Pericardium
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Endocardial Cushions
Heart Valves
Heart Ventricles
Heart Conduction System
Dogs
Myocardium
Endocardial Fibroelastosis
A condition characterized by the thickening of ENDOCARDIUM due to proliferation of fibrous and elastic tissue, usually in the left ventricle leading to impaired cardiac function (CARDIOMYOPATHY, RESTRICTIVE). It is most commonly seen in young children and rarely in adults. It is often associated with congenital heart anomalies (HEART DEFECTS CONGENITAL;) INFECTION; or gene mutation. Defects in the tafazzin protein, encoded by TAZ gene, result in a form of autosomal dominant familial endocardial fibroelastosis.
Epicardial Mapping
Electrophysiologic Techniques, Cardiac
Action Potentials
Ventricular Fibrillation
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Purkinje Fibers
Endocardial Cushion Defects
A spectrum of septal defects involving the ATRIAL SEPTUM; VENTRICULAR SEPTUM; and the atrioventricular valves (TRICUSPID VALVE; BICUSPID VALVE). These defects are due to incomplete growth and fusion of the ENDOCARDIAL CUSHIONS which are important in the formation of two atrioventricular canals, site of future atrioventricular valves.
Cardiac Pacing, Artificial
Tachycardia, Ventricular
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
Body Surface Potential Mapping
Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)
Quail
Heart Septum
Models, Cardiovascular
Mesoderm
Catheter Ablation
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
Gene Expression Regulation, Developmental
Morphogenesis
Myocytes, Cardiac
Papillary Muscles
Flecainide
Chick Embryo
Endomyocardial Fibrosis
A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).
Electrophysiology
Receptor, TIE-2
Zebrafish
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
4-Aminopyridine
LIM-Homeodomain Proteins
Fetal Heart
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Ventricular Function, Left
Arrhythmias, Cardiac
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Cardiomyopathy, Restrictive
A form of CARDIAC MUSCLE disease in which the ventricular walls are excessively rigid, impeding ventricular filling. It is marked by reduced diastolic volume of either or both ventricles but normal or nearly normal systolic function. It may be idiopathic or associated with other diseases (ENDOMYOCARDIAL FIBROSIS or AMYLOIDOSIS) causing interstitial fibrosis.
Cardiomyopathy, Dilated
Arrhythmogenic Right Ventricular Dysplasia
Effect of warfarin on the induction and course of experimental endocarditis. (1/971)
The effect of warfarin treatment on an experimental endocarditis was studied in rabbits. Warfarin had no effect on the induction of a Streptococcus sanguis infection in catheter-induced endocardial vegetations, and the course of this infection was also unaltered. However, warfarin treatment resulted in rapidly progressive bacteremia, probably due to impaired circulation in clearing organs such as the lungs, liver, and spleen. Warfarin also reduced the survival time of the infected rabbits, in which pulmonary edema and extensive lung hemorrhages may have been a contributory factor. (+info)Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis. (2/971)
BACKGROUND: Previous studies dealing with the detection of enteroviral RNA in human endomyocardial biopsies have not differentiated between latent persistence of the enteroviral genome and active viral replication. Enteroviruses that are considered important factors for the development of myocarditis have a single-strand RNA genome of positive polarity that is transcribed by a virus-encoded RNA polymerase into a minus-strand mRNA during active viral replication. The synthesis of multiple copies of minus-strand enteroviral RNA therefore occurs only at sites of active viral replication but not in tissues with mere persistence of the viral genome. METHODS AND RESULTS: We investigated enteroviral RNA replication versus enteroviral RNA persistence in endomyocardial biopsies of 45 patients with left ventricular dysfunction and clinically suspected myocarditis. Using reverse-transcriptase polymerase chain reaction in conjunction with Southern blot hybridization, we established a highly sensitive assay to specifically detect plus-strand versus minus-strand enteroviral RNA in the biopsies. Plus-strand enteroviral RNA was detected in endomyocardial biopsies of 18 (40%) of 45 patients, whereas minus-strand RNA as an indication of active enteroviral RNA replication was detected in only 10 (56%) of these 18 plus-strand-positive patients. Enteroviral RNA was not found in biopsies of the control group (n=26). CONCLUSIONS: These data demonstrate that a significant fraction of patients with left ventricular dysfunction and clinically suspected myocarditis had active enteroviral RNA replication in their myocardium (22%). Differentiation between patients with active viral replication and latent viral persistence should be particularly important in future studies evaluating different therapeutic strategies. In addition, molecular genetic detection of enteroviral genome and differentiation between replicating versus persistent viruses is possible in a single endomyocardial biopsy. (+info)Regional electrophysiological effects of hypokalaemia, hypomagnesaemia and hyponatraemia in isolated rabbit hearts in normal and ischaemic conditions. (3/971)
OBJECTIVE: The aims of this study were to establish an isolated working heart model for electrophysiological recordings from the epicardium and endocardium and to examine regional effects of changes in ion concentrations in normal and ischaemic conditions. METHODS: Monophasic action potential duration (MAPD90), effective refractory period (ERP) and conduction delay were measured simultaneously in the epicardium and endocardium of rabbit hearts paced at 3.3 Hz, subjected to 30 min of regional ischaemia and 15 min of reperfusion. The hearts were exposed before and throughout ischaemia and reperfusion to hypokalaemia (K+ = 2 mM), hypomagnesaemia (Mg2+ = 0.5 mM) or hyponatraemia (Na+ = 110 mM). RESULTS: In the control hearts, no regional electrophysiological differences were seen before ischaemia, but ischaemia-induced MAPD90 shortening and postrepolarisation refractoriness were greater in the epicardium than in the endocardium and conduction delay increased only in the epicardium. Hypokalaemia shortened ERP in the epicardium (but not endocardium) and increased conduction delay in all areas before ischaemia, but it had no effects during ischaemia. During reperfusion hypokalaemia increased the incidence of recurrent tachyarrhythmias. Hypomagnesaemia had no effect before ischaemia, increased epicardial (but not endocardial) MAPD90 shortening during ischaemia, although it had no pro-arrhythmic action. Hyponatraemia increased conduction delay in all areas before ischaemia and produced asystole or severe bradycardia in all hearts. During ischaemia, hyponatraemia decreased ERP shortening and inducibility of arrhythmias in the epicardium (but not endocardium). CONCLUSIONS: We conclude that the more pronounced effect of ischaemia upon the epicardium than the endocardium can be explained by the contact of the endocardium with intracavitary perfusate. We also conclude that changes in ion concentrations may have differential regional electrical effects in normal or ischaemic conditions. (+info)Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart. (4/971)
Transforming growth factor-beta (TGF-beta) signaling is mediated by a complex of type I (TBRI) and type II (TBRII) receptors. The type III receptor (TBRIII) lacks a recognizable signaling domain and has no clearly defined role in TGF-beta signaling. Cardiac endothelial cells that undergo epithelial-mesenchymal transformation express TBRIII, and here TBRIII-specific antisera were found to inhibit mesenchyme formation and migration in atrioventricular cushion explants. Misexpression of TBRIII in nontransforming ventricular endothelial cells conferred transformation in response to TGF-beta2. These results support a model where TBRIII localizes transformation in the heart and plays an essential, nonredundant role in TGF-beta signaling. (+info)Bulbus arteriosus of the antarctic teleosts. I. The white-blooded Chionodraco hamatus. (5/971)
The bulbus arteriosus of teleost fish is a thick-walled chamber that extends between the single ventricle and the ventral aorta. The functional importance of the bulbus resides in the fact that it maintains a steady blood flow into the gill system through heart contraction. Despite of this, a thorough study of the structure of the bulbus in teleost fish is still lacking. We have undertaken a morphologic study of the bulbus arteriosus in the stenothermal teleosts of the Antarctic sea. The structural organization of the bulbus arteriosus of the icefish Chionodraco hamatus has been studied here by conventional light, scanning, and transmission electron microscopy. The inner surface of the bulbus shows a festooned appearance due to the presence of longitudinal, unbranched ridges that extend between the ventricle and the arterial trunk. The wall of the bulbus is divided into endocardial, subendocardial, middle, and external layers. Endocardial cells show a large number of moderately-dense bodies. The endocardium invaginates into the subendocardium forming solid epithelial cords that contain numerous secretory vacuoles. Cells in the subendocardium group into small domains, have some of the morphological characteristics of smooth muscle cells, and appear enmeshed in a three-dimensional network of matrix filaments. Cells in the middle layer are typical smooth muscle cells. They appear arranged into layers and are surrounded by a filamentous meshwork that excludes collagen fibers. Orientation of this meshwork occurs in the vicinity of the smooth muscle cells. Elastin fibers are never observed. The external layer is formed by wavy collagen bundles and fibroblast-like cells. This layer lacks blood vessels and nerve fibers. The endocardium and the endocardium-derived cords are secretory epithelia that may be involved in the formation ofmucins or glycosaminoglycans. These mucins may have a protecting effect on the endocardium. The subendocardium and the middle layer appear to be formed by the same cell type, smooth muscle, with a gradient of differentiation from the secretory (subendocardium) to the contractile (middle layer) phenotype. Despite the absence of elastin fibers, the filamentous matrix could maintain the elastic properties of the bulbus wall. Smooth muscle cells appear to be actively involved in bulbus wall dynamics. The restriction of collagen to the external layer suggests that it may control wall dilatation and bulbus compliance. When comparison was possible, structural differences between C. hamatus and temperate teleosts seemed to be not species-related, but of phenotypic adaptative significance. This is remarkable since Antarctic fishes have lived isolated in freezing waters for the last two million years. (+info)Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. (6/971)
Fas is a transmembranous glycoprotein that mediates apoptosis. To elucidate the roles of Fas and of myocyte apoptosis in patients with dilated cardiomyopathy (DCM), the expression of Fas and the fragmentation of DNA were compared in endomyocardial biopsy specimens obtained from patients with DCM. Endomyocardial biopsy was performed on 19 subjects (16 with DCM and 3 control subjects) who also underwent cardiac catheterization and echocardiography. Fas and bcl-2 expression were assayed immunohistochemically, and in situ TdT staining was performed to estimate the number of apoptotic cells. Samples from the DCM patients stained more intensely with anti-Fas antibody than those from control patients (p<0.05). The percentage of in situ TdT-positive cells was significantly higher in the DCM group than in the control group (p<0.05). A correlation between Fas expression and in situ TdT staining was observed in 67% of myocytes in the DCM group. Moreover, the percentage of in situ TdT staining was significantly higher in subjects with severely impaired left ventricular systolic function than in those whose systolic function was mild to moderately impaired, or who had normal systolic function (p<0.05). The samples showed little expression of bcl-2. These results suggest that Fas expression and apoptosis may be involved in the progression of cardiac dysfunction in DCM. (+info)Tracheal aspirate as a substrate for polymerase chain reaction detection of viral genome in childhood pneumonia and myocarditis. (7/971)
BACKGROUND: Infectious respiratory disorders are important causes of childhood morbidity and mortality. Viral causes are common and may lead to rapid deterioration, requiring mechanical ventilation; myocardial dysfunction may accompany respiratory decompensation. The etiologic viral diagnosis may be difficult with classic methods. The purpose of this study was to evaluate polymerase chain reaction (PCR) as a diagnostic method for identification of causative agents. METHODS AND RESULTS: PCR was used to amplify sequences of viruses known to cause childhood viral pneumonia and myocarditis. Oligonucleotide primers were designed to amplify specific sequences of DNA virus (adenovirus, cytomegalovirus, herpes simplex virus, and Epstein-Barr virus) and RNA virus (enterovirus, respiratory syncytial virus, influenza A, and influenza B) genomes. Tracheal aspirate samples were obtained from 32 intubated patients and nucleic acid extracted before PCR. PCR results were compared with results of culture, serology, and antigen detection methods when available. In cases of myocarditis (n=7), endomyocardial biopsy samples were analyzed by PCR and compared with tracheal aspirate studies. PCR amplification of viral genome occurred in 18 of 32 samples (56%), with 3 samples PCR positive for 2 viral genomes. Amplified viral sequences included RSV (n=3), enterovirus (n=5), cytomegalovirus (n=4), adenovirus (n=3), herpes simplex virus (n=2), Epstein-Barr virus (n=1), influenza A (n=2), and influenza B (n=1). All 7 cases of myocarditis amplified the same viral genome from heart as found by tracheal aspirate. CONCLUSIONS: PCR is a rapid and sensitive diagnostic tool in cases of viral pneumonia with or without myocarditis, and tracheal aspirate appears to be excellent for analysis. (+info)Oxidized low-density lipoproteins induce apoptosis in aortic and endocardial endothelial cells. (8/971)
AIM: To examine whether oxidized low-density lipoproteins (ox-LDL) might induce apoptosis in bovine aortic and endocardial endothelial cells (BAEC and BEEC). METHODS: Low-density lipoproteins (LDL) were isolated from healthy human plasma by ultracentrifugation and oxidized by CuSO4 10 mumol.L-1. BAEC and BEEC were incubated in a medium containing ox-LDL, LDL, or phosphate-buffer solution (PBS) as control. DNA fragmentation was visualized by agarose gel electrophoresis and determined quantitatively using Hoechst-33258 fluorochrome. RESULTS: Ox-LDL, not LDL, elicited typical apoptotic changes and DNA fragmentation in BAEC and BEEC. In BAEC, dextran sulfate, and cicloheximide (Cic) exhibited no effect on DNA fragmentation induced by ox-LDL. Butylated hydroxytoluene (BHT) 20 mumol.L-1 completely inhibited Cu(2+)-mediated oxidation of LDL as well as the apoptosis-inducing effect of Cu(2+)-exposed LDL. Lysophosphatidylcholine (LPC) did not elicit DNA fragmentation in BAEC and in BEEC. DNA fragmentation induced by ox-LDL in BAEC and in BEEC was blocked by chelating the calcium of the culture medium by egtazic acid. CONCLUSION: Ox-LDL induces apoptosis in BAEC and BEEC without involving the LPC. (+info)
Endocardial cushion tissue development: structural analyses on the attachment of extracellular matrix to migrating mesenchymal...
Validation of a New Noncontact Catheter System for Electroanatomic Mapping of Left Ventricular Endocardium | Circulation
Heterogeneity of the action potential in isolated rat ventricular myocytes and tissue. | Circulation Research
Expression of natriuretic peptide in ventricular myocardium of failing human hearts and its correlation with the severity of...
The heart endocardium is derived from vascular endothelial progenitors
Comparative Evaluation of Left and Right Ventricular Endomyocardial Biopsy | Circulation
Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial...
Myocardium and BMP signaling are required for endocardial differentiation | Development
Computational Cardiology: The Heart of the Matter : Figure 2
Differences in the electrophysiological response of canine ventricular subendocardium and subepicardium to acetylcholine and...
Average visual score for endocardial border delineation | Open-i
Sites of Focal Atrial Activity Characterized by Endocardial Mapping During Atrial Fibrillation | JACC: Journal of the American...
Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: insights into arrhythmogenesis in...
Endocardium
Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase -ORCA
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function |...
Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC. | [email protected]
EKG - Ischemia - ransquared
Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial...
What is the culprit artery? Not what you think.
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Influence of the Purkinje-muscle junction on transmural repolarization heterogeneity
Cardiac Pathology Section 10- Ischemic EKG Changes - Physeo
Washington Drugs: Sildenafil stada aussehen no prescription meds!
Endocardium Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Usefulness of electrophysiologic study and endomyocardial biopsy in differentiating arrhythmogenic right ventricular dysplasia...
Endocardial Fibroelastosis Differential Diagnoses
Purkinje-muscle coupling and endocardial response to hyperkalemia, hypoxia, and acidosis<...
Is the chest pain in cardiac syndrome X due to subendocardial ischaemia?<...
Detection of Subendocardial Ischemia in the Left Anterior Descending Coronary Artery Territory With Real-Time Myocardial...
C38.0 Malignant tumor of myocardium
Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesis in vitro | Development | The...
Angiographic correlations of patients with small vessel disease diagnosed by adenosine-stress cardiac magnetic resonance imaging
Two distinct pools of mesenchyme contribute to the development of the atrial septum. - Oxford Cardiovascular Science
Journal of The Indian Academy of Echocardiography & Cardiovascular Imaging : Table of Contents
Complications of myocardial infarction - Cardiac Output
What are the names of three layers of the heart wall? - Nursing tutors near me
Simulation studies of the ischemic vulnerability of the subendocardium » Brill Online
Meddygfa Victoria Surgery - Library - Health A-Z
Endocardial Surface Area Tracking for Assessment of Regional LV Wall Deformation With 3D Speckle Tracking Imaging | JACC:...
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Myocardial Border Tracking
In The Heart
Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging - Full Text View ...
Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging - Full Text View -...
Uncategorized | wave front ac
Carnegie Stage 17-3 - Reconstruction of the endocardium of the heart and its arterial trunks in embryo No. 6520
Regional electrophysiological effects of left ventricular hypertrophy in isolated rabbit hearts under normal and ischaemic...
glossary:endocarditis
The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation
Subendocardial mineralization | definition of subendocardial mineralization by Medical dictionary
Subendocardial - Definition of Subendocardial by Webster Dictionary
Epicardial and endocardial ST potential mapping in ischaemia - Open Access Repository
Coronary Blood Flow and Myocardial Ischemia | Cardiology Board Review and Self-Assessment: A Companion Guide to Hursts the...
An approach to endomyocardial biopsy interpretation | Journal of Clinical Pathology
Intracardiac electrode detection of early ischaemia in man. | Heart
Repetitive endocardial focal discharges during ventricular fibrillation with prolonged global ischemia in isolated rabbit...
SCVP Endomyocardial Biopsy Tutorial
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Diseases of the Myocardium, Pericardium, and Endocardium | SpringerLink
ICD-10 Diagnosis Code I09.1 Rheumatic diseases of endocardium, valve unspecified
Nitric-oxide-mediated regulation of cardiac contractility and stretch responses. - Oxford Cardiovascular Science
3D fusion echocardiography improves 3d left ventricular assessment: Comparison with 2d contrast echocardiography - Radcliffe...
Five Primary Patterns of Ischemic ST depression, without ST elevation. Some are STEMI-equivalents.
Five Primary Patterns of Ischemic ST depression, without ST elevation. Some are STEMI-equivalents.
Equal stroke volumes, different costs: left ventricular 4D flow in normal and failing hearts | Springer for Research &...
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Tissue - Simple English Wikipedia, the free encyclopedia
Tissue - Simple English Wikipedia, the free encyclopedia
Tissue - Simple English Wikipedia, the free encyclopedia
Endocarditis - Diagnosis and treatment - Mayo Clinic
Endocarditis - Doctors and departments - Mayo Clinic
Medicina | Free Full-Text | Changes of heart geometry in patients with ischemic heart disease
EPICARDIUM // gold - Covet + Keep
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endocardia - Wiktionary
Endocardium - Wikipedia
The endocardium also provides protection to the valves and heart chambers. The endocardium underlies the much more voluminous ... In infective endocarditis, the endocardium (especially the endocardium lining the heart valves) is affected by bacteria. Heart ... The endocardium is the innermost layer of tissue that lines the chambers of the heart. Its cells are embryologically and ... The endocardium, which is primarily made up of endothelial cells, controls myocardial function. This modulating role is ...
Diseases of the Myocardium, Pericardium, and Endocardium | SpringerLink
Regional Differences in Electrophysiological Properties of Epicardium, Midmyocardium, and Endocardium | Circulation
... and endocardium (13.3±0.7 minutes) than in midmyocardium (2.6±0.4 minutes; P,.05 compared with endocardium and epicardium). ... The APD-rate relationship of M cells is considerably steeper than that of epicardium and endocardium and more akin to that of ... Plunge recordings from the endocardium were made with two Teflon-coated stainless steel wires (0.1-mm diameter).17 The wires ... This suggests that in settings of Ca2+ overload, the difference between midmyocardium and epicardium and endocardium may be ...
Does structure "D" represent the endocardium? - ProProfs Discuss
While it is not the endocardium, D represents the aortic semilunar valve. This valve is in the human heart. It is between the ... Does structure "D" represent the endocardium?. This question is part of Unit IV: Anatomy of the Heart & Blood Vessels. Asked by ... While it is not the endocardium, "D" represents the aortic semilunar valve. This valve is in the human heart. It is between the ...
Origins and patterning of avian outflow tract endocardium | Development
Outflow tract endocardium links the atrioventricular lining, which develops from cardiogenic plate mesoderm, with aortic arches ... The objectives of this research were to document the history of outflow tract endocardium in the avian embryo immediately prior ... Precursors of outflow tract but not atrioventricular endocardium are present in cephalic paraxial and lateral mesoderm, with ... outflow tract endocardial cells participate in morphogenetic events not within the repertoire of neighboring endocardium: they ...
Validation of a New Noncontact Catheter System for Electroanatomic Mapping of Left Ventricular Endocardium | Circulation
Validation of a New Noncontact Catheter System for Electroanatomic Mapping of Left Ventricular Endocardium. Charles C. Gornick ... However, they noted a 10° rotational error in defining the position of the probe relative to the endocardium, which yielded an ... Top left, Color-coded (white [most negative] to purple [most positive]) isopotential map of LV endocardium with activation ... Validation of a New Noncontact Catheter System for Electroanatomic Mapping of Left Ventricular Endocardium ...
Frontiers | Solving the Inverse Problem of Electrocardiography on the Endocardium Using a Single Layer Source | Physiology
This paper presents a novel numerical approach aimed at improving the solution quality on the endocardium. Our method exploits ... The proposed approach provided more accurate solution on the ventricular endocardium compared to the conventional potential- ... The proposed approach provided more accurate solution on the ventricular endocardium compared to the conventional potential- ... This paper presents a novel numerical approach aimed at improving the solution quality on the endocardium. Our method exploits ...
Reconstitution of the Ventricular Endocardium Within Acellular Hearts | SpringerLink
The endocardium. Annu Rev Physiol. 1989;51:263-73.CrossRefGoogle Scholar ... OKADA R. Clinicopathological study on the thickening of parietal endocardium in the adult heart. Jpn Heart J. 1961;2:220-55. ... Nagayo M. Zur normalen und pathologischen Histologie des Endocardium parietale. Berlin: G Fischer; 1909.Google Scholar ... These results indicate that layer-by-layer deposition can aid in the reconstitution of the cardiac endocardium. ...
Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart
Using 3D whole-mount imaging, we reveal a highly dynamic endocardium during cardiac regeneration, including changes in cell ... Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart ... serpine1 is strongly expressed very early in the wound endocardium, with decreasing expression at later time points. serpine1 ... These events lay the foundation for an initial expansion of the endocardium that matures to form a coherent endocardial ...
GATA-4 is a novel transcription factor expressed in endocardium of the developing heart | Development
GATA-4 is a novel transcription factor expressed in endocardium of the developing heart ... GATA-4 is a novel transcription factor expressed in endocardium of the developing heart ... GATA-4 is a novel transcription factor expressed in endocardium of the developing heart ... GATA-4 is a novel transcription factor expressed in endocardium of the developing heart ...
Frontiers | Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium...
... were determined in rat sub-endocardium (Endo) and sub-epicardium (Epi). Further, the effect of a direct NO donor (MAHMA NONOate ... were determined in rat sub-endocardium (Endo) and sub-epicardium (Epi). Further, the effect of a direct NO donor (MAHMA NONOate ... respiration transmural gradient is likely related to NO and possibly ROS increased production in the sub-endocardium. ... However, to date, the physiological mechanisms involved in the lower endocardium mitochondrial respiration chain capacity still ...
endocardium - oi
Ticagrelor, but not clopidogrel active metabolite, displays antithrombotic properties in the left atrial endocardium ... Computerized evaluation of echocardiographic stress tests in patients with poorly visualized endocardium using analysis of ... Electrophysiological responses of canine atrial endocardium and epicardium to acetylcholine and 4-aminopyridine ... Transmural repolarization gradients in vivo: the flukes and falls of the endocardium ...
Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory...
Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory ... Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory ... Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory ... Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory ...
Carnegie Stage 17-3 - Reconstruction of the endocardium of the heart and its arterial trunks in embryo No. 6520
Reconstruction of the endocardium of the heart and its arterial trunks in No. 6520, a member of the median third of stage 17. ... Reconstruction of the endocardium of the heart and its arterial trunks in embryo No. 6520. ... From the distention of the endocardium of the primary cardiac tube, however, one can see that the left ventricle favors the ... Keywords: aorta, aortic semilunar valve, arterial trunk, atrioventricular junction, endocardium, interseptal space, left ...
Segmentation of the left ventricular endocardium from magnetic resonance images by using different statistical shape models -...
Segmentation of the left ventricular endocardium from magnetic resonance images by using different statistical shape models ... Download PDF Segmentation of the left ventricular endocardium from magnetic resonance images by using different statistical ... approach to segment the LV endocardium in CMR images of 45 patients. Segmentation performance was evaluated by comparing LV ... approach to segment the LV endocardium in CMR images of 45 patients. Segmentation performance was evaluated by comparing LV ...
Epicardial phenol interrupts refractory period responses to sympathetic but not vagal stimulation in canine left ventricular...
... refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium.. J ... refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium. ... refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium. ... refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium. ...
Regional dynamics of fractal dimension of the left ventricular endocardium from cine computed tomography images.
The topography of the endocardium is characterized by its regional values of fractal dimension ( FD ), computed using a box- ... to quantify regional left ventricular function using topography variation of the endocardium as a surrogate measure of strain. ... The topography of the endocardium is characterized by its regional values of fractal dimension ( FD ), computed using a box- ... to quantify regional left ventricular function using topography variation of the endocardium as a surrogate measure of strain. ...
Heart failure in infancy with abnormalities of the valves and endocardium. - Semantic Scholar
Endocardium
The endocardium also provides protection to the valves and heart chambers. The endocardium underlies the much more voluminous ... In infective endocarditis, the endocardium (especially the endocardium lining the heart valves) is affected by bacteria. ... The endocardium is the innermost layer of tissue that lines the chambers of the heart. Its cells are embryologically and ... Wikimedia Commons has media related to Endocardium.. This article uses anatomical terminology; for an overview, see anatomical ...
Endocardium
endocardium Archives - CriticalCareDVM
glossary:endocardium [Lymphedema People]
Human Physiology/The cardiovascular system - Wikibooks, open books for an open world
Endocardium[edit]. The endocardium is the innermost lining of the heart which consists of the endothelial cells forming a ... Purkinje Fibers (or Purkinje tissue): located in the inner ventricular walls of the heart, just beneath the endocardium; ... This is the outer layer after endocardium and myocardium that consists of a thin layer of connective tissue and fat. ... Purkinje fibers (or Purkyne tissue) are located in the inner ventricular walls of the heart, just beneath the endocardium. ...
ICD-10-CM Neoplasms Index - Endocardium
Endocardium - Interactive Biology, with Leslie Samuel
Layers of the Heart - Epicardium, Myocardium, Endocardium | Kenhub
... the myocardium and the endocardium. Learn all about them at Kenhub! ... It sits between the inner endocardium and the outer epicardium.. Endocardium. The endocardium is the most inner layer of the ... The endocardium. Each layer has a different function, which primarily aids the pumping action of the heart which allows the ... Endocardium - histological slide - Smart In Media. © Unless stated otherwise, all content, including illustrations are ...
Cardiac Myxoma (Endocardium Myxoma): Symptoms, Diagnosis and Treatment - Symptoma
Endocardium Myxoma): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. ... Endocardium Myxoma. Cardiac myxomas are benign soft tissue tumors occurring more frequently in women than in men. Although they ... Pathophysiology Originate from the endocardium. [pie.med.utoronto.ca] (Etiology) The cause of development of Cardiac Myxoma is ... Mckenna WJ, Elliott P. Diseases of the myocardium and endocardium. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ...
The heart endocardium is derived from vascular endothelial progenitors
... the origins of the endocardium remain unclear. Here, we have identified an endocardium-forming field medial to the cardiac ... The heart endocardium is derived from vascular endothelial progenitors Academic Article * View record in Web of Science ® ... Furthermore, embryonic endothelial cells implanted into the cardiac crescent contribute to the endocardium, but not to the ... We suggest that the endocardium derives, at least in part, from vascular endothelial cells. ...
Endocardium Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
MalaCards based summary : Endocardium Disease, also known as abnormality of the endocardium, is related to endocarditis and ... MalaCards organs/tissues related to Endocardium Disease:. 40 Heart, Bone, Kidney, Lung, Liver, Skin, Eye ... Articles related to Endocardium Disease:. #. Title. Authors. PMID. Year. 1. The fetal heart: a practical sonographic approach. ... Pathways related to Endocardium Disease according to GeneCards Suite gene sharing:. #. Super pathways. Score. Top Affiliating ...
Endothelial cellsMyocardium and endocardiumInflammationInnermostEndotheliumEpicardium and endocardiumEmbryoVentricular endocardiumTissueMyocardialEndocarditisAtriaAortic semilPericardiumThrombus formationPurkinjeHeart chambersVentriclesValvesDiseasesOuter layerValveMorphogeneticRepolarizationInterventricularLayer of the heartPrimarilyCanineDiseaseContentBloodRepresentsˌɛnEmbryonicHeterogeneityLeftBundlesThin
Endothelial cells5
- The endocardium, which is primarily made up of endothelial cells, controls myocardial function. (wikipedia.org)
- The endocardium is the innermost lining of the heart which consists of the endothelial cells forming a smooth membrane in places, and a pocked and tribeculated surface in others (mainly the ventricles, or lower pumping chambers). (wikibooks.org)
- Furthermore, embryonic endothelial cells implanted into the cardiac crescent contribute to the endocardium, but not to the myocardium. (edu.au)
- We suggest that the endocardium derives, at least in part, from vascular endothelial cells. (edu.au)
- Furthermore, the endothelial cells found in the endocardium not only cover the walls of the chambers of the heart but also that of the valves. (infobarrel.com)
Myocardium and endocardium5
- The heart wall is divided into three layers: epicardium, myocardium, and endocardium. (thoughtco.com)
- Mckenna WJ, Elliott P. Diseases of the myocardium and endocardium. (symptoma.com)
- The heart wall is made of 3 layers: epicardium, myocardium and endocardium. (innerbody.com)
- The heart consists of three layers: epicardium, myocardium and endocardium. (histology-world.com)
- The myocardium and endocardium arise from fusion of two bilateral fields of cardiac precursor cells in the anterior lateral plate mesoderm (the first heart field), and subsequent recruitment and delayed myocardial differentiation of pharyngeal mesoderm (the second heart field) [ 1 ]. (mdpi.com)
Inflammation3
- Inflammation of the endocardium is called endocarditis. (thefreedictionary.com)
- Inflammation of the endocardium. (thefreedictionary.com)
- Inflammation of the endocardium (inner heart lining) often resulting from infection by bacteria. (thefreedictionary.com)
Innermost2
- The endocardium is the innermost layer of tissue that lines the chambers of the heart. (wikipedia.org)
- The innermost portion of the endocardium is composed of endothelium, a simple squamous epithelium. (histology-world.com)
Endothelium3
- Ablation of Flk1 coupled with lineage analysis in the Isl1 lineage revealed that endothelium-derived Isl1(-) endocardial cells were significantly increased, whereas Isl1(+) endocardial cells were reduced, suggesting that the endocardium is capable of undergoing regulative compensatory growth. (edu.au)
- Platelet adhesion/thrombus formation in the endocardium was found in limited sites in which the overlying endothelium was deficient in eNOS and CD34. (onlinejacc.org)
- Endocardium is the simple squamous endothelium layer that lines the inside of the heart. (innerbody.com)
Epicardium and endocardium2
- The APD-rate relationship of M cells is considerably steeper than that of epicardium and endocardium and more akin to that of Purkinje fibers. (ahajournals.org)
- Epicardial phenol interrupts refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium. (ahajournals.org)
Embryo3
- The objectives of this research were to document the history of outflow tract endocardium in the avian embryo immediately prior to development of the heart, and to ascertain which, if any, aspects of this history are necessary to acquire cushion-forming potential. (biologists.org)
- Endocardium and myocardium, i.e. the inner and the muscular layer of the heart, are present in the simple peristaltically active tube that is established shortly after gastrulation to support the need of the rapidly growing embryo. (mdpi.com)
- Her presenterer vi en protokoll for å samle inn funksjonelle / bankende hjerter ved rask manuell disseksjon fra sebrafisk embryo for å få hjertespesifikke mRNA. (jove.com)
Ventricular endocardium4
- The proposed approach provided more accurate solution on the ventricular endocardium compared to the conventional potential-based solutions with Tikhonov regularization of the 0th, 1st, and 2nd orders. (frontiersin.org)
- Regional dynamics of fractal dimension of the left ventricular endocardium from cine computed tomography images. (escholarship.org)
- Modified design of stimulation of the left ventricular endocardium for cardiac resynchronization therapy in nonresponders, previously untreatable and high-risk upgrade patients (SOLVE-CRT) trial. (bvsalud.org)
- Safety and efficacy were being evaluated in the pivotal, randomized, double-blind SOLVE-CRT Trial (Stimulation of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy . (bvsalud.org)
Tissue12
- The endocardium underlies the much more voluminous myocardium, the muscular tissue responsible for the contraction of the heart. (wikipedia.org)
- The inner surfaces of the heart s chambers are lined with a thin sheet of shiny, white tissue known as the endocardium. (50webs.com)
- This is the outer layer after endocardium and myocardium that consists of a thin layer of connective tissue and fat. (wikibooks.org)
- The embryonic heart is composed of two cell layers: the myocardium, which contributes to cardiac muscle tissue, and the endocardium, which covers the inner lumen of the heart. (edu.au)
- The middle layer of the endocardium is connective tissue and smooth muscle. (histology-world.com)
- Ultrastructural changes in the secretory organelles of endocardium and endocardial cushion tissue. (musc.edu)
- Endocardium and endocardial cushion tissue from 12.5 and 14.5 day embryonic rat hearts exposed to sodium salicylate or 6-aminonicotinamide were compared electron microscopically with non-injected or parahydroxybenzoic acid-treated control tissue . (musc.edu)
- The purpose of these comparisons was to test a working hypothesis which purports that cardiac septal defects are causally related to an inhibition of acid mucopolysaccharide synthesis within endocardium and the subjacent cushion tissue . (musc.edu)
- Conversely , endocardium overlying cushion tissue exhibited hypertrophy of the secretory organelles and associated cytoplasm resulting in a scalloped appearance . (musc.edu)
- The two teratogens apparently inhibited secretory potential by inducing regressions or alterations of the secretory organelles of endocardium and the associated cushion tissue . (musc.edu)
- These alterations took the form of " honeycombl distensions within the otherwise non-dilated cisternae of rough endoplasmic reticulum (RER) of endocardium overlying cushion tissue , a feature normally seen only in control trabeculated endocardium . (musc.edu)
- The endocardium is the inner most layer of the heart and is made up of epithelial tissue. (brighthub.com)
Myocardial3
- In myocardial infarction, ischemia of the myocardium can extend to the endocardium, disrupting the inner lining of the heart ("transmural" infarction). (wikipedia.org)
- The endocardium was found to undergo a biphasic pattern of cytodifferentiation in which endocardium associated with myocardial trabeculae displayed atrophy of secretory organelles and attenuation of cytoplasm . (musc.edu)
- Later, at E11, a second wave of calcineurin/NFAT signaling is required in the endocardium, adjacent to the earlier myocardial site of NFAT action, to direct valvular elongation and refinement. (nih.gov)
Endocarditis5
- In infective endocarditis, the endocardium (especially the endocardium lining the heart valves) is affected by bacteria. (wikipedia.org)
- An infection of the endocardium can lead to a condition known as endocarditis. (thoughtco.com)
- Endocarditis is typically the result of an infection of the heart valves or endocardium by certain bacteria , fungi , or other microbes. (thoughtco.com)
- Endocardium Disease, also known as abnormality of the endocardium , is related to endocarditis and endocardial fibroelastosis . (malacards.org)
- Endocarditis is a rare and potentially fatal infection of the inner lining of the heart (the endocardium). (everydayhealth.com)
Atria1
- The endocardium of heart atria consists of smooth muscle, as well as elastic fibers. (thoughtco.com)
Aortic semil1
- While it is not the endocardium, "D" represents the aortic semilunar valve. (proprofs.com)
Pericardium4
- Oakley C.M. (1984) Diseases of the Myocardium, Pericardium, and Endocardium. (springer.com)
- Why is pericardium muscle repolarizated earlier than endocardium? (stackexchange.com)
- The endocardium depolarization happens earlier than pericardium , but pericarduim repolarization happens earlier, therefore the T wave in healthy people is always positive. (stackexchange.com)
- Points : 1) Epicardium Pericardium Myocardium Endocardium Hypocardium 2. (bartleby.com)
Thrombus formation1
- When warfarin-treated cases were excluded, there was a significant correlation between the immunohistochemical grade for vWF and the degree of platelet adhesion/thrombus formation in the endocardium. (onlinejacc.org)
Purkinje1
- Another thing to note in relation to the endocardium is that the Purkinje fibres are located in this layer of heart. (infobarrel.com)
Heart chambers3
- The endocardium also provides protection to the valves and heart chambers. (wikipedia.org)
- 1) Endocardium: The lining of the interior surface of the [[heart]] chambers. (lymphedemapeople.com)
- an inflamed condition of the endocardium, the membrane that lines heart chambers. (thefreedictionary.com)
Ventricles1
- The effect of E a on endocardium and epicardium was studied on Langendorff-perfused, di-4-ANEPPS stained isolated rabbit right ventricles (RV) to which a 10-40 V/cm E a was applied from plate electrodes inside a Tyrode's bath. (nctu.edu.tw)
Valves2
- Heart failure in infancy with abnormalities of the valves and endocardium. (semanticscholar.org)
- The heart valves and the chambers are lined with endocardium . (wikipedia.org)
Diseases1
- Diseases associated with SH3BP5 include Endocardium Disease and Agammaglobulinemia, X-Linked 1 . (genecards.org)
Outer layer2
- The outer layer of the endocardium is the subendocardial layer. (histology-world.com)
- The outer layer is the epicardium, the middle layer is the myocardium and the inner most layer is the endocardium. (brighthub.com)
Valve1
- Thus, NFAT signaling functions sequentially from myocardium to endocardium within a valvular morphogenetic field to initiate and perpetuate embryonic valve formation. (nih.gov)
Morphogenetic1
- At two discrete sites, outflow tract endocardial cells participate in morphogenetic events not within the repertoire of neighboring endocardium: they form mesenchymal precursors of endocardial cushions. (biologists.org)
Repolarization1
- During depolarization the impulse is carried from endocardium to epicardium, and during repolarization the impulse moves from epicardium to endocardium. (wikipedia.org)
Interventricular1
- Unfortunately, epicardial imaging bears one significant limitation of potentially losing electrophysiologically relevant information about cardiac electrical activity on the cardiac endocardium and, especially, on the interventricular and interatrial septum. (frontiersin.org)
Layer of the heart4
- Using these systems, we successfully reconstituted an important internal layer of the heart, the endocardium, lining the cavities of the heart, with most cells remaining alive and active. (springer.com)
- Endocardium -inner layer of the heart. (thoughtco.com)
- Endocardium (endo-cardium) is the thin inner layer of the heart wall. (thoughtco.com)
- The endocardium is situated in the inner layer of the heart and it covers fibrous skeletons of the heart. (infobarrel.com)
Primarily1
- The endocardium is primarily responsible for myocardium function. (brighthub.com)
Canine1
- 7 Differences in action potential characteristics, similar to those described in syncytial preparations, have also been found in single myocytes isolated from the epicardium, M region, and endocardium of the canine ventricular free wall. (ahajournals.org)
Disease1
- An important gene associated with Endocardium Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Selenium Micronutrient Network and Overview of nanoparticle effects . (malacards.org)
Content1
- Maximal oxidative capacity (V Max ) and relative contributions of the respiratory chain complexes II, III, IV (V Succ ) and IV (V TMPD ), mitochondrial content (citrate synthase activity), coupling, NO (electron paramagnetic resonance), and reactive oxygen species (ROS) production (H 2 O 2 and dihydroethidium (DHE) staining) were determined in rat sub-endocardium (Endo) and sub-epicardium (Epi). (frontiersin.org)
Blood4
- This is a false-color scanning electron micrograph (SEM) showing an aggregation of red blood cells on the endocardium, the lining of the heart. (thoughtco.com)
- The endocardium is very smooth and is responsible for keeping blood from sticking to the inside of the heart and forming potentially deadly blood clots. (innerbody.com)
- The endocardium contains blood vessels. (histology-world.com)
- The endocardium is continuous with the endothelial coating of the blood vessels that leaves and enters the heart. (infobarrel.com)
Represents1
- The endocardium represents number three of the layers of the heart. (infobarrel.com)
ˌɛn1
- ˌɛn doʊˈkɑr diˌæk) of or pertaining to the endocardium. (thefreedictionary.com)
Embryonic1
- Whereas significant progress has been made toward elucidating the embryonic origins of the myocardium, the origins of the endocardium remain unclear. (edu.au)
Heterogeneity1
- In mouse, lineage analysis focusing on endocardial cells revealed an unexpected heterogeneity in the origins of the endocardium. (edu.au)
Left5
- This study validated a new noncontact multielectrode array catheter and accompanying analysis system to provide electroanatomic mapping of the entire left ventricular (LV) endocardium during a single beat. (ahajournals.org)
- This study validated the use of a noncontact, multielectrode array catheter (EnSite) and analysis system (EnSite 3000 System, Endocardial Solutions Inc) to provide electrophysiological and anatomic mapping of the entire left ventricular (LV) endocardium in a single beat. (ahajournals.org)
- From the distention of the endocardium of the primary cardiac tube, however, one can see that the left ventricle favors the aorta and the right ventricle the pulmonary trunk. (ehd.org)
- We present a method to leverage the high fidelity of computed tomography (CT) to quantify regional left ventricular function using topography variation of the endocardium as a surrogate measure of strain. (escholarship.org)
- 3 . The method of claim 1 , wherein the target boundaries comprise the endocardium and epicardium of the left ventricle of the heart. (google.com)
Bundles1
- Electroporation was voltage dependent and significantly more pronounced at the endocardium versus the epicardium, with thresholds of 229±81 versus 318±84 V, respectively ( P =0.01, n=10), both being above the defibrillation threshold of 181.3±45.8 V. Epicardial electroporation was localized to a small area near the electrode, whereas endocardial electroporation was observed at the bundles and trabeculas throughout the entire endocardium. (ahajournals.org)
Thin1
- Below the myocardium is the thin endocardium layer. (innerbody.com)