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Entamoeba histolyticaEntamoebaEntamoebiasisDysentery, AmebicLiver Abscess, AmebicTrophozoitesAmebicidesAmebiasisProtozoan ProteinsIntestinal Diseases, ParasiticProtozoan InfectionsDNA, ProtozoanFecesGiardia lambliaAntigens, ProtozoanGenome, ProtozoanCysteine ProteasesLectinsGenes, ProtozoanAcetylgalactosamineParasitologyAntibodies, ProtozoanDientamoebaBlastocystis hominisAntiprotozoal AgentsGerbillinaeParasitesMolecular Sequence DataEndolimaxMetronidazoleGiardiasisGiardiaGalactoseProtozoan VaccinesGalectinsLiver AbscessAmino Acid SequenceIodoquinolAdhesivenessBangladeshSerine O-AcetyltransferaseHost-Parasite InteractionsPyruvate SynthaseTrichomonasSuppurationDysenteryMaterial Safety Data SheetsAccess to InformationGastroenterologyBibliometricsPeriodicals as TopicJournal Impact Factor
Entamoeba histolytica: A species of parasitic protozoa causing ENTAMOEBIASIS and amebic dysentery (DYSENTERY, AMEBIC). Characteristics include a single nucleus containing a small central karyosome and peripheral chromatin that is finely and regularly beaded.Entamoeba: A genus of ameboid protozoa characterized by the presence of beaded chromatin on the inner surface of the nuclear membrane. Its organisms are parasitic in invertebrates and vertebrates, including humans.Entamoebiasis: Infection with amoebae of the genus ENTAMOEBA. Infection with E. histolytica causes DYSENTERY, AMEBIC and LIVER ABSCESS, AMEBIC.Dysentery, Amebic: DYSENTERY caused by intestinal amebic infection, chiefly with ENTAMOEBA HISTOLYTICA. This condition may be associated with amebic infection of the LIVER and other distant sites.Liver Abscess, Amebic: Single or multiple areas of PUS due to infection by any ameboid protozoa (AMEBIASIS). A common form is caused by the ingestion of ENTAMOEBA HISTOLYTICA.Trophozoites: Cells or feeding stage in the life cycle of sporozoan protozoa. In the malarial parasite, the trophozoite develops from the MEROZOITE and then splits into the SCHIZONT. Trophozoites that are left over from cell division can go on to form gametocytes.Amebicides: Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal.Amebiasis: Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.Protozoan Proteins: Proteins found in any species of protozoan.Intestinal Diseases, Parasitic: Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.Protozoan Infections: Infections with unicellular organisms formerly members of the subkingdom Protozoa.DNA, Protozoan: Deoxyribonucleic acid that makes up the genetic material of protozoa.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Giardia lamblia: A species of parasitic EUKARYOTES that attaches itself to the intestinal mucosa and feeds on mucous secretions. The organism is roughly pear-shaped and motility is somewhat erratic, with a slow oscillation about the long axis.Antigens, Protozoan: Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.Genome, Protozoan: The complete genetic complement contained in a set of CHROMOSOMES in a protozoan.Cysteine Proteases: A subclass of peptide hydrolases that depend on a CYSTEINE residue for their activity.Lectins: Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.Genes, Protozoan: The functional hereditary units of protozoa.Acetylgalactosamine: The N-acetyl derivative of galactosamine.Parasitology: The study of parasites and PARASITIC DISEASES.Antibodies, Protozoan: Immunoglobulins produced in a response to PROTOZOAN ANTIGENS.Dientamoeba: A genus of minute EUKARYOTES that are characterized by the preponderance of binucleate over uninucleate forms, the presence of several distinct granules in the karyosome, and the lack of a cystic stage. It is parasitic in the large intestine of humans and certain monkeys.Blastocystis hominis: A species of parasitic protozoa found in the intestines of humans and other primates. It was classified as a yeast in 1912. Over the years, questions arose about this designation. In 1967, many physiological and morphological B. hominis characteristics were reported that fit a protozoan classification. Since that time, other papers have corroborated this work and the organism is now recognized as a protozoan parasite of humans causing intestinal disease with potentially disabling symptoms.Antiprotozoal Agents: Substances that are destructive to protozoans.Gerbillinae: A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.Parasites: Invertebrate organisms that live on or in another organism (the host), and benefit at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Endolimax: A genus of ameboid protozoa found in the intestines of vertebrates and invertebrates.Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).Giardiasis: An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA LAMBLIA. It is spread via contaminated food and water and by direct person-to-person contact.Giardia: A genus of flagellate intestinal EUKARYOTES parasitic in various vertebrates, including humans. Characteristics include the presence of four pairs of flagella arising from a complicated system of axonemes and cysts that are ellipsoidal to ovoidal in shape.Galactose: An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.Protozoan Vaccines: Suspensions of attenuated or killed protozoa administered for the prevention or treatment of infectious protozoan disease.Galectins: A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.Liver Abscess: Solitary or multiple collections of PUS within the liver as a result of infection by bacteria, protozoa, or other agents.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Iodoquinol: One of the halogenated 8-quinolinols widely used as an intestinal antiseptic, especially as an antiamebic agent. It is also used topically in other infections and may cause CNS and eye damage. It is known by very many similar trade names world-wide.Adhesiveness: A property of the surface of an object that makes it stick to another surface.BangladeshSerine O-Acetyltransferase: An enzyme that catalyzes the conversion of L-SERINE to COENZYME A and O-acetyl-L-serine, using ACETYL-COA as a donor.Host-Parasite Interactions: The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.Pyruvate Synthase: A ferredoxin-containing enzyme that catalyzes the COENZYME A-dependent oxidative decarboxylation of PYRUVATE to acetyl-COENZYME A and CARBON DIOXIDE.Trichomonas: A genus of parasitic flagellate EUKARYOTES distinguished by the presence of four anterior flagella, an undulating membrane, and a trailing flagellum.Suppuration: A pathologic process consisting in the formation of pus.Dysentery: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.Material Safety Data Sheets: Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures.Access to Information: Individual's rights to obtain and use information collected or generated by others.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.

Hsp60 is targeted to a cryptic mitochondrion-derived organelle ("crypton") in the microaerophilic protozoan parasite Entamoeba histolytica. (1/861)

Entamoeba histolytica is a microaerophilic protozoan parasite in which neither mitochondria nor mitochondrion-derived organelles have been previously observed. Recently, a segment of an E. histolytica gene was identified that encoded a protein similar to the mitochondrial 60-kDa heat shock protein (Hsp60 or chaperonin 60), which refolds nuclear-encoded proteins after passage through organellar membranes. The possible function and localization of the amebic Hsp60 were explored here. Like Hsp60 of mitochondria, amebic Hsp60 RNA and protein were both strongly induced by incubating parasites at 42 degreesC. 5' and 3' rapid amplifications of cDNA ends were used to obtain the entire E. histolytica hsp60 coding region, which predicted a 536-amino-acid Hsp60. The E. histolytica hsp60 gene protected from heat shock Escherichia coli groEL mutants, demonstrating the chaperonin function of the amebic Hsp60. The E. histolytica Hsp60, which lacked characteristic carboxy-terminal Gly-Met repeats, had a 21-amino-acid amino-terminal, organelle-targeting presequence that was cleaved in vivo. This presequence was necessary to target Hsp60 to one (and occasionally two or three) short, cylindrical organelle(s). In contrast, amebic alcohol dehydrogenase 1 and ferredoxin, which are bacteria-like enzymes, were diffusely distributed throughout the cytosol. We suggest that the Hsp60-associated, mitochondrion-derived organelle identified here be named "crypton," as its structure was previously hidden and its function is still cryptic.  (+info)

Prevalence of intestinal parasite infections with special reference to Entamoeba histolytica on the island of Bioko (Equatorial Guinea). (2/861)

The prevalence of intestinal parasitic infections was assessed (1993 through 1995) among two different groups of persons on the island of Bioko, Equatorial Guinea. In the first group, parasitologic examinations were performed on stool specimens from a household-based sample of 557 dwellers from the rural area of the island. In the second group, 1,633 inpatients and outpatients at the General Hospital of Malabo (the capital of the country) were studied. All age groups were represented in both groups. The average prevalence of the most common protozoan and helminthic intestinal infections in rural and urban areas, respectively, was as follows: Entamoeba histolytica/E. dispar (14.9% and 32.7%, respectively), Giardia lamblia (7.2% and 8.6%), Ascaris lumbricoides (45.8% and 31.4%), and Trichuris trichiura (25.7% and 36.4%). Seventy-nine sera from patients with amebic liver abscess (suspected by ultrasonography) were studied by an immunohemagglutination assay, with 44 (56%) showing anti-E. histolytica titers > or = 1:32. Of these 79 sera, 71 were studied by an enzyme immunoassay, 86% of which were positive with titers > or = 1:64. This study showed that parasitic infections in Equatorial Guinea represent a major health problem.  (+info)

Characterization of YS-27, an axenic Korean strain of Entamoeba histolytica. (3/861)

Characterization of YS-27, an axenic Entamoeba strain, was performed by three different laboratory methods. Zymodeme analysis using starch gel electrophoresis and PCR with species-specific primers showed that YS-27 is a pathogenic Entamoeba which belongs to the group II zymodeme. Pathogenicity of YS-27 was further confirmed by observing the formation of liver abscess in Mongolian gerbils. These results showed that YS-27 is E. hisolytica.  (+info)

The TATA-box binding protein of Entamoeba histolytica: cloning of the gene and location of the protein by immunofluorescence and confocal microscopy. (4/861)

A 309 bp DNA fragment from Entamoeba histolytica was amplified by PCR using primers derived from the Acanthamoeba castellanii consensus TATA-box binding protein amino acid sequence. The amplified fragment was used to isolate cDNA and genomic DNA clones containing an ORF encoding the complete E. histolytica TATA-box binding protein (Ehtbp, 702 bp, 234 aa, molecular mass 26 kDa). The EhTBP functional domain showed 55% sequence identity to that of Homo sapiens, 54% to A. castellanii and 37% to Plasmodium falciparum TBPs. In Southern blot experiments we detected a single Ehtbp band, which was transcribed as a 1.3 kb mRNA containing a 420 nt 5' untranslated region. However, the probe hybridized with the 0.8 and 1.5 Mb chromosomes, suggesting that this sequence is diploid. In situ PCR assays showed two signals in 95% of trophozoites, one located in the nucleus and another in EhkO, the novel DNA-containing organelle recently reported. The recombinant E. histolytica TATA-box binding protein was expressed in Escherichia coli. Antibodies against it recognized two proteins of 26 and 29 kDa in E. histolytica nuclear extracts. Confocal microscopy immunofluorescence analysis located the protein in both the nucleus and EhkO.  (+info)

Preparation of recombinant human monoclonal antibody Fab fragments specific for Entamoeba histolytica. (5/861)

Genes coding for human antibody Fab fragments specific for Entamoeba histolytica were cloned and expressed in Escherichia coli. Lymphocytes were separated from the peripheral blood of a patient with an amebic liver abscess. Poly(A)+ RNA was isolated from the lymphocytes, and then genes coding for the light chain and Fd region of the heavy chain were amplified by a reverse transcriptase PCR. The amplified DNA fragments were ligated with a plasmid vector and were introduced into Escherichia coli. Three thousand colonies were screened for the production of antibodies to E. histolytica HM-1:IMSS by an indirect fluorescence-antibody (IFA) test. Lysates from five Escherichia coli clones were positive. Analysis of the DNA sequences of the five clones showed that three of the five heavy-chain sequences and four of the five light-chain sequences differed from each other. When the reactivities of the Escherichia coli lysates to nine reference strains of E. histolytica were examined by the IFA test, three Fab fragments with different DNA sequences were found to react with all nine strains and another Fab fragment was found to react with seven strains. None of the four human monoclonal antibody Fab fragments reacted with Entamoeba dispar reference strains or with other enteric protozoan parasites. These results indicate that the bacterial expression system reported here is effective for the production of human monoclonal antibodies specific for E. histolytica. The recombinant human monoclonal antibody Fab fragments may be applicable for distinguishing E. histolytica from E. dispar and for use in the serodiagnosis of amebiasis.  (+info)

Down regulation of Entamoeba histolytica virulence by monoxenic cultivation with Escherichia coli O55 is related to a decrease in expression of the light (35-kilodalton) subunit of the Gal/GalNAc lectin. (6/861)

Entamoeba histolytica virulence is related to a number of amebic components (lectins, cysteine proteinases, and amebapore) and host factors, such as intestinal bacterial flora. Trophozoites are selective in their interactions with bacteria, and the parasite recognition of glycoconjugates plays an important role in amebic virulence. Long-term monoxenic cultivation of pathogenic E. histolytica trophozoites, strains HK-9 or HM-1:IMSS, with Escherichia coli serotype O55, which binds strongly to the Gal/GalNAc amebic lectin, markedly reduced the trophozoites' adherence and cytopathic activity on cell monolayers of baby hamster kidney (BHK) cells. Specific probes prepared from E. histolytica lectin genes as well as antibodies directed against the light (35-kDa) and heavy (170-kDa) subunits of the Gal/GalNAc lectin revealed a decrease in the transcription and expression of the light subunit in trophozoites grown monoxenically with E. coli O55. This effect was not observed when E. histolytica was grown with E. coli 346, a mannose-binding type I pilated bacteria. Our results suggest that the light subunit of the amebic lectin is involved in the modulation of parasite adherence and cytopathic activity.  (+info)

Chitinase secretion by encysting Entamoeba invadens and transfected Entamoeba histolytica trophozoites: localization of secretory vesicles, endoplasmic reticulum, and Golgi apparatus. (7/861)

Entamoeba histolytica, the protozoan parasite that phagocytoses bacteria and host cells, has a vesicle/vacuole-filled cytosol like that of macrophages. In contrast, the infectious cyst form has four nuclei and a chitin wall. Here, anti-chitinase antibodies identified hundreds of small secretory vesicles in encysting E. invadens parasites and in E. histolytica trophozoites overexpressing chitinase under an actin gene promoter. Abundant small secretory vesicles were also identified with antibodies to the surface antigen Ariel and with a fluorescent substrate of cysteine proteinases. Removal of an N-terminal signal sequence directed chitinase to the cytosol. Addition of a C-terminal KDEL peptide, identified on amebic BiP, retained chitinase in a putative endoplasmic reticulum, which was composed of a few vesicles of mixed sizes. A putative Golgi apparatus, which was Brefeldin A sensitive and composed of a few large, perinuclear vesicles, was identified with antibodies to ADP-ribosylating factor and to epsilon-COP. We conclude that the amebic secretory pathway is similar to those of other eukaryotic cells, even if its appearance is somewhat different.  (+info)

Intestinal mucins in colonization and host defense against pathogens. (8/861)

Intestinal mucins are key components of the first line of host defense against intestinal pathogens. These large glycoconjugates secreted by specialized exocrine goblet cells form viscous gels that trap microorganisms and irritants and limit their diffusion to the intestinal epithelium. Moreover, they allow for colonization by indigenous bacterial flora that prevents attachment of pathogenic microbes. The interaction between microbes and mucins involves mucin carbohydrate side chains and microbial adhesin molecules. Certain microorganisms and disease states may alter mucin biochemistry or expression. Although these alterations most likely contribute to disease processes, the full impact of these phenomena are still unclear. The development of mucin-secreting cell lines has facilitated the study of mucin biology and aided our understanding of mucin-microbial interactions.  (+info)

Category:Entamoeba histolytica - Wikimedia CommonsCategory:Entamoeba histolytica - Wikimedia Commons
Entamoeba histolytica (es); Entamoeba histolytica (hu); Entamoeba histolytica (eu); Entamoeba histolytica (ast); Entamoeba histolytica (ca); Entamoeba histolytica (de); Entamoeba histolytica (ga); Дизентерична амеба (sr-ec); 溶组织内阿米巴 (zh); Entamoeba histolytica (da); Entamoeba histolytica (tr); 溶組織內阿米巴 (zh-hk); Entamoeba histolytica (sv); Entamoeba histolytica (uk); Entamoeba histolytica (la); 溶組織內阿米巴 (zh-hant); 溶组织内阿米巴 (zh-cn); Suoliameba (fi); Дизентерия амебасы (kk); měňavka úplavičná (cs); Entamoeba histolytica (it); Entamoeba histolytica (fr); Entamoeba histolytica (nl); Dizenteriya amyobasi (uz); Entaméba istulìtica (eml); Entamoeba histolytica (en); Դիզենթերիայի ամեոբա (hy); Entamoeba histolytica (vi); дизентерийная амёба (ru); Entamoeba histolytica (pt); انتاموبا هیستولیتیکا (fa); 溶組織內阿米巴 (zh-tw); Entamoeba histolytica (nb); ...
Investigation on Entamoeba histolytica infection in diarrhea patients from general hospitals in Shanghai City] | GHDxInvestigation on Entamoeba histolytica infection in diarrhea patients from general hospitals in Shanghai City] | GHDx
Zhang X, He Y, Wang Z, Zhang Y, Zhu Q, Jiang S, Li Y, Cheng Y, Yin M. [Investigation on Entamoeba histolytica infection in diarrhea patients from general hospitals in Shanghai City]. Chin J Schistosomiasis Control. 2015; 27(6): 600-3 ...
Diversity of clinical isolates of Entamoeba histolytica in Japan<...Diversity of clinical isolates of Entamoeba histolytica in Japan<...
TY - JOUR. T1 - Diversity of clinical isolates of Entamoeba histolytica in Japan. AU - Nozaki, Tomoyoshi. AU - Kobayashi, Seiki. AU - Takeuchi, Tsutomu. AU - Haghighi, Ali. PY - 2006/2. Y1 - 2006/2. N2 - In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. Here we briefly summarize epidemiology of amebiasis in Japan. We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model.. AB - In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. Here we briefly ...
PLOS Neglected Tropical Diseases: Increased Risk for Entamoeba histolytica Infection and Invasive Amebiasis in HIV Seropositive...PLOS Neglected Tropical Diseases: Increased Risk for Entamoeba histolytica Infection and Invasive Amebiasis in HIV Seropositive...
Author SummaryEntamoeba histolytica, morphologically identical to but genetically different from E. dispar and E. moshkovskii, is the causative agent of amebiasis. Recently there have been reports of increased risk for amebiasis among men who have sex with men (MSM) due to oral-anal sexual contact in several developed countries. In this longitudinal follow-up study, the incidence of amebiasis was determined among HIV-infected patients using serological and specific amebic antigen assays. DNA extracted from stool samples containing E. histolytica were analyzed by PCR, sequenced, and compared. Clinical manifestations and treatment response of invasive amebiasis in HIV-infected patients were reviewed. The results demonstrated that HIV-infected MSM were at significantly higher risk of amebiasis than patients from other risk groups. Clustering of E. histolytica isolates by sequencing analyses from geographically unrelated patients suggested person-to-person transmission. Despite immunosuppression, amebic
Entamoeba histolytica Cysteine Proteinases Disrupt the Polymeric Structure of Colonic Mucin and Alter Its Protective Function |...Entamoeba histolytica Cysteine Proteinases Disrupt the Polymeric Structure of Colonic Mucin and Alter Its Protective Function |...
The majority of individuals infected with E. histolytica are asymptomatic carriers, but invasion does occur in a small percentage of those afflicted with the parasite (33). In order for invasion to occur, the parasite must overcome the protective mucous layer lining the colon. Histopathology studies of the human colon and rectum have revealed that the mucous layer lining these regions is separated into two striated layers. The outer layer contains most of the bacterial and fecal contents, and the inner layer contains little to no bacteria (21). These observations imply that mucin plays a role in establishing a clear barrier between luminal contents, including pathogens, and the colonic epithelium.. Previous studies have indicated that E. histolytica cellular lysates and SPs were ineffective at degrading human colonic mucin, and it was suggested that the parasite may cause a mechanical depletion of the mucous blanket by inducing goblet cell hypersecretion prior to invasion (31). In this study, we ...
Nitro BlueTetrazolium Chloride and Phagocytic Activity for Entamoeba Histolytica | Al-Mustansiriyah Journal of...Nitro BlueTetrazolium Chloride and Phagocytic Activity for Entamoeba Histolytica | Al-Mustansiriyah Journal of...
photometry Entamoeba histolytica parasite induces apoptosis in host cells by for step(first)adherence to the host cell surface, (second) contact-subordinate cell killing, (third) start of phagocytosis so NBT used to determine percentage of phagocytosis for Entamoeba. Methods: This study was performed on 80 male they were divided to 25 control subjects and 55 subjects were diagnosed to be infected by Entamoeba histolytica at urban and rural areas in wassit province. Entamoeba histolytica and NBT were evaluated. Results: The results showed a significant difference between the two groups (10.96±2.745) for control group and 19.63±3.617 in patients group with confidence interval (7.056-10.29). P.value P,0.001 ratio minimum number was 7%, 13% for the control and patient groups. Conclusion: There were a significant increase in phagocytic activity of polymorph neaucler neutrophils (PMNs) for reduction of NBT stain. ...
Trophozoites of Entamoeba histolytica express a CD59-like molecule in human colon - Semantic ScholarTrophozoites of Entamoeba histolytica express a CD59-like molecule in human colon - Semantic Scholar
In vitro studies have proved the presence of epitopes of CD59 in the surface of trophozoites of Entamoeba histolytica (E. histolytica). However, it has not been proved if CD59 molecules are expressed in the surface during the trophozoites tissue invasion. The aim of the present study was to determine whether the complement-regulatory protein CD59 is present on trophozoites of E. histolytica in human colon. Eleven specimens of amoebic colitis were studied by immunohistochemistry and electron microscopy techniques with a monoclonal antibody against human CD59 molecule. Our results show that a CD59-like molecule is expressed in trophozoites of E. histolytica found in colonic amebic lesions. Also, a CD59-like molecule was detected by western blot analysis in whole lysate of E. histolytica as well as on the plasma membrane by immunocytochemistry. These results suggest that E. histolytica can use CD59-like protein against the lytic action of membrane attack complex.
Point-of-Care Diagnostic Test for Entamoeba histolytica Cysts - Joel HerbeinPoint-of-Care Diagnostic Test for Entamoeba histolytica Cysts - Joel Herbein
The NIAID Category B priority pathogen Entamoeba histolytica is a public health threat, especially as a cause of diarrhea in travelers to and immigrants from en...
Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human...Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human...
TY - JOUR. T1 - Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica. AU - Nurkanto, Arif. AU - Jeelani, Ghulam. AU - Yamamoto, Takehiro. AU - Hishiki, Takako. AU - Naito, Yoshiko. AU - Suematsu, Makoto. AU - Hashimoto, Tetsuo. AU - Nozaki, Tomoyoshi. PY - 2018/11/30. Y1 - 2018/11/30. N2 - Coenzyme A (CoA) is an essential cofactor for numerous cellular reactions in all living organisms. In the protozoan parasite Entamoeba histolytica, CoA is synthesized in a pathway consisting of four enzymes with dephospho-CoA kinase (DPCK) catalyzing the last step. However, the metabolic and physiological roles of E. histolytica DPCK remain elusive. In this study, we took biochemical, reverse genetic, and metabolomic approaches to elucidate role of DPCK in E. histolytica. The E. histolytica genome encodes two DPCK isotypes (EhDPCK1 and EhDPCK2). Epigenetic gene silencing of Ehdpck1 and Ehdpck2 ...
Medical Chemical Corporation: Para-siteMedical Chemical Corporation: Para-site
Without confirmation using the specific immunoassay to detect the true pathogen, E. histolytica, the report must indicate: Entamoeba histolytica/E. dispar group (indicate cysts and/or trophozoites); make sure your clients know what this report means in terms of pathogens/nonpathogen (based on trophozoite morphology). If cysts are seen containing a single nucleus and the typical inclusion body, then the organism could be identified to the correct species: Entamoeba polecki. Report Comment: Submit a fresh stool if you want confirmation of the true pathogen (Entamoeba histolytica). The laboratory will then test the fresh stool (fresh, frozen, some acceptable in Cary-Blair) for the presence of the true pathogen, Entamoeba histolytica, antigen. If confirmation of E. histolytica is not performed, then the physician will usually treat if the patient is symptomatic.. Treatment: ...
Entamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase FamilyEntamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase Family
Author SummaryThere is a highly ordered process by which the parasite Entamoeba histolytica interacts with human cells. Adherence via a parasite lectin is followed in seconds by killing, with only the corpse and not a living cell ingested by the ameba. This process is so central to pathogenesis that clinicians use the presence of ingested erythrocytes to identify E. histolytica and distinguish it from harmless commensal amebae of the gut. We hypothesized that identification of molecules involved in the ingestion of the corpse might provide insight into how amebae cause colitis. We identified a member of the transmembrane kinase family as an early component of the phagosome. Inhibition of this kinase blocked red cell ingestion and prevented amebae from colonizing and invading the gut. There was no impact on dominant-negative parasites to cause liver abscess, suggesting the pathogenesis program differs between anatomic sites. Future studies of the transmembrane kinanse in erythrophagocytosis may provide
Entamoeba coli - WikipediaEntamoeba coli - Wikipedia
Entamoeba coli is a non-pathogenic species of Entamoeba that frequently exists as a commensal parasite in the human gastrointestinal tract. E. coli (not to be confused with the bacterium Escherichia coli) is important in medicine because it can be confused during microscopic examination of stained stool specimens with the pathogenic Entamoeba histolytica. This amoeba does not move much by the use of its pseudopod, and creates a "sur place (non-progressive) movement" inside the large intestine. Usually, the amoeba is immobile, and keeps its round shape. This amoeba, in its trophozoite stage, is only visible in fresh, unfixed stool specimens. Sometimes the Entamoeba coli have parasites as well. One is the fungus Sphaerita spp. This fungus lives in the cytoplasm of the E. coli. While this differentiation is typically done by visual examination of the parasitic cysts via light microscopy, new methods using molecular biology techniques have been developed. The scientific name of the amoeba, E. coli, ...
Entamoeba histolyticaEntamoeba histolytica
This page includes the following topics and synonyms: Entamoeba histolytica, E. histolytica, Amebiasis, Amoebiasis, Amebic Dysentery, Ameboma, Amoeba Histolytica Dysentery.
Entamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo LibraryEntamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo Library
Light microscope footage of Entamoeba histolytica protozoa. E. histolytica is a parasite that causes amoebic dysentery in humans. Seen here is the active trophozoite form of the parasite, which lives in the human intestines, causing ulceration and symptoms including diarrhoea, cramps, fever and weight loss. If untreated, the amoeba can move to the liver and other organs, and the infection can prove fatal in some cases. The disease is endemic in regions with poor sanitation. The parasites are passed in faeces, and can survive outside the body as long-lasting cysts, which revert to the active trophozoite stage when ingested. Proper hygiene aids prevention of the disease. Treatment is with antimicrobial drugs. The trophozoites can reach 20 microns in diameter. This is the Human Mexico 1 (HM-1) strain. - Stock Video Clip K003/8943
Molecules | Free Full-Text | Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican...Molecules | Free Full-Text | Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican...
Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries. Because of the side-effects and the resistance that pathogenic protozoa build against the standard antiparasitic drugs, e.g., metronidazole, much recent attention has been paid to plants used in traditional medicine around the world in order to find new antiprotozoal agents. We collected 32 plants used in Northeast Mexican traditional medicine and the methanolic extracts of these species were screened for antiprotozoal activity against E. histolytica trophozoites using in vitro tests. Only 18 extracts showed a significant inhibiting activity and among them six plant extracts showed more than 80% growth inhibition against E. histolytica at a concentration of 150 µg/mL and the IC50 values of these extracts were determined. Lippia graveolens Kunth and Ruta chalepensis Pers. showed the more significant antiprotozoal activity (91
REGULATION OF THE LIPID RAFT LOCALIZATION OF THE GAL/GALNAC LECTIN, AN by Amanda Goldston"REGULATION OF THE LIPID RAFT LOCALIZATION OF THE GAL/GALNAC LECTIN, AN" by Amanda Goldston
Lipid rafts, sterol- and sphingolipid-rich membrane microdomains, have been shown to control virulence in a variety of parasites including Entamoeba histolytica, an intestinal parasite that causes dysentery and liver abscess. Parasite cell surface receptors, such as the Gal/GalNAc lectin, facilitate attachment to host cells and extracellular matrix. The Gal/GalNAc lectin binds to galactose or N-acetylgalactosamine residues on host components, and is composed of heavy (Hgl), intermediate (Igl), and light (Lgl) subunits. Although Igl is constitutively localized to lipid rafts, Hgl and Lgl transiently associate with this compartment in a cholesterol-dependent fashion. Exposure to bonafide Gal/GalNAc lectin ligands is associated with enrichment of the subunits in rafts. Direct lectin-ligand interactions and sufficient levels of both PIP2 and calcium were shown to be necessary for lectin enrichment in rafts. Additionally, an initial analysis of both post-translational modifications and protein interactions
Studies on the Pathogenicity of Various Strains of Entamoeba Histolytica after Prolonged Cultivation, with Observations on...Studies on the Pathogenicity of Various Strains of Entamoeba Histolytica after Prolonged Cultivation, with Observations on...
Summary Attempts to utilize the rat cecal scoring technique of Neal to measure the invasiveness of strains of Entamoeba histolytica gave inconsistent results when Sherman strain rats were used. Results with Wistar rats were more consistent. Two strains of E. histolytica, one in culture for 11 years and another in culture for 4 years, were still as highly infective and invasive as were four strains recently isolated from cases of symptomatic amebiasis. Strain F22 originally isolated from an amebic abscess of the brain showed diminished infectivity and invasiveness. Its infectivity and invasiveness were restored to a level comparable to recently isolated strains when organisms were passed rapidly through rats and culture.
Entamoeba histolytica Schaudinn ATCC ® 30015™Entamoeba histolytica Schaudinn ATCC ® 30015™
Entamoeba histolytica ATCC ® 30015™ Designation: HK-9 Isolation: Colonic biopsy from adult human male with amebic dysentery, Korea, (?)
Entamoeba histolytica Schaudinn ATCC ® 30015™Entamoeba histolytica Schaudinn ATCC ® 30015™
Entamoeba histolytica ATCC ® 30015™ Designation: HK-9 Isolation: Colonic biopsy from adult human male with amebic dysentery, Korea, (?)
The Cultivation of Endamoeba histolytica by Maurice E. Callender"The Cultivation of Endamoeba histolytica" by Maurice E. Callender
Endamoeba histolytica is the casual organism of the disease, amebiasis. Global distribution of high incidence makes this protozoan infection an enormous public health and economic problem. Cultural behavior and the ensuing search for effective chemotherapeutic agents has stimulated widespread interest in the parasitology and associated bacteriology of this organism.
Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite...Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite...
The DNA methylation status of the protozoan parasite Entamoeba histolytica was heretofore unknown. In the present study, we developed a new technique, based on the affinity of methylated DNA to 5-methylcytosine antibodies, to identify methylated DNA in this parasite. Ribosomal DNA and ribosomal DNA …
The American Journal of Tropical Medicine and Hygiene | Induced Division Synchrony in Entamoeba HistolyticaThe American Journal of Tropical Medicine and Hygiene | Induced Division Synchrony in Entamoeba Histolytica
Abstract Synchronous growth of axenic Entamoeba histolytica was induced by nutritional deprivation and/or hydroxyurea. Axenic amebae maintained in 2% serum culture medium for 17-25 hours and returned to complete TP-S-1 (10% serum) medium showed a single synchronous cycle with a mean division time of 8.8 hours and a synchrony index of 0.47. Exposure to 10 mM hydroxyurea for 20-26 hours induced a single synchronous cycle with a division time of 3.0 hours and a synchrony index of 0.85. Hydroxyurea was toxic to 56% of the cells in the culture. The control generation time in TP-S-1 medium was 14.8 hours. Cells maintained for 44 hours in a nucleotide-deficient medium followed by a 10 mM hydroxyurea treatment exhibited two synchronous cycles. The first cycle had a generation time of 5.0 hours, a division time of 2.2 hours, and a synchrony index of 0.84.
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Entamoeba histolytica is an intestinal protozoan parasite of humans that causes amebic colitis and amebic liver abscess: diseases associated with significant levels of morbidity and mortality worldwide [1]. The organism has a simple life cycle, existing as either the motile trophozoite or the infectious, hardy cyst form. Trophozoites of E. histolytica reside within the anaerobic confines of the human colon, lack mitochondria, derive energy from fermentation and reproduce by binary fission. E. histolytica trophozoites can be potent pathogens, possessing an armamentarium that includes a galactose-N-acetyl-galactosamine-binding lectin that mediates adherence to host cells, pore-forming proteins (amebapores) that can lyse bacteria or eukaryotic cells, cysteine proteinases that can cleave extracellular-matrix proteins and facilitate invasion into the colonic mucosa, and impressive phagocytic capabilities [1]. During the past three decades, the tools of molecular biology have greatly increased the ...
RIDASCREEN® Entamoeba histolytica IgG (en) - Clinical DiagnosticsRIDASCREEN® Entamoeba histolytica IgG (en) - Clinical Diagnostics
Infection with E. histolytica occurs orally with the intake of cysts. The vegetative form of the parasite develops from these cysts in the small intestine. This trophozoite multiplies and differentiates mostly in the colon. The clinical symptoms of an amebiasis are triggered by the invasion of parasites from the intestinal lumen into the mucous membrane of the colon. Diarrhea, dysentery or even ameboma are results of the invasion into the intestinal mucosa. If dissemination occurs, further complications can be liver abscesses, lung abscesses or in rare cases even brain abscesses, which can be fatal if left untreated. If an extraintestinal amebiasis was suspected, sonography should be the method of the choice. Since this method cannot always differentiate an abscess caused by E. histolytica from other abscesses or carcinoma, an antibody detection should be made to support other clinical findings. Antibodies are usually detectable with the beginning of the clinical symptoms. Due to the often ...
Amebiasis histolytica AntibodyAmebiasis histolytica Antibody
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References - Biology OnlineReferences - Biology Online
A short article about Entamoeba histolytica, an intestinal protozoan parasite of humans that causes amebic colitis and amebic liver abscess...
US-OH Training Position-ParasitologyUS-OH Training Position-Parasitology
Parasitology Postgraduate Research Participation Program A training position in the Oak Ridge Postgraduate Research Participation Program is available for a recent graduates specializing in parasitology. The successful candidate will pursue a full time research program on detection methodology for waterborne enteric protozoan parasites at the U.S. EPAs National Exposure Research Laboratory in Cincinnati, Ohio. Research training will include immunological and molecular methods of identification to species level of protozoans in environmental water samples. The candidate should have experience or knowledge in: maintaining enteric protozoan parasite cycles in animals, immunology, molecular biology, viability testing, and sophisticated light microscopic techniques (CSLM, DIC, etc.). Send resume and names and phone numbers of three references to: Dr. H.D. Alan Lindquist U.S. EPA 26 W. M.L. King Drive Cincinnati, OH 45268-1320 e-mail: lindquist.alan at epamail.epa.gov ...
Iraqi Academic Scientific Journals - IASJIraqi Academic Scientific Journals - IASJ
A total of 90 stool sample was collected from patients with gastroenteritis to detect adenovirus antigen among diarrhea cases. They were tested by general stool examination (GSE), rapid immunochromatographic test and Enzyme Linked Immunosorbent Assay (ELISA). GSE showed that adenovirus gastroenteritis infection resulted in non-bloody diarrhea, the existence of RBCs in 7% and Pus in 37% of the samples, Entamoeba histolytica trophozoite and cyst were seen in 3% and 2% of the samples respectively. The rapid test showed that 21% of samples were positive for rotavirus, 8% for adenovirus and 3% for astrovirus. Meanwhile, the ELISA test showed that adenovirus was positive in 9% of the samples. These findings established the evidence that adenovirus is significantly the second viral agent that cause gastroenteritis among children after rotavirus. Furthermore, it must be stated that rapid diagnostic methods are important for detection of adenovirus infection.. ...
Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts - Full Text View - ClinicalTrials.govIntestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts - Full Text View - ClinicalTrials.gov
HIV-infected persons who are men having sex with men (MSM) are prone to acquire invasive amebiasis. It would cast great threat for public health if the pathogens are spread by way of human to human transmission and food contamination.. From 2000 to 2004, we assessed the seroprevalence of Entamoeba histolytica infection using indirect hemagglutination antibody (IHA) assay among 667 HIV-infected persons (group 1), 1311 asymptomatic HIV-uninfected persons seeking anonymous HIV testing (group 2), 616 HIV-uninfected controls with gastrointestinal symptoms (diarrhea and/or liver abscess) seeking medical care (group 3), and 2500 healthy controls undergoing health check-up (group 4). An IHA titer greater than 128 was detected in 7.1% of group 1, 2.5% of group 2, 1.8% of group 3, and 0.1% of group 4 (p,0.0001). The highest seroprevalence (11.2%) was noted among HIV-infected persons who were MSM aged 30 to 39 years. Compared with persons with gastrointestinal symptoms, the adjusted odds ratio for having ...
Entamoeba histolytica: The Cause of Amoebiasis (November 22, 2017) | Global Water Pathogen ProjectEntamoeba histolytica: The Cause of Amoebiasis (November 22, 2017) | Global Water Pathogen Project
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LSHTM Research OnlineLSHTM Research Online
An important gap in our understanding of the epidemiology of amebiasis is what determines the outcome of Entamoeba histolytica infections. To investigate the possible existence of invasive and noninvasive strains as one factor, the ability to differentiate individual isolates of E. histolytica is necessary. Two new loci containing internal repeats, locus 1-2 and locus 5-6, have been isolated. Each contains a single repeat block with two types of related direct repeats arranged in tandem. Southern blot analysis suggests that both loci are multicopy and may themselves be arranged in tandem arrays. Three other previously reported, internally repetitive loci containing at least two repeat blocks each with one or more related repeat units were also investigated. PCR was used to study polymorphism at each of these loci, which was detected to various degrees in each case. Variation was seen in the total number of bands obtained per isolate and their sizes. Nucleotide sequence comparison of loci 1-2 and ...
Exploring The Short Interspersed Nuclear Elements For Genotyping Entamoeba Histolytica | 21192Exploring The Short Interspersed Nuclear Elements For Genotyping Entamoeba Histolytica | 21192
Enteric protozoa continue to be the most commonly encountered parasitic diseases and to cause significant morbidity and mortality throughout both developed and...
Characterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal InfectionCharacterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal Infection
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Beginilah Cara Mencegah Penyakit Amebiasis | Bersosial.comBeginilah Cara Mencegah Penyakit Amebiasis | Bersosial.com
Penyakit amebiasis merupakan infeksi parasit pada usus yang disebabkan oleh parasit Entamoeba histolytica atau disingkat E. Histolytica. Entamoeba...
LINEs and SINE-like elements of the protist Entamoeba histolytica. - PubMed - NCBILINEs and SINE-like elements of the protist Entamoeba histolytica. - PubMed - NCBI
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Expression of EhRAD54, EhRAD51, and EhBLM proteins during DNA repair by homologous recombination in Entamoeba histolytica |...Expression of EhRAD54, EhRAD51, and EhBLM proteins during DNA repair by homologous recombination in Entamoeba histolytica |...
Parasite international open-access, peer-reviewed, online journal publishing high quality papers on all aspects of human and animal parasitology
KEGG PATHWAY: Nucleotide excision repair - Entamoeba histolyticaKEGG PATHWAY: Nucleotide excision repair - Entamoeba histolytica
Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar ...
Entamoeba histolytica (sect) ih | Boreal ScienceEntamoeba histolytica (sect) ih | Boreal Science
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Entamoeba histolytica: Gene Expression Analysis of Cells Invading TissuesEntamoeba histolytica: Gene Expression Analysis of Cells Invading Tissues
The Scientific World Journal is a peer-reviewed, Open Access journal that publishes original research, reviews, and clinical studies covering a wide range of subjects in science, technology, and medicine. The journal is divided into 81 subject areas.
EHI 093910 - Histidine triad nucleotide-binding protein - Entamoeba histolytica - EHI 093910 gene & proteinEHI 093910 - Histidine triad nucleotide-binding protein - Entamoeba histolytica - EHI 093910 gene & protein
Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5monophosphoramidate (AMP-NH2), adenosine 5monophosphomorpholidate (AMP-morpholidate) and guanosine 5monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. May also function as scaffolding protein that mediates protein-protein interactions (By similarity).
Amebic liver abscess and circulating immune complexes of Entamoeba histolytica proteinsAmebic liver abscess and circulating immune complexes of Entamoeba histolytica proteins
An enzyme-linked immunosorbent assay (ELISA) has been developed to detect amebic antigen in polyethylene-glycol-precipitable circulating immune complexes. Seventy-nine percent of 191 patients with amebic liver abscesses and 46% of 26 Entamoeba histolytica cyst passers had positive tests. None of the samples from 43 apparently healthy controls, 8 patients with past amebic liver abscesses or 31 patients with Giardia lamblia infections were positive. One patient out of 32 with viral hepatitis and 1 patient out of 27 with intestinal tuberculosis had positive tests ...
Amebic dysentery synonyms, amebic dysentery antonyms - FreeThesaurus.comAmebic dysentery synonyms, amebic dysentery antonyms - FreeThesaurus.com
Synonyms for amebic dysentery in Free Thesaurus. Antonyms for amebic dysentery. 1 synonym for amebic dysentery: amoebic dysentery. What are synonyms for amebic dysentery?
Entamoeba histolytica | MSDSonlineEntamoeba histolytica | MSDSonline
MATERIAL SAFETY DATA SHEET - INFECTIOUS SUBSTANCES SECTION I - INFECTIOUS AGENT NAME: Entamoeba histolytica SYNONYM OR CROSS REFERENCE: Amebiasis, Amebic dysentery, Ameboma CHARACTERISTICS: Obligate parasite of human alimentary tract; possess both cyst (10-15 µm in diameter) and trophozoite forms; trophozoite (12-50 µm in diameter) are microaerophilic with a granular, vacuolated endoplasm and clear ectoplasm with pseudopods SECTION II - HEALTH HAZARD PATHOGENICITY: Approximately 90% of most infections are asymptomatic, only evidence may be seroconversion; debilitated, pregnant or immunocompromised individuals may develop an abrupt onset of fever, severe abdominal cramps, profuse bloody diarrhea and tenesmus; complications include massive hemorrhage, peritonitis, amebomas and liver abscesses EPIDEMIOLOGY: Worldwide distribution;10% of worlds population is infected with E. histolytica; stool survey in the US indicated that 5% of the population harbors E. histolytica; higher incidence in areas ...
Entamoeba - WikipediaEntamoeba - Wikipedia
Entamoeba is a genus of Amoebozoa found as internal parasites or commensals of animals. In 1875, Fedor Lösch described the first proven case of amoebic dysentery in St. Petersburg, Russia. He referred to the amoeba he observed microscopically as Amoeba coli; however it is not clear whether he was using this as a descriptive term or intended it as a formal taxonomic name. The genus Entamoeba was defined by Casagrandi and Barbagallo for the species Entamoeba coli, which is known to be a commensal organism. Löschs organism was renamed Entamoeba histolytica by Fritz Schaudinn in 1903; he later died, in 1906, from a self-inflicted infection when studying this amoeba. For a time during the first half of the 20th century the entire genus Entamoeba was transferred to Endamoeba, a genus of amoebas infecting invertebrates about which little is known. This move was reversed by the International Commission on Zoological Nomenclature in the late 1950s, and Entamoeba has stayed stable ever since. ...
In silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species | Semantic ScholarIn silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species | Semantic Scholar
Covalent modification of proteins by ubiquitin (Ub) and ubiquitin-like modifiers (Ubls) regulates many cellular functions in eukaryotes. These modifications are likely to be associated with pathogenesis, growth, and development of many protozoan parasites but molecular details about this pathway are unavailable for most protozoa. This study presents an analysis of the Ub pathway in three members of the Entamoeba species. Using bioinformatics tools we have identified all Ub and Ubl genes along with their corresponding activating, conjugating, and ligating enzymes (E1, E2s, and E3s) in three Entamoeba species, Entamoeba histolytica, Entamoeba dispar, and Entamoeba invadens. Phylogenetic trees were established for the identified E2s and RING finger E3s using maximum-likelihood method to infer the relationship among these proteins. In silico co-domain analysis of RING finger E3s implicates these proteins in a variety of functions. Several known and putative regulatory motifs were identified in the upstream
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Date:. May 20, 2012. Source:. University of California, San Diego Health Sciences. Summary:. An existing drug has been found to be effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.. Research by a collaborative group of scientists from UC San Diego School of Medicine, UC San Francisco and Wake Forest School of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.. Using a high-throughput screen for drugs developed by the research team, they discovered that auranofin -- a drug approved by the US Food and Drug Administration 25 years ago for rheumatoid arthritis -- is very effective in targeting an enzyme that protects amebae from oxygen attack (thus enhancing sensitivity of the amebae to reactive ...
Amoebiasis (Amoebic Dysentery) Causes, Symptoms, Diagnosis, Complications & TreatmentAmoebiasis (Amoebic Dysentery) Causes, Symptoms, Diagnosis, Complications & Treatment
Amoebiasis, also known as amoebic dysentery, is a bacterial infection caused by any of the amoebas of Entamoeba group, most commonly Entamoeba histolytica..
Go to Amebiasis.Go to Amebiasis.
Amebiasis FAQ. Amebiasis What is amebiasis? Amebiasis is an intestinal illness caused by a microscopic parasite called Entamoeba histolytica.. Who gets amebiasis? Anyone can get amebiasis, but it occurs more often in people arriving from tropical countries that have poor sanitary conditions, in individuals in institutions for the developmentally disabled, and in men who have sex with men.. How is amebiasis spread? The disease can be spread through food or water that has been contaminated with feces from an infected person. It can also be spread from person-to-person through sexual practices with fecal-oral contact. Infected people are the only sources of the parasite.. What are the symptoms of amebiasis? People exposed to this parasite may experience mild or severe symptoms or no symptoms at all. Only about 10% to 20% of people who are infected become sick, and most infected people do not become seriously ill. The symptoms of amebiasis include diarrhea, stomach pain, and stomach cramping. Amebic ...
The genome and transcriptome of the enteric parasite Entamoeba invadens , a model for encystation | Genome Biology | Full TextThe genome and transcriptome of the enteric parasite Entamoeba invadens , a model for encystation | Genome Biology | Full Text
Several eukaryotic parasites form cysts that transmit infection. The process is found in diverse organisms such as Toxoplasma, Giardia, and nematodes. In Entamoeba histolytica this process cannot be induced in vitro, making it difficult to study. In Entamoeba invadens, stage conversion can be induced, but its utility as a model system to study developmental biology has been limited by a lack of genomic resources. We carried out genome and transcriptome sequencing of E. invadens to identify molecular processes involved in stage conversion. We report the sequencing and assembly of the E. invadens genome and use whole transcriptome sequencing to characterize changes in gene expression during encystation and excystation. The E. invadens genome is larger than that of E. histolytica, apparently largely due to expansion of intergenic regions; overall gene number and the machinery for gene regulation are conserved between the species. Over half the genes are regulated during the switch between morphological
New insights into the phylogeny of Entamoeba species provided by analysis of four new small-subunit rRNA genes | Microbiology...New insights into the phylogeny of Entamoeba species provided by analysis of four new small-subunit rRNA genes | Microbiology...
Sequences of small-subunit rRNA genes have been obtained for four new isolates of Entamoeba. Phylogenetic analyses give new insights into the evolution of these organisms. A novel Entamoeba from pigs in Vietnam that produces uninucleate cysts proved to be unrelated to other uninucleated cyst-producing species. Revival of the name Entamoeba suis for this organism is proposed. Instead of being related to Entamoeba polecki, it shares a recent common ancestor with the non-encysting Entamoeba gingivalis in a lineage that is basal to the tetranucleate cyst-producing clade. This suggests that species producing cysts with four nuclei are descended from an ancestor that produced cysts with a single nucleus. An Entamoeba from a horse was isolated in culture. No cysts were observed in the original stool sample but the sequence is placed unequivocally within the clade of tetranucleate cyst-producing species with no other sequences being specifically related. Revival of the name Entamoeba equi for this organism is
ASMscience | Intestinal Protozoa: AmeASMscience | Intestinal Protozoa: Ame
Entamoeba histolytica Entamoeba dispar Entamoeba moshkovskii Entamoeba bangladeshi Entamoeba hartmanni Entamoeba coli Entamoeba polecki Entamoeba gingivalis Endolimax nana Iodamoeba bütschlii Blastocystis spp.
Amoebic dysentery | Health DiagnosisAmoebic dysentery | Health Diagnosis
Amoebic dysentery is an acute or chronic relapsing parasitic disease leading to damage to the digestive tract, but also possible organ complications. The cause is protozoan parasites Entamoeba hystolitica. It exists in several forms - as called trophosoites with forma magna and forma minuta, and cyst.. Man is infected by fecal-oral mechanism by contaminated hands, water, foodstuffs, in which the digestive tract falls cyst. From the mature one is De-couple amoebas as forma minuta. They can remain in the intestinal lumen for a long time without causing a clinic, but are a source of new cysts in the environment. In moving to forma magna however occurs inflammation of the lining of the colon under the action of enzymes secreted by the parasite to growth and even possibly passing into the bloodstream amoebas, by which the latter may be localized in various tissues with the formation of pus local collections - abscesses.. ...
KEGG PATHWAY: Amoebiasis - Mus musculus (mouse)KEGG PATHWAY: Amoebiasis - Mus musculus (mouse)
Entamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis of amoebiasis begins with parasite attachment and disruption of the intestinal mucus layer, followed by apoptosis of host epithelial cells. Intestinal tissue destruction causes severe dysentery and ulcerations in amoebic colitis. Several amoebic proteins such as lectins, cysteine proteineases, and amoebapores are associated with the invasion process. The parasite can cause extraintestinal infection like amoebic liver abscess by evading immune response ...
Entameba muris | definition of Entameba muris by Medical dictionaryEntameba muris | definition of Entameba muris by Medical dictionary
Looking for online definition of Entameba muris in the Medical Dictionary? Entameba muris explanation free. What is Entameba muris? Meaning of Entameba muris medical term. What does Entameba muris mean?
Medicines And Drugs Used In Amoebiasis - Medicine That Touches The WorldMedicine That Touches The WorldMedicines And Drugs Used In Amoebiasis - Medicine That Touches The WorldMedicine That Touches The World
Amoebiasis is a worldwide disease, particularly common in tropical countries and places where public hygiene and sanitation are poor. Amoebic infection is caused by an organism, Entamoeba histolytica (EH) which usually spreads through contaminated food and water. Since the causative organism of amoebiasis derives its nutrition from the normal bacterial flora of the large intestine, the latter is the chief site of infection. However, in some cases it may spread to other organs of the body, liver being the most susceptible to infection. Based on the site of the infection, the disease has been divided into intestinal and extra-intestinal amoebiasis.. Intestinal Amoebic Infection: During the acute phase of intestinal amoebiasis the patient may have loose motions, with or without mucus and blood, besides griping pain in the abdomen which may be severe at the time of evacuation. In chronic amoebiasis, a patient may complain of a dull pain in the lower abdomen, alternate constipation and diarrhoea, ...
amoebiasis Archives - Medicine That Touches The Worldamoebiasis Archives - Medicine That Touches The World
Amoebiasis is a worldwide disease, particularly common in tropical countries and places where public hygiene and sanitation are poor. Amoebic infection is caused by an organism, Entamoeba histolytica (EH) which usually spreads through contaminated food and water. Since the causative organism of amoebiasis derives its nutrition from the normal bacterial flora of the large intestine, the latter is the chief site of infection. However, in some cases it may spread to other organs of the body, liver being the most susceptible to infection. Based on the site of the infection, the disease has been divided into intestinal and extra-intestinal amoebiasis.. Intestinal Amoebic Infection: During the acute phase of intestinal amoebiasis the patient may have loose motions, with or without mucus and blood, besides griping pain in the abdomen which may be severe at the time of evacuation. In chronic amoebiasis, a patient may complain of a dull pain in the lower abdomen, alternate constipation and diarrhoea, ...
Infections Acute Intestinal Amebiasis Therapy Area Pipeline ReportInfections Acute Intestinal Amebiasis Therapy Area Pipeline Report
Life Science Analytics, Acute Intestinal Amebiasis Therapy Area Pipeline Report contains detailed information on the acute intestinal amebiasis drug pipeline.
THE AMEBIC COLITIS WHICH C A USED COLONIC PERFORATION (CASE REPORT) [Ulus Travma Acil Cerrahi Derg]THE AMEBIC COLITIS WHICH C A USED COLONIC PERFORATION (CASE REPORT) [Ulus Travma Acil Cerrahi Derg]
Entamoeba histolytica is a parasite that lives in colon without damaging its environment. But when it involves mucosa and submucosa, it may manifest clinical symptoms. In this report, a case of colon perforation which was a rare complication of intestinal amebiasis was presented, and intestinal amebiasis cases in the literature were reviewed in the light of current diagnosis and treatment strategies.. Keywords: COLON, AMEBIASIS, ...
Diarrhoea in a Returning Traveller - USGE - Ulster Society of GastroenterologyDiarrhoea in a Returning Traveller - USGE - Ulster Society of Gastroenterology
Amoebic colitis is an uncommon condition in the UK which usually presents with diarrhoea, with or without bleeding. Severity can range from mild diarrhoea to amoebic dysentery requiring hospitalisation. Treatments are however much different so it is important to make a correct diagnosis early in the course of the illness. The adverse effects of steroids and disease modifying agents for Crohns disease are such that making this diagnosis rather than amoebic colitis potentially carries significant harm. In addition, given the potential infectivity of carriers of Entamoeba Histolytica cysts it is of interest to diagnose and treat this early.. A 43 year old woman presented to the gastroenterology clinic with resurgent complaints of unremitting diarrhoea, without features of PR bleeding or abdominal pain. At that time she had a three year history of diagnosed Crohns disease affecting the colon. Her original presenting symptoms were of profuse diarrhoea which had been refractory to antimotility ...
Amoebic Dysentery | Grand Strand HealthAmoebic Dysentery | Grand Strand Health
Learn more about Amoebic Dysentery at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Amoebic Dysentery Treatment Options And How to Choose OneAmoebic Dysentery Treatment Options And How to Choose One
Medication, ORS solutions, and probiotics are some of the options available for amoebic dysentery treatment. Consult a doctor soon, as the disease can turn fatal.
Medical Chemical Corporation: Para-siteMedical Chemical Corporation: Para-site
1These two fixatives use the mercuric chloride base in the Schaudinns fixative; this formulation is still considered to be the "gold standard" against which all other fixatives are evaluated (organism morphology after permanent staining).. 2This modification uses a copper sulfate base rather than mercuric chloride; morphology of stained organisms not as good as with Hg or Zn.. 3This modification (proprietary formula) uses a zinc base rather than mercuric chloride and works well with both trichrome and iron-hematoxylin.. 4This fixative uses a combination of ingredients, but is prepared from a proprietary formula (contains PVA).. 5This modification uses a combination of ingredients (including zinc), but is prepared from a proprietary formula. The aim is to provide a "Universal Fixative" that can be used for the fecal concentration, permanent stained smear, and available immunoassays for Giardia lamblia, Cryptosporidium spp., and Entamoeba histolytica (or the Entamoeba histolytica/E. dispar ...
RCSB PDB - 4UP7: Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylateRCSB PDB - 4UP7: Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylate
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
A06.1 CHRONIC INTESTINAL AMEBIASISA06.1 CHRONIC INTESTINAL AMEBIASIS
ICD-10 A06.1 is chronic intestinal amebiasis (A061). This code is grouped under diagnosis codes for certain infectious and parasitic diseases.
Endamoeba | Define Endamoeba at Dictionary.comEndamoeba | Define Endamoeba at Dictionary.com
Endamoeba definition, any protozoan of the genus Endamoeba, members of which are parasitic in the digestive tracts of various invertebrates, including cockroaches and termites. See more.
DMOZ - Health: Conditions and Diseases: Infectious Diseases: Parasitic: AmebiasisDMOZ - Health: Conditions and Diseases: Infectious Diseases: Parasitic: Amebiasis
Amebiasis is defined as disease caused by amoebas, one-celled parasites. They cause Amebic Dysentery and a variety of other diseases.
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AmebiasisAmebiasis
Positive serological test(s) for E. histolytica with clinical evidence of invasive amebiasis. (Invasive amebiasis presents as an acute abscess in the liver, lung, brain or other organs or rarely as a granulomatous lesion in the intestine.) OR ...
Domain assignment for jCVI|EIN 138460 from Entamoeba invadens 1.2Domain assignment for jCVI|EIN 138460 from Entamoeba invadens 1.2
Domain architecture and assignment details (superfamily, family, region, evalue) for jCVI|EIN_138460 from Entamoeba invadens 1.2. Plus protein sequence and external database links.
Domain assignment for jCVI|EIN 262510 from Entamoeba invadens 1.2Domain assignment for jCVI|EIN 262510 from Entamoeba invadens 1.2
Domain architecture and assignment details (superfamily, family, region, evalue) for jCVI|EIN_262510 from Entamoeba invadens 1.2. Plus protein sequence and external database links.
peptidyl trna Protocols and Video...'peptidyl trna' Protocols and Video...
Video articles in JoVE about peptidyl trna include Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses, Phloem Sap Sampling from Brassica Napus for 3D-PAGE of Protein and Ribonucleoprotein Complexes, Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve, Chromatographic Purification of Highly Active Yeast Ribosomes, Isolation of Ribosome Bound Nascent Polypeptides in vitro to Identify Translational Pause Sites Along mRNA, Quantitative Immunofluorescence to Measure Global Localized Translation, Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides, Quantification of the Abundance and Charging Levels of Transfer RNAs in Escherichia coli, Protein-tRNA Agarose Gel Retardation Assays for the Analysis of the N6-threonylcarbamoyladenosine TcdA Function, In vitro tRNA Methylation Assay with the Entamoeba histolytica DNA and tRNA Methyltransferase Dnmt2 (Ehmeth) Enzyme, Residue-specific
Amebiasis: Home CareAmebiasis: Home Care
Another name for Amebiasis is Extraintestinal Amebiasis. Home care for extraintestinal amebiasis includes: * Drink plenty of fluids. * Avoid milk and ...
schoenerblog: NursingCrib.com Nursing Care Plan Amoebiasis by nursingcribschoenerblog: NursingCrib.com Nursing Care Plan Amoebiasis by nursingcrib
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Amoebic Hepatic Abscess - Medical Dictionary online-medical-dictionary.orgAmoebic Hepatic Abscess - Medical Dictionary online-medical-dictionary.org
Single or multiple areas of PUS due to Infection by any ameboid protozoa (Amebiasis). A common form is caused by the ingestion of Entamoeba histolytica ...
아메바성 이질 치료하는 법: 13 단계 (이미지 포함) - wikiHow아메바성 이질 치료하는 법: 13 단계 (이미지 포함) - wikiHow
아메바성 이질 치료하는 법. 아메바성 이질(Amebiasis)은 이질아메바(Entamoeba histolytica)라고 불리는 기생충에 의해 발생하는 감염증이다.http://www.nlm.nih.gov/medlineplus/ency/article/000298.htm 이 기생충은 장내 또는 장외 질환의 원인이 되는데 장내 질환의 경우 발열, 오한, 혈변 또는 점액성 설사, 복부 불편감, 설사와 변비가 번갈아가며 나타나는 증상...
PseudopodiaPseudopodia
AmoebaAmoeba
DiarrheaDiarrhea
ProtozoaProtozoa
TrypanothioneTrypanothione
BlastocystosisBlastocystosis
SerotoninSerotonin
HistolysainHistolysain
Amoebic brain abscessAmoebic brain abscess
Pyruvate oxidase (CoA-acetylating)Pyruvate oxidase (CoA-acetylating)
OrganelleOrganelle
Substance PSubstance P
William A. PetriWilliam A. Petri
G proteinG protein
Acetate kinase (diphosphate)Acetate kinase (diphosphate)
Unicellular organismUnicellular organism
List of sequenced protist genomesList of sequenced protist genomes
Refugee healthRefugee health
AmoebiasisAmoebiasis
Phosphoglycerate kinase (GTP)Phosphoglycerate kinase (GTP)
DigestionDigestion
NitazoxanideNitazoxanide
Cutaneous amoebiasisCutaneous amoebiasis
Travelers diarrheaTraveler's diarrhea
Lung abscessLung abscess
HouseflyHousefly
Acetate-CoA ligase (ADP-forming)Acetate-CoA ligase (ADP-forming)
Saliva testingSaliva testing
Toxic megacolonToxic megacolon
Zanvil A. CohnZanvil A. Cohn
Substance PSubstance P
Mikroorganismid - VikipeediaMikroorganismid - Vikipeedia
Category:Protista - Simple English Wikipedia, the free encyclopediaCategory:Protista - Simple English Wikipedia, the free encyclopedia
Hepatit - VikipediHepatit - Vikipedi
Innate immune systemInnate immune system
Srinivasa RamanujanSrinivasa Ramanujan
Doris MackinnonDoris Mackinnon
Eukaryoty - WikipédiaEukaryoty - Wikipédia
Usuario:AVBOT/Reversiones humanas/2009/10/27, la enciclopedia libreUsuario:AVBOT/Reversiones humanas/2009/10/27, la enciclopedia libre
Kategoria:Amoebozoa, entziklopedia askea.Kategoria:Amoebozoa, entziklopedia askea.
InfectionInfection
ProtozoaProtozoa
Amoebic liver abscessAmoebic liver abscess
Gastroenteraytis, ang malayang ensiklopedyaGastroenteraytis, ang malayang ensiklopedya
Mitozom - WikipedieMitozom - Wikipedie
CorticosteroidCorticosteroid
G proteinG protein
Basal - Simple English Wikipedia, the free encyclopediaBasal - Simple English Wikipedia, the free encyclopedia
Amoeba, ang malayang ensiklopedyaAmoeba, ang malayang ensiklopedya
DigestionDigestion
Mouth ulcerMouth ulcer
நுண்ணுயிர் காப்புக்கூடு - தமிழ் விக்கிப்பீடியாநுண்ணுயிர் காப்புக்கூடு - தமிழ் விக்கிப்பீடியா
Gastroenteritis, entziklopedia askea.Gastroenteritis, entziklopedia askea.
Mikroorganismid - Vikipeedia, vaba entsüklopeediaMikroorganismid - Vikipeedia, vaba entsüklopeedia
Generally recognized as safeGenerally recognized as safe
Food safetyFood safety
Fagozitosi, entziklopedia askea.Fagozitosi, entziklopedia askea.
Brain abscessBrain abscess
AnatomyOrganismsDiseasesChemicals and DrugsPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth CareGeographicals
Entamoeba histolyticaEntamoebaEntamoebiasisDysentery, AmebicLiver Abscess, AmebicTrophozoitesAmebicidesAmebiasisProtozoan ProteinsIntestinal Diseases, ParasiticProtozoan InfectionsDNA, ProtozoanFecesGiardia lambliaAntigens, ProtozoanGenome, ProtozoanCysteine ProteasesLectinsGenes, ProtozoanAcetylgalactosamineParasitologyAntibodies, ProtozoanDientamoebaBlastocystis hominisAntiprotozoal AgentsGerbillinaeParasitesMolecular Sequence DataEndolimaxMetronidazoleGiardiasisGiardiaGalactoseProtozoan VaccinesGalectinsLiver AbscessAmino Acid SequenceIodoquinolAdhesivenessBangladeshSerine O-AcetyltransferaseHost-Parasite InteractionsPyruvate SynthaseTrichomonasSuppurationDysenteryMaterial Safety Data SheetsAccess to InformationGastroenterologyBibliometricsPeriodicals as TopicJournal Impact Factor
Category:Entamoeba histolytica - Wikimedia CommonsCategory:Entamoeba histolytica - Wikimedia Commons
Entamoeba histolyticaEntamoeba histolytica
Entamoeba histolytica Schaudinn ATCC ® 30015™Entamoeba histolytica Schaudinn ATCC ® 30015™
Entamoeba histolytica: Gene Expression Analysis of Cells Invading TissuesEntamoeba histolytica: Gene Expression Analysis of Cells Invading Tissues
LINEs and SINE-like elements of the protist Entamoeba histolytica. - PubMed - NCBILINEs and SINE-like elements of the protist Entamoeba histolytica. - PubMed - NCBI
Medline ® Abstract for Reference 42 of Intestinal Entamoeba histolytica amebiasisMedline ® Abstract for Reference 42 of 'Intestinal Entamoeba histolytica amebiasis'
KEGG PATHWAY: Nucleotide excision repair - Entamoeba histolyticaKEGG PATHWAY: Nucleotide excision repair - Entamoeba histolytica
EHI 093910 - Histidine triad nucleotide-binding protein - Entamoeba histolytica - EHI 093910 gene & proteinEHI 093910 - Histidine triad nucleotide-binding protein - Entamoeba histolytica - EHI 093910 gene & protein
Entamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo LibraryEntamoeba histolytica parasites - Stock Video Clip K003/8943 - Science Photo Library
Entamoeba histolytica (sect) ih | Boreal ScienceEntamoeba histolytica (sect) ih | Boreal Science
Exploring The Short Interspersed Nuclear Elements For Genotyping Entamoeba Histolytica | 21192Exploring The Short Interspersed Nuclear Elements For Genotyping Entamoeba Histolytica | 21192
Molecules | Free Full-Text | Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican...Molecules | Free Full-Text | Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican...
Characterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal InfectionCharacterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal Infection
Entamoeba histolytica Cysteine Proteinases Disrupt the Polymeric Structure of Colonic Mucin and Alter Its Protective Function |...Entamoeba histolytica Cysteine Proteinases Disrupt the Polymeric Structure of Colonic Mucin and Alter Its Protective Function |...
Entamoeba histolytica - WikipediaEntamoeba histolytica - Wikipedia
Entamoeba histolytica | protozoan | Britannica.comEntamoeba histolytica | protozoan | Britannica.com
Entamoeba histolyticaEntamoeba histolytica
Amebiasis: Infection and Disease by Entamoeba Histolytica - 1st EditioAmebiasis: Infection and Disease by Entamoeba Histolytica - 1st Editio
Tissue destruction and invasion by Entamoeba histolyticaTissue destruction and invasion by Entamoeba histolytica
Entamoeba histolytica HM-1:IMSS gcontig 1104750507432, whole genome sh - Nucleotide - NCBIEntamoeba histolytica HM-1:IMSS gcontig 1104750507432, whole genome sh - Nucleotide - NCBI
Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine DevelopmentEntamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development
Thiol proteinase expression and pathogenicity of Entamoeba histolyticaThiol proteinase expression and pathogenicity of Entamoeba histolytica
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica | PNASPrimary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica | PNAS
Possible Function of Entamoeba histolytica in Creation Model | Answers in Genesis Possible Function of Entamoeba histolytica in Creation Model | Answers in Genesis
A Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine GlycolA Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine Glycol
ENL-1 - Enolase 1 - Entamoeba histolytica - ENL-1 gene & proteinENL-1 - Enolase 1 - Entamoeba histolytica - ENL-1 gene & protein
What Is Amebiasis (Entamoeba histolytica Infection)? Treatment & SymptomsWhat Is Amebiasis (Entamoeba histolytica Infection)? Treatment & Symptoms
Entamoeba histolytica - wikidocEntamoeba histolytica - wikidoc
Cytopathogenicity of Entamoeba histolytica: hemolytic activity of trophozoite homogenates.Cytopathogenicity of Entamoeba histolytica: hemolytic activity of trophozoite homogenates.
Symptoms of Entamoeba HistolyticaSymptoms of Entamoeba Histolytica
cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. | PNAScDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica. | PNAS
RCSB PDB - 3M4P: Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylateRCSB PDB - 3M4P: Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
The Biology of Entamoeba histolytica | The American Journal of Tropical Medicine and HygieneThe Biology of Entamoeba histolytica | The American Journal of Tropical Medicine and Hygiene
RCSB PDB - 4UP7: Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylateRCSB PDB - 4UP7: Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylate
Migration of Entamoeba Histolytica under Agarose* | The American Journal of Tropical Medicine and HygieneMigration of Entamoeba Histolytica under Agarose* | The American Journal of Tropical Medicine and Hygiene
AnatomyOrganismsDiseasesChemicals and DrugsPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth CareGeographicals
Entamoeba histolyticaEntamoebaEntamoebiasisDysentery, AmebicLiver Abscess, AmebicTrophozoitesAmebicidesAmebiasisProtozoan ProteinsIntestinal Diseases, ParasiticProtozoan InfectionsDNA, ProtozoanFecesGiardia lambliaAntigens, ProtozoanGenome, ProtozoanCysteine ProteasesLectinsGenes, ProtozoanAcetylgalactosamineParasitologyAntibodies, ProtozoanDientamoebaBlastocystis hominisAntiprotozoal AgentsGerbillinaeParasitesMolecular Sequence DataEndolimaxMetronidazoleGiardiasisGiardiaGalactoseProtozoan VaccinesGalectinsLiver AbscessAmino Acid SequenceIodoquinolAdhesivenessBangladeshSerine O-AcetyltransferaseHost-Parasite InteractionsPyruvate SynthaseTrichomonasSuppurationDysenteryMaterial Safety Data SheetsAccess to InformationGastroenterologyBibliometricsPeriodicals as TopicJournal Impact Factor
TrophozoitesAmebiasisAmoebiasisCryptosporidiumInfectionProtozoan parasite Entamoeba histolyticaParasitesIsolatesSpeciesVirulencePathogenesisParasiticStrainsProtistInfectionsDetectionCharacterizationAntibodiesSpecimensHomologousPathogensAmoebiasisIntestinalAntibodyPathogenicProtozoaParasitic protozoanAmebic dysenteryCysteineSerumLiver abscessCaused by the protozoanGenusInvasiveQuestions about entamoeba histolyticaELISANonpathogenicAntigensEntericCausativeCystClinicalMicroscopyTrophozoiteLarge intestineAntigen entamoebaParasite entamoebaLectinProteinsAsymptomaticDiarrhea
Trophozoites2
Amebiasis7
Amoebiasis2
Cryptosporidium1
Infection2
Protozoan parasite Entamoeba histolytica1
Parasites2
Isolates4
  • Due to their mobile nature, some EhSINE copies may occupy different genomic locations among isolates of E. histolytica possibly affecting adjacent gene expression. (omicsonline.org)
  • We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model. (elsevier.com)
  • To investigate the possible existence of invasive and noninvasive strains as one factor, the ability to differentiate individual isolates of E. histolytica is necessary. (lshtm.ac.uk)
  • Use of multiple loci collectively allowed differentiation of a majority of the 13 isolates studied, and we believe that these loci have the potential to be used as polymorphic molecular markers for investigating the epidemiology of E. histolytica and the potential existence of genetically distinct invasive and noninvasive strains. (lshtm.ac.uk)
Species1
Virulence1
Pathogenesis2
Parasitic1
  • June 14: According to the World Health Organization (WHO), Entamoeba histolytica is the third-leading cause of morbidity and mortality due to parasitic disease in humans. (indiaties.in)
Strains1
Protist1
Infections1
Detection3
Characterization1
Antibodies1
Specimens1
  • A total of 94% of patients treated with nitazoxanide were free of Entamoeba histolytica in two post-treatment stool specimens compared with only 43% of patients receiving placebo. (oncologynurseadvisor.com)
Homologous1
Pathogens1
  • The adherent mucous gel layer lining the colonic epithelium is the first line of host defense against invasive pathogens, such as Entamoeba histolytica . (asm.org)
Amoebiasis19
Intestinal10
Antibody1
Pathogenic9
Protozoa6
Parasitic protozoan2
Amebic dysentery4
Cysteine8
  • The release of a histolytic cysteine proteinase from E. histolytica correlates with the pathogenicity of both axenic strains and recent clinical isolates as determined by clinical history of invasive disease, zymodeme analysis, and cytopathic effect. (jci.org)
  • It inhibits many of the key enzymes that are involved in the metabolism and virulence of the parasite Entamoeba histolytica through S-nitrosylation of essential cysteine residues. (asm.org)
  • An important virulence factor, a 27-kDa cysteine protease, was also enriched in early and late endosomes of E. histolytica . (unl.edu)
  • Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. (asm.org)
  • E. histolytica secreted products were examined for mucinase activity utilizing mucin metabolically labeled with [ 35 S]cysteine as a substrate. (asm.org)
  • These results are the first to show that E. histolytica cysteine proteinases alter the protective function of the mucous barrier by disrupting the structure of the MUC2 polymer. (asm.org)
  • A number of studies have shown that peptidases and in particular cysteine peptidases constitute major pathogenicity factors in Entamoeba histolytica . (biomedcentral.com)
  • Cysteine peptidases are considered to play a major role for the pathogenicity of E. histolytica as suggested by a large number of in vitro and in vivo studies [ 1 - 9 ]. (biomedcentral.com)
Serum5
  • The library was screened with rabbit polyclonal anti-E. histolytica serum. (pnas.org)
  • We demonstrate that E. histolytica acquires and displays human cell membrane proteins through trogocytosis and that this leads to protection from lysis by human serum. (asm.org)
  • Here, we demonstrate for the first time that E. histolytica acquires and displays human cell membrane proteins by taking "bites" of human cell material in a process named trogocytosis ("trogo-" means "nibble"), and that this allows amoebae to survive in human serum. (asm.org)
  • Western blots using excretory-secretory antigen (ESA) collected from axenically grown Entamoeba histolytica were probed with the above serum samples. (asm.org)
  • The RIDASCREEN® Entamoeba histolytica IgG test is an enzyme immunoassay for the qualitative determination of IgG antibodies against Entamoeba histolytica in human serum. (r-biopharm.com)
Liver abscess4
Caused by the protozoan1
Genus1
Invasive5
  • To interrupt transmission of the parasite and to avoid progression of infected individuals to invasive disease, treatment of E. histolytica carriers has been recommended ( 36 ). (asm.org)
  • W hile an estimated 90% of E. histolytica infections are asymptomatic, prospective studies of asymptomatic carriers indicate a risk of invasive disease of 5/56 (9%) over the course of 6-12 months ( 26 ). (antimicrobe.org)
  • Accordingly, the risk of developing invasive disease, as well as decreased transmission, are rationales for treating asymptomatic carriers of E. histolytica , however WHO recommends against treatment of asymptomatic patients when only a morphologic diagnosis by stool examination is available (i.e. (antimicrobe.org)
  • The adherent mucous gel layer lining the colonic epithelium is the first line of host defense against invasive pathogens, such as Entamoeba histolytica . (asm.org)
  • E.histolytica always elicits a serological response whether it is invasive or whether the person is asymptomatic -- only 10 precent do develop serious disease. (parasite.org.au)
Questions about entamoeba histolytica1
  • Please feel free to email us at the email address below with any insights, coments, or questions about entamoeba histolytica. (entamoebahistolytica.org)
ELISA3
Nonpathogenic1
Antigens1
  • A gamma gt11 cDNA library was constructed from poly(U)-Sepharose-selected Entamoeba histolytica trophozoite RNA in order to clone and identify surface antigens. (pnas.org)
Enteric1
Causative1
Cyst1
Clinical2
Microscopy3
Trophozoite3
Large intestine1
Antigen entamoeba1
Parasite entamoeba4
Lectin4
  • E. histolytica has a lectin that binds to galactose and N-acetylgalactosamine sugars on the surface of the epithelial cells, The lectin normally is used to bind bacteria for ingestion. (wikipedia.org)
  • The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa surface lectin of the amoebae. (pnas.org)
  • From the matrix-assisted laser desorption ionization-two-stage time of flight (MALDI-TOF/TOF) analysis, the proteins were identified as heavy subunits of E. histolytica lectin and E. histolytica pyruvate phosphate dikinase, respectively. (asm.org)
  • Use of the E. histolytica lectin for diagnosis of ALA has been well reported by researchers and is being used in commercialized kits. (asm.org)
Proteins3
  • To begin to identify the role of Rab GTPases in E. histolytica , an oligonucleotide approach was employed to screen an E. histolytica cDNA library for genes encoding Rab-like proteins. (unl.edu)
  • Phylogenetic analysis and alignment of EhRab11 with other Rab proteins demonstrated that EhRab11 shared significant homology at the amino acid level with Rab 11-like proteins from a number of other eukaryotes, suggesting that EhRab11 is a Rab11 homolog for E. histolytica . (unl.edu)
  • We have assigned putative function to 3,788 proteins (46% of the predicted proteome) based on the annotation of predicted gene families, and have identified 58 protein families of five or more members that share no homology with known proteins and thus could be entamoeba specific. (pubmedcentralcanada.ca)
Asymptomatic1
Diarrhea1
  • Children homozygous for the R223 allele were 4 times more likely to have E. histolytica diarrhea than those homozygous for the wild-type Q223 allele. (asm.org)
Entamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase Family
Entamoeba histolytica Phagocytosis of Human Erythrocytes Involves PATMK, a Member of the Transmembrane Kinase Family (journals.plos.org)
Category:Entamoeba histolytica - Wikimedia Commons
Category:Entamoeba histolytica - Wikimedia Commons (commons.wikimedia.org)
Frank Sherwin | Answers in Genesis | Answers in Genesis
Frank Sherwin | Answers in Genesis | Answers in Genesis (answersingenesis.org)
A Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine Glycol
A Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine Glycol (journals.plos.org)
Entamoeba histolytica | protozoan | Britannica.com
Entamoeba histolytica | protozoan | Britannica.com (britannica.com)
Amebiasis | Summary | NNDSS
Amebiasis | Summary | NNDSS (wwwn.cdc.gov)
Oregon Health Authority : Parasite Images from the Oregon State Public Health Laboratory : Parasite Images Library : State of...
Oregon Health Authority : Parasite Images from the Oregon State Public Health Laboratory : Parasite Images Library : State of... (oregon.gov)
Amebiasis: Infection and Disease by Entamoeba Histolytica - 1st Editio
Amebiasis: Infection and Disease by Entamoeba Histolytica - 1st Editio (routledge.com)
Erythrophagocytosis in Entamoeba histolytica and Entamoeba dispar: A Comparative Study
Erythrophagocytosis in Entamoeba histolytica and Entamoeba dispar: A Comparative Study (hindawi.com)
The top ten parasites that could be lurking in your food
The top ten parasites that could be lurking in your food (theconversation.com)
JCI - Volume 91, Issue 4
JCI - Volume 91, Issue 4 (jci.org)
JCI - Cloning of a virulence factor of Entamoeba histolytica. Pathogenic strains possess a unique cysteine proteinase gene.
JCI - Cloning of a virulence factor of Entamoeba histolytica. Pathogenic strains possess a unique cysteine proteinase gene. (jci.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
ASTMH - Zaiman Slide Library
ASTMH - Zaiman Slide Library (astmh.org)
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica | PNAS
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica | PNAS (pnas.org)
Traveler's diarrhea - Wikipedia
Traveler's diarrhea - Wikipedia (en.wikipedia.org)
CDC - DPDx - Diagnostic Procedures - Stool Specimens
CDC - DPDx - Diagnostic Procedures - Stool Specimens (cdc.gov)
CDC - DPDx - Amebiasis
CDC - DPDx - Amebiasis (cdc.gov)
Lung abscess - Wikipedia
Lung abscess - Wikipedia (en.wikipedia.org)
Table of Contents - August 19, 1983, 221 (4612) | Science
Table of Contents - August 19, 1983, 221 (4612) | Science (science.sciencemag.org)
RCSB PDB - 3M4P: Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
RCSB PDB - 3M4P: Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate (rcsb.org)
CDC - Migrant Serum Bank - Immigrant and Refugee Health
CDC - Migrant Serum Bank - Immigrant and Refugee Health (cdc.gov)
Coloured SEM of Entamoeba histolytica in colon - Stock Image - M140/0249 - Science Photo Library
Coloured SEM of Entamoeba histolytica in colon - Stock Image - M140/0249 - Science Photo Library (sciencephoto.com)
Clinical Care
Clinical Care (aap.org)
Surgical Pathology of the Gastrointestinal System: Bacterial, Fungal, Viral, and Parasitic Infections | SpringerLink
Surgical Pathology of the Gastrointestinal System: Bacterial, Fungal, Viral, and Parasitic Infections | SpringerLink (link.springer.com)
1. Wastewater characteristics and effluent quality parameters
1. Wastewater characteristics and effluent quality parameters (fao.org)
PLOS Neglected Tropical Diseases: Publishing science, accelerating research
PLOS Neglected Tropical Diseases: Publishing science, accelerating research (journals.plos.org)