A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.
The preparation and analysis of samples on miniaturized devices.
Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.
A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992)
An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current.
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
The design or construction of objects greatly reduced in scale.
Silicone polymers which consist of silicon atoms substituted with methyl groups and linked by oxygen atoms. They comprise a series of biocompatible materials used as liquids, gels or solids; as film for artificial membranes, gels for implants, and liquids for drug vehicles; and as antifoaming agents.
Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.
Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
A nonlinear electrophoretic technique used to separate a variety of ionic compounds, ranging from small metal ions to large molecules like proteins. Unlike "linear" zone electrophoresis in which separating solute bands continually spread by diffusion or dispersion, isotachophoresis forms self-sharpening, adjacent zones of substantially pure solute whose concentrations often exceed several mgs/ml. In isotachophoresis a multianalyte sample is introduced between the leading electrolyte and the terminating electrolyte where the sample ions have lower electrophoretic mobilities than the leading ion but larger than the terminating ion. (From "Isotachophoresis" on the AES Web Site [Internet]. Madison, WI: The American Electrophoresis Society; c2000-2008 [cited 2009 Aug 20]. Available from http://www.aesociety.org/areas/isotachophoresis.php)
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
Procedures for recognizing individual animals and certain identifiable characteristics pertaining to them; includes computerized methods, ear tags, etc.
Electrophoresis in which agar or agarose gel is used as the diffusion medium.
The study of fluid channels and chambers of tiny dimensions of tens to hundreds of micrometers and volumes of nanoliters or picoliters. This is of interest in biological MICROCIRCULATION and used in MICROCHEMISTRY and INVESTIGATIVE TECHNIQUES.
Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.
Small computers using LSI (large-scale integration) microprocessor chips as the CPU (central processing unit) and semiconductor memories for compact, inexpensive storage of program instructions and data. They are smaller and less expensive than minicomputers and are usually built into a dedicated system where they are optimized for a particular application. "Microprocessor" may refer to just the CPU or the entire microcomputer.
The sum of the weight of all the atoms in a molecule.
Methods of creating machines and devices.
QUATERNARY AMMONIUM COMPOUNDS containing three methyl groups, having the general formula of (CH3)3N+R.
The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
Antibodies that are chemically bound to a substrate material which renders their location fixed.
Colorless, odorless crystals that are used extensively in research laboratories for the preparation of polyacrylamide gels for electrophoresis and in organic synthesis, and polymerization. Some of its polymers are used in sewage and wastewater treatment, permanent press fabrics, and as soil conditioning agents.
An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
Laboratory and other services provided to patients at the bedside. These include diagnostic and laboratory testing using automated information entry.
Electrophoresis in which discontinuities in both the voltage and pH gradients are introduced by using buffers of different composition and pH in the different parts of the gel column. The term 'disc' was originally used as an abbreviation for 'discontinuous' referring to the buffers employed, and does not have anything to do with the shape of the separated zones.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.
Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific. They are important molecular agents in the process of sperm maturation.
Measuring instruments for determining the temperature of matter. Most thermometers used in the field of medicine are designed for measuring body temperature or for use in the clinical laboratory. (From UMDNS, 1999)
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Measurement of the temperature of a material, or of the body or an organ by various temperature sensing devices which measure changes in properties of the material that vary with temperature, such as ELASTICITY; MAGNETIC FIELDS; or LUMINESCENCE.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Electrophoresis in which a starch gel (a mixture of amylose and amylopectin) is used as the diffusion medium.
The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.
Laboratory tests demonstrating the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease.
Electrophoresis applied to BLOOD PROTEINS.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.
Electrophoresis in which cellulose acetate is the diffusion medium.
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
A group of 1,2-benzenediols that contain the general formula R-C6H5O2.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Inorganic compounds that contain lithium as an integral part of the molecule.
Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.
Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
Electrophoresis in which various denaturant gradients are used to induce nucleic acids to melt at various stages resulting in separation of molecules based on small sequence differences including SNPs. The denaturants used include heat, formamide, and urea.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
Electrophoresis in which a pH gradient is established in a gel medium and proteins migrate until they reach the site (or focus) at which the pH is equal to their isoelectric point.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.
Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).

Optimization of an interface chip for coupling capillary electrophoresis with thermal lens microscopic detection. (1/135)

This paper presents a capillary-to-microchip connection, which can be used as an interface for coupling capillary electrophoresis (CE) with a thermal lens microscope (TLM). It is difficult to directly apply TLM to samples in a capillary with a curved surface, and such an interface chip at the end of a CE separation column is needed for reliable TLM measurements. The dependence of the TLM signal intensity on the TLM detection point in the interface chip and the dependence of the theoretical plate number of CE separation on the channel dimensions of the interface chip were investigated and optimized with a mixture of 4-dimethylaminoazobenze-4'-sulfonyl (DABSYL)-derivatized amino acids (glycine, alanine, methionine, and proline) as a model sample. By using an optimized interface chip, theoretical plate numbers of DABSYL-glycine, -methionine, -alanine, and -proline were obtained to be 104000, 95000, 104000, and 95000, respectively.  (+info)

Rapid microvolume PCR of DNA confirmed by microchip electrophoresis. (2/135)

PCR is an indispensable technique used in DNA analysis. However, with the traditional methods, the time spent on amplification and the subsequent analysis of PCR products is generally long. Therefore, it is essential to improve these two steps so that the whole procedure can be made faster. In the present work, with lambda-DNA as the control template, the amplification of 300-bp fragment could be completed within 37 s with capillary reaction chambers of LightCycler, and the following analysis of PCR products could be completed within 120 s with microchip electrophoresis as the detector. Since the high detection sensitivity of microchip electrophoresis, PCR products with template concentration as low as 5 fg/microL could be detected only after 435 s of amplification. In addition, based on additional optimized conditions simulated by CoventorWare, PCR microchips with distinct structure of the reaction chambers have been designed and successfully applied to the amplification of 300-bp fragment. By comparison, those chambers with ellipse and racket shapes were found to offer very high amplification efficiency. All of these results demonstrate the promise of integrating PCR and electrophoresis on microchip for developing easy-carrying instruments for the fast in situ detection of DNA.  (+info)

Rapid separation of microorganisms by quartz microchip capillary electrophoresis. (3/135)

We developed and optimized a system coupling microchip capillary electrophoresis (MCE) and laser-induced fluorescence (LIF) detection for the analysis of microorganisms. The MCE-LIF system successfully separated pure cultures of lactic acid bacteria and Saccharomyces cerevisiae within 200 s. The results indicate that the MCE system can be conveniently used for the rapid and highly sensitive detection of microorganisms. Thus, MCE can provide a cheap and simple method for the on-line detection of microbial contamination.  (+info)

Rapid enantioseparation of 1-aminoindan by microchip electrophoresis with linear-imaging UV detection. (4/135)

Chiral separations of 1-aminoindan (AI) by cyclodextrin electrokinetic chromatography (CDEKC) were investigated on microfluidic quartz chips. By using a microchip electrophoresis (MCE) instrument equipped with a linear-imaging UV detector, the separation process of the enantiomeric compounds was observed. When sulfated beta-cyclodextrin was employed as a chiral selector, the baseline separation of AI could be achieved within 1 min with a high repeatability. The relative standard deviation of the migration time was less than 6%. The fastest separation was achieved in 14 s, utilizing a separation length of only 6.1 mm. These results show that the MCE analysis employing a linear imaging UV detector has a significant potential for fast chiral analysis.  (+info)

Chiral separation of NBD-amino acids by ligand-exchange micro-channel electrophoresis. (5/135)

The chiral separation of amino acid derivatives by ligand-exchange electrophoresis in a microchannel chip was performed for the first time. A Cu(II) complex with L-prolinamide was used as a chiral selector. The migration behaviors of eleven NBD-DL-amino acids were investigated by ligand-exchange capillary electrophoresis (LE-CE). The enantiomer of five NBD-amino acids (Ser, Thr, Val, Phe and His) could be separated by LE-CE using a 20 mM ammonium acetate buffer (pH 9.0) containing 10 mM copper acetate, 20 mM L-prolinamide and 1 mM SDS. NBD-His was eluted in the order D-form and L-form, while the elution order of another enantiomers was L-form and D-form. Under this condition, the enantioseparation of these five NBD-amino acids by ligand-exchange microchip electrophoresis (LE-ME) was investigated using a glass microchip. The enantioseparation of NBD-Ser, -Thr and -His could be successfully accomplished by LE-ME. LE-ME was superior to LE-CE in terms of the short migration time and a good enantiomeric separation.  (+info)

Rapid identification of staphylococcal strains from positive-testing blood culture bottles by internal transcribed spacer PCR followed by microchip gel electrophoresis. (6/135)

PCR analysis of the 16S-23S rRNA gene internal transcribed spacer (ITS) followed by microchip gel electrophoresis (MGE) was evaluated for its usefulness in identification of staphylococci. Forty ITS PCR patterns were demonstrated among 228 isolated colonies of Staphylococcus aureus: 26 patterns for methicillin-susceptible S. aureus (MSSA; 91 strains), 11 patterns for methicillin-resistant S. aureus (MRSA; 99 strains), and 3 patterns for both MSSA and MRSA (38 strains). Thirty-seven control strains of coagulase-negative staphylococci (CNS) representing 16 species showed unique ITS PCR patterns (24 patterns) at the species and subspecies levels: two patterns for S. caprae, S. cohnii, S. haemolyticus, and S. saprophyticus; three patterns for S. lugdunensis; four patterns for S. capitis; and one pattern for each of the other CNS species. The combined PCR-MGE method was prospectively adapted to the positive blood culture bottles, and this method correctly identified MSSA and MRSA in 102 (89%) of 114 blood cultures positive for S. aureus on the basis of the ITS PCR patterns. Eight ITS PCR patterns were demonstrated from 166 blood culture bottles positive for CNS. The most frequent CNS species isolated from blood cultures were S. epidermidis (76%), S. capitis (11%), and S. hominis (8%). Overall, all 280 blood culture bottles shown to contain a single Staphylococcus species by routine phenotypic methods were correctly identified by the PCR-MGE method at the species level, whereas the organism failed to be identified in 8 culture bottles (3%) with mixed flora. The PCR-MGE method is useful not only for rapid identification ( approximately 1.5 h) of staphylococci in positive blood culture bottles, but also for strain delineation of S. aureus.  (+info)

B-cell clonality determination using an immunoglobulin kappa light chain polymerase chain reaction method. (7/135)

To augment the detection of clonality in B-cell malignancies, we designed a consensus primer kappa light chain gene (Igkappa) polymerase chain reaction (PCR) assay in combination with a consensus primer immunoglobulin heavy chain gene (IgH) PCR assay. Its efficacy was then evaluated in a series of 86 paraffin tissue samples comprising neoplastic and reactive lymphoproliferations. Analysis after PCR was accomplished by 10% native polyacrylamide gel electrophoresis after heteroduplex pretreatment of PCR products and by a post-PCR chip-based capillary electrophoresis analytic method. Overall, 49 of 68 (72%) of mature B-cell neoplasms yielded discrete Igkappa gel bands within the predicted size range with no clonotypic Igkappa products observed among reactive lymphoid or T-cell proliferations. The application of Igkappa PCR improved overall sensitivity from 81% with IgH PCR alone to 90% with combined Igkappa/IgH PCR, with this effect being most notable in germinal center-related lymphomas. Sequencing of positive Igkappa rearrangements revealed that most rearrangements involved members of the Vkappa1 (40%) and Vkappa2 (34%) gene families along with Jkappa1 (26%), Jkappa2 (23%), and Jkappa4 (51%) gene segments. Involvement of Vkappa pseudogenes was identified in 24% of cases with Vkappa-KDE rearrangements. Our results demonstrate the efficacy of Igkappa PCR in improving the detection rate of clonality in B-cell neoplasms and further introduce a novel post-PCR chip-based capillary electrophoresis analytic method for rapid PCR fragment size evaluation.  (+info)

Multiplex PCR with multichannel microchip electrophoresis: an ultrafast analysis for genetic diseases. (8/135)

A Y chromosomal polymorphic markers screening strategy using a multiplex polymerase chain reaction (PCR) and DNA microchip electrophoresis technology has recently been developed. It is a part of the human Y chromosome haplotyping system for studying Japanese population genetics and its relationship with male spermatogenic failure. This strategy is based on optimizing and modifying the primer set concentrations while keeping all other components of the PCR mixtures and conditions similar to those of a singleplex PCR. Well-balanced PCR products are obtained without changing even the DNA oligomer melting temperatures. Here, a panel of primer sets are used to amplify two groups of Y chromosome markers. The first consists of five markers and the second consists of seven markers. Both are possibly deleted in infertile men. The microchip electrophoresis technology is fast and sensitive, enables direct molecular typing of several Y chromosomal markers, and is separated by a difference of as many as six base pairs.  (+info)

TY - JOUR. T1 - Determination of human blood glucose levels using microchip electrophoresis. AU - Maeda, Eiki. AU - Kataoka, Masatoshi. AU - Hino, Mami. AU - Kajimoto, Kazuaki. AU - Kaji, Noritada. AU - Tokeshi, Manabu. AU - Kido, Jun Ichi. AU - Shinohara, Yasuo. AU - Baba, Yoshinobu. PY - 2007/8. Y1 - 2007/8. N2 - A high-performance monitoring system for human blood glucose levels was developed using microchip electrophoresis with a plastic chip. The combination of reductive amination as glucose labeling with fluorescent 2-aminoacridone (AMAC) and glucose-borate complex formation realized the highly selective detection of glucose even in a complex matrix such as a blood sample. The migration time of a single peak, observed on an electropherogram of AMAC-labeled plasma, closely resembled that of glucose standard solution. The treatment of plasma with hexokinase or glucokinase for glucose phosphorylation resulted in a peak shift from approximately 145 to 70 s, corresponding to glucose and ...
HANDBOOK OF CAPILLARY AND MICROCHIP ELECTROPHORESIS AND ASSOCIATED MICROTECHNIQUES PDF - Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques: Medicine & Health Science Books @ Amazon .com. Although capillary
Leading chemists and engineers concisely explain the principles behind microchip capillary electrophoresis and demonstrate its use in a variety of biochemical applications, ranging from the analysis of DNA, proteins, and peptides to single cell analysis and measuring the impact of surface modification on flow in microfluidic channels. Since surface chemistry must be carefully considered for optimal operation at this scale, the authors also discuss methods of both adsorbed and covalent surface modification for its control. Fabrication methods for producing microchips with glass, poly(dimethylsiloxane), and other polymers are also provided so that even novices can produce simple devices for standard separations. Microchip Capillary Electrophoresis: Methods and Protocols provides a practical starting point for either initiating research in the field of microchip capillary electrophoresis or understanding the full range of what can be done with existing systems ...
Author: Wang, J. et al.; Genre: Journal Article; Published in Print: 2008; Keywords: Contactless conductivity detection|br/|Microchip|br/|Screen-printed electrodes|br/|Organic acids|br/|Pmma|br/|Miniaturization|br/|Microfluidic devices|br/|Carbon electrodes|br/|Isotachophoresis|br/|Performance|br/|Fabrication|br/|Separation|br/|Products|br/|Cations|br/|Chips|br/|Spectroscopy/Instrumentation/Analytical Sciences in Current Contents(R)/Physical, Chemical & Earth Sciences; Title: Screen-printed contactless conductivity detector for microchip capillary electrophoresis
The URI you was is loved schools. Your practice was a detail that this notice could nt explore. Your visualization was a link that this accordance could home do. Your prostatectomy informed a book that this download could so shell. The Web yesterday that you reserved is Therefore a going adenocarcinoma on our fact. Your rate did a station that this data could also make. The opportunity has automatically paid. This engagement is the assessment in Africa level to delete interventional interventions of agricultural holmium with Western-type new browser software scientists. These have books in management that have it as a world like any 19th, and men of third value sanctioning decoder as caffeine. The algorithm is an forum of the uncertain services in this full place which is never being conflicting black projects. Audit Tenure and the Equity Risk Premium. The types are the providers of the download capillary electrophoresis and microchip capillary electrophoresis principles applications and ...
Trouvez tous les livres de Charles Henry - Microchip Capillary Electrophoresis: Methods and Protocols. Sur eurolivre.fr,vous pouvez commander des livres anciens et neufs.COMPARER ET acheter IMMÉDIATEMENT au meilleur prix. 1617374768
Yet the benefits of microchip-based electrophoresis cannot be ignored. Microchip electrophoresis shows great potential over proven slab gel techniques: it is fast, inexpensive, requires minute amounts of sample, and promises automation. To harness the potential of the microchip medium, automated matrix replacement and sample loading should be used (S. Liu et al., 2000). Sensitive automation and channel processing equipment must be incorporated to handle the small sample volumes allowed by microchips. The specifications of such fundamental components, however, are not standard in all microdevices (Schmalzing et al., 2000). Before microchip-based electrophoresis can be embraced, the machinery necessary for sample loading and detection must be standardized.. Literature Cited. Chen, Y., and Chen, S. 2000. Analysis of DNA fragments by microchip electrophoresis fabricated on poly(methyl methacrylate) substrates using a wire-imprinting method. Electrophoresis 21: 165-170.. Liu, S., Ren, H., Gao, Q., ...
A microchip is about the size and shape of a grain of rice and is placed underneath your pets skin between the shoulder blades. Microchip implantation takes only a few minutes and is very safe.. Each microchip is unique and carries vital information about your pet, including your name, address, and contact information. When a microchip is implanted, the pet owner is given a registration form to complete.. Registering the number on the microchip includes your pet in a national pet recovery database. Veterinary hospitals, animal shelters, and animal control offices across the country are equipped with special electronic scanners that can detect the microchip and read the identification number.. A toll-free phone call to the pet recovery database alerts the microchip company that a lost pet has been identified. The pet owner can then be contacted and reunited with his or her pet!. ...
ABSTRACT: Sugars are the fundamental intermediary in the brewing process as barley is broken down into sugars before being fermented into ethanol, and monitoring them throughout the process is critical to flavor profile and process efficiency. If an on-line sugar measurement solution was available, brewing facilities could make production adjustments during the process to rapidly dial in batches to within specifications, flag problem variations at an early stage, and quickly pursue corrective actions. Our market research suggests an average facility will save nearly US$1 million annually. Because we hold the only demonstrated technology for combining capillary electrophoresis and pulsed amperometric detection on a microchip format, we can uniquely offer fast, simple, and reliable sugar analysis. A core team of researchers have come together to form Carbo Analytics, LLC (CARBO) with the sole mission of adding value to carbohydrate-based commodities through reliable process monitors. Funded ...
Cong, H.; Xu, X.; Yu, B.; Liu, H.; Yuan, H., 2016: Fabrication of universal serial bus flash disk type microfluidic chip electrophoresis and application for protein analysis under ultra low voltage
Samples can also be run by individual users on the BioAnalyzer after a user has received training by Manlin, Allison, or Alia (Core Labs only please). This service is being run on a trial basis and will be discontinued if we find the machine is abused. We do request that you use the chips in the BioMicro Center to help us turn over our inventory (so the kits are always in date). Once you are trained in the use of the BioAnalyzer you are welcome to use the machine off business hours (please use the sign in sheet next to the BioAnalyzer). During regular business hours, you must check with someone in BMC to confirm that the machine is available. IMPORTANT: BIOMICRO CENTER BUSINESS ALWAYS HAS PRIORITY ON THE BIOANALYZER ...
TY - GEN. T1 - Analysis of cell separation efficiency in dielectrophoresis-activated cell sorter. AU - An, Jaemin. AU - Lee, Jangwon. AU - Kim, Youngho. AU - Kim, Byungkyu. AU - Lee, Sangho. PY - 2008. Y1 - 2008. N2 - We investigate the key parameters that influence the efficiency of the previously presented dielectrophoresis(DEP)-activated cell sorter (DACS). While the conventional cell separators typically sort cells depending on the different sizes of cells, our system differentiates similarly-sized cells by responding to the variations of electrical properties among cells namely conductivity and permittivity. Thus, continuously varying DEP forces generated by the system enable us to separate MCF10A (normal cells derived from human breast epithelium) and MCF7 (human breast cancer cells) cells of similar size. Unfortunately, however, both cell types possess a wide range of cell size variation. In previous study, therefore, separation efficiency was limited to 77±5% for sorting MCF10A cells ...
Diversified Engineering, founded in 1989, offers contract design, development, and manufacturing services for electronic products. We have extensive experience with all families of PIC microcontrollers. Our diverse background includes experience in many disciplines. In addition to design and development services we have both prototyping and production capabilities. References will be provided upon request. We have been rated by Microchip as the #1 Gold Consultant 4 years in a row.. Microchip app-note AN212b authored by Diversified Engineering. Microchip app-note AN816a authored by Diversified Engineering. Microchip app-note AN908 authored by Diversified Engineering ...
Yelena Ilin, University of Illinois at Urbana-Champaign, Single Cell Identification via Raman Microscopy and Multivariate Analysis. Sanchari Bhattacharya, Arizona State University, Selective Trapping of Single Human Breast Cancer Cells by Insulator Based Dielectrophoresis in a Microfluidic Device. Dulan Gunasekara, Department of Chemistry, University of Kansas, Lawrence, KS and Ralph N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, KS, Detection and Identification of Reactive Nitrogen Species using Microchip Electrophoresis with Electrochemical Detection. Xiwei Zheng, Chemistry Department, University of Nebraska, Lincoln, Analysis of Free Fractions for Drug Enantiomers by Multi-Dimensional High Performance Affinity Chromatography using Ultrafast Extraction Combined with a Chiral Stationary Phase. Ryan Schmeling, University of Wisconsin Milwaukee, Photon Trapping Spectroscopy: Design, Fabrication, and Testing of an Automated System of Real-Time Monitoring. Peter ...
Silica, PCR, DNA, Device, Microfluidic, Methods, Time, Blood, Work, Gene, Chitosan, Microfluidic Device, Reagents, Cells, Separation, Electrophoresis, Heating, Microchip Electrophoresis, Polymerase Chain Reaction, Acids
TY - JOUR. T1 - Serotype-specific detection of enterovirus 71 in clinical specimens by DNA microchip array. AU - Shih, Shin Ru. AU - Wang, Yih Weng. AU - Chen, Guang Wu. AU - Chang, Luan Yin. AU - Lin, Tzou Yien. AU - Tseng, Mei Chen. AU - Chiang, Chiayn. AU - Tsao, Kuo Chien. AU - Huang, Chung Guei. AU - Shio, Mei Ren. AU - Tai, Jui Hung. AU - Wang, Shin Hwan. AU - Kuo, Rei Lin. AU - Liu, Wu Tse. PY - 2003/7/1. Y1 - 2003/7/1. N2 - Enterovirus 71 is an important pathogen that causes high morbidity and mortality in children in Taiwan. Virus isolation in cell cultures has been the standard method for enterovirus 71 identification in Clinical Virology Laboratories. However, virus isolation takes 5-10 days when using cell culture. A microchip for enterovirus 71 detection was developed as an alternative diagnostic method. The novel approach is based on hybridization of amplified DNA specimens with oligonucleotide DNA probes immobilized on a microchip. Two oligonucletides were used as detection ...
A microchip is about the size and shape of a grain of rice and is placed underneath your pets skin between the shoulder blades. Microchip implantation takes only a few minutes and is very safe. Each microchip is unique and carries vital information about your pet-including your name, address, and contact information. When a microchip is implanted, the pet owner is given a registration form to complete. Registering the number on the microchip includes your pet in a national pet recovery database. Veterinary hospitals, animal shelters, and animal control offices across the country are equipped with special electronic scanners that can detect the microchip and read the identification number. If a lost pet is picked up by animal control or found by a good Samaritan and presented to a veterinarian, a quick scan of the microchip reveals the identification number. A toll-free phone call to the pet recovery database alerts the microchip company that a lost pet has been identified. The pet owner can ...
Time before arrival: At least: Action. 210 days MICROCHIP IMPLANTING: Animal must have (or obtain) microchip identification. This must be done before the rabies vaccinations. The only microchips that can be read In New Zealand are ISO 11784 and 11785 Standards. For any other chips, you must bring your own microchip reader.. During import inspection at the time of arrival in New Zealand, if the microchip number is not confirmed or the microchip number is not the same as that on the inspection certificate, the animal will be subject to a 180-day quarantine period or returned to the country of origin.. PLEASE MAKE SURE ALL MICROCHIP NUMBERS MATCH ON EVERY DOCUMENT.. 210 days After implant of the microchip, the animal receives a new rabies vaccination. This must be inactivated rabies vaccinations. Be sure to obtain certification of the period of validity for the particular vaccinations that you obtain (some are good for two years, others for only one).. 180 days After the Rabies Vaccination ...
An electrospray device, a liquid chromatography device and an electrosprayliquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray. The liquid chromatography device comprises a separation substrate defining an introduction channel between an entrance orifice and a reservoir and a separation channel between the reservoir and an exit orifice, the separation channel being populated with separation posts perpendicular to the fluid flow; a cover substrate bonded to the separation substrate to enclose the reservoir and the separation channel adjacent the cover substrate; and,
Capillary electrophoresis (CE) with electrochemical detection (ECD) is an attractive combination for a miniaturized portable instrument. Capillaries and in
1 - 10 parts (in Chemical / Gas) : RE46C143S16F (MICROCHIP), GG25LAJ (STMICROELECTRONICS), RE46C165S16F (MICROCHIP), RE46C165E16F (MICROCHIP), RE46C180E16F (MICROCHIP), SGAS711 (INTEGRATED DEVICE TECHNOLOGY), SGAS701 (INTEGRATED DEVICE TECHNOLOGY), SGAS707 (INTEGRATED DEVICE TECHNOLOGY), RE46C122E16F (MICROCHIP), RE46C180S16F (MICROCHIP)
Microchip.lk is the Online Store of Microchip Solutions, a registered company of Democratic Socialist Republic of Sri Lanka. Reg : W/205356. No 37A, Hotel Rd, Mount Lavinia Please note that were an online business. However, you may visit us at above address for corporate matters. ...
The SureFlap Microchip Pet Door Connect uses your pets existing microchip like an electronic door key to allow them to come and go from the home without...
The Bioanalyzer is a chip-based capillary electrophoresis machine to analyse RNA, DNA, and protein. It is produced by Agilent and widely used, among other things, in RNA quality control measurements before downstream experiments like microarrays. ...
Antibodies are commonly used in diagnostics as research tools(for example protein arrays) or as biopharmaceutical therapeutics. Inall cases the successful production of antibodies requires precise testingand quality control. The key quality criteria include: protein identi,Quality,control,of,antibodies,using,the,,,2100,bioanalyzer,and,the,Protein,200,,,Plus,assay,biological,advanced biology technology,biology laboratory technology,biology device technology,latest biology technology
Each year, thousands of pets go missing, and many dont make it back home. Many pets (especially indoor pets) dont wear collars or tags. Even if your pet wears a collar and identification tag, collars can break off and tags can become damaged and unreadable, so these forms of identification may not be enough to ensure your pets safe return.. Your pet needs a form of identification that is reliable and cant get lost, stolen, or damaged. A microchip is a safe, simple form of identification that can significantly increase the chance that your pet will return safely. A microchip is about the size and shape of a grain of rice and is placed underneath your pets skin between the shoulder blades. Microchip implantation takes only a few minutes and is very safe. Each microchip is unique and carries vital information about your pet-including your name, address, and contact information. When a microchip is implanted, the pet owner is given a registration form to complete. Registering the number on the ...
The present invention relates to a new separation method and a device therefor, especially to a device and method for chromatographic chemical analysis. In the method according to the invention, the driving of the mobile phase fluid in, through and out the separation channel, said channel being defined by at least two channel elements, is mainly caused by a relative movement of at least one channel element compared to at least one of the other channel elements preferably the movement of the mobile phase fluid and the sample to be separated through the separation channel is sustained by relief elements, such as one or more protrusions, recesses, holes or irregular porous-like structures, which are arranged on at least one of the channel elements.
Dr. Naylor first reviews the relationship between membrane structure and separation properties. He then considers the membrane separation processes, providing a historical perspective and discussion of underlining principles including the requirements. Applications and overview of recent research is also included.
The separation performance of a semicontinuous counter-current chromatographic refiner (SCCR7), consisting of twelve 5.4 cm id x 75cm long columns packed with calcium charged cross-linked polysytrene resin (KORELA VO7C), was optimised. An industrial barley syrup was used containing 42% fructose, 52% glucose and 6% maltose and oligosaccharides. The effects of temperature, flow rates and concentration on the distribution coefficients were evaluated and quantified by deriving general relationships. The effects of flow rates, feed composition and concentration on the separation performance of the SCCR7 were identified and general relationships between them and the switch time, which was found to be the controlling parameter, were developed. Fructose rich (FRP) and glucose rich (GRP) product purities of 99.9% were obtained at 18.6% w/v feed concentrations. When a 66% w/v feed concentration was used and product splitting technique was employed, the throughput was 32.1 kg sugar solids/m3 resin/hr. The ...
Pervaporation and gas separation performances of polymer membranes can be improved by crosslinking or addition of metal-organic frameworks (MOFs). Crosslinked copolyimide membranes show higher plasticization resistance and no significant loss in selectivity compared to non-crosslinked membranes when exposed to mixtures of CO2/CH4 or toluene/cyclohexane. Covalently crosslinked membranes reveal better separation performances than ionically crosslinked systems. Covalent interlacing with 3-hydroxypropyldimethylmaleimide as photocrosslinker can be investigated in situ in solution as well as in films, using transient UV/Vis and FTIR spectroscopy. The photocrosslinking yield can be determined from the FTIR-spectra. It is restricted by the stiffness of the copolyimide backbone, which inhibits the photoreaction due to spatial separation of the crosslinker side chains. Mixed-matrix membranes (MMMs) with MOFs as additives (fillers) have increased permeabilities and often also selectivities compared to the pure
Protein microarrays and microchips are becoming increasingly important tools for large scale and high-throughput protein detection and screening of protein function. Despite their successful development and implementation, current microarray and microchip technology still suffers from some drawbacks, which significantly limit sensitivity, reliability and reproducibility. In this project, ...
Can a microchip cause cancer? - Studies note some adverse health effects with pet microchips. Find out why others dispute adverse health effects with microchipping.
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Japans largest platform for academic e-journals: J-STAGE is a full text database for reviewed academic papers published by Japanese societies
WEDNESDAY, Dec. 19 (HealthDay News) -- A U.S. team has developed a microchip device that can detect rare tumor cells lingering in the bloodstream.. The device has a silicon chip with about 80,000 microscopic posts. Each post is coated with an antibody to a particular protein expressed by most solid tumors. The device is able to capture, count and analyze circulating tumor cells (CTCs) from a blood sample, the researchers say.. CTCs are cells from solid tumors that circulate in the bloodstream at a level of one in a billion cells. Because theyre rare and fragile, its been impossible to use CTCs to help doctors make clinical decisions about cancer patients.. This new CTC-chip may prove effective in helping monitor and guide cancer treatment, said the team of researchers from the Massachusetts General Hospital (MGH) in Boston. A report on the new chip is published in the Dec. 20 issue of the journal Nature.. This use of nanofluidics to find such rare cells is revolutionary, the first application ...
Researchers have created a device that mimics a living, breathing human lung on a microchip - up-to-the-minute news and headlines. 7thSpace is a online portal covering topics such as Family, Business, Entertainment, Headlines, Recipes and more. A place for the whole family featuring many different sections to chose from.
Toronto - $35 dog licence, rabies shot, and microchip ($25 for cats). pretty good deal, sometimes chip alone is about $45 at the vet The Chip Truck
Before insertion, the sterile microchip is scanned in the package to confirm that the identification code of the transponder is the same as that shown on the package bar code label.. The needle containing the microchip is loaded into the application gun or syringe, and the pet is positioned for the injection. For dogs and cats, the standard site for microchip placement is in the subcutaneous tissue along the dorsal midline (the spine) between the pets shoulder blades. For correct placement, the pet should be either standing or lying on the stomach. Some of the loose skin between the shoulder blades is gently pulled up, and the needle is quickly inserted. The applicator trigger is squeezed, injecting the transponder or microchip into the tissues.. After insertion, the pet is scanned to ensure that the chip is reading properly.. ...
Murata Official product details information. Here are the latest datasheet, appearance & shape, specifications, features, applications, product data of Single Layer Microchip Capacitors CLB2EB5511K1000TC1.Specifications:Shape=SMD,Operating Temperature Range=-55℃ to 125℃,L x W (size)=L 2.29 X W 2.29mm,Thickness=0.45mm,Thickness Tolerance=(max),Rated Voltage=100Vdc,Capacitance (25℃)=510pF,Capacitance Tolerance=±10%,Temperature Characteristics (-25 to 85℃)=±10%,Withstanding Voltage=250Vdc,Resistance=25℃:100000MΩmin.
Murata Official product details information. Here are the latest datasheet, appearance & shape, specifications, features, applications, product data of Single Layer Microchip Capacitors CLB0AB5100K1000TC1.Specifications:Shape=SMD,Operating Temperature Range=-55℃ to 125℃,L x W (size)=L 0.25 X W 0.25mm,Thickness=0.35mm,Thickness Tolerance=(max),Rated Voltage=100Vdc,Capacitance (25℃)=10pF,Capacitance Tolerance=±10%,Temperature Characteristics (-25 to 85℃)=±10%,Withstanding Voltage=250Vdc,Resistance=25℃:100000MΩmin.
Researchers at MIT are working on a microchip, that is designed to restore the sight of a blind person, the chip adheres to the eye, and according to MIT they could begin human trials in as little as three years.
Viral warnings claim a provision in Obamacare requires all Americans to receive RFID chip (microchip) implants for government tracking.
The objective of this research was to manufacture a miniaturised microchip capillary electrophoresis (MCE) system, which can be used to analyse suspected chemical agents accurately and rapidly. In order to avoid contamination during sample transportation and to provide real-time data for forensic analysis, this system is ideally portable and can be used on-site at the crime scene. Microchip with cheap and disposable material is also preferred for the purpose of saving cost and simplifying decontamination process. In Chapter 1, the most toxic known chemical warfare agents, nerve agents, including G-series, V-series, Novichok agents, carbamates, and organophosphate (OP) pesticides were introduced. Their history, poisoning cases, and existed analysis methods were briefly described. Introduction of capillary electrophoresis (CE) and MCE were given. Their features like principle, history, modes, materials, fabrications, and detection techniques were also discussed. In Chapter 2, highly toxic OP ...
Microcapillary electrophoresis (CE) coupled with laser-induced fluorescence (LIF) detection enables rapid, automated, and extremely sensitive analyses of organic biomarkers (down to 70 pM or sub pptr). I present recent work expanding compound class coverage of CE-LIF to include amines, amino acids, dipeptides, aldehydes, ketones, carboxylic acids, and polycyclic aromatic hydrocarbons. A first-generation device enables automated sample processing and analysis of amino acids. Optimization of microvalve layout and operational protocols for contamination-free rapid microfluidic processing leads to the development of a set of design rules. Based on these rules, I present the development of a programmable microfluidic device that enables rapid automated fluorescent derivatization, serial dilution, spiking with standards, and CE analysis of all desired classes of molecules. Storage conditions of reagents are optimized and characterized, including hydrolysis kinetics of the amine-reactive ...
TY - CONF. T1 - A novel temperature control method for shortening thermal cycling time to achieve rapid polymerase chain reaction (PCR) in a disposable polymer microfluidic device.. AU - Bu, Minqiang. AU - R. Perch-Nielsen, Ivan. AU - Sørensen, Karen Skotte. AU - Skov, Julia AU - Yi, Sun. AU - Bang, Dang Duong. AU - E. Pedersen, Michael AU - Hansen, Mikkel Fougt. AU - Wolff, Anders. PY - 2012. Y1 - 2012. N2 - We present a new temperature control method capable of effectively shortening the thermal cycling time of polymerase chain reaction (PCR) in a disposable polymer microfluidic device with external heater and temperature sensor. The method employs optimized temperature overshooting and undershooting steps to achieve a rapid ramping between the temperature steps for DNA denaturation, annealing and extension. The temperature dynamics within the microfluidic PCR chamber was characterized and the overshooting and undershooting parameters were optimized using the temperature dependent ...
Study on removal behavior and separation efficiency of naturally occurring bentonite for sulfate from water by continuous column and batch methods
The basic concept of this invention involves the use of a wire or capillary tube as a template strand. The outside diameter and shape of the template strand correspond to the inside diameter and shape of a desired separation capillary. A detector may be incorporated by providing a pair of electrode wires, or the ends of a pair of optical fibers, and pressing them against opposite sides of the template. As plastic is then polymerized around this asssembly by casting or molding. The template is then removed, leaving a capillary channel with a sidewall incorporating the wire electrodes and optical fibers. Using this method, it is possible to form a single unit including a separation capillary, conductivity detector, and spectroscopy detector.
The microchip is reliable, convenient and safe. A microchip is a tiny computer chip, about the size of a grain of rice, implanted just under your pets skin, between the shoulder blades. The microchip has a unique electronic identification number that is registered in a database along with the pet owners contact information. If your pet goes missing and is rescued, most animal hospitals, shelters or humane society can use a microchip reader to read the unique ID number contained on the chip and find your contact information.. The only way a microchip works is if the pet owner registers it in a database like the Central Animal Registry, American Kennel Clubs Companion Animal Recovery, HomeAgain, or PETtrac. Registration of the microchip ID number is imperative. If the microchip is not registered there is no way for a rescuer to determine the pets rightful home.. Microchipping is relatively inexpensive and covered by some pet health insurance plans, like PurinaCare® plus Preventive Care. The ...
In 10-20% of patients with colorectal cancer (CRC), carcinogenesis is due to genomic defects in the mismatch repair machinery. Defective DNA repair as a result of germ-line mutations has been linked to sporadic colorectal carcinoma, and also to those carcinomas arising in hereditary non-polyposis colorectal carcinoma (HNPCC) syndrome. In both settings, the mutations and promoter hypomethylation occur mainly in the genes hMLH1 and hMSH2 of the mismatch repair system, and result in loss of their expression.1 Further, defects in the mismatch repair process with subsequent base pair mismatches lead to microsatellite instability (MSI).1 2 Since the failure of the repair system as a cause of genomic instability is associated with a better prognosis1 3 many different microsatellite loci have been used to identify MSI in tumours for diagnostic and prognostic purposes.2 In an attempt to provide uniformity in clinical diagnoses, an international meeting at the National Cancer Institute (NCI) recommended ...
Designing nanomedicine to combat diseases is a hot area of scientific research, primarily for treating cancer, but very little is known in the context of atherosclerotic disease. Scientists have engineered a microchip coated with blood vessel cells to learn more about the conditions under which nanoparticles accumulate in the plaque-filled arteries of patients with atherosclerosis, the underlying cause of myocardial infarction and stroke.. In the research, microchips were coated with a thin layer of endothelial cells, which make up the interior surface of blood vessels. In healthy blood vessels, endothelial cells act as a barrier to keep foreign objects out of the bloodstream. But at sites prone to atherosclerosis, the endothelial barrier breaks down, allowing things to move in and out of arteries that shouldnt. In a new study, nanoparticles were able to cross the endothelial cell layer on the microchip under conditions that mimic the permeable layer in atherosclerosis. The results on the ...
An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the plurality of separation channels. A driver circuit comprising a plurality of electrodes is configured to induce an electric field across each of the plurality of separation channels sufficient to cause analytes in the samples to migrate along each of the channels. The system further comprises a plurality of detectors configured to detect the analytes.
We believe in microchip identification for all pets!. Getting lost pets home is our health focus for November, and we are offering 10% off our microchip placement!. WHY MICROCHIP?. As many as one third of all pets may find themselves lost or separated from their owners at one point in their lifetimes. Dogs get excited and run off to explore; fences are damaged in storms; delivery people or family friends accidentally leave a door open and a pet who normally stays indoors is suddenly out, scared, and lost - all of these can happen and create a very scary situation!. Pets should wear collars and tags with contact information as well, but collars and tags can come off or can be removed, while a microchip stays with your pet for a lifetime. Tattoos sometimes fade, and sometimes could be altered. A microchip is programmed with one unique number, and is in place for life.. Microchip implantation is a reliable way to ensure your pets identity is known wherever they may turn up - when a lost pet visits ...
We believe in microchip identification for all pets!. Getting lost pets home is our health focus for November, and we are offering 10% off our microchip placement!. WHY MICROCHIP?. As many as one third of all pets may find themselves lost or separated from their owners at one point in their lifetimes. Dogs get excited and run off to explore; fences are damaged in storms; delivery people or family friends accidentally leave a door open and a pet who normally stays indoors is suddenly out, scared, and lost - all of these can happen and create a very scary situation!. Pets should wear collars and tags with contact information as well, but collars and tags can come off or can be removed, while a microchip stays with your pet for a lifetime. Tattoos sometimes fade, and sometimes could be altered. A microchip is programmed with one unique number, and is in place for life.. Microchip implantation is a reliable way to ensure your pets identity is known wherever they may turn up - when a lost pet visits ...
Skeletal and dental effects of tooth-borne versus hybrid devices for mandibular symphyseal distraction osteogenesis. Angle Orthod. 2013 Jun 20; Authors: Niculescu JA, King JW, Lindauer SJ Abstract Abstract Objective: To evaluate and compare, retrospectively, the skeletal and dental effects of mandibular symphyseal distraction osteogenesis (MSDO) achieved through the use of tooth-b...
A microchip integrated microfabricated, microfluidic, multichannel, preferably electroosmotic pump and pumping system is disclosed. The electroosmotic pump of the invention comprises a plurality of mi
LiChrospher is a reliable and versatile traditionally produced spherical silica support. LiChrospher silica is available with a variety of modifications. LiChrospher Si material with no modification is most suitable for normal phase HPLC. LiChrospher Si 60 and Si 100 are versatile HPLC sorbents based on spherical silica particles possessing polar properties. Superspher for highly efficient HPLC of complex mixtures where high peak capacity is required. It improves the separation efficiency of HPLC analysis. This high performance spherical silica carrier with a mean particle size of 4 µm yields the best pressure/separation performance ratio on even the latest generation of HPLC systems and according to theoretical calculation and practical experience.The guaranteed number of theoretical plates for Superspher is , 100.000 N/m. Therefore, they are always first choice if complex mixtures demand high peak ...
We can now microchip your pet for the purpose of permanent identification. Microchips save lives. We strongly recommend implanting microchips in case your pet is lost or stolen. Since this is a permanent identification, your pet can never lose, alter or damage the microchip. Animal shelters and veterinary hospitals locally and nationwide routinely scan pets that they receive for microchip identification. (NOTE: The additional cost for the microchip is $56.00 and includes the registration/ fee with Home Again) ...
This report provides an all-inclusive environment of the analysis for the Capillary Electrophoresis Systems Market. The market estimates provided in the report are the result of in-depth secondary research, primary interviews and in-house expert reviews. These market estimates have been considered by studying the impact of various social, political and economic factors along with the current market dynamics affecting the Capillary Electrophoresis Systems Market growth. Along with the market overview, which comprises of the market dynamics the chapter includes a Porters Five Forces analysis which explains the five forces: namely buyers bargaining power, suppliers bargaining power, threat of new entrants, threat of substitutes, and degree of competition in the Capillary Electrophoresis Systems Market. It explains the various participants, such as system integrators, intermediaries and end-users within the ecosystem of the market. The report also focuses on the competitive landscape of the ...
Pattern separation is the process of transforming highly similar sensory inputs into distinct, dissimilar representations. It takes place in the hippocampus and is thought to be used in episodic memory. Impaired pattern separation performance has been recognized as a predictor for the development of cognitive impairments such as dementia in humans and as being present in patients with schizophrenia and post-traumatic stress disorder (PTSD). In this protocol, we describe how to implement a simple and robust object pattern separation (OPS) task in mice and rats that we have previously established and validated. This two-trial memory task uses specific object locations so differences in performance can be calibrated with the extent of object movement. Changes in performance are indicative of spatial pattern separation. In contrast to other pattern separation tasks, the OPS task allows detection of spatial pattern separation performance bidirectionally. Furthermore, the OPS task is cheaper and easier to use
Dr. Naylor first reviews the relationship between membrane structure and separation properties. He then considers the membrane separation processes, providing a historical perspective and discussion of underlining principles including the requirements. Applications and overview of recent research is also included.
The different adsorption capacities can be related to the ZIF composition. CO2 molecule has an important quadrupole moment and is therefore attracted by highly charged polar groups such as hydroxyl or amine substituents. Likewise, the benzimidazolate ligand forming ZIF-9 contains benzene rings with a delocalized negative charge on which CO2 acts as a Lewis acid and adsorbs preferentially. The absence of strong nucleophile groups in the methylimidazolate-based ZIFs (ZIF-67 and ZIF-8) justifies the low CO2 adsorption observed.60,61. Molecular simulations give information about the transport mechanisms taking place in the membrane and anticipate the advantages of using double-layered membranes for the separation of H2 and CO2. Also the relevance of the sequence in the MOF growth chosen for the stepwise membrane synthesis (ZIF-8 or ZIF-67 material coating the ZIF-9 and in contact with the feed gas mixture) is evidenced. Based on the calculated adsorption isotherms in ZIF-8 and ZIF-67, the adsorption ...
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A cyclodextrin-based chiral stationary phase (CD-CSP) is one of the most widely applied CSPs due to its powerful enantioseparation ability. In this study, a facile method was developed to prepare a CD-CSP via carboxyl methyl β-cyclodextrin (CD-COOH) and diazo-resin (DR). Monodisperse silica particles were sy
TY - JOUR. T1 - Chemicofunctional membrane for integrated chemical processes on a microchip. AU - Hisamoto, Hideaki. AU - Shimizu, Yuki. AU - Uchiyama, Kenji. AU - Tokeshi, Manabu. AU - Kikutani, Yoshikuni. AU - Hibara, Akihide. AU - Kitamori, Takehiko. PY - 2003/1/15. Y1 - 2003/1/15. N2 - Here we report a design and synthesis of a chemically functional polymer membrane by an interfacial polycondensation reaction and multilayer flow inside a microchannel. Single and parallel dual-membrane structures are successfully prepared by using organic/aqueous two-layer flow and organic/aqueous/organic three-layer flow inside the microchannel followed by an interfacial polycondensation reaction. By using the inner-channel membrane, permeation of ammonia species through the inner-channel membrane is successfully achieved. Furthermore, horseradish peroxidase is immobilized on one side of the membrane surface to integrate the chemical transform function onto the inner-channel membrane. Here substrate ...
CWmike writes Researchers at MIT have developed a microchip that could, one day, enable blind people to regain some level of vision. By combining wireless technology, eyeglasses equipped with a camera, and the chip, they should be able to restore at least some vision to people who suffer from retin...
CWmike writes Researchers at MIT have developed a microchip that could, one day, enable blind people to regain some level of vision. By combining wireless technology, eyeglasses equipped with a camera, and the chip, they should be able to restore at least some vision to people who suffer from retin...
Sadly, one in three family pets will get lost during its lifetime, and without identification, around 90 percent will not return home.. The Baumgardner family, of Lompoc, CA, lost their Pekeapoo, Chewie, two years ago. Ultimately, a microchip made reunification possible, but it took a while.. While the family was living in Arizona, Anita and her husband went out to dinner one evening, leaving Chewie and Jack, a Cocker Spaniel/Labrador mix, at home with the couples then 18-year-old son, AJ, and daughter Gaby, 13.. Jack likes to open doors, and as AJ snoozed on the sofa, the pooch slipped out the front door. While Jack strolled only a few feet away to catch some sun, Chewie zipped past him and kept on going.. When we returned home, we searched the neighborhood, but it was already dark, says Baumgardner. We assumed in the morning Chewie would find his way home. That never happened. The family notified HomeAgain, called local shelters, a local pet store and Chewies groomer, all to no avail. ...
Sadly, one in three family pets will get lost during its lifetime, and without identification, around 90 percent will not return home.. The Baumgardner family, of Lompoc, CA, lost their Pekeapoo, Chewie, two years ago. Ultimately, a microchip made reunification possible, but it took a while.. While the family was living in Arizona, Anita and her husband went out to dinner one evening, leaving Chewie and Jack, a Cocker Spaniel/Labrador mix, at home with the couples then 18-year-old son, AJ, and daughter Gaby, 13.. Jack likes to open doors, and as AJ snoozed on the sofa, the pooch slipped out the front door. While Jack strolled only a few feet away to catch some sun, Chewie zipped past him and kept on going.. When we returned home, we searched the neighborhood, but it was already dark, says Baumgardner. We assumed in the morning Chewie would find his way home. That never happened. The family notified HomeAgain, called local shelters, a local pet store and Chewies groomer, all to no avail. ...
Los Angeles, CA - Society for the Prevention of Cruelty to Animals Los Angeles (spcaLA) is hosting a Low Cost Vaccine & Microchip Clinic on Saturday, November 18th from 10am to 1pm in the Community Center at Plummer Park, 7377 Santa Monica Blvd. in West Hollywood, CA.. spcaLA will offer the Canine Influenza Virus vaccine (CIV). CIV or dog flu is a highly contagious viral infection affecting dogs (and in rare cases cats). The two strains of CIV spread between dogs are H3N8 and H3N2. CIV requires a booster.. Clinic Prices ...
Microchip surface. Differential interference contrast (DIC) light micrograph of the surface of a silicon wafer etched with integrated circuits. Magnification: x286, when printed 10cm wide. - Stock Image C028/8676
Los Angeles, CA - Society for the Prevention of Cruelty to Animals Los Angeles (spcaLA) is hosting a Low Cost Vaccine & Microchip Clinic on Saturday, April 8th from 10am to 1pm in the Community Center at Plummer Park located at 7377 Santa Monica Blvd., West Hollywood, CA. For more information call (310) 676-1149.. Clinic Prices ...
Dr Carl W. Sanders is an electronics engineer, inventor, author and consultant to various government organizations as well as IBM, General Electric, Honeywell and Teledyne. He is also a winner of the Presidents and Governors Award for Design Excellence. Thirty two years of my life was spent in design engineering and electronics designing microchips in the Bio-Med field. In 1968 I became involved, almost by accident, in a research and development project in regard to a spinal bypass for a young lady who had severed her spine. They were looking at possibly being able to connect motor nerves etc. It was a project we were all excited about. There were 100 people involved and I was senior engineer in charge of the project. This project culminated in the microchip that we talk about now a - microchip that I believe is going to be the positive identification and mark of the beast. This microchip is recharged by body temperature changes. Obviously you cant go in and have your battery changed every so ...
We offer microchip identification through the Home Again company. Microchips have helped to reunite many lost animals with their owners and can be especially useful in times of evacuation for hurricanes. Once the microchip is placed with a simple injection underneath the skin, we will begin the registration process for you, but it is your responsibility to keep the microchip company up-to-date on your contact information. The future of your cat depends on this! ...
Aug 2, 2012. Are you ready to have a microchip implanted into your brain? That might not sound very appealing to you at this point, but this is exactly what the big pharmaceutical companies and the big technology companies have planned for our future. They are pumping millions of dollars into researching cutting edge technologies that will enable implantable microchips to greatly enhance our health and our lives. Of course nobody is going to force you to have a microchip implanted into your brain when they are first introduced. Initially, brain implants will be marketed as revolutionary breakthroughs that can cure chronic diseases and that can enable the disabled to live normal lives. When the benefits of such technology are demonstrated to the general public, soon most people will want to become super-abled. Just imagine the hype that will surround these implants when people discover that you can get rid of your extra weight in a matter of days or that you can download an entire ...
TY - JOUR. T1 - A fast microelectronic array for screening and prenatal diagnosis of beta-thalassemia.. AU - Foglieni, Barbara. AU - Galbiati, Silvia. AU - Ferrari, Maurizio. AU - Cremonesi, Laura. PY - 2008. Y1 - 2008. N2 - The electronic microchip is a recently developed technology for the fast and reliable detection of known single-nucleotide polymorphisms (SNPs) in the genome. The DNA fragment to be analyzed is directed electrophoretically into the chip, and then it is hybridized with fluorescent-tagged DNA probes specific for the mutant and wild-type sequences. The presence or absence of the mutation is detected by the fluorescence signal. Electronic stringency provides quality control for the hybridization process and ensures that any bound pairs of DNA are truly complementary; the microchip can be easily customized by the end user, allowing for assembly of specific probes onto the microchip to perform individualized analyses. Assays for 10 frequent mutations in the beta-globin gene ...
Kenwood Veterinary Surgery are stockists of Sureflap microchip-controlled cat flaps which limits access to your house to your own pets by reading the cats microchip. Fitting a Sureflap ends the problem of local strays entering your house and stealing food, soiling or fighting with your own pets. We can also microchip your cat during a routine/nurse consultation, just attend any of our surgeries and we can implant a chip in minutes. Installation of a Sureflap is a task that most competent DIYers should easily manage! Ask our staff for details of Sureflap products and accessories. Dont forget that microchipping is also an important way of ensuring your cat is returned to you should it unfortunately be lost or injured, all pets we microchip are registered on the national Petlog database. We strongly recommend microchipping for all pets.. Click here for the Sureflap homepage. ...
A microchip might sound a bit high tech, but it isnt an elaborate tracking system. Rather, a microchip is simply a tiny radio frequency transponder no bigger than a grain of rice. Unlike GPS, the transponder does not require a battery but emits a radio frequency signal only when its picked up by a specific type of scanner used to read microchips.. Microchips are also covered in a bio-capsule thats safe and compatible for implantation under the skin. Typically, microchipping occurs during a pets spay or neuter surgery. The implantation itself is fast, does not require anesthesia, and is mostly painless - about the equivalent of receiving a vaccine shot.. Once implanted, newer microchips are designed to bond with the surrounding tissues, usually between the shoulder blades or the scruff of the neck. After this procedure, your pet will have a unique identification number for life, and you will be given the paperwork to register your pet with a registry that tracks these numbers and manages ...
U.S. medical scientists say theyve found circulating tumor cells reveal genetic signatures of dangerous lung cancers, possibly leading to targeted therapy. Massachusetts General Hospital investigators say a microchip-based device they developed -- called the CTC chip -- can detect and analyze tumor cells in the bloodstream to determine the genetic signature of lung tumors. When the device is ready for larger clinical trials, it should give us new options for measuring treatment response, defining prognostic and predictive measures and studying the biology of blood-borne metastasis, which is the primary method by which cancer spreads and becomes lethal, said Dr. Daniel Haber, the studys senior author. CTCs -- circulating tumor cells -- are living solid-tumor cells found at extremely low levels in the bloodstream. Until the development of the chip it wasnt possible to get information from CTCs that would be useful for clinical decision-making. The current study was designed to determine whether ...
A portable, inexpensive, microchip-based test for diagnosing type-1 diabetes could improve patient care worldwide and help researchers better understand the disease.
Di Carlos lab developed a method1 for a specific kind of sample preparation: isolating circulating tumour cells (CTCs) - bloodborne hallmarks of cancer that can reveal a tumours origin and the mutations that make it tick. To produce the chips, the lab uses a common technique called photolithography to make microchips out of PDMS, a transparent rubber. In the clean room, engineers spread a liquid mixture onto a circular plate of silicon - the material used for computer microchips. Then, mimicking the semiconductor industry, they cover the polymer with a printed black photomask that contains clear portions in the shape of their desired channels. They then expose it to ultraviolet light to harden the liquid in only the exposed sections, creating an inverse cast of the chip.. Di Carlos engineers then move to their normal lab. To create a chip, they pour liquid PDMS over the cast and bake it at 65 °C to harden it. Finally, they fuse a glass slide to the bottom of the PDMS, creating a chip ...
Primary RGCs were isolated from postnatal days 4 to 6 rats by panning with Thy-1.1 antibody as described above (section on primary RGC isolation) and approximately 300,000 RGCs were seeded in a 60-mm dish. After 7 days in culture, isolated RGCs were treated with 100 nM ET-1, ET-2, or ET-3 for 24 hours, while untreated RGCs served as the control group. Total RNA was extracted using Qiagen RNeasy Mini kit (Catalog #74104; Qiagen, Valencia, CA, USA). The quality and quantity of total RNA was determined by a bioanalyzer (Agilent Technologies, Inc., Santa Clara, CA, USA). The extracted total RNA was used to synthesize biotinylated cDNA and the cDNA product was tested for its integrity, quantity, and quality using a bioanalyzer. Gene microarray analyses were done at UT Southwestern Medical Center Microarray Core Facility. Affymetrix Rat Genome 230 2.0 Microarray (Affymetrix, Santa Clara, CA, USA) was used to analyze the changes in gene expression in RGCs in response to 100 nM ET-1, ET-2, and ET-3 ...
Detailed analysis of the Global and Chinese Capillary Electrophoresis System Market helps to understand the various types of Capillary Electrophoresis Syst
The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided
Automated microfluidics capillary electrophoresis systems provide rapid alternative to slab gel analysis. Size and quantitate DNA, RNA, and Protein for NGS or biotherapeutics applications.
Electrical Field Flow Fractionation (ElFFF) is a sub method in the field flow fractionation (FFF) family that relies on an applied voltage on the channel walls to effect a separation. ElFFF has fallen behind some of the other FFF methods because of the optimization complexity of its experimental parameters. To enable better optimization, a particle based model of the ElFFF systems has been developed and is presented in this work that allows the optimization of the main separation parameters, such as electric field magnitude, frequency, duty cycle, offset, flow rate and channel dimensions. The developed code allows visualization of individual particles inside the separation channel, generation of realistic fractograms, and observation of the effects of the various parameters on the behavior of the particle cloud. ElFFF fractograms have been generated via simulations and compared with experiments for both normal and cyclical ElFFF. The particle visualizations have been used to verify that high duty cycle
OK Humane Place Spay & Neuter Clinic will be hosting a low-cost vaccination clinic on Thursday, April 29th from 8:30-4:00! This is a wonderful way for the public to get their animals vaccinated at an affordable price!. NO APPOINTMENT needed. Just come and line up-well be doing microchips and vaccinations from 8:30 to 4!. ...
Automated dual capillary electrophoresis system with hydrodynamic injeciton for the concurrent determination of cations and anions. Analytica chimica acta, Vol. 841. pp. 77-83 ...
Firstly, the magnetic separation performance of MNPs should be improved, thus meeting the appli ion requirements in fast response and accurate positioning under external magnetic field 254, 255 . Secondly, MNPs stability could be improved, because it directly affects its appli ion, for example, storage stability could be improved so that MNPs can be shipped and stored at room temperature .... ...
LiChrospher® HPLC Columns: LiChrospher® is a reliable and versatile traditionally produced spherical silica carrier with a particle size of 5µm or 10 µm, providing well balanced pressure / separation performance ratio. A broad range of modifications on LiChrospher® are very widely used by HPLC-users all over the world for a broad range of applications. LiChrospher® sorbents are available as reversed phase derivatives (RP-8, RP-18 endcapped, RP-18, RP-18 endcapped and RP-select B), medium polar (NH2, CN, DIOL) and polar derivatives (Si 60). Furthermore LiChrospher® PAH is highly efficient and selective for the separation of PAH; LiChrospher® WP is very well suited for the separation of peptides and low molecular weight proteins. LiChrospher® sorbents are available as Hibar® RT columns or as LiChroCART® cartridges in different lengths ans internal diameters. To operate with LiChroCART® cartridges, the cartridge holder manu-CART® has to be used.
"Analysis of thiols by microchip capillary electrophoresis for in situ planetary investigations". Microchip Capillary ... From an extraterrestrial sample, the organic content can be assessed using microchip capillary electrophoresis and selective ... "Enhanced amine and amino acid analysis using Pacific Blue and the Mars Organic Analyzer microchip capillary electrophoresis ... "Analysis of carbonaceous biomarkers with the Mars Organic Analyzer microchip capillary electrophoresis system: aldehydes and ...
Apollo 100 Sinville, Rondedrick; Soper, Steven A (2007). "High resolution DNA separations using microchip electrophoresis". ... "DNA sequencing and genotyping in miniaturized electrophoresis systems". Electrophoresis. 25 (21-22): 3564-3588. doi:10.1002/ ... Capillary electrophoresis Extension fragments are injected into the CE chamber where they are electrophoresed through a 125-167 ... The manufacturer claims that samples are ready for capillary electrophoresis within three hours of the sample and reagents ...
"Microchip immunoaffinity electrophoresis of antibody-thymidine kinase 1 complex". Electrophoresis. 36 (5): 813-7. doi:10.1002/ ... A microchip electrophoresis immunoaffinity assay for determination of serum thymidine kinase concentration has been described. ...
"Microchip immunoaffinity electrophoresis of antibody-thymidine kinase 1 complex". Electrophoresis. 36 (5): 813-7. doi:10.1002/ ...
Capillary electrophoresis (CE) and microcapillary gel electrophoresis (μCGE) are well-recognized microchip electrophoresis (MCE ... Jacobson SC, Koutny LB, Hergenroeder R, Moore AW, Ramsey JM (October 1994). "Microchip Capillary Electrophoresis with an ... These MCE and other electrophoresis based methods began to develop once capillary electrophoresis gained popularity in the ... Microchip electrophoresis can be applied generally as a method for high-throughput screening processes that help discover and ...
Toward a microchip-based solid-phase extraction method for isolation of nucleic acids. Electrophoresis, 23, 727-733 (2002).. ... Silica resins avoid these issues through integration on microchips, where solid phase extraction provides accurate analysis of ... cannot be integrated onto microchips because they require multiple hands-on processing steps. In addition, they also require ... usually conducted on a microchip coated in silica channels. Conventional methods for DNA extraction, such as ethanol ...
HPC is used as a sieving matrix for DNA separations by capillary and microchip electrophoresis. HPC is the main ingredient in ... Artificial Neural Network Optimization for Microchip Analysis". Analytical Chemistry. 75 (4): 986-994. doi:10.1021/ac020425z. ...
"Analysis of neuroactive amines in fermented beverages using a portable microchip capillary electrophoresis system" (PDF). ...
Composite Electrode Fabricated by In Situ Polymerization for Microchip Capillary Electrophoresis". Chemistry - A European ...
Maria Fernanda Mora, for excellence in the development and validation of chemical analysis methodology and electrophoresis ... From Spaceships to Microchips. Springer. p. 236. ISBN 978-3-319-54215-7. Retrieved 23 October 2018. National Academy of ...
Single-nucleotide mutations in a fragment can be more easily detected with MS than by gel electrophoresis alone. MALDI-TOF MS ... instances researchers have shown that they can increase the throughput of conventional sequencing through the use of microchips ... Quail MA, Gu Y, Swerdlow H, Mayho M (2012). "Evaluation and optimisation of preparative semi-automated electrophoresis systems ... Over that period, great advances were made in the technique, such as fluorescent labelling, capillary electrophoresis, and ...
... electrophoresis, microchip MeSH E05.196.401.200 - electrophoresis, cellulose acetate MeSH E05.196.401.220 - electrophoresis, ... electrophoresis, disc MeSH E05.196.401.402.250 - electrophoresis, gel, two-dimensional MeSH E05.196.401.485 - electrophoresis, ... electrophoresis, microchip MeSH E05.588.570.660 - oligonucleotide array sequence analysis MeSH E05.588.570.700 - protein array ... electrophoresis, microchip MeSH E05.196.630.570 - microarray analysis MeSH E05.196.630.570.660 - oligonucleotide array sequence ...
... forming process is used to fabricate film microchips for capillary electrophoresis (CE) [3-5] and for three-dimensional cell ... flexible film microchips such as μTAS (Micro Total Analysis Systems) and LOC (Lab-on-a-chip) devices, possibly in continuous ... Schaller T and Schomburg WK 2001 Low-cost production of single-use polymer capillary electrophoresis structures by ...
Microchip based electrophoresis is a promising alternative to capillary electrophoresis since it has the potential to provide ... Isoelectric focusing is the first step in two-dimensional gel electrophoresis, in which proteins are first separated by their ... It is a type of zone electrophoresis usually performed on proteins in a gel that takes advantage of the fact that overall ... of interest by first subjecting a solution of small molecules such as polyampholytes with varying pI values to electrophoresis ...
Chung, S.; Park, S. J.; Kim, J. K.; Chung, C.; Han, D. C.; Chang, J. K. (2003-10-01). "Plastic microchip flow cytometer based ... Electrophoresis. Wiley. 26 (19): 3716-3724. doi:10.1002/elps.200500173. ISSN 0173-0835. Takeuchi, S.; Garstecki, P.; Weibel, D ...
"DNA migration mechanism analyses for applications in capillary and microchip electrophoresis". Electrophoresis. 30 (12): 2014- ... Electrophoresis techniques used in the assessment of DNA damage include alkaline gel electrophoresis and pulsed field gel ... Separation of very large DNA fragments requires pulse field gel electrophoresis (PFGE). In field inversion gel electrophoresis ... Nucleic acid electrophoresis is an analytical technique used to separate DNA or RNA fragments by size and reactivity. Nucleic ...
Tellez Gabriel , EJCB, 2017, "Analysis of gap junctional intercellular communications using a dielectrophoresis-based microchip ... "Electrophoresis. 38 (11): 1466-1474. doi:10.1002/elps.201700020. ISSN 1522-2683. PMC 5547746. PMID 28256738.. ...
Besides, gel electrophoresis also was used to identify and differentiate the EBN base on their geographical origins. This is ... The Malaysian government has since employed RFID technology to thwart counterfeiting by micro-chipping nests with details about ... In this study, gel electrophoresis and liquid chromatographic were used for protein profiling and amino acids studies of cave ... Some other methods including DNA- based polymerase chain reactions, protein-based two-dimension gel electrophoresis and genetic ...
The microchip costs $25, whereas the robotic dispensers currently in use cost around $10,000.[citation needed] In March 2011, a ... Protein electrophoresis (general technique-not a specific test) Western blot (general technique-not a specific test) Liver ... "Microchip offers faster and cheaper way to test blood". CTV News. Bell Media. 2 February 2011. Retrieved 2 October 2016. Taylor ... In February 2011, Canadian researchers at the University of Calgary's Schulich School of Engineering announced a microchip for ...
Capillary and Pressure Driven Microchip for Blood Separation and Assay. Biomedical and Chemical Micro Sensors and Systems. ... electrophoresis, microchannel bends, and ultrasound standing waves.[citation needed] Therapeutic erythrocytapheresis is ...
By creating their own local fields, these motors are said to move through self-electrophoresis. Joseph Wang in 2008 was able to ... ranging from cell sorting microchip devices to directed drug delivery. Recently, there has been more research into developing ...
Second, each specimen receives an implanted microchip, called a passive integrated transponder, which identifies individual ... Electrophoresis. 23 (7-8): 1025-1032. doi:10.1002/1522-2683(200204)23:7/8. 3.0.CO;2-Y. PMID 11981849. Hua Yue, Gen; Li, Yang; ...
The four main areas of active research in the Ramsey group include: Microchip electrospray Microfluidic point of care ... and the Frederick Conference Capillary Electrophoresis Award (2000). Dr. Ramsey currently holds professional memberships with ... His current research with the university focuses on microscale and nanoscale devices such as microchip electrospray, microscale ...
doi:10.1016/s0168-583x(03)01025-5. Wang, Zhongke (October 2008). "Fabrication of integrated microchip for optical sensing by ... chip electrophoresis) Semiconductor (such FED spacer, packaging elements or interposer for IC components, CMOS or memory ...
In electrophoresis, a charged species in a liquid moves under the influence of an applied electric field. Electrophoresis has ... a PDMS microfluidic device implanted under the conjunctiva for drug delivery to the eye to treat ocular diseases and microchips ... Capillary electrophoresis thus became a focus for chemical and DNA separation. Thirdly, DARPA of the US Department of Defense ... In capillary electrophoresis, a long thin tube separates analytes by voltage as they migrate by electro-osmotic flow. For ...
UT Dallas' ceremonial mace contains a university seal surrounding a wafer embedded with Texas Instruments microchips, ... and human DNA when it is separated in a process called gel electrophoresis. Renovation and expansion of the Founders Building, ...
"Microchip offers faster and cheaper way to test blood". CTV News. Bell Media. 2 February 2011. Retrieved 2 October 2016.. ... Protein electrophoresis (general technique-not a specific test). *Western blot (general technique-not a specific test) ... In February 2011, Canadian researchers at the University of Calgary's Schulich School of Engineering announced a microchip for ... The microchip costs $25, whereas the robotic dispensers currently in use cost around $10,000.[citation needed] ...
Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application ... the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip ... Optical Detection Systems for Microchips, J.M. Karlinsey and J.P. Landers Microfabricated Electrophoresis Devices for High- ... Materials and Modification Strategies for Electrophoresis Microchips, C. S. Henry and B.M. Dressen Microfluidic Devices with ...
Recent advances in miniaturization-The role of microchip electrophoresis in clinical analysis. ELECTROPHORESIS, 35: 138-146. ... Recent advances in miniaturization-The role of microchip electrophoresis in clinical analysis. ...
Microchip capillary electrophoresis (CE) was one of the first techniques demonstrating the advantages of scaling down ... Microchip capillary electrophoresis (CE) was one of the first techniques to demonstrate the advantages of scaling down ... and Use for DNA Separations by Microchip Electrophoresis", J Colloid Interface Sci. 2011, 357, 345-353 ... "Ultrafast DNA sequencing on a microchip by a hybrid separation mechanism that gives 600 bases in 6.5 minutes", PNAS 2008, 105, ...
small business, SBIR, microchip, capillary electrophoresis, CE, inorganic aerosol, continuous monitoring, PM2.5, ions, cations ... Microchip Capillary Electrophoresis for Online Measurement of Inorganic Aerosols. EPA Contract Number: EPD04012. Title: ... Microchip Capillary Electrophoresis for Online Measurement of Inorganic Aerosols. Investigators: Hering, Susanne Small Business ... microchip capillary electrophoresis, human exposure, atmospheric aerosols, particulate matter mass, PM2.5, continuous emissions ...
Microchip Non-Aqueous Capillary Electrophoresis (μNACE) Method to Analyze Long-Chain Primary Amines. ...
... hybrid device was developed to enable the integration of cell culture with analysis by microchip electrophoresis and ... Integrated hybrid polystyrene-polydimethylsiloxane device for monitoring cellular release with microchip electrophoresis and ... Integrated hybrid polystyrene-polydimethylsiloxane device for monitoring cellular release with microchip electrophoresis and ... microchip electrophoresis, and electrochemical detection to monitor neurotransmitter release from PC 12 cells. ...
We report on label-free monitoring of microfluidic free-flow electrophoresis (μFFE) separations in real-time using a custom ... Label-free real-time imaging in microchip free-flow electrophoresis. applying high speed deep UV fluorescence scanning S. ... Label-free real-time imaging in microchip free-flow electrophoresis applying high speed deep UV fluorescence scanning† ... free-flow electrophoresis. (μFFE) separations in real-time using a custom built high speed deep UV laser scanner. In ...
A simple, rapid and efficient method based on microchip electrophoresis coupled with fluorescence detection (MCE-FLD) was ... glutathione and cysteine in macrophage RAW264.7 cells by microchip electrophoresis with fluorescence detection.. [Feng-Qin Tu, ... The rapid separation and sensitive detection of the derivatives were achieved on a glass microchip within 70s in a running ...
Capillary electrophoresis of intact unfractionated heparin and related impurities. *Microchip capillary electrophoresis for in ... Capillary electrophoresis and microchip capillary electrophoresis are powerful analytical tools that are particularly suited ... Capillary Electrophoresis and Microchip Capillary Electrophoresis: Principles, Applications, and Limitations. Skip to ... Capillary electrophoresis with electrochemical detection. *Overcoming challenges in using microchip electrophoresis for ...
Evolution Cluster Faculty Search Seminar: Analysis of Organic Biomarkers Using Integrated Microchip Capillary Electrophoresis ... Microcapillary electrophoresis (CE) coupled with laser-induced fluorescence (LIF) detection enables rapid, automated, and ...
Results of sizing from the microchip electrophoresis were compared with those obtained in the capillary electrophoresis for ... reaction and capillary electrophoresis laser induced fluorescence using microchip technology. Electrophoresis. 2004; 25: 3860- ... The aim of this work was to evaluate two paternity cases by microchip electrophoresis and the validation of the methodology by ... The aim of this work was to evaluate two paternity cases by microchip electrophoresis and the validation of the methodology by ...
... ... In this work, a separation based microdialysis-microchip electrophoresis system with fluorescence detection was developed for ... The derivatized sample was then injected, separated and detected by microchip electrophoresis with fluorescence detection. This ... CE separation of amino acids served as the basis for optimization of the amino acid separation in the microchip electrophoresis ...
Near real-time monitoring of carbohydrates during beer processing by a microchip capillary electrophoresis technology ... Near real-time monitoring of carbohydrates during beer processing by a microchip capillary electrophoresis technology ... On-line instruments automatically sip, filter, and deliver samples to our microchip for analysis. The instrument design calls ... hold the only demonstrated technology for combining capillary electrophoresis and pulsed amperometric detection on a microchip ...
electrophoresis microchip; contactless conductivity detection; biopharma raw materials; vitamins; metal cations;. Subjects:. ... Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection. Vázquez, Mercedes ... We demonstrate the application of electrophoresis microchips with capacitively-coupled contactless conductivity detection (C4D ... Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection. In: μTAS 2009 - 13th ...
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One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to ... Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016- ... Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016- ... Attention is also given to online or in-line extraction methods that have been used for electrophoresis. ...
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Microchips and Slabs offers chapters covering: Solvents and Buffer Solutions; Fundamentals of Electrophoresis; Open Layout; and ... The first book to offer a detailed account of Toroidal Electrophoresis-written by one of its creators Compares the toroidal ... Featuring numerous illustrations throughout, Open and Toroidal Electrophoresis: Ultra-High Separation Efficiencies in ... The book finishes with an examination of the applications of Toroidal Electrophoresis. ...
Capillary electrophoresis and microchip capillary electrophoresis are powerful analytical tools that are particularly suited ... b>Explores the benefits and limitations of the latest capillary electrophoresis techniques

... Capillary Electrophoresis and Microchip Capillary Electrophoresis. Principles, Applications, and Limitations. Carlos D. García ... Capillary electrophoresis and microchip capillary electrophoresis are powerful analytical tools that are particularly suited ...
... Charles S. Henry, Min Zhong, Susan M. Lunte, Moon Kim, Haim ...
Three-Electrode Electrochemical Detector and Platinum Film Decoupler Integrated with a Capillary Electrophoresis Microchip for ...
Microchip Capillary Zone Electrophoresis (Microchip CZE). Microchip capillary zone electrophoresis (microchip CZE) separates ... 3. Applications of Microchip Electrophoresis. Microchip electrophoresis (MCE) has been a key technology to study proteomics, ... Microchip electrophoresis (MCE) is a miniaturized form of capillary electrophoresis. Electrophoresis is a common technique to ... Electrophoresis 1997, 18, 2134-2144.. *Castro, E.R.; Manz, A. Present state of microchip electrophoresis: State of the art and ...
Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006- ... Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006- ... Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006- ... Poor sensitivity is still considered to be one of the major limitations of electrophoresis, which is surprising given the power ...
... be out our glad Microchip Capillary Electrophoresis: people that will submit you keep in Working your net information. Free ... Your Microchip Capillary Electrophoresis: Methods and is collected a current or great Abolition. This download risk to the is ... Your Microchip Capillary Electrophoresis: Methods and did a version that this hijinks could nearly get. Your website sent a ... 20th Microchip Capillary Electrophoresis: browser: Privacy machine below 50 travel of 6:41Hello same beta History fish. Market ...
Gold nanoparticle-enhanced microchip capillary electrophoresis. / Pumera, M.; Wang, J.; Grushka, E.; Polsky, R. ... Pumera M, Wang J, Grushka E, Polsky R. Gold nanoparticle-enhanced microchip capillary electrophoresis. Analytical Chemistry. ... Pumera, M. ; Wang, J. ; Grushka, E. ; Polsky, R. / Gold nanoparticle-enhanced microchip capillary electrophoresis. In: ... Pumera, M, Wang, J, Grushka, E & Polsky, R 2001, Gold nanoparticle-enhanced microchip capillary electrophoresis, Analytical ...
1. A microchip capillary electrophoresis (CE) system comprising: A separation channel and CE electrodes continuously applying ... Microchip capillary electrophoresis (CE) utilizing a sample injector based on a mechanical valve rather than electrokinetic ... 6. A method for analyzing a sample by microchip capillary electrophoresis, the method characterized by the steps of: Applying a ... Patent application title: Microchip Capillary Electrophoresis Absent Electrokinetic Injection. Inventors: Xuefei Sun (Richland ...
Capillary electrophoresis,br/,Conductivity detection,br/,Hybrid detection electrodes,br/,Microchip,br/,Miniaturization,br/,Wall ... Wall-jet conductivity detector for microchip capillary electrophoresis ... br/,Microfluidic devices,br/,Electrochemical detection,br/,Conductometric detector,br/,Zone-electrophoresis,br/,Contactless,br ... Wang, J., Chen, G., & Muck, A. (2009). Wall-jet conductivity detector for microchip capillary electrophoresis. Talanta, 78(1), ...
Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques: Medicine & Health Science Books @ Amazon . ... HANDBOOK OF CAPILLARY AND MICROCHIP ELECTROPHORESIS AND ASSOCIATED MICROTECHNIQUES PDF - ... Although capillary electrophoresis (CE) technology has evolved the use of microchip electrophoresis and associated ... the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip ...
Performance of Microchip-based Electrophoresis. Separation Rate. Microchip electrophoresis separation times are much shorter ... Yet the benefits of microchip-based electrophoresis cannot be ignored. Microchip electrophoresis shows great potential over ... Microchip electrophoresis succeeded in detecting the mutations, but at a decreased resolution. Conversely, microchip-based HDA ... The material composition of the microchip can have a large influence on the effectiveness of microchip electrophoresis. ...
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  • In this work, a polystyrene (PS)-polydimethylsiloxane (PDMS) hybrid device was developed to enable the integration of cell culture with analysis by microchip electrophoresis and electrochemical detection. (rsc.org)
  • This PS-PDMS hybrid device integrates multiple processes including continuous sampling from a cell culture dish, on-chip pump and valving technologies, microchip electrophoresis, and electrochemical detection to monitor neurotransmitter release from PC 12 cells. (rsc.org)
  • Dual labeling for simultaneous determination of nitric oxide, glutathione and cysteine in macrophage RAW264.7 cells by microchip electrophoresis with fluorescence detection. (sigmaaldrich.com)
  • A simple, rapid and efficient method based on microchip electrophoresis coupled with fluorescence detection (MCE-FLD) was developed for simultaneous determination of nitric oxide (NO), glutathione (GSH) and cysteine (Cys) using dual labeling strategy. (sigmaaldrich.com)
  • The rapid separation and sensitive detection of the derivatives were achieved on a glass microchip within 70s in a running buffer of 20mM H3Cit-Na2HPO4 solution (pH 7.4) containing 15% (v/v) acetonitrile at a separation voltage of 2400V. (sigmaaldrich.com)
  • Microcapillary electrophoresis (CE) coupled with laser-induced fluorescence (LIF) detection enables rapid, automated, and extremely sensitive analyses of organic biomarkers (down to 70 pM or sub pptr). (upenn.edu)
  • In this work, a separation based microdialysis-microchip electrophoresis system with fluorescence detection was developed for the determination of amino acid neurotransmitters from microdialysis samples collected from rat brain striatum. (ku.edu)
  • Initial experiments employed capillary electrophoresis with laser induced fluorescence (CE-LIF) detection to evaluate the optimum buffer conditions for the separation of amino acid standards. (ku.edu)
  • The derivatized sample was then injected, separated and detected by microchip electrophoresis with fluorescence detection. (ku.edu)
  • Because we hold the only demonstrated technology for combining capillary electrophoresis and pulsed amperometric detection on a microchip format, we can uniquely offer fast, simple, and reliable sugar analysis. (mbaa.com)
  • We demonstrate the application of electrophoresis microchips with capacitively-coupled contactless conductivity detection (C4D) to the analysis of wa-ter-soluble vitamins and metal cations in raw material solutions that are subse-quently fed into bioreactors for the production of biologics. (dcu.ie)
  • Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with tumor-related inflammation. (nature.com)
  • Capillary and microchip electrophoresis (CE and ME) are two promising electrophoretic methods for amyloid oligomer and aggregate detection. (uark.edu)
  • Many of these developments have focused on the coupling of capillary electrophoresis (CE), a separation technique with low sample consumption and high resolving power, and mass spectrometry (MS), a sensitive detection method for interrogating all ions in a sample in a single analysis. (mdpi.com)
  • A sensitive assay based on specific aptamer binding for the detection of Salmonella enterica serovar Typhimurium in milk samples by microchip capil. (nih.gov)
  • To develop a simple and quick assay for the detection of S. aureus at low concentrations, we propose to use the Cy5-Van for labeling the S. aureus coupled with an on-line multiple-concentration in microchip electrophoresis. (rhhz.net)
  • End-Column Detection for Capillary Zone Electrophoresis," Anal. (freepatentsonline.com)
  • Axial-beam absorbance detection for capillary electrophoresis," Journal of Chromatography, 550(1991) pp. 831-837. (freepatentsonline.com)
  • The diluted samples are sequentially introduced through microcha n-nels by electro-osmotic force, and their laser-induced fluorescence signals measured by capillary electrophoresis. (elsevier.com)
  • Here we reported a simple and sensitive strategy to test S. Typhimurium by microchip capillary electrophoresis couple with laser-induced fluorescence (MCE-LIF) based on the specific reaction between the bacterium and corresponding aptamers. (nih.gov)
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  • The objective of this research was to manufacture a miniaturised microchip capillary electrophoresis (MCE) system, which can be used to analyse suspected chemical agents accurately and rapidly. (ucc.ie)
  • The optimal separation conditions consisted of 200 mM borate, 80 mM SDS, 5% acetonitrile using a 21 cm long serpentine channel in a PDMS microchip. (ku.edu)
  • In Chapter 3, a low-cost customised MCE system with polydimethylsiloxane (PDMS) microchip and printed circuit board (PCB) C4D electrodes cell was fabricated and tested. (ucc.ie)
  • A new poly(dimethylsiloxane) (PDMS)-based microchip capillary electrophoresis (CE) device, with a thick-film electrochemical detector, is described. (nanorobots.cz)
  • The end-column design relies on screen-printing the amperometric carbon working electrode on the base plate of a PDMS microchip (opposite to the exit of the microchannel). (nanorobots.cz)
  • Unlike traditional electrophoresis techniques such as heteroduplex analysis (HDA) and single-strand conformation polymorphism (SSCP), which typically utilize slab gels (S. Liu et al. (ucdavis.edu)
  • The system provides clear advantages over traditional electrophoresis for DNA quantitation (viral load, gene expression), mutation analysis, and size polymorphisms analysis (VNTR, STR, m. (selectscience.net)
  • The new technique is a 2D version of traditional electrophoresis, involving pulses of an electric field situated perpendicular to the main one. (medgadget.com)
  • abstract = "We describe here the use of gold nanoparticles in conjunction with chip-based capillary electrophoresis to improve the selectivities between solutes and to increase the efficiency of the separation. (elsevier.com)
  • abstract = "A high-performance monitoring system for human blood glucose levels was developed using microchip electrophoresis with a plastic chip. (elsevier.com)
  • abstract = "To realise portable microchip capillary electrophoresis systems for routine use in point-of- care (POC) settings, measurements must be robust across many single-use chips. (utwente.nl)
  • Microchip capillary electrophoresis (CE) was one of the first techniques to demonstrate the advantages of scaling down conventional instrumental techniques to a microfluidic format. (micronit.com)
  • We report on label-free monitoring of microfluidic free-flow electrophoresis (μFFE) separations in real-time using a custom built high speed deep UV laser scanner. (rsc.org)
  • Therefore, we developed a polymer based microfluidic device from polydimethylsiloxane, which integrates serial dilution and capillary electrophoresis functions in a single device. (elsevier.com)
  • Leading chemists and engineers concisely explain the principles behind microchip capillary electrophoresis and demonstrate its use in a variety of biochemical applications, ranging from the analysis of DNA, proteins, and peptides to single cell analysis and measuring the impact of surface modification on flow in microfluidic channels. (blogspot.com)
  • After the adsorption of 1st anti-PICP antibody on the surface of microchannel (300 μm width, 100 μm depth) on cyclic olefin copolymers (COC) microchip, sample and peroxidase-conjugated 2nd anti-PICP antibody mixture was introduced into a microchannel for 30 min, followed by washing and peroxidase activity was measured for the determination of PICP level. (nii.ac.jp)
  • We demonstrated the possible application of microchip for determination of PICP levels with high sensitivity and accuracy, and the potential for the dental clinical diagnosis. (nii.ac.jp)
  • Electrophoresis is a common technique to separate macromolecules such as nucleic acids (DNA, RNA) and proteins. (encyclopedia.pub)
  • Chapter 6 Capillary Electrophoresis of Nucleic Acids. (biz-sugimoto.info)
  • The Fragment Analyzer™ Automated CE System is a fluorescence-based capillary electrophoresis instrument for the accurate sizing, quantification, and qualification of nucleic acids (DNA and RNA). (selectscience.net)
  • A new end-column 'hybrid' contactless conductivity detector for microchip capillary electrophoresis (CE) was developed. (mpg.de)
  • A new method for mass fabrication of silver ink conductivity detector electrodes for poly(methylmethacrylate) (PMMA) microchip electrophoretic systems has been developed based on screen-printing technology. (mpg.de)
  • We attributed this to a significant variation in microchannel surface properties, while microchip dimension and detector variations were small in comparison. (utwente.nl)
  • books psych more members in the Microchip Capillary Electrophoresis: Methods and Protocols 2006 Buddhism. (planetdis.com)
  • Microchip Capillary Electrophoresis: Methods and Protocols provides a practical starting point for either initiating research in the field of microchip capillary electrophoresis or understanding the full range of what can be done with existing systems. (blogspot.com)
  • Amplified STR fragments can be separated and detected by the slab gel electrophoresis. (scielo.br)
  • Presents the theory and applications of Toroidal Capillary, Microchip, and Slab Electrophoresis to analytical chemists across a range of disciplines Written by one of the developers of Toroidal Capillary Electrophoresis (TCE), this book is the first to present this novel analytical technique, in detail, to the field of analytical chemistry. (magrudy.com)
  • Since its discovery in the 1930s by Arne [ 1 ] , traditional slab gel electrophoresis (SGE) has been widely used until today. (encyclopedia.pub)
  • 2000) compared microchip electrophoresis to conventional slab gel separations in detecting mutations in clinical samples. (ucdavis.edu)
  • Results showed that microchip electrophoresis was fifty times faster than slab gel methods while maintaining a comparable accuracy level (± 5 base pairs). (ucdavis.edu)
  • This report also assesses the growth and market potential for agarose and polyacrylamide gel electrophoresis techniques. (prnewswire.com)
  • 2000), microchip electrophoresis employs microfabricated wafers as a separation medium for molecular samples. (ucdavis.edu)
  • 2000). Recent strides in separation technology like capillary electrophoresis (CE) focus on reducing costs by miniaturizing the procedure. (ucdavis.edu)
  • 2000). Using short separation channels and narrow sample bands, microchip electrophoresis can sequence samples more quickly than traditional techniques (S. Liu et al. (ucdavis.edu)
  • 2000). Although microchip electrophoresis possesses these advantages, its purported improvements in precision have not been proven (Schmalzing et al. (ucdavis.edu)
  • 2000). This is four times faster than conventional SSCP and 100 times faster than traditional gel electrophoresis. (ucdavis.edu)
  • Analysis of Sample Injection and Brand-Broadening in Capillary Electrophoresis Microchips," Techinal Proceedings of the MSM 2000, San Diego, CA, March 27-29, 2000. (freepatentsonline.com)
  • Systems that couple microdialysis with capillary electrophoresis (CE) based separations have gained popularity due to their ability to perform online analysis with high temporal resolution. (ku.edu)
  • Our work established an online microdialysis microchip setup that can be further modified to perform high temporal resolution studies for studying dynamic changes of neuroactive analytes in the brain following stroke. (ku.edu)
  • Chapter 48 Microdialysis and Microchip Systems. (biz-sugimoto.info)
  • Microdialysis sampling combined with microchip electrophoresis yields a separation-based sensor that can be used to continuously monitor neurotransmitters and nitric oxide metabolites in awake freely roaming animals. (selectbiosciences.com)
  • Non-Ionic, Thermo-Responsive DEA/DMA Nanogels: Synthesis, Characterization, and Use for DNA Separations by Microchip Electrophoresis", J Colloid Interface Sci. (micronit.com)
  • recent advances have allowed the CE to be performed using the microchip devices (Panaro et al. (scielo.br)
  • Facing the review paper assignment in scientific writing (English 104E), Claude Nguyen chose to discuss a fascinating group of studies that report advances in microchip electrophoresis, an emerging field that blends molecular biology and computer engineering. (ucdavis.edu)
  • Although electrophoresis is a standardized technique, there have been considerable technology advances because of its ever-expanding research applications. (prnewswire.com)
  • The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i. (intechopen.com)
  • We developed a microchip electrophoresis (MCE) method for rapid separation of phosphopeptides with on-chip electrospray ionization (ESI) facilitating online sample introduction to the mass spectrometer (MS). With the method, two monophosphorylated positional isomers of insulin receptor peptide (IR1A and IR1B) and a triply phosphorylated insulin receptor peptide (IR3), all with the same amino acid sequence, were separated from the nonphosphorylated peptide (IR0) in less than one minute. (aalto.fi)
  • As a few additional functions such as sample preparation, washing, and incubation with antibodies and derivatization with dyes can be integrated on a single stamp size microchip, MCE has the potential to be adapted for portable POC and clinical diagnostics devices. (encyclopedia.pub)
  • This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of online/in-line concentration methods in capillaries and microchips, covering the period July 2016-June 2018. (edu.au)
  • A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. (google.ca)
  • To develop the analysis system of biomarkers in periodontal disease in dental clinic, we first developed the quantitative analysis system based on the antigen-antibody reaction in microchannel on microchip. (nii.ac.jp)
  • Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. (routledge.com)
  • Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques: Medicine & Health Science Books @ Amazon .com. (biz-sugimoto.info)
  • Although capillary electrophoresis (CE) technology has evolved the use of microchip electrophoresis and associated microtechniques, with a. (biz-sugimoto.info)
  • Emphasizing microseparations and microfluidics, this book includes chapters describing the microchop of microchip electrophoresis and associated microtechniques. (biz-sugimoto.info)
  • The aim of this work was to evaluate two paternity cases by microchip electrophoresis and the validation of the methodology by comparison of the results with those obtained in a commercial genetic analyzer. (scielo.br)
  • The automated microchip electrophoresis analyzer could someday detect organic biosignatures in extraterrestrial soil. (mbtmag.com)
  • The CE separation of amino acids served as the basis for optimization of the amino acid separation in the microchip electrophoresis experiments. (ku.edu)
  • In this paper, an optimal microelectrode model was obtained via the improved evolutionary structural optimization (ESO) method, the effect of topological parameters on the sterilization efficiency was clarified, and the optimized microchip was applied to the sterilization of blueberry juice to verify its feasibility. (springer.com)
  • This report will 'determine the current status of the electrophoresis industry and assess its growth potential through 2018. (prnewswire.com)
  • Microchip has been widely used in the biochemical field, but it is rarely applied in the food area. (springer.com)
  • In comparison with traditional analytical techniques, capillary electrophoresis and microchip capillary electrophoresis offer the benefits of speed, small sample and solvent consumption, low cost, and the possibility of miniaturization. (separationsnow.com)
  • With contributions from a staff of major analytical scientists, Capillary Electrophoresis and Microchip Capillary Electrophoresis explains how researchers can take complete good thing about the entire most modern innovations, emphasizing functions within which capillary electrophoresis has confirmed superiority over different analytical techniques. (wswcgroup.com)
  • The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques. (intechopen.com)
  • MCE offers many advantages over conventional capillary electrophoresis techniques such as the integration of different separation functions onto the chip, the consumption of small amounts of sample and reagents, faster analyses and efficient separations [ 6 ] [ 7 ] . (encyclopedia.pub)
  • compared to conventional analytical recommendations, capillary electrophoresis and microchip capillary electrophoresis supply the advantages of velocity, small pattern and solvent intake, cost-efficient, and the potential for miniaturization. (wswcgroup.com)
  • The significance of this technology is clear, since long operating times and expensive biological samples are key factors limiting the science that can be performed with conventional electrophoresis. (ucdavis.edu)
  • This article overviews the microchip and conventional capillary electrophoretic techniques for analysis of a wide variety of explosive compounds and mixtures. (elsevier.com)
  • Pumera, M 2006, ' Analysis of explosives via microchip electrophoresis and conventional capillary electrophoresis: A review ', Electrophoresis , vol. 27, no. 1, pp. 244-256. (elsevier.com)
  • Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. (wiley.com)
  • However, capillary electrophoresis (CE) has become increasingly popular for the STR typing and is the method of choice for the analysis of PCR products generated in genotyping tests. (scielo.br)
  • While the gel method took 64 minutes to resolve a mutation, the same mutation was detected on microchip in only 68.4 seconds. (ucdavis.edu)
  • A novel method for fast profiling of complex oligosaccharides released from glycoproteins based on microchip electrophoresis (μ-CE) is presented here. (elsevier.com)
  • While further investigation is necessary, the novel method proposed in this thesis gave promising results and is attractive for use in POC settings due to its simplicity: no additional sample manipulation, microchip changes, or system expansions are required for implementation. (utwente.nl)
  • Electrophoresis has been the method of choice for several decades to physically separate macromolecules such as nucleic acid fragments, RNA and proteins according to their charge and molecular size. (prnewswire.com)
  • The role of electrophoresis as an analytical separation method for both nucleic acid and protein molecules was examined. (prnewswire.com)
  • The invention relates to a method for separating a target for measurement utilizing electrophoresis, particularly capillary electrophoresis efficiently in high sensitivity and in a short period of time. (google.co.uk)
  • Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. (freepatentsonline.com)
  • The analysis of finite element method (FEM) results showed that planar comb teeth (PCT) form, quadrilateral electrode structure with 100-μm electrode spacing, was the ideal model for the microchip. (springer.com)
  • More particularly, this invention relates to a multi-channel capillary electrophoresis device and method wherein the distortion of a sample zone exiting from the end of a channel is controlled thereby resulting in enhanced detectability of such sample zone. (google.com)
  • Electrophoresis is an analytical technique that has been applied to resolve complex mixtures containing DNA, proteins, and other chemical or biological species. (encyclopedia.pub)
  • The microchip system has an extremely tiny sieve structure built into it that can sort through continuous streams of biological fluids and separate proteins accurately by size. (medgadget.com)
  • Under optimal conditions, high-performance separation of the N-linked complex oligosaccharides released from ribonuclease B, fetuin, α 1 -acid glycoprotein (AGP) and IgG was achieved using polymethylmethacrylate (PMMA) microchips with an effective separation channel of 30 mm. (elsevier.com)
  • The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. (intechopen.com)