A form of RHABDOMYOSARCOMA arising primarily in the head and neck, especially the orbit, of children below the age of 10. The cells are smaller than those of other rhabdomyosarcomas and are of two basic cell types: spindle cells and round cells. This cancer is highly sensitive to chemotherapy and has a high cure rate with multi-modality therapy. (From Holland et al., Cancer Medicine, 3d ed, p2188)
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
A form of RHABDOMYOSARCOMA occurring mainly in adolescents and young adults, affecting muscles of the extremities, trunk, orbital region, etc. It is extremely malignant, metastasizing widely at an early stage. Few cures have been achieved and the prognosis is poor. "Alveolar" refers to its microscopic appearance simulating the cells of the respiratory alveolus. (Holland et al., Cancer Medicine, 3d ed, p2188)
A sarcoma characterized by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (From Segen, Dictionary of Modern Medicine, 1992)
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.
A malignant neoplasm of the lung composed chiefly or entirely of immature undifferentiated cells (i.e., blast forms) with little or virtually no stroma. (From Stedman, 25th ed)
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)
Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
The malignant stem cells of TERATOCARCINOMAS, which resemble pluripotent stem cells of the BLASTOCYST INNER CELL MASS. The EC cells can be grown in vitro, and experimentally induced to differentiate. They are used as a model system for studying early embryonic cell differentiation.
Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
The profession of writing. Also the identity of the writer as the creator of a literary production.
Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Intentional falsification of scientific data by presentation of fraudulent or incomplete or uncorroborated findings as scientific fact.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)
Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)
A light-sensitive neuroendocrine organ attached to the roof of the THIRD VENTRICLE of the brain. The pineal gland secretes MELATONIN, other BIOGENIC AMINES and NEUROPEPTIDES.
A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)
A syndrome of multiple defects characterized primarily by umbilical hernia (HERNIA, UMBILICAL); MACROGLOSSIA; and GIGANTISM; and secondarily by visceromegaly; HYPOGLYCEMIA; and ear abnormalities.
A family of the order Rodentia containing 250 genera including the two genera Mus (MICE) and Rattus (RATS), from which the laboratory inbred strains are developed. The fifteen subfamilies are SIGMODONTINAE (New World mice and rats), CRICETINAE, Spalacinae, Myospalacinae, Lophiomyinae, ARVICOLINAE, Platacanthomyinae, Nesomyinae, Otomyinae, Rhizomyinae, GERBILLINAE, Dendromurinae, Cricetomyinae, MURINAE (Old World mice and rats), and Hydromyinae.
Adherence of cells to surfaces or to other cells.
Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The reduction or regulation of the population of noxious, destructive, or dangerous rodents through chemical, biological, or other means.
Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
A rare tumor of the female genital tract, most often the ovary, formerly considered to be derived from mesonephric rests. Two varieties are recognized: (1) clear cell carcinoma, so called because of its histologic resemblance to renal cell carcinoma, and now considered to be of muellerian duct derivation and (2) an embryonal tumor (called also ENDODERMAL SINUS TUMOR and yolk sac tumor), occurring chiefly in children. The latter variety may also arise in the testis. (Dorland, 27th ed)
A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.
The first of four extra-embryonic membranes to form during EMBRYOGENESIS. In REPTILES and BIRDS, it arises from endoderm and mesoderm to incorporate the EGG YOLK into the DIGESTIVE TRACT for nourishing the embryo. In placental MAMMALS, its nutritional function is vestigial; however, it is the source of INTESTINAL MUCOSA; BLOOD CELLS; and GERM CELLS. It is sometimes called the vitelline sac, which should not be confused with the VITELLINE MEMBRANE of the egg.
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
A plant genus in the family ROSACEAE and order Rosales. This should not be confused with the genus RHODIOLA which is sometimes called roseroot.
A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).
The study of the structure, behavior, growth, reproduction, and pathology of cells; and the function and chemistry of cellular components.
Societies whose membership is limited to scientists.
A republic in southern Africa east of ZAMBIA and MOZAMBIQUE. Its capital is Lilongwe. It was formerly called Nyasaland.
Straube W (1989). "[Early embryonal signals]". Zentralblatt für Gynäkologie. 111 (10): 629-33. PMID 2665388. Smart YC, Roberts ...
subtype of embryonal rhabdomyosarcoma [9][16][17][18][22][27][28] Leimyosarcoma no localized tumor of leukemic cells [18][29] ...
Because embryonal carcinoma can differentiate into cells of all three germ layers, P19 cells can also differentiate into those ... When embryonal carcinoma cells are cultured at high density, they start to differentiate. By aggregating the cells into an ... van der Heyden, MA; Defize, LH (2003-05-01). "Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us ... For developmental biologists, embryonal carcinoma, which is derived from teratocarcinoma, is a good object for developmental ...
The embryonal whorls are smooth. The others contain from seven to ten short longitudinal ribs forming a tuberculated shoulder. ...
"Embryonal risks in gestational diabetes mellitus". Early Human Development. 79 (1): 59-63. doi:10.1016/j.earlhumdev.2004.04. ...
Gerard, Smith, Austin (1986). "Genetic analysis of embryonal carcinoma cells". hdl:1842/20194. Cite journal requires ,journal ...
"Mouse models of CNS embryonal tumors". Brain Tumor Pathology. 26 (2): 43-50. doi:10.1007/s10014-009-0253-0. PMID 19856214.. ...
... embryonal carcinoma, teratocarcinoma, and choriocarcinoma; clinical and microscopical analysis (20 min; color). PMF 5316 (1957 ...
embryonal carcinoma, ICD-O 9070/3). *mieszany rak gruczołowy (ang. mixed adenocarcinoma, ICD-O 8255/3) ...
... or botryoid sarcoma[1] or botryoid rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma, that can be ... Hilgers R (1975). "Pelvic exenteration for vaginal embryonal rhabdomyosarcoma: a review". Obstet Gynecol. 45 (2): 175-80. PMID ... Reynolds E, Logani S, Moller K, Horowitz I (2006). "Embryonal rhabdomyosarcoma of the uterus in a postmenopausal woman. Case ... Piver M, Rose P (1988). "Long-term follow-up and complications of infants with vulvovaginal embryonal rhabdomyosarcoma treated ...
Moniaga NC, Randall LM (February 2011). "Malignant mixed ovarian germ cell tumor with embryonal component". Journal of ... yolk sac tumor and embryonal carcinoma harboring an EGFR mutation: a case report". OncoTargets and Therapy. 11: 6853-6862. doi: ... yolk sac tumor and embryonal carcinoma harboring an EGFR mutation: a case report". OncoTargets and Therapy. 11: 6853-6862. doi: ...
"Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1". Ophthalmic Plast Reconstr Surg. 23 (2): 147-8 ...
... s of embryonal origin are most often found in babies at birth, in young children, and, since the advent of ultrasound ... Embryonal teratomas most commonly occur in the sacrococcygeal region; sacrococcygeal teratoma is the single most common tumor ... All tumors of this class are the result of abnormal development of pluripotent cells: germ cells and embryonal cells. Teratomas ... Of 641 children with pure teratoma, nine developed TMT: five carcinoma, two glioma, and two embryonal carcinoma (here, these ...
Schopperle WM, Kershaw DB, DeWolf WC (Jan 2003). "Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin". ...
Boulter CA, Wagner EF (March 1988). "The effects of v-src expression on the differentiation of embryonal carcinoma cells". ... Przyborski SA (2001). "Isolation of human embryonal carcinoma stem cells by immunomagnetic sorting". Stem Cells. 19 (6): 500-4 ... "The small heat shock protein hsp25 is accumulated in P19 embryonal carcinoma cells and embryonic stem cells of line BLC6 during ... "Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal ...
Zhang L, Yoshida K, Liu J, Rosenberg RD (1999). "Anticoagulant heparan sulfate precursor structures in F9 embryonal carcinoma ...
P-glycoprotein, a transporter, exists already in the embryonal endothelium. Measurement of brain uptake of various blood-borne ...
Piccolo was a running back for the Bears from 1966 until his untimely death from embryonal cell carcinoma on June 16, 1970, at ... When Piccolo died in 1970, embryonal cell carcinoma was 100% fatal. With advances in medicine over the years, more than 50% of ... He was then diagnosed with embryonal cell carcinoma, an aggressive form of testicular cancer that had already spread to his ...
2003), "Resemblance to embryonal tissue", Holland-Frei Cancer Medicine (6th ed.), Hamilton, Ontario, Canada: BC Decker, ISBN 1- ... while embryonal and alveolar morphology had equal distribution (3/6). Patients with the alveolar subtype harbored the ... FOXO1 fusion with PAX3 or PAX7 in alveolar expression Chromosome amplification of 6p21.32-p21.2 and 6p11.2 in embryonal RMS ...
2003), "Resemblance to embryonal tissue", Holland-Frei Cancer Medicine (6th ed.), Hamilton, Ontario, Canada: BC Decker, ISBN 1- ... A rhabdomyoblast found histologically is considered diagnostic for embryonal, alveolar, and pleomorphic rhabdomyosarcomas. ...
Concurrent cyclophosphamide and craniospinal radiotherapy for pediatric high-risk embryonal brain tumors. 10(J), Retrieved from ...
Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 2002; 415:436-442. Cho YJ, ...
Tiffin N, Williams RD, Shipley J, Pritchard-Jones K (July 2003). "PAX7 expression in embryonal rhabdomyosarcoma suggests an ... A link to the metastatic potential of embryonal rhabdomyosarcoma and cutaneous malignant melanoma?". Histology and ...
Teratogenesis Cyanazine may cause malformations in the embryonal development of some species. In Silurana tropicalis, exposure ...
The most common specific subtypes are intratubular embryonal carcinoma and intratubular seminoma. GCNIS is seen in the ...
History of IPB Embryonal Step (1941-1963) History of IPB Growth phase. History of IPB - Rectors retrieved September 1, 2013 " ...
Yang Z, Sui Y, Xiong S, Liour SS, Phillips AC, Ko L (2007). "Switched alternative splicing of oncogene CoAA during embryonal ...
Lin TY, Chu C, Chiu CH (October 2002). "Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells ...
Embryonal and larval development of F1 generation of green frogs different combinations. Acta Zool. Cracov. 12, 7: 123-160. ...
Jones-Villeneuve EM, McBurney MW, Rogers KA, Kalnins VI (1982). "Retinoic acid induces embryonal carcinoma cells to ...
Definition of embryonal carcinoma. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and ... embryonal carcinoma. Definition: a malignant neoplasm of the testis or ovary, composed of anaplastic cells with indistinct ...
Rhabdomyosarcoma has two major histologic subtypes, embryonal and alveolar, each with distinct clinical, molecular, and genetic ... Genomic analysis shows that embryonal tumors have mo … ... Genomic analysis shows that embryonal tumors have more ... Targeting oxidative stress in embryonal rhabdomyosarcoma Cancer Cell. 2013 Dec 9;24(6):710-24. doi: 10.1016/j.ccr.2013.11.002. ... Mutations in the RAS/NF1 pathway are significantly associated with intermediate- and high-risk embryonal rhabdomyosarcomas ( ...
Males with pure embryonal carcinoma tend to have a normal amount of the protein alpha-fetoprotein in the fluid component of ... Embryonal carcinoma is a relatively uncommon type of germ cell tumour that occurs in the ovaries and testes. The presenting ... The clinical features associated with metastasising embryonal carcinoma may include low back pain, dyspnoea, cough, haemoptysis ...
Embryonal rhabdomyosarcoma (ERMS) is a rare histological form of cancer of connective tissue wherein the mesenchymally-derived ... Masola V, Maran C, Tassone E, Zin A, Rosolen A, Onisto M (2009). "Heparanase activity in alveolar and embryonal ... "A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with ...
Embryonal carcinoma is a germ cell tumor characterized by primitive epithelial cells with marked pleomorphism and various ... Intratubular embryonal carcinoma is commonly associated with embryonal carcinoma (see the image below). Intratubular embryonal ... About 3-10% of pure germ cell tumors are embryonal carcinomas, and embryonal carcinomas are present in more than 80% of mixed ... Intratubular embryonal carcinoma. Dense, eosinophilic, necrotic debris in association with embryonal carcinoma cells is filling ...
Cancer J. 2014 Nov-Dec;20(6):397-402 Authors: McGovern SL, Grosshans D, Mahajan A Abstract Embryonal brain tumors are a ... Embryonal brain tumors. Cancer J. 2014 Nov-Dec;20(6):397-402 Authors: McGovern SL, Grosshans D, Mahajan A Abstract Embryonal ... Medulloblastoma is an embryonal tumor of the cerebellum and the most common malignant brain tumor in children, that occurs only ... Medulloblastoma is an embryonal tumor of the cerebellum and the most common malignant brain tumor in children, that occurs only ...
embryonal leukemia synonyms, embryonal leukemia pronunciation, embryonal leukemia translation, English dictionary definition of ... embryonal leukemia. n. Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained ... Embryonal leukemia - definition of embryonal leukemia by The Free Dictionary https://www.thefreedictionary.com/embryonal+ ... redirected from embryonal leukemia). Also found in: Thesaurus, Medical, Encyclopedia. leu·ke·mi·a. (lo͞o-kē′mē-ə). n.. Any of ...
embryonal medulloepithelioma synonyms, embryonal medulloepithelioma pronunciation, embryonal medulloepithelioma translation, ... English dictionary definition of embryonal medulloepithelioma. dictyoma. Translations. English: dic·ty·o·ma n. dictioma, tumor ... redirected from embryonal medulloepithelioma). Also found in: Medical. Translations. dic·ty·o·ma n. dictioma, tumor del ... In a similar way, the term embryonal medulloepithelioma is redundant.. Intraocular medulloepithelioma ...
Undifferentiated embryonal sarcoma of the liver (UESL) is a rare kind of liver cancer that happens mostly in children. ... What Is Undifferentiated Embryonal Sarcoma of the Liver (UESL)?. Undifferentiated embryonal sarcoma of the liver (UESL) is a ... Who Gets Undifferentiated Embryonal Sarcoma of the Liver (UESL)?. Most children who get undifferentiated embryonal sarcoma of ... Who Treats Undifferentiated Embryonal Sarcoma of the Liver (UESL)?. Undifferentiated embryonal sarcoma of the liver is treated ...
Search of: Embryonal sarcoma - Modify Search. Fill in any or all of the fields below. Click on the label to the left of each ...
An embryonal carcinoma is a malignant growth that develops in germ cells. Common types of embryonal carcinomas include ... An embryonal carcinoma is a malignant growth which develops in germ cells. These types of cancers can be seen in men, women, ... Treatment for an embryonal carcinoma can be supervised by an oncologist, who will work with other members of a medical team ... In men, embryonal carcinomas such as seminomas are often responsible for testicular cancer. If the cancer is allowed to grow, ...
Genetic manipulation of embryonal stem cells allows a wide range of precise genetic modifications. The chimaeric animals ... This volume provides an up-to-date review of this rapidly developing area of research, covering embryonal stem cells, ... cancer and psychiatric conditions.Embryonal Stem Cells: Introducing Planned Changes into the Animal Germline is the first ... Embryonal Stem Cells: Introducing Planned Changes Into the Animal Germline. Volume 1 of Modern genetics, ISSN 1056-4497. Volume ...
Fifteen of the 54 germ cell tumors containing embryonal carcinoma were also examined with antibodies to CD30. These embryonal ... The embryonal carcinoma of the testis is a germ cell neoplasm. Clinically, these tumors present much like other testicular ... OCT4 Staining in Testicular Tumors: A Sensitive and Specific Marker for Seminoma and Embryonal Carcinoma.. Jones TD, Ulbright ... It has been detected in primary testicular germ cell tumors with pluripotent potential, seminoma, and embryonal carcinoma. We ...
There are four types of nonmedulloblastoma embryonal tumors:. *Embryonal tumors with multilayered rosettes. Embryonal tumors ... Pineoblastomas are not a type of CNS embryonal tumor but treatment for them is a lot like treatment for CNS embryonal tumors. ... Central nervous system (CNS) embryonal tumors form in embryonic cells that remain in the brain after birth. CNS embryonal ... Nonmedulloblastoma embryonal tumors. Nonmedulloblastoma embryonal tumors are fast-growing tumors that usually form in brain ...
In addition, c-Ha-ras can stimulate the inactive Py enhancer in embryonal carcinoma F9 cells. c-Ha-ras activation in embryonal ... Disease relevance of Carcinoma, Embryonal. *Mouse teratocarcinoma stem cells (embryonal carcinoma, or EC cells) bind very small ... Biological context of Carcinoma, Embryonal. *Murine embryonal carcinoma cells (ECCs) do not express antigens of the major ... High impact information on Carcinoma, Embryonal. *All of these properties are induced in undifferentiated embryonal carcinoma ...
Embryonal tumors with multilayered rosettes (ETMR): Representing 11% of the 323 cases, this subtype combines embryonal rosette- ... Nonmedulloblastoma embryonal tumors. For nonmedulloblastoma embryonal tumors, presentation is also relatively rapid and depends ... Treatment of Recurrent Childhood CNS Embryonal Tumors. Recurrence of all forms of central nervous system (CNS) embryonal tumors ... Staging of Nonmedulloblastoma Embryonal Tumors. Patients with nonmedulloblastoma, nonmedulloepithelioma embryonal tumors are ...
Embryonal Fyn-associated substrateAdd BLAST. 560. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... sp,Q64355,EFS_MOUSE Embryonal Fyn-associated substrate OS=Mus musculus GN=Efs PE=1 SV=2 ...
Perianal and Perineal Spindle Cell Variant of Embryonal Rhabdomyosarcoma in an Infant.. Singh AP1, Mangal K2, Tanger R1, Gupta ... We present a case of a perianal and perianal spindle cell variant of embryonal rhabdomyosarcoma (RMS). A 3-month-old male child ... The histological examination and IHC stains were consistent with a spindle cell variant of embryonal RMS. ... Biopsy was performed; it showed embryonal RMS. Immunohistochemical (IHC) stains were performed using vimentin, myogenin, spinal ...
The mouse embryonal carcinoma lines PCC4-F and F9 have played important roles in the isolation and characterization of the two ... Previous Document: P19 embryonal carcinoma cells.. Next Document: Midkine (MK), the product of a retinoic acid responsive gene ... The mouse embryonal carcinoma lines PCC4-F and F9 have played important roles in the isolation and characterization of the two ...
embryonal childhood rhabdomyosarcoma. embryonal-botryoid childhood rhabdomyosarcoma. previously untreated childhood ... Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma. The safety and scientific ... Determine the progression-free survival rate in patients with low-risk embryonal rhabdomyosarcoma treated with intensive ... Genetic and Rare Diseases Information Center resources: Soft Tissue Sarcoma Rhabdomyosarcoma Embryonal ...
Using NTera2/clone D1 (NT2/D1) human embryonal carcinoma cells as a model, we report that the RA induced terminal ... Overexpression of the retinoic acid receptor gamma directly induces terminal differentiation of human embryonal carcinoma cells ...
Vincristine Dactinomycin and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma ... Diagnosis of embryonal rhabdomyosarcoma Primary operation for pathological diagnosis within the past 42 days The following ... Vincristine Dactinomycin and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma Are you eligible to ...
... and infantile embryonal carcinoma. They are a type of germ cell tumor that can be found in infants and adults. ... Yolk sac tumors (YST) are also known as endodermal sinus tumors (EST) and infantile embryonal carcinoma. ...
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject areas.
Undifferentiated embryonal sarcoma of liver: a multi-institutional experience with 9 cases. Int J Clin Exp Pathol. 2014; 7(12 ... Undifferentiated liver embryonal sarcoma in adults: A report of four cases and literature review. World J Gastroenterol. 2010; ... Undifferentiated embryonal sarcoma of the liver is a rare and highly aggressive primitive mesenchymal neoplasm that should be ... Undifferentiated embryonal sarcoma (UES) of the liver is an uncommon primitive mesenchymal tumor occurring mainly in the ...
This graph shows the total number of publications written about "Neoplasms, Germ Cell and Embryonal" by people in Harvard ... "Neoplasms, Germ Cell and Embryonal" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ... Below are the most recent publications written about "Neoplasms, Germ Cell and Embryonal" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Neoplasms, Germ Cell and Embryonal". ...
Diagnosis of embryonal rhabdomyosarcoma. - Primary operation for pathological diagnosis within the past 42 days. - The ... Determine the progression-free survival rate in patients with low-risk embryonal. rhabdomyosarcoma treated with intensive ...
Third report of t(19q)(13.4) in mesenchymal hamartoma of the liver with comments on link to embryonal sarcoma BOVE KE ... Undifferentiated embryonal sarcoma of the liver : results of clinical management in one center WEBER EM ... Non-random p53 mutations in pediatric undifferentiated (embryonal) sarcoma of the liver * * SANGKHATHAT Surasak ... Undifferentiated (embryonal) sarcoma arising in conjunction with mesenchymal hamartoma of the liver CHADAREVIAN J ...
Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy with a poor outcome. In this article, we describe a case of ERMS in the ... Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy with a poor outcome. In this article, we describe a case of ERMS in the ...
In the course of retinoic acid-induced differentiation of embryonal carcinoma cells the epitope disappeared before the onset of ... Unusual stage-specific embryonic antigen (TEC-4) defined by a monoclonal antibody to embryonal carcinoma cells defective in the ... One monoclonal antibody prepared by this strategy was found to react specifically with mouse embryonal carcinoma and embryo- ... Unusual stage-specific embryonic antigen (TEC-4) defined by a monoclonal antibody to embryonal carcinoma cells defective in the ...
  • Embryonal rhabdomyosarcoma (ERMS) is a rare histological form of cancer of connective tissue wherein the mesenchymally-derived malignant cells resemble the primitive developing skeletal muscle of the embryo. (wikipedia.org)
  • Perianal and Perineal Spindle Cell Variant of Embryonal Rhabdomyosarcoma in an Infant. (nih.gov)
  • We present a case of a perianal and perianal spindle cell variant of embryonal rhabdomyosarcoma (RMS). (nih.gov)
  • PURPOSE: This phase II trial is studying how well giving vincristine, dactinomycin, and cyclophosphamide together works in treating patients with embryonal rhabdomyosarcoma. (clinicaltrials.gov)
  • Determine the progression-free survival rate in patients with low-risk embryonal rhabdomyosarcoma treated with intensive chemotherapy comprising vincristine, dactinomycin, and cyclophosphamide followed by vincristine and dactinomycin. (clinicaltrials.gov)
  • Embryonal rhabdomyosarcoma of the paranasal sinuses: a case report and review of literature. (biomedsearch.com)
  • Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy with a poor outcome. (biomedsearch.com)
  • Embryonal rhabdomyosarcoma (ERMS) is a soft tissue cancer with features of skeletal muscle, and the most common soft tissue connective cancer of childhood. (alexslemonade.org)
  • TP53 Mutation, NRAS Mutation, NRAS Exon 3 Mutation, NRAS Exon 3 Missense, and NRAS Codon 61 Missense are the most common alterations in embryonal rhabdomyosarcoma [ 2 ]. (mycancergenome.org)
  • There are 3 clinical trials for embryonal rhabdomyosarcoma, of which 3 are open and 0 are completed or closed. (mycancergenome.org)
  • Of the trials that contain embryonal rhabdomyosarcoma as an inclusion criterion, 3 are phase 1/phase 2 (3 open). (mycancergenome.org)
  • ARAF, BRAF, and CRKL are the most frequent gene inclusion criteria for embryonal rhabdomyosarcoma clinical trials [ 3 ]. (mycancergenome.org)
  • Cobimetinib, dasatinib, and entinostat are the most common interventions in embryonal rhabdomyosarcoma clinical trials. (mycancergenome.org)
  • ARAF is an inclusion eligibility criterion in 1 clinical trial for embryonal rhabdomyosarcoma, of which 1 is open and 0 are closed. (mycancergenome.org)
  • Of the trial that contains ARAF status and embryonal rhabdomyosarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [ 3 ]. (mycancergenome.org)
  • HRAS is altered in 12.07% of embryonal rhabdomyosarcoma patients [ 2 ]. (mycancergenome.org)
  • MYCN is an inclusion eligibility criterion in 1 clinical trial for embryonal rhabdomyosarcoma, of which 1 is open and 0 are closed. (mycancergenome.org)
  • Of the trial that contains MYCN status and embryonal rhabdomyosarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [ 3 ]. (mycancergenome.org)
  • Following organizations serve the condition "Embryonal rhabdomyosarcoma" for support, advocacy or research. (diseaseinfosearch.org)
  • Finding the right clinical trial for Embryonal rhabdomyosarcoma can be challenging. (diseaseinfosearch.org)
  • The terms "Embryonal rhabdomyosarcoma" returned 94 free, full-text research articles on human participants. (diseaseinfosearch.org)
  • Embryonal rhabdomyosarcoma of the scalp: about a case]. (diseaseinfosearch.org)
  • Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells. (diseaseinfosearch.org)
  • This report describes the effects of GLPG1790, a new potent pan-EPH inhibitor, in human embryonal rhabdomyosarcoma (ERMS) cell lines. (diseaseinfosearch.org)
  • The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma. (diseaseinfosearch.org)
  • However, mechanisms regulating TPC self-renewal are largely unknown, especially in embryonal rhabdomyosarcoma (ERMS)-a common pediatric cancer of muscle. (diseaseinfosearch.org)
  • The terms "Embryonal rhabdomyosarcoma" returned 4 free, full-text review articles on human participants. (diseaseinfosearch.org)
  • Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient - case report and review of clinicopathological features. (diseaseinfosearch.org)
  • A recurrent embryonal rhabdomyosarcoma (ERMS) of the broad ligament, first diagnosed at age 23 years, harboured biallelic pathogenic somatic DICER1 variants (1 truncating and 1 RNase IIIb missense). (eur.nl)
  • Embryonal rhabdomyosarcoma (RMS) is a rare type of sarcoma, primarily seen in the pediatric and adolescent population. (cureus.com)
  • Immunohistochemical stains were positive for vimentin, CD99, myogenin, and MyoD1 consistent with a diagnosis of embryonal rhabdomyosarcoma, botryoid subtype. (cureus.com)
  • The cervix appeared dilated, with a protruding friable mass that was biopsied with pathology consistent with embryonal rhabdomyosarcoma. (cureus.com)
  • Orbit Embryonal Rhabdomyosarcoma, also known as embryonal rhabdomyosarcoma of the orbit , is related to orbit rhabdomyosarcoma and embryonal rhabdomyosarcoma . (malacards.org)
  • An important gene associated with Orbit Embryonal Rhabdomyosarcoma is MB (Myoglobin). (malacards.org)
  • Embryonal rhabdomyosarcoma of the orbit in a liver transplant recipient. (malacards.org)
  • Letter to the editor: neurofibromatosis type 1 (NF 1) associated with embryonal rhabdomyosarcoma of the orbit. (malacards.org)
  • Microsatellite instability in three cases of embryonal rhabdomyosarcoma of the orbit. (malacards.org)
  • Embryonal rhabdomyosarcoma of the orbit in a 38-year-old woman. (malacards.org)
  • Cell necrosis and endocytosis (apoptosis) in an embryonal rhabdomyosarcoma of the orbit. (malacards.org)
  • Electron microscopic and electron histochemical studies on embryonal rhabdomyosarcoma of the orbit. (malacards.org)
  • To date, only three cases of spindle cell subtype of embryonal rhabdomyosarcoma of the prostate in an adult have been published. (lemar.tv)
  • For example, the overall 5-year survival for children with RMS is about 70%, The prognosis of embryonal rhabdomyosarcoma is very favorable when no metastatic disease is present. (lemar.tv)
  • presentation and response of embryonal rhabdomyo- sarcoma to therapy is different from that of childhood embryonal rhabdomyosarcoma prompted this study. (lemar.tv)
  • There are two types of rhabdomyosarcoma: embryonal and alveolar. (lemar.tv)
  • Case presentation: We report an additional case of prostatic spindle cell embryonal rhabdomyosarcoma subtype in an adult. (lemar.tv)
  • For example, children with embryonal rhabdomyosarcoma (ERMS) and limited spread (to only 1 or 2 distant sites) have a higher 5-year survival rate. (lemar.tv)
  • Another common area for embryonal rhabdomyosarcoma to develop is the genitourinary system. (macmillan.org.uk)
  • According to the WHO classification of soft tissue tumors, there are four distinct subentities of rhabdomyosarcoma and they include embryonal , alveolar, pleomorphic, and spindle cell/sclerosing subtype. (freethesaurus.com)
  • Embryonal rhabdomyosarcoma (eRMS) is one of the most common soft tissue sarcomas in children and adolescents. (elsevier.com)
  • Patients with embryonal rhabdomyosarcoma are predominantly male (male to female ratio, 1.5). (oncolink.org)
  • High birth weight and large size for gestational age are associated with an increased incidence of embryonal rhabdomyosarcoma. (oncolink.org)
  • A 14-month-old Maine coon was diagnosed with an embryonal rhabdomyosarcoma in the rectus abdominus muscle, which was treated with complete surgical excision. (elsevier.com)
  • The histological diagnosis was embryonal rhabdomyosarcoma (myotubular subtype). (elsevier.com)
  • Undifferentiated embryonal sarcoma of the liver (UESL) is a rare kind of liver cancer that happens mostly in children. (kidshealth.org)
  • What Are the Signs & Symptoms of Undifferentiated Embryonal Sarcoma of the Liver (UESL)? (kidshealth.org)
  • Who Gets Undifferentiated Embryonal Sarcoma of the Liver (UESL)? (kidshealth.org)
  • Most children who get undifferentiated embryonal sarcoma of the liver are 6 to 10 years old. (kidshealth.org)
  • How Is Undifferentiated Embryonal Sarcoma of the Liver (UESL) Diagnosed? (kidshealth.org)
  • How Is Undifferentiated Embryonal Sarcoma of the Liver (UESL) Treated? (kidshealth.org)
  • Undifferentated (embryonal) sarcoma of the liver. (nii.ac.jp)
  • Embryonal Sarcoma, also known as undifferentiated sarcoma , is related to undifferentiated embryonal sarcoma of the liver and fibrous histiocytoma , and has symptoms including fever An important gene associated with Embryonal Sarcoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Endometrial cancer and PI3K-Akt signaling pathway . (malacards.org)
  • Undifferentiated embryonal sarcoma of the liver (UESL) is a rare neoplasm, and the third-most common paediatric hepatic malignaney. (scielo.org.za)
  • Undifferentiated embryonal sarcoma of the liver (UESL) is a rare hepatic neoplasm that occurs mainly in children. (scielo.org.za)
  • At just 14 the teenager was believed to be only the second person in the country to be diagnosed with undifferentiated embryonal sarcoma of the liver. (thefreedictionary.com)
  • Undifferentiated embryonal sarcoma of the liver successfully treated with chemotherapy and liver resection. (thefreedictionary.com)
  • Undifferentiated embryonal sarcoma of the liver (UESL) is a rare and aggressive malignancy. (prolekare.cz)
  • Characteristics and outcomes in children with undifferentiated embryonal sarcoma of the liver: A report from the National Cancer Database. (prolekare.cz)
  • Treatment of undifferentiated embryonal sarcoma of the liver in children-single center experience. (prolekare.cz)
  • Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. (prolekare.cz)
  • Undifferentiated embryonal sarcoma of the liver (UESL) is an extremely rare neoplasm in adults with less than 60 cases described so far in the literature [1-7]. (freethesaurus.com)
  • Mutations in the RAS/NF1 pathway are significantly associated with intermediate- and high-risk embryonal rhabdomyosarcomas (ERMS). (nih.gov)
  • Overexpression of the retinoic acid receptor gamma directly induces terminal differentiation of human embryonal carcinoma cells. (nih.gov)
  • Using NTera2/clone D1 (NT2/D1) human embryonal carcinoma cells as a model, we report that the RA induced terminal differentiation of these cells into a neuronal phenotype is characterized by an increase in expression of RAR alpha, RAR beta, RAR gamma, and a slight induction of RXR alpha. (nih.gov)
  • Expression Profiling of Lineage Differentiation in Pluripotential Human Embryonal Carcinoma Cells -- Houldsworth et al. (aacrjournals.org)
  • This PDQ cancer information summary has current information about the treatment of childhood central nervous system embryonal tumors. (oncolink.org)
  • Embryonal carcinoma is a germ cell tumor characterized by primitive epithelial cells with marked pleomorphism and various histologic patterns. (medscape.com)
  • As with other germ cell tumors, with the exception of spermatocytic seminoma , embryonal carcinomas are believed to originate from intratubular malignant germ cells. (medscape.com)
  • Association of embryonal carcinomas with syncytiotrophoblastic giant cells may cause increases in serum human chorionic gonadotropin (hCG) levels. (medscape.com)
  • Embryonal' means that the cancer probably grew from cells early in a fetus' development that didn't change (differentiate) into liver cells properly. (kidshealth.org)
  • An embryonal carcinoma is a malignant growth which develops in germ cells . (wisegeek.com)
  • Embryonal Stem Cells: Introducing Planned Changes into the Animal Germline is the first volume in the Modern Genetics book series. (google.com)
  • Genetic manipulation of embryonal stem cells allows a wide range of precise genetic modifications. (google.com)
  • This volume provides an up-to-date review of this rapidly developing area of research, covering embryonal stem cells, homologous recombination and gene targeting, germline transmission of planned genomic modifications and research strategies using genetically modified animals. (google.com)
  • In all cases of mixed germ cell tumor with components of embryonal carcinoma (54) and seminoma (51), there was greater than 90% nuclear staining of the embryonal carcinoma and seminoma tumor cells with little to no background staining. (thedoctorsdoctor.com)
  • These embryonal carcinoma components were all positive for CD30 with staining of greater than 90% of the tumor cells but with variable staining intensity. (thedoctorsdoctor.com)
  • Central nervous system (CNS) embryonal tumors may begin in embryonic (fetal) cells that remain in the brain after birth. (oncolink.org)
  • Central nervous system (CNS) embryonal tumors form in embryonic cells that remain in the brain after birth. (oncolink.org)
  • Nonmedulloblastoma embryonal tumors are fast-growing tumors that usually form in brain cells in the cerebrum. (oncolink.org)
  • P19 embryonal carcinoma cells. (biomedsearch.com)
  • Most developmentally regulated epitopes identified on embryonal carcinoma cells and murine preimplantation embryos are associated with a glycoprotein-bound large glycan called embryoglycan. (pnas.org)
  • To prepare monoclonal antibodies recognizing other, less immunogenic stage-specific embryonic epitopes, we used embryoglycan-negative embryonal carcinoma cells P19XT.1.1 as immunogen. (pnas.org)
  • In the course of retinoic acid-induced differentiation of embryonal carcinoma cells the epitope disappeared before the onset of morphological differentiation. (pnas.org)
  • Human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and they are key components of germ cell tumors (GCTs). (aacrjournals.org)
  • 1995 ) A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. (biologists.org)
  • Proviral sequences that restrict retroviral expression in mouse embryonal carcinoma cells. (asm.org)
  • Embryonal carcinoma (EC) cells are nonpermissive for retrovirus replication. (asm.org)
  • Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells. (asm.org)
  • Mouse embryonal carcinoma (EC) cells are the only mammalian cells known to exhibit HSE-binding activity, as determined by gel shift assays, even when maintained at normal physiological temperatures. (asm.org)
  • Embryonal tumours with multilayered rosettes (ETMS) are characterized by undifferentiated neuroepithelial cells resembling those of classic CNS PNET , abundant well-differentiated neuropil, and ependymoblastic rosettes scattered throughout paucicellular regions of neoplastic neuropil. (radiopaedia.org)
  • Defective expression of adenovirus genes during early infection of undifferentiated OTF963 embryonal carcinoma cells. (asm.org)
  • These results suggest limits to the generality and explanatory power of the hypothesis that F9 embryonal carcinoma cells contain an E1a-like factor. (asm.org)
  • Human embryonal carcinoma (EC) cells comprise the pluripotent stem cells of malignant non-seminomatous germ cell tumors (GCTs) and represent the malignant counterpart of embryonic stem cells (ESCs). (eur.nl)
  • Substantial multiplication in vitro of cloned cells from a human embryonal carcinoma cell line, Tera 2, has been obtained in a basal medium (DMEM/Ham's F12,50:50, v/v) supplemented with 10 micrograms low density lipoprotein/ml, 100 micrograms high density lipoprotein/ml, 100 ng multiplication stimulating activity/ml, 100 ng insulin/ml and 1 microgram transferrin/ml. (biologists.org)
  • In this study, we describe a model system in which multipotential mouse P19 embryonal carcinoma cells (P19s) can be induced to express multiple characteristics of differentiated smooth muscle. (ahajournals.org)
  • We have introduced human mini-chromosomes of 4 Mb and ∼15 Mb in size into mouse embryonal stem cells. (oup.com)
  • Although these human mini-chromosomes are stable in hamster and chicken cells, they re-arrange or segregate aberrantly in the embryonal stem cells and are rapidly lost in the absence of selection. (oup.com)
  • Early Cycling-independent Changes to p27, Cyclin D2, and Cyclin D3 in Differentiating Mouse Embryonal Carcinoma Cells -- Preclíková et al. (aacrjournals.org)
  • Polyoma virus can develop lytically in differentiated mouse cells, but is unable to express either early or late functions in undifferentiated early embryonic cells or in embryonal carcinoma (EC) cells of the mouse. (pasteur.fr)
  • Differentiated clonal cell lines were isolated from pluripotent P19 embryonal carcinoma (EC) cells treated as aggregates with retinoic acid. (uu.nl)
  • Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells. (rupress.org)
  • The lamin complement of nuclear matrix isolated from F9 embryonal carcinoma cells was studied during retinoic acid-induced differentiation in culture. (rupress.org)
  • Tsymbaluk V.I., Vasilyeva I.G., Olexenko N.P., Chopic N.G., Tsybko O.I., Galanta E.S. Dophaminergic cell differentiation from the human embryonal nerve cells in vitro, Tsitol Genet. (cytgen.com)
  • Linzer, DIH , Maltzman, W & Levine, AJ 1979, ' Characterization of a murine cellular SV40 T antigen in SV40-transformed cells and uninfected embryonal carcinoma cells ', Symposia on Quantitative Biology , vol. 44, no. 1, pp. 215-224. (northwestern.edu)
  • Persistance of CD30 expression in embryonal carcinoma (EC) cells: a retrospective study in multi-relapsed or chemotherapy (CT) refractory germ-cell. (esmo.org)
  • Embryonal tumors are a rare group of rapidly growing highly malignant tumors that afflict infants and your children and that are thought to have arisen from some slight fault in embryonic development leaving just one, or at the most a few, developing cells independent of the usual regulatory restraints. (curepages.com)
  • Cancer J. 2014 Nov-Dec;20(6):397-402 Authors: McGovern SL, Grosshans D, Mahajan A Abstract Embryonal brain tumors are a heterogeneous group of neoplasms that primarily occur in infants and young children. (medworm.com)
  • We examined histologic sections from 91 primary testicular neoplasms, including 64 cases of mixed germ cell tumors containing embryonal carcinoma (54), seminoma (51), yolk sac tumor (38), mature teratoma (31), immature teratoma (20), and choriocarcinoma (15). (thedoctorsdoctor.com)
  • Neoplasms, Germ Cell and Embryonal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Neoplasms, Germ Cell and Embryonal" by people in Harvard Catalyst Profiles by year, and whether "Neoplasms, Germ Cell and Embryonal" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Neoplasms, Germ Cell and Embryonal" by people in Profiles. (harvard.edu)
  • Embryonal tumors include a heterogeneous group of highly malignant neoplasms that primarily affect infants and children and are characterized by a high rate of mortality and treatment-related morbidity, hence improved therapies are clearly needed. (uzh.ch)
  • These ocular neoplasms have been compared with intracranial medulloepitheliomas or other histologic variants of CNS embryonal tumor with multilayered rosettes (CNS ETMR) due to their morphological mimicry. (elsevier.com)
  • The clinical features associated with metastasising embryonal carcinoma may include low back pain, dyspnoea, cough, haemoptysis, haematemesis and neurologic abnormalities. (wikipedia.org)
  • The embryonal carcinoma of the testis is a germ cell neoplasm. (thedoctorsdoctor.com)
  • They performed a multivariable analysis that only included variables found to be significant at the 5% level in the univariate analysis, which were elevation of hCG, presence of vascular invasion, invasion of rete testis, tunica albuginea, or epididymis, and presence of embryonal carcinoma, yolk sac tumour, choriocarcinoma, or teratoma. (freethesaurus.com)
  • Genomic analysis shows that embryonal tumors have more structural and copy number variations than alveolar tumors. (nih.gov)
  • Vascular invasion and determination of percentage of embryonal carcinoma should be assessed for all clinical stage I nonseminomatous germ cell tumor patients and the model presented herein can be used clinically to predict the likelihood of occult disease and dictate therapy. (aacrjournals.org)
  • About 3-10% of pure germ cell tumors are embryonal carcinomas, and embryonal carcinomas are present in more than 80% of mixed germ cell tumors. (medscape.com)
  • [ 5 ] In the vast majority of cases, IGCNU occurs adjacent to invasive germ cell tumors, including embryonal carcinomas. (medscape.com)
  • Embryonal carcinomas are located in the testicular parenchyma. (medscape.com)
  • Embryonal carcinomas are aggressive germ cell tumors. (medscape.com)
  • Although serum alpha fetoprotein (AFP) has been reported in association with embryonal carcinomas, most of those cases were probably misclassified as such and in truth represented mixed cases of embryonal carcinomas and yolk sac tumors . (medscape.com)
  • Embryonal carcinomas usually present as ill-defined masses. (medscape.com)
  • In men, embryonal carcinomas such as seminomas are often responsible for testicular cancer. (wisegeek.com)
  • We conclude that immunostaining with antibodies to OCT4 is a useful diagnostic tool in the identification of primary testicular embryonal carcinomas and "usual," but not spermatocytic, seminomas. (thedoctorsdoctor.com)
  • The quassinoid analogue NBT-272 has been reported to inhibit MYC, thus warranting a further effort 7to better understand its preclinical properties in models of embryonal tumors (ET), a family of childhood malignancies sharing relevant biological and genetic features such as deregulated expression of MYC oncogenes. (aacrjournals.org)
  • A molecularly distinct entity, embryonal tumor with multilayered rosettes (ETMR), C19MC -altered, has been added, encompassing embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma. (cancer.gov)
  • Previously embryonal tumours with multilayered rosettes (ETMR) were known as embryonal tumour with abundant neuropil and true rosettes (ETANTR) . (radiopaedia.org)
  • Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update. (radiopaedia.org)
  • Embryonal tumors with abundant neuropil and true rosettes: a distinctive CNS primitive neuroectodermal tumor. (radiopaedia.org)
  • Embryonal tumor with abundant neuropil and true rosettes: an autopsy case-based update and review of the literature. (radiopaedia.org)
  • OCT4 Staining in Testicular Tumors: A Sensitive and Specific Marker for Seminoma and Embryonal Carcinoma. (thedoctorsdoctor.com)
  • It has been detected in primary testicular germ cell tumors with pluripotent potential, seminoma, and embryonal carcinoma. (thedoctorsdoctor.com)
  • Primary tumor pathological material was analyzed for vascular invasion, lymphatic invasion, tunical invasion, and quantitative determination of percentage of the primary tumor composed of embryonal carcinoma, yolk sac carcinoma, teratoma, and seminoma. (aacrjournals.org)
  • Univariate logistic regression analyses revealed that vascular invasion ( P = 0.0001), percentage of embryonal carcinoma ( P = 0.0001), lymphatic invasion ( P = 0.0001), and tunical invasion ( P = 0.0013) were higher in pathological stage II and that percentage of teratoma ( P = 0.0001) and of yolk sac carcinoma ( P = 0.0174) were higher in stage I. Percentage of seminoma was not significant. (aacrjournals.org)
  • TGCTs are classified into two major histologic subgroups, seminoma and nonseminoma: nonseminomatous TGCTs show embryonal and extraembryonal differentiation patterns, which include primitive zygotic (embryonal carcinoma, EC), embryonal-like somatic differentiated (teratoma), and extraembryonally differentiated (choriocarcinoma, yolk sac tumor) phenotypes ( 2 ). (aacrjournals.org)
  • OCT4 is a sensitive and specific marker for diagnosing seminoma, dysgerminoma, germinoma, and embryonal carcinoma [2]. (freethesaurus.com)
  • Embryonal brain tumors. (medworm.com)
  • Primary brain tumors, including embryonal tumors, are a diverse group of diseases that together constitute the most common solid tumor of childhood. (cancer.gov)
  • It is noteworthy that nowadays PNET are defined as embryonal tumors according to the 2016 version of the OMS brain tumors classification [2]. (freethesaurus.com)
  • We discuss the botryoid subtype of embryonal RMS in an older female with a bulky tumor removed in its entirety and treated with adjuvant chemotherapy. (cureus.com)
  • If the cancer is an embryonal carcinoma, treatment options can include surgery, chemotherapy, and radiation. (wisegeek.com)
  • In this review we examine approaches to DNA targeted cancer therapy, summarize the recent developments of G-quadruplex ligands as anticancer drugs and speculate on the future direction of such structures as a potential novel therapeutic strategy for embryonal tumors of the nervous system. (uzh.ch)
  • Her cancer is called undifferentiated hepatic embryonal sarcoma , a difficult-to-treat liver cancer that is complicated in Ashley's case by the fact that the tumor has impinged upon the blood vessels supplying her liver. (thefreedictionary.com)
  • All such embryonal tumors growths are characterized by their precocious age incidence and by their tendency towards rapid growth and extreme invasiness, although as everywhere in cancer variants can occur, with some examples exhibiting slower growth and with clinical recognition delayed until late childhood. (curepages.com)
  • Following Piccolo's death, the Brian Piccolo Cancer Research Fund was established and proceeds were sent to the Sloan-Kettering Cancer Center in New York for research on embryonal cell carcinoma. (freethesaurus.com)
  • Undifferentiated embryonal sarcoma (UES) of the liver is an uncommon primitive mesenchymal tumor occurring mainly in the pediatric population with a predominant age range of 6-10 yrs. (appliedradiology.com)
  • OCT4 immunostaining has comparable sensitivity but greater consistency compared with CD30 in the diagnosis of embryonal carcinoma. (thedoctorsdoctor.com)
  • The pathologic diagnosis of embryonal tumors is based primarily on histological and immunohistological microscopic features. (cancer.gov)
  • Retinoic acid induces neuronal differentiation of embryonal. (pubpeer.com)
  • If caught early, the prognosis for someone with an embryonal carcinoma can be very good, as these cancers generally respond well to chemotherapy and radiation. (wisegeek.com)
  • The availability of a large number of knockout mice is a potential rich source of immortalized mutant mouse embryonal fibroblasts (MEF) with defined gene deficiencies. (aacrjournals.org)
  • Many other genes might also be involved in the pathogenesis of UM such as the Ras and EF-hand domain containing (RASEF) gene, RAB31, hTERT, embryonal fyn-associated substrate, and deleted in split-hand/split-foot 1. (freethesaurus.com)
  • Males with pure embryonal carcinoma tend to have a normal amount of the protein alpha-fetoprotein in the fluid component of their blood. (wikipedia.org)
  • We present a rare case of MSCCS as the initial presentation of a pure testicular embryonal carcinoma. (freethesaurus.com)
  • Testicular embryonal carcinoma - Chemotherapy. (bookinghealth.com)
  • The histological examination and IHC stains were consistent with a spindle cell variant of embryonal RMS. (nih.gov)
  • Embryonal carcinoma and teratocarcinoma are common between the ages of 25 and 35, and choriocarcinoma is common in the ages of 20-30. (freethesaurus.com)
  • The murine embryonal teratocarcinoma cell line, P19, was genetically manipulated in order to provide preliminary information on compounds that induce differentiation. (atla.org.uk)
  • These findings combined with biopsy confirmed undifferentiated embryonal sarcoma (UES). (appliedradiology.com)
  • Embryonal rhabdomyosarcomas are uncommon tumors in all domestic species, especially cats. (elsevier.com)
  • Yolk sac tumors (YST) are also known as endodermal sinus tumors (EST) and infantile embryonal carcinoma . (knowcancer.com)
  • Signs and symptoms of childhood CNS embryonal tumors or pineoblastomas depend on the child's age and where the tumor is. (oncolink.org)
  • Tests that examine the brain and spinal cord are used to detect (find) childhood CNS embryonal tumors or pineoblastomas. (oncolink.org)
  • Given that therapies for pineoblastomas are quite similar to those utilized for embryonal tumors, pineoblastomas are discussed in this summary. (cancer.gov)
  • Moreno, Lucas 2017-12-16 00:00:00 Non-medulloblastoma CNS embryonal tumors (former PNET/Pineoblastomas) are aggressive malignancies with poor outcome that have been historically treated with medulloblastoma protocols. (deepdyve.com)
  • Disclaimer: Embryonal carcinoma definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. (definithing.com)
  • Embryonal tumours with multilayered rosettes (ETMR) are rare small round blue cell tumour of the central nervous system and are one of the most aggressive brain tumours usually encountered in children. (radiopaedia.org)
  • This term has, however, been removed from the 2016 update to WHO classification of CNS tumours in favour of embryonal tumours with multilayered rosettes (ETMR) which incorporates not only ETANTR but also ependymoblastoma and CNS PNET which have also been removed from the classification) 6 . (radiopaedia.org)
  • As a result, both ETANTR and CNS PNET have been removed from the 2016 update of the WHO classification of CNS tumours and been replaced by the term embryonal tumour with multilayered rosettes (ETMR), C19MC-altered (or ETMR-NOS if C19MC amplification is absent) 6 . (radiopaedia.org)
  • Expert-reviewed information summary about the treatment of childhood medulloblastoma, nonmedulloblastoma embryonal tumors, and pineal tumors. (oncolink.org)
  • Management and outcome of children and adolescents with non-medulloblastoma CNS embryonal tumors. (deepdyve.com)