A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), found in Australia and New Guinea. It causes a fulminating viremia resembling Japanese encephalitis (ENCEPHALITIS, JAPANESE).
Infections of the brain caused by arthropod-borne viruses (i.e., arboviruses) primarily from the families TOGAVIRIDAE; FLAVIVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; and RHABDOVIRIDAE. Life cycles of these viruses are characterized by ZOONOSES, with birds and lower mammals serving as intermediate hosts. The virus is transmitted to humans by the bite of mosquitoes (CULICIDAE) or TICKS. Clinical manifestations include fever, headache, alterations of mentation, focal neurologic deficits, and COMA. (From Clin Microbiol Rev 1994 Jan;7(1):89-116; Walton, Brain's Diseases of the Nervous System, 10th ed, p321)
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), which is the etiological agent of Japanese encephalitis found in Asia, southeast Asia, and the Indian subcontinent.
A genus of FLAVIVIRIDAE containing several subgroups and many species. Most are arboviruses transmitted by mosquitoes or ticks. The type species is YELLOW FEVER VIRUS.
A collection of single-stranded RNA viruses scattered across the Bunyaviridae, Flaviviridae, and Togaviridae families whose common property is the ability to induce encephalitic conditions in infected hosts.
A mosquito-borne encephalitis caused by the Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE) occurring throughout Eastern Asia and Australia. The majority of infections occur in children and are subclinical or have features limited to transient fever and gastrointestinal symptoms. Inflammation of the brain, spinal cord, and meninges may occur and lead to transient or permanent neurologic deficits (including a POLIOMYELITIS-like presentation); SEIZURES; COMA; and death. (From Adams et al., Principles of Neurology, 6th ed, p751; Lancet 1998 Apr 11;351(9109):1094-7)
A species of ALPHAVIRUS that is the etiologic agent of encephalomyelitis in humans and equines. It is seen most commonly in parts of Central and South America.
A subgroup of the genus FLAVIVIRUS that causes encephalitis and hemorrhagic fevers and is found in eastern and western Europe and the former Soviet Union. It is transmitted by TICKS and there is an associated milk-borne transmission from viremic cattle, goats, and sheep.
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), which is the etiologic agent of ST. LOUIS ENCEPHALITIS in the United States, the Caribbean, and Central and South America.
Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
A species of ALPHAVIRUS causing encephalomyelitis in Equidae and humans. The virus ranges along the Atlantic seaboard of the United States and Canada and as far south as the Caribbean, Mexico, and parts of Central and South America. Infections in horses show a mortality of up to 90 percent and in humans as high as 80 percent in epidemics.
A species of ALPHAVIRUS that is the etiologic agent of encephalomyelitis in humans and equines in the United States, southern Canada, and parts of South America.
Inflammation of brain parenchymal tissue as a result of viral infection. Encephalitis may occur as primary or secondary manifestation of TOGAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; BUNYAVIRIDAE INFECTIONS; PICORNAVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RETROVIRIDAE INFECTIONS; and ARENAVIRIDAE INFECTIONS.
Infections with viruses of the genus FLAVIVIRUS, family FLAVIVIRIDAE.
Arthropod-borne viruses. A non-taxonomic designation for viruses that can replicate in both vertebrate hosts and arthropod vectors. Included are some members of the following families: ARENAVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; TOGAVIRIDAE; and FLAVIVIRIDAE. (From Dictionary of Microbiology and Molecular Biology, 2nd ed)
A viral encephalitis caused by the St. Louis encephalitis virus (ENCEPHALITIS VIRUS, ST. LOUIS), a FLAVIVIRUS. It is transmitted to humans and other vertebrates primarily by mosquitoes of the genus CULEX. The primary animal vectors are wild birds and the disorder is endemic to the midwestern and southeastern United States. Infections may be limited to an influenza-like illness or present as an ASEPTIC MENINGITIS or ENCEPHALITIS. Clinical manifestations of the encephalitic presentation may include SEIZURES, lethargy, MYOCLONUS, focal neurologic signs, COMA, and DEATH. (From Adams et al., Principles of Neurology, 6th ed, p750)
A form of arboviral encephalitis endemic to Central America and the northern latitudes of South America. The causative organism (ENCEPHALITIS VIRUS, VENEZUELAN EQUINE) is transmitted to humans and horses via the bite of several mosquito species. Human viral infection may be asymptomatic or remain restricted to a mild influenza-like illness. Encephalitis, usually not severe, occurs in a small percentage of cases and may rarely feature SEIZURES and COMA. (From Joynt, Clinical Neurology, 1996, Ch26, pp9-10)
Encephalitis caused by neurotropic viruses that are transmitted via the bite of TICKS. In Europe, the diseases are caused by ENCEPHALITIS VIRUSES, TICK-BORNE, which give rise to Russian spring-summer encephalitis, central European encephalitis, louping ill encephalitis, and related disorders. Powassan encephalitis occurs in North America and Russia and is caused by the Powassan virus. ASEPTIC MENINGITIS and rarely encephalitis may complicate COLORADO TICK FEVER which is endemic to mountainous regions of the western United States. (From Joynt, Clinical Neurology, 1996, Ch26, pp14-5)
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE). It can infect birds and mammals. In humans, it is seen most frequently in Africa, Asia, and Europe presenting as a silent infection or undifferentiated fever (WEST NILE FEVER). The virus appeared in North America for the first time in 1999. It is transmitted mainly by CULEX spp mosquitoes which feed primarily on birds, but it can also be carried by the Asian Tiger mosquito, AEDES albopictus, which feeds mainly on mammals.
An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.
A group of ALPHAVIRUS INFECTIONS which affect horses and man, transmitted via the bites of mosquitoes. Disorders in this category are endemic to regions of South America and North America. In humans, clinical manifestations vary with the type of infection, and range from a mild influenza-like syndrome to a fulminant encephalitis. (From Joynt, Clinical Neurology, 1996, Ch26, pp8-10)
A country consisting of the eastern half of the island of New Guinea and adjacent islands, including New Britain, New Ireland, the Admiralty Islands, and New Hanover in the Bismarck Archipelago; Bougainville and Buka in the northern Solomon Islands; the D'Entrecasteaux and Trobriand Islands; Woodlark (Murua) Island; and the Louisiade Archipelago. It became independent on September 16, 1975. Formerly, the southern part was the Australian Territory of Papua, and the northern part was the UN Trust Territory of New Guinea, administered by Australia. They were administratively merged in 1949 and named Papua and New Guinea, and renamed Papua New Guinea in 1971.
Immunoglobulins produced in response to VIRAL ANTIGENS.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
Vaccines or candidate vaccines used to prevent infection with Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE).
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
A subgroup of the genus FLAVIVIRUS which comprises a number of viral species that are the etiologic agents of human encephalitis in many different geographical regions. These include Japanese encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE), St. Louis encephalitis virus (ENCEPHALITIS VIRUS, ST. LOUIS), Murray Valley encephalitis virus (ENCEPHALITIS VIRUS, MURRAY VALLEY), and WEST NILE VIRUS.
A paraneoplastic syndrome marked by degeneration of neurons in the LIMBIC SYSTEM. Clinical features include HALLUCINATIONS, loss of EPISODIC MEMORY; ANOSMIA; AGEUSIA; TEMPORAL LOBE EPILEPSY; DEMENTIA; and affective disturbance (depression). Circulating anti-neuronal antibodies (e.g., anti-Hu; anti-Yo; anti-Ri; and anti-Ma2) and small cell lung carcinomas or testicular carcinoma are frequently associated with this syndrome.
An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)
A family of the order DIPTERA that comprises the mosquitoes. The larval stages are aquatic, and the adults can be recognized by the characteristic WINGS, ANIMAL venation, the scales along the wing veins, and the long proboscis. Many species are of particular medical importance.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A genus of mosquitoes (CULICIDAE) commonly found in tropical regions. Species of this genus are vectors for ST. LOUIS ENCEPHALITIS as well as many other diseases of man and domestic and wild animals.
A form of arboviral encephalitis (primarily affecting equines) endemic to eastern regions of North America. The causative organism (ENCEPHALOMYELITIS VIRUS, EASTERN EQUINE) may be transmitted to humans via the bite of AEDES mosquitoes. Clinical manifestations include the acute onset of fever, HEADACHE, altered mentation, and SEIZURES followed by coma. The condition is fatal in up to 50% of cases. Recovery may be marked by residual neurologic deficits and EPILEPSY. (From Joynt, Clinical Neurology, 1996, Ch26, pp9-10)
A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), closely related to VISNA-MAEDI VIRUS and causing acute encephalomyelitis; chronic arthritis; PNEUMONIA; MASTITIS; and GLOMERULONEPHRITIS in goats. It is transmitted mainly in the colostrum and milk.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Diseases of domestic and wild horses of the species Equus caballus.
Process of growing viruses in live animals, plants, or cultured cells.
Ribonucleic acid that makes up the genetic material of viruses.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
A genus of TOGAVIRIDAE, also known as Group A arboviruses, serologically related to each other but not to other Togaviridae. The viruses are transmitted by mosquitoes. The type species is the SINDBIS VIRUS.
A mosquito-borne viral illness caused by the WEST NILE VIRUS, a FLAVIVIRUS and endemic to regions of Africa, Asia, and Europe. Common clinical features include HEADACHE; FEVER; maculopapular rash; gastrointestinal symptoms; and lymphadenopathy. MENINGITIS; ENCEPHALITIS; and MYELITIS may also occur. The disease may occasionally be fatal or leave survivors with residual neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13; Lancet 1998 Sep 5;352(9130):767-71)
Viruses whose genetic material is RNA.
The measurement of infection-blocking titer of ANTISERA by testing a series of dilutions for a given virus-antiserum interaction end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (CPE) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (ID50) or die (LD50).
Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
Substances elaborated by viruses that have antigenic activity.
A species in the ORTHOBUNYAVIRUS genus of the family BUNYAVIRIDAE. Serotypes are found in temperate and arctic regions and each is closely associated with a single species of vector mosquito. The vertebrate hosts are usually small mammals but several serotypes infect humans.
A viral infection of the brain caused by serotypes of California encephalitis virus (ENCEPHALITIS VIRUS, CALIFORNIA) transmitted to humans by the mosquito AEDES triseriatus. The majority of cases are caused by the LA CROSSE VIRUS. This condition is endemic to the midwestern United States and primarily affects children between 5-10 years of age. Clinical manifestations include FEVER; VOMITING; HEADACHE; and abdominal pain followed by SEIZURES, altered mentation, and focal neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13)
The relationships of groups of organisms as reflected by their genetic makeup.
Insects that transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.
Established cell cultures that have the potential to propagate indefinitely.
Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.
Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.
Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.
The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.
Disorder characterized by symptoms of CATATONIA; HYPOVENTILATION; DYSKINESIAS; ENCEPHALITIS; and SEIZURES followed by a reduced CONSCIOUSNESS. It is often followed by a viral-like prodrome. Many cases are self-limiting and respond well to IMMUNOMODULATORY THERAPIES against the NMDA RECEPTORS antibodies.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Infections caused by arthropod-borne viruses, general or unspecified.

The severity of murray valley encephalitis in mice is linked to neutrophil infiltration and inducible nitric oxide synthase activity in the central nervous system. (1/42)

A study of immunopathology in the central nervous system (CNS) during infection with a virulent strain of Murray Valley encephalitis virus (MVE) in weanling Swiss mice following peripheral inoculation is presented. It has previously been shown that virus enters the murine CNS 4 days after peripheral inoculation, spreads to the anterior olfactory nucleus, the pyriform cortex, and the hippocampal formation at 5 days postinfection (p.i.), and then spreads throughout the cerebral cortex, caudate putamen, thalamus, and brain stem between 6 and 9 days p.i. (P. C. McMinn, L. Dalgarno, and R. C. Weir, Virology 220:414-423, 1996). Here we show that the encephalitis which develops in MVE-infected mice from 5 days p.i. is associated with the development of a neutrophil inflammatory response in perivascular regions and in the CNS parenchyma. Infiltration of neutrophils into the CNS was preceded by increased expression of tumor necrosis factor alpha and the neutrophil-attracting chemokine N51/KC within the CNS. Depletion of neutrophils with a cytotoxic monoclonal antibody (RB6-8C5) resulted in prolonged survival and decreased mortality in MVE-infected mice. In addition, neutrophil infiltration and disease onset correlated with expression of the enzyme-inducible nitric oxide synthase (iNOS) within the CNS. Inhibition of iNOS by aminoguanidine resulted in prolonged survival and decreased mortality in MVE-infected mice. This study provides strong support for the hypothesis that Murray Valley encephalitis is primarily an immunopathological disease.  (+info)

Characterization of infectious Murray Valley encephalitis virus derived from a stably cloned genome-length cDNA. (2/42)

An infectious cDNA clone of Murray Valley encephalitis virus prototype strain 1-51 (MVE-1-51) was constructed by stably inserting genome-length cDNA into the low-copy-number plasmid vector pMC18. Designated pMVE-1-51, the clone consisted of genome-length cDNA of MVE-1-51 under the control of a T7 RNA polymerase promoter. The clone was constructed by using existing components of a cDNA library, in addition to cDNA of the 3' terminus derived by RT-PCR of poly(A)-tailed viral RNA. Upon comparison with other flavivirus sequences, the previously undetermined sequence of the 3' UTR was found to contain elements conserved throughout the genus FLAVIVIRUS: RNA transcribed from pMVE-1-51 and subsequently transfected into BHK-21 cells generated infectious virus. The plaque morphology, replication kinetics and antigenic profile of clone-derived virus (CDV-1-51) was similar to the parental virus in vitro. Furthermore, the virulence properties of CDV-1-51 and MVE-1-51 (LD(50) values and mortality profiles) were found to be identical in vivo in the mouse model. Through site-directed mutagenesis, the infectious clone should serve as a valuable tool for investigating the molecular determinants of virulence in MVE virus.  (+info)

Morphological features of Murray Valley encephalitis virus infection in the central nervous system of Swiss mice. (3/42)

We have examined the histological and ultrastructural features of CNS infection with Murray Valley encephalitis (MVE) virus in mice inoculated with a virulent parental strain (BH3479). Light microscopic examination revealed neuronal necrosis in the olfactory bulb and hippocampus of MVE-infected brains by 5 days post-infection (pi). Electron microscopy of these regions showed endoplasmic reticulum membrane proliferation, and tubular and spherical structures in the cisternae of the endoplasmic reticulum, Golgi complex and nuclear envelope. At seven to eight days pi, infected neurones exhibited chromatin condensation and extrusion, nuclear fragmentation, loss of segments of the nuclear envelope, reduced surface contact with adjacent cells and loss of cytoplasmic organelles. This cell injury was particularly noticeable in the proximal CA3 and distal CA1 regions of the hippocampus. The inflammatory cell profile consisted of macrophages, lymphocytes and especially neutrophils, and many of these inflammatory cells were apoptotic. High mortality rates in the BH3479-infected population of mice correlated with the intense polymorphonuclear and mononuclear leucocyte inflammatory infiltrate in the CNS.  (+info)

Stimulation of dengue virus replication in cultured Aedes albopictus (C6/36) mosquito cells by the antifungal imidazoles ketoconazole and miconazole. (4/42)

Replication of dengue type 3 virus in Aedes albopictus C6/36 cells was enhanced more than 50-fold by addition of the antifungal imidazole derivative ketoconazole within the first 4 h of infection. The stimulatory effect was reflected in the yield of infectious virus and in levels of viral RNA and protein synthesis. Enhanced yields were observed also for other flaviviruses, including dengue type 2 virus and Murray Valley encephalitis virus. Increased yields of dengue type 3 virus were not observed in African green monkey kidney (Vero) cells, human monocytic (U-937) cells, or cells of the mosquito Toxorhynchites amboinensis (TRA-171).  (+info)

Substitutions at the putative receptor-binding site of an encephalitic flavivirus alter virulence and host cell tropism and reveal a role for glycosaminoglycans in entry. (5/42)

The flavivirus receptor-binding domain has been putatively assigned to a hydrophilic region (FG loop) in the envelope (E) protein. In some flaviviruses this domain harbors the integrin-binding motif Arg-Gly-Asp (RGD). One of us has shown earlier that host cell adaptation of Murray Valley encephalitis virus (MVE) can result in the selection of attenuated variants altered at E protein residue Asp(390), which is part of an RGD motif. Here, a full-length, infectious cDNA clone of MVE was constructed and employed to systematically investigate the impact of single amino acid changes at Asp(390) on cell tropism, virus entry, and virulence. Each of 10 different E protein 390 mutants was viable. Three mutants (Gly(390), Ala(390), and His(390)) showed pronounced differences from an infectious clone-derived control virus in growth in mammalian and mosquito cells. The altered cell tropism correlated with (i) a difference in entry kinetics, (ii) an increased dependence on glycosaminoglycans (determined by inhibition of virus infectivity by heparin) for attachment of the three mutants to different mammalian cells, and (iii) the loss of virulence in mice. These results confirm a functional role of the FG loop in the flavivirus E protein in virus entry and suggest that encephalitic flaviviruses can enter cells via attachment to glycosaminoglycans. However, it appears that additional cell surface molecules are also used as receptors by natural isolates of MVE and that the increased dependence on glycosaminoglycans for entry results in the loss of neuroinvasiveness.  (+info)

Innate resistance to flavivirus infection in mice controlled by Flv is nitric oxide-independent. (6/42)

Innate resistance to flaviviruses in mice is active in the brain where it restricts virus replication. This resistance is controlled by a single genetic locus, FLV, located on mouse chromosome 5 near the locus encoding the neuronal form of nitric oxide synthase (Nos1). Since nitric oxide (NO) has been implicated in antiviral activity, its involvement in natural resistance to flaviviruses has been hypothesized. Here we present data on NO production before and during flavivirus infection in both brain tissue and peritoneal macrophages from two flavivirus-resistant (FLV(r)) and one congenic susceptible (FLV(s)) mouse strains. This study provides evidence that NO is not involved in the expression of flavivirus resistance controlled by FLV since: (a) there is no difference in brain tissue NO levels between susceptible and resistant mice, and (b) lipopolysaccharide-induced NO does not abrogate the difference in flavivirus replication in peritoneal macrophages from susceptible and resistant mice.  (+info)

Antiviral cytotoxic T cells cross-reactively recognize disparate peptide determinants from related viruses but ignore more similar self- and foreign determinants. (7/42)

We have investigated the reactivities of cytotoxic T (Tc) cells against the two immunodominant, H-2K(k)-restricted determinants from the FLAVIVIRUS: Murray Valley encephalitis virus (MVE), MVE(1785) (REHSGNEI) and MVE(1971) (DEGEGRVI). The respective Tc cell populations cross-reactively lysed target cells pulsed with determinants from the MVE(1785)- and MVE(1971)-corresponding positions of six other flaviviruses, despite low sequence homology in some cases. Notably, anti-MVE(1785) Tc cells recognized a determinant (TDGEERVI) that shares with the determinant used for stimulation only the carboxyl-terminal amino acid residue, one of two H-2K(k) anchor residues. These reactivity patterns were also observed in peptide-dependent IFN-gamma production and the requirements for in vitro restimulation of memory Tc cells. However, the broad cross-reactivity appeared to be limited to flavivirus-derived determinants, as none of a range of determinants from endogenous mouse-derived sequences, similar to the MVE-determinants, were recognized. Neither were cells infected with a number of unrelated viruses recognized. These results raise the paradox that virus-immune Tc cell responses, which are mostly directed against only a few "immunodominant" viral determinants, are remarkably peptide cross-reactive.  (+info)

Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. (8/42)

Molecular determinants of virulence in flaviviruses cluster in two regions on the three-dimensional structure of the envelope (E) protein; the base of domain II, believed to serve as a hinge during pH-dependent conformational change in the endosome, and the lateral face of domain III, which contains an integrin-binding motif Arg-Gly-Asp (RGD) in mosquito-borne flaviviruses and is believed to form the receptor-binding site of the protein. In an effort to better understand the nature of attenuation caused by mutations in these two regions, a full-length infectious cDNA clone of Murray Valley encephalitis virus prototype strain 1-51 (MVE-1-51) was employed to produce a panel of site-directed mutants with substitutions at amino acid positions 277 (E-277; hinge region) or 390 (E-390; RGD motif). Viruses with mutations at E-277 (Ser-->Ile, Ser-->Asn, Ser-->Val, and Ser-->Pro) showed various levels of in vitro and in vivo attenuation dependent on the level of hydrophobicity of the substituted amino acid. Altered hemagglutination activity observed for these viruses suggests that mutations in the hinge region may indirectly disrupt the receptor-ligand interaction, possibly by causing premature release of the virion from the endosomal membrane prior to fusion. Similarly, viruses with mutations at E-390 (Asp-->Asn, Asp-->Glu, and Asp-->Tyr) were also attenuated in vitro and in vivo; however, the absorption and penetration rates of these viruses were similar to those of wild-type virus. This, coupled with the fact that E-390 mutant viruses were only moderately inhibited by soluble heparin, suggests that RGD-dependent integrin binding is not essential for entry of MVE and that multiple and/or alternate receptors may be involved in cell entry.  (+info)

TY - JOUR. T1 - Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. AU - Dalgarno, Lynn. AU - Trent, Dennis W.. AU - Strauss, James H.. AU - Rice, Charles M.. PY - 1986/2/5. Y1 - 1986/2/5. N2 - The sequence of 5400 bases corresponding to the 5′-terminal half of the Murray Valley encephalitis virus genome has been determined. The genome contains a 5′ non-coding region of about 97 nucleotides, followed by a single continuous open reading frame that encodes the structural proteins followed by the non-structural proteins. Amino acid sequence homology between the Murray Valley encephalitis and yellow fever (Rice et al., 1985) polyproteins is 42% over the region sequenced. The start points of the various Murray Valley encephalitis virus-coded proteins have been assigned on the basis of this homology and a consistent set of potential proteolytic cleavage sites identified, ...
Looking for Murray Valley encephalitis? Find out information about Murray Valley encephalitis. An acute inflammation of the brain and spinal cord caused by a virus; confined to Australia and New Guinea. Also known as Australian X disease. Explanation of Murray Valley encephalitis
Genetic and phenotypic variation of genotype 1 (G1) and genotype 2 (G2) Murray valley encephalitis virus (MVEV) were characterised. G2 viruses were a minority, had lower levels of genetic diversity and an attenuated phenotype in the mouse model of MVE. G1 isolates were abundant with higher levels of genetic diversity and a virulent phenotype. The restricted evolution of MVEV was due to multiplication in mosquito cells. An RT-qPCR assay detecting all MVEV genotypes was developed.. ...
TY - JOUR. T1 - Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses. AU - Mackenzie, J.S.. AU - Lindsay, M.D.. AU - Broom, A.K.. PY - 2000. Y1 - 2000. M3 - Review article. VL - 21. SP - 20. EP - 24. JO - Microbiology Australia. JF - Microbiology Australia. SN - 1324-4272. IS - 2. ER - ...
Objective: To assess evidence of recent and past exposure to Murray Valley encephalitis virus (MVEV) and West Nile clade Kunjin virus (KUNV) in residents of the Murray Valley, Victoria, during a period of demonstrated activity of both viruses in early 2011. Methods: A cross-sectional serosurvey using two convenience samples: stored serum specimens from a diagnostic laboratory in Mildura and blood donors from the Murray Valley region. Specimens were collected between April and July 2011. The main outcome measure was total antibody (IgM and IgG) reactivity against MVEV and KUNV measured using an enzyme immunoassay and defined as inhibiting binding of monoclonal antibodies by ,50%, when compared to negative controls. Evidence of recent exposure was measured by the presence of MVEV and KUNV IgM detected by immunofluorescence. Results: Of 1,115 specimens, 24 (2.2%,95% CI 1.3-3.0%) were positive for MVEV total antibody, and all were negative for MVEV IgM. Of 1,116 specimens, 34 (3.1%, 95% CI 2.0-4.0%) ...
Summary A Papuan native boy aged about 14 years died of acute encephalitis at Port Moresby in May 1956. A virus, isolated from the brain, has been identified as a strain of Murray Valley encephalitis virus and designated MVE-1-56.
We undertook annual surveys of flavivirus virus activity in the community of Billiluna of Western Australia in the southeast Kimberley region between 1989 and 2001. Culex annulirostris was the dominant mosquito species, particularly in years of above average rains and flooding. Murray Valley encephalitis (MVE) virus was isolated in 8 of the 13 years of the study from seven mosquito species, but more than 90% of the isolates were from Cx. annulirostris. The results suggest that MVE virus is epizootic in the region, with activity only apparent in years with average or above average rainfall and increased numbers of Cx. annulirostris. High levels of MVE virus activity and associated human cases were detected only once (in 1993) during the survey period. Activity of MVE virus could only be partially correlated with wet season rainfall and flooding, suggesting that a number of other factors must also be considered to accurately predict MVE virus activity at such communities.
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A new insect-specific flavivirus from Northern Australia suppresses replication of West Nile Virus and Murray Valley Encephalitis Virus in co-infected mosquito cells. Hobson-Peters, Jody, Yam, Alice Wei Yee, Lu, Jennifer Wei Fei, Setoh, Yin Xiang, May, Fiona J., Kurucz, Nina, Walsh, Susan, Prow, Natalie A., Davis, Steven S., Weir, Richard, Melville, Lorna, Hunt, Neville, Webb, Richard I., Blitvich, Bradley J., Whelan, Peter and Hall, Roy A. (2013). A new insect-specific flavivirus from Northern Australia suppresses replication of West Nile Virus and Murray Valley Encephalitis Virus in co-infected mosquito cells. PLoS One, 8 (2) e56534, e56534. doi: 10.1371/journal.pone.0056534. ...
Unspecified hepatitis include cases in whom the duration of infection could not be determined. † In the Northern Territory and Queensland, includes incident hepatitis cases. ‡ Notified as foodborne disease or gastroenteritis in an institution in New South Wales. § Infection with Shiga-like toxin/verotoxin-producing Escherichia coli (SLTEC/VTEC). ,, Includes Chlamydia trachomatis identified from cervical, rectal, urine, urethral, throat and eye samples, except for South Australia which reports only genital tract specimens, the Northern Territory which excludes ocular specimens, and Western Australia which excludes ocular and perinatal infections. ¶ Laboratory confirmed influenza is not a notifiable disease in South Australia but reports are forwarded to NNDSS. ** Flavivirus (NEC) replaces Arbovirus (NEC) from 1 January 2004. †† In the Australian Capital Territory, Murray Valley encephalitis virus and Kunjin virus are combined under Murray Valley encephalitis virus. ‡‡ In the ...
Lifetime Student in school of Hard Knocks.Born in Troy NY home of UncleSam,FALLOUT Capital of the Nation(googleThe Troy Incident)other places I called home; Tucson & Bullhead City, Az., Seattle,Wa.,Taos,Ojo Caliente &Santa Fe,NM, LasVegas,Searchlight,Goodsprings,Jean,& Laughlin,NV.,San Francisco, Ca.,Portland,Or.,just 2 name a few. Places I have worked are bars, horse & dog tracks and casinos, and, later in life,law firms & with lawyers. Now in retirement,I stay home & mind my little mini-farm. In my spare time I pretty much live vicariously through the wonders of the www. I guess you could say (ala Eddie Rabitt) that I am - bloggin my life away,....lookin for & workin towards a better day, ohhh yeah. But however you look at it, there aint no gettin around it, Im jus an ole x-hippy-chick, struggling ever onward through the fog of life,....still here, still standin,..still laughing, after all these crazy years, and whats more amazing yet, still with at least some functioning brain ...
These Pathogen Safety Data Sheets, regulated under Workplace Hazardous Materials Information System (WHMIS) legislation, are produced for personnel working in the life sciences as quick safety reference material relating to infectious micro-organisms.
Fact sheets on Barmah Forest virus infection, chikungungya, dengue, kunjin virus, Japanese encephalitis virus, malaria, Murray Valley encephalitis virus, Ross River virus infection, and West Nile virus are available from States and Territories.
Andy Murray and the other three top British tennis players will play at the Rio Olympics.. Murray, who will try to become the first repeat Olympic mens singles champion in Rio, is joined on the British Olympic team by brother Jamie Murray and the top two British female singles players, Johanna Konta and Heather Watson.. Murray won the then-biggest title of his career at the London Olympics on the lawns of Wimbledon, beating Novak Djokovic in the semifinals and Roger Federer in the final, one month after his heartbreaking loss to Federer in the Wimbledon final.. Since, Murray won his first two Grand Slam singles titles and vaulted to No. 2 in the world behind Djokovic, whom he lost to in this years Australian Open and French Open finals.. Murray returns for his third Games, after debuting at Beijing 2008 at age 21. He is set to play doubles at a third straight Olympics with his brother, looking to better first- and second-round exits at the last two Olympics.. Jamie Murray, ranked No. 2 in the ...
Murray, on rhythm guitar and backing vocals, became a founding member of the Warumpi Band alongside Aboriginal members, Sammy Jabanangka Butcher on guitar and bass guitar; his brother, Gordon Jabanangka Butcher on drums; and George Rurrambu (born Kumanjayi Rurrambu II Burrarrawanga aka George Djilaynga) on lead vocals and didgeridoo.[8][9][10] The Warumpi Band were pioneers of Aboriginal rock music and with Murray as a member they released two albums, Big Name, No Blankets (April 1985) and Go Bush! (April 1987).[8] They toured widely, including the Blackfella/Whitefella Tour through outback Australia with Midnight Oil in 1986.[8][11] The tour is named for Warumpi Bands 1985 single, Blackfella/Whitefella, which was co-written by Murray and Djilaynga.[12] Another single by the group, My Island Home (1987), was written entirely by Murray.[1][2] By the end of 1988 Murray had left the group and relocated to Sydney.[2] Murray launched his solo career and by 2014 had released eight studio albums, ...
Dr. Conrad Murray, Michael Jackson's personal physician and the focus of the investigation into the King of Pop's death, has made his first public statements since Jackson's death on June 25th, thanking his supporters in a video posted onto YouTube today. While Murray doesn't apologize or mention Jackson's name in the video, he does say that he can't return phone calls or e-mail because of all that's going on. With reports that Murray faces the possibility of manslaughter charges in Jackson's death, Murray states, I have done all I could. I told the truth, and I have faith the truth will prevail.. Look back at Michael Jackson's life, in photos.. According to TMZ, the video was filmed last Wednesday, August 12th, the day after investigators raided a Las Vegas pharmacy where Murray allegedly purchased the Propofol he administered to Jackson. The day after the video was recorded, the Los Angeles Times reported that Murray left Jackson unsupervised ...
The Department of Health is urging people living and holidaying in WAs north to take extra care against mosquito bites due to the increased risk of mosquito-borne viruses in the Kimberley and Pilbara regions.. Director of Environmental Health Jim Dodds said that the Departments surveillance program (undertaken by The University of Western Australia) had detected activity of the rare, but potentially fatal, Murray Valley Encephalitis (MVE) virus in the Pilbara region for the first time this wet season.. MVE disease is carried by mosquitoes and, although rare, it can be fatal or cause severe symptoms, so it is important that people take precautions to avoid mosquito bites, particularly following the widespread rains in the Pilbara over the past week, he said.. Initial symptoms of MVE include fever, drowsiness, headache, stiff neck, nausea and dizziness and people experiencing these symptoms should seek medical advice quickly.. In severe cases, people may experience fits, lapse into a coma, ...
media icon Text alternative:. World Mosquito Day. Mosquitos cause more death & disease than any other animal on the planet.. Malaria, Dengue, Yellow Fever, Japanese Encephalitis, West Nile Chickungunya, Kunjin Jamestown Canyon Virus, Zika, Venezuelan Equine Encephalitis, St Loius Encephalitis, Pogostra Disease, Ross River Virus, Lymphatic Filariasis, Eastern Equine Encephalitis, Murray Valley Encephalitis, Rift Valley Fever, Lacrosse Encephalitis.. And the list goes on.. CDC Works Worldwide to Prevent and Eliminate Deadly Diseases Spread By Mosquitoes.. To Lear More, Visit www.cdc.gov/globalhealth/. ...
Diagnostic tests for ZIKV infection include PCR tests on acute-phase serum samples, which detect viral RNA, and other tests to detect specific antibody against ZIKV in serum. An ELISA has been developed at the Arboviral Diagnostic and Reference Laboratory of the Centers for Disease Control and Prevention (Ft. Collins, CO, USA) to detect immunoglobulin (Ig) M to ZIKV (1). In the samples from Yap Island, cross-reactive results in sera from convalescent-phase patients occurred more frequently among patients with evidence of previous flavivirus infections than among those with apparent primary ZIKV infections (1,2). Cross-reactivity was more frequently noted with dengue virus than with yellow fever, Japanese encephalitis, Murray Valley encephalitis, or West Nile viruses, but there were too few samples tested to derive robust estimates of the sensitivity and specificity of the ELISA. IgM was detectable as early as 3 days after onset of illness in some persons; 1 person with evidence of previous ...
This article published in Communicable Diseases Intelligence Volume 25, No 2, April 2001 contains the bi-monthly report on the Australian sentinel chicken surveillance programme to detect early signs of Murray Valley encephalitis and Kunjin virus
Murray Grey is a breed of Australian polled beef cattle that was developed in the upper Murray River valley on the New South Wales /Victorian border. They have evolved into a versatile breed that does well in a wide range of environments and produces top quality carcasses. The Murray Grey breed was developed from an initial chance mating of a black Aberdeen Angus bull and a roan Shorthorn cow in 1905 during the Federation drought. The resulting thirteen dun-grey calves from these matings were kept as curiosities and then bred on the Thologolong property along the Murray River in New South Wales by Peter and Ena Sutherland. These unusually coloured cattle grew quickly, were good converters of feed and produced quality carcases. Local cattlemen soon became interested in the greys and began breeding them. The first larger-scale commercial herds were established in the 1940s. In the 1960s several grey cattle breeders were selling them as a commercial enterprise and the Murray Grey Beef Cattle ...
Download The Original Black Elite: Daniel Murray and the Story of a Forgotten Era or Read The Original Black Elite: Daniel Murray and the Story of a Forgotten Era online books in PDF, EPUB and Mobi Format. Click Download or Read Online Button to get Access The Original Black Elite: Daniel Murray and the Story of a Forgotten Era ebook. Please Note: There is a membership site you can get UNLIMITED BOOKS, ALL IN ONE PLACE. FREE TO TRY FOR 30 DAYS. In order to Download The Original Black Elite: Daniel Murray and the Story of a Forgotten Era or Read The Original Black Elite: Daniel Murray and the Story of a Forgotten Era book, you need to create an account.. Category: ...
Find Anxiety Therapists, Psychologists and Anxiety Counseling in Kips Bay and Murray Hill New York 10016, get help for Anxiety in Kips Bay and Murray Hill New York 10016, get help with Fears in Kips Bay and Murray Hill New York 10016, get help with Phobia in Kips Bay and Murray Hill New York 10016.
The State Government has announced it will contribute $400,000 towards treatment for a police officer struck down by Murray Valley Encephalitis.
Cherry Murray, formerly a professor of technology, public policy and physics at Harvard University, has been confirmed as director of the Energy Departments Office of Science.. Murray will be responsible for research initiatives in advanced scientific computing, high energy physics, nuclear physics and biological, environmental, fusion energy and basic energy sciences, DOE said Friday.. DOE Secretary Ernest Moniz said Murray brings her experience in academia and industry and in the fields of engineering and applied sciences.. She previously served as dean of the school of engineering and applied sciences at Harvard University after she held the positions of principal associate director for science and technology and deputy director for science and technology at Lawrence Livermore National Laboratory.. Murray also worked for Bell Laboratories and Lucent Technologies.. She is a member of the National Academy of Sciences, American Academy of Arts and Sciences and the National Academy of ...
The review cited research we published this month, which concluded it was impossible to achieve the basin plan target to keep the Murray Mouth open 95% of the time.. This is because Murray Darling Basin Authority modelling did not factor in the power of the Southern Ocean to move sand into the Murray Mouth, which is now choked. Dredging will be required most of the time to keep the Murray Mouth open and maintain the ecology of the Coorong.. The Coorong and Lakes Alexandrina and Albert are a wetland of international importance under the Ramsar Convention.. The review found removing the barrages would significantly change the freshwater character of the site, which we have an international obligation to maintain for the sake of waterbirds, fisheries and threatened species.. This is becoming harder during periods when freshwater inflows are scarce. In the Millennium Drought for example, lake levels fell exposing highly acidic mudflats. In other areas, the waters became more salty.. After the basin ...
Cornwall Ontario - At 4pm this afternoon Dr. Conrad Murray arrived at an L.A county courthouse to turn himself in on charges related to Michael Jacksons death. It is expected that Murray will be charged with involuntary manslaughter, this comes seven months after the death of M.J.. Since the King of Pops untimely death last year, fans from around the world have been scrambling to buy all of his records and memorabilia they can find. Between the this is it campaign and sales from previous records, Jacksons estate might be able to get back into the black.. Murray, Jacksons personal physician who was in charge of keeping him healthy throughout his last tour, has been a person of suspect from day one. The publics concern with Murrays involvement with Jacksons death increased when the pop stars toxicology report was released. It stated that Jackson died of a cardiac arrest due to an overdose of Propofol.. Propofol is an anesthetic that is administered through an I.V drip. Murray could have a ...
Murray told her he had given the singer small doses of a sedative, lorazepam, she said. Flanagan suggested that Murray may have left out propofol because he believed it had worn off earlier in the day and was not the cause of his cardiac arrest.. Cooper agreed the amount Murray later told police he had given Jackson -- 25 miligrams -- was small. She said she used more than twice that amount to sedate patients and questioned whether it would have knocked the singer out at all.. I wouldnt expect that to produce any levels of sedation, she said.. If it did, she added, [In] seven to 10 minutes, it would probably be worn off.. A prosecutor questioned Cooper briefly about her dealings with the singers children, whom she went to see after she had pronounced Jackson dead the second time.. They were crying. They were fairly hysterical, she recalled.. Murray, 58, is charged with involuntary manslaughter.. He contends Jackson self-administered a lethal amount of propofol when he was out of the ...
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blogger- Conrad Murray was a physician who assumed Michael Jacksons care. He, therefore, had a legal duty to care for Michael Jackson. His failure to perform his legal duty is the direct cause of Michael Jacksons death which would not have happened if it wasnt for Conrad Murrays deviations from the standard of care. A reasonable doctor in his place would have known that the dangerous setting Conrad Murray treated Mr. Jackson was a recipe for disaster. We had doctor after doctor testify that they would NEVER do what Conrad Murray did. Even the defense witness, Dr White testified that no amount of money could pursue him to do what Conrad Murray did. Ed Chernoff said in his opening well Michael Jackson received Propofol for two months and he didnt die. See, it was not a dangerous circumstance. Mr. Chernoffs argument is as absurd as someone who killed while playing Russian roulette saying well when I pulled the trigger for the first 4 times, there was no danger. Propofol…to treat ...
Murray family (per. 1768-1967), publishers, was an important book trade dynasty famous for publishing the works of Byron, the Quarterly Review, and Darwins Origin of Species.. The house of Murray was established in the late eighteenth century by John Murray [formerly McMurray] [John [i] Murray]... ...
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Murray was born in Aberdeen and after attending Roger Gordons College began his career as an insurance broker with Norwich Union in Dar es Salaam in 1960, moving in 1964 to Nairobi where he joined J.H. Minets. He lived in Kenya until 1984 when he returned to Scotland to run his own business as Murray Agencies. During his twenty year residence in Kenya, Murray was an ardent supporter of Nondescripts RFC and for several years was Chairman of the East African Motor Sports Club. He drove in several East African Safari rallies and was lucky to survive a serious accident in 1969 when the steering wheel became detached on a high speed section of the route. The car ended up in a ditch with Murray waving the wheel above his head, much to the consternation his co-driver. Fortunately, the accident occurred close to a bar - and bars were not common in the Kenyan bush.. ...
Murray Drug Corp. - Get up-to-date information on Murray Drug Corp. side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Murray Drug Corp.
Newton, Jan; Murray, James W (2003): Particulate carbon, nitrogen and chlorophyll pigments of sediment trap TT007_3-Murray_trap. PANGAEA, https://doi.org/10.1594/PANGAEA.125563
DENVER (AP) - Denver Nuggets point guard Jamal Murray was ruled out for the rest of the game against the Charlotte Hornets after leaving late in the first half after rolling his left ankle.. Murray tried to contest a 3-point shot by Terry Rozier on Wednesday night and appeared to land on Roziers foot. Murray instantly grabbed at his ankle as play was stopped. He was helped off the floor by teammates and then placed in a wheelchair once he left the court.. ...
The trial of Conrad Murray will begin March 24. Lawyers for Michael Jacksons doctor have found a defense to avoid a conviction for involuntary manslaughter. According to TMZ, Dr. Conrad Murray will declare that the death of the King of Pop is not due to propofol, a powerful anesthetic, but to the stars weakened state. Add to that the extreme weakness and fatigue the artist was facing in the course of promoting the This Is It tour, which forced him to repeat for many hours. Dr. Murrays statements should be supported by witnesses who attended the rehearsals of Michael Jackson.. Apart from the stars poor health, Dr. Conrad Murray will argue that Jackson himself administered propofol to himself during his absence. This trial will in any case draw much attention and excite millions of fans around the world who will also attend various hearings. ...
Application packet. Applicants with any 4-year Undergraduate degree can apply for the program. Completed applications packets from domestic students must be received by December 1st for Spring admission, and by June 1st for Fall admissions. Applications from International students must be received by October 1st for Spring admission, and April 1st for Fall admissions. The complete application packet includes:. 1. Official Undergraduate transcript. 2. Official GRE (or GMAT) score report. Murray State Universitys Institutional code is 1494. If you are already at Murray State, the GRE may be taken at our Counseling and Testing Center (270-809-6851). Please call and schedule at least three weeks in advance of the date you wish to take the test.. 3. A current résumé and. 4. Additionally, international students whose native language is not English must submit evidence of English proficiency; we accept official TOEFL or IELTS scores as evidence. (Institution code: 1494). See Proficiency requirements ...
Today, 11/29/11, the MJGlobal family witnessed the sentencing of Conrad Murray. After a brief synopsis of the events, case and trial, Walgren asked Judge Pastor to consider the documentary that Murray filmed and he did. Walgren said that Murray demonstrated that he takes no responsibility for his own actions and states exact words from his own…
With opening statements in the grand Jacksons v AEG Live court case due to begin later today, the doctor convicted for causing Michael Jacksons death through negligence, Conrad Murray, has given yet another interview from jail. And again he has declared his innocence, announcing that he is determined to win his medical licence back.. As previously reported, the Jackson family is claiming that AEG Live, promoters of Michael Jacksons ill-fated This Is It show, should be held liable for the late king of pops death, because it hired Murray. AEG counters that while it paid Murrays bills, Jackson himself recruited the medic, and managed him on a day-to-day basis.. That Murrays negligence caused Jacksons demise will be taken as read in the civil case, but the former doctor is trying to appeal his 2011 conviction. And in a new interview with Americas Today Show, Murray said: I hope the court will see that an injustice has occurred on this occasion. If that is the case, I will have my [medical] ...
Mr Murray Stewart does not hold a share or financial interest in this hospital, another Nuffield Health hospital or the company.. Mr Murray Stewart does not have a share or financial interest in equipment used at this hospital or another Nuffield Health hospital.. Mr Murray Stewart does not hold any paid advisory role(s) at this hospital or on behalf of Nuffield Health.. ...
Murray is accused of administering the fatal dose of the drug which claimed Jacksons life on 25 June, 2009, and he is currently on trial for involuntary manslaughter in Los Angeles Superior Court.. Dr. Richelle Cooper first took to the stand on Friday and told how Murray had insisted Jackson was just dehydrated when he was admitted to her care at Ronald Reagan UCLA Medical Center. She said Jackson did not have a pulse when he arrived at the hospital.. She resumed her testimony on Monday, when she confirmed to the court that Murray had made no mention of providing Propofol to his famous patient - as she attempted to resuscitate the star - and only revealed he had administered the sedative lorazepam, sending the singer into cardiac arrest.. Cooper also testified that she had given paramedics on the scene at Jacksons rented California home permission to pronounce the superstar dead, although the singer was then admitted to hospital on Murrays insistence in a desperate bid to try and ...
The defense accused prosecutors of playing on the emotions of jurors by repeatedly showing them a photo of Jacksons children, a device Chernoff said was designed to paint Jackson as a victim. A prosecutor told jurors Thursday that the testimony of a renowned anesthesiologist in Murrays defense was junk science.. The harsh rebuke of the testimony of Dr. Paul White, a leading expert on the surgical anesthetic propofol, came near the conclusion of the prosecutions closing argument.. White, who was among the first scientists in the U.S. to study the drug, testified over four days in Murrays defense and said Jackson probably injected himself with the drug, causing his own death.. RELATED:. Defense calls Conrad Murray a victim as case goes to jury. Conrad Murrays defense employed junk science, D.A. says. Conrad Murray lied to police about Jacksons death, D.A. says. -- Victoria Kim and Harriet Ryan at L.A. County Superior Court. Photo: Conrad Murray, center, stands with defense attorneys J. ...
James Murray, Producer: Impractical Jokers. James Murray was born on May 1, 1976 in Staten Island, New York City, New York, USA as James Stephen Murray. He is a producer and actor, known for Impractical Jokers (2011), Awakened (2018) and Impractical Jokers: After Party (2017). He was previously married to Jenna Vulcano.
Health,Fresno CA (PRWEB) June 11 2013 SmileCare is proud to welcome oral surgeon Matt Murray DDS MD to its team of dental specialists and general dentists. Dr. Murray has traveled around the world to help fix smiles. His services include bone grafting cosmetic surgery dental implants dentoalveolar surgery extractions pre-prosthetic surgery ridge augmentat,Oral,Surgeon,Matt,Murray,Joins,SmileCare,in,Bakersfield,,Fresno,and,Modesto,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Penguins goaltender Murray out tending to personal matter. - posted in General Discussion: Penguins goaltender Murray out tending to personal matter. PITTSBURGH (AP) - Pittsburgh Penguins goaltender Matt Murray is in Canada with his family to tend to a personal matter and will be away from the team... India limits visitors to save Taj Mahal. Millions of mostly Indian tourists visit the Taj Mahal every online year and their numbers are increasing as domestic travel becomes easier. Experts s...
Last month marked the seventh annual Joseph Murray Visiting Professorship in Transplantation-the first such lecture since Murrays passing last year.. Dr. Murray was always very clear that the success of transplantation was based not only on his doing, but on the multidisciplinary approach, said Stefan Tullius, MD, chief of Transplant Surgery, in welcoming guests to the event. What made Dr. Murray so special was his curiosity, his wonderful optimism and his gentle persistence. We now must try to move transplantation and this lecture forward.. True to Murrays focus on multidisciplinary collaboration, the lecture itself is made possible by a partnership among Transplant Surgery, Renal Medicine, Infectious Disease and the Center for Surgery and Public Health at BWH.. Addressing HIV and Transplant in South Africa. This year, Elmi Muller, MD, head of Transplantation Services at Groote Schuur Hospital in Cape Town, South Africa, presented.. I feel so privileged today to give this talk in memory ...
Murray Grey: Breed of Australian beef cattle first bred in 1905 in the Murray River valley on the border between New South Wales and Victoria. Its characteristic colour is grey, and the breed...
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NSW Health is warning parents and school communities about a range of health risks associated with mosquito bites.. There has been a significant increase in the numbers of mosquitoes in some parts of NSW following recent heavy rainfall and flooding.. Mosquitoes can transmit a number of viral infections, including Ross River virus and Barmah Forest virus, and a large number of these infections have been reported in 2011.. A rarer but more serious mosquito-borne infection called Murray Valley encephalitis has also been detected in western NSW.. School students who live in western NSW, or who plan to travel west of the Great Dividing Range on school camps or excursions, should take particular care to prevent mosquito bites.. Mosquitoes are most active around dusk, in the first few hours of the evening and again at dawn.. Rivers, creeks, wetlands and recently-flooded land allows mosquitoes to breed. People living near or visiting these areas need to be especially careful.. Prevent mosquito ...
The death of a Canadian tourist from a mosquito-borne disease is the latest in a string of cases around Australia.. The Northern Territory Health Department yesterday reported the death of a Canadian woman who visited the Top End and central Australia earlier this month.. She contracted Murray Valley encephalitis, a disease which can cause severe headaches, drowsiness, seizures and death.. In March, a person in Victoria died from the disease and South Australia has recorded its first locally-contracted cases since the 1970s.. A 27-year-old South Australian man also died.. The NSW Health Department has reported finding the disease in sentinel chickens in the west of the state.. The Territory Health Department says there is no specific treatment for the disease and people should take steps to avoid getting bitten by mosquitoes. ...
Andrew Murray (1813-1880), journalist, was born on 16 May 1813 in Kirkbean, Kirkcudbrightshire, Scotland, son of Rev. William Murray and his wife Marianne, née Bridges. Educated in Glasgow and at its university where in 1836 with a work on Oliver Cromwell he won the Peel Clubs first prize essay, he arrived at Port Adelaide in January 1839. He formed the drapery business of Murray, Greig & Co., but it failed in November 1842. He became editor of the South(ern) Australian early in 1843 and its proprietor from 31 October 1844 to 19 August 1851. Opponents called it a tame rag … not worth the postage, but it was noted for mild editorials, general support of the government and catering for the wealthy pastoralists who disliked the South Australian Register for favouring small farmers. From 1845 Murray had also acted as government printer and at his office in Rundle Street issued many periodicals, the weekly government gazette and annual South Australian almanacs and directories. In January 1852 ...
Recent five years (student collaborators are underlined):. (1) Second International Conference on Game Jams, Hackathons and Game Creation [JM1] Events [San Francisco, CA; February 2017] Brain Jam - STEAM learning through Neuroscience-themed game development, Ian Pollock, James Murray and Beth Yeager (paper & oral presentation). (2) Society for Integrative and Comparative Biology [New Orleans, LA; January 2017]. Ciliary-driven currents may enhance olfactory sampling in nudibranch gastropods, Ames AM, Murray JA (Poster presentation). (3) Society for Neuroscience [San Diego; November 2016]. Game jam with brain bee: STEAM learning through neuroscience-themed game development, Murray JA, Pollock I, Leal D, Bobino C, Yeager E, Yao TJ, Hain J, Zib K (Poster presentation). (4) Society for Integrative and Comparative Biology [Portland, OR; January 2016]. Elucidating the neural circuit involved in chemotaxis in Tritonia tetraquetra, Zacarias S, Murray JA (Poster presentation). (5) Society for Integrative ...
http://groups.yahoo.com/group/aspartameNM/message/1126 same amount of methanol (source of formaldehyde, formic acid) from aspartame as from dark wines and liquors: Utz: Murray 2004.10.19 rmforall From: Jeffrey P Utz ,jeffutz at juno.com, To: ,Quackbusters at yahoogroups.com, Subject: Re: [Quackbusters] Aspartame -- Sweet Or Sour? Thea Jourdan, The London Daily Mail 2004.10.04: Murray 2004.10.18 rmforall Date: Tuesday, October 19, 2004 6:21 AM Funny, you anti aspartame folks claim the ethanol in fruit is an antidote for the methanol in fruit. Funny, how in liquor, it doesnt do this. Could you please provide references for the 11% methanol in dark wines and liquors, as well as how these cause headaches? Jeff On Mon, 18 Oct 2004 21:30:00 -0600 Rich Murray ,rmforall at comcast.net, writes: http://groups.yahoo.com/group/aspartameNM/message/1125 Aspartame -- Sweet Or Sour? Thea Jourdan, The London Daily Mail 2004.10.04: Murray 2004.10.18 rmforall [ Comments by Rich Murray are in square brackets. ...
http://groups.yahoo.com/group/aspartameNM/message/1165 short review: research on aspartame (methanol, formaldehyde, formic acid): Murray 2005.04.09 Rich Murray, MA Room For All rmforall at comcast.net 505-501-2298 1943 Otowi Road Santa Fe, New Mexico 87505 USA http://groups.yahoo.com/group/aspartameNM/messages group with 180 members, 1,165 posts in a public, searchable archive http://groups.yahoo.com/group/aspartameNM/message/1071 research on aspartame (methanol, formaldehyde, formic acid) toxicity: Murray 2004.04.29 rmforall http://groups.yahoo.com/group/aspartameNM/message/1143 methanol (formaldehyde, formic acid) disposition: Bouchard M et al, full plain text, 2001: substantial sources are degradation of fruit pectins, liquors, aspartame, smoke: Murray 2005.04.02 rmforall Aspartame (NutraSweet, Equal, Canderel, E951), after eight years of controversy, was suddenly and capriciously approved by a new FDA commissioner, Arthur Hull Hayes, Jr, just appointed by President Reagan, a pharmacologist ...
30 November 2019. Time for cool heads, not posturing over Murray. South Australias peak environment body has strongly backed SA Environment Minister David Speirs as he rejects the call to remove barrages at the lower end of the Murray.. The Murray Darling Basin Plan remains the best shot for keeping the River alive as we struggle with declining rainfall across the Basin, said Craig Wilkins, Chief Executive of Conservation SA.. It is deeply disappointing that hotheads from NSW are threatening to blow up the Plan. When SA was suffering far more than NSW during the Millennium Drought, we stuck at it, and so should they.. We were the first state to put a voluntary cap on water entitlements, and have always been ahead of the game when it comes to efficiency and compliance.. South Australia only receives 7% of the river flow, and we have 7% of the population in the Basin.. Destroying the lower end of the River by reducing the 7% of flows even further is not the solution to NSW woes.. There is ...
By Les Murray The signature quality of a Les Murray poem is anger - a visceral smoldering that freshly lights up the tired old landscape and turns conventional pieties inside out. A lifelong outsider and champion of the underdog, Murray grew up among impoverished farmers in rural Australia, where, as an
Sen. Patty Murray (D., Wash.) said Wednesday she believes a worse idea than going over the fiscal cliff would be to extend the Bush tax rates for wealthy Americans.. What we are all saying is that its not a good idea to go over the fiscal cliff-no one wants to see that happen, it is a bad idea, Murray said, when asked about the dangers of the fiscal cliff.. But a worse idea is to accept a compromise that allows the wealthy Americans to not pay their fair share, she continued, because the result of that will be that middle-class families will pay the entire burden of the challenges that this country faces.. An analysis from the nonpartisan Joint Committee on Taxation indicated the proposed tax increases would amount to $68 billion more tax revenue in 2013 - between 6.5 and 8.5 percent of the projected 2013 shortfall and just 0.18 percent of the total $3.8 trillion projected spending for 2013.. In July, Murray threatened to go over the fiscal cliff should a deal not increase taxes on the ...
That vote is expected to take place in September and the deal could be finalized in October. But for most Marlins fans, just punting Loria out the door is a victory in and of itself. But there are very, very few that could combine all three. He was behind the bench for the Bears in 1980-81 and quickly established himself as one of hockeys great coaches.. Among the National Hockey League executives Murray mentored is Minnesota Wild general manager Chuck Fletcher. When his fellow GMs honored him at their annual March meeting in 2015, nephew Tim Murray and others said they went to get a colonoscopy after learning about Bryans diagnosis. He knows the Xs and Os of the game of hockey really well and I dont think theres anyone who will dispute that. He really loved just the daily interaction with the players, being on the ice, being behind the bench, setting the strategy for the game and how the team would play.. We watch London play Plymouth in the playoffs and (Bryan Murray) watches ...
What are Murray Field Airport (EKA) Taxi Fares to Downtown? | How Much is a Taxi from Murray Field Airport to Downtown? | Murray Field Airport Transfers
Brisbane nanny Sara Zelenak, 21, and Loxton, South Australia, nurse Kirsty Boden, 28, died when the three men ploughed into pedestrians in a white van on the bridge then stabbed evening revellers in the nearby market with 12-inch ceramic knives. ...
Dans le contexte dune grave dégradation environnementale, cet article analyse les discours gouvernementaux et Ngarrindjeri autour de leau et de sa gestion dans le Lower Murray Country (Australie Méridionale). Cet article montre quune gestion de leau aux relents coloniaux dans le bassin Murray-Darling expose la région Lower Murray à une menace écologique sans précédent. Une poétique de lailleurs, tournée vers le futur, paternaliste et intransigeante dans sa langue, est mise en œuvre pour tenter de justifier ces pratiques monolingues qui bâillonnent toute épistémologie alternative. En réponse à cette gestion impérialiste (décrite comme une deuxième vague de dépossession), et soutenus par la reconnaissance grandissante dans le monde du droit des populations indigènes, les propriétaires traditionnels du bassin ont développé le concept de Flux Culturels pour détourner ces discours étouffants et réaffirmer leur droit dêtre entendus au sein des agences gouvernementales
Poet, writer, broadcaster and performer Murray Lachlan Young will be stopping off at Norwich Playhouse on Saturday 27th April as part of his latest national tour. Murrays family-friendly (2.30pm) show, entitled The Mystery of The Raddlesham Mumps, is described as a gothic epic-poem that will delight children and adults alike. Accompanied by music from award-winning jazz instrumentalist Arun Ghosh, Lachlan Young will perform his witty and darkly comic three-act verse in his usual theatrical and irreverent style.. The Mystery of the Raddlesham Mumps reflects Lachlan Youngs passion for sweeping, gothic and absurdly comic childrens poetry. The poem is not just a live theatre show, it has also been developed as a book, a CD, and an interactive Virtual Reality experience. Murray Lachlan Young explains his inspiration; As a child I was read verse by my mother, people like Hilaire Belloc and Edward Lear. At the same time, I was also listening to my parents entire record collection. Everything from ...
Arizona quarterback Kyler Murray sat out most of the first three quarters with an ankle injury and when he finally returned, wasnt able to rally the Cardinals into the playoffs. Murray was hurt on the first possession Sunday and didnt return until early in the fourth quarter, when the Cardinals trailed the Los Angeles Rams 18-7. Thats how the game ended after Murrays first drive ended in a blocked field goal and he wasnt able to get the Cards any closer.
The multidisciplinary team of surgeons at Intermountain Vascular and Vein Clinic - Murray provide the most appropriate care for patients who have diseases of arteries and veins. This collaborative approach brings together the knowledge and expertise of specialists from vascular medicine and surgery. Our caregivers are board certified and fully accredited, and have vast experience in the evaluation, management and care of patients with vein and arterial conditions. Our clinic provides an inviting, comfortable medspa environment where patients receive state-of-the-art treatments to improve their well-being and quality of life.. ...
BOSTON (AP) - Dr. Joseph E. Murray, who performed the worlds first successful kidney transplant and won a Nobel Prize for his pioneering work, has died at age 93. Murray suffered a stroke at
ATS Career Center: Physicians/Surgeons, , Murray, Utah , Interventional Pulmonary - Murray, UT - Intermountain Medical Center at Intermountain Healthcare
Hi Bonnie. In the video scream he has only one seven on his chest. I was thinking about Murray. He said in the documentary that he got entrapped by MJ. MJ told him in the beginning that he wanted Murray to be there if he or his children catched a cold or got the flu. He make it sound like MJ manipulated him. He also said he didnt give MJ something he met him with something. Murray said he asked MJ how he would manage to sleep without propofol after the tour. MJ replied, that is no problem I just need it during the tour. It makes you go hmm. He said he met him with something. But he hadnt been on tour for ages. Murray was quick to give names and blame almost everybody but him self, it also make you go hmmm. Liers are often quick to do just that. The news said that Murray was in total chock when he got the verdict. Doesnt the lawyers prepare their clients for the worst scenario. The lawyers even mentioned in the documentary that they thought they might lose the case. And Murray didnt have a ...
MURRAY, Utah -- Police are investigating a home invasion that happened in Murray Monday morning. Officers said it happened around 10:30 a.m. in a condo at 5572 South Marshwood Lane. After police responded to the home invasion, two of the people staying in the condo were arrested on warrants.
Dr. Murray is professor of global health and social medicine in the Department of Global Health and Social Medicine and associate professor of medicine in the Department of Medicine, Harvard Medical School, and professor of epidemiology at Harvard School of Public Health. Dr. Murray directs the Department of Global Health and Social Medicine Research Core; she is also director of research for the Division of Global Health Equity at Brigham and Womens Hospital.. ...
Dr. Warren Murray Jr, MD of New Bern, NC patient reviews, appointments, phone number and quality report. Compare Dr. Murray to other nearby Internal Medicine Physicians in North Carolina.
Rated 0 of 5 stars 0 Reviews of Doctor Thomas Murray - Doctor Thomas Murray is a graduate of Cleveland Chiropractic College, Overland Park,...
http://groups.yahoo.com/group/aspartameNM/message/1024 aspartame review: methanol, formaldehyde, formic acid toxicity: Murray 9.5.3 rmforall Rich Murray, MA Room For All [email protected] 1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103 **********************************************************************************************
http://groups.yahoo.com/group/aspartameNM/message/1024 aspartame review: methanol, formaldehyde, formic acid toxicity: Murray 9.5.3 rmforall Rich Murray, MA Room For All [email protected] 1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103 **********************************************************************************************
Dr. Emilia Murray, MD of Naples, FL patient reviews, appointments, phone number and quality report. Compare Dr. Murray to other nearby Internal Medicine Physicians in Florida.
Dr. Joseph E. Murray, the Nobel laureate who conducted the worlds first successful organ transplant, died Monday at the Boston hospital where the pioneering surgery was performed. He was 93. He had suffered a hemorrhagic stroke at his Wellesley home Thanksgiving night. On Dec. 23, 1954, in Operating Room 2 of Peter Bent Brigham Hospital, Dr. Murray took the healthy kidney of Ronald Herrick and sutured it into the donors dying identical twin, Richard.
The Robert W. Murray Lecture is an endowed lecture series established in 1998 to honor the the distinguished research career and many contributions to the UM-St. Louis campus during the more than 30-year career of the late Dr. Robert W. Murray, Curators Professor Emeritus 1928 - 2012.. 2017. Karen L. Wooley, W. T. Doherty-Welch Chair in Chemistry, University Distinguished Professor at Texas A&M University where she holds appointments in the Departments of Chemistry, Chemical Engineering and Materials Science & Engineering. She also serves as Director of the Laboratory for Synthetic-Biologic Interactions.. 2016. Michael J. Krische, Professor of Chemistry at the University of Texas-Austin, Director, Center for Green Chemistry and Catalysis, Robert A. Welch Chair in Science and a faculty member in the Environmental Science Institute ...
Find hope in a bottle. Andrew Murray Vineyards Espérance 2008 is a wine to drink if youve lost hope, dont despair, it will restore lost faith. Espérance is the French word for hope. And nothing is lost in translation here. This wine is a Rhône blend, in the trade its refered to as a GSM for the grapes used, grenache, syrah and mourvedre. The flavors are hyptonic, dark cherry and blackberries with a pronounced spiceiness. The tannins are well-intergated and its a beautifully crafted wine. The perfect pairing is Filet Mignon with Bordelaise Sauce. The music match is Hope for the Hopeless from A Fine Frenzy from the album One Cell in the Sea. Find hope with Andrew Murrays Espérance.. The details: 14.8% alcohol. Screw cap closure. Appellation: Central Coast (grenache noir from Terra Bealla Vineyard, Paso Robles; syrah from Watch Hill, Santa Ynez Valley, mourvedre from Brave Oak Vineyard, Paso Robles.) Varietials: 60% grenache noir, syrah 25%, mourvedre 15%. The suggested retail is $30 ...
The family-owned company will build the new facility on a greenfield site, 10km from the town centre, creating an initial 400 jobs before swelling to 2000 employees once fully operational.. Thomas Foods International CEO Darren Thomas says the rebuild is the single largest investment by the company in its 30-year history and on a scale not seen in our industry for many years.. Today we re-affirm the commitment we made on day one, he says.. We plan to build the best, most advanced multi-species processing facility in Australia, if not the world. And we will build it at Murray Bridge in South Australia.. We want out facility to be world-class in adapting the latest advancements in technology, efficiency, environmental sustainability, animal welfare and workplace safety.. The new plant will be built in stages with the beef processing facilities to be completed first. The final stages of the development will provide for a considerable expansion and greater footprint compared to the previous ...
A major step in Thomas Foods Internationals planned new multi-million dollar abattoir at Murray Bridge occurred this week with the first sod turned on the new public access road to the facility.
Desilva, Sena, Gunasekera, RM and Gooley, G 2000, Digestibility and amino acid availability of three protein-rich ingredient-incorporated diets by Murray cod Maccullochella peelii peelii (Mitchell) and the Australian shortfin eel Anguilla australis Richardson, Aquaculture Research, vol. 31, no. 2, pp. 195-205, doi: 10.1046/j.1365-2109.2000.00432.x. ...
Murray Rothbard said:. [Defenders of government usually say] freedom of the market should be upheld and that property rights must not be invaded. Nevertheless, they strongly believe that defense service cannot be supplied by the market and that defense against invasion of property must therefore be supplied outside the free market, by the coercive force of the government. In arguing thus, they are caught in an insoluble contradiction, for they sanction and advocate massive invasion of property by the very agency (government) that is supposed to defend people against invasion! [...]. The [defender of government] assumes that there must be a single compulsory monopoly of coercion and decision-making in society, that there must, for example, be one Supreme Court to hand down final and unquestioned decisions. But he fails to recognize that the world has lived quite well throughout its existence without a single, ultimate decision-maker over its whole inhabited surface. The Argentinian, for example, ...
The re-population of an iconic crayfish in Australias biggest river system is on track.. Murray Crayfish numbers were decimated in the Murray River during widespread hypoxic blackwater events during flooding in 2010 and 2011.. But for the past three years a stocking program has been relocating Murray Crayfish to the mid-lower Murray area.. New South Wales DPI Senior Fisheries Manager Dr Trevor Daly told Macquarie National News Rural Reporter Eddie Summerfield human intervention was needed.. For them to move a couple of hundred kilometres downstream would take decades, Dr Daly said. ...
The re-population of an iconic crayfish in Australias biggest river system is on track.. Murray Crayfish numbers were decimated in the Murray River during widespread hypoxic blackwater events during flooding in 2010 and 2011.. But for the past three years a stocking program has been relocating Murray Crayfish to the mid-lower Murray area.. New South Wales DPI Senior Fisheries Manager Dr Trevor Daly told Macquarie National News Rural Reporter Eddie Summerfield human intervention was needed.. For them to move a couple of hundred kilometres downstream would take decades, Dr Daly said. ...
All about Ruminant immunity to abosomal parasites. PhD thesis, University of Edinburgh. by Aileen Murray Halliday. LibraryThing is a cataloging and social networking site for booklovers
2017) DNA metabarcoding for diet analysis and biodiversity: A case study using the endangered Australian sea lion (Neophoca cinerea). Ecology and Evolution, 7 (14). pp. 5435-5453. Coghlan, M.L., Maker, G., Crighton, E., Haile, J., Murray, D.C., White, N.E., Byard, R.W., Bellgard, M.I., Mullaney, I., Trengove, R., Allcock, R.J.N., Nash, C., Hoban, C., Jarrett, K., Edwards, R., Musgrave, I.F. and Bunce, M. ...
British tennis star Andy Murray is hungry for his first Grand Slam title, and is building up his muscles and resistance capability on a bizarre daily diet of sushi and peanut butter.
They went on trial before a jury in U.S. District Court in the Western District of Louisiana. Prior to the trial, the prosecution filed a motion to limit defense cross-examination of Murray regarding his prior arrests and personal drug use. U.S. District Court Judge Tucker Melancon ruled that Murray could be cross-examined about the circumstances and his motivations in relation to his cooperation with law enforcement in Texas. The judge, however, barred defense attorneys from questioning Murray about a purse-snatching arrest in Louisiana that occurred after he began cooperating with authorities or from questioning Murray about the penalties he faced if he was convicted of the Texas or Louisiana charges ...
Learn about Murray State University genetics course. Seek out accredited nursing programs for the best training. Given a brief hospital internship or prior work experience, you can expect a great return on your medical education.
The Groups risk management framework facilitates identification and management of risks and opportunities in a manner that supports value creation. Risk management is an integral part of all decision-making processes and day-today activities.. Murray & Roberts operates in an environment that presents opportunities and risks that can have a financial, operational and reputational impact on the business. Entrusted with the overall responsibility for risk management, the Board sets the direction through policies and frameworks on how these risks and opportunities should be managed.. The Groups market sector, geographic and project life cycle diversification is instrumental in mitigating some of the risks we face. The shift to broaden market focus over the last three years has become a permanent feature of the Groups response to cyclicality in natural resources markets.. Appropriate governance structures, including the Board risk committee, executive risk committee, project oversight committee ...
Precision Eye Care is your local Optometrist in Murray serving all of your needs. Call us today at (801) 262-2020 for an appointment.
Im actually a little surprised that it took this long for an interview with Conrad Murray to hit the internet - guess prices had to be negotiated carefully
Bob Murray rose from coal miner to executive and became an influential industry voice. Despite his role in crafting the Trump administrations pro-coal policies, his own company is bankrupt.
Media sources, reviewing the evidence given by Murray about Michaels death, question timelines in the Las Vegas search warrant.
Isolation of Murray Valley encephalitis and other viruses from mosquitoes in north Queensland. Australian Journal of Science, ... The wife of Ian Murray Mackerras, Josephine was awarded the Clarke Medal in 1965. In 1966, she was elected a fellow of the ... During her time at the University of Sydney, she met Ian Murray Mackerras, her future husband. The young couple enjoyed sailing ... Doherty, R. L., Carley, J. G., Mackerras, M. J., & Marks, E. N. (1963). Studies of arthropod-borne virus infections in ...
At the Hall Institute he initially worked on the viruses that cause influenza and Murray Valley encephalitis. He was the first ... to establish that influenza is an RNA virus and was awarded his DSc by the University of Sydney in 1959. From 1962 he focused ...
It can also infect Murray Valley encephalitis in Australia. "An annotated checklist of mosquitoes of Sri Lanka" (PDF). Man and ... Adults and larva can be naturally infected with Wuchereria bancrofti and Batai virus in India, and Burgia malayi in Sri Lanka. ...
M. uniformis can be a vector of human diseases, such as Ross River virus, Kunjin virus, Murray Valley encephalitis, and ...
In 1960, QIMR Berghofer scientists isolated Murray Valley encephalitis virus from mosquitoes, which paved the way for discovery ... Epstein-Barr virus, Ross River virus, scabies, dengue fever and schistosomiasis (blood flukes) Mental health, including ... "Mackerras, Ian Murray (1898-1980)" (published first in hardcopy 2000). Australian Dictionary of Biography, National Centre of ... Eight years later, this same virus was found to immortalise white blood cells; a discovery that revolutionised research of ...
Groth, and Frank Fenner made significant contributions on Murray Valley encephalitis, myxomatosis, poliomyelitis, poxviruses, ... He made a vaccine for the Q virus He was awarded the Beit Memorial Fellowship by the Lister Institute in 1926; this gave him ... He brought back a set of viruses from the National Institute to begin the basis of research in Melbourne. When Burnet returned ... His own research was on the canarypox virus, which he used in developing a chick embryo assay for the isolation and ...
Japanese encephalitis, chikungunya and filariasis in Africa and Asia; and Murray Valley encephalitis in Australia. Depending on ... Eastern equine encephalomyelitis virus, Everglades virus, Highlands J virus, La Crosse Encephalitis virus in the United States ... Disease organisms transmitted by mosquitoes include West Nile virus, Saint Louis encephalitis virus, ... dengue fever, yellow fever, Ilheus virus, malaria, Zika virus and filariasis in the American tropics; Rift Valley fever, ...
... where he studied Murray Valley encephalitis virus and respiratory viruses alongside Macfarlane Burnet. Marmion returned to the ... He moved to Leeds as the head of the new PHLS virus laboratory in 1955. At Leeds, he published the first description of Q fever ... This investigation laid the groundwork for the principles of bloodborne virus control that would later be applied to HIV. In ... working in the virus reference laboratory at the latter. In 1951, he was awarded a Rockefeller Fellowship allowing him to ...
Murray Valley encephalitis, Ross River virus, West Nile virus, Yellow Fever, Zika virus Aedes africanus Aedes albolineatus ... California encephalitis virus, Eastern equine encephalitis, Jamestown Canyon virus, Sindbis virus, West Nile virus Aedes clivis ... carries California encephalitis virus, Keystone virus, trivittatus virus, West Nile virus, Western equine encephalitis Aedes ... carries Cache Valley virus, chikungunya, dengue fever, Eastern equine encephalitis, West Nile virus, Yellow Fever, Zika virus ...
Murray Valley encephalitis virus (MVEV) - Major mosquito vector: Culex annulirostris. Japanese encephalitis - Several mosquito ... West Nile virus - Vectors: vary according to geographical area; in the United States Culex pipiens (Eastern US), Culex tarsalis ... Houseflies also transmit poliomyelitis by carrying the virus from infected faeces to food or drink. Cholera and hepatitis are ... Lyme disease - Vectors: several species of the genus Ixodes Alkhurma virus (KFDV) - Vector: tick Kyasanur forest disease - ...
... including Murray Valley encephalitis virus, Ross River virus, Barmah Forest virus, Kunjin virus and Japanese encephalitis, as ...
... of Murray Valley Murray River valley Murray Valley Highway Murray Valley National Park Murray Valley encephalitis virus This ... disambiguation page lists articles associated with the title Murray Valley. If an internal link led you here, you may wish to ... Murray Valley may refer to: Electoral district ...
... encephalitis virus, murray valley MeSH B04.820.250.350.300.330 - encephalitis virus, st. louis MeSH B04.820.250.350.300.950 - ... encephalitis virus, murray valley MeSH B04.909.777.270.475.330 - encephalitis virus, st. louis MeSH B04.909.777.270.475.950 - ... encephalitis virus, murray valley MeSH B04.909.777.310.350.300.330 - encephalitis virus, st. louis MeSH B04.909.777.310.350.300 ... la crosse virus MeSH B04.909.777.270.150 - encephalitis virus, eastern equine MeSH B04.909.777.270.369 - encephalitis virus, ...
... virus Murray Valley encephalitis virus Nipah virus Powassan virus Rabies virus Rubella virus SARS-CoV-2 Snowshoe hare virus St ... California encephalitis virus Chandipura virus Chikungunya virus Cytomegalovirus Dengue virus Eastern equine encephalitis virus ... shingles Venezuelan equine encephalitis virus West Nile virus Western equine encephalitis virus Zika virus Encephalitic viruses ... Louis virus Tahyna virus Tick-borne encephalitis virus Varicella-zoster virus, which causes both chickenpox and ...
Both forms of Kunjin virus disease are milder than the diseases caused by West Nile virus and Murray Valley encephalitis virus ... "Murray Valley Encephalitis virus & Kunjin virus". University of Sydney-Department of Medical Entomology. Retrieved 2009-08-08 ... Kunjin virus (KUNV) is a zoonotic virus of the family Flaviviridae and the genus Flavivirus. It is a subtype of West Nile virus ... Kunjin virus is a zoonotic virus of the family Flaviviridae and the genus Flavivirus. It is an arbovirus which is transmitted ...
Louis encephalitis, Japanese encephalitis and Murray Valley encephalitis viruses. During 1975 and 1976, Rocio virus was ... The encephalitis outbreak in the western hemisphere caused by West Nile virus, a related flavivirus, highlights the potential ... The causative Rocio virus belongs to the genus Flavivirus (the same genus as the Zika virus) in family Flaviviridae and is ... Strains of Rocio virus were isolated from the blood of a rufous-collared sparrow, Zonotrichia capensis. Rocio virus was also ...
... human-pathogenic viruses such as West Nile and Murray Valley encephalitis viruses were found to be unable to develop in the ... flavivirus from northern Australia suppresses replication of West Nile virus and Murray Valley encephalitis virus in co- ... The virus is named after Palm Creek, near Darwin, from where it was originally isolated. PCV is the first insect-specific virus ... Palm Creek virus (PCV) is an insect virus belonging to the genus Flavivirus, of the family Flaviviridae. It was discovered in ...
... together with Japanese encephalitis virus, Murray Valley encephalitis virus, Saint Louis encephalitis virus and some other ... The mature viruses are then secreted out of the cell. WNV is one of the Japanese encephalitis antigenic serocomplex of viruses ... The virus is genetically related to the Japanese encephalitis family of viruses. Humans and horses both exhibit disease ... dengue virus, and yellow fever virus. West Nile virus is primarily transmitted by mosquitoes, mostly species of Culex. The ...
... (MVEV) is a zoonotic flavivirus endemic to northern Australia and Papua New Guinea. It is the ... "Murray Valley encephalitis virus infection-Fact Sheet". Department of Health and Ageing. Archived from the original on 18 ... Hurrelbrink RJ, Nestorowicz A, McMinn PC (1 December 1999). "Characterization of infectious Murray Valley encephalitis virus ... The virus was isolated from human samples in 1951 during an epidemic in the Murray Valley, Australia. Epidemics usually occur ...
Murray Valley encephalitis virus (MVEV) Alfuy virus St. Louis encephalitis virus (SLEV) Usutu virus (USUV) West Nile virus (WNV ... virus Murray Valley encephalitis virus Ntaya virus Omsk hemorrhagic fever virus Phnom Penh bat virus Powassan virus Rio Bravo ... virus Saumarez Reef virus Sepik virus Tembusu virus Tick-borne encephalitis virus Tyuleniy virus Uganda S virus Usutu virus ... virus Japanese encephalitis virus Jugra virus Jutiapa virus Kadam virus Kedougou virus Kokobera virus Koutango virus Kyasanur ...
Dengue fever Hepatitis C Japanese encephalitis Kyasanur Forest disease Murray Valley encephalitis St. Louis encephalitis Tick- ... GB virus B)) Genus Pegivirus (includes Pegivirus A (GB virus A), Pegivirus C (GB virus C), and Pegivirus B (GB virus D)) Genus ... Guaico Culex virus, Jingmen tick virus and Mogiana tick virus. These viruses have a segmented genome of 4 or 5 pieces. Two of ... type species Yellow fever virus, others include West Nile virus, Dengue virus, and Zika virus). Genus Hepacivirus (type species ...
Dengue virus group Dengue virus Japanese encephalitis virus group Japanese encephalitis virus Murray Valley encephalitis virus ... Louis encephalitis virus West Nile virus Spondweni virus group Spondweni virus Zika virus Yellow fever virus group Yellow fever ... Eastern equine encephalitis virus Ross River virus Venezuelan equine encephalitis virus Western equine encephalitis virus' ... virus Tick-borne viruses Mammalian tick-borne virus group Kyasanur forest disease virus Tick-borne encephalitis virus Family ...
Australian encephalitis(英语:Murray Valley encephalitis virus) *MVEV(英语:Murray Valley encephalitis virus) ... 虫媒病毒性脑炎:Tick-borne encephalitis(英语:Tick-borne encephalitis) *TBEV(英语:Tick-borne encephalitis virus) ... California encephalitis(英语:California encephalitis) *CEV(英语:California encephalitis virus) ... 圣路易斯脑炎(英语:Saint Louis encephalitis) *SLEV(英语:St.
Australian encephalitis(英語:Murray Valley encephalitis virus) *MVEV(英語:Murray Valley encephalitis virus) ... 蟲媒病毒性腦炎:Tick-borne encephalitis(英語:Tick-borne encephalitis) *TBEV(英語:Tick-borne encephalitis virus) ... California encephalitis(英語:California encephalitis) *CEV(英語:California encephalitis virus) ... 聖路易斯腦炎(英語:Saint Louis encephalitis) *SLEV(英語:St.
"History of major virus outbreaks in the UK in recent times". Express and Star. 3 March 2020. Retrieved 13 December 2020. ... John Murray. p. 283. ISBN 978-1-84854-470-3. Mitchell, Cameron (19 February 2016). "The case of suspected Irish serial killer ... "Oaks Disaster Victims". Dearne Valley Landscape Partnership. Archived from the original on 15 October 2016. Retrieved 13 ... The Enigma of von Economo's Encephalitis Lethargica". Journal of Neuropathology and Experimental Neurology. 60 (7): 665. doi: ...
death announced on this date) Murray Feshbach, 90, American economist. Salvador Freixedo, 96, Spanish ufologist and priest. ... Paul Crosby, 30, American basketball player (Mississippi Valley State, Minas), traffic collision. Ron Fairly, 81, American ... complications from Powassan virus. Piyare Jain, 97, Indian particle physicist. Zoltán Jeney, 76, Hungarian composer. Dean L. ... of legendary Wexford goalkeeper Art Foley Former US Senator Kay Hagan dead at 66 after three-year battle with encephalitis ...
Allworth, A.; Murray, K.; Morgan, J.A. (1996). "Human case of encephalitis due to a lyssavirus recently identified in fruit ... Hendra virus, Australian bat lyssavirus and Menangle virus. However, only Australian bat lyssavirus is known from two isolated ... The forced relocations are also said to have led to the discovery of the orchards of the Goulburn Valley. Similarly, the first ... Negative public perception of the species has intensified with the discovery of three recently emerged zoonotic viruses that ...
"Murray Rosenblatt Obituary - San Diego, CA". Dignity Memorial. "David Weisman, 'Kiss of the Spider Woman' Producer, Dies at 77 ... "Valley anti-war activist Frances Crowe dies at 100". Daily Hampshire Gazette. August 27, 2019. "Senator Deddeh Obituary - ... Former US Senator Kay Hagan dead at 66 after three-year battle with encephalitis "State legislator, civil-rights attorney John ... Sheikh, Knvul (September 27, 2019). "Joachim Messing, 73, Who Charted the DNA of Viruses and Plants, Dies" - via NYTimes.com ...
... and Venezuelan equine encephalitis virus. In 1971, weaponized smallpox from the island reached a nearby ship, which then ... Craig Murray, UK ambassador to Uzbekistan in 2002, attributes the shrinkage of the Aral Sea in the 1990s to president Islam ... of farmland in the Ferghana Valley. The Aral Sea region is heavily polluted, with consequent serious public health problems. ... Craig Murray (2007). Dirty Diplomacy. Scribner. Greenberg, Ilan (7 April 2006). "A vanished sea reclaims its form in Central ...
La Crosse virus was first recognized in a fatal case of encephalitis in La Crosse, Wisconsin 1977: Rift Valley Fever virus ... PMID 22933273 Patrick R. Murray, Ken S. Rosenthal and Michael A. Pfaller (2008-12-24). Medical Microbiology, 6e (6 ed.). ... California encephalitis virus, La Crosse encephalitis virus, Jamestown Canyon virus and Snowshoe hare virus vector: mosquitoes ... As precautions Cache Valley virus and Hantavirus research are conducted in BSL-2 (or higher), Rift Valley Fever virus research ...
Japanese encephalitis virus (JE) Kyasanur Forest virus LaCrosse virus (LACV) Venezuelan equine encephalitis (VEE) Western ... Junin virus, Machupo virus, Guanarito virus, Lassa fever Bunyaviruses: Hantaviruses, Rift Valley Fever, Crimean-Congo ... ISBN 978-0-19-990905-6. Murray KA, Allen T, Loh E, et al. (2015). "Emerging Viral Zoonoses from Wildlife Associated with Animal ... Omsk Hemorrhagic Fever virus, Alkhurma virus, Kyasanur Forest virus (reclassified from B to C) Powassan virus (Deer Tick virus ...
... lymphocytic encephalitis. This virus was carried on a beacon left by the Thirteenth Tribe at the Lion's Head Nebula millennia ... access-date= requires ,url= (help) "Valley of Darkness", Wikipedia, 2020-06-19, retrieved 2020-07-09 "Battlestar Galactica: ... voiced by Murray Matheson). Two additional IL-Series Cylons are shown on-screen on the Cylon capitol of Gamoray during the ... The canister contained an airborne virus that proved deadly to the Cylons. The virus persisted through the download process so ...
Virus Sections. Virus Name/Prototype. Original Source. Method of Isolation. Virus Properties. Antigenic Relationship. Biologic ... SECTION I - Full Virus Name and Prototype Number. Prototype Strain Number / Designation. MVE/1/1951 Accession Number. Original ... Click on the PDF icon to the left to view a copy of this virus entry in PDF format. You can get a copy of the PDF viewer by ... Virus Name: Murray Valley encephalitis Abbreviation: MVEV Status. Arbovirus Select Agent. No SALS Level. 3 ...
What is Murray Valley encephalitis?. Murray Valley encephalitis virus is spread to people through the bite of an infected ... What can travelers do to prevent Murray Valley encephalitis?. There are no vaccines or medicines that prevent Murray Valley ... Symptoms of Murray Valley encephalitis can include fever, headache, nausea, vomiting, and tiredness. Some people may develop ... Murray Valley Encephalitis virus. *Zika Travel Information. ... are at risk for being infected with Murray Valley encephalitis. ...
Regnum: Virus. Group IV: ssRNA(+) Ordo: Unassigned Familia: Flaviviridae Genus: Flavivirus. Species: Murray Valley encephalitis ... Retrieved from "https://species.wikimedia.org/w/index.php?title=Murray_Valley_encephalitis_virus&oldid=6037623" ...
NAME: Murray Valley encephalitis SYNONYM OR CROSS REFERENCE: MVE, Australian X disease, Australian encephalitis, mosquito-borne ... encephalitis, viral encephalitis, arbovirus CHARACTERISTICS: This virus is part of the Flavivirus genus and is an enveloped, ... Murray Valley encephalitis virus. Murray Valley encephalitis. PATHOGEN SAFETY DATA SHEET - INFECTIOUS SUBSTANCES ... EPIDEMIOLOGY: The MVE virus is present in Australia and New Guinea. The last major outbreak occurred in Australia in 1974 (58 ...
Murray valley encephalitis virus (strain MVE-1-51). Mutation(s): 0 EC: 3.4.21.91 (PDB Primary Data), 3.6.1.15 (UniProt), 3.6. ... Here we report the 2.75-A-resolution crystal structure of full-length Murray Valley encephalitis virus NS3 fused with the ... Find proteins for P05769 (Murray valley encephalitis virus (strain MVE-1-51)) ... Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus. *DOI: 10.2210/pdb2WV9/pdb ...
A Murray Valley encephalitis virus (MVE) field isolate of high neuroinvasiveness (BH3479) and a neutralization escape variant ... A comparison of the spread of Murray Valley encephalitis viruses of high or low neuroinvasiveness in the tissues of Swiss mice ... All BH3479-infected mice developed encephalitis and died before 10 days pi. In contrast, BHv1 was not detected in lymph nodes ... Both viruses appeared to enter the CNS via the olfactory lobes. BH3479 spread throughout the CNS in a rostral to caudal ...
However, infection, including Murray Valley encephalitis virus (MVEV) - peak risk February to July - was considered in the ... Extended detection and isolation of Murray Valley encephalitis virus in whole blood and urine. ... The most likely diagnosis was thought to be encephalitis associated with systemic lupus erythematosus, and she initially ...
The differential diagnosis for travel-associated encephalitis should include MVEV, particularly during outbreak years. ... a flavivirus belonging to the Japanese encephalitis serogroup, can cause severe clinical manifestations in humans. We report a ... Fatal Infection with Murray Valley Encephalitis Virus Imported from Australia to Canada, 2011 Daniel J. Niven, Kevin Afra, ... Fatal Infection with Murray Valley Encephalitis Virus Imported from Australia to Canada, 2011. ...
... of Murray Valley encephalitis virus in these two species of mosquitoes and to determine if they could transmit this virus. ... Virus multiplication was demonstrated in both species of mosquitoes following ingestion of blood from viremic chicks. The ... to determine if Japanese B encephalitis virus could interfere with the transmission of Murray Valley encephalitis virus by C. ... The Behavior of Murray Valley Encephalitis Virus in Culex Tritaeniorhynchus Giles and Culex Pipiens Quinquefasciatus Say * * ...
Murray Valley encephalitis (MVE) virus was isolated in 8 of the 13 years of the study from seven mosquito species, but more ... Activity of MVE virus could only be partially correlated with wet season rainfall and flooding, suggesting that a number of ... The results suggest that MVE virus is epizootic in the region, with activity only apparent in years with average or above ... High levels of MVE virus activity and associated human cases were detected only once (in 1993) during the survey period. ...
To assess evidence of recent and past exposure to Murray Valley encephalitis virus (MVEV) and West Nile clade Kunjin virus ( ... Low seroprevalence of Murray Valley Encephalitis and Kunjin viruses in an opportunistic serosurvey, Victoria 2011.. Williams SA ... Low seroprevalence of Murray Valley Encephalitis and Kunjin viruses in an opportunistic serosurvey, Victoria 2011. ... in residents of the Murray Valley, Victoria, during a period of demonstrated activity of both viruses in early 2011. Methods: A ...
... and examined the virulence of the passaged virus for 21-day-old mice following intracranial and intraperitoneal inoculation. ... We have passaged the prototype strain of Murray Valley encephalitis virus in SW13 (human) cells, sequenced the E and M genes, ... We have passaged the prototype strain of Murray Valley encephalitis virus in SW13 (human) cells, sequenced the E and M genes, ... Host cell selection of Murray Valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in ...
March 2002 contains a report on 5 laboratory-confirmed cases of encephalitis which occurred over a short period in the normally ... Reappearance of human cases due to Murray Valley encephalitis virus and Kunjin virus in Central Australia after an absence of ... Murray Valley encephalitis (MVE) and Kunjin virus disease are endemic in the tropical parts of the Northern Territory and ... Murray Valley encephalitis virus surveillance and control initiatives in Australia. Commun Dis Intell 2001;25:33-47. 9. Russell ...
Supernatants from infected cells protected Vero cells from c.p.e. and caused up to a 95% reduction of wild-type virus yield. ... The genetic drift of the parental virus during the course of a long term persistent infection in vitro appears to be minimal. ... However, results from this study suggest that DI particles of MVE virus differ from other studied systems in that they are able ... virus strain OR2 was serially passaged on Vero cells to establish a persistent infection which was maintained for over 300 days ...
... which occurred at a reduced rate and to a lesser extent than for wild-type virus. Fusion was inhibited by monoclonal antibodies ... A neutralization escape variant of Murray Valley encephalitis virus (MVE), of low neuroinvasiveness in mice and with low ... A Mouse-attenuated Envelope Protein Variant of Murray Valley Encephalitis Virus with Altered Fusion Activity * Peter C. McMinn ... A neutralization escape variant of Murray Valley encephalitis virus (MVE), of low neuroinvasiveness in mice and with low ...
Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses. / Mackenzie, J.S.; ... Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses. Microbiology Australia ... title = "Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses", ... T1 - Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses ...
"Murray Valley encephalitis virus" virus name. The additional filters enable you with creating a sub-selection of items of this ... For tropical and RG4 viruses. In the event of a major biological incident regarding tropical (exotic) viruses or Risk Group 4 ... For other human viruses of medical importance. The University hospital of Bonn is in charge of our hotline dedicated to other ... distribute and track viruses and derived products. ... Use any term of the related virus lineage (combine with commas ...
"Murray Valley encephalitis virus" virus name. The additional filters enable you with creating a sub-selection of items of this ... Murray Valley encephalitis virus Riboviria / Orthornavirae / Kitrinoviricota / Flasuviricetes / Amarillovirales / Flaviviridae ... Freeze-dried Murrey Valley Encephalitis Virus strain UVE/MVEV/UNK/AU/3329, Australia, complete ORF sequence. ... Filter by Virus host type. *Human virus (1) Apply Human virus filter ...
... 132231_13899_ARA10_Williams.pdf (749.8Kb) ... Molecular characterization of Murray Valley encephalitis virus, in Ryan, P. and Aaskov, J. and Russell, R. (ed), 10th Arbovirus ...
Using site-directed mutagenesis at the NS1-2A cleavage site of Murray Valley encephalitis virus (MVEV), we confirmed the ... Thus, comparison of the impact on cleavage of mutations at the NS1-2A junction of MVEV and DENV showed virus-specific ... at the NS1-2A junction in the flavivirus polyprotein has not markedly progressed since the early work conducted on dengue virus ... From: Proteolytic cleavage analysis at the Murray Valley encephalitis virus NS1-2A junction ...
g4virus/murray_valley_encephalitis_virus.txt · Last modified: 2018/07/31 12:43 (external edit) ... Statistical evidence for the calculated G4s in the human virus genomes. The presence of G4 patterns may be largely affected by ... Conservation of G-quadruplexes and virus genomes. The presence of a conserved G-quadruplex (G4) pattern within a less conserved ... Local sequence conservation: it is the sequence conservation among all strains available for each virus, calculated with a ...
Murray Valley encephalitis, Kunjin, Japanese encephalitis and yellow fever) and malaria. The report also inlcudes data on the ... Murray Valley encephalitis virus (MVEV) infection, Kunjin virus (KUNV) infection and Japanese encephalitis virus (JEV) ... Murray Valley encephalitis virus infection There were 4 notifications of locally-acquired MVEV in Australia resulting in 2 ... flocks across Australia provides an early warning of increased levels of Murray Valley encephalitis virus and Kunjin virus ...
The Murray Valley encephalitis virus is a type of arbovirus spread by mosquitoes. ... Murray Valley Encephalitis Virus. The Murray Valley encephalitis (MVE) virus, (a flavivirus), is a type of arbovirus spread by ... Murray Valley encephalitis virus infection is known to occur in northern Australia where sporadic human cases or small ... Murray Valley encephalitis is not a notifiable disease of horses in Victoria - however owners should discuss the health of ...
Phylogeny of Murray Valley Encephalitis Virus in Australia and Papua New Guinea Eleonora Cella 1 , Ivan Gabrielli 2 , ... Phylogeny of Murray Valley Encephalitis Virus in Australia and Papua New Guinea Eleonora Cella et al. Asian Pac J Trop Med. ... Objective: To study the genetic diversity of Murray Valley encephalitis virus (MVEV) in Australia and Papua New Guinea. ... The Molecular Epidemiology and Evolution of Murray Valley Encephalitis Virus: Recent Emergence of Distinct Sub-lineages of the ...
Murray valley encephalitis virus (ATCC® VR-77™) ATCC® Number: VR-77™ Classification: Flaviviridae, Flavivirus ... Monoclonal Anti-Dengue virus type 3 envelope protein, Clone E11 (produced in vitro) (ATCC® VR-1692™) ATCC® Number: VR-1692™ ... Strain: Monoclonal antibody to West Nile virus Envelope Protein, Clone E58 (produced in vitro) ... Source: Mouse monoclonal antibody prepared against the envelope glycoprotein of Dengue virus type 3 (DEN-3) was purified from ...
... 187635_187635.pdf (91.49Kb) ... Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. Journal of Veterinary ... This is the first confirmed case of naturally-occurring equine encephalitis attributable to Murray Valley encephalitis virus ... Background Murray Valley encephalitis virus (MVEV) is a flavivirus that occurs in Australia and New Guinea. While clinical ...
April 2001 contains an in-depth report on surveillance and control initiatives in place for Murray Valley encephalitis in ... Murray Valley encephalitis, 1974: clinical features. Med J Aust 1976;2:446-50. 7. Marshall ID. Murray Valley and Kunjin ... Murray Valley encephalitis and the French connection. Veterinary Microbiology 1995;46:79-90. 5. Forbes JA. Murray Valley ... MVE virus is enzootic in the Northern Territory and cases of Murray Valley encephalitis have been reported in a number of years ...
Explainer: what is Murray Valley encephalitis virus?. Venezuelans demonstrate outside a childrens hospital in Caracas. MIGUEL ... The Culex annulirostris mosquito and waterbirds are responsible for spreading Murray Valley encephalitis. Paul Zborowski ... had already reported finding haemorrhagic fever viruses, including Ebola virus, in the forests of Liberia. ... This was meant to apply even to members of the Zaire ebolavirus species (an Ebola virus), one of which now ravages West Africa ...
Murray Valley encephalitis virus is a rare but potentially fatal mosquito-borne virus. Heres what you need to know about it. ... Explainer: what is Murray Valley encephalitis virus?. Ana Ramírez, James Cook University; Andrew Francis van den Hurk, The ... The Culex annulirostris mosquito and waterbirds are responsible for spreading Murray Valley encephalitis. Paul Zborowski ...
  • CHARACTERISTICS: This virus is part of the Flavivirus genus and is an enveloped, spherical, positive-strand RNA virus(1,2,3). (msdsonline.com)
  • Murray Valley encephalitis virus (MVEV) is a zoonotic flavivirus endemic to northern Australia and Papua New Guinea. (wikipedia.org)
  • We undertook annual surveys of flavivirus virus activity in the community of Billiluna of Western Australia in the southeast Kimberley region between 1989 and 2001. (ajtmh.org)
  • Sentinel chicken flocks are employed as a means of early warning of MVE and KUN virus activity by testing for general and specific flavivirus seroconversion. (health.gov.au)
  • Detection of flavivirus seroconversions in sentinel chicken flocks across Australia provides an early warning of increased levels of Murray Valley encephalitis virus and Kunjin virus activity. (health.gov.au)
  • Pan-flavivirus reverse transcription PCR performed for nucleic acids extracted from central nervous system tissue biopsy specimens obtained at autopsy from a patient with a fatal infection of Murray Valley encephalitis virus imported from Australia to Canada, 2011. (cdc.gov)
  • lane +, flavivirus-positive control (expected amplicon size 854-863 bp depending on virus species). (cdc.gov)
  • Background Murray Valley encephalitis virus (MVEV) is a flavivirus that occurs in Australia and New Guinea. (edu.au)
  • Murray Valley encephalitis disease (MVEV) Cyclobenzaprine HCl can be a mosquito-borne flavivirus owned by japan encephalitis disease (JEV) serocomplex that may cause severe, fatal sometimes, disease in human beings (evaluated in referrals 30, 31, 32, and 42). (biotechnologysymposium.com)
  • A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), found in Australia and New Guinea. (bioportfolio.com)
  • A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), which is the etiological agent of Japanese encephalitis found in Asia, southeast Asia, and the Indian subcontinent. (bioportfolio.com)
  • Japanese encephalitis virus (JEV) is a representative virus of the JEV serogroup in genus Flavivirus, family Flaviviridae. (bioportfolio.com)
  • An epidemic encephalitis or encephalomyelitis of Japan, Siberia, and other parts of Asia, caused by a mosquito-borne flavivirus. (thefreedictionary.com)
  • Out of 580 wild-caught mosquitoes from 124 pools tested for virus using antigen capture ELISA and an insect-bioassay (inoculation into Toxorhynchites splendens larvae and identification by IFA using Japanese encephalitis (JE) virus-specific monoclonal antibody), four flavivirus isolations were made, of which 2 (50%) were identified as JE virus, one each from Culex tritaeniorhynchus and Cx. (thefreedictionary.com)
  • it is caused by the Murray Valley encephalitis virus (genus Flavivirus). (thefreedictionary.com)
  • The genus Flavivirus includes arthropod-borne viruses responsible for a large number of infections in humans and economically important animals. (hindawi.com)
  • The genus Flavivirus contains nearly 70 recognized viruses, many of which infect humans and economically important animals [ 1 ]. (hindawi.com)
  • Kunjin virus (KUNV) is a zoonotic virus of the family Flaviviridae and the genus Flavivirus. (wikipedia.org)
  • Zika virus (ZIKV) is a previously little-known flavivirus closely related to Japanese encephalitis, West Nile, dengue, and yellow fever viruses, all of which are primarily transmitted by blood-sucking mosquitoes. (springer.com)
  • West Nile virus (WNV, Flaviviridae , Flavivirus ) is an emerging zoonotic arbovirus ( art hropod- bo rne virus ) widely distributed throughout the world and with considerable impact both on public health and on animal health [ 1 ]. (mdpi.com)
  • Cryo-electron microscopy (Cryo-EM) of flavivirus particles shows an icosahedral organization consisting of 30 rafts, each composed of 3 E protein dimers with an antiparallel orientation and lying flat on the virus surface ( 18 ). (asm.org)
  • Yellow fever virus (YFV) is an arthropod-borne flavivirus, infecting ~200,000 people worldwide annually and causing about 30,000 deaths. (asm.org)
  • Flavivirus encephalitis include a number of entities which characteristically involve the basal ganglia and thalami . (radiopaedia.org)
  • 3. Solomon T. Flavivirus encephalitis. (radiopaedia.org)
  • 2. The immunotherapeutic composition of claim 1, wherein the first flavivirus is Kunjin virus and the second flavivirus is West Nile virus. (freepatentsonline.com)
  • Murray Valley encephalitis (MVE) is an important mosquito-borne flavivirus infection endemic to Australia and Papua New Guinea. (histopathology-india.net)
  • West Nile virus (WNV) is a mosquito-borne flavivirus belonging to the Japanese encephalitis serocomplex, which includes St. Louis encephalitis, Murray Valley encephalitis, and Kunjin virus. (encyclopedia.com)
  • MVEV is related to Kunjin virus, which has a similar ecology, but a lower morbidity rate. (wikipedia.org)
  • The ecology and epidemiology of Kunjin virus. (ajtmh.org)
  • Low seroprevalence of Murray Valley Encephalitis and Kunjin viruses in an opportunistic serosurvey, Victoria 2011. (edu.au)
  • Objective: To assess evidence of recent and past exposure to Murray Valley encephalitis virus (MVEV) and West Nile clade Kunjin virus (KUNV) in residents of the Murray Valley, Victoria, during a period of demonstrated activity of both viruses in early 2011. (edu.au)
  • Murray Valley encephalitis (MVE) and Kunjin virus disease are endemic in the tropical parts of the Northern Territory and Western Australia, but have been absent from Central Australia since 1974. (health.gov.au)
  • Murray Valley encephalitis (MVE) and Kunjin (KUN) are mosquito-borne flaviviruses found in Australia. (health.gov.au)
  • It includes those diseases caused by alphaviruses (Barmah Forest and Ross River), flaviviruses (dengue, Murray Valley encephalitis, Kunjin, Japanese encephalitis and yellow fever) and malaria. (health.gov.au)
  • In the Australian Capital Territory, infections with Murray Valley encephalitis virus and Kunjin are combined under Murray Valley encephalitis. (worldaidsday.org.au)
  • The name of Kunjin virus derives from an Aboriginal clan living on the Mitchell River close to where the virus was first isolated in Kowanyama, northern Queensland. (wikipedia.org)
  • Non-encephalitic Kunjin virus disease can cause symptoms including acute febrile illness, headache, arthralgia, myalgia, fatigue and rash. (wikipedia.org)
  • Kunjin virus encephalitis features acute febrile meningoencephalitis. (wikipedia.org)
  • Both forms of Kunjin virus disease are milder than the diseases caused by West Nile virus and Murray Valley encephalitis virus. (wikipedia.org)
  • Kunjin virus is transmitted by mosquito vectors, especially the Culex annulirostris. (wikipedia.org)
  • The control of Kunjin virus is achieved in the same ways as other mosquito-borne diseases. (wikipedia.org)
  • There is no available vaccine against Kunjin virus. (wikipedia.org)
  • In 2005, scientists at the Queensland Institute of Medical Research and the University of Queensland found that modified Kunjin virus particles injected into mice were able to deliver a gene into the immune system targeting cancer cells. (wikipedia.org)
  • West Nile virus (WNV) circulates across Australia and was referred to historically as Kunjin virus (WNV KUN ). (biomedcentral.com)
  • Kunjin is caused by infection with the Kunjin virus, which is now considered to be a variant of West Nile virus (another potentially serious illness spread by the bite of an infected mosquito). (sa.gov.au)
  • Kunjin virus is endemic (always present) in tropical parts of Australia, in birds. (sa.gov.au)
  • Most people with Kunjin virus infection have mild or no symptoms. (sa.gov.au)
  • Kunjin virus encephalitis is similar to Murray Valley encephalitis but is usually milder. (sa.gov.au)
  • Diagnosis is made by blood tests or by detecting Kunjin virus in CSF (cerebrospinal fluid: the fluid surrounding the brain and spinal cord). (sa.gov.au)
  • Infection with Kunjin virus is thought to confer lifelong immunity. (sa.gov.au)
  • There is no specific treatment for Kunjin virus infection and no vaccine to prevent infection. (sa.gov.au)
  • There is no vaccine to prevent human infection by Kunjin virus. (sa.gov.au)
  • 3. The immunotherapeutic composition of claim 2, wherein the monoclonal antibody binds Kunjin virus E protein. (freepatentsonline.com)
  • Primary viraemia responses of herons to experimental infection with Murray Valley encephalitis, Kunjin and Japanese encephalitis viruses. (canarydatabase.org)
  • Following infection, a person has lifelong immunity to the virus. (wikipedia.org)
  • However, infection, including Murray Valley encephalitis virus (MVEV) - peak risk February to July - was considered in the differential diagnosis. (mja.com.au)
  • Hematoxylin and eosin-stained autopsy specimens from a patient with a fatal infection of Murray Valley encephalitis virus imported from Australia to Canada, 2011. (cdc.gov)
  • These findings indicate the reintroduction of these viruses into Central Australia and establishment of local cycles of infection with an ongoing risk to the local population. (health.gov.au)
  • 3,5,6 Both viruses are believed to survive in cycles of infection between birds and mosquitoes in enzootic foci in the Kimberley region of Western Australia, the Top End of the Northern Territory and possibly northern Queensland. (health.gov.au)
  • Murray Valley encephalitis (MVE) virus strain OR2 was serially passaged on Vero cells to establish a persistent infection which was maintained for over 300 days. (microbiologyresearch.org)
  • These protective and interfering effects suggest that defective interfering (DI) particles are responsible for the establishment and maintenance of the MVE virus persistent infection. (microbiologyresearch.org)
  • The genetic drift of the parental virus during the course of a long term persistent infection in vitro appears to be minimal. (microbiologyresearch.org)
  • A neutralization escape variant of Murray Valley encephalitis virus (MVE), of low neuroinvasiveness in mice and with low haemagglutination activity, had a reduced rate of replication in cultured cells during the early phase of infection compared to wild-type MVE. (microbiologyresearch.org)
  • There were 1,009 notifications of dengue virus infection locally-acquired in North Queensland and 484 notified cases resulted from overseas travel. (health.gov.au)
  • Notification rates of dengue virus infection for 2008-09, regardless of where infection was acquired, exceeded the five-year mean rate and may be attributed to increased disease activity in the Asia-Pacific region. (health.gov.au)
  • North Queensland was the site of several outbreaks of locally-acquired dengue virus infection involving all 4 serotypes. (health.gov.au)
  • Results of continuous electroencephalography (EEG) for a patient with a fatal infection of Murray Valley encephalitis virus imported from Australia to Canada, 2011. (cdc.gov)
  • This is the first confirmed case of naturally-occurring equine encephalitis attributable to Murray Valley encephalitis virus infection. (edu.au)
  • Infection may be acquired as people travel through regions with MVE virus activity, but diagnosis may be undertaken elsewhere, when travellers return home or when severe cases are transferred for medical treatment. (health.gov.au)
  • Another study, co-authored by Dr Sheik Umar Khan who subsequently succumbed to an Ebola virus infection in Sierra Leone, was published after the outbreak began. (theconversation.com)
  • A sensitive reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for rapid visual detection of Murray valley encephalitis virus (MVEV) infection . (bvsalud.org)
  • Illness ranges from asymptomatic infection (about one in 200 infections is estimated to become clinically apparent) to severe encephalitis with a high mortality and a high rate of permanent neurological sequelae in survivors (approximately 30 per cent). (netdoctor.co.uk)
  • The incubation period, from infection to developing Japanese encephalitis, is five to 15 days. (netdoctor.co.uk)
  • In collaboration with jurisdictional health authorities and the Australian Government, surveillance for Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) is conducted by the Kirby Institute for Infection and Immunity in Society (formerly the National Centre in HIV Epidemiology and Clinical Research). (abs.gov.au)
  • Previous infection with dengue virus (DENV) partially protects against JE and might also influence serum neutralising antibody titres against JEV. (bioportfolio.com)
  • IgM (indicating recent infection) against both viruses was detected in a small number of participants. (bioportfolio.com)
  • Serological evidence of infection with dengue and Zika viruses in horses on French Pacific Islands. (bioportfolio.com)
  • Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5. (bioportfolio.com)
  • Infection with the virus often causes no symptoms, but it can lead to either an encephalitic disease or a non-encephalitic disease. (wikipedia.org)
  • Infection results in activation of innate and adaptive immune responses which attempt to control infection, but may also contribute to pathology, particularly in the case of encephalitis. (biomedcentral.com)
  • After human immunodeficiency virus infection, JE may be the leading cause of viral encephalitis worldwide. (cdc.gov)
  • 2015. Zika virus infection, Philippines, 2012. (springer.com)
  • Avian models of West Nile virus (WNV) disease have become pivotal in the study of infection pathogenesis and transmission, despite the intrinsic constraints that represents this type of experimental research that needs to be conducted in biosecurity level 3 (BSL3) facilities. (mdpi.com)
  • Other arthropods, like ticks, are also susceptible to WNV infection, and the virus has been repeatedly isolated from both soft and hard ticks [ 9 ], although their role as vectors of WNV transmission is still uncertain. (mdpi.com)
  • Japanese encephalitis (JE), a mosquito-borne arboviral infection, is the leading cause of viral encephalitis in Asia (2- 4). (cdc.gov)
  • Infection leads to overt encephalitis in only 1 of 20 to 1,000 cases. (cdc.gov)
  • Past infection with the BK virus is widespread, but significant consequences of infection are uncommon, with the exception of the immune-compromised and the immunosuppressed. (lifeworkpotential.com)
  • Healthy individuals can be infected with the virus and show no signs or symptoms, due to the immune system's ability to keep the infection in check. (lifeworkpotential.com)
  • An improved understanding of the complex mechanisms regulating YFV-17D attenuation will provide insights into the key virus-host interactions that regulate host immune responses and infection outcomes as well as open novel avenues for the development of innovative vaccine strategies. (asm.org)
  • West Nile virus (WNV) causes severe central nervous system (CNS) infection primarily in humans who are immunocompromised or elderly. (asm.org)
  • Wild-type mice replicated virus extraneuronally in the draining lymph nodes and spleen during the first 4 days of infection. (asm.org)
  • Congenic mice that were genetically deficient in B cells and antibody (μMT mice) developed increased CNS viral burdens and were vulnerable to lethal infection at low doses of virus. (asm.org)
  • Experiments with related and unrelated RNA viruses have suggested that antibody may have an important protective role against WNV infection. (asm.org)
  • However, for many of these viruses the mechanism by which antibody attenuates CNS infection has not been clearly demonstrated. (asm.org)
  • In this study, we established a mouse model of infection with C57BL/6 mice that paralleled human disease: infection via a subcutaneous route resulted in a subset of mice developing encephalitis. (asm.org)
  • Infectious virus appeared in the lymph node and spleen within the first 4 days of infection and then spread concomitantly to the spinal cord and brain. (asm.org)
  • Local media are reporting an apparent case of West Nile virus infection in a horse in Northampton County, Pennsylvania . (wormsandgermsblog.com)
  • Rarely infection may progress to encephalitis (infection or inflammation of the brain). (sa.gov.au)
  • 14. An immunotherapeutic composition for treating a West Nile virus infection of an equine, said composition comprising a monoclonal antibody selected from the group consisting of mAb 3.91D and mAb 3.67G at a dosage sufficient to neutralize said West Nile virus. (freepatentsonline.com)
  • Infection is confirmed by a significant rise in antibody titre to the virus in two blood specimens taken seven to ten days apart. (histopathology-india.net)
  • Another study shows that 3.9 billion people are at risk of infection with dengue virus (DENV) in 128 countries [ 1 ]. (intechopen.com)
  • Diagnostic tests providing a proper identification of DENV infection by any of its four serotypes in symptomatic or asymptomatic cases in the population, and especially in areas that have more than one arbovirus or another micro-organism (virus, bacteria or parasite) producing similar signs and symptoms are the key aspect of any dengue research and surveillance programs [ 2 ]. (intechopen.com)
  • The Murray Valley encephalitis virus infection may produce no symptoms in some people but of those that do become ill, it is estimated that about 20% die and 50% of survivors have permanent neurological damage. (rightdiagnosis.com)
  • Mouse monoclonal antibody prepared against the envelope glycoprotein of West Nile virus (WNV) was purified from clone E58 hybridoma supernatant by protein G affinity chromatography. (atcc.org)
  • West Nile virus. (netdoctor.co.uk)
  • The company says the new assay can also detect other members of the Japanese Encephalitis virus group, of which West Nile is a member. (thefreedictionary.com)
  • De Groot and her colleagues compared the genomes of a Japanese encephalitis virus and a strain of West Nile virus that killed several people in New York in 1999. (thefreedictionary.com)
  • As an example, test results on West Nile virus detection in a panel of 340 mosquito pool samples from Greece are presented. (hindawi.com)
  • It is a subtype of West Nile virus endemic to Oceania. (wikipedia.org)
  • It is antigenically and genetically very similar to West Nile virus and in 1999 was reclassified as a subtype of WNV. (wikipedia.org)
  • Such an introduction occurred in 1999, resulting in an outbreak of West Nile (WN) encephalitis in the New York City area ( 11 ). (asm.org)
  • Zika targets the nervous and reproductive system and is supported 99 percent within the clade shared by West Nile (WNV) and St. Louis encephalitis (SLE). (infobarrel.com)
  • Yet others, including Duane Gubler, a virologist at Duke-NUS Medical School in Singapore, noted that several Zika relatives spread by Culex mosquitoes (including West Nile virus) target the nervous system which ZIKV also seems to do. (infobarrel.com)
  • Japanese encephalitis (JE) virus, belonging to West Nile (WNV) subgroup, is antigenically closely related to viruses in the same subgroup, i.e. (infobarrel.com)
  • West Nile virus (WNV) is a globally-distributed mosquito-borne virus. (biomedcentral.com)
  • Mosquito- based surveillance systems for Japanese Encephalitis and West Nile Virus, with risk assessment for West Nile Virus in Eastern Australia. (edu.au)
  • It was first isolated in 1937 from the blood of a febrile woman in the West Nile district of Uganda, hence the name of the virus [ 2 ]. (mdpi.com)
  • West Nile virus is an ecological generalist [ 3 ] with an extraordinarily complex eco-epidemiology. (mdpi.com)
  • JE virus is related antigenically to the flaviviruses of St. Louis encephalitis and Murray Valley encephalitis, and to West Nile virus (5). (cdc.gov)
  • Several reports on West Nile virus (WNV) suggest that the Asn 154-linked glycan is a virulence determinant ( 3 , 26 , 40 , 42 ). (asm.org)
  • West Nile virus (WNV), a single-stranded positive-polarity RNA virus, is the etiologic agent of West Nile encephalitis. (asm.org)
  • After being a relatively rare problem in most regions over the past few years, West Nile virus (WNV) case numbers have boomed lately, with large outbreaks in some US states. (wormsandgermsblog.com)
  • Early West Nile virus case in Pennsylvania horse? (wormsandgermsblog.com)
  • The latest update on equine infecious neurological diseases in Ontario (Eastern equine encephalitis (EEE), West Nile virus (WNV), rabies and neuropathic equine herpevirus type 1 (EHV-1)) is available from the Ontario Ministry of Agriculture, Food and Rural Affairs . (wormsandgermsblog.com)
  • The mosquito-borne diseases eastern equine encephalitis (EEE) and West Nile (WNV) continue to rear their ugly heads in the northeast as we get further into the late summer season during which they are most common. (wormsandgermsblog.com)
  • Following on the heels of the beginning of the start eastern equine encephalitis (EEE) season, warnings are going out about another mosquito-borne disease in parts of North America, West Nile virus (WNV) encephalitis. (wormsandgermsblog.com)
  • 4. The immunotherapeutic composition of claim 4 wherein the monoclonal antibody is capable of binding a conformational epitope of West Nile virus E protein. (freepatentsonline.com)
  • 5. The immunotherapeutic composition of claim 4, wherein the West Nile virus E protein epitope comprises threonine residue 332. (freepatentsonline.com)
  • 6. The immunotherapeutic composition of claim 5, wherein the West Nile virus E protein epitope further comprises an amino acid residue selected from the group consisting of Ser 306, Lys 307 and Thr 330. (freepatentsonline.com)
  • 7. The immunotherapeutic composition of claim 6, wherein the West Nile virus E protein epitope further comprises an amino acid residue selected from the group consisting of Asn 368 and Gln 391. (freepatentsonline.com)
  • PDF] Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States. (semanticscholar.org)
  • Molecular determinants of virulence of West Nile virus in North America. (semanticscholar.org)
  • West Nile virus - where did it come from and where might it go? (semanticscholar.org)
  • West Nile virus in livestock and wildlife. (semanticscholar.org)
  • Extensive nucleotide changes and deletions within the envelope glycoprotein gene of Euro-African West Nile viruses. (semanticscholar.org)
  • Indigenous wild birds of the Nile Delta as potential West Nile virus circulating reservoirs. (semanticscholar.org)
  • MVEV is a mosquito-borne virus that is maintained in a bird-mosquito-bird cycle. (wikipedia.org)
  • The scientific study of the genetics of MVEV has been facilitated by the construction and manipulation of an infectious cDNA clone of the virus. (wikipedia.org)
  • To study the genetic diversity of Murray Valley encephalitis virus (MVEV) in Australia and Papua New Guinea. (cdc.gov)
  • While clinical cases are uncommon, MVEV can cause severe encephalitis with high mortality. (edu.au)
  • JAPAN encephalitis virus (JEV) serocomplex, which also contains Murray Valley encephalitis virus (MVEV), is several antigenically related, mosquito-borne flaviviruses that are in charge of severe encephalitic disease in humans. (biotechnologysymposium.com)
  • Sporadically, MVEV spreads to central or southern parts of Australia (e.g., the Murray Valley of southeastern Australia) and causes epidemic viral encephalitis in human beings (32). (biotechnologysymposium.com)
  • The assay was further evaluated using spiked cerebrospinal fluid sample with pseudotype virus containing the NS5 gene of MVEV. (bvsalud.org)
  • The Murray Valley encephalitis virus (MVEV) was isolated during an epidemic of encephalitis in the Murray River valley in Victoria and South Australia in 1951. (histopathology-india.net)
  • There are other flaviviruses that cause viral encephalitis. (netdoctor.co.uk)
  • St Louis and Murray Valley flaviviruses. (netdoctor.co.uk)
  • Flaviviruses, such as Dengue virus (DENV) [ 2 ] and Yellow fever virus (YFV) [ 3 ], have been a common cause of devastating diseases in tropical and less developed countries, but in recent years the emergence of flaviviral zoonoses was observed worldwide. (hindawi.com)
  • Like RNA viruses in general, flaviviruses are distinguished by extensive genetic heterogeneity, which implies classification into subunits, for example, genotypes and lineages, each with distinct epidemiological or clinical significance. (hindawi.com)
  • Dengue viruses types 1 and 2, which belong to another subgroup of flaviviruses, show markedly less antigenic homology to JE virus. (infobarrel.com)
  • Flaviviruses are positive-sense RNA viruses, and many are important human pathogens. (springer.com)
  • The E protein of most flaviviruses is modified by Asn-linked glycosylation at residue 153/154 and in the case of the four dengue virus (DENV) serotypes by a second glycan at residue 67. (asm.org)
  • However, the absence of E protein glycosylation among numerous natural isolates of different flaviviruses suggests that the glycan, per se , is not critically important in the virus life cycle. (asm.org)
  • The dueling influences of infectivity and release on virus growth affected by the glycans may explain the plasticity in E protein glycosylation among the flaviviruses. (asm.org)
  • Arthropod-borne flaviviruses such as dengue virus (DENV), yellow fever virus (YFV), and Zika virus (ZIKV) are a cause of major health concerns worldwide ( 1 - 3 ). (asm.org)
  • 2. Turtle L, Griffiths MJ, Solomon T. Encephalitis caused by flaviviruses. (radiopaedia.org)
  • During his career, he has gained experience with a range of viruses, including orthomyxoviruses, flaviviruses, bunyaviruses and caliciviruses. (edu.au)
  • If the annual incidence of herpes encephalitis, probably the most common sporadic viral encephalitis, is estimated at 5 per million, then approximately 25,000 such cases occur worldwide each year (5). (cdc.gov)
  • Although sporadic cases of viral encephalitis had been noted in northern Thailand before 1969, epidemic transmission of JE was first recognized that year, when an outbreak leading to 685 cases occurred in the Chiang Mai valley. (cdc.gov)
  • The new Japanese encephalitis (IXIARO) vaccine was launched by Novartis more than three years ago, and in 2013 new guidance was given for its use in children. (netdoctor.co.uk)
  • Recommendations for use of inactivated Vero cell culture-derived Japanese encephalitis (JE) vaccine in adults and children aged [greater than or equal to] 2 months traveling to JE-endemic areas * * JE vaccine is recommended for travelers who plan to spend a month or longer in endemic areas during the JE virus transmission season. (thefreedictionary.com)
  • It was reported yesterday that Sanofi Pasteur, the Sanofi vaccines division, has introduced a Japanese encephalitis vaccine, IMOJEV, in Australia. (thefreedictionary.com)
  • JE viruses isolated from human cases in Japan in 1935 and in Beijing in 1949 provided the prototype Nakayama, Beijing and P3 strains respectively that are in principal use in vaccine production. (cdc.gov)
  • There is currently no vaccine or specific medicine for these viruses. (sercul.org.au)
  • Summary Japanese encephalitis (JE) vaccine was available in the United States from 1983 through 1987 on an investigational basis, through travel clinics in collaboration with CDC (1). (cdc.gov)
  • JE vaccine manufactured by Biken and distributed by Connaught Laboratories, Inc. (Japanese encephalitis virus vaccine, inactivated, JE-VAX), was licensed on December 10, 1992, to meet the needs of increasing numbers of U.S. residents traveling to Asia and to accommodate the needs of the U.S. military. (cdc.gov)
  • Travelers to Papua New Guinea, remote northwestern Australia, or southeastern Australia are at risk for being infected with Murray Valley encephalitis. (cdc.gov)
  • A mosquito-borne virus that occurs in northern Australia and Papua New Guinea and can cause encephalitis. (rightdiagnosis.com)
  • Their ignoring by researchers has led to failures in the design of vaccines against HIV/AIDS, dengue fever, influenza, malaria, hemorrhagic fever and encephalitis. (supotnitskiy.ru)
  • Two experiments were conducted to determine if Japanese B encephalitis virus could interfere with the transmission of Murray Valley encephalitis virus by C. tritaeniorhynchus infected sequentially. (ajtmh.org)
  • MAbs to epitopes in one domain neutralized virus, were specific for MVE and Japanese encephalitis virus, and reacted with epitopes resistant to reduction. (edu.au)
  • What is Japanese encephalitis? (netdoctor.co.uk)
  • The Japanese encephalitis virus belongs to the Flaviviridae family. (netdoctor.co.uk)
  • It's thought that only in 100 adults who come into contact with Japanese encephalitis actually develop any visible signs of it. (netdoctor.co.uk)
  • Like Japanese encephalitis, these viruses often only produce mild general symptoms - similar to mild influenza . (netdoctor.co.uk)
  • How does Japanese encephalitis spread? (netdoctor.co.uk)
  • Japanese encephalitis virus is passed on by the bite of an infected mosquito that has previously sucked blood from an infected animal or person. (netdoctor.co.uk)
  • The Japanese encephalitis virus, in particular, is also able to replicate itself in pigs and birds. (netdoctor.co.uk)
  • Where does Japanese encephalitis occur and how many people are affected? (netdoctor.co.uk)
  • In the UK, rare cases of Japanese encephalitis are reported in travellers from abroad. (netdoctor.co.uk)
  • But by far, the majority of cases of Japanese encephalitis do not have either brain symptoms or serious consequences. (netdoctor.co.uk)
  • It causes a fulminating viremia resembling Japanese encephalitis (ENCEPHALITIS, JAPANESE). (bioportfolio.com)
  • Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: A case for further catch up campaigns? (bioportfolio.com)
  • Dengue virus is an under-recognised causative agent of acute encephalitis syndrome (AES): Results from a four year AES surveillance study of Japanese encephalitis in selected states of IndiaDengue virus is an under-recognised causative. (bioportfolio.com)
  • Changing Geographic Distribution of Japanese Encephalitis Virus Genotypes, 1935-2017. (bioportfolio.com)
  • Japanese encephalitis virus (JEV) causes central nervous system neuronal injury and inflammation. (bioportfolio.com)
  • Comprehensive mapping antigenic epitopes of NS1 protein of Japanese encephalitis virus with monoclonal antibodies. (thefreedictionary.com)
  • In our study it can be seen that scrub typhus was the most important infective cause of AES, second only to Japanese Encephalitis in our region. (thefreedictionary.com)
  • Sophie is suffering from a severe form of Japanese encephalitis , which is most common in rural areas throughout South East Asia, the Pacific islands and the Far East, but is very rare in travellers. (thefreedictionary.com)
  • Doctors are referring all patients to NBMCH to get the Japanese encephalitis test done. (thefreedictionary.com)
  • Particularly, from 7th July itself, and they are coming now, till now 83 cases out of 344 have been detected as Japanese encephalitis and other are due to some other causes," said Satpathy. (thefreedictionary.com)
  • It is an arbovirus which is transmitted by mosquitoes and is part of the Japanese encephalitis serological complex. (wikipedia.org)
  • Others, such as Japanese encephalitis and dengue fever, are endemic and are expanding in certain parts of the world. (asm.org)
  • I created another cladogram, shown next (based on Dr. Fiona Hunter's slide) which includes Japanese encephalitis (JE). (infobarrel.com)
  • Japanese encephalitis (JE) is a mosquito-borne arboviral disease of major public health importance in Asia. (cdc.gov)
  • The virus initially was called Japanese B encephalitis (the modifying B has fallen into disuse) to distinguish the agent from the etiology of Von Economo's type A encephalitis, which had different epidemiologic characteristics. (cdc.gov)
  • Japanese encephalitis has appeared in the Torres Strait Islands and threatens mainland Australia. (prohealth.com)
  • The virus was isolated from human samples in 1951 during an epidemic in the Murray Valley, Australia. (wikipedia.org)
  • The last national epidemic of MVE encephalitis occurred in 1974, 2 beginning in the Murray Valley region of south-eastern Australia. (health.gov.au)
  • Studies were conducted with Culex tritaeniorhynchus and Culex pipiens quinquefasciatus to ascertain the behavior of Murray Valley encephalitis virus in these two species of mosquitoes and to determine if they could transmit this virus. (ajtmh.org)
  • Virus multiplication was demonstrated in both species of mosquitoes following ingestion of blood from viremic chicks. (ajtmh.org)
  • The multiplication of virus in mosquitoes followed an "eclipse" period during which it could not be detected. (ajtmh.org)
  • Culex annulirostris is the major vector of MVE virus, although other mosquitoes, such as Aedes normanensis may also be involved. (health.gov.au)
  • The Division of Vector-Borne Diseases (DVBD) strives to protect the nation from viruses and bacteria spread by mosquitoes, ticks, or fleas. (cdc.gov)
  • The virus was first isolated from Culex annulirostris mosquitoes in Australia in 1960. (wikipedia.org)
  • The virus has been isolated in mosquitoes in South East Asia but in humans, only in Australia. (wikipedia.org)
  • The principal reservoirs of SLE include wild birds and domestic fowl, and the virus is transmitted to humans by mosquitoes, namely Culex tarsalis, Culex quinquefasciatus, and Culex pipiens . (infobarrel.com)
  • The mosquito-borne mode of JE transmission was elucidated with the isolation of JE virus from Culex tritaeniorhynchus mosquitoes in 1938 and in field studies that established the role of aquatic birds and pigs in the viral enzootic cycle. (cdc.gov)
  • Not all infected hosts transmit the virus, but only those in which the virus replicates efficiently enough to reach viremias sufficiently high to infect mosquitoes through blood feeding. (mdpi.com)
  • The virus is transmitted in an enzootic cycle among mosquitoes and vertebrate- amplifying hosts, chiefly domestic pigs and Ardeid (wading) birds (2). (cdc.gov)
  • The virus circulates among rodents and vector mosquitoes and sometimes infects humans, causing a febrile illness with occasional neurological manifestations. (lifeworkpotential.com)
  • Mosquitoes were responsible for more than 35,000 cases of Ross River virus during 1991-1997. (prohealth.com)
  • Although the weather in Southwestern Ontario seems quite confused lately regarding whether it wants to be winter or spring, at least we're still a few months off from having to worry about mosquitoes and the viruses they carry once again. (wormsandgermsblog.com)
  • The experiments showed that ~26°C (80°F) is the optimal temperature for mosquitoes to spread the Ross River virus. (elifesciences.org)
  • Although the arbovirus is endemic to Northern Australia, it has occasionally spread to the southern states during times of heavy rainfall during the summer monsoon season via seasonal flooding of the Murray-Darling River system. (wikipedia.org)
  • 2009. Molecular characterization of Murray Valley encephalitis virus, in Ryan, P. and Aaskov, J. and Russell, R. (ed), 10th Arbovirus Research in Australia Symposium, Sep 15 2008, Coffs Harbour, New South Australia: The Queensland Institute of Medical Reseach. (edu.au)
  • Murray Valley virus - a group B arbovirus that causes Murray Valley encephalitis. (thefreedictionary.com)
  • In this chapter, the most used laboratory tests in an arbovirus study focused on diagnosis and research of dengue virus (DENV) will be assessed, some comparisons will be carried out with other laboratory tests, its features, advantages and disadvantages, and cautions need to be considered during the process. (intechopen.com)
  • The system was complemented by other surveillance systems, which provided information on various diseases, including four that are not reported to the National Notifiable Diseases Surveillance System (NNDSS), human immunodeficiency virus (HIV), acquired immune deficiency syndrome (AIDS) and the classical and variant forms of Creutzfeldt-Jakob disease (CJD). (health.gov.au)
  • In collaboration with the state and territory health authorities and the Australian Government, surveillance for human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) is conducted by the National Centre in HIV Epidemiology and Clinical Research. (abs.gov.au)
  • Recently, Zika virus (ZIKV) also expanded into Southern America, with reports of detection in Europe and USA [ 8 ]. (hindawi.com)
  • Since May 2016, I have been researching the Zika virus and have compiled unpublicized facts on my blog post: Why We Must Demand the CDC and Health Canada Enact Level 3 (Avoid Nonessential Travel). (infobarrel.com)
  • The Zika virus (ZIKV) is not a hemorrhagic disease , even though the CDC, WHO, and mainstream media only compare it to dengue (DENV) and yellow fever (YF). (infobarrel.com)
  • Phylogenetic analysis of the NS5 gene of Zika virus. (springer.com)
  • Zika virus produces noncoding RNAs using a multiseudoknot structure that confounds a cellular exonuclease. (springer.com)
  • Comparison of the structure with that of dengue virus type 4 NS2B-NS3 reveals a relative orientation of the two domains that is radically different between the two structures. (rcsb.org)
  • This family also includes the dengue virus and yellow fever virus. (netdoctor.co.uk)
  • Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis. (springer.com)
  • Long-range RNA-RNA interactions circularize the dengue virus genome. (springer.com)
  • Structural and functional analysis of dengue virus RNA. (springer.com)
  • Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography. (springer.com)
  • The RNA helicase, nucleotide 5′-triphosphatase, and RNA 5′-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core. (springer.com)
  • Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase. (springer.com)
  • Furthermore, loss of the Asn 153-linked glycan observed during mosquito cell adaptation of dengue virus (DENV) suggests that its absence is associated with a selective growth advantage in some cell types, which may be related to an altered fusion phenotype ( 15 , 23 ). (asm.org)
  • TDV comprised of 1 molecularly characterized, attenuated dengue virus strain and 3 chimeric dengue virus strains: TDV-1, TDV-2, TDV-3 and TDV-4 containing not less than 3.3, 2.7, 4.0, and 4.5 log10 plaque forming units (PFU) respectively. (clinicaltrials.gov)
  • Therefore, determining whether a person has, had, or is infected with dengue virus is of great importance. (intechopen.com)
  • St. Louis encephalitis virus (SLE) belongs to the family Flaviviridae (group B arboviruses). (infobarrel.com)
  • MVE virus is enzootic in the Northern Territory and cases of Murray Valley encephalitis have been reported in a number of years since the 1974 outbreak. (health.gov.au)
  • The regional location of acquisition of cases of Murray Valley encephalitis notified by the Northern Territory is shown in Table 3. (health.gov.au)
  • Forty-one cases of Murray Valley encephalitis acquired in Western Australia have been notified since the 1974 outbreak 2,8,12,32 (regional location, of where infections were acquired are given in Table 4). (health.gov.au)
  • As well as a recent case in Mt Isa in 2001, 4 cases of Murray Valley encephalitis have been reported in Queensland since the 1974 outbreak, including 2 in 1991 33 (only 1 of which was a confirmed case), one in 1994 34 and 1 in 1997 (personal communication, J Hanna). (health.gov.au)
  • Cases of Murray Valley encephalitis have occurred in 14 of the past 20 years in northern Australia. (prohealth.com)
  • Murray Valley encephalitis - a severe encephalitis with high mortality. (thefreedictionary.com)
  • Encephalitis usually is severe, resulting in a fatal outcome in 25% of cases and residual neuropsychiatric sequelae in 30% of cases (2,6). (cdc.gov)
  • Although typical manifestation of WNV is asymptomatical, the virus can cross the blood-brain barrier and cause severe illness, paralysis, and even death in humans and animals. (encyclopedia.com)
  • The virus was ecologically characterized in Egypt during the 1950s and later linked to severe human meningoencephalitis in elderly patients during a 1957 outbreak in Israel. (encyclopedia.com)
  • There are no vaccines or medicines that prevent Murray Valley encephalitis. (cdc.gov)
  • Only a few mosquito-borne viruses can be prevented with vaccines. (cdc.gov)
  • In this study we have examined epitopes recognized by 14 monoclonal antibodies (MAbs) produced to the envelope (E) and non-structural (NS1) proteins of Murray Valley encephalitis virus (MVE). (edu.au)
  • Arthropod-borne virus antibodies in sera of residents of Kainji Lake Basin, Nigeria 1980. (springer.com)
  • The E protein covers most of the virion surface and contains receptor-binding sites, the fusion peptide, and the majority of epitopes recognized by antibodies against the virus particle. (asm.org)
  • Identification of monoclonal antibodies capable of differentiating antigenic varieties of eastern equine encephalitis viruses. (semanticscholar.org)
  • The final test configuration utilized group-reactive MAbs eastern equine encephalitis virus 1A4B-6, dengue 2 virus 4G2, and La Crosse encephalitis virus 10G5.4 to capture the specific inactivated viral antigens. (asm.org)
  • Three other encephalitis viruses belong to the Alphavirus genus and are also transmitted by mosquito bite. (netdoctor.co.uk)
  • 1 Human infections are usually asymptomatic, though a small percentage develop clinical disease manifesting as febrile illness with headache, as polyarthralgic illness or as encephalitis. (health.gov.au)
  • This action preceded 4 notifications of Murray Valley encephalitis infections, 2 (fatal) cases acquired in the Northern Territory and two in Western Australia. (health.gov.au)
  • From 1996 onwards the latter included infections with MVE, KUN, JE, KOK and STR viruses. (health.gov.au)
  • Neuroviral Infections: RNA Viruses and Retroviruses presents an up-to-date overview of the general principles of infections and major neuroviral infections caused by RNA viruses and retroviruses. (routledge.com)
  • Rapid virus identification and quantification are crucial for accurate diagnosis of ongoing infections, treatment selection, and follow-up, as well as for selection and timely introduction of control measures in outbreaks scenarios. (hindawi.com)
  • Michael is interested in RNA virus replication and the innate immune response to virus infections. (edu.au)
  • The U.S. Centers for Disease Control and Prevention considers many diseases caused by arthropod-borne viruses (arboviruses) to be emerging or reemerging. (asm.org)
  • The start points of the various Murray Valley encephalitis virus-coded proteins have been assigned on the basis of this homology and a consistent set of potential proteolytic cleavage sites identified, the sequences of which are similar in Murray Valley encephalitis and yellow fever. (utmb.edu)
  • The genome organization of Murray Valley encephalitis and yellow fever appears to be identical and the sizes of the predicted virus-coded proteins similar between the two viruses. (utmb.edu)
  • Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH. (springer.com)
  • Enzymatic defects of the nsP2 proteins of Semliki Forest virus temperature-sensitive mutants. (springer.com)
  • Ongoing molecular virology research focuses on the rabbit haemorrhagic fever virus (RHDV), a highly pathogenic calicivirus that is used to control the feral rabbit population in Australia, and on interferon-induced antiviral resistance proteins in sheep and other production animals. (edu.au)
  • previously known as Australian encephalitis or Australian X disease). (wikipedia.org)
  • Australian encephalitis in Western Australia, 1978-1991. (ajtmh.org)
  • No Murray Valley encephalitis cases have ever been reported from the Australian Capital Territory or Tasmania. (health.gov.au)
  • Perhaps the same virus has been isolated earlier during epidemics of encephalitis in 1917-1918, when it went under the name of Australian X disease. (histopathology-india.net)
  • Instances of Murray Valley encephalitis are more prevalent in kids or site visitors in regions of endemic disease than in adult occupants, who've preexisting immunity (7, 42, 46). (biotechnologysymposium.com)
  • In China, few specific data are available, but the virus was isolated from a human case in 1940 and the inference of long standing endemic transmission in eastern China is supported by early seroprevalence studies yielding rates exceeding 85% (10). (cdc.gov)
  • A diagnosis of the disease should be considered in any patient who presents with encephalitis or central nervous system symptoms and who has been in the endemic area within the incubation period of the disease, (usually between November and July). (histopathology-india.net)
  • Eventually the virus attacks the cells of the central nervous system, causing the typical symptoms of the disease to appear. (netdoctor.co.uk)
  • More recently, he became involved in the characterization of RNA virus polymerases, the development and field testing of immunocontraceptive vaccinations, and the analysis of food-health relationships such as the effects of fructose consumption. (edu.au)
  • Despite its regional distribution in Asia, with more than 3 billion people and 60% of the world's population, regional morbidity from JE may exceed worldwide morbidity from herpes encephalitis. (cdc.gov)
  • This article published in Communicable Diseases Intelligence Volume 26, No 1, March 2002 contains a report on 5 laboratory-confirmed cases of encephalitis which occurred over a short period in the normally dry inland region of Central Australia in 2000. (health.gov.au)
  • The major mosquito-borne diseases in Australia are Ross River virus and the much rarer, though potentially fatal, Murray Valley encephalitis. (abc.net.au)
  • Some of these diseases can be very unpredictable, such as Venezuelan equine encephalitis (VEE), which may emerge in a cyclical fashion and cause widespread disease ( 16 ). (asm.org)
  • Has been isolated from patients with various neoplastic and degenerative diseases such as myasthenia gravis, multiple sclerosis, thyroiditis de Quervain, and Graves' disease but the role of the virus is unclear. (lifeworkpotential.com)
  • Antigenic structure of the Murray Valley encephalitis virus E glycoprotein. (semanticscholar.org)
  • Amino acid sequence homology between the Murray Valley encephalitis and yellow fever (Rice et al. (utmb.edu)
  • NS3 is a hydrophilic non-structural protein that shows 55% amino acid sequence similarity between Murray Valley encephalitis and yellow fever over the region sequenced and is probably involved in RNA replication. (utmb.edu)
  • NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies. (springer.com)
  • Total antibody seroprevalence for both viruses was higher in residents born before 1974. (edu.au)
  • South Australia, New South Wales and Victoria have not recorded a case of Murray Valley encephalitis acquired within the Murray Valley region, since 1974. (health.gov.au)
  • In the last two decades, hyperendemic JE transmission has spread within Thailand and in 1974, the first of several epidemics was recorded in an adjacent area of the Chiang Mai valley in Burma. (cdc.gov)
  • Two scientific studies published in 1986, using samples collected in 1973 and 1981-2 , had already reported finding haemorrhagic fever viruses, including Ebola virus, in the forests of Liberia. (theconversation.com)
  • The rate of multiplication was similar in both species and the virus increased to approximately the same titer in each, although a higher percentage of C. tritaeniorhynchus became infected. (ajtmh.org)
  • Specimens of both species of mosquito could transmit the virus after being held for extended periods of time which indicated the possibility that, once infected, they were capable of transmitting the virus for the duration of their lives. (ajtmh.org)
  • Murray Valley encephalitis (MVE) virus was isolated in 8 of the 13 years of the study from seven mosquito species, but more than 90% of the isolates were from Cx. (ajtmh.org)
  • This was meant to apply even to members of the Zaire ebolavirus species (an Ebola virus), one of which now ravages West Africa. (theconversation.com)
  • Note, Ebola virus is the name of the Zaire species, while ebolavirus refers to all species). (theconversation.com)
  • This is called "host competence" and is a characteristic of each host species in a specific host-virus-vector system. (mdpi.com)
  • In late summer 1999, an outbreak of human encephalitis occurred in the northeastern United States that was concurrent with extensive mortality in crows (Corvus species) as well as the deaths of several exotic birds at a zoological park in the same area. (semanticscholar.org)
  • The virus has also been identified in more than 250 bird species in the United States, including blue jays, ravens, magpies, sparrows, and starlings. (encyclopedia.com)
  • the species can carry Murray Valley encephalitis virus in laboratory studies but its potential as a vector of importance is unknown. (edu.au)
  • A Murray Valley encephalitis virus (MVE) field isolate of high neuroinvasiveness (BH3479) and a neutralization escape variant of low neuroinvasiveness (BHv1) selected from BH3479 (which differ by a single amino acid at residue 277 in the envelope glycoprotein) were examined for their distribution in the tissues of weanling Swiss mice at various times after footpad inoculation. (nih.gov)
  • EPIDEMIOLOGY: The MVE virus is present in Australia and New Guinea. (msdsonline.com)
  • Epizootic activity of Murray Valley encephalitis virus in an Aboriginal community in the southeast Kimberley region of Western Australia: results of cross-sectional and longitudinal serologic studies. (ajtmh.org)
  • Murray Valley encephalitis virus surveillance and control initiatives in Australia. (ajtmh.org)
  • In 2000, 5 laboratory-confirmed cases of encephalitis occurred over a short period in the normally dry inland region of Central Australia. (health.gov.au)
  • Eventually 5 cases of MVE and KUN encephalitis were diagnosed in Central Australia. (health.gov.au)
  • Mackenzie, JS , Lindsay, MD & Broom, AK 2000, ' Effect of climate and weather on the transmission of Ross River and Murray Valley encephalitis viruses ', Microbiology Australia , vol. 21, no. 2, pp. 20-24. (edu.au)
  • In 2011, a more virulent form of the virus emerged during an outbreak of equine arboviral disease in Australia. (biomedcentral.com)
  • Knowing how repellents work is particularly important as there are around 5,000 cases of disease caused by the mosquito-borne Ross River virus every year in Australia. (phys.org)
  • We built a mechanistic model for the thermal response of Ross River virus, an important mosquito-borne pathogen in Australia, Pacific Islands, and potentially at risk of emerging worldwide. (elifesciences.org)
  • Climate change could affect the Ross River virus, the most common mosquito-borne disease in Australia. (elifesciences.org)
  • Currently, the virus spreads year-round in tropical, northern Australia and seasonally in temperate, southern Australia. (elifesciences.org)
  • Because northern Australia is already near the optimal temperature for mosquitos to spread the Ross River virus, any climate warming should decrease transmission there. (elifesciences.org)
  • Cerebrospinal fluid (CSF) white cell count was 287 × 10 6 /L with 90% mononuclear cells, CSF protein elevated at 1.49 g/L (normal range [NR], 0.15-0.45 g/L), and CSF glucose 4.5 mmol/L (NR, 2.7-4.2 mmol/L). The most likely diagnosis was thought to be encephalitis associated with systemic lupus erythematosus, and she initially received intravenous immunoglobulin and intravenous methylprednisolone 1 g daily. (mja.com.au)
  • Mutations, which compensated for the defect in virus morphogenesis associated with ablation of the Asn 67-linked glycan in mammalian cells but interestingly not in mosquito cells, were identified at the glycosylation acceptor motif and a second site in E protein domain II. (asm.org)
  • They are Western (WEE), Eastern (EEE) and Venezuelan (VEE) equine encephalitis. (netdoctor.co.uk)
  • One of the physiological functions of the Asn 67-linked glycan may be its involvement in virus attachment to the C-type lectin DC-SIGN, expressed on dendritic cells and a subset of macrophages ( 34 , 35 ), thus conferring virus tropism to monocyte/macrophage-derived cells thought to play a role in DENV pathogenesis ( 45 ). (asm.org)
  • However, results from this study suggest that DI particles of MVE virus differ from other studied systems in that they are able to affect only moderately the yield of infectious wild-type virus. (microbiologyresearch.org)
  • Transmission of ebolaviruses between humans is by direct contact in which the broken skin or exposed mucous membrane (mouth, eyelids, genital tract) of susceptible humans is exposed to an infectious dose of Ebola virus-laden fluid (blood, vomit, faeces, sweat, saliva and semen) from a patient showing signs of the disease. (theconversation.com)
  • Names used for viruses should be those approved by the International Committee on Taxonomy of Viruses (ICTV) and reported on the ICTV Virus Taxonomy website . (asm.org)
  • however, its diagnosis is difficult due to the existence of many viruses, bacteria, and parasites producing the same clinical presentation, being present in the same geographical area and even producing coinfections. (intechopen.com)
  • Humans develop a febrile illness, with a subset of cases progressing to a meningitis or encephalitis syndrome ( 24 ). (asm.org)
  • Partial nucleotide sequence of the Murray Valley encephalitis virus genome. (utmb.edu)
  • The sequence of 5400 bases corresponding to the 5′-terminal half of the Murray Valley encephalitis virus genome has been determined. (utmb.edu)
  • Laboratory tests are based on the detection of the virus, part of its genome or structure, or specific result from an infected person or animal as immune response. (intechopen.com)
  • COMMUNICABILITY: The virus is not directly transmitted from person-to-person and most arboviruses produce low levels of viraemia that are very hard to detect(3,9,10). (msdsonline.com)
  • We have passaged the prototype strain of Murray Valley encephalitis virus in SW13 (human) cells, sequenced the E and M genes, and examined the virulence of the passaged virus for 21-day-old mice following intracranial and intraperitoneal inoculation. (nih.gov)
  • Had this population been prepared, perhaps more personal protective equipment and bleach would have been ready to go, and the rapid transmission of the West African Ebola virus outbreak might have been contained. (theconversation.com)
  • Barmah Forest virus is increasing nationwide, and unidentified bunyaviruses suspected of causing illness have been isolated. (prohealth.com)
  • When the insect feeds on another animal or human, the virus can be transmitted through the bite and cause serious illness. (encyclopedia.com)