoeba histolytica Gal/GalNAc lectin •...
Investigation on Entamoeba histolytica infection in diarrhea patients from general hospitals in Shanghai City] | GHDx
Genome Sequencing of Clinically Important Strains of Entamoeba Histolytica | J. Craig Venter Institute
Diversity of clinical isolates of Entamoeba histolytica in Japan<...
PLOS Neglected Tropical Diseases: Increased Risk for Entamoeba histolytica Infection and Invasive Amebiasis in HIV Seropositive...
Entamoeba histolytica Cysteine Proteinases Disrupt the Polymeric Structure of Colonic Mucin and Alter Its Protective Function |...
Nitro BlueTetrazolium Chloride and Phagocytic Activity for Entamoeba Histolytica
| Al-Mustansiriyah Journal of...
Structural determinants of ubiquitin conjugation in entamoeba histolytica<...
Trophozoites of Entamoeba histolytica express a CD59-like molecule in human colon - Semantic Scholar
Point-of-Care Diagnostic Test for Entamoeba histolytica Cysts - Joel Herbein
Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human...
Identification of dihydropyrimidine dehydrogenase as a virulence factor essential for the survival of Entamoeba histolytica in...
Medical Chemical Corporation: Para-site
Entamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase Family
Entamoeba coli - Wikipedia
Entamoeba histolytica
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Entamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo Library
Molecules | Free Full-Text | Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican...
REGULATION OF THE LIPID RAFT LOCALIZATION OF THE GAL/GALNAC LECTIN, AN by Amanda Goldston
Studies on the Pathogenicity of Various Strains of Entamoeba Histolytica after Prolonged Cultivation, with Observations on...
Entamoeba histolytica Schaudinn ATCC ® 30015™
Entamoeba histolytica Schaudinn ATCC ® 30015™
The Cultivation of Endamoeba histolytica by Maurice E. Callender
The genome of the protist parasite Entamoeba histolytica. : CRC 1182
Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite...
The American Journal of Tropical Medicine and Hygiene | Induced Division Synchrony in Entamoeba Histolytica
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RIDASCREEN® Entamoeba histolytica IgG (en) - Clinical Diagnostics
Amebiasis histolytica Antibody
References - Biology Online
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Iraqi Academic Scientific Journals - IASJ
Antigens, Tumor-Associated, Carbohydrate | REACH
Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts - Full Text View - ClinicalTrials.gov
Entamoeba histolytica: The Cause of Amoebiasis (November 22, 2017) | Global Water Pathogen Project
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In silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species | Semantic Scholar
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The genome and transcriptome of the enteric parasite Entamoeba invadens , a model for encystation | Genome Biology | Full Text
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Value of microscopy in the diagnosis of dysentery associated with invasive Entamoeba histolytica. | Journal of Clinical...
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Amebiasis
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Protozoa
"Microscopy of Entamoeba histolytica". msu.edu. Retrieved 2016-08-21. Lehman, Don. "Diagnostic parasitology". University of ... Entamoeba histolytica) Sporozoans, or Sporozoa (parasitic, spore-producing cells, whose adult form lacks organs of motility, e. ...
Amoeba
... and Dmc1 is expressed in Entamoeba histolytica. The purified Dmc1 from E. histolytica forms presynaptic filaments and catalyses ... "Microscopy of Entamoeba histolytica". msu.edu. Archived from the original on 5 October 2016. Retrieved 21 August 2016. "Arcella ... Some amoebae can infect other organisms pathogenically, causing disease: Entamoeba histolytica is the cause of amoebiasis, or ... These processes are central to meiotic recombination, suggesting that E. histolytica undergoes meiosis. Studies of Entamoeba ...
Diarrhea
Dysentery is a symptom of, among others, Shigella, Entamoeba histolytica, and Salmonella. Diarrheal disease may have a negative ... Parasites, particularly protozoa e.g., Cryptosporidium spp., Giardia spp., Entamoeba histolytica, Blastocystis spp., Cyclospora ...
Trypanothione
It is unique to the Kinetoplastida and not found in other parasitic protozoa such as Entamoeba histolytica. Since this thiol is ... Ariyanayagam MR, Fairlamb AH (September 1999). "Entamoeba histolytica lacks trypanothione metabolism". Mol. Biochem. Parasitol ...
Blastocystosis
"Secretory Hormones of Entamoeba histolytica". Secretory hormones of Entamoeba histolytica. Ciba Found. Symp. Novartis ... 1983). "Entamoeba histolytica causes intestinal secretion: role of serotonin". Science. 221 (4612): 762-4. Bibcode:1983Sci... ... Other secretory mechanism: A study of a different protozoan which produces similar symptoms, Entamoeba histolytica, found that ... Serum levels of serotonin have been found to be elevated in patients with Entamoeba histolytica. Diagnosis is performed by ...
Serotonin
"Secretory Hormones of Entamoeba histolytica". Secretory hormones of Entamoeba histolytica. Ciba Foundation Symposium. Novartis ... The gastrointestinal parasite Entamoeba histolytica secretes serotonin, causing a sustained secretory diarrhea in some people. ... August 1983). "Entamoeba histolytica causes intestinal secretion: role of serotonin". Science. 221 (4612): 762-4. Bibcode: ... Acharya DP, Sen MR, Sen PC (August 1989). "Effect of exogenous 5-hydroxytryptamine on pathogenicity of Entamoeba histolytica in ...
Denis G. Lillie
doi:10.1016/S0140-6736(01)38919-5. Lillie, D.G.; Shepheard, S. (1917). "A Report on the Treatment of Entamoeba histolytica " ... Lillie, D.G.; Shepheard, S. (1917). "A Report on the Treatment of Entamoeba histolytica "Carriers" with Emetine Bismuth Iodide ... doi:10.1016/S0140-6736(01)51966-2. Shepheard, S.; Lillie, D.G. (1918). "Persistent Carriers of Entamoeba histolytica. Treatment ... Shepheard, S.; Lillie, D.G. (1918). "Persistent Carriers of Entamoeba histolytica. Treatment with Chaparro Amargosa and ...
Traveler's diarrhea
Entamoeba histolytica 0-5% Cryptosporidium spp. 0-20% Cyclospora cayetanensis ? Rotavirus 0-36% ...
Lung abscess
Parasites: Entamoeba histolytica. Diagnosis[edit]. Imaging studies[edit]. Lung abscesses are often on one side and single ...
Amoebic brain abscess
Shah, AA; Shaikh, H; Karim, M (February 1994). "Amoebic brain abscess: a rare but serious complication of Entamoeba histolytica ... It may be caused by Entamoeba histolytica. Primary amoebic meningoencephalitis Granulomatous amoebic encephalitis Naegleria ...
Pyruvate oxidase (CoA-acetylating)
Reeves RE, Warren LG, Susskind B, Lo HS (1977). "An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. ... Takeuchi T, Weinbach EC, Diamond LS (1975). "Pyruvate oxidase (CoA acetylating) in Entamoeba histolytica". Biochem. Biophys. ...
Organelle
Fahey RC, Newton GL, Arrick B, Overdank-Bogart T, Aley SB (April 1984). "Entamoeba histolytica: a eukaryote without glutathione ...
Substance P
Entamoeba histolytica is a unicellular parasitic protozoan that infects the lower gastrointestinal tract of humans. The ... McGowan K, Kane A, Asarkof N, Wicks J, Guerina V, Kellum J, Baron S, Gintzler AR, Donowitz M (Aug 1983). "Entamoeba histolytica ... McGowan K, Guerina V, Wicks J, Donowitz M (1985). "Chapter 8: Secretory Hormones of Entamoeba histolytica". In D. Evered, J. ...
Histolysain
Entamoeba histolytica cysteine proteinase, amebapain, Entamoeba histolytica cysteine protease, Entamoeba histolytica neutral ... Entamoeba histolytica. Lushbaugh WB, Hofbauer AF, Pittman FE (June 1985). "Entamoeba histolytica: purification of cathepsin B ... the major cysteine proteinase of Entamoeba histolytica". The Biochemical Journal. 250 (3): 903-9. doi:10.1042/bj2500903. PMC ...
William A. Petri
... and human immune response to Entamoeba histolytica and strain-associated differences in E. histolytica virulence. He leads the ... The Genome Of The Protist Parasite Entamoeba histolytica. Loftus, B; Anderson, I; Davies, R et al. Nature 433: 865-868, 2005 ... 1994 Rat And Human Colonic Mucins Bind to and Inhibit Adherence Lectin of Entamoeba-histolytica. Chadee, K; Petri, Wa; Innes, ... 2003 Isolation of the Galactose-Binding Lectin That Mediates the in vitro Adherence of Entamoeba histolytica. Petri, WA; Smith ...
Srinivasa Ramanujan
Gunn, J. W. C. and Savage, B. (1919). "Report on the treatment of Entamoeba histolytica infections". Journal of the Royal Army ...
G protein
Bosch DE, Siderovski DP (March 2013). "G protein signaling in the parasite Entamoeba histolytica". Experimental & Molecular ...
Acetate kinase (diphosphate)
A fourth pyrophosphate-dependent kinase from Entamoeba histolytica". Biochem. Biophys. Res. Commun. 66 (4): 1389-95. doi: ...
Unicellular organism
Entamoeba histolytica is the cause of amebic dysentery. Entamoeba histolytica appears to be capable of meiosis. Unicellular ... "Entamoeba histolytica Dmc1 Catalyzes Homologous DNA Pairing and Strand Exchange That Is Stimulated by Calcium and Hop2-Mnd1". ...
Refugee health
Approximately 480 million people are infected with Entamoeba histolytica. At least 500 million carry Trichuris. At present, 200 ...
Housefly
Parasites carried include cysts of protozoa, e.g. Entamoeba histolytica and Giardia lamblia and eggs of helminths; e.g., ...
Phosphoglycerate kinase (GTP)
Reeves RE, South DJ (1974). "Phosphoglycerate kinase (GTP). An enzyme from Entamoeba histolytica selective for guanine ...
Digestion
In humans, Entamoeba histolytica can phagocytose red blood cells. To aid in the digestion of their food, animals evolved organs ... Boettner, D.R.; Huston, C.D.; Linford, A.S.; Buss, S.N.; Houpt, E.; Sherman, N.E.; Petri, W.A. (2008). "Entamoeba histolytica ...
Nitazoxanide
It is also an effective treatment option for infections caused by other protozoa and helminths (e.g., Entamoeba histolytica, ... Entamoeba histolytica, G. lamblia and Trichomonas vaginalis [13] White CA (2004). "Nitazoxanide: a new broad spectrum ...
Cutaneous amoebiasis
It can be caused by Acanthamoeba or Entamoeba histolytica. When associated with Acanthamoeba, it is also known as "cutaneous ...
List of sequenced protist genomes
February 2005). "The genome of the protist parasite Entamoeba histolytica" (PDF). Nature. 433 (7028): 865-8. Bibcode:2005Natur. ...
Trichomonas vaginalis
Unlike other parasitic protozoa (Giardia lamblia, Entamoeba histolytica etc.), Trichomonas vaginalis exists in only one ...
Acetate-CoA ligase (ADP-forming)
Reeves RE, Warren LG, Susskind B, Lo HS (1977). "An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. ...
Saliva testing
El Hamshary EM, Arafa WA (December 2004). "Detection of IgA anti-Entamoeba histolytica in the patients' saliva". J Egypt Soc ... A 2010 study found that saliva-based detection of the parasite Entamoeba histolytica was superior to existing fecal detection ... August 2010). "Diagnosis of amebic liver abscess and amebic colitis by detection of Entamoeba histolytica DNA in blood, urine, ... In 2004 El Hamshary and Arafa found that salivary anti-E. histolytica IgA concentration had "predictive diagnostic value of ...
Toxic megacolon
It can also be caused by Entamoeba histolytica and Shigella. It may also be caused by the use of loperamide. Abdominal pain ...
Substance P
Entamoeba histolytica is a unicellular parasitic protozoan that infects the lower gastrointestinal tract of humans. The ... McGowan K, Kane A, Asarkof N, Wicks J, Guerina V, Kellum J, Baron S, Gintzler AR, Donowitz M (Aug 1983). "Entamoeba histolytica ... McGowan K, Guerina V, Wicks J, Donowitz M (1985). "Chapter 8: Secretory Hormones of Entamoeba histolytica". In D. Evered, J. ...
Mikroorganismid - Vikipeedia
Parasiitne mikroorganism on näiteks peamiselt troopilises kliimas leviv düsenteeria-siseamööb (Entamoeba histolytica), mis ...
Category:Protista - Simple English Wikipedia, the free encyclopedia
Entamoeba histolytica. *Euglena. *Euglenozoa. *Extremophile. F. *Flagellate. *Flagellum. *Foraminifera. G. *Great Oxygenation ...
Hepatit - Vikipedi
Entamoeba histolytica[45]. *Cryptosporidium[46]. *Isospora[47][48]. *Leishmania[45]. *Plasmodium[49] ...
Innate immune system
Entamoeba histolytica. *Giardia lamblia. yes. yes. no Extracellular fungi. *Candida. *Histoplasma. *Cryptococcus ...
Srinivasa Ramanujan
Gunn, J. W. C., & SAVAGE, B. (1919). Report on the Treatment of Entamoeba Histolytica Infections. Journal of the Royal Army ...
Doris Mackinnon
"Persons who have never been out of Great Britain as Carriers of Entamoeba histolytica". Annals of Tropical Medicine and ... "A Preliminary Statement on the Treatment of Entamoeba histolytica Infections by " Alcresta Ipecac."". Annals of Tropical ...
Eukaryoty - Wikipédia
Entamoeba histolytica a ďalšie. Poznáme i mnohé parazitické rastliny, konkrétne jednobunkové riasy rodu Prototheca, ale aj ...
COVID-19 - Vikipedi
Entamoeba histolytica. *Visseral Leishmaniasis (Kala-Azar). *Kutaneöz Leishmaniasis. *Şistozomiyaz (Üriner). *Sıtma. * ...
Usuario:AVBOT/Reversiones humanas/2009/10/27, la enciclopedia libre
Entamoeba histolytica (diff). *Reproducción (diff). *Nacionalismo (diff). *García (diff). *John Lennon (diff) ...
Housefly
Parasites carried include cysts of protozoa, e.g. Entamoeba histolytica and Giardia lamblia and eggs of helminths; e.g., ...
Kategoria:Amoebozoa, entziklopedia askea.
Entamoeba. *Entamoeba histolytica. "https://eu.wikipedia.org/w/index.php?title=Kategoria:Amoebozoa&oldid=4651245"(e)tik ...
Infection
Common fecal-oral transmitted pathogens include Vibrio cholerae, Giardia species, rotaviruses, Entameba histolytica, ...
Protozoa
"Microscopy of Entamoeba histolytica". msu.edu. Pristupljeno 21. 8. 2016.. *^ Lehman, Don. "Diagnostic parasitology". University ... Entamoeba histolytica (Amoebozoa) Voda, hrana Acanthamoeba keratitis Acanthamoeba (Amoebozoa) Voda, kontaminiranu kontakt ... Trofozoiti patogene amebna dizenterija "Entamoeba histolytica s unesenom ljudskom crvenom krvnom ćelijom s (tamni krugovi) ... Amoebae ili Sarcodina (ćelije koje se kreću širenjem pseudopodija ili lamelipodija, npr., Entamoeba histolytica) ...
Amoebic liver abscess
It is the involvement of liver tissue by trophozoites of the organism Entamoeba histolytica and of is abscess due to necrosis. ... The treatment of invasive amoebiasis should be directed to all sites where E. histolytica may be present. Hence the ideal ... This amoebicide acts directly on the trophozoites of E. Histolytica. Studies showed that because of very high concentration in ... The high concentration in the liver parenchyma and the lung allows the drug to act upon E. Histolytica in cases of amoebic ...
Wastewater
Protozoa (for example Entamoeba histolytica, Giardia lamblia, Cryptosporidium parvum) and. *Parasites such as helminths and ...
Gastroenteraytis, ang malayang ensiklopedya
... ngunit ang mga uri na Entamoeba histolytica at Cryptosporidium ay kasama rin.[16] Bilang isang grupo, ang mga bagay na ito ay ... Sa mga may Giardia o Entamoeba histolytica na uri, ang paggamot gamit angtinidazole ay inirerekomenda at mas mahusay sa ...
Mitozom - Wikipedie
Poprvé byl popsán u střevního parazita Entamoeba histolytica.[1][3] Dále byl identifikován např. v několika mikrosporidiích[4][ ... 2000). The Entamoeba histolytica mitochondrion-derived organelle (crypton) contains double-stranded DNA and appears to be bound ... Leon-Avila, G. & Tovar, J. (2004). Mitosomes of Entamoeba histolytica are abundant mitochondrion-related remnant organelles ... a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica. Molecular Microbiology 32, 1013 ...
Corticosteroid
... amebic colitis is associated with high case fatality and can occur in patients infected with the parasite Entamoeba histolytica ...
Cold chain
Entamoeba histolytica. *Giardia. *Trichinella. .mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw- ...
G protein
Bosch DE, Siderovski DP (March 2013). "G protein signaling in the parasite Entamoeba histolytica". Experimental & Molecular ...
Basal - Simple English Wikipedia, the free encyclopedia
... the absence of mitochondria in the anaerobic protist Entamoeba histolytica is a result of their secondary loss. ...
Amoeba, ang malayang ensiklopedya
Ang pangunahing kahalagahan nito ay dapat itong maipagkaiba mula sa entamoeba histolytica, na sanhi ng disenteryang amebiko at ... Ang entamoeba coli ay maaaring nasa mga tae, subalit hindi nakakapagbigay ng suliranin. ...
Digestion
In humans, Entamoeba histolytica can phagocytose red blood cells.[12]. Specialised organs and behaviours. To aid in the ... "Entamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase Family". PLoS ...
Mouth ulcer
Entamoeba histolytica, a parasitic protozoan, is sometimes known to cause mouth ulcers through formation of cysts.[citation ...
Metronidazole
E. histolytica[edit]. Entamoeba histolytica invasive amebiasis is treated with metronidazole for eradication, in combination ...
நுண்ணுயிர் காப்புக்கூடு - தமிழ் விக்கிப்பீடியா
அமீபாவின் (Entamoeba histolytica) காப்புக் கூடு நிலை. கடல் உயிரியான ஆர்த்தீமியாவின் காப்புக் கூடு (Artemia salina) ...
Gastroenteritis, entziklopedia askea.
Entamoeba histolytica eta Cryptosporidium generoko protozoo parasitoek umeengan agertu diren kasuen %10a eragin dituzte. ...
Mikroorganismid - Vikipeedia, vaba entsüklopeedia
Parasiitne mikroorganism on näiteks peamiselt troopilises kliimas leviv düsenteeria-siseamööb (Entamoeba histolytica), mis ...
Category:Entamoeba histolytica - Wikimedia Commons
Entamoeba histolytica (es); Entamoeba histolytica (hu); Entamoeba histolytica (eu); Entamoeba histolytica (ast); Entamoeba ... Entamoeba histolytica (da); Entamoeba histolytica (tr); 溶組織內阿米巴 (zh-hk); Entamoeba histolytica (sv); Entamoeba histolytica (uk ... entamoeba histolytica (ckb); Entamoeba histolytica (gl); متحولة حالة للنسج (ar); 溶组织内阿米巴 (zh-hans); Entamoeba histolytica (he) ... Entamoeba histolytica (ru); Entamoeba histolytica (fi); Entamoeba hystolitica (it); متمورة حالة للنسج, اميبا طفيلية, Entamoeba ...
Entamoeba histolytica | protozoan | Britannica.com
... is caused by the protozoan Entamoeba histolytica. This form of dysentery, which traditionally occurs in the tropics, is usually ... Other articles where Entamoeba histolytica is discussed: dysentery: … ... In Entamoeba. …of many vertebrates, including humans; E. histolytica is the cause of human amebic dysentery. The cell nucleus, ... dysentery-causing Entamoeba histolytica. These protozoans cells may be spherical or irregular in shape; the pellicle (or ...
Entamoeba histolytica
... is an anaerobic parasitic protozoan, part of the genus Entamoeba, which predominantly infects humans and ... "The genome of the protist parasite Entamoeba histolytica.". Loftus B.J., Anderson I., Davies R., Alsmark U.C., Samuelson J., ... Entamoeba histolytica (strain HM-1:IMSS) is the first human amoeba to have its genome sequenced, assembled and analyzed. ... The reference proteome of Entamoeba histolytica is derived from the genome sequence published in 2005. The genome is 24Mb in ...
Entamoeba histolytica - Wikipedia
"Entamoeba histolytica". cdc.gov. Centers for Disease Control. Retrieved 24 October 2017. "Entamoeba histolytica". Centers for ... Entamoeba histolytica image library Entamoeba histolytica - Centers for Disease Control and Prevention CDC DPDx Parasitology ... Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. Predominantly infecting humans and ... Amoebic intestinal ulcer caused by E. histolytica Trophozoites of E. histolytica with ingested erythrocytes E. histolytica cyst ...
Entamoeba histolytica
... , E. histolytica, Amebiasis, Amoebiasis, Amebic Dysentery, Ameboma, Amoeba Histolytica Dysentery. ... Entamoeba histolytica. search Entamoeba histolytica, E. histolytica, Amebiasis, Amoebiasis, Amebic Dysentery, Ameboma, Amoeba ... Precaution: Microscopy alone does not distinguish E histolytica from the benign E. dispar ... Entamoeba histolytica by stool PCR (preferred). *Entamoeba histolytica by stool antigen testing. *Test Sensitivity: 87% ...
Entamoeba histolytica
... , E. histolytica, Amebiasis, Amoebiasis, Amebic Dysentery, Ameboma, Amoeba Histolytica Dysentery. ... entameba histolytica, histolytica entamoeba, ENTAMOEBA HISTOLYTICA, Eh - Entamoeba histolytica, Entamoeba histolytica (organism ... Entamoeba histolytica. Spanish. Entamoeba histolytica, Entameba histolytica, Entamoeba histolytica (organismo), Endamoeba ... Entamoeba histolytica, Eh - Entameba histolytica, Endamoeba histolyticas, histolytica, Endamoeba, histolytica, Entamoeba, ...
Entamoeba histolytica Schaudinn ATCC ® 30015™
Entamoeba histolytica ATCC ® 30015™ Designation: HK-9 Isolation: Colonic biopsy from adult human male with amebic dysentery, ... Techniques of axenic cultivation of Entamoeba histolytica Schaudinn, 1903 and E. histolytica-like amebae. J. Parasitol. 54: ... Entamoeba histolytica Schaudinn (ATCC® 30015™) Strain Designations: HK-9 / Depositor: LS Diamond / Biosafety Level: 2 ... Attachment of Entamoeba histolytica to glass in a defined maintenance medium: Specific requirement for cysteine and ascorbic ...
Entamoeba histolytica: Gene Expression Analysis of Cells Invading Tissues
... Helen C. Fernandes,1 Ana F. Costa,1 Michelle A. R. ... L. A. Baxt and U. Singh, "New insights into Entamoeba histolytica pathogenesis," Current Opinion in Infectious Diseases, vol. ... C. He, G. P. Nora, E. L. Schneider et al., "A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive ... G. León-Avila, M. Hernández, M. Camacho-Nuez et al., "Entamoeba histolytica up-regulates the CDC48-like protein, an family ...
Amebiasis: Infection and Disease by Entamoeba Histolytica - 1st Editio
Tissue destruction and invasion by Entamoeba histolytica
Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source of morbidity and mortality in the ... Tissue destruction and invasion by Entamoeba histolytica Trends Parasitol. 2011 Jun;27(6):254-63. doi: 10.1016/j.pt.2011.02.006 ... Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source of morbidity and mortality in the ...
LINEs and SINE-like elements of the protist Entamoeba histolytica. - PubMed - NCBI
Entamoeba histolytica HM-1:IMSS gcontig 1104750507432, whole genome sh - Nucleotide - NCBI
Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development
Entamoeba dispar. The Entamoeba dispar species is morphologically similar to E. histolytica, but due to antigenic and genetic ... "Mucosal Immunity to Asymptomatic Entamoeba histolytica and Entamoeba dispar Infection Is Associated with a Peak Intestinal Anti ... Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development. Micaella Kantor,1 Anarella ... Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality ...
Medline ®
Abstract for Reference
42 of 'Intestinal Entamoeba histolytica amebiasis'
Evaluation of a new single-tube multiprobe real-time PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar. ... A single-tube multiprobe real-time PCR assay for simultaneous detection of Entamoeba histolytica and Entamoeba dispar was ... A total of 51 E. histolytica and 39 E. dispar positive samples was detected by the multiprobe real-time PCR compared to 39 and ... The detection rate of Entamoeba species for the multiprobe real-time PCR assays was significantly higher than the nested PCR ( ...
Thiol proteinase expression and pathogenicity of Entamoeba histolytica
... neutral thiol proteinase has been shown to correlate with the potential of clinical isolates of Entamoeba histolytica to ... Thiol proteinase expression and pathogenicity of Entamoeba histolytica J Clin Microbiol. 1989 Dec;27(12):2772-7. doi: 10.1128/ ... neutral thiol proteinase has been shown to correlate with the potential of clinical isolates of Entamoeba histolytica to ...
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica | PNAS
The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa ... Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica. E Tannich, F Ebert, and R D Horstmann ... Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica ... Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica ...
Possible Function of Entamoeba histolytica in Creation Model
| Answers in Genesis
There is a need for parasites such as Entamoeba histolytica to be addressed from a biblical perspective that may include their ... Ecology of Entamoeba histolytica Amoebas may be parasitic (for example, E. histolytica), commensal, or free living. Eight ... A redescription of Entamoeba histolytica Schaudinn, 1903 (emended Walker, 1911) separating it from Entamoeba dispar Brumpt, ... A Possible Function of Entamoeba histolytica in the Creation Model. by Frank Sherwin on October 14, 2009 PDF Download ...
A Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine Glycol
E. histolytica is exposed to oxidative stress during tissue invasion by phagocytes. Understanding DNA metabolism in E. ... histolytica, EhDNApolA. The biochemical characterization of recombinant EhDNApolA indicates that this protein is an active DNA ... histolytica is important because this parasite has shaped some metabolic pathways by horizontal gene transfer, infects ...
ENL-1 - Enolase 1 - Entamoeba histolytica - ENL-1 gene & protein
What Is Amebiasis (Entamoeba histolytica Infection)? Treatment & Symptoms
Amebiasis is an infection caused by a parasite known as Entamoeba histolytica. Signs and symptoms include stomach pain and ... Amebiasis (Entamoeba histolytica Infection) Topic Guide. *Doctors Notes on Amebiasis (Entamoeba histolytica Infection) ... Entamoeba histolytica and another ameba, Entamoeba dispar, which is about 10 times more common, look the same when seen under a ... Amebiasis is a disease caused by a one-celled parasite called Entamoeba histolytica. ...
Entamoeba histolytica - wikidoc
Entamoeba histolytica 4-11 y + ,10 cysts 2-4 we - + + + + Contaminated water and raw foods May cause intestinal amebiasis and ... Entamoeba histolytica Etiologic Agent of: Amoebiasis; Amoebic dysentery; Extraintestinal Amoebiasis, usually Amoebic Liver ... File:Entamoeba histolytica life cycle-en.svg This page is about microbiologic aspects of the organism(s). For clinical aspects ... Infection by Entamoeba histolytica occurs by ingestion of mature cysts in fecally contaminated food, water, or hands. ...
Cytopathogenicity of Entamoeba histolytica: hemolytic activity of trophozoite homogenates.
The species of Entamoeba included in the tests were ... The species of Entamoeba included in the tests were E. ... histolytica, E. invadens, E. moshkovskii, and the Laredo type of E. histolytica. The hemolytic activity was found to be dose- ... Entamoeba / pathogenicity*. Hemolysis*. Humans. Larva. Virulence. From MEDLINE®/PubMed®, a database of the U.S. National ... dependent and strain-specific, with E. histolytica being generally the species having the highest hemolytic potency.. ...
Symptoms of Entamoeba Histolytica
Entamoeba histolytica is a parasite that thrives in unsanitary environments. Symptoms of entamoeba only develop in a small ... An entamoeba histolytica infection most frequently occurs due to a lack of sanitation or hygiene. The University of Texas at ... Entamoeba histolytica is a single-celled parasite responsible for an infectious disease called amebiasis. So named because of ... Any questions about entamoeba histolytica or amebiasis should be directed to an individuals doctor. ...
cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. | PNAS
cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica.. B E Torian, B M Flores, ... A gamma gt11 cDNA library was constructed from poly(U)-Sepharose-selected Entamoeba histolytica trophozoite RNA in order to ... cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. ... cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. ...
RCSB PDB - 3M4P: Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
Entamoeba histolytica. Mutation(s): 0 Gene Names: 159.m00096, EHI_126920. EC: 6.1.1.22. ... Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate. *DOI: 10.2210/pdb3M4P/pdb ... X-ray crystal structure of asparaginyl-tRNA synthetase from the eukaryotic human pathogen Entamoeba histolytica.. Larson, E.T. ...
Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica. | Sigma-Aldrich
Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica. by Hugo Varet, Yana Shaulov, Odile Sismeiro ... Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica.. Scientific reports. (2018-06-15) ... During oxidative stress, we analyzed the interplay between an intestinal parasite (the pathogenic amoeba Entamoeba histolytica ... The factors identified here suggest that despite its old age in evolutionary terms, the protozoan E. histolytica displays key ...
Genome Sequencing of Clinically Important Strains of Entamoeba Histolytica | J. Craig Venter Institute
Genome Sequencing of Clinically Important Strains of Entamoeba Histolytica The protozoan parasite Entamoeba histolytica causes ... However, four out of five E. histolytica infections remain asymptomatic. What determines the outcome of an E. histolytica ... The DNA content of E. histolytica grown in axenic cultures (in the absence of bacteria) is at least 10 fold higher than in ... To date, there is only one available genome sequence of an E. histolytica strain (HM1:IMSS) and the genome is largely unclosed ...
The Biology of Entamoeba histolytica | The American Journal of Tropical Medicine and Hygiene
The second chapter, Cell Biology, is primarily concerned with the morphology of Entamoeba histolytica, and constitutes ... The Biology of Entamoeba histolytica by A. Martinez-Palomo. xii + 161 pages, illustrated. John Willey & Sons, Inc., 605 Third ... The second chapter, Cell Biology, is primarily concerned with the morphology of Entamoeba histolytica, and constitutes ...
Entamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo Library
E. histolytica is a parasite that causes amoebic dysentery in humans. Seen here is the active trophozoite form of the parasite ... Caption: Light microscope footage of Entamoeba histolytica protozoa. E. histolytica is a parasite that causes amoebic dysentery ... entamoeba histolytica, faecal-oral, fecal-oral route, gastrointestinal, grey, healthcare, hygiene, in vitro, intestinal, ... Light microscope footage of Entamoeba histolytica protozoa. ...
AmebiasisTrophozoitesInfectionAmoebiasisCystsPathogenicSpeciesGenusParasitic protozoanAmebic dysenteryGenomeProtozoan Entamoeba histolyticaParasitesAmoebaOrganismIsolatesPathogenicityDetectionMoshkovskiiInvasiveCystDysenteryLiver abscessCysteineGiardiaSerumMorphologicallyCryptosporidiumTrophozoiteQuestions about entamoeba histolyticaColiMorbidity and mortaDiagnosisEnteric protozoanStrainsAntibodiesMicroscopyAsymptomaticCausativeClinicalColitisGenePathogenStool samplesLarge intestineParasite entamoebaFecesLectinELISAIngestion
Amebiasis31
- Poor sanitary conditions are known to increase the risk of contracting amebiasis E. histolytica. (wikipedia.org)
- In the United States, there is a much higher rate of amebiasis-related mortality in California and Texas, which might be caused by the proximity of those states to E. histolytica-endemic areas, such as Mexico, other parts of Latin America, and Asia. (wikipedia.org)
- A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target," Journal of Biological Chemistry , vol. 285, no. 24, pp. 18516-18527, 2010. (hindawi.com)
- Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source of morbidity and mortality in the developing world. (nih.gov)
- What Is Amebiasis (Entamoeba histolytica Infection)? (emedicinehealth.com)
- Amebiasis is a disease caused by a parasite known as Entamoeba histolytica . (emedicinehealth.com)
- Amebiasis is a disease caused by a one-celled parasite called Entamoeba histolytica . (emedicinehealth.com)
- Entamoeba histolytica is a single-celled parasite responsible for an infectious disease called amebiasis. (bukisa.com)
- According to the National Institutes of Health, 90 percent of people who contract amebiasis experience no symptoms and many people who have entamoeba histolytica never develop the condition at all. (bukisa.com)
- The symptoms of an entamoeba histolytica infection are only manifested when amebiasis develops. (bukisa.com)
- The Centers for Disease Control report an amebiasis infection rate of less than one out of five people who contract entamoeba histolytica. (bukisa.com)
- When amebiasis develops in the liver, symptoms of entamoeba histolytica can include fever, nausea, and unintentional weight loss, among others. (bukisa.com)
- The NIH reports that the homosexual male population is most frequently affected in the U.S. While very few carriers actually develop amebiasis, it can develop even several months after coming into contact with entamoeba histolytica. (bukisa.com)
- Any questions about entamoeba histolytica or amebiasis should be directed to an individual's doctor. (bukisa.com)
- The observation that a histolytic cysteine proteinase gene is present only in pathogenic isolates of E. histolytica suggests that this aspect of virulence in amebiasis is genetically predetermined. (jci.org)
- Amebiasis is an enteric infection caused by Entamoeba histolytica , with symptoms ranging in severity from asymptomatic colonization to dysentery. (asm.org)
- Amebiasis, caused by the eukaryotic parasite Entamoeba histolytica , is an enormous global medical problem that still exists due to poor sanitary and unhygienic conditions. (frontiersin.org)
- Entamoeba histolytica is the causative agent of amebiasis and prevails in areas of poor sanitation. (pubmedcentralcanada.ca)
- The aim of this study was to characterize the specific interactions occurring between E. histolytica secreted cysteine proteinases and colonic mucin as a model to examine the initial events of invasive amebiasis. (asm.org)
- The enteric protozoan parasite Entamoeba histolytica is the causative agent of human amebiasis. (asm.org)
- Although less than 1% of E. histolytica infections result in invasive disease, amebiasis ranks second only to malaria as a cause of mortality due to a protozoan parasite. (asm.org)
- doi:10.1038/s41541-018-0060-x INTRODUCTION E. histolytica infection starts with the ingestion of amebic cysts from contaminated food or water, which after excystation form Amebiasis, a diarrheal disease caused by the enteric protozoan trophozoites in the intestinal lumen. (deepdyve.com)
- Amebiasis in the colon caused by the Protozoa Entamoeba histolytica, H&E stain. (gettyimages.it)
- Amebiasis and comparison of microscopy to ELISA technique in detection of Entamoeba histolytica and Entamoeba dispar. (semanticscholar.org)
- In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. (elsevier.com)
- Education and information about amebiasis, also known as Entamoeba histolytica infection, including frequently asked questions, biology and publications. (moguan.com.sg)
- Amebiasis happens when the parasite E. histolytica gets into your digestive system. (staywellsolutionsonline.com)
- Once you develop antibodies to E. histolytica, they may stay in your blood even after you no longer have amebiasis. (staywellsolutionsonline.com)
- Amebiasis is caused by Entamoeba Histolytica , a protozoan that's found worldwide. (soundhealthsolution.com)
- Amebiasis may be a parasitic infection caused by the protozoan organism Entamoeba Histolytica, which may make each to intestinal illness (e.g., colitis) and to numerous extraintestinal manifestations, together with the liver symptom (most common) and pleuropulmonary, cardiac, and cerebral dissemination. (soundhealthsolution.com)
- Direct detection of Entamoeba histolytica in stool specimens is recommended to diagnose intestinal amebiasis. (testcatalog.org)
Trophozoites21
- While E. histolytica trophozoites are more likely than E. dispar and E. moshkovskii to contain ingested erythrocytes, most often E. histolytica trophozoites in patient stools lack ingested red cells ( 7 , 10 , 11 ). (asm.org)
- We collected 32 plants used in Northeast Mexican traditional medicine and the methanolic extracts of these species were screened for antiprotozoal activity against E. histolytica trophozoites using in vitro tests. (mdpi.com)
- In 90% of the infected patients, E. histolytica trophozoites normally inhabit the colon and spend their time in the host as a non-pathogenic commensal. (frontiersin.org)
- The bulk of previous studies on the prevalence of E. histolytica were based on stool microscopy, which is of low sensitivity and specificity and cannot distinguish E. histolytica cysts or trophozoites from E. dispar or E. moshkovskii . (antimicrobe.org)
- Specificity: These antibodies recognize Entamoeba histolytica trophozoites and cysts. (qedbio.com)
- These antibodies have been qualified for use in ELISA to detect E. histolytica trophozoites and cysts. (qedbio.com)
- The ability of Entamoeba histolytica trophozoites to destroy monolayers of baby hamster kidney cells is inhibited by allicin, one of the active principles of garlic. (asm.org)
- It is due to the hematogenous spread of the E. histolytica trophozoites from intestine to liver through the portal vein. (asm.org)
- Animals were inoculated with E. histolytica and sacrificed 48 hours later to collect caecum samples that were used for quantitative analyses of lesions, trophozoites, NK1.1+ T lymphocytes and expression of the mucus protein MUC-2 by immunohistochemistry technique. (pagepress.org)
- The extension of necrotic mucosa was larger and the number of trophozoites higher in Entamoeba (Eh)-infected CD1-/- mice when compared with Eh-infected WT mice. (pagepress.org)
- Moreover, the risk of death for infected young children specific adherence of E. histolytica trophozoites to colonic mucins is among the highest of all diarrheal diseases as determined in the in vitro. (deepdyve.com)
- Standardized conditions for the soaking of E. histolytica trophozoites with siRNAs result in highly specific and significant silencing of parasite cognate genes. (pasteur.fr)
- E. histolytica trophozoites show a dramatic virulence variability that has been related to a great genome plasticity, with ploidy changes, unscheduled gene amplification, and duplication events, which might be associated with genetic rearrangements mediated by homologous recombination (HR) events [ 1 , 17 , 32 ]. (parasite-journal.org)
- Immunohistochemical staining of trophozoites (brown) using specific anti-Entamoeba histolytica macrophage migration inhibitory factor antibodies in a patient with amebic colitis. (moguan.com.sg)
- Serology or examination with trophozoites or cysts in it are the two main tests for diagnosis of Entamoeba histolytica infection. (osmosis.org)
- The minimum detection sensitivity level of antigen entamoeba histolytica using current human Entamoeba histolytica Ag ELISA kit was 5x 10 3 - 6x 10 3 trophozoites per mL of stool suspension. (elisakits.co.uk)
- Ingestion of Entamoeba Histolytica cysts from the surroundings is followed by excitation within the terminal small intestine or colon to create extremely motile trophozoites. (soundhealthsolution.com)
- E. histolytica trophozoites overexpressing wildtype EhGα1 in an inducible manner exhibit an enhanced ability to kill host cells that may be wholly or partially due to enhanced host cell attachment. (scienceexchange.com)
- Ultimately, the cysts of Entamoeba histolytica enter the small intestine and release trophozoites, which subsequently invade the epithelial cells of the large intestines, which can then spread from the intestines to other organs. (scalarlight.com)
- Accumulation of E. histolytica trophozoites in mitosis was observed after culture in 100 μM oryzalin. (allenpress.com)
- The inhibitory effect of oryzalin on the growth of E. histolytica trophozoites was abrogated by removal of the drug after exposure to 100 μM for 2 days. (allenpress.com)
Infection41
- E. histolytica infection is estimated to kill more than 55,000 people each year. (wikipedia.org)
- The infection can occur when a person puts anything into their mouth that has touched the feces of a person who is infected with E. histolytica, swallows something, such as water or food, that is contaminated with E. histolytica, or swallows E. histolytica cysts (eggs) picked up from contaminated surfaces or fingers. (wikipedia.org)
- R. C. MacFarlane and U. Singh, "Identification of differentially expressed genes in virulent and nonvirulent Entamoeba species: potential implications for amebic pathogenesis," Infection and Immunity , vol. 74, no. 1, pp. 340-351, 2006. (hindawi.com)
- Amoebiasis, or amoebic dysentery, is a term used to describe an infection caused by the protozoan Entamoeba histolytica [ 1 ]. (hindawi.com)
- E. histolytica infection can be treated successfully with antibiotics . (emedicinehealth.com)
- Only about 10% to 20% of people who are infected with E. histolytica become sick from the infection. (emedicinehealth.com)
- Unlike infection with E. histolytica , which sometimes makes people sick, infection with E. dispar does not make people sick and therefore does not need to be treated. (emedicinehealth.com)
- You will be treated with only one antibiotic if your E. histolytica infection has not made you sick. (emedicinehealth.com)
- Infection by Entamoeba histolytica occurs by ingestion of mature cysts in fecally contaminated food, water, or hands. (wikidoc.org)
- An entamoeba histolytica infection most frequently occurs due to a lack of sanitation or hygiene. (bukisa.com)
- Early symptoms of an entamoeba histolytica infection are generally digestive in nature. (bukisa.com)
- In the most severe cases of an entamoeba histolytica infection, amebic dysentery includes symptoms like blood in stool, nausea, vomiting, and a fever. (bukisa.com)
- What determines the outcome of an E. histolytica infection is largely unknown. (jcvi.org)
- Culture along with isoenzyme (zymodeme) analysis enables differentiation of E. histolytica from E. dispar or E. moshkovskii and was considered the gold standard for diagnosing amebic infection in the last 2 decades. (asm.org)
- The sensitivities and specificities of traditional PCR-based methods for the diagnosis of E. histolytica infection in stool samples were comparable to those of culture and antigen detection ( 8 , 12 , 15 ). (asm.org)
- Using a mouse model expressing the mutation, we tested the impact of the Q223R mutation on the innate immune response to E. histolytica infection. (asm.org)
- Leptin expression was increased in the cecum by E. histolytica infection, suggesting that leptin could serve as a homing signal for neutrophils to the gut. (asm.org)
- The mouse model of an E. histolytica cecal infection was used to determine the differences between Q223 and R223 mice early during an infection. (asm.org)
- Given the high sensitivity and specificity of the developed PCR assay, the inability of microscopy to distinguish between the two ameba species, and the time it takes to culture and subsequently differentiate entamoebae by isoenzyme analysis, this assay is more suitable than microscopy or culture to correctly diagnose intestinal E. histolytica or E. dispar infection. (asm.org)
- Prior to invasive disease, E. histolytica may reside in the human gut for months or even years as asymptomatic infection ( 15 , 37 ). (asm.org)
- The test will not be performed if the patient is being treated for an Entamoeba infection or as a follow up specimen following treatment. (publichealthontario.ca)
- Serologic studies are more reliable, since only E. histolytica infection generates a serum antibody response ( 54 ) and these suggest that up to 8.4% of persons in endemic countries have been exposed ( 8 ). (antimicrobe.org)
- I n developed countries, populations at risk for E. histolytica infection include returned travelers or expatriates and immigrants from endemic countries and most cases of invasive disease are imported. (antimicrobe.org)
- Asymptomatic infection with E. histolytica but not E. dispar is associated with a positive serum anti-amebic antibody and, frequently, a positive stool antigen test. (antimicrobe.org)
- Invasive amoebiasis, caused by infection with the human parasite Entamoeba histolytica remains a major cause of morbidity and mortality in some less-developed countries. (biomedcentral.com)
- The diseases is caused by infection with the protozoan Entamoeba histolytica , although it is now clear that only a minority of those infected will develop clinical amoebiasis [ 1 ]. (biomedcentral.com)
- Herein, we explored the role of NKT cells in E. histolytica infection using C57BL/6 wild-type and CD1-/- mice. (pagepress.org)
- Our results showed that NKT lymphocytes contribute to resistance against Entamoeba histolytica infection and to the control of inflammation in the colitis induced by infection. (pagepress.org)
- Entamoeba histolytica and Entamoeba dispar: prevalence infection in a rural Mexican community. (semanticscholar.org)
- Amoebiasis, also known amoebic dysentery, is an infection caused by any of the amoebae of the Entamoeba group. (moguan.com.sg)
- The diagnosis of E. histolytica infection has traditionally relied upon microscopic examination of fresh or fixed stool specimens. (moguan.com.sg)
- Symptoms are most common during infection by Entamoeba histolytica. (moguan.com.sg)
- Infection of the large intestine by Entamoeba histolytica may result in an illness of variable severity ranging from mild, chronic diarrhea to fulminant dysentery. (cdc.gov)
- Infection with the human pathogenic parasite Entamoeba histolytica has not been well-characterized in northeastern Brazil. (elsevier.com)
- In this study, the prevalence of E. histolytica infection in a slum in northeastern Brazil was assayed using an enzyme-linked immunosorbent assay (ELISA) for antibodies against the galactose/N-acetyl-D-galactosamine (Gal/GalNAc)-inhibitable adherence lectin of E. histolytica. (elsevier.com)
- Although the overall colonization rate by microscopy was only 9%, with a third identified as E. histolytica, up to 40% of older children develop serologic evidence of having experienced pathogenic E. histolytica infection. (elsevier.com)
- The results of this study demonstrate that this community in northeastern Brazil is highly endemic for E. histolytica with infection rates similar to other developing nations. (elsevier.com)
- E histolytica is able to cause a spectrum of illnesses, intestinal conditions resulting from this infection include asymptomatic infection, acute proctocolitis (dysentery), ameboma, perianal ulceration, symptomatic non-invasive infection, chronic non-dysenteric colitis, fulminant colitis with perforation and toxic megacolon. (elisakits.co.uk)
- Damage to the colon is caused by neutrophils that respond to infection from E. histolytica . (waterpathogens.org)
- Humans are the only reservoir for contamination of Entamoeba histolytica as the infection occurs by ingestion of mature cysts in food or water or on hands contaminated by feces. (scalarlight.com)
- Infection with E. histolytica occurs orally with the intake of cysts. (r-biopharm.com)
Amoebiasis22
- Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. (wikipedia.org)
- Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. (hindawi.com)
- The search was conducted between February 3, 2018 and April 6, 2018, looking for publications that contain "amoebiasis," "Entamoeba histolytica," "amoebic colitis," and "extraintestinal amoebiasis" in the title or abstract. (hindawi.com)
- Entamoeba histolytica is the causative agent of amoebiasis that occasionally results in death. (answersingenesis.org)
- Entamoeba histolytica is a an anaerobic parasitic protozoan that is responsible for the development of amoebiasis. (wikidoc.org)
- During oxidative stress, we analyzed the interplay between an intestinal parasite (the pathogenic amoeba Entamoeba histolytica - the agent of amoebiasis) and enteric bacteria (microbiome residents, pathogens and probiotics). (sigmaaldrich.com)
- Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries. (mdpi.com)
- Amoebiasis caused by the protozoan parasite Entamoeba histolytica remains a public health problem in developing countries, making the identification of new anti-amoebic compounds a continuing priority. (portlandpress.com)
- Entamoeba histolytica is an anaerobic parasitic protozoan that predominantly infects humans and other primates causing amoebiasis. (qedbio.com)
- IMPORTANCE Entamoeba histolytica causes amoebiasis, a potentially fatal diarrheal disease. (asm.org)
- Amoebiasis is caused by the enteric protozoan Entamoeba histolytica , which affects 50 million people worldwide and leads to 100,000 fatal cases annually ( 19 , 21 ). (asm.org)
- Entamoeba histolytica is a protozoan that causes amoebiasis. (pagepress.org)
- Entamoeba histolytica is a cosmopolitan, parasitic protozoan of human large intestine, which is a causative agent of amoebiasis. (peertechz.com)
- Entamoeba histolytica , the protozoan responsible for human amoebiasis, exhibits a great genome plasticity that is probably related to homologous recombination events. (parasite-journal.org)
- Entamoeba histolytica is the protozoan causative of human amoebiasis, a neglected parasitic disease that affects about 50 million people worldwide [ 29 ]. (parasite-journal.org)
- Entamoeba histolytica is an anaerobic parasitic protozoan that causes amoebiasis, presenting with either bloody diarrhea or liver abscesses with an "anchovy paste" exudate. (osmosis.org)
- Entamoeba histolytica is an anaerobic parasitic amoebozoa which is the causative agent of amoebiasis. (elisakits.co.uk)
- Prevalence of amoebiasis in a model research community and its confirmation using stool antigen elisa for Entamoeba histolytica. (elisakits.co.uk)
- Entamoeba histolytica is an invasive, pathogenic protozoan, causing amoebiasis, and an important cause of diarrhea in developing countries. (waterpathogens.org)
- Scalar energy is capable of disassembling Entamoeba histolytica, the causative agent of amoebiasis. (scalarlight.com)
- Among them Entamoeba histolytica is an important human pathogen causing amoebic dysentery as well as hepatic amoebiasis. (laboratorytests.org)
- Definitive diagnosis of amoebiasis depends on the demonstration of E. histolytica trophozoite or cyst in stool. (laboratorytests.org)
Cysts6
- causative agent of amebic dysentery, Entamoeba histolytica , is found in the intestine of infected individuals, in whom it forms cysts that pass to the outside in feces. (britannica.com)
- Swallows E. histolytica cysts (eggs) picked up from contaminated surfaces or fingers. (emedicinehealth.com)
- The cysts of E. histolytica contain 4 nuclei with even distribution of chromatin between the nuclei. (wikidoc.org)
- Light microscopy of stool, the traditional diagnostic method, is unable to differentiate between cysts of E histolytica and the non-pathogenic amoeba E dispar . (bmj.com)
- As is the case for other intestinal protozoan pathogens, wastewater treatment techniques are reported not to be very efficient for E. histolytica elimination possibly because of their resistance to disinfectants and the small size of the cysts. (waterpathogens.org)
- I think I learned that the number of nuclei for E. histolytica cysts was four or less and for E. coli it was more than four. (laboratorytests.org)
Pathogenic12
- The pathogenic nature of E. histolytica was first reported by Fedor A. Lösch in 1875, but it was not given its Latin name until Fritz Schaudinn described it in 1903. (wikipedia.org)
- By using an antiserum to the purified lectin, the corresponding cDNA was isolated from an expression library of the pathogenic E. histolytica isolate HM-1:IMSS. (pnas.org)
- While the controlling factors that direct invasiveness of E. histolytica are not well understood, the progression from originally free-living single-celled eukaryotes (neutral or beneficial) toward a pathogenic condition after the Fall could have occurred through a number of mechanisms leading to a parasitic condition. (answersingenesis.org)
- cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. (pnas.org)
- E. histolytica , which is pathogenic, and E. dispar , which is not ( 71 ). (antimicrobe.org)
- Although many infectious diseases receive little attention in today's world, the pathogenic intestinal parasite E. histolytica occupies a major place in the list of ignored illnesses. (pubmedcentralcanada.ca)
- E. dispar is a commensal in the human digestive tract, and E. histolytica is the only one thought to be pathogenic in humans. (loinc.org)
- Pathogenic species Entamoeba histolytica has to be differentiated from other nonpathogenic amoebas of the intestine, so called commensals, that very often live in the human large intestine and remain harmless. (peertechz.com)
- Other intestinal commensals are Entamoeba dispar and Entamoeba moshkovskii, morphologically the same as pathogenic species Entamoeba histolytica sensu stricto. (peertechz.com)
- Heterotrimeric G-protein signaling is critical to pathogenic processes in Entamoeba histolytica. (scienceexchange.com)
- Our understanding of its epidemiology has dramatically changed since this amoeba was distinguished from another morphologically similar one, Entamoeba dispar , a non pathogenic and commensal parasite. (waterpathogens.org)
- It is estimated that approximately 10 % of the half billion people infected each year are infected with the pathogenic E. histolytica. (mayocliniclabs.com)
Species17
- It has been established that the invasive and noninvasive forms represent two separate species, respectively E. histolytica and E. dispar . (wikidoc.org)
- These two species are morphologically indistinguishable unless E. histolytica is observed with ingested red blood cells (erythrophagocystosis). (wikidoc.org)
- The species of Entamoeba included in the tests were E. histolytica, E. invadens, E. moshkovskii, and the Laredo type of E. histolytica. (biomedsearch.com)
- The hemolytic activity was found to be dose-dependent and strain-specific, with E. histolytica being generally the species having the highest hemolytic potency. (biomedsearch.com)
- Not only is microscopy unable to differentiate E. histolytica from E. dispar or E. moshkovskii , it is at best only 10 to 60% sensitive and confounded with false-positive results due to misidentification of macrophages and nonpathogenic species of Entamoeba ( 12 , 13 , 18 , 23 ). (asm.org)
- The two pairs of primers used were specific for the respective ameba species, and results were not influenced by the presence of other Entamoeba species even when present in exceeding amounts. (asm.org)
- Compared to culture and subsequent ameba differentiation by isoenzyme analysis, PCR was 100% specific for each of the two Entamoeba species. (asm.org)
- However, the recent identification of Entamoeba dispar as a separate but nonpathogenic species which is morphologically indistinguishable from E. histolytica and does not require treatment has indicated the need of alternative detection methods which are able to differentiate between the two organisms ( 8 ). (asm.org)
- During its life cycle, the unicellular parasite Entamoeba histolytica is challenged by a wide variety of environmental stresses, such as fluctuation in glucose concentration, changes in gut microbiota composition, and the release of oxidative and nitrosative species from neutrophils and macrophages. (frontiersin.org)
- Additional species that have been found in the gut include Entamoeba moshkovskii, Entamoeba poleki, Entamoeba coli, and Entamoeba hartmanni. (loinc.org)
- Entamoeba histolytica and Entamoeba dispar are a complex of two different but morphologically identical species. (loinc.org)
- E. histolytica is an invasive species assoicated with cell and tissue damage. (loinc.org)
- Interestingly, it is now known that many suspected cases of E. histolytica that are based on microscopic examination are actually those of Entamoeba dispar , a benign species, which is actually up to 10 times more common that it's virulent cousin. (blogspot.com)
- The genus Entamoeba is composed of five species that infect humans: E. histolytica, E. dispar, E. hartmanni, E. coli, E. polecki and E. gingivalis. (moguan.com.sg)
- Entamoeba invadens is a species that can cause a disease similar to E. histolytica but in reptiles. (moguan.com.sg)
- About 80-90% of infections are asymptomatic and are likely due to the nonpathogenic species E. dispar or E. moshkovskii , therefore the worldwide incidence of E. histolytica is, more likely, estimated to be 5 million cases annually, with global mortality still at 100.000 persons per annum. (waterpathogens.org)
- Entamoeba species are single cell organisms with two life cycle stages. (waterpathogens.org)
Genus4
- Entamoeba histolytica is an anaerobic parasitic protozoan, part of the genus Entamoeba, which predominantly infects humans and other primates. (uniprot.org)
- Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. (wikipedia.org)
- Genus Entamoeba includes a group of amoebic parasites. (laboratorytests.org)
- Entamoeba histolytica adalah protozoa parasit , bagian dari genus Entamoeba . (wikipedia.org)
Parasitic protozoan2
- The enzyme from the parasitic protozoan Entamoeba histolytica was crystallized in the presence of small ligands to generate snapshots of the lysine-adenylate formation. (rcsb.org)
- Entamoeba histolytica is an anaerobic parasitic protozoan that causes amoebic dysentery. (pubmedcentralcanada.ca)
Amebic dysentery4
- E. histolytica is the cause of human amebic dysentery. (britannica.com)
- Cysteine proteinases are hypothesized to be important virulence factors of Entamoeba histolytica, the causative agent of amebic dysentery and liver abscesses. (jci.org)
- E histolytica causes amebic dysentery and can cause liver abscesses, E coli is normal part of colon . (healthtap.com)
- The unicellular eukaryote Entamoeba histolytica is a human parasite that causes amebic dysentery and liver abscess. (pubmedcentralcanada.ca)
Genome17
- Entamoeba histolytica (strain HM-1:IMSS) is the first human amoeba to have its genome sequenced, assembled and analyzed. (uniprot.org)
- The reference proteome of Entamoeba histolytica is derived from the genome sequence published in 2005. (uniprot.org)
- The E. histolytica genome was sequenced, assembled, and automatically annotated in 2005. (wikipedia.org)
- The genome of E. histolytica has been found to have snoRNAs with opisthokont-like features. (wikipedia.org)
- A survey of whole genome shotgun sequences of the protozoan parasite Entamoeba histolytica revealed three families of non-long terminal repeat (LTR) retrotransposons or long interspersed elements (LINEs) (called EhLINEs in this report). (nih.gov)
- To date, there is only one available genome sequence of an E. histolytica strain (HM1:IMSS) and the genome is largely unclosed and fragmented. (jcvi.org)
- The genome of the protist parasite Entamoeba histolytica. (genscript.com)
- Recently, we identified several members of a class of intramembrane rhomboid proteases in the E. histolytica genome ( 4 ). (asm.org)
- The E. histolytica genome encodes four rhomboid-like genes, with only a single gene containing the necessary catalytic residues for proteolytic activity ( 4 ). (asm.org)
- Genetically E. histolytica exhibits a number of unusual features including having approximately 20% of its genome comprised of repetitive elements. (biomedcentral.com)
- Of the many families of repetitive elements present in the genome of E. histolytica we have examined in detail just one - EhSINE1. (biomedcentral.com)
- For this reason, after five years from the initial submission of the Entamoeba histolytica draft genome publication, we have re-examined the original 23 Mb assembly and the annotation of the predicted genes. (pubmedcentralcanada.ca)
- This new genome annotation and analysis represents a more refined and accurate blueprint of the pathogen genome, and provides an upgraded tool as reference for the study of many important aspects of E. histolytica biology, such as genome evolution and pathogenesis. (pubmedcentralcanada.ca)
- The draft genome of E. histolytica , published in 2005, provided the scientific community with the first comprehensive view of the gene set for this parasite and important tools for elucidating the genetic basis of Entamoeba pathogenicity. (pubmedcentralcanada.ca)
- Because complete genetic knowledge is critical for drug discovery and potential vaccine development for amoebiases, we have re-examined the original draft genome for E. histolytica . (pubmedcentralcanada.ca)
- Recent studies have suggested that a considerable number of genes coding for proteolytic enzymes are present within the E. histolytica genome and questions remain about the mode of expression of the various molecules. (biomedcentral.com)
- By homology search within the recently published amoeba genome, we identified a total of 86 E. histolytica genes coding for putative peptidases, including 46 recently described peptidase genes. (biomedcentral.com)
Protozoan Entamoeba histolytica2
- is caused by the protozoan Entamoeba histolytica . (britannica.com)
- Approximately 50 million people in the world are infected with the protozoan Entamoeba histolytica. (scalarlight.com)
Parasites8
- There is a need for parasites such as Entamoeba histolytica to be addressed from a biblical perspective that may include their original symbiotic or mutualistic association in man. (answersingenesis.org)
- One problem is that other parasites and cells can look very similar to E. histolytica when seen under a microscope. (emedicinehealth.com)
- Classic microscopic examination of the parasite E. histolytica in stool cannot differentiate it from the nonpathogenic but identically appearing parasites Entamoeba dispar and Entamoeba moshkovskii . (asm.org)
- A closed-tube, real-time PCR assay was developed for sensitive and specific detection and differentiation of the two closely related intestinal protozoan parasites Entamoeba histolytica and Entamoeba dispar directly from human feces. (asm.org)
- Entamoeba histolytica is one of the most common parasites of humans and apes, with some estimates going as high as 50 million people infected worldwide. (blogspot.com)
- Entamoeba are pseudopod-forming, protozoan parasites in the subphylum Sarcodina. (moguan.com.sg)
- Diagnosis can be difficult because other parasites can look very similar to E. histolytica when seen under a microscope. (moguan.com.sg)
- Entamoeba histolytica are intestinal parasites that infect a half billion people worldwide annually. (mayocliniclabs.com)
Amoeba2
- Amebic dysentry is caused by a parasite amoeba called antamoeba histolytica.And bacilary dysentry is caused by several bacteria like e coli.Schigella, or salmonella both cause diarrhea with or without mucus/blood. (healthtap.com)
- Further studies are required to define the precise role of most of the proteolytic enzyme for amoeba cell biology but in particular for E. histolytica virulence. (biomedcentral.com)
Organism5
- The name of the organism is entamoeba histolytica. (healthtap.com)
- New drugs need to be researched for the treatment of E. histolytica because of high failure rate of the two drugs against this killer organism. (academicjournals.org)
- Finally, Western blot analysis demonstrated that EhRab11 and a previously described Rab7-like GTPase from E. histolytica was enriched in magnetically purified endosomal compartments of this organism. (unl.edu)
- The E. HISTOLYTICA II™ test is a second generation monoclonal antibody-based ELISA for the rapid detection of Entamoeba histolytica adhesin in fecal specimens.It also indicates the presence of the organism in feces as a diagnostic aid. (moguan.com.sg)
- Collectively, our studies suggest that E. histolytica possesses a divergent heterotrimeric G-protein signaling axis that modulates key aspects of cellular processes related to the pathogenesis of this infectious organism. (scienceexchange.com)
Isolates6
- Expression of the 56-kilodalton (kDa) neutral thiol proteinase has been shown to correlate with the potential of clinical isolates of Entamoeba histolytica to produce invasive disease. (nih.gov)
- The release of a histolytic cysteine proteinase from E. histolytica correlates with the pathogenicity of both axenic strains and recent clinical isolates as determined by clinical history of invasive disease, zymodeme analysis, and cytopathic effect. (jci.org)
- Due to their mobile nature, some EhSINE copies may occupy different genomic locations among isolates of E. histolytica possibly affecting adjacent gene expression. (omicsonline.org)
- Using an oligonucleotide microarray, peptidase gene expression patterns of 7 different E. histolytica isolates as well as of heat stressed cells were analysed. (biomedcentral.com)
- Under standard culture conditions or upon heat-stress only a relatively small number of these genes is significantly expressed and only very few variations become apparent between various clinical E. histolytica isolates, calling into question the importance of these enzymes in E. histolytica pathogenicity. (biomedcentral.com)
- We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model. (elsevier.com)
Pathogenicity2
- A number of studies have shown that peptidases and in particular cysteine peptidases constitute major pathogenicity factors in Entamoeba histolytica . (biomedcentral.com)
- Cysteine peptidases are considered to play a major role for the pathogenicity of E. histolytica as suggested by a large number of in vitro and in vivo studies [ 1 - 9 ]. (biomedcentral.com)
Detection18
- A single-tube multiprobe real-time PCR assay for simultaneous detection of Entamoeba histolytica and Entamoeba dispar was developed. (uptodate.com)
- We developed a real-time-PCR assay utilizing a molecular-beacon probe for the detection of Entamoeba histolytica and compared its sensitivity to stool antigen detection and traditional PCR. (asm.org)
- A total of 205 stool and liver abscess pus specimens from patients and controls were used for this purpose, 101 (49%) of which were positive by the TechLab E. histolytica -specific antigen detection test, while the other 104 (51%) stool and liver abscess pus specimens were negative by the antigen detection test. (asm.org)
- In conclusion, all three methods for the detection of E. histolytica were highly specific, with real-time PCR being the most sensitive. (asm.org)
- New approaches to the detection of E. histolytica are based on the detection of an E. histolytica -specific antigen and DNA. (asm.org)
- The TechLab (Blacksburg, Virginia) Entamoeba histolytica II kit is the only Food and Drug Administration-approved test that is specific and sensitive for the detection of E. histolytica in feces ( 15 ). (asm.org)
- Traditionally, the laboratory detection of E. histolytica in human feces has relied upon the microscopic examination of fresh or fixed stool samples. (asm.org)
- Antigen detection was performed on all stool samples and on two of the pus samples, using the Techlab E histolytica II kit (Techlab, Blacksburg, Virginia, USA), an enzyme linked immunosorbent assay (ELISA) method based upon detection of the galactose adhesin of E histolytica . (bmj.com)
- Therefore, understanding how E. histolytica evades immune detection is of great interest. (asm.org)
- PCR, real-time PCR, and TechLab E. histolytica II antigen detection enzyme-linked immunosorbent assay [ELISA]) had high sensitivity ( 4 , 11 , 18 ). (asm.org)
- The available antigen detection tests such as TechLab E. histolytica II ELISA, which detects E. histolytica lectin antigen, can be used for diagnosis of acute ALA patients who have not received treatment ( 23 ). (asm.org)
- This code describes molecular detection of Entamoeba histolytica/dispar complex (E. histolytica, E. dispar, E. nuttalli, and E ecuadoriensis) DNA by RT-PCR. (loinc.org)
- A simple stool concentration method for the detection and preservation of the vegetative forms of Entamoeba histolytica/Entamoeba dispar. (semanticscholar.org)
- Detection and differentiation of Entamoeba histolytica and Entamoeba dispar by polymerase chain reaction in a community in Zulia State, Venezuela]. (semanticscholar.org)
- 5%) of D. fragilis and E. dispar and no detection of E. histolytica and C. spp in all participants with GI symptoms. (diva-portal.org)
- The Entamoeba histolytica IgG-ELISA is done for the detection of antibodies against Entamoeba histolytica antigens in human serum or plasma. (apollodiagnostics.in)
- Since this method cannot always differentiate an abscess caused by E. histolytica from other abscesses or carcinoma, an antibody detection should be made to support other clinical findings. (r-biopharm.com)
- Direct detection of Entameba in the punctate is not of importance, because ameba are rarely detectable in abscess material. (r-biopharm.com)
Moshkovskii4
- The test did not show cross reactivity with DNA from Entamoeba moshkovskii, Giardia lamblia , Cryptosporidium sp. (uptodate.com)
- Eight amoebas ( Endolimax nana , Entamoeba coli , E. histolytica , E. dispar , E. hartmanni , Iodamoeba bütschlii , E. moshkovskii and E. polecki ) reside in the human intestinal lumen. (answersingenesis.org)
- E histolytica / E dispar / E moshkovskii ). (antimicrobe.org)
- E. histolytica, E. dispar, and E.moshkovskii are morphologically identical but are different biochemically and genetically. (loinc.org)
Invasive7
- The protozoan parasite Entamoeba histolytica causes invasive intestinal and extraintestinal infections in about 50 million people world-wide resulting in a death toll of up to 100,000 people annually. (jcvi.org)
- To interrupt transmission of the parasite and to avoid progression of infected individuals to invasive disease, treatment of E. histolytica carriers has been recommended ( 36 ). (asm.org)
- W hile an estimated 90% of E. histolytica infections are asymptomatic, prospective studies of asymptomatic carriers indicate a risk of invasive disease of 5/56 (9%) over the course of 6-12 months ( 26 ). (antimicrobe.org)
- Accordingly, the risk of developing invasive disease, as well as decreased transmission, are rationales for treating asymptomatic carriers of E. histolytica , however WHO recommends against treatment of asymptomatic patients when only a morphologic diagnosis by stool examination is available (i.e. (antimicrobe.org)
- Value of microscopy in the diagnosis of dysentery associated with invasive Entamoeba histolytica. (bmj.com)
- The adherent mucous gel layer lining the colonic epithelium is the first line of host defense against invasive pathogens, such as Entamoeba histolytica . (asm.org)
- E.histolytica always elicits a serological response whether it is invasive or whether the person is asymptomatic -- only 10 precent do develop serious disease. (parasite.org.au)
Cyst3
- E. histolytica quadrinucleate cyst with chromatoid bodies. (moguan.com.sg)
- Entamoeba histolytica cyst - spherical 10 - 20 microns (average 12 - 15). (parasite.org.au)
- In case of E. histolytica, as the cyst matures, the nucleus undergoes two successive mitotic divisions to form two and then four nuclei. (laboratorytests.org)
Dysentery4
- E. histolytica is a parasite that causes amoebic dysentery in humans. (sciencephoto.com)
- The intestinal protozoan parasite Entamoeba histolytica is endemic in large parts of the world and is considered responsible for millions of cases of dysentery and liver abscess each year ( 32 ). (asm.org)
- Clinical syndromes associated with intestinal E. histolytica disease include diarrhea, acute rectocolitis (dysentery), fulminant colitis (acute necrotizing colitis) with perforation, toxic megacolon, chronic nondysenteric colitis, ameboma, and perianal ulceration. (antimicrobe.org)
- The protozoan parasite Entamoeba histolytica is the causative agent of amoebic dysentery and amoebic liver abscess. (bmj.com)
Liver abscess3
- DNA was extracted from the stool and liver abscess pus specimens by the QIAGEN method and the small-subunit rRNA gene of E. histolytica and then amplified by traditional and real-time PCR. (asm.org)
- Several PCR-based tests that detect E. histolytica -specific DNA in stool samples and liver abscess pus have also been developed and evaluated ( 6 , 12 , 13 , 24 , 25 , 28 ). (asm.org)
- Only Entamoeba histolytica is capable of tissue invasion and causing an amoebic liver abscess. (publichealthontario.ca)
Cysteine5
- It inhibits many of the key enzymes that are involved in the metabolism and virulence of the parasite Entamoeba histolytica through S-nitrosylation of essential cysteine residues. (asm.org)
- An important virulence factor, a 27-kDa cysteine protease, was also enriched in early and late endosomes of E. histolytica . (unl.edu)
- Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. (asm.org)
- E. histolytica secreted products were examined for mucinase activity utilizing mucin metabolically labeled with [ 35 S]cysteine as a substrate. (asm.org)
- These results are the first to show that E. histolytica cysteine proteinases alter the protective function of the mucous barrier by disrupting the structure of the MUC2 polymer. (asm.org)
Giardia1
- We surveyed the prevalence of Dientamoeba fragilis , Giardia duodenalis, Entamoeba histolytica, Entamoeba dispar , and Cryptosporidium spp in individuals with and without gastrointestinal (GI) symptoms residing in and around Da Nang city, Vietnam. (diva-portal.org)
Serum5
- The library was screened with rabbit polyclonal anti-E. histolytica serum. (pnas.org)
- We demonstrate that E. histolytica acquires and displays human cell membrane proteins through trogocytosis and that this leads to protection from lysis by human serum. (asm.org)
- Here, we demonstrate for the first time that E. histolytica acquires and displays human cell membrane proteins by taking "bites" of human cell material in a process named trogocytosis ("trogo-" means "nibble"), and that this allows amoebae to survive in human serum. (asm.org)
- Western blots using excretory-secretory antigen (ESA) collected from axenically grown Entamoeba histolytica were probed with the above serum samples. (asm.org)
- The RIDASCREEN® Entamoeba histolytica IgG test is an enzyme immunoassay for the qualitative determination of IgG antibodies against Entamoeba histolytica in human serum. (r-biopharm.com)
Morphologically1
- It has been established that Entamoeba histolytica is morphologically identical to the non-pathogen Entamoeba dispar . (publichealthontario.ca)
Cryptosporidium1
- The major etiological agents of parasitic diarrhea are considered to be Entamoeba histolytica, Cryptosporidium spp. (omicsonline.org)
Trophozoite4
- Cytopathogenicity of Entamoeba histolytica: hemolytic activity of trophozoite homogenates. (biomedsearch.com)
- A gamma gt11 cDNA library was constructed from poly(U)-Sepharose-selected Entamoeba histolytica trophozoite RNA in order to clone and identify surface antigens. (pnas.org)
- MTT assays in trophozoite cultures of E. histolytica exposed to each peptide (1-1000 μM) showed that Lfampin is far more amoebicidal than Lfcins. (portlandpress.com)
- Entamoeba histolytica: adhesins and lectins in the trophozoite surface. (elisakits.co.uk)
Questions about entamoeba histolytica1
- Please feel free to email us at the email address below with any insights, coments, or questions about entamoeba histolytica. (entamoebahistolytica.org)
Coli4
- Are entamoeba histolytica and entamoeba coli the same pathogen? (healthtap.com)
- What is the difference between entamoeba histolytica and entamoeba coli? (healthtap.com)
- Entamoeba coli is a commensal of large intestine, but doesn't invade tissues. (laboratorytests.org)
- Following are the structural differences between E. histolytica and E. coli. (laboratorytests.org)
Morbidity and morta2
- IMPORTANCE The Q223R leptin receptor mutation results in increased susceptibility of children and adults to E. histolytica , one of the leading causes of diarrhea morbidity and mortality in children of the developing world. (asm.org)
- The enteric protozoan parasite Entamoeba histolytica is a human pathogen that causes widespread morbidity and mortality. (scielo.org.co)
Diagnosis4
- Evaluation of a new single-tube multiprobe real-time PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar. (uptodate.com)
- A total of 51 E. histolytica and 39 E. dispar positive samples was detected by the multiprobe real-time PCR compared to 39 and 22 by routine nested PCR diagnosis. (uptodate.com)
- When checking for a misdiagnosis of Entamoeba histolytica or confirming a diagnosis of Entamoeba histolytica, it is useful to consider what other medical conditions might be possible misdiagnoses or other alternative conditions relevant to diagnosis. (rightdiagnosis.com)
- Use of the E. histolytica lectin for diagnosis of ALA has been well reported by researchers and is being used in commercialized kits. (asm.org)
Enteric protozoan1
- Entamoeba histolytic is an enteric protozoan that infects 10% of the world's population and is one of the following leading parasitic causes of death worldwide. (grantome.com)
Strains2
- DNA hybridizations showed that the gene was specific to E. histolytica since the cDNA probe reacted with DNA from four axenic strains of E. histolytica but did not react with DNA from Entamoeba invadens, Acanthamoeba castellanii, or Trichomonas vaginalis. (pnas.org)
- In order to determine the extent of genetic diversity among Entamoeba strains leading to different phenotypes, we hypothesized that the virulence may be linked to genotype. (omicsonline.org)
Antibodies4
- Purified fusion protein was used to generate 22 monoclonal antibodies (mAbs) and a mouse polyclonal antiserum specific for the E. histolytica portion of the fusion protein. (pnas.org)
- This blood test tells your healthcare provider whether you have antibodies in your blood to the parasite Entamoeba histolytica. (staywellsolutionsonline.com)
- If you have been infected with E. histolytica, your immune system may make these antibodies. (staywellsolutionsonline.com)
- If antibodies to E. histolytica are found, they are measured in units called titers. (staywellsolutionsonline.com)
Microscopy3
- PCR was found to be significantly more sensitive than microscopy or culture, as all samples positive by microscopy and 22 out of 25 (88%) samples positive by culture were also positive by PCR, but PCR revealed a considerable number of additional E. histolytica- or E. dispar -positive samples. (asm.org)
- Note: The test will only be performed following a positive microscopy for E. histolytica/dispar on an SAF preserved specimen. (publichealthontario.ca)
- Microscopy cannot differentiate between the virulent E. histolytica and the non-virulent E. dispar which never invades or causes a serological response. (parasite.org.au)
Asymptomatic4
- Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. (hindawi.com)
- However, four out of five E. histolytica infections remain asymptomatic. (jcvi.org)
- Inf ection with E. histolytica may be asymptomatic or cause intestinal or extraintestinal disease. (antimicrobe.org)
- Asymptomatic intestinal carriage of E. histolytica should not be reported. (cdc.gov)
Causative1
- Here, we identify functional heterotrimeric G-protein subunits in Entamoeba histolytica, the causative agent of amoebic colitis. (scienceexchange.com)
Clinical2
- To assess different laboratory methods for the identification of Entamoeba histolytica in clinical samples. (bmj.com)
- Multisite clinical evaluation of a rapid test for Entamoeba histolyticain stool. (elisakits.co.uk)
Colitis2
- Previously we catalogued the gene expression profile of E. histolytica associated with amebic colitis in the murine model ( 27 ). (pubmedcentralcanada.ca)
- However, occasionally E. histolytica penetrates the intestinal mucosa, which leads to ulcerative colitis or it disseminates to other organs, most commonly to the liver, where it induces abscess formation. (biomedcentral.com)
Gene2
- We have assigned putative function to 3,788 proteins (46% of the predicted proteome) based on the annotation of predicted gene families, and have identified 58 protein families of five or more members that share no homology with known proteins and thus could be entamoeba specific. (pubmedcentralcanada.ca)
- Our group has recently explored RNAi to knock down gene-specific expression in the protozoan parasite Entamoeba histolytica, through delivery of small interfering RNA (siRNA) oligonucleotides by the soaking approach. (pasteur.fr)
Pathogen4
- E. histolytica is also recognized as an emerging sexually transmissible pathogen, especially in male homosexual relations, causing outbreaks in non-endemic regions. (wikipedia.org)
- Entamoeba histolytica is a deep-branching eukaryotic pathogen. (asm.org)
- These studies have major implications for interactions between E. histolytica and the immune system and also reveal a novel strategy for immune evasion by a pathogen. (asm.org)
- The faecal-oral spread protozoan parasite Entamoeba histolytica is an important human pathogen. (biomedcentral.com)
Stool samples3
- Because E. histolytica is not always found in every stool sample, you may be asked to submit several stool samples from several different days. (emedicinehealth.com)
- My portion of the work involved the use of Entamoeba histolytica DNA collected from stool samples of patients at the ICDDR,B hospital and Mirpur cohort. (oxy.edu)
- You may have 1 or more stool samples tested to look for E. histolytica. (staywellsolutionsonline.com)
Large intestine1
- Coloured scanning electron micrograph (SEM) of Entamoeba histolytica amoebae (blue) invading the lining of the large intestine (colon). (sciencephoto.com)
Parasite entamoeba1
- These adhere to epithelial parasite Entamoeba histolytica (a biodefense category B patho- cells through interaction of galactose and N-acetyl-D- gen), is responsible for ~50 million infections annually worldwide, galactosamine (Gal/GalNAc)-specific lectin with host Gal/GalNAc- causes traveler's diarrhea, and disproportionately affects disad- 1,2 containing glycoconjugates. (deepdyve.com)
Feces2
- Puts anything into their mouth that has touched the feces (poop) of a person who is infected with E. histolytica . (emedicinehealth.com)
- Amplification of ameba DNA fragments by PCR has been proven to constitute a sensitive and specific method to detect E. histolytica or E. dispar from human feces ( 1 , 5 , 14 , 21 , 30 ). (asm.org)
Lectin4
- E. histolytica has a lectin that binds to galactose and N-acetylgalactosamine sugars on the surface of the epithelial cells, The lectin normally is used to bind bacteria for ingestion. (wikipedia.org)
- The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa surface lectin of the amoebae. (pnas.org)
- From the matrix-assisted laser desorption ionization-two-stage time of flight (MALDI-TOF/TOF) analysis, the proteins were identified as heavy subunits of E. histolytica lectin and E. histolytica pyruvate phosphate dikinase, respectively. (asm.org)
- These 14 positive stools were analyzed with an ELISA that detects Gal/GalNAc lectin antigen and can distinguish between E. histolytica and E. dispar. (elsevier.com)
ELISA2
- Analyses of four types of isoenzymes, molecular methods and ELISA tests of lectins distinguishes Entamoeba histolytica from E. dispar. (parasite.org.au)
- Human Entamoeba histolytica Ag ELISA kit is intended for measuring in-vitro quantitative levels of entamoeba histolytica antigen using faecal samples. (elisakits.co.uk)
Ingestion1
- E histolytica is predominately transmitted through the ingestion of the cystic form (i.e. the infective stage) of the protozoa. (elisakits.co.uk)