Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
Electrodes which can be used to measure the concentration of particular ions in cells, tissues, or solutions.
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.
Electrodes with an extremely small tip, used in a voltage clamp or other apparatus to stimulate or record bioelectric potentials of single cells intracellularly or extracellularly. (Dorland, 28th ed)
Solution titration in which the end point is read from the electrode-potential variations with the concentrations of potential determining ions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Fluorocarbon polymers are synthetic, high-molecular-weight compounds consisting of carbon chains with fluorine atoms replacing hydrogen atoms, known for their chemical and thermal stability, as well as their resistance to water, oil, and heat, which make them useful in various medical applications such as biocompatible coatings, drug delivery systems, and implant materials.
An allotropic form of carbon that is used in pencils, as a lubricant, and in matches and explosives. It is obtained by mining and its dust can cause lung irritation.
Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.
Methods of creating machines and devices.
Use of electric potential or currents to elicit biological responses.
A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
Electronic hearing devices typically used for patients with normal outer and middle ear function, but defective inner ear function. In the COCHLEA, the hair cells (HAIR CELLS, VESTIBULAR) may be absent or damaged but there are residual nerve fibers. The device electrically stimulates the COCHLEAR NERVE to create sound sensation.
Determination of the quantity of a material present in a mixture by measurement of its effect on the electrical conductivity of the mixture. (Webster, 3d ed)
Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.
The resistance to the flow of either alternating or direct electrical current.
Enzymes which are immobilized on or in a variety of water-soluble or water-insoluble matrices with little or no loss of their catalytic activity. Since they can be reused continuously, immobilized enzymes have found wide application in the industrial, medical and research fields.
A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
The physical effects involving the presence of electric charges at rest and in motion.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Electric power supply devices which convert biological energy, such as chemical energy of metabolism or mechanical energy of periodic movements, into electrical energy.
Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
Inorganic compounds that contain tin as an integral part of the molecule.
Inorganic compounds that contain silver as an integral part of the molecule.
The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
A technique of measuring the dielectric properties of materials, which vary over a range of frequencies depending on the physical properties of the material. The technique involves measuring, over a range of frequencies, ELECTRICAL IMPEDANCE and phase shift of an electric field as it passes through the material.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
Potential cavity which separates the ARACHNOID MATER from the DURA MATER.
Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.
Inorganic salts of the hypothetical acid ferrocyanic acid (H4Fe(CN)6).
An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.
Nanometer-sized tubes composed mainly of CARBON. Such nanotubes are used as probes for high-resolution structural and chemical imaging of biomolecules with ATOMIC FORCE MICROSCOPY.
An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)
The lower chamber of the COCHLEA, extending from the round window to the helicotrema (the opening at the apex that connects the PERILYMPH-filled spaces of scala tympani and SCALA VESTIBULI).
The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Medical devices which substitute for a nervous system function by electrically stimulating the nerves directly and monitoring the response to the electrical stimulation.
Destruction by passage of a galvanic electric current, as in disintegration of a chemical compound in solution.
Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.
Artificial device such as an externally-worn camera attached to a stimulator on the RETINA, OPTIC NERVE, or VISUAL CORTEX, intended to restore or amplify vision.
The perceived attribute of a sound which corresponds to the physical attribute of intensity.
The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
An electrochemical technique for measuring the current that flows in solution as a function of an applied voltage. The observed polarographic wave, resulting from the electrochemical response, depends on the way voltage is applied (linear sweep or differential pulse) and the type of electrode used. Usually a mercury drop electrode is used.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
The research and development of ELECTRICAL EQUIPMENT AND SUPPLIES for such medical applications as diagnosis, therapy, research, anesthesia control, cardiac control, and surgery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A general term for the complete loss of the ability to hear from both ears.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
Coating with a metal or alloy by electrolysis.
Elements of limited time intervals, contributing to particular results or situations.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Techniques used mostly during brain surgery which use a system of three-dimensional coordinates to locate the site to be operated on.
Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
The ability of a substrate to allow the passage of ELECTRONS.
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
A metallic element with the atomic symbol Ir, atomic number 77, and atomic weight 192.22.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.
Devices that control the supply of electric current for running electrical equipment.
A technique in which electric pulses of intensity in kilovolts per centimeter and of microsecond-to-millisecond duration cause a temporary loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Characteristics or attributes of the outer boundaries of objects, including molecules.
The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.
The scientific discipline concerned with the physiology of the nervous system.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Lens-shaped structure on the inner aspect of the INTERNAL CAPSULE. The SUBTHALAMIC NUCLEUS and pathways traversing this region are concerned with the integration of somatic motor function.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Nanometer-scale wires made of materials that conduct electricity. They can be coated with molecules such as antibodies that will bind to proteins and other substances.
Diamond. A crystalline form of carbon that occurs as hard, colorless or tinted isomeric crystals. It is used as a precious stone, for cutting glass, and as bearings for delicate mechanisms. (From Grant & Hackh's Chemical Dictionary, 5th ed)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.
Energy transmitted from the sun in the form of electromagnetic radiation.
Procedures for correcting HEARING DISORDERS.
The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).
A computer based method of simulating or analyzing the behavior of structures or components.
Electrical devices that are composed of semiconductor material, with at least three connections to an external electronic circuit. They are used to amplify electrical signals, detect signals, or as switches.
The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.
The audibility limit of discriminating sound intensity and pitch.
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Use of sound to elicit a response in the nervous system.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
The ability of a substrate to retain an electrical charge.
The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
The science pertaining to the interrelationship of psychologic phenomena and the individual's response to the physical properties of sound.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
A genus of gram-negative, anaerobic, metal-reducing bacteria in the family Geobacteraceae. They have the ability to oxidize a variety of organic compounds, including AROMATIC HYDROCARBONS.
Therapeutic introduction of ions of soluble salts into tissues by means of electric current. In medical literature it is commonly used to indicate the process of increasing the penetration of drugs into surface tissues by the application of electric current. It has nothing to do with ION EXCHANGE; AIR IONIZATION nor PHONOPHORESIS, none of which requires current.
Fields representing the joint interplay of electric and magnetic forces.
Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
The time from the onset of a stimulus until a response is observed.
The use of specifically placed small electrodes to deliver electrical impulses across the SKIN to relieve PAIN. It is used less frequently to produce ANESTHESIA.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.

Competitive mechanisms subserve attention in macaque areas V2 and V4. (1/2220)

It is well established that attention modulates visual processing in extrastriate cortex. However, the underlying neural mechanisms are unknown. A consistent observation is that attention has its greatest impact on neuronal responses when multiple stimuli appear together within a cell's receptive field. One way to explain this is to assume that multiple stimuli activate competing populations of neurons and that attention biases this competition in favor of the attended stimulus. In the absence of competing stimuli, there is no competition to be resolved. Accordingly, attention has a more limited effect on the neuronal response to a single stimulus. To test this interpretation, we measured the responses of neurons in macaque areas V2 and V4 using a behavioral paradigm that allowed us to isolate automatic sensory processing mechanisms from attentional effects. First, we measured each cell's response to a single stimulus presented alone inside the receptive field or paired with a second receptive field stimulus, while the monkey attended to a location outside the receptive field. Adding the second stimulus typically caused the neuron's response to move toward the response that was elicited by the second stimulus alone. Then, we directed the monkey's attention to one element of the pair. This drove the neuron's response toward the response elicited when the attended stimulus appeared alone. These findings are consistent with the idea that attention biases competitive interactions among neurons, causing them to respond primarily to the attended stimulus. A quantitative neural model of attention is proposed to account for these results.  (+info)

Neural encoding in orbitofrontal cortex and basolateral amygdala during olfactory discrimination learning. (2/2220)

Orbitofrontal cortex (OFC) is part of a network of structures involved in adaptive behavior and decision making. Interconnections between OFC and basolateral amygdala (ABL) may be critical for encoding the motivational significance of stimuli used to guide behavior. Indeed, much research indicates that neurons in OFC and ABL fire selectively to cues based on their associative significance. In the current study recordings were made in each region within a behavioral paradigm that allowed comparison of the development of associative encoding over the course of learning. In each recording session, rats were presented with novel odors that were informative about the outcome of making a response and had to learn to withhold a response after sampling an odor that signaled a negative outcome. In some cases, reversal training was performed in the same session as the initial learning. Ninety-six of the 328 neurons recorded in OFC and 60 of the 229 neurons recorded in ABL exhibited selective activity during evaluation of the odor cues after learning had occurred. A substantial proportion of those neurons in ABL developed selective activity very early in training, and many reversed selectivity rapidly after reversal. In contrast, those neurons in OFC rarely exhibited selective activity during odor evaluation before the rats reached the criterion for learning, and far fewer reversed selectivity after reversal. The findings support a model in which ABL encodes the motivational significance of cues and OFC uses this information in the selection and execution of an appropriate behavioral strategy.  (+info)

Physiological properties of raphe magnus neurons during sleep and waking. (3/2220)

Neurons in the medullary raphe magnus (RM) that are important in the descending modulation of nociceptive transmission are classified by their response to noxious tail heat as ON, OFF, or NEUTRAL cells. Experiments in anesthetized animals demonstrate that RM ON cells facilitate and OFF cells inhibit nociceptive transmission. Yet little is known of the physiology of these cells in the unanesthetized animal. The first aim of the present experiments was to determine whether cells with ON- and OFF-like responses to noxious heat exist in the unanesthetized rat. Second, to determine if RM cells have state-dependent discharge, the activity of RM neurons was recorded during waking and sleeping states. Noxious heat applied during waking and slow wave sleep excited one group of cells (ON-U) in unanesthetized rats. Other cells were inhibited by noxious heat (OFF-U) applied during waking and slow wave sleep states in unanesthetized rats. NEUTRAL-U cells did not respond to noxious thermal stimulation applied during either slow wave sleep or waking. ON-U and OFF-U cells were more likely to respond to noxious heat during slow wave sleep than during waking and were least likely to respond when the animal was eating or drinking. Although RM cells rarely respond to innocuous stimulation applied during anesthesia, ON-U and OFF-U cells were excited and inhibited, respectively, by innocuous somatosensory stimulation in the unanesthetized rat. The spontaneous activity of >90% of the RM neurons recorded in the unanesthetized rat was influenced by behavioral state. OFF-U cells discharged sporadically during waking but were continuously active during slow wave sleep. By contrast, ON-U and NEUTRAL-U cells discharged in bursts during waking and either ceased to discharge entirely or discharged at a low rate during slow wave sleep. We suggest that OFF cell discharge functions to suppress pain-evoked reactions during sleep, whereas ON cell discharge facilitates pain-evoked responses during waking.  (+info)

MST neuronal responses to heading direction during pursuit eye movements. (4/2220)

As you move through the environment, you see a radial pattern of visual motion with a focus of expansion (FOE) that indicates your heading direction. When self-movement is combined with smooth pursuit eye movements, the turning of the eye distorts the retinal image of the FOE but somehow you still can perceive heading. We studied neurons in the medial superior temporal area (MST) of monkey visual cortex, recording responses to FOE stimuli presented during fixation and smooth pursuit eye movements. Almost all neurons showed significant changes in their FOE selective responses during pursuit eye movements. However, the vector average of all the neuronal responses indicated the direction of the FOE during both fixation and pursuit. Furthermore, the amplitude of the net vector increased with increasing FOE eccentricity. We conclude that neuronal population encoding in MST might contribute to pursuit-tolerant heading perception.  (+info)

Visuomotor processing as reflected in the directional discharge of premotor and primary motor cortex neurons. (5/2220)

Premotor and primary motor cortical neuronal firing was studied in two monkeys during an instructed delay, pursuit tracking task. The task included a premovement "cue period," during which the target was presented at the periphery of the workspace and moved to the center of the workspace along one of eight directions at one of four constant speeds. The "track period" consisted of a visually guided, error-constrained arm movement during which the animal tracked the target as it moved from the central start box along a line to the opposite periphery of the workspace. Behaviorally, the animals tracked the required directions and speeds with highly constrained trajectories. The eye movements consisted of saccades to the target at the onset of the cue period, followed by smooth pursuit intermingled with saccades throughout the cue and track periods. Initially, an analysis of variance (ANOVA) was used to test for direction and period effects in the firing. Subsequently, a linear regression analysis was used to fit the average firing from the cue and track periods to a cosine model. Directional tuning as determined by a significant fit to the cosine model was a prominent feature of the discharge during both the cue and track periods. However, the directional tuning of the firing of a single cell was not always constant across the cue and track periods. Approximately one-half of the neurons had differences in their preferred directions (PDs) of >45 degrees between cue and track periods. The PD in the cue or track period was not dependent on the target speed. A second linear regression analysis based on calculation of the preferred direction in 20-ms bins (i.e., the PD trajectory) was used to examine on a finer time scale the temporal evolution of this change in directional tuning. The PD trajectories in the cue period were not straight but instead rotated over the workspace to align with the track period PD. Both clockwise and counterclockwise rotations occurred. The PD trajectories were relatively straight during most of the track period. The rotation and eventual convergence of the PD trajectories in the cue period to the preferred direction of the track period may reflect the transformation of visual information into motor commands. The widely dispersed PD trajectories in the cue period would allow targets to be detected over a wide spatial aperture. The convergence of the PD trajectories occurring at the cue-track transition may serve as a "Go" signal to move that was not explicitly supplied by the paradigm. Furthermore, the rotation and convergence of the PD trajectories may provide a mechanism for nonstandard mapping. Standard mapping refers to a sensorimotor transformation in which the stimulus is the object of the reach. Nonstandard mapping is the mapping of an arbitrary stimulus into an arbitrary movement. The shifts in the PD may allow relevant visual information from any direction to be transformed into an appropriate movement direction, providing a neural substrate for nonstandard stimulus-response mappings.  (+info)

Fatal outcome arising from use of a sutureless "corkscrew" epicardial pacing electrode inserted into apex of left ventricle. (6/2220)

A 59-year-old man is described in whom the insertion of an epicardial sutureless "corkscrew" electrode resulted in fatal ventricular perforation. Fatal myocardial perforation can occur with this electrode and the apex of the left ventricle should never be used as the site of insertion. Necropsy also showed that the transvenous right ventricular electrode, inserted one year previously, had penetrated a tricuspid leaflet. This could have accounted for the ensuing pacing failure.  (+info)

Gating of transmission in climbing fibre paths to cerebellar cortical C1 and C3 zones in the rostral paramedian lobule during locomotion in the cat. (7/2220)

1. Climbing fibre field potentials evoked by low intensity (non-noxious) electrical stimulation of the ipsilateral superficial radial nerve have been recorded in the rostral paramedian lobule (PML) in awake cats. Chronically implanted microwires were used to monitor the responses at eight different C1 and C3 zone sites during quiet rest and during steady walking on a moving belt. The latency and other characteristics of the responses identified them as mediated mainly via the dorsal funiculus-spino-olivocerebellar path (DF-SOCP). 2. At each site, mean size of response (measured as the area under the field, in mV ms) varied systematically during the step cycle without parallel fluctuations in size of the peripheral nerve volley. Largest responses occurred overwhelmingly during the stance phase of the step cycle in the ipsilateral forelimb while smallest responses occurred most frequently during swing. 3. Simultaneous recording from pairs of C1 zone sites located in the anterior lobe (lobule V) and C1 or C3 zone sites in rostral PML revealed markedly different patterns of step-related modulation. 4. The findings shed light on the extent to which the SOCPs projecting to different parts of a given zone can be regarded as functionally uniform and have implications as to their reliability as channels for conveying peripheral signals to the cerebellum during locomotion.  (+info)

Effects of capsaicin pretreatment on expiratory laryngeal closure during pulmonary edema in lambs. (8/2220)

The present study, performed in nonsedated, conscious lambs, consisted of two parts. In the first part, we 1) examined for the first time whether a respiratory response to pulmonary C-fiber stimulation could be elicited in nonsedated newborns and 2) determined whether this response could be abolished by capsaicin pretreatment. Then, by using capsaicin-desensitized lambs, we studied whether pulmonary C fibers were involved in the sustained, active expiratory upper airway closure previously observed during pulmonary edema. Airflow and thyroarytenoid and inferior pharyngeal constrictor muscle electromyographic activities were recorded. In the first set of experiments, a 5-10 microg/kg capsaicin bolus intravenous injection in seven intact lambs consistently led to a typical pulmonary chemoreflex, showing that C fibers are functionally mature in newborn lambs. In the second series of experiments, eight lambs pretreated with 25-50 mg/kg subcutaneous capsaicin did not exhibit any respiratory response to 10-50 microg/kg intravenous capsaicin injection, implicating C fibers in the response. Finally, in the above capsaicin-desensitized lambs, we observed that halothane-induced high-permeability pulmonary edema did not cause the typical response of sustained expiratory upper airway closure seen in the intact lamb. We conclude that functionally mature C fibers are present and responsible for a pulmonary chemoreflex in response to capsaicin intravenous injection in nonsedated lambs. Capsaicin pretreatment abolishes this reflex. Furthermore, the sustained expiratory upper airway closure observed during halothane-induced pulmonary edema in intact nonsedated lambs appears to be related to a reflex involving stimulation of pulmonary C fibers.  (+info)

An electrode is a medical device that can conduct electrical currents and is used to transmit or receive electrical signals, often in the context of medical procedures or treatments. In a medical setting, electrodes may be used for a variety of purposes, such as:

1. Recording electrical activity in the body: Electrodes can be attached to the skin or inserted into body tissues to measure electrical signals produced by the heart, brain, muscles, or nerves. This information can be used to diagnose medical conditions, monitor the effectiveness of treatments, or guide medical procedures.
2. Stimulating nerve or muscle activity: Electrodes can be used to deliver electrical impulses to nerves or muscles, which can help to restore function or alleviate symptoms in people with certain medical conditions. For example, electrodes may be used to stimulate the nerves that control bladder function in people with spinal cord injuries, or to stimulate muscles in people with muscle weakness or paralysis.
3. Administering treatments: Electrodes can also be used to deliver therapeutic treatments, such as transcranial magnetic stimulation (TMS) for depression or deep brain stimulation (DBS) for movement disorders like Parkinson's disease. In these procedures, electrodes are implanted in specific areas of the brain and connected to a device that generates electrical impulses, which can help to regulate abnormal brain activity and improve symptoms.

Overall, electrodes play an important role in many medical procedures and treatments, allowing healthcare professionals to diagnose and treat a wide range of conditions that affect the body's electrical systems.

Implanted electrodes are medical devices that are surgically placed inside the body to interface directly with nerves, neurons, or other electrically excitable tissue for various therapeutic purposes. These electrodes can be used to stimulate or record electrical activity from specific areas of the body, depending on their design and application.

There are several types of implanted electrodes, including:

1. Deep Brain Stimulation (DBS) electrodes: These are placed deep within the brain to treat movement disorders such as Parkinson's disease, essential tremor, and dystonia. DBS electrodes deliver electrical impulses that modulate abnormal neural activity in targeted brain regions.
2. Spinal Cord Stimulation (SCS) electrodes: These are implanted along the spinal cord to treat chronic pain syndromes. SCS electrodes emit low-level electrical pulses that interfere with pain signals traveling to the brain, providing relief for patients.
3. Cochlear Implant electrodes: These are surgically inserted into the cochlea of the inner ear to restore hearing in individuals with severe to profound hearing loss. The electrodes stimulate the auditory nerve directly, bypassing damaged hair cells within the cochlea.
4. Retinal Implant electrodes: These are implanted in the retina to treat certain forms of blindness caused by degenerative eye diseases like retinitis pigmentosa. The electrodes convert visual information from a camera into electrical signals, which stimulate remaining retinal cells and transmit the information to the brain via the optic nerve.
5. Sacral Nerve Stimulation (SNS) electrodes: These are placed near the sacral nerves in the lower back to treat urinary or fecal incontinence and overactive bladder syndrome. SNS electrodes deliver electrical impulses that regulate the function of the affected muscles and nerves.
6. Vagus Nerve Stimulation (VNS) electrodes: These are wrapped around the vagus nerve in the neck to treat epilepsy and depression. VNS electrodes provide intermittent electrical stimulation to the vagus nerve, which has connections to various regions of the brain involved in these conditions.

Overall, implanted electrodes serve as a crucial component in many neuromodulation therapies, offering an effective treatment option for numerous neurological and sensory disorders.

Ion-Selective Electrodes (ISEs) are a type of chemical sensor that measure the activity of specific ions in a solution. They work by converting the chemical response into an electrical signal, which can then be measured and analyzed. The electrode is coated with a membrane that is selectively permeable to a particular ion, allowing for the detection and measurement of that specific ion in the presence of other ions.

ISEs are widely used in various fields such as clinical chemistry, biomedical research, environmental monitoring, and industrial process control. In medical diagnostics, ISEs are commonly used to measure the levels of ions such as sodium, potassium, chloride, and calcium in biological samples like blood, urine, and cerebrospinal fluid.

The response of an ISE is based on Nernst's equation, which relates the electrical potential across the membrane to the activity of the ion being measured. The selectivity of the electrode for a particular ion is determined by the type of membrane used, and the choice of membrane depends on the application and the specific ions to be measured.

Overall, Ion-Selective Electrodes are important tools in medical diagnostics and research, providing accurate and reliable measurements of ion activity in biological systems.

Electrochemistry is a branch of chemistry that deals with the interconversion of electrical energy and chemical energy. It involves the study of chemical processes that cause electrons to move, resulting in the transfer of electrical charge, and the reverse processes by which electrical energy can be used to drive chemical reactions. This field encompasses various phenomena such as the generation of electricity from chemical sources (as in batteries), the electrolysis of substances, and corrosion. Electrochemical reactions are fundamental to many technologies, including energy storage and conversion, environmental protection, and medical diagnostics.

Electrochemical techniques are a group of analytical methods used in chemistry and biochemistry that involve the study of chemical processes that cause electrons to move. These techniques use an electrochemical cell, which consists of two electrodes (a working electrode and a counter electrode) immersed in an electrolyte solution. An electrical potential is applied between the electrodes, which drives redox reactions to occur at the electrode surfaces. The resulting current that flows through the cell can be measured and related to the concentration of analytes in the solution.

There are several types of electrochemical techniques, including:

1. Voltammetry: This technique measures the current that flows through the cell as a function of the applied potential. There are several types of voltammetry, including cyclic voltammetry, differential pulse voltammetry, and square wave voltammetry.
2. Amperometry: This technique measures the current that flows through the cell at a constant potential.
3. Potentiometry: This technique measures the potential difference between the working electrode and a reference electrode at zero current flow.
4. Impedance spectroscopy: This technique measures the impedance of the electrical circuit formed by the electrochemical cell as a function of frequency.

Electrochemical techniques are widely used in various fields, such as environmental monitoring, pharmaceuticals, food analysis, and biomedical research. They offer several advantages, including high sensitivity, selectivity, and simplicity, making them a powerful tool for chemical analysis.

A microelectrode is a small electrode with dimensions ranging from several micrometers to a few tens of micrometers in diameter. They are used in various biomedical applications, such as neurophysiological studies, neuromodulation, and brain-computer interfaces. In these applications, microelectrodes serve to record electrical activity from individual or small groups of neurons or deliver electrical stimuli to specific neural structures with high spatial resolution.

Microelectrodes can be fabricated using various materials, including metals (e.g., tungsten, stainless steel, platinum), metal alloys, carbon fibers, and semiconductor materials like silicon. The design of microelectrodes may vary depending on the specific application, with some common types being sharpened metal wires, glass-insulated metal microwires, and silicon-based probes with multiple recording sites.

The development and use of microelectrodes have significantly contributed to our understanding of neural function in health and disease, enabling researchers and clinicians to investigate the underlying mechanisms of neurological disorders and develop novel therapies for conditions such as Parkinson's disease, epilepsy, and hearing loss.

Potentiometry is a method used in analytical chemistry to measure the potential (or voltage) difference between two electrodes, which reflects the concentration of an ion or a particular molecule in a solution. It involves setting up an electrochemical cell with two electrodes: a working electrode and a reference electrode. The working electrode is immersed in the test solution and its potential is measured against the stable potential of the reference electrode.

The Nernst equation can be used to relate the potential difference to the concentration of the analyte, allowing for quantitative analysis. Potentiometry is often used to measure the activity or concentration of ions such as H+, Na+, K+, and Cl-, as well as other redox-active species.

In medical testing, potentiometry can be used to measure the concentration of certain ions in biological fluids such as blood, urine, or sweat. For example, it can be used to measure the pH of a solution (the concentration of H+ ions) or the concentration of glucose in blood using a glucometer.

Fluorocarbon polymers are a type of synthetic polymeric material that contain carbon-fluorine bonds. These materials are known for their chemical inertness, high stability, and resistance to heat, chemicals, and water. They are often used in various medical applications such as in the coating of medical devices, implants, and drug delivery systems due to their biocompatibility and non-reactive properties.

Fluorocarbon polymers can be classified into two main categories: perfluoropolymers and fluoropolymers. Perfluoropolymers contain only carbon and fluorine atoms, while fluoropolymers contain other elements such as hydrogen, oxygen, or nitrogen in addition to carbon and fluorine.

Examples of fluorocarbon polymers used in medical applications include polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), and ethylene tetrafluoroethylene (ETFE). These materials have a wide range of properties that make them useful in various medical applications, such as low coefficient of friction, high electrical resistance, and excellent chemical resistance.

I'm sorry for any confusion, but "graphite" is not a medical term. It is a mineral form of carbon that is used in various applications, such as pencils, lubricants, and batteries. If you have any medical questions or terms you would like defined, I'd be happy to help!

Biosensing techniques refer to the methods and technologies used to detect and measure biological molecules or processes, typically through the use of a physical device or sensor. These techniques often involve the conversion of a biological response into an electrical signal that can be measured and analyzed. Examples of biosensing techniques include electrochemical biosensors, optical biosensors, and piezoelectric biosensors.

Electrochemical biosensors measure the electrical current or potential generated by a biochemical reaction at an electrode surface. This type of biosensor typically consists of a biological recognition element, such as an enzyme or antibody, that is immobilized on the electrode surface and interacts with the target analyte to produce an electrical signal.

Optical biosensors measure changes in light intensity or wavelength that occur when a biochemical reaction takes place. This type of biosensor can be based on various optical principles, such as absorbance, fluorescence, or surface plasmon resonance (SPR).

Piezoelectric biosensors measure changes in mass or frequency that occur when a biomolecule binds to the surface of a piezoelectric crystal. This type of biosensor is based on the principle that piezoelectric materials generate an electrical charge when subjected to mechanical stress, and this charge can be used to detect changes in mass or frequency that are proportional to the amount of biomolecule bound to the surface.

Biosensing techniques have a wide range of applications in fields such as medicine, environmental monitoring, food safety, and biodefense. They can be used to detect and measure a variety of biological molecules, including proteins, nucleic acids, hormones, and small molecules, as well as to monitor biological processes such as cell growth or metabolism.

Equipment design, in the medical context, refers to the process of creating and developing medical equipment and devices, such as surgical instruments, diagnostic machines, or assistive technologies. This process involves several stages, including:

1. Identifying user needs and requirements
2. Concept development and brainstorming
3. Prototyping and testing
4. Design for manufacturing and assembly
5. Safety and regulatory compliance
6. Verification and validation
7. Training and support

The goal of equipment design is to create safe, effective, and efficient medical devices that meet the needs of healthcare providers and patients while complying with relevant regulations and standards. The design process typically involves a multidisciplinary team of engineers, clinicians, designers, and researchers who work together to develop innovative solutions that improve patient care and outcomes.

Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.

In a medical context, electric stimulation may be used for various purposes such as:

1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.

It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.

I believe there may be some confusion in your question. Gold is typically a chemical element with the symbol Au and atomic number 79. It is a dense, soft, malleable, and ductile metal. It is one of the least reactive chemical elements and is solid under standard conditions.

However, if you are referring to "Gold" in the context of medical terminology, it may refer to:

1. Gold salts: These are a group of compounds that contain gold and are used in medicine for their anti-inflammatory properties. They have been used in the treatment of rheumatoid arthritis, although they have largely been replaced by newer drugs with fewer side effects.
2. Gold implants: In some cases, a small amount of gold may be surgically implanted into the eye to treat conditions such as age-related macular degeneration or diabetic retinopathy. The gold helps to hold the retina in place and can improve vision in some patients.
3. Gold thread embedment: This is an alternative therapy used in traditional Chinese medicine, where gold threads are embedded into the skin or acupuncture points for therapeutic purposes. However, there is limited scientific evidence to support its effectiveness.

I hope this information helps! If you have any further questions, please let me know.

Cochlear implants are medical devices that are surgically implanted in the inner ear to help restore hearing in individuals with severe to profound hearing loss. These devices bypass the damaged hair cells in the inner ear and directly stimulate the auditory nerve, allowing the brain to interpret sound signals. Cochlear implants consist of two main components: an external processor that picks up and analyzes sounds from the environment, and an internal receiver/stimulator that receives the processed information and sends electrical impulses to the auditory nerve. The resulting patterns of electrical activity are then perceived as sound by the brain. Cochlear implants can significantly improve communication abilities, language development, and overall quality of life for individuals with profound hearing loss.

Conductometry is a method used to measure the electrical conductivity of a solution, which can change in the presence of certain ions or chemical reactions. In conductometry, a conductivity probe or electrode is placed in the solution and an electrical current is passed through it. The resistance of the solution is then measured and converted into a measurement of conductivity.

Conductometry is often used to monitor chemical reactions that produce or consume ions, such as acid-base titrations, oxidation-reduction reactions, and complexation reactions. By measuring changes in conductivity over time, researchers can gain insights into the rate and extent of these reactions.

In medical research, conductometry may be used to study the electrical properties of biological tissues, such as skin or blood, or to monitor chemical processes in the body, such as the metabolism of drugs or other substances. However, it is not a commonly used diagnostic tool in clinical medicine.

Cochlear implantation is a surgical procedure in which a device called a cochlear implant is inserted into the inner ear (cochlea) of a person with severe to profound hearing loss. The implant consists of an external component, which includes a microphone, processor, and transmitter, and an internal component, which includes a receiver and electrode array.

The microphone picks up sounds from the environment and sends them to the processor, which analyzes and converts the sounds into electrical signals. These signals are then transmitted to the receiver, which stimulates the electrode array in the cochlea. The electrodes directly stimulate the auditory nerve fibers, bypassing the damaged hair cells in the inner ear that are responsible for normal hearing.

The brain interprets these electrical signals as sound, allowing the person to perceive and understand speech and other sounds. Cochlear implantation is typically recommended for people who do not benefit from traditional hearing aids and can significantly improve communication, quality of life, and social integration for those with severe to profound hearing loss.

Electric impedance is a measure of opposition to the flow of alternating current (AC) in an electrical circuit or component, caused by both resistance (ohmic) and reactance (capacitive and inductive). It is expressed as a complex number, with the real part representing resistance and the imaginary part representing reactance. The unit of electric impedance is the ohm (Ω).

In the context of medical devices, electric impedance may be used to measure various physiological parameters, such as tissue conductivity or fluid composition. For example, bioelectrical impedance analysis (BIA) uses electrical impedance to estimate body composition, including fat mass and lean muscle mass. Similarly, electrical impedance tomography (EIT) is a medical imaging technique that uses electric impedance to create images of internal organs and tissues.

Immobilized enzymes refer to enzymes that have been restricted or fixed in a specific location and are unable to move freely. This is typically achieved through physical or chemical methods that attach the enzyme to a solid support or matrix. The immobilization of enzymes can provide several advantages, including increased stability, reusability, and ease of separation from the reaction mixture.

Immobilized enzymes are widely used in various industrial applications, such as biotransformations, biosensors, and diagnostic kits. They can also be used for the production of pharmaceuticals, food additives, and other fine chemicals. The immobilization techniques include adsorption, covalent binding, entrapment, and cross-linking.

Adsorption involves physically attaching the enzyme to a solid support through weak forces such as van der Waals interactions or hydrogen bonding. Covalent binding involves forming chemical bonds between the enzyme and the support matrix. Entrapment involves encapsulating the enzyme within a porous matrix, while cross-linking involves chemically linking multiple enzyme molecules together to form a stable structure.

Overall, immobilized enzymes offer several advantages over free enzymes, including improved stability, reusability, and ease of separation from the reaction mixture, making them valuable tools in various industrial applications.

In the context of medical definitions, 'carbon' is not typically used as a standalone term. Carbon is an element with the symbol C and atomic number 6, which is naturally abundant in the human body and the environment. It is a crucial component of all living organisms, forming the basis of organic compounds, such as proteins, carbohydrates, lipids, and nucleic acids (DNA and RNA).

Carbon forms strong covalent bonds with various elements, allowing for the creation of complex molecules that are essential to life. In this sense, carbon is a fundamental building block of life on Earth. However, it does not have a specific medical definition as an isolated term.

Electroencephalography (EEG) is a medical procedure that records electrical activity in the brain. It uses small, metal discs called electrodes, which are attached to the scalp with paste or a specialized cap. These electrodes detect tiny electrical charges that result from the activity of brain cells, and the EEG machine then amplifies and records these signals.

EEG is used to diagnose various conditions related to the brain, such as seizures, sleep disorders, head injuries, infections, and degenerative diseases like Alzheimer's or Parkinson's. It can also be used during surgery to monitor brain activity and ensure that surgical procedures do not interfere with vital functions.

EEG is a safe and non-invasive procedure that typically takes about 30 minutes to an hour to complete, although longer recordings may be necessary in some cases. Patients are usually asked to relax and remain still during the test, as movement can affect the quality of the recording.

Electricity is not a medical term, but rather a fundamental aspect of physics and science. It refers to the form of energy resulting from the existence of charged particles such as electrons or protons, either statically as an accumulation of charge or dynamically as a current.

However, in the context of medical procedures and treatments, electricity is often used to stimulate nerves or muscles, destroy tissue through processes like electrocoagulation, or generate images of internal structures using methods like electrocardiography (ECG) or electroencephalography (EEG). In these cases, a clear medical definition would be:

The use of electric currents or fields in medical procedures for therapeutic or diagnostic purposes.

Electric stimulation therapy, also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is a therapeutic treatment that uses electrical impulses to stimulate muscles and nerves. The electrical signals are delivered through electrodes placed on the skin near the target muscle group or nerve.

The therapy can be used for various purposes, including:

1. Pain management: Electric stimulation can help reduce pain by stimulating the release of endorphins, which are natural painkillers produced by the body. It can also help block the transmission of pain signals to the brain.
2. Muscle rehabilitation: NMES can be used to prevent muscle atrophy and maintain muscle tone in individuals who are unable to move their muscles due to injury or illness, such as spinal cord injuries or stroke.
3. Improving circulation: Electric stimulation can help improve blood flow and reduce swelling by contracting the muscles and promoting the movement of fluids in the body.
4. Wound healing: NMES can be used to promote wound healing by increasing blood flow, reducing swelling, and improving muscle function around the wound site.
5. Muscle strengthening: Electric stimulation can be used to strengthen muscles by causing them to contract and relax repeatedly, which can help improve muscle strength and endurance.

It is important to note that electric stimulation therapy should only be administered under the guidance of a trained healthcare professional, as improper use can cause harm or discomfort.

Equipment Failure Analysis is a process of identifying the cause of failure in medical equipment or devices. This involves a systematic examination and evaluation of the equipment, its components, and operational history to determine why it failed. The analysis may include physical inspection, chemical testing, and review of maintenance records, as well as assessment of design, manufacturing, and usage factors that may have contributed to the failure.

The goal of Equipment Failure Analysis is to identify the root cause of the failure, so that corrective actions can be taken to prevent similar failures in the future. This is important in medical settings to ensure patient safety and maintain the reliability and effectiveness of medical equipment.

Bioelectric energy sources refer to the electrical energy generated through biological processes within living organisms. This energy is produced by the conversion of chemical energy into electrical energy, typically through the use of cell membranes and ions. A common example of a bioelectric energy source is the action potential generated by nerve cells, or neurons, in order to communicate signals throughout the body. Another example is the electrical energy generated by cardiac muscle cells during each heartbeat. These endogenous electrical signals can be harnessed and used for various medical and therapeutic purposes, such as in the use of pacemakers and cochlear implants. Additionally, there is ongoing research into developing bioelectric devices that can interface with living tissues to monitor or manipulate biological processes, such as tissue regeneration and cancer treatment.

Deep brain stimulation (DBS) is a surgical procedure that involves the implantation of a medical device called a neurostimulator, which sends electrical impulses to specific targets in the brain. The impulses help to regulate abnormal brain activity, and can be used to treat a variety of neurological conditions, including Parkinson's disease, essential tremor, dystonia, and obsessive-compulsive disorder.

During the procedure, electrodes are implanted into the brain and connected to the neurostimulator, which is typically implanted in the chest. The neurostimulator can be programmed to deliver electrical impulses at varying frequencies, amplitudes, and pulse widths, depending on the specific needs of the patient.

DBS is generally considered a safe and effective treatment option for many patients with neurological conditions, although it does carry some risks, such as infection, bleeding, and hardware complications. It is typically reserved for patients who have not responded well to other forms of treatment, or who experience significant side effects from medication.

An action potential is a brief electrical signal that travels along the membrane of a nerve cell (neuron) or muscle cell. It is initiated by a rapid, localized change in the permeability of the cell membrane to specific ions, such as sodium and potassium, resulting in a rapid influx of sodium ions and a subsequent efflux of potassium ions. This ion movement causes a brief reversal of the electrical potential across the membrane, which is known as depolarization. The action potential then propagates along the cell membrane as a wave, allowing the electrical signal to be transmitted over long distances within the body. Action potentials play a crucial role in the communication and functioning of the nervous system and muscle tissue.

Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.

EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.

EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.

Tin compounds refer to chemical substances that contain tin (Sn) combined with one or more other elements. Tin can form various types of compounds, including oxides, sulfides, halides, and organometallic compounds. These compounds have different properties and uses depending on the other element(s) they are combined with.

For example:

* Tin (IV) oxide (SnO2) is a white powder used as an opacifying agent in glass and ceramics, as well as a component in some types of batteries.
* Tin (II) sulfide (SnS) is a black or brown solid used in the manufacture of some types of semiconductors.
* Tin (IV) chloride (SnCl4) is a colorless liquid used as a catalyst in the production of polyvinyl chloride (PVC) and other plastics.
* Organotin compounds, such as tributyltin (TBT), are used as biocides and antifouling agents in marine paints. However, they have been found to be toxic to aquatic life and are being phased out in many countries.

Silver compounds refer to chemical substances that combine silver (Ag) with one or more other elements. In the medical context, silver compounds are known for their antimicrobial properties and have been used in various medical applications such as wound dressings, creams, and coatings on medical devices.

Some examples of silver compounds include:

* Silver sulfadiazine (AgSD): a common topical antibiotic used to prevent and treat bacterial infections in burn wounds.
* Silver nitrate (AgNO3): a strong antiseptic used to treat wounds, skin infections, and eye conditions such as neonatal conjunctivitis.
* Silver chloride (AgCl): a compound used in some wound dressings for its antimicrobial properties.
* Silver proteinate: a silver compound that is often used in dietary supplements and claimed to have immune-boosting and anti-inflammatory effects, although its efficacy is not well established.

It's important to note that while silver compounds can be effective antimicrobial agents, they can also have potential side effects such as skin irritation, discoloration, and in some cases, argyria (a bluish-gray discoloration of the skin caused by excessive accumulation of silver). Therefore, they should be used under the guidance of a healthcare professional.

Electrophysiology is a branch of medicine that deals with the electrical activities of the body, particularly the heart. In a medical context, electrophysiology studies (EPS) are performed to assess abnormal heart rhythms (arrhythmias) and to evaluate the effectiveness of certain treatments, such as medication or pacemakers.

During an EPS, electrode catheters are inserted into the heart through blood vessels in the groin or neck. These catheters can record the electrical activity of the heart and stimulate it to help identify the source of the arrhythmia. The information gathered during the study can help doctors determine the best course of treatment for each patient.

In addition to cardiac electrophysiology, there are also other subspecialties within electrophysiology, such as neuromuscular electrophysiology, which deals with the electrical activity of the nervous system and muscles.

I'm sorry for any confusion, but "Platinum" is not a medical term. Platinum is a chemical element with the symbol Pt and atomic number 78. It is a dense, malleable, ductile, highly unreactive, precious, silverish-white transition metal.

However, in the field of oncology, platinum-based compounds are used as chemotherapeutic drugs. These include:

1. Cisplatin: This is a platinum-containing drug that is used to treat various types of cancers such as testicular cancer, ovarian cancer, bladder cancer, and others. It works by forming crosslinks with the DNA of cancer cells, which disrupts their function and leads to cell death.

2. Carboplatin: This is another platinum-based chemotherapy drug that is used to treat various types of cancers such as ovarian cancer, lung cancer, and others. It is less toxic than cisplatin but has similar mechanisms of action.

3. Oxaliplatin: This is a third platinum-based chemotherapy drug that is used to treat colon cancer and rectal cancer. Like the other two drugs, it forms crosslinks with DNA and disrupts cell function leading to cell death.

These drugs are not made of pure platinum but contain platinum compounds that have been synthesized for medical use.

Dielectric spectroscopy is a type of material characterization technique that measures the dielectric properties of a material as a function of frequency. The dielectric property of a material refers to its ability to store electrical energy in the form of polarization when an external electric field is applied. In dielectric spectroscopy, the material's response to an alternating electric field is measured, and the resulting complex permittivity (which includes both real and imaginary components) is used to characterize the material's dielectric behavior.

The technique involves applying a small amplitude AC voltage to the material while measuring the current flow through it. The frequency of the applied voltage can be varied over a wide range, typically from millihertz to gigahertz. By analyzing the phase shift and amplitude of the resulting current, the complex permittivity of the material can be determined as a function of frequency.

Dielectric spectroscopy is widely used in materials science, physics, chemistry, and biology to study the structure, dynamics, and composition of various materials, including polymers, ceramics, glasses, colloids, and biological tissues. The technique can provide valuable information about the material's molecular mobility, relaxation processes, conductivity, and other dielectric properties, which can be used for quality control, process monitoring, and fundamental research.

In the context of medicine and medical devices, calibration refers to the process of checking, adjusting, or confirming the accuracy of a measurement instrument or system. This is typically done by comparing the measurements taken by the device being calibrated to those taken by a reference standard of known accuracy. The goal of calibration is to ensure that the medical device is providing accurate and reliable measurements, which is critical for making proper diagnoses and delivering effective treatment. Regular calibration is an important part of quality assurance and helps to maintain the overall performance and safety of medical devices.

The subdural space is a potential space between the dura mater, which is the outermost of the three meninges covering the brain and spinal cord, and the arachnoid mater, which is the middle meningeal layer. This space normally contains a thin film of fluid, but when it becomes filled with blood (subdural hematoma) or pus (subdural empyema), it can cause significant neurological problems due to increased pressure on the brain. The subdural space can also become widened in certain conditions such as dementia or hydrocephalus, leading to a condition called subdural hygroma.

Computer-assisted signal processing is a medical term that refers to the use of computer algorithms and software to analyze, interpret, and extract meaningful information from biological signals. These signals can include physiological data such as electrocardiogram (ECG) waves, electromyography (EMG) signals, electroencephalography (EEG) readings, or medical images.

The goal of computer-assisted signal processing is to automate the analysis of these complex signals and extract relevant features that can be used for diagnostic, monitoring, or therapeutic purposes. This process typically involves several steps, including:

1. Signal acquisition: Collecting raw data from sensors or medical devices.
2. Preprocessing: Cleaning and filtering the data to remove noise and artifacts.
3. Feature extraction: Identifying and quantifying relevant features in the signal, such as peaks, troughs, or patterns.
4. Analysis: Applying statistical or machine learning algorithms to interpret the extracted features and make predictions about the underlying physiological state.
5. Visualization: Presenting the results in a clear and intuitive way for clinicians to review and use.

Computer-assisted signal processing has numerous applications in healthcare, including:

* Diagnosing and monitoring cardiac arrhythmias or other heart conditions using ECG signals.
* Assessing muscle activity and function using EMG signals.
* Monitoring brain activity and diagnosing neurological disorders using EEG readings.
* Analyzing medical images to detect abnormalities, such as tumors or fractures.

Overall, computer-assisted signal processing is a powerful tool for improving the accuracy and efficiency of medical diagnosis and monitoring, enabling clinicians to make more informed decisions about patient care.

I'm sorry for any confusion, but "Polyvinyl Chloride" (PVC) is not a medical term. It is a type of synthetic plastic polymer material. PVC is commonly used in various industrial, commercial, and consumer products, such as pipes, cable insulation, clothing, and inflatable items.

If you have any medical concerns or questions, please provide them, and I would be happy to help you find a relevant answer.

Ferrocyanides are salts or complex ions containing the ferrocyanide ion (Fe(CN)2-4). The ferrocyanide ion is a stable, soluble, and brightly colored complex that contains iron in the +2 oxidation state coordinated to four cyanide ligands. Ferrocyanides are commonly used in various industrial applications such as water treatment, chemical synthesis, and photography due to their stability and reactivity. However, they can be toxic if ingested or inhaled in large quantities, so proper handling and disposal procedures should be followed.

Glucose oxidase (GOD) is an enzyme that catalyzes the oxidation of D-glucose to D-glucono-1,5-lactone, while reducing oxygen to hydrogen peroxide in the process. This reaction is a part of the metabolic pathway in some organisms that convert glucose into energy. The systematic name for this enzyme is D-glucose:oxygen 1-oxidoreductase.

Glucose oxidase is commonly found in certain fungi, such as Aspergillus niger, and it has various applications in industry, medicine, and research. For instance, it's used in the production of glucose sensors for monitoring blood sugar levels, in the detection and quantification of glucose in food and beverages, and in the development of biosensors for environmental monitoring.

It's worth noting that while glucose oxidase has many applications, it should not be confused with glutathione peroxidase, another enzyme involved in the reduction of hydrogen peroxide to water.

Carbon nanotubes (CNTs) are defined in medical literature as hollow, cylindrical structures composed of rolled graphene sheets, with diameters typically measuring on the nanoscale (ranging from 1 to several tens of nanometers) and lengths that can reach several micrometers. They can be single-walled (SWCNTs), consisting of a single layer of graphene, or multi-walled (MWCNTs), composed of multiple concentric layers of graphene.

Carbon nanotubes have unique mechanical, electrical, and thermal properties that make them promising for various biomedical applications, such as drug delivery systems, biosensors, and tissue engineering scaffolds. However, their potential toxicity and long-term effects on human health are still under investigation, particularly concerning their ability to induce oxidative stress, inflammation, and genotoxicity in certain experimental settings.

Electric countershock, also known as defibrillation, is a medical procedure that uses an electric current to restore normal heart rhythm in certain types of cardiac arrhythmias, such as ventricular fibrillation or pulseless ventricular tachycardia. The procedure involves delivering a therapeutic dose of electrical energy to the heart through electrodes placed on the chest wall or directly on the heart. This electric current helps to depolarize a large number of cardiac cells simultaneously, which can help to interrupt the abnormal electrical activity in the heart and allow the normal conduction system to regain control and restore a normal rhythm. Electric countershock is typically delivered using an automated external defibrillator (AED) or a manual defibrillator, and it is a critical component of advanced cardiac life support (ACLS).

The Scala Tympani is a part of the inner ear's bony labyrinth, specifically within the cochlea. It is one of the two channels (the other being the Scala Vestibuli) that make up the bony duct of the cochlea, through which sound waves are transmitted to the inner ear.

The Scala Tympani starts at the round window, which is a membrane-covered opening located on the cochlea's outer wall. It runs parallel to the Scala Vestibuli and connects with it at the helicotrema, a small opening at the apex or tip of the cochlea.

When sound waves reach the inner ear, they cause vibrations in the fluid-filled Scala Tympani and Scala Vestibuli, which stimulate hair cells within the organ of Corti, leading to the conversion of mechanical energy into electrical signals that are then transmitted to the brain via the auditory nerve.

It's important to note that any damage or dysfunction in the Scala Tympani or other parts of the inner ear can lead to hearing loss or other auditory disorders.

I believe there might be a misunderstanding in your question. "Electronics" is not a medical term, but rather a branch of physics and engineering that deals with the design, construction, and operation of electronic devices and systems. It involves the study and application of electrical properties of materials, components, and systems, and how they can be used to process, transmit, and store information and energy.

However, electronics have numerous applications in the medical field, such as in diagnostic equipment, monitoring devices, surgical tools, and prosthetics. In these contexts, "electronics" refers to the specific electronic components or systems that are used for medical purposes.

A neural prosthesis is a type of medical device that is designed to assist or replace the function of impaired nervous system structures. These devices can be used to stimulate nerves and restore sensation, movement, or other functions that have been lost due to injury or disease. They may also be used to monitor neural activity and provide feedback to the user or to a external device.

Neural prostheses can take many forms, depending on the specific function they are intended to restore. For example, a cochlear implant is a type of neural prosthesis that is used to restore hearing in people with severe to profound hearing loss. The device consists of a microphone, a processor, and a array of electrodes that are implanted in the inner ear. Sound is converted into electrical signals by the microphone and processor, and these signals are then used to stimulate the remaining nerve cells in the inner ear, allowing the user to hear sounds.

Other examples of neural prostheses include deep brain stimulation devices, which are used to treat movement disorders such as Parkinson's disease; retinal implants, which are used to restore vision in people with certain types of blindness; and sacral nerve stimulators, which are used to treat urinary incontinence.

It is important to note that neural prostheses are not intended to cure or fully reverse the underlying condition that caused the impairment, but rather to help restore some level of function and improve the user's quality of life.

Electrolysis is a medical procedure that involves the use of electrical current to permanently remove hair growth. It works by passing a thin, solid metal electrode (called a probe) into the natural opening of the hair follicle and applying an electrical charge to destroy the hair root. This process can be used to remove hair from any part of the body, including the face, legs, arms, underarms, and bikini area.

During electrolysis, a trained professional called an electrologist inserts a small needle into the hair follicle and applies a mild electrical current. The current heats up and destroys the hair root, preventing future growth. Multiple treatments are usually necessary to achieve permanent hair removal, as only one or two hairs can be treated at a time.

Electrolysis is considered a safe and effective method for permanent hair removal, but it can cause some discomfort during and after treatment. Common side effects include redness, swelling, and tenderness in the treated area. These side effects typically resolve within a few hours to a few days after treatment.

It's important to note that electrolysis should only be performed by a licensed and trained electrologist. Improper technique can cause scarring, infection, or other complications. Before undergoing electrolysis, it's recommended to consult with a dermatologist or other healthcare provider to discuss the risks and benefits of the procedure.

I'm sorry for any confusion, but "Glass" is not a medical term. Glass is a non-crystalline amorphous solid that is often transparent and has various uses in everyday life, including medical devices and equipment. If you have any questions related to medical terminology or concepts, please provide them, and I'll be happy to help.

A visual prosthesis, also known as a retinal implant or bionic eye, is a medical device that aims to restore some functional vision in individuals who have severe visual impairment or blindness due to certain eye conditions such as retinitis pigmentosa or age-related macular degeneration.

The prosthesis works by electrically stimulating the remaining viable nerve cells in the retina, which then transmit the signals to the brain via the optic nerve. The device typically consists of a camera that captures visual information, a processor that converts the images into electrical signals, and an electrode array that is implanted onto the surface of the retina.

The electrical stimulation of the retinal cells creates patterns of light in the individual's visual field, allowing them to perceive shapes, edges, and movements. While the level of visual acuity achieved with current visual prostheses is still limited, they can significantly improve the quality of life for some individuals by enabling them to perform tasks such as recognizing objects, navigating their environment, and identifying facial expressions.

Loudness perception refers to the subjective experience of the intensity or volume of a sound, which is a psychological response to the physical property of sound pressure level. It is a measure of how loud or soft a sound seems to an individual, and it can be influenced by various factors such as frequency, duration, and the context in which the sound is heard.

The perception of loudness is closely related to the concept of sound intensity, which is typically measured in decibels (dB). However, while sound intensity is an objective physical measurement, loudness is a subjective experience that can vary between individuals and even for the same individual under different listening conditions.

Loudness perception is a complex process that involves several stages of auditory processing, including mechanical transduction of sound waves by the ear, neural encoding of sound information in the auditory nerve, and higher-level cognitive processes that interpret and modulate the perceived loudness of sounds. Understanding the mechanisms underlying loudness perception is important for developing hearing aids, cochlear implants, and other assistive listening devices, as well as for diagnosing and treating various hearing disorders.

Flow Injection Analysis (FIA) is not a medical term, but a technique used in analytical chemistry. However, I can provide you with the definition of this term:

Flow Injection Analysis (FIA) is a method for automated, continuous monitoring and quantitative analysis of chemical substances. It involves the injection of a sample into a flowing carrier stream, which transports it to a detector after mixing and reaction in a flow-through cell or system. The analyte interacts with reagents to produce a signal that can be measured and related to the concentration of the substance being analyzed. FIA is widely used for environmental monitoring, quality control, process control, and clinical analysis.

Evoked potentials (EPs) are medical tests that measure the electrical activity in the brain or spinal cord in response to specific sensory stimuli, such as sight, sound, or touch. These tests are often used to help diagnose and monitor conditions that affect the nervous system, such as multiple sclerosis, brainstem tumors, and spinal cord injuries.

There are several types of EPs, including:

1. Visual Evoked Potentials (VEPs): These are used to assess the function of the visual pathway from the eyes to the back of the brain. A patient is typically asked to look at a patterned image or flashing light while electrodes placed on the scalp record the electrical responses.
2. Brainstem Auditory Evoked Potentials (BAEPs): These are used to evaluate the function of the auditory nerve and brainstem. Clicking sounds are presented to one or both ears, and electrodes placed on the scalp measure the response.
3. Somatosensory Evoked Potentials (SSEPs): These are used to assess the function of the peripheral nerves and spinal cord. Small electrical shocks are applied to a nerve at the wrist or ankle, and electrodes placed on the scalp record the response as it travels up the spinal cord to the brain.
4. Motor Evoked Potentials (MEPs): These are used to assess the function of the motor pathways in the brain and spinal cord. A magnetic or electrical stimulus is applied to the brain or spinal cord, and electrodes placed on a muscle measure the response as it travels down the motor pathway.

EPs can help identify abnormalities in the nervous system that may not be apparent through other diagnostic tests, such as imaging studies or clinical examinations. They are generally safe, non-invasive procedures with few risks or side effects.

Hydrogen-ion concentration, also known as pH, is a measure of the acidity or basicity of a solution. It is defined as the negative logarithm (to the base 10) of the hydrogen ion activity in a solution. The standard unit of measurement is the pH unit. A pH of 7 is neutral, less than 7 is acidic, and greater than 7 is basic.

In medical terms, hydrogen-ion concentration is important for maintaining homeostasis within the body. For example, in the stomach, a high hydrogen-ion concentration (low pH) is necessary for the digestion of food. However, in other parts of the body such as blood, a high hydrogen-ion concentration can be harmful and lead to acidosis. Conversely, a low hydrogen-ion concentration (high pH) in the blood can lead to alkalosis. Both acidosis and alkalosis can have serious consequences on various organ systems if not corrected.

Polarography is a type of electrochemical analysis technique used to determine the concentration of an ion or electron-transferring species in a solution. It involves measuring the current that flows through an electrode as the voltage is varied, which can provide information about the redox potential and the number of electrons transferred during a reaction. The technique is particularly useful for analyzing complex mixtures and for detecting trace amounts of substances.

In polarography, a dropping mercury electrode (DME) is typically used as the working electrode. As the mercury droplets fall from the electrode, they create fresh surfaces for analysis, which helps to minimize interference from surface-adsorbed species. The DME is immersed in a solution containing the analyte along with a supporting electrolyte, and a potential is applied between the DME and a reference electrode.

As the potential is scanned, reduction or oxidation of the analyte occurs at the DME surface, leading to a current that can be measured. The resulting polarogram (a plot of current vs. voltage) shows peaks or waves corresponding to the redox potentials of the analyte, which can be used to identify and quantify the species present in the solution.

Polarography is a sensitive and selective technique that has been widely used in fields such as environmental analysis, pharmaceuticals, and biochemistry. However, it has largely been replaced by more modern electrochemical techniques, such as cyclic voltammetry and differential pulse voltammetry, which offer higher sensitivity and better resolution of complex mixtures.

Artificial membranes are synthetic or man-made materials that possess properties similar to natural biological membranes, such as selective permeability and barrier functions. These membranes can be designed to control the movement of molecules, ions, or cells across them, making them useful in various medical and biotechnological applications.

Examples of artificial membranes include:

1. Dialysis membranes: Used in hemodialysis for patients with renal failure, these semi-permeable membranes filter waste products and excess fluids from the blood while retaining essential proteins and cells.
2. Hemofiltration membranes: Utilized in extracorporeal circuits to remove larger molecules, such as cytokines or inflammatory mediators, from the blood during critical illnesses or sepsis.
3. Drug delivery systems: Artificial membranes can be used to encapsulate drugs, allowing for controlled release and targeted drug delivery in specific tissues or cells.
4. Tissue engineering: Synthetic membranes serve as scaffolds for cell growth and tissue regeneration, guiding the formation of new functional tissues.
5. Biosensors: Artificial membranes can be integrated into biosensing devices to selectively detect and quantify biomolecules, such as proteins or nucleic acids, in diagnostic applications.
6. Microfluidics: Artificial membranes are used in microfluidic systems for lab-on-a-chip applications, enabling the manipulation and analysis of small volumes of fluids for various medical and biological purposes.

"Medical electronics" refers to the field of electronics that is specifically designed for medical applications. This can include a wide range of devices and systems, such as:

1. Medical imaging equipment, such as X-ray machines, CT scanners, MRI machines, and ultrasound machines.
2. Patient monitoring equipment, such as heart rate monitors, blood pressure monitors, and oxygen saturation monitors.
3. Therapeutic devices, such as pacemakers, defibrillators, and deep brain stimulators.
4. Laboratory equipment, such as DNA sequencers, mass spectrometers, and microarray scanners.
5. Wearable health technology, such as fitness trackers, smartwatches, and continuous glucose monitors.
6. Telemedicine systems that enable remote consultations and patient monitoring.

Medical electronics must meet strict regulatory requirements to ensure safety, effectiveness, and reliability. These devices often require specialized electronic components, such as sensors, signal processing circuits, and power management circuits, that are designed to operate in the challenging environments found in medical settings. Medical electronics engineers must have a deep understanding of both electronics and medical applications to design and develop these complex systems.

Deafness is a hearing loss that is so severe that it results in significant difficulty in understanding or comprehending speech, even when using hearing aids. It can be congenital (present at birth) or acquired later in life due to various causes such as disease, injury, infection, exposure to loud noises, or aging. Deafness can range from mild to profound and may affect one ear (unilateral) or both ears (bilateral). In some cases, deafness may be accompanied by tinnitus, which is the perception of ringing or other sounds in the ears.

Deaf individuals often use American Sign Language (ASL) or other forms of sign language to communicate. Some people with less severe hearing loss may benefit from hearing aids, cochlear implants, or other assistive listening devices. Deafness can have significant social, educational, and vocational implications, and early intervention and appropriate support services are critical for optimal development and outcomes.

The 'Limit of Detection' (LOD) is a term used in laboratory medicine and clinical chemistry to describe the lowest concentration or quantity of an analyte (the substance being measured) that can be reliably distinguished from zero or blank value, with a specified level of confidence. It is typically expressed as a concentration or amount and represents the minimum amount of analyte that must be present in a sample for the assay to produce a response that is statistically different from a blank or zero calibrator.

The LOD is an important parameter in analytical method validation, as it helps to define the range of concentrations over which the assay can accurately and precisely measure the analyte. It is determined based on statistical analysis of the data generated during method development and validation, taking into account factors such as the variability of the assay and the signal-to-noise ratio.

It's important to note that LOD should not be confused with the 'Limit of Quantification' (LOQ), which is the lowest concentration or quantity of an analyte that can be measured with acceptable precision and accuracy. LOQ is typically higher than LOD, as it requires a greater level of confidence in the measurement.

Electroplating is not a medical term, but rather a process used in the industrial field. It refers to the process of coating an electrically conductive object with a thin layer of metal through the use of an electrical current. This process involves immersing the object in a solution containing dissolved ions of the metal to be deposited, and then passing an electric current through the solution. The object serves as the cathode, and the metal ions are reduced at its surface, forming a thin layer of pure metal.

While electroplating is not directly related to medicine, it does have some medical applications. For example, medical devices such as pacemakers or implantable defibrillators may be coated with gold or other metals through electroplating to improve their biocompatibility and reduce the risk of corrosion or rejection by the body. Similarly, dental restorations may be electroplated with precious metals to enhance their strength and durability.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Oxidation-Reduction (redox) reactions are a type of chemical reaction involving a transfer of electrons between two species. The substance that loses electrons in the reaction is oxidized, and the substance that gains electrons is reduced. Oxidation and reduction always occur together in a redox reaction, hence the term "oxidation-reduction."

In biological systems, redox reactions play a crucial role in many cellular processes, including energy production, metabolism, and signaling. The transfer of electrons in these reactions is often facilitated by specialized molecules called electron carriers, such as nicotinamide adenine dinucleotide (NAD+/NADH) and flavin adenine dinucleotide (FAD/FADH2).

The oxidation state of an element in a compound is a measure of the number of electrons that have been gained or lost relative to its neutral state. In redox reactions, the oxidation state of one or more elements changes as they gain or lose electrons. The substance that is oxidized has a higher oxidation state, while the substance that is reduced has a lower oxidation state.

Overall, oxidation-reduction reactions are fundamental to the functioning of living organisms and are involved in many important biological processes.

Stereotaxic techniques are minimally invasive surgical procedures used in neuroscience and neurology that allow for precise targeting and manipulation of structures within the brain. These methods use a stereotactic frame, which is attached to the skull and provides a three-dimensional coordinate system to guide the placement of instruments such as electrodes, cannulas, or radiation sources. The main goal is to reach specific brain areas with high precision and accuracy, minimizing damage to surrounding tissues. Stereotaxic techniques are widely used in research, diagnosis, and treatment of various neurological disorders, including movement disorders, pain management, epilepsy, and psychiatric conditions.

I'm sorry for any confusion, but "Silver" is not a medical term. It is a chemical element with the symbol Ag and atomic number 47. Silver is a soft, white, lustrous transition metal that occurs in its pure, free form (native silver) as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite.

In the medical field, silver compounds have been used for their antimicrobial properties. For example, silver sulfadiazine is a common topical cream used to prevent or treat wound infections. Colloidal silver, a suspension of silver particles in a liquid, has also been promoted as a dietary supplement and alternative treatment for various conditions, but its effectiveness and safety are not well-established.

Electric conductivity, also known as electrical conductance, is a measure of a material's ability to allow the flow of electric current through it. It is usually measured in units of Siemens per meter (S/m) or ohm-meters (Ω-m).

In medical terms, electric conductivity can refer to the body's ability to conduct electrical signals, which is important for various physiological processes such as nerve impulse transmission and muscle contraction. Abnormalities in electrical conductivity can be associated with various medical conditions, including neurological disorders and heart diseases.

For example, in electrocardiography (ECG), the electric conductivity of the heart is measured to assess its electrical activity and identify any abnormalities that may indicate heart disease. Similarly, in electromyography (EMG), the electric conductivity of muscles is measured to diagnose neuromuscular disorders.

Catheter ablation is a medical procedure in which specific areas of heart tissue that are causing arrhythmias (irregular heartbeats) are destroyed or ablated using heat energy (radiofrequency ablation), cold energy (cryoablation), or other methods. The procedure involves threading one or more catheters through the blood vessels to the heart, where the tip of the catheter can be used to selectively destroy the problematic tissue. Catheter ablation is often used to treat atrial fibrillation, atrial flutter, and other types of arrhythmias that originate in the heart's upper chambers (atria). It may also be used to treat certain types of arrhythmias that originate in the heart's lower chambers (ventricles), such as ventricular tachycardia.

The goal of catheter ablation is to eliminate or reduce the frequency and severity of arrhythmias, thereby improving symptoms and quality of life. In some cases, it may also help to reduce the risk of stroke and other complications associated with arrhythmias. Catheter ablation is typically performed by a specialist in heart rhythm disorders (electrophysiologist) in a hospital or outpatient setting under local anesthesia and sedation. The procedure can take several hours to complete, depending on the complexity of the arrhythmia being treated.

It's important to note that while catheter ablation is generally safe and effective, it does carry some risks, such as bleeding, infection, damage to nearby structures, and the possibility of recurrent arrhythmias. Patients should discuss the potential benefits and risks of the procedure with their healthcare provider before making a decision about treatment.

Iridium is not a medical term, but rather a chemical element with the symbol Ir and atomic number 77. It's a transition metal that is part of the platinum group. Iridium has no known biological role in humans or other organisms, and it is not used in medical treatments or diagnoses.

However, iridium is sometimes mentioned in the context of geological time scales because iridium-rich layers in rock formations are associated with major extinction events, such as the one that marked the end of the Cretaceous period 65 million years ago. The leading hypothesis for this association is that large asteroid impacts can create iridium-rich vapor plumes that settle onto the Earth's surface and leave a distinct layer in the rock record.

"Cat" is a common name that refers to various species of small carnivorous mammals that belong to the family Felidae. The domestic cat, also known as Felis catus or Felis silvestris catus, is a popular pet and companion animal. It is a subspecies of the wildcat, which is found in Europe, Africa, and Asia.

Domestic cats are often kept as pets because of their companionship, playful behavior, and ability to hunt vermin. They are also valued for their ability to provide emotional support and therapy to people. Cats are obligate carnivores, which means that they require a diet that consists mainly of meat to meet their nutritional needs.

Cats are known for their agility, sharp senses, and predatory instincts. They have retractable claws, which they use for hunting and self-defense. Cats also have a keen sense of smell, hearing, and vision, which allow them to detect prey and navigate their environment.

In medical terms, cats can be hosts to various parasites and diseases that can affect humans and other animals. Some common feline diseases include rabies, feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and toxoplasmosis. It is important for cat owners to keep their pets healthy and up-to-date on vaccinations and preventative treatments to protect both the cats and their human companions.

Membrane potential is the electrical potential difference across a cell membrane, typically for excitable cells such as nerve and muscle cells. It is the difference in electric charge between the inside and outside of a cell, created by the selective permeability of the cell membrane to different ions. The resting membrane potential of a typical animal cell is around -70 mV, with the interior being negative relative to the exterior. This potential is generated and maintained by the active transport of ions across the membrane, primarily through the action of the sodium-potassium pump. Membrane potentials play a crucial role in many physiological processes, including the transmission of nerve impulses and the contraction of muscle cells.

Electrophoresis, Microchip is a laboratory technique that separates and analyzes mixed populations of molecules such as DNA, RNA, or proteins based on their size and electrical charge. This method uses a microchip, typically made of glass or silicon, with multiple tiny channels etched into its surface.

The sample containing the mixture of molecules is loaded into one end of the channel and an electric field is applied, causing the negatively charged molecules to migrate towards the positively charged end of the channel. The smaller or lighter molecules move faster than the larger or heavier ones, resulting in their separation as they travel through the channel.

The use of microchips allows for rapid and high-resolution separation of molecules, making it a valuable tool in various fields such as molecular biology, genetics, and diagnostics. It can be used to detect genetic variations, gene expression levels, and protein modifications, among other applications.

Electric power supplies are devices that convert electrical energy from a source into a form suitable for powering various types of equipment or devices. They can include a wide range of products such as batteries, generators, transformers, and rectifiers. The main function of an electric power supply is to maintain a stable voltage and current to the load, despite variations in the input voltage or changes in the load's electrical characteristics.

In medical terminology, electric power supplies are used in various medical devices such as diagnostic equipment, therapeutic machines, and monitoring systems. They provide a reliable source of power to these devices, ensuring their proper functioning and enabling accurate measurements and treatments. In some cases, medical power supplies may also include features such as uninterruptible power supply (UPS) systems or emergency power-off functions to ensure patient safety in the event of a power failure or other electrical issues.

Electroporation is a medical procedure that involves the use of electrical fields to create temporary pores or openings in the cell membrane, allowing for the efficient uptake of molecules, drugs, or genetic material into the cell. This technique can be used for various purposes, including delivering genes in gene therapy, introducing drugs for cancer treatment, or transforming cells in laboratory research. The electrical pulses are carefully controlled to ensure that they are strong enough to create pores in the membrane without causing permanent damage to the cell. After the electrical field is removed, the pores typically close and the cell membrane returns to its normal state.

I believe there might be a misunderstanding in your question. "Dogs" is not a medical term or condition. It is the common name for a domesticated carnivore of the family Canidae, specifically the genus Canis, which includes wolves, foxes, and other extant and extinct species of mammals. Dogs are often kept as pets and companions, and they have been bred in a wide variety of forms and sizes for different purposes, such as hunting, herding, guarding, assisting police and military forces, and providing companionship and emotional support.

If you meant to ask about a specific medical condition or term related to dogs, please provide more context so I can give you an accurate answer.

Surface properties in the context of medical science refer to the characteristics and features of the outermost layer or surface of a biological material or structure, such as cells, tissues, organs, or medical devices. These properties can include physical attributes like roughness, smoothness, hydrophobicity or hydrophilicity, and electrical conductivity, as well as chemical properties like charge, reactivity, and composition.

In the field of biomaterials science, understanding surface properties is crucial for designing medical implants, devices, and drug delivery systems that can interact safely and effectively with biological tissues and fluids. Surface modifications, such as coatings or chemical treatments, can be used to alter surface properties and enhance biocompatibility, improve lubricity, reduce fouling, or promote specific cellular responses like adhesion, proliferation, or differentiation.

Similarly, in the field of cell biology, understanding surface properties is essential for studying cell-cell interactions, cell signaling, and cell behavior. Cells can sense and respond to changes in their environment, including variations in surface properties, which can influence cell shape, motility, and function. Therefore, characterizing and manipulating surface properties can provide valuable insights into the mechanisms of cellular processes and offer new strategies for developing therapies and treatments for various diseases.

Auditory evoked potentials (AEP) are medical tests that measure the electrical activity in the brain in response to sound stimuli. These tests are often used to assess hearing function and neural processing in individuals, particularly those who cannot perform traditional behavioral hearing tests.

There are several types of AEP tests, including:

1. Brainstem Auditory Evoked Response (BAER) or Brainstem Auditory Evoked Potentials (BAEP): This test measures the electrical activity generated by the brainstem in response to a click or tone stimulus. It is often used to assess the integrity of the auditory nerve and brainstem pathways, and can help diagnose conditions such as auditory neuropathy and retrocochlear lesions.
2. Middle Latency Auditory Evoked Potentials (MLAEP): This test measures the electrical activity generated by the cortical auditory areas of the brain in response to a click or tone stimulus. It is often used to assess higher-level auditory processing, and can help diagnose conditions such as auditory processing disorders and central auditory dysfunction.
3. Long Latency Auditory Evoked Potentials (LLAEP): This test measures the electrical activity generated by the cortical auditory areas of the brain in response to a complex stimulus, such as speech. It is often used to assess language processing and cognitive function, and can help diagnose conditions such as learning disabilities and dementia.

Overall, AEP tests are valuable tools for assessing hearing and neural function in individuals who cannot perform traditional behavioral hearing tests or who have complex neurological conditions.

Neurophysiology is a branch of physiology that deals with the study of the functioning of the nervous system and its components, including the neurons, neurotransmitters, and electrical signals that transmit information within the nervous system. It involves the examination of various aspects such as nerve impulse transmission, sensory processes, muscle activation, and brain function using techniques like electroencephalography (EEG), electromyography (EMG), and nerve conduction studies. The findings from neurophysiological studies can be applied to diagnose and manage neurological disorders and injuries.

In the context of medical definitions, polymers are large molecules composed of repeating subunits called monomers. These long chains of monomers can have various structures and properties, depending on the type of monomer units and how they are linked together. In medicine, polymers are used in a wide range of applications, including drug delivery systems, medical devices, and tissue engineering scaffolds. Some examples of polymers used in medicine include polyethylene, polypropylene, polystyrene, polyvinyl chloride (PVC), and biodegradable polymers such as polylactic acid (PLA) and polycaprolactone (PCL).

The subthalamic nucleus (STN) is a small, lens-shaped structure located in the basal ganglia of the brain. It plays a crucial role in motor control and has been identified as a key target for deep brain stimulation surgery in the treatment of Parkinson's disease and other movement disorders.

The STN is involved in the regulation of movement, balance, and posture, and helps to filter and coordinate signals that are sent from the cerebral cortex to the thalamus and then on to the motor neurons in the brainstem and spinal cord. In Parkinson's disease, abnormal activity in the STN can contribute to symptoms such as tremors, rigidity, and difficulty initiating movements.

Deep brain stimulation of the STN involves implanting electrodes into the nucleus and delivering electrical impulses that help to regulate its activity. This can lead to significant improvements in motor function and quality of life for some people with Parkinson's disease.

Reproducibility of results in a medical context refers to the ability to obtain consistent and comparable findings when a particular experiment or study is repeated, either by the same researcher or by different researchers, following the same experimental protocol. It is an essential principle in scientific research that helps to ensure the validity and reliability of research findings.

In medical research, reproducibility of results is crucial for establishing the effectiveness and safety of new treatments, interventions, or diagnostic tools. It involves conducting well-designed studies with adequate sample sizes, appropriate statistical analyses, and transparent reporting of methods and findings to allow other researchers to replicate the study and confirm or refute the results.

The lack of reproducibility in medical research has become a significant concern in recent years, as several high-profile studies have failed to produce consistent findings when replicated by other researchers. This has led to increased scrutiny of research practices and a call for greater transparency, rigor, and standardization in the conduct and reporting of medical research.

I'm sorry for any confusion, but "nanowires" is not a medical term. It is a term used in the field of materials science and nanotechnology. Nanowires are one-dimensional structures with a diameter of 1-100 nanometers (nm) and an aspect ratio (length/diameter) greater than 1000. They have unique electrical, mechanical, and optical properties that make them useful in various applications such as electronics, sensors, energy storage, and biomedical devices.

I believe you are asking for a medical explanation or definition of the term "diamond" in a medical context. However, I should clarify that "diamond" is not a commonly used medical term for a specific disease, condition, or diagnostic feature. It's essential to provide more information if it relates to a particular medical concept or usage.

In general, the term "diamond" refers to a clear and colorless form of carbon with a crystalline structure in which each carbon atom is bonded to four other carbon atoms, forming a tetrahedral shape. It's widely known for its use as a valuable gemstone due to its exceptional hardness, brilliance, and fire.

However, there are some tangential medical connections to the term "diamond." For example:

1. Diamond Blackfan anemia (DBA): A rare congenital bone marrow failure disorder characterized by a decrease in red blood cell production. It is named after Drs. Louis Diamond and Kenneth Blackfan, who first described it.
2. Turner syndrome with XY sex chromosomes: A rare genetic condition where an individual has only one functional X chromosome instead of the typical pair (XX) found in females. Occasionally, these individuals may have a Y chromosome fragment, often referred to as "mosaic Turner syndrome with XY cells" or "XY gonadal dysgenesis." In this context, the term "XY" is sometimes metaphorically described as a "genetic male's 'diamond in the rough'" due to its rarity and unique characteristics.

If you have more information about how the term "diamond" is being used in your specific medical context, I would be happy to help further clarify or provide additional details.

Neurons, also known as nerve cells or neurocytes, are specialized cells that constitute the basic unit of the nervous system. They are responsible for receiving, processing, and transmitting information and signals within the body. Neurons have three main parts: the dendrites, the cell body (soma), and the axon. The dendrites receive signals from other neurons or sensory receptors, while the axon transmits these signals to other neurons, muscles, or glands. The junction between two neurons is called a synapse, where neurotransmitters are released to transmit the signal across the gap (synaptic cleft) to the next neuron. Neurons vary in size, shape, and structure depending on their function and location within the nervous system.

Electrochemotherapy is a medical treatment that combines the use of certain drugs with electrical pulses to increase the permeability of cell membranes, allowing for enhanced uptake of the drugs into cells. This approach is often used in the treatment of cancer, particularly in cases where the tumor is localized and not responsive to other forms of therapy.

The drugs most commonly used in electrochemotherapy are cytotoxic agents, such as bleomycin or cisplatin, which can effectively kill cancer cells when delivered in high concentrations. However, these drugs typically have poor membrane permeability, making it difficult to achieve therapeutic levels inside the cells.

To overcome this challenge, electrochemotherapy applies short, intense electrical pulses to the tumor site, creating temporary pores in the cell membranes. This allows for increased drug uptake and improved distribution of the cytotoxic agents within the cancer cells. The electrical pulses also have a direct effect on the cancer cells, further contributing to their destruction.

The benefits of electrochemotherapy include its ability to treat tumors with minimal invasiveness, reduced side effects compared to traditional chemotherapy, and potential synergy between the electrical pulses and cytotoxic drugs for improved treatment outcomes. Electrochemotherapy is often used in palliative care or as an adjunct to other cancer treatments, such as surgery, radiation therapy, or immunotherapy.

I'm sorry for any confusion, but "Solar Energy" is not a term typically used in medical definitions. Solar energy refers to the energy that comes from the sun and can be captured and converted into thermal or electrical energy. It is not a medical concept or treatment. If you have any questions related to health or medicine, I'd be happy to try to help answer those for you!

The correction of hearing impairment refers to the various methods and technologies used to improve or restore hearing function in individuals with hearing loss. This can include the use of hearing aids, cochlear implants, and other assistive listening devices. Additionally, speech therapy and auditory training may also be used to help individuals with hearing impairment better understand and communicate with others. In some cases, surgical procedures may also be performed to correct physical abnormalities in the ear or improve nerve function. The goal of correction of hearing impairment is to help individuals with hearing loss better interact with their environment and improve their overall quality of life.

The cochlea is a part of the inner ear that is responsible for hearing. It is a spiral-shaped structure that looks like a snail shell and is filled with fluid. The cochlea contains hair cells, which are specialized sensory cells that convert sound vibrations into electrical signals that are sent to the brain.

The cochlea has three main parts: the vestibular canal, the tympanic canal, and the cochlear duct. Sound waves enter the inner ear and cause the fluid in the cochlea to move, which in turn causes the hair cells to bend. This bending motion stimulates the hair cells to generate electrical signals that are sent to the brain via the auditory nerve.

The brain then interprets these signals as sound, allowing us to hear and understand speech, music, and other sounds in our environment. Damage to the hair cells or other structures in the cochlea can lead to hearing loss or deafness.

Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures. These seizures are caused by abnormal electrical activity in the brain, which can result in a wide range of symptoms, including convulsions, loss of consciousness, and altered sensations or behaviors. Epilepsy can have many different causes, including genetic factors, brain injury, infection, or stroke. In some cases, the cause may be unknown.

There are many different types of seizures that can occur in people with epilepsy, and the specific type of seizure will depend on the location and extent of the abnormal electrical activity in the brain. Some people may experience only one type of seizure, while others may have several different types. Seizures can vary in frequency, from a few per year to dozens or even hundreds per day.

Epilepsy is typically diagnosed based on the patient's history of recurrent seizures and the results of an electroencephalogram (EEG), which measures the electrical activity in the brain. Imaging tests such as MRI or CT scans may also be used to help identify any structural abnormalities in the brain that may be contributing to the seizures.

While there is no cure for epilepsy, it can often be effectively managed with medication. In some cases, surgery may be recommended to remove the area of the brain responsible for the seizures. With proper treatment and management, many people with epilepsy are able to lead normal, productive lives.

The heart conduction system is a group of specialized cardiac muscle cells that generate and conduct electrical impulses to coordinate the contraction of the heart chambers. The main components of the heart conduction system include:

1. Sinoatrial (SA) node: Also known as the sinus node, it is located in the right atrium near the entrance of the superior vena cava and functions as the primary pacemaker of the heart. It sets the heart rate by generating electrical impulses at regular intervals.
2. Atrioventricular (AV) node: Located in the interatrial septum, near the opening of the coronary sinus, it serves as a relay station for electrical signals between the atria and ventricles. The AV node delays the transmission of impulses to allow the atria to contract before the ventricles.
3. Bundle of His: A bundle of specialized cardiac muscle fibers that conducts electrical impulses from the AV node to the ventricles. It divides into two main branches, the right and left bundle branches, which further divide into smaller Purkinje fibers.
4. Right and left bundle branches: These are extensions of the Bundle of His that transmit electrical impulses to the respective right and left ventricular myocardium. They consist of specialized conducting tissue with large diameters and minimal resistance, allowing for rapid conduction of electrical signals.
5. Purkinje fibers: Fine, branching fibers that arise from the bundle branches and spread throughout the ventricular myocardium. They are responsible for transmitting electrical impulses to the working cardiac muscle cells, triggering coordinated ventricular contraction.

In summary, the heart conduction system is a complex network of specialized muscle cells responsible for generating and conducting electrical signals that coordinate the contraction of the atria and ventricles, ensuring efficient blood flow throughout the body.

Artificial cardiac pacing is a medical procedure that involves the use of an artificial device to regulate and stimulate the contraction of the heart muscle. This is often necessary when the heart's natural pacemaker, the sinoatrial node, is not functioning properly and the heart is beating too slowly or irregularly.

The artificial pacemaker consists of a small generator that produces electrical impulses and leads that are positioned in the heart to transmit the impulses. The generator is typically implanted just under the skin in the chest, while the leads are inserted into the heart through a vein.

There are different types of artificial cardiac pacing systems, including single-chamber pacemakers, which stimulate either the right atrium or right ventricle, and dual-chamber pacemakers, which stimulate both chambers of the heart. Some pacemakers also have additional features that allow them to respond to changes in the body's needs, such as during exercise or sleep.

Artificial cardiac pacing is a safe and effective treatment for many people with abnormal heart rhythms, and it can significantly improve their quality of life and longevity.

The temporal bone is a paired bone that is located on each side of the skull, forming part of the lateral and inferior walls of the cranial cavity. It is one of the most complex bones in the human body and has several important structures associated with it. The main functions of the temporal bone include protecting the middle and inner ear, providing attachment for various muscles of the head and neck, and forming part of the base of the skull.

The temporal bone is divided into several parts, including the squamous part, the petrous part, the tympanic part, and the styloid process. The squamous part forms the lateral portion of the temporal bone and articulates with the parietal bone. The petrous part is the most medial and superior portion of the temporal bone and contains the inner ear and the semicircular canals. The tympanic part forms the lower and anterior portions of the temporal bone and includes the external auditory meatus or ear canal. The styloid process is a long, slender projection that extends downward from the inferior aspect of the temporal bone and serves as an attachment site for various muscles and ligaments.

The temporal bone plays a crucial role in hearing and balance, as it contains the structures of the middle and inner ear, including the oval window, round window, cochlea, vestibule, and semicircular canals. The stapes bone, one of the three bones in the middle ear, is entirely encased within the petrous portion of the temporal bone. Additionally, the temporal bone contains important structures for facial expression and sensation, including the facial nerve, which exits the skull through the stylomastoid foramen, a small opening in the temporal bone.

I'm sorry for any confusion, but "Finite Element Analysis" (FEA) is not a medical term. It is a computational technique used in engineering and physical sciences. FEA is a computerized method for predicting how a product reacts to real-world forces, vibration, heat, fluid flow, and other physical effects. It's a way that engineers can simulate the performance of a product or system before it is built, which can help reduce costs, improve quality, and shorten the development time.

However, in a medical context, FEA might be used in the field of biomechanical engineering to analyze the mechanical behavior of biological systems, such as bones, joints, or soft tissues, under various loads and conditions. This can help researchers and clinicians better understand the mechanisms of injury, disease, or the effects of treatment, and develop more effective prevention, diagnostic, or therapeutic strategies.

I'm sorry for any confusion, but "Transistors, Electronic" is not a recognized medical term. Transistors are electronic components used in various devices, including medical equipment, to amplify or switch electronic signals and electrical power. They are crucial for the functioning of numerous technologies, such as computers, smartphones, and other digital devices. However, they are not typically described in the context of medical definitions. If you have any questions related to electronics or technology that you believe could be relevant to a medical context, please provide more details so I can give a more accurate response.

Neural conduction is the process by which electrical signals, known as action potentials, are transmitted along the axon of a neuron (nerve cell) to transmit information between different parts of the nervous system. This electrical impulse is generated by the movement of ions across the neuronal membrane, and it propagates down the length of the axon until it reaches the synapse, where it can then stimulate the release of neurotransmitters to communicate with other neurons or target cells. The speed of neural conduction can vary depending on factors such as the diameter of the axon, the presence of myelin sheaths (which act as insulation and allow for faster conduction), and the temperature of the environment.

The auditory threshold is the minimum sound intensity or loudness level that a person can detect 50% of the time, for a given tone frequency. It is typically measured in decibels (dB) and represents the quietest sound that a person can hear. The auditory threshold can be affected by various factors such as age, exposure to noise, and certain medical conditions. Hearing tests, such as pure-tone audiometry, are used to measure an individual's auditory thresholds for different frequencies.

Indicators and reagents are terms commonly used in the field of clinical chemistry and laboratory medicine. Here are their definitions:

1. Indicator: An indicator is a substance that changes its color or other physical properties in response to a chemical change, such as a change in pH, oxidation-reduction potential, or the presence of a particular ion or molecule. Indicators are often used in laboratory tests to monitor or signal the progress of a reaction or to indicate the end point of a titration. A familiar example is the use of phenolphthalein as a pH indicator in acid-base titrations, which turns pink in basic solutions and colorless in acidic solutions.

2. Reagent: A reagent is a substance that is added to a system (such as a sample or a reaction mixture) to bring about a chemical reaction, test for the presence or absence of a particular component, or measure the concentration of a specific analyte. Reagents are typically chemicals with well-defined and consistent properties, allowing them to be used reliably in analytical procedures. Examples of reagents include enzymes, antibodies, dyes, metal ions, and organic compounds. In laboratory settings, reagents are often prepared and standardized according to strict protocols to ensure their quality and performance in diagnostic tests and research applications.

Acoustic stimulation refers to the use of sound waves or vibrations to elicit a response in an individual, typically for the purpose of assessing or treating hearing, balance, or neurological disorders. In a medical context, acoustic stimulation may involve presenting pure tones, speech sounds, or other types of auditory signals through headphones, speakers, or specialized devices such as bone conduction transducers.

The response to acoustic stimulation can be measured using various techniques, including electrophysiological tests like auditory brainstem responses (ABRs) or otoacoustic emissions (OAEs), behavioral observations, or functional imaging methods like fMRI. Acoustic stimulation is also used in therapeutic settings, such as auditory training programs for hearing impairment or vestibular rehabilitation for balance disorders.

It's important to note that acoustic stimulation should be administered under the guidance of a qualified healthcare professional to ensure safety and effectiveness.

Prostheses: Artificial substitutes or replacements for missing body parts, such as limbs, eyes, or teeth. They are designed to restore the function, appearance, or mobility of the lost part. Prosthetic devices can be categorized into several types, including:

1. External prostheses: Devices that are attached to the outside of the body, like artificial arms, legs, hands, and feet. These may be further classified into:
a. Cosmetic or aesthetic prostheses: Primarily designed to improve the appearance of the affected area.
b. Functional prostheses: Designed to help restore the functionality and mobility of the lost limb.
2. Internal prostheses: Implanted artificial parts that replace missing internal organs, bones, or tissues, such as heart valves, hip joints, or intraocular lenses.

Implants: Medical devices or substances that are intentionally placed inside the body to replace or support a missing or damaged biological structure, deliver medication, monitor physiological functions, or enhance bodily functions. Examples of implants include:

1. Orthopedic implants: Devices used to replace or reinforce damaged bones, joints, or cartilage, such as knee or hip replacements.
2. Cardiovascular implants: Devices that help support or regulate heart function, like pacemakers, defibrillators, and artificial heart valves.
3. Dental implants: Artificial tooth roots that are placed into the jawbone to support dental prostheses, such as crowns, bridges, or dentures.
4. Neurological implants: Devices used to stimulate nerves, brain structures, or spinal cord tissues to treat various neurological conditions, like deep brain stimulators for Parkinson's disease or cochlear implants for hearing loss.
5. Ophthalmic implants: Artificial lenses that are placed inside the eye to replace a damaged or removed natural lens, such as intraocular lenses used in cataract surgery.

An artificial pacemaker is a medical device that uses electrical impulses to regulate the beating of the heart. It is typically used when the heart's natural pacemaker, the sinoatrial node, is not functioning properly and the heart rate is too slow or irregular. The pacemaker consists of a small generator that contains a battery and electronic circuits, which are connected to one or more electrodes that are placed in the heart.

The generator sends electrical signals through the electrodes to stimulate the heart muscle and cause it to contract, thereby maintaining a regular heart rhythm. Artificial pacemakers can be programmed to deliver electrical impulses at a specific rate or in response to the body's needs. They are typically implanted in the chest during a surgical procedure and can last for many years before needing to be replaced.

Artificial pacemakers are an effective treatment for various types of bradycardia, which is a heart rhythm disorder characterized by a slow heart rate. Pacemakers can significantly improve symptoms associated with bradycardia, such as fatigue, dizziness, shortness of breath, and fainting spells.

Electric capacitance is a measure of the amount of electrical charge that a body or system can hold for a given electric potential. In other words, it is a measure of the capacity of a body or system to store an electric charge. The unit of electric capacitance is the farad (F), which is defined as the capacitance of a conductor that, when charged with one coulomb of electricity, has a potential difference of one volt between its surfaces.

In medical terms, electric capacitance may be relevant in the context of electrical stimulation therapies, such as transcutaneous electrical nerve stimulation (TENS) or functional electrical stimulation (FES). In these therapies, electrodes are placed on the skin and a controlled electric current is applied to stimulate nerves or muscles. The electric capacitance of the tissue and electrodes can affect the distribution and intensity of the electric field, which in turn can influence the therapeutic effect.

It is important to note that while electric capacitance is a fundamental concept in physics and engineering, it is not a commonly used term in medical practice or research. Instead, terms such as impedance or resistance are more commonly used to describe the electrical properties of biological tissues.

Evoked potentials, visual, also known as visually evoked potentials (VEPs), are electrical responses recorded from the brain following the presentation of a visual stimulus. These responses are typically measured using electroencephalography (EEG) and can provide information about the functioning of the visual pathways in the brain.

There are several types of VEPs, including pattern-reversal VEPs and flash VEPs. Pattern-reversal VEPs are elicited by presenting alternating checkerboard patterns, while flash VEPs are elicited by flashing a light. The responses are typically analyzed in terms of their latency (the time it takes for the response to occur) and amplitude (the size of the response).

VEPs are often used in clinical settings to help diagnose and monitor conditions that affect the visual system, such as multiple sclerosis, optic neuritis, and brainstem tumors. They can also be used in research to study the neural mechanisms underlying visual perception.

Brain mapping is a broad term that refers to the techniques used to understand the structure and function of the brain. It involves creating maps of the various cognitive, emotional, and behavioral processes in the brain by correlating these processes with physical locations or activities within the nervous system. Brain mapping can be accomplished through a variety of methods, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET) scans, electroencephalography (EEG), and others. These techniques allow researchers to observe which areas of the brain are active during different tasks or thoughts, helping to shed light on how the brain processes information and contributes to our experiences and behaviors. Brain mapping is an important area of research in neuroscience, with potential applications in the diagnosis and treatment of neurological and psychiatric disorders.

Psychoacoustics is a branch of psychophysics that deals with the study of the psychological and physiological responses to sound. It involves understanding how people perceive, interpret, and react to different sounds, including speech, music, and environmental noises. This field combines knowledge from various areas such as psychology, acoustics, physics, and engineering to investigate the relationship between physical sound characteristics and human perception. Research in psychoacoustics has applications in fields like hearing aid design, noise control, music perception, and communication systems.

An artifact, in the context of medical terminology, refers to something that is created or introduced during a scientific procedure or examination that does not naturally occur in the patient or specimen being studied. Artifacts can take many forms and can be caused by various factors, including contamination, damage, degradation, or interference from equipment or external sources.

In medical imaging, for example, an artifact might appear as a distortion or anomaly on an X-ray, MRI, or CT scan that is not actually present in the patient's body. This can be caused by factors such as patient movement during the scan, metal implants or other foreign objects in the body, or issues with the imaging equipment itself.

Similarly, in laboratory testing, an artifact might refer to a substance or characteristic that is introduced into a sample during collection, storage, or analysis that can interfere with accurate results. This could include things like contamination from other samples, degradation of the sample over time, or interference from chemicals used in the testing process.

In general, artifacts are considered to be sources of error or uncertainty in medical research and diagnosis, and it is important to identify and account for them in order to ensure accurate and reliable results.

Geobacter is not a medical term, but a genus of delta-proteobacteria that are capable of metal reduction and play a significant role in the biogeochemical cycling of metals in the environment. They are commonly found in soil, freshwater sediments, and groundwater, where they can facilitate the remediation of contaminants such as uranium, technetium, and petroleum products. While Geobacter species have no direct relevance to human medical conditions, understanding their metabolic capabilities and ecological roles can contribute to broader knowledge in microbiology, environmental science, and bioremediation.

Iontophoresis is a medical technique in which a mild electrical current is used to deliver medications through the skin. This process enhances the absorption of medication into the body, allowing it to reach deeper tissues that may not be accessible through topical applications alone. Iontophoresis is often used for local treatment of conditions such as inflammation, pain, or spasms, and is particularly useful in treating conditions affecting the hands and feet, like hyperhidrosis (excessive sweating). The medications used in iontophoresis are typically anti-inflammatory drugs, anesthetics, or corticosteroids.

Electromagnetic fields (EMFs) are invisible forces that result from the interaction between electrically charged objects. They are created by natural phenomena, such as the Earth's magnetic field, as well as by human-made sources, such as power lines, electrical appliances, and wireless communication devices.

EMFs are characterized by their frequency and strength, which determine their potential biological effects. Low-frequency EMFs, such as those produced by power lines and household appliances, have frequencies in the range of 0 to 300 Hz. High-frequency EMFs, such as those produced by wireless communication devices like cell phones and Wi-Fi routers, have frequencies in the range of 100 kHz to 300 GHz.

Exposure to EMFs has been linked to a variety of health effects, including increased risk of cancer, reproductive problems, neurological disorders, and oxidative stress. However, more research is needed to fully understand the potential health risks associated with exposure to EMFs and to establish safe exposure limits.

Neurological models are simplified representations or simulations of various aspects of the nervous system, including its structure, function, and processes. These models can be theoretical, computational, or physical and are used to understand, explain, and predict neurological phenomena. They may focus on specific neurological diseases, disorders, or functions, such as memory, learning, or movement. The goal of these models is to provide insights into the complex workings of the nervous system that cannot be easily observed or understood through direct examination alone.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

Transcutaneous Electrical Nerve Stimulation (TENS) is a non-invasive method of pain relief that involves the use of low-voltage electrical currents. A TENS device, which is usually small and portable, delivers these currents through electrodes that are placed on the skin near the site of pain. The electrical impulses stimulate nerve fibers, which can help to block the transmission of pain signals to the brain, thereby reducing the perception of pain.

TENS is thought to work through a number of different mechanisms, including the gate control theory of pain and the release of endorphins, which are natural painkillers produced by the body. It is generally considered safe, with few side effects, and can be used in conjunction with other forms of pain management.

TENS is often used to treat chronic pain conditions such as arthritis, fibromyalgia, and lower back pain, as well as acute pain from injuries or surgery. However, its effectiveness varies from person to person, and it may not work for everyone. It is important to consult with a healthcare provider before using TENS, particularly if you have any underlying medical conditions or are taking medication that could interact with the electrical currents.

Nanotechnology is not a medical term per se, but it is a field of study with potential applications in medicine. According to the National Nanotechnology Initiative, nanotechnology is defined as "the understanding and control of matter at the nanoscale, at dimensions between approximately 1 and 100 nanometers, where unique phenomena enable novel applications."

In the context of medicine, nanotechnology has the potential to revolutionize the way we diagnose, treat, and prevent diseases. Nanomedicine involves the use of nanoscale materials, devices, or systems for medical applications. These can include drug delivery systems that target specific cells or tissues, diagnostic tools that detect biomarkers at the molecular level, and tissue engineering strategies that promote regeneration and repair.

While nanotechnology holds great promise for medicine, it is still a relatively new field with many challenges to overcome, including issues related to safety, regulation, and scalability.

A chronic electrode implant is an electronic device implanted chronically (for a long period) into the brain or other ... Implantable electrode research also employs many different techniques for surgically implanting the electrodes; the most ... Another recent study addressing the impact of chronically implanted electrodes points that tungsten-coated electrodes seem to ... Recording electrodes, however, must rely on whatever signals are present where they are implanted, and cannot easily be made ...
Some applications require electrodes to be implanted in the animal's nervous system connected to a receiver which is usually ... Three electrodes are implanted; two in the ventral posterolateral nucleus of the thalamus which conveys facial sensory ... "There's got to be a level of discomfort in implanting these electrodes," he says, which may be difficult to justify. Talwar ... Several studies have examined the remote control of rats using micro-electrodes implanted into their brains and rely on ...
Intracranial electrodes consist of conductive electrode arrays implanted on a polymer or silicon, or a wire electrode with an ... Prosthesis in these areas are typically electrodes or electrode arrays. Electrodes, especially stimulating electrodes and the ... Surface chemistry of implantable electrodes proves to be more of a design concern for chronically implanted electrodes as ... Electrode impedance is related to surface area at the interface between the electrode and the tissue. At electrode sites, the ...
The electrodes are implanted as described above. The patient uses a hand-held magnet to turn on and turn off a pulse generator ... by turning off the implanted electrode. Batteries in the generator last about 5 years and can be replaced surgically. DBS is ... A low-frequency current is passed through the electrode to activate the tremor and to confirm proper placement. Once the site ... A small hole is drilled through the skull and a temperature-controlled electrode is inserted into the thalamus. ...
Book electrodes are still considered very bulky. Grill WM, Norman SE, Bellamkonda RV (2009). "Implanted neural interfaces: ... Since the electrode is sutured to the epineurium it is unlikely to damage the nerve trunk. Helicoidal electrodes are placed ... Each slot contains three platinum foils which function as electrodes, anode electrodes and one cathode. The spinal roots of the ... A wide variety of electrode designs have been researched, tested, and manufactured. These electrodes lie on a spectrum varying ...
... the implant sends electrical signals to electrodes in the vagus nerve. The application of this device is being tested an ... In some cases implants contain electronics, e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such ... AAOMS - Dental Implant Surgery ACOG - IUDs and Birth Control Implants: Resource Overview FDA - Implants and Prosthetics ... For example, an implant may be a rod, used to strengthen weak bones. Medical implants are human-made devices, in contrast to a ...
Implanted in Nagle's right precentral gyrus (area of the motor cortex for arm movement), the 96-electrode BrainGate implant ... With electrodes also implanted into his wife's nervous system, they conducted the first direct electronic communication ... In addition, according to the research of Abdulkader et al., (2015), the body may not accept the implanted electrodes and this ... The patient had had severe epilepsy and the electrodes were temporarily implanted to help his physicians localize seizure foci ...
EEG and fMRI do not obtain as strong signals as direct electrode implant. Traditional myoelectric prostheses are unable to ... Response of brain tissue to chronically implanted neural electrodes. J Neurosci Methods. 2005 Oct 15;148(1):1-18. Schwartz AB, ... One hundred and fifteen electrodes were used to record EMG from the pectoral muscle; two electrodes were used to record from ... The electrodes were placed at a distance of 15mm from each other. To remove the artifact caused by body movement, the EMG ...
"Response of brain tissue to chronically implanted neural electrodes". Journal of Neuroscience Methods. 148 (1): 1-18. doi: ...
These electrodes emit high-frequency stimulation to the implanted areas. Bilateral implantation is necessary for symmetric ... An example of this therapy might involve implanting cells genetically modified to express tyrosine hydroxylase which, in the ... Deep brain stimulation involves inserting, via stereotaxic surgery, electrodes into the sensorimotor area of the brain. ...
He had DBS electrodes implanted bilaterally within his central thalamus. More specifically, the DBS electrodes targeted the ... Both electrodes were positioned within the central lateral nucleus, the paralaminar regions of the median dorsalis, and the ... a technique that supplies a small electric current in the brain with non-invasive electrodes, may improve the clinical state of ...
Conducting polymer electrodes for auditory brainstem implants; Journal of Materials Chemistry B. 2015. DOI : 10.1039/c5tb00099h ... "Conducting polymer electrodes for auditory brainstem implants". Journal of Materials Chemistry B. 3 (25): 5021-5027. doi: ... These 3D electrode channel devices fixed to polymer substrates not only provide an innovative tool for in vivo guided axon ... These tiny, flexible electrodes are inserted into cochlea, and deliver electrical pulses along the nerve to transduce sound ...
"Electrical stimulation with non-implanted electrodes for overactive bladder in adults". The Cochrane Database of Systematic ...
The small implant is an electrode array made of platinum electrodes embedded within a nitinol endovascular stent. The device ... Stentrode (Stent-electrode recording array) is a small stent-mounted electrode array permanently implanted into a blood vessel ... Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an ... Cortical implant Neuralink Neurorobotics "Brain implant allows mind control of computers in first human trials". New Atlas. 5 ...
These consist of both internal implanted electrodes and magnets and external components. The quality of sound is different than ... A cochlear implant is surgical implantation of a battery powered electronic medical device in the inner ear. Unlike hearing ... In cases of profound or total deafness, a cochlear implant is a specialised hearing aid that may restore a functional level of ... Profound or total hearing loss may be amenable to management by cochlear implants, which stimulate cochlear nerve endings ...
In non-human animals, EEG signals are usually recorded using electrodes implanted in the brain; the majority of theta studies ... In contrast to the situation in rats, where long periods of theta oscillations are easily observed using electrodes implanted ... have involved electrodes implanted in the hippocampus. In humans, because invasive studies are not ethically permissible except ... on human hippocampal theta comes from a few small studies of epileptic patients with intracranially implanted electrodes used ...
The patients answered questions about their mood while the electrodes were implanted. Using the data about the mood and the ... They measured the brain activity of seven patients who had electrodes implanted in their brain to monitor epilepsy. ... "Brain-zapping implants that fight depression inch closer to reality". Science News. 2019-02-10. Retrieved 2019-11-22. Sani, ...
"Factors Affecting Outcomes in Cochlear Implant Recipients Implanted With a Perimodiolar Electrode Array Located in Scala ... Usually, the ENVp of the signal in each channel is transmitted to the implanted electrodes in the form an electrical pulses of ... ISBN 978-1-59756-652-0. Bierer JA, Faulkner KF (April 2010). "Identifying cochlear implant channels with poor electrode-neuron ... Some cochlear implant systems transmit information about TFSp in the channels of the cochlear implants that are tuned to low ...
Nine electrodes had previously been implanted on her skull: two in the front sinus, one in the somatic area, two in the ventral ... Hector had electrodes implanted on his skull so neurological activity could be monitored. Two further rockets with rat payloads ... The cats had electrodes implanted onto their skulls so their neurological activity could be monitored throughout the flight. ... Burgess and Dubbs believe this is due to photos of her with electrodes implanted on her skull and the new animal rights ...
The internal implant sends the signals to the electrode array. The design of the electrode array is the key difference between ... Brain implant Cochlear implant Colletti, L.; Shannon, R.; Colletti, V. (Oct 2012). "Auditory brainstem implants for ... With a cochlear implant, the electrodes positioned in the basal end of the cochlea elicit a higher pitch sensation than those ... Whereas the electrode array for a CI is wire-shaped and is inserted into the cochlea, the electrode array of an ABI is paddle- ...
The team is also considering implanting electrodes directly on nerves. Power Researchers are exploring a hydrogen-peroxide ... A wire coil wrapped over the shoulder supplies wireless power to the implants and relays signals to computers in the prosthetic ... and refine the bulky electrodes used to read electrical signals in muscles. Control System Researchers are experimenting with ...
Leads from the implanted defibrillator pass through a vein into the heart. The leads are attached to electrodes that monitor ... implanted the first AICD in a human patient in February 1980. At the time of the implantation, Mirowski and Mower had ... In fact, the implanted defibrillator system represents an imperfect solution in search of a plausible and practical application ... If something had gone awry, we would have never lived it down." After the device was implanted, physicians induced a cardiac ...
"Transcranial magnetic stimulation and extradural electrodes implanted on secondary auditory cortex for tinnitus suppression". ... somatosensory cortex implants for deafferentation pain; C2 implant for tinnitus, as well as for failed back surgery syndrome; ... He has developed "burst" stimulation, novel stimulation design for brain and spine implants, which is commercialised by Abbott ... body experience with PET scan in a person in whom the out-of-body experience could be elicited by activation of a brain implant ...
He studied monkeys with electrodes implanted in the reticular system and also cortical electrodes. He used evoked responses to ...
The device is implanted into upper chest with the electrodes placed in the neck. First, an incision is made in the neck to ... a feature which is used in the initial implant procedure to aid positioning of the electrode. Despite modern medications ... The electrode is then sutured in place. The main part of the device (also called the pulse generator) is then placed in a ... It uses an implanted device to electrically stimulate baroreceptors in the carotid sinus region. This elicits a reflex response ...
"Rapid and accurate anatomical localization of implanted subdural electrodes in a virtual reality environment". J Neurol Surg a ...
The location where the electrodes are implanted depends on the neurological disorder being treated. The company Neuralink hopes ... that their DBS device will include "as many as 3072 electrodes distributed along 96 threads", and that the procedure to implant ... The neurostimulator is a thin wire with electrodes at its tip. Low levels of electric current are transmitted through the brain ... More complex medical devices can be implanted to treat psychological disorders and illnesses. Anna Wexler, a member of the ...
Believed to be psychotic, he is investigated and electrodes are implanted in his brain. The book continued the preoccupation in ... or The Terminal Man where unexpected behaviors are realized when electrodes are implanted into a person's brain. Mystery ...
Subcutaneous electrodes can be divided into percutaneous and implanted electrodes. The percutaneous electrodes consist of thin ... The other class of subcutaneous electrodes is implanted electrodes. These are permanently implanted in the consumer's body and ... Compared to surface stimulation electrodes, implanted and percutaneous electrodes potentially have higher stimulation ... The drawbacks of the implanted electrodes are they require an invasive surgical procedure to install, and, as is the case with ...
Başkent, Deniz; Shannon, Robert V. (March 2005). "Interactions between cochlear implant electrode insertion depth and frequency ... Later, Shannon has expanded his research to also include auditory brainstem implants and auditory midbrain implants. A key ... auditory brainstem implants, and midbrain implants. Shannon received his B.A. degrees in Mathematics and Psychology from the ... What this paper showed was that the limitation in spectral resolution was not caused by the limited number of electrodes, which ...
A chronic electrode implant is an electronic device implanted chronically (for a long period) into the brain or other ... Implantable electrode research also employs many different techniques for surgically implanting the electrodes; the most ... Another recent study addressing the impact of chronically implanted electrodes points that tungsten-coated electrodes seem to ... Recording electrodes, however, must rely on whatever signals are present where they are implanted, and cannot easily be made ...
A: left shoulder-level radial, median, and ulnar nerves, each shown implanted with a 100-electrode USEA. Insertion support ( ... In this study, we implanted Utah Slanted Electrode Arrays (USEAs) intrafascicularly, at the elbow or shoulder in arm... , Nerve ... USEA implants are shown protected by a custom containment system composed of metal mesh and Kwik-Cast silicone (World Precision ... implanted in arm nerves. Surgical access to all 3 target nerves was achieved through a single surgical site at either the elbow ...
Electrode could reduce the cost of neuromodulation therapy. ... "Typical implants are really stiff, and so as the body moves, ... Injectable, Flexible Electrode Could Replace Rigid Nerve-Stimulating Implants. Electrode could reduce the cost of ... Anatomy Electronic Components Implants & Prosthetics Implants & Prosthetics Medical Medical equipment and supplies Medical, ... making the whole setup less expensive and more adaptable compared to traditional implanted electrodes. ...
Electrode could reduce the cost of neuromodulation therapy. ... "Typical implants are really stiff, and so as the body moves, ... Injectable, Flexible Electrode Could Replace Rigid Nerve-Stimulating Implants. Electrode could reduce the cost of ... Anatomy Electronic Components Implants & Prosthetics Implants & Prosthetics Medical Medical equipment and supplies Medical, ... making the whole setup less expensive and more adaptable compared to traditional implanted electrodes. ...
Speech processing for a multiple-electrode cochlear implant hearing prosthesis. Y. C. Tong*, G. M. Clark, P. M. Seligman, J. F ... Speech processing for a multiple-electrode cochlear implant hearing prosthesis. / Tong, Y. C.; Clark, G. M.; Seligman, P. M. et ... Speech processing for a multiple-electrode cochlear implant hearing prosthesis. Journal of the Acoustical Society of America. ... Speech processing for a multiple-electrode cochlear implant hearing prosthesis. In: Journal of the Acoustical Society of ...
Hypoglossal nerve stimulation uses an implanted device to treat obstructive sleep apnea and may be an alternative to a CPAP ... The cuff electrode fits around a branch of nerve under the tongue, like a tiny cuff. The electrode stimulates the nerves, which ... Allergy to the implant. *Scar tissue forming around the implant, which can make it difficult to remove the implant in the ... Placing the Electrode. *The doctors make a small cut (about 4 centimeters) in the skin under the jaw. ...
... and compared the performance to that of silver wires and a clinical electrode implant. The injectrodes worked just as well as ... Implanting such a device can involve cutting through muscle and nerves (and may require changing a battery every few years). ... Now, a team of biomedical engineers has created a type of electrode that can be injected into the body as a liquid, then harden ... Liquid Electrodes Morph Into Flexible Wires for Neural Stimulation Taffy-like "injectrodes" could replace expensive, rigid ...
Snails with implanted electrodes generate electricity via metabolism. ... Snails with implanted electrodes generate electricity via metabolism.. Megan Scudellari. Mar 14, 2012 , 1 min read. ... Researchers at Clarkson University in Potsdam, New York, have implanted snails with tiny biofuel cells that capture electrical ...
Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes ... Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes ... Relationship between electrode position and temporal modulation sensitivity in cochlear implant users : Are close electrodes ... Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes ...
See how these factors can significantly affect electrode placement and hearing outcomes. ... Why is surgical approach and electrode array design so important? ... cochlear implant rehabilitation themed lesson kits speech and language therapist aural rehabilitation BONEBRIDGE audiology ... electrode arrays supporting your child SYNCHRONY MRI conductive hearing loss children with hearing loss adults with hearing ...
Ultra Cochlear Implant Family & HiRes 90K™ Advantage Implants. ... The HiRes Ultra implant family offers two electrode designs, ... Considerations for design of future cochlear implant electrode arrays: Electrode array stiffness, size, and depth of insertion ... HiRes Ultra Cochlear Implant. The HiRes™ Ultra cochlear implant was developed in collaboration with leading cochlear implant ... Allows for ease of handling and insertion of the electrode.. 3 Gentle electrode curvature. Ensures electrode movement in the ...
... who underwent bilateral implantation of stimulating electrodes in the internal pallidum. At 3-month follow-up, the total Unifie ... Electrodes, Implanted * Female * Follow-Up Studies * Gait / physiology * Globus Pallidus / physiopathology* * Hand / ... who underwent bilateral implantation of stimulating electrodes in the internal pallidum. At 3-month follow-up, the total ...
Implanted electrodes. 研究領域與例子[编辑]. 人工智能[编辑]. *物件識別:討論人類的識別
Determination of the position of nucleus cochlear implant electrodes in the inner ear. Am J Otol. 1994 Sep; 15(5):644-51. ... Determination of the position of nucleus cochlear implant electrodes in the inner ear. ... Determination of the position of nucleus cochlear implant electrodes in the inner ear. ...
Cochlear implants can help many kids with severe hearing loss. Find out how they work and who can get them. ... Sound quality from a cochlear implant is different from that in normal hearing. Thats because a limited number of electrodes ... How Do Cochlear Implants Work?. Cochlear implants have:. *A microphone and speech processor that sit outside the body. The ... What Are Cochlear Implants?. A cochlear implant is a surgically placed device that helps a person with severe hearing loss hear ...
Instead of an electrode array, the company implants two "neurotrophic electrodes"-glass tubes containing tiny wires and a ... have implanted a tiny array of electrodes in the monkeys brain. The electrodes intercept signals from individual neurons in ... Friehs starts by implanting a four-millimeter-square array of 100 electrodes in this region, which is located in the brains ... In those initial trials, the company will implant the electrode array, manufactured by Salt Lake City, UT-based Bionic ...
... these tools present a promising alternative to other types of electrode-based technologies aimed at … ... Electrodes, Implanted* / supply & distribution * Equipment Design / instrumentation * Equipment Design / methods* * Male * Mice ... Main results: We demonstrate the operation of silicon microprobes containing up to 256 electrodes in conjunction with optical ... Currently there is a plethora of electrode-based tools being developed at higher education and research institutions. However, ...
Implanted loop recorders. This is a small monitor that is implanted under the skin on the chest. It can be left in place to ... However, the adhesive of the electrode patches may irritate your skin. This goes away on its own once you remove the patches. ... Loop memory monitor. The electrodes remain attached to your chest, and the monitor constantly records, but does not save, your ... Each type of monitor is slightly different, but most have sensors (called electrodes) to record your ECG. In some models, these ...
... strapping them with the electrodes is silly...they should implant them!. ... I put one electrode on my arm and shocked myself using a remote control. I had been told by the centers employees that it ... If these people have the right to strap these electrodes to kids, why cant we do the same for repeat criminals like pedophiles ... wear up to five electrodes at a time strapped to their arms and legs. The gadget itself is housed in a fanny pack worn by the ...
As a large electrode spacing (up to 500 μm) can be realized in the Implanted-Epi Silicon 3D-Spherical Electrode Detector thanks ... named here as the Implanted-Epi Silicon 3D-Spherical Electrode Detector, is proposed in this work. Epitaxial and ion ... thus the total depletion voltage of Implanted-Epi Silicon 3D-Spherical Electrode Detectors is no longer directively correlated ... Compared with the traditional silicon 3D electrode detectors, the full depletion voltage is greatly reduced and the charge ...
... five electrodes were implanted. Two stainless steel screw electrodes (Plastics One Inc., Roanoke, VA, USA) were implanted into ... One stainless steel screw electrode was implanted in the neck muscle as an EMG recording electrode. Two additional stainless ... Neonatal mice received surgery for placement of EEG electrodes at the age of 30 days, and adult mice at the age of 3 months. ... Following electrode implantation and a post-surgical recovery period, mice were recorded during two consecutive weeks in ...
Thin metal electrodes, inserted initially into the smaller tubes in some experiments, became embedded in the new nerve ... Four of these received implanted electrodes. The animals were anesthetized using a mixture of diazepam and pentobarbital as ... Electrode arrays with up to 100 electrodes have been used for recordings in peripheral nerves [8]. External electrodes, picking ... Large picture: needles (0.4 mm) contacting electrode leads for stimulation via the Pt/Ir electrodes in the smaller tubes. Upper ...
Electrodes implanted. Models animal. Pacemaker artificial. Surgical procedures operative. Swine. Transverse sinuses. ... By using an anterolateral thoracotomy, leads were implanted under visual guidance in the left ventricle and in the right atrium ... Objectives: The present study was design to perform the implant of atrioventricular pacemaker using a new technique for ... Microscopic analysis showed that contact with the electrode had caused thickening of the right atrium, left ventricle and ...
Auditory Brainstem Implant (ABI) Electrode Array. Features 12 active contacts on a soft preshaped silicone paddle. MR ... Cochlear Implants , Electric Acoustic Stimulation , Middle Ear Implant , Bone Conduction Implant , Bone Conduction System , ... What does a cochlear implant sound like?. Can I enjoy music with a cochlear implant?. MRIs and cochlear implants. Product ... Whats more, our cochlear implants are individualized, so that the electrode array fits your individual cochlea. This way, you ...
Electrical pulses delivered through surgically implanted electrodes *Mild vibratory stimuli administered to different parts of ...
Implanting these electrodes requires major surgery. As a consequence, the observed serious side effects in the study -- ... Deuschl et al were comparing drug treatment to implanting electrodes in the STN PLUS drug treatment. What they found is really ... The experimental group had stimulating electrodes implanted into the subthalamic nuclei (STN) of their brain in addition to ... It turns out that because this system is complicated the addition of the STN electrode significantly lowers the amounts of LID ...
... ... Effect of multi-electrode configuration on sensitivity to interaural timing differences in bilateral cochlear-implant users. ... Effect of multi-electrode configuration on sensitivity to interaural timing differences in bilateral cochlear-implant users. ...
Electrodes were implanted in all rats (see below). However, one rat did not survive the surgery and the implanted electrodes in ... Signals from the implanted electrodes were fed into the recording system (Plexon Multichannel Acquisition Processor) and ... four rats received bilateral medial implants, two rats received bilateral ventral implants, and eight rats received one medial ... Electrode holes were identified using light microscopy and plotted onto a rat brain atlas (Paxinos and Watson, 1998). Three- ...
Researchers implanted 14 electrodes into the brains of volunteers with depression. One says it saved his life. ... The team implanted two DBS electrodes on each side of the brain in regions thought to be involved in symptoms of depression. An ... At the start of 2020, he had a total of 14 electrodes implanted across his brain. For nine days, he stayed in a hospital with ... These electrodes were connected to a rechargeable battery implanted in Johns chest. In the years since, the pulses of ...
electrode positioning. *preservation of hearing. *postoperative fitting and device failure analysis. On the following pages you ... The pre- and post-conference workshops will be organised by the cochlear implant manufacturers, who will provide an update on ... The Symposium will focus on recent advances of objective measures in cochlear implants. Both clinical applications and research ... Fourth International Symposium and Workshops: Objective Measures in Cochlear Implants. Medical University of Hannover ...
  • An illustration depicting the UCSF team's implant of a subdural, high-density, multi-electrode array over the area of the sensorimotor cortex that controls speech. (medscape.com)
  • Flexible multi electrode brain-machine interface for recording in the cerebellum. (lu.se)
  • Utah Slanted Electrode Arrays (USEAs) implanted in arm nerves. (researchgate.net)
  • High-count microelectrode arrays implanted in peripheral nerves could restore motor function after spinal cord injury or sensory function after limb loss. (researchgate.net)
  • In this study, we implanted Utah Slanted Electrode Arrays (USEAs) intrafascicularly, at the elbow or shoulder in arm nerves of rhesus monkeys (n = 4) under isoflurane anesthesia. (researchgate.net)
  • Several recent studies have found that electrode array deviation is far more likely with perimodiolar or mid-scala electrode arrays. (medel.pro)
  • Avoiding electrode array deviation isn't always possible-but significantly better rates of successful scala tympani placement can be achieved with the combination of soft surgical techniques and flexible lateral wall arrays. (medel.pro)
  • Electrode arrays with up to 100 electrodes have been used for recordings in peripheral nerves [ 8 ]. (hindawi.com)
  • Neurosurgeons hope to treat some of the most intractable mental disorders by putting advanced arrays of electrodes into patients' brains. (technologyreview.com)
  • Indium tin oxide is a very expensive and brittle material, which cracks easily upon bending, making it unsuitable for flexible electrode arrays. (nature.com)
  • As of yet, neural recordings with completely transparent, flexible electrode arrays, compatible with in vitro and in vivo imaging techniques, have not been demonstrated, to our knowledge. (nature.com)
  • As mentioned above, if there is to be significant progress towards long-term implantable electrodes, an important step is documenting the response of living tissue to electrode implantation in both the acute and chronic timelines. (wikipedia.org)
  • A solution for motor control of an advanced prosthesis could be implantable electrodes with high spatial resolution, which via telemetry could be used to control the artificial limb. (hindawi.com)
  • Implantable electrodes for long term monitoring and interaction with multiple neurons have the potential to provide such information but will only be useful if truly biocompatible, i.e. if they themselves do not cause significant tissue reactions such as inflammation, neuronal loss and glial encapsulation. (lu.se)
  • The implantable electrodes will be used to establish stable high-fidelity communication between neuronal networks in the central nervous system and computers for research and therapeutic purposes. (lu.se)
  • These findings suggest that the methods to reduce channel interaction, e.g., perimodiolar electrode array or current focusing, may only be beneficial for a subgroup of CI users. (wustl.edu)
  • showing translocation of a perimodiolar electrode array from the scala tympani into the scala vestibuli. (medel.pro)
  • The perimodiolar electrode array crosses the basilar membrane and exits the scala tympani (red) in the basal turn, and deviates to the scala vestibuli (blue). (medel.pro)
  • The distance of each electrode from the medial wall (MW) of the cochlea and mid-modiolar axis (MMA) was measured from scans obtained using computerized tomography (CT) imaging. (wustl.edu)
  • Key to the design are the elements that allow a surgeon to easily handle the electrode in the surgical space and insert with minimal trauma to the delicate cochlea structures. (advancedbionics.com)
  • The HiFocus SlimJ electrode can be introduced into the cochlea by a surgeon's preferred approach - by using round window, extended round window, or small cochleostomy, requiring only a 0.8mm opening. (advancedbionics.com)
  • Cochlear implants bypass damaged parts of the cochlea to stimulate the auditory nerve directly. (kidshealth.org)
  • It sends electrical impulses by a thin wire to electrodes placed in the cochlea. (kidshealth.org)
  • That's because a limited number of electrodes take over the work of the thousands of hair cells in a normal cochlea. (kidshealth.org)
  • Threads the wires with the electrodes into the spirals of the cochlea. (kidshealth.org)
  • What's more, our cochlear implants are individualized, so that the electrode array fits your individual cochlea. (medel.com)
  • The implant is a neural stimulator with an electrode array surgically placed near the auditory nerve fibers in the scala tympani of the cochlea. (cdc.gov)
  • Most meningitis cases were associated with an implant with a positioner, a silastic wedge inserted next to the implanted electrode in the cochlea to position the electrode closer to the cochlear nerve endings and thus facilitate electrical signal transmission. (cdc.gov)
  • In part one of this series on electrode array deviation , we looked at how cochlear structures can be damaged when an electrode deviates from the scala tympani into the scala vestibuli. (medel.pro)
  • Round window technique has demonstrated much better prospects of having electrodes fully in the scala tympani. (medel.pro)
  • Fig. 2: Flexible MED-EL lateral wall electrode array placed fully within scala tympani using round window approach. (medel.pro)
  • 7,8,9 HiFocus electrodes are designed with balanced stiffness, which allows for easy insertion within the scala tympani while making it less prone to bend upwards towards the basilar membrane and translocate. (advancedbionics.com)
  • Standard cochlear implantation requires an extended postauricular and scalp incision and large flap, mastoidectomy, facial recess approach, cochleostomy, and insertion of an electrode into the scala tympani. (medscape.com)
  • Monaural chinchillas had electrodes implanted in the inferior colliculus. (cdc.gov)
  • A chronic recording electrode was then stereotaxically implanted into the left inferior colliculus and a ground electrode was implanted just below the dura mater. (cdc.gov)
  • We report here the results of an open prospective study in 9 patients suffering from severe Parkinson's disease with on/off fluctuations and restricted off-period mobility, who underwent bilateral implantation of stimulating electrodes in the internal pallidum. (nih.gov)
  • Thin metal electrodes, inserted initially into the smaller tubes in some experiments, became embedded in the new nerve structures and when stimulated contractions of the distal muscles were observed. (hindawi.com)
  • The technology uses a set of thin metal electrodes implanted on the surface of the spinal cord. (nih.gov)
  • the most critical differences are whether or not the implant is anchored across the skull[22] and the speed of insertion. (wikipedia.org)
  • 23] The overall observed tissue response is caused by a combination of the traumatic injury of electrode insertion and the persistent presence of a foreign body in the neural tissue. (wikipedia.org)
  • Damage caused by electrodes in the short term is caused by the insertion into the tissue. (wikipedia.org)
  • Consequently, research into minimizing this is focused on the geometry of the electrode and the proper technique for insertion. (wikipedia.org)
  • Short term effects of electrode insertion on surrounding tissue have been documented extensively. (wikipedia.org)
  • 2006 study, an ex vivo apparatus was constructed explicitly to study the deformation of and damage to neural tissue during electrode insertion. (wikipedia.org)
  • were implanted in nerves just distal to the brachial plexus (Fig. 1A) and near the elbow (Fig. 1B) by means of a high-speed insertion system (Rousche and Normann 1992). (researchgate.net)
  • To make insertion easy and to provide flexibility for surgeons, the implant is designed for a shallow 1mm ramped recess, requiring minimal drilling to reduce surgery time. (advancedbionics.com)
  • HiFocus electrode contacts are encased in a slim flexible tapered silicone carrier to minimize insertion forces and damage to cochlear structures during surgery. (advancedbionics.com)
  • The HiFocus™ SlimJ electrode is the latest approved electrode technology, designed for ease of handling and insertion. (advancedbionics.com)
  • The main benefit of the gentle curvature next to easy insertion is to ensure electrode movement in the apical direction. (advancedbionics.com)
  • Allows for ease of handling and insertion of the electrode. (advancedbionics.com)
  • Dorsal Column (Spinal Cord) Neurostimulation - The surgical implantation of neurostimulator electrodes within the dura mater (endodural) or the percutaneous insertion of electrodes in the epidural space is covered. (cms.gov)
  • The electrodes intercept signals from individual neurons in the brain, and a specially developed computer algorithm translates these signals into trajectories and velocities for the computer cursor. (technologyreview.com)
  • Neural interface electrodes that can record from neurons in the brain for long periods of time will be of great importance to unravel how the brain accomplishes its functions. (lu.se)
  • A cochlear implant is a surgically placed device that helps a person with severe hearing loss hear sounds. (kidshealth.org)
  • Using implanted electrodes, researchers find individual neurons associated with attaching value to objects. (sciencenews.org)
  • In addition, ongoing work aims at developing a new generation of biocompatible electrodes for highly specific and personalized deep brain stimulation to be used to treat neurological disorders such as chronic pain, motor disorders and epilepsy. (lu.se)
  • Our research aim is to develop a new generation of biocompatible Brain Machine Interfaces (BMI), i.e. electrodes that can be implanted into the brain and spinal cord and be maintained there over long periods of time. (lu.se)
  • Electrodes were constructed from silicon wafers to have three different sharpnesses (interior angle of 5° for sharp, 90° for medium, 150° for blunt). (wikipedia.org)
  • Working with Andrew Shoffstall at Case Western Reserve University and Manfred Franke of Neuronoff Inc. , a California-based biotech company, Ludwig and colleagues developed an electrode consisting of bits of metal and a silicon base-similar to surgical glue-that combine to form a thick liquid. (ieee.org)
  • We demonstrate the operation of silicon microprobes containing up to 256 electrodes in conjunction with optical fibers for optogenetic manipulations or fiber photometry. (nih.gov)
  • A new type of 3D electrode detector, named here as the Implanted-Epi Silicon 3D-Spherical Electrode Detector, is proposed in this work. (mdpi.com)
  • With a type of electrode that can be injected as a liquid and then cure in the body, the researchers have laid the groundwork for a new kind of neural interface system. (medicaldesignbriefs.com)
  • Researchers have created numerous flexible or stretchy electrodes to mold to the shape of, say, brain tissue, but this technology can be injected into the body and fill in cracks and crevices around nerves. (ieee.org)
  • To test their new creation, the researchers injected the material into rats and pigs, and compared the performance to that of silver wires and a clinical electrode implant. (ieee.org)
  • Researchers at Clarkson University in Potsdam, New York, have implanted snails with tiny biofuel cells that capture electrical power from the snail's blood. (the-scientist.com)
  • This eerie feat is possible because the researchers, led by Brown neuroscientist John Donoghue, have implanted a tiny array of electrodes in the monkey's brain. (technologyreview.com)
  • Researchers implanted 14 electrodes into the brains of volunteers with depression. (technologyreview.com)
  • So far the researchers have worked on a microscale, but now when there is a functioning method using flexible electrodes that do not damage the brain, there is increasing interest in trying to make it work on a nanoscale. (lu.se)
  • Super-thin flexible electrodes that can be placed exactly where the researchers want them and that register signals from single, or a few, cells are interesting tools for basic research, but what medical applications are in the pipeline? (lu.se)
  • But to reach critical areas of the body, such as the brain or the spine , many treatments require surgically implanted devices, such as a cuff that wraps around the spinal cord. (ieee.org)
  • A new spinal cord implant helped stroke patients regain movement in their arms and hands. (nih.gov)
  • The hypoglossal nerve stimulator implant is controlled by a hand-held remote that turns the device on and off. (hopkinsmedicine.org)
  • Use of this stimulator involves implantation of electrodes around a selected peripheral nerve. (cms.gov)
  • Limited-incision techniques forgo en face exposure of the parietooccipital cortex completely in favor of a restricted tangential exposure of just the cortical bone necessary to develop a limited well for the thickest portion of the receiver/stimulator package. (medscape.com)
  • We essentially went through the standard repertoire of electrochemical tests to show this acts like a standard wire electrode that could be used to stimulate the nerve," says James Trevathan, a postdoctoral fellow in Ludwig's lab and first author on the study. (medicaldesignbriefs.com)
  • Then they can use a basic transcutaneous electrical nerve stimulation, or TENS, unit - the kind you can buy at a department store or pharmacy - to stimulate the nerve from the surface of the skin, making the whole setup less expensive and more adaptable compared to traditional implanted electrodes. (medicaldesignbriefs.com)
  • Hypoglossal nerve stimulation with an implanted device can help some people manage obstructive sleep apnea without a continuous positive airwave pressure (CPAP) machine. (hopkinsmedicine.org)
  • A hypoglossal nerve stimulation implant is an alternative for patients who cannot tolerate CPAP treatment. (hopkinsmedicine.org)
  • Hypoglossal nerve stimulation is a treatment for obstructive sleep apnea that uses an implant to stimulate a nerve under the tongue to prevent the tongue from blocking the airway. (hopkinsmedicine.org)
  • The cuff electrode fits around a branch of nerve under the tongue, like a tiny cuff. (hopkinsmedicine.org)
  • The electrodes stimulate the auditory nerve. (kidshealth.org)
  • For invasive electrodes, one possibility would be to increase the number of fascicles in a severed nerve. (hindawi.com)
  • Payment may be made under the prosthetic device benefit for implanted peripheral nerve stimulators. (cms.gov)
  • For people 4 years old or older with hard-to-control epileptic seizures, the vagus nerve stimulation system implant may reduce the severity and amount of seizures. (sutterhealth.org)
  • Electrodes are wrapped around the vagus nerve. (sutterhealth.org)
  • The electrodes rub against the surrounding brain tissue, which leads to scarring around the electrode known as a "kill-zone" of dead nerve cells - the outcome is that you have damaged what you want to study. (lu.se)
  • He can, however, say that in cooperation with physicists at the Neuronano Research Centre it has been possible to make and implant a nanoelectrode, an electrode with super-thin nanowires, in the brain of a rat, and that signals were successfully captured from the nerve cells. (lu.se)
  • But as part of a clinical trial, John has benefited from an experimental treatment that involves inserting electrodes deep into his brain to deliver regular pulses of electricity. (technologyreview.com)
  • Deep brain stimulation (DBS) usually involves placing one or two electrodes deep into the brain to deliver pulses of electricity to specific regions. (technologyreview.com)
  • The electrode monitors the pulses sent out by the neurons surrounding it. (technovelgy.com)
  • A chronic electrode implant is an electronic device implanted chronically (for a long period) into the brain or other electrically excitable tissue. (wikipedia.org)
  • Moreover, by embedding the dummy probes in a gelatin matrix that dissolves shortly following implantation, neuronal cell death surrounding chronically (6 weeks) implanted electrodes was, for the first time, abolished. (lu.se)
  • Additionally, it suggests that estimating neural survival preoperatively is important for choosing the most appropriate electrode array type (perimodiolar vs. lateral wall) for optimal implant function. (wustl.edu)
  • Approximately 63 percent of patients who have received a VNS implant report up to a 50 percent reduction in the amount of seizures, a reduction in hospital admissions and a substantial improvement in quality of life. (sutterhealth.org)
  • When we don't know exactly where a patient's seizures are coming from, we surgically implant electrodes in and around the brain. (medlineplus.gov)
  • A pulse generator , which is a flat disc about 1.5 inches across that sends a tiny electrical impulse to a cuff electrode when it gets the signal from the breathing monitor. (hopkinsmedicine.org)
  • those wires are plugged into a computer, feeding the electrical signals generated by neurons firing near each electrode into the machine. (technologyreview.com)
  • All eight participants had electrodes implanted into the PMC for electrical stimulation. (scientificamerican.com)
  • We demonstrate that hippocampal slices can be imaged through transparent graphene electrodes by both confocal and two-photon microscopy without causing any light-induced artefacts in the electrical recordings. (nature.com)
  • Advances include epilepsy surgery in infants, the use of implanted depth electrodes for surgical mapping, intra-operative computer guidance systems, the use of 3D electrical dipole models and the use of new neuro-imaging systems for brain mapping and for identification of the epileptic zone. (ualberta.ca)
  • These results could suggest that ears able to take advantage of the proximal placement of electrodes are likely to have better speech recognition outcomes. (wustl.edu)
  • Applications for stimulating interfaces include sensory prosthetics (cochlear implants), for example, are the most successful variety of sensory prosthetics) and deep brain stimulation therapies, while recording interfaces can be used for research applications[11] and to record the activity of speech or motor centers directly from the brain. (wikipedia.org)
  • Temporal modulation sensitivity has been studied extensively for cochlear implant (CI) users due to its strong correlation to speech recognition outcomes. (wustl.edu)
  • The ears showing positive MDT-distance correlations, thus benefiting from electrodes being close to the neural elements, were those who performed better on the two speech recognition measures, i.e., speech reception thresholds (SRTs) and recognition of the AzBio sentences. (wustl.edu)
  • Alternatively, ears with good speech recognition outcomes may have good overall neural health, which is a precondition for close electrodes to produce spatially confined neural excitation patterns that facilitate modulation sensitivity. (wustl.edu)
  • Children with cochlear implants begin auditory rehabilitation (listening therapy) and speech and language therapy soon after surgery. (kidshealth.org)
  • Repeated testing of his hearing and speech perception with the cochlear implant showed no deterioration. (cdc.gov)
  • In paper V, sensory processing in primary somatosensory cortex during an episode of hyperalgesia was monitored using implanted neural interfaces in order to further evaluate the probe functionality and usefulness in neurophysiological research. (lu.se)
  • Children over 2 years old with cochlear implants also should get the pneumococcal polysaccharide vaccine (PPSV23) to help protect against meningitis. (kidshealth.org)
  • The clinical use of the new electrodes include application for symptomatic relief of chronic pain and movement disorders such as Parkinson's disease, improving control of prostheses in paralyzed patients and diagnostics in patients suffering from drug resistant epilepsy. (lu.se)
  • This review aimed to expose some clinical, microbiological and radiographic characteristics found in periodontal tissues and around dental implants. (bvsalud.org)
  • The use of dental implants to replace teeth is an important component of clinical Dentistry today. (bvsalud.org)
  • The biological and clinical successes demonstrated in prospective longitudinal studies have provided evidence of the appropriateness of the use of dental implants 1,2 . (bvsalud.org)
  • Taking into account these aforementioned factors, the objective of this study was to review the clinical, microbiological, and radiographic changes around implants. (bvsalud.org)
  • The loading time (e.g., early or delayed) does not seem to have any significant clinical impact on the marginal peri-implant bone or soft-tissue levels 9 . (bvsalud.org)
  • In a paper in the journal Advanced Healthcare Materials , the multi-institutional team used their "injectrodes" to stimulate the nervous systems of rats and pigs, with comparable results to existing implant technologies. (ieee.org)
  • These studies are typically conducted in people who have epilepsy because doctors implant electrodes in the brains of these research volunteers to monitor their brain activity prior to surgery. (scientificamerican.com)
  • It provides an easy area for a surgeon to hold and control the electrode, even into the facial recess. (advancedbionics.com)
  • 2014) found that a cochleostomy approach lead to electrodes in the scala vestibuli significantly more often, even when controlling for array design. (medel.pro)
  • However, surgical approach isn't the only significant factor in electrode array deviation. (medel.pro)
  • Friehs starts by implanting a four-millimeter-square array of 100 electrodes in this region, which is located in the brain's outermost layer, about halfway between the ear and the top of the skull. (technologyreview.com)
  • In those initial trials, the company will implant the electrode array, manufactured by Salt Lake City, UT-based Bionic Technologies, but the signal-processing hardware and power supply will remain outside of the body. (technologyreview.com)
  • At the start of 2020, he had a total of 14 electrodes implanted across his brain. (technologyreview.com)
  • O'Keefe had his Stentrode device implanted in spring 2020, thanks to Australia's relatively lax, risk-based regulation of medical devices. (insider.com)
  • By minimizing cochlear disruption, HiFocus electrodes offer an increased opportunity for better hearing outcomes. (advancedbionics.com)
  • Is Hearing With a Cochlear Implant Like Normal Hearing? (kidshealth.org)
  • Sound quality from a cochlear implant is different from that in normal hearing. (kidshealth.org)
  • Cochlear implants are considered for children with profound hearing loss who can be as young as 9 months old. (kidshealth.org)
  • Depending on a child's hearing, the doctor may recommend getting two cochlear implants, one for each ear. (kidshealth.org)
  • An advanced implant works with your audio processor to give you the best sound quality possible-whether you're talking to friends, enjoying your favourite music or just hearing the little sounds in life. (medel.com)
  • That's why you should think about which implant will give you the best hearing both now, and in the future. (medel.com)
  • MED-EL cochlear implants use advanced coding strategies, designed to give you the closest to natural hearing of any CI system. (medel.com)
  • This way, you can make the most of your cochlear implant, and experience the best hearing you possibly can. (medel.com)
  • Just because you are receiving your implant now, that doesn't mean that you won't benefit from future hearing technology. (medel.com)
  • You also need to choose an audio processor, which will work with your CONCERTO implant to give you great hearing. (medel.com)
  • A cochleostomy can lead to a higher likelihood of electrodes in the scala vestibuli. (medel.pro)
  • Here, we report a transparent, flexible neural electrode technology based on graphene, which enables simultaneous optical imaging and electrophysiological recording. (nature.com)
  • We investigated graphene, an emerging two-dimensional material, to build low noise, transparent and flexible neural electrodes. (nature.com)
  • Jens Schouenborg and his research group have been working for a long time on developing thinner and more flexible electrodes that can follow the brain's natural movements. (lu.se)
  • It was shown that thin, flexible electrodes with approximately the same density as brain tissue caused the least damage. (lu.se)
  • This was a breakthrough for flexible implants. (lu.se)
  • We succeeded in showing that super-thin flexible electrodes can be implanted in the brain without damaging it, and that kill-zones are practically non-existent around this type of implant. (lu.se)
  • "At the moment we are working on the nanostructuring of the super-thin, flexible electrodes", says Jens Schouenborg, somewhat cryptically. (lu.se)
  • The remaining challenge is to make the nanowire-based electrodes as flexible as those on a microscale. (lu.se)
  • An important aspect is to ensure positional stability of the implanted flexible electrodes for long periods of time, using highly innovative methods and techniques, as this is required for advanced analysis of neuronal network functions. (lu.se)
  • To address these challenges, we have for more than a decade systematically researched underlying mechanisms for these tissue reactions and developed new surgical methods, ultraflexible constructions and novel vehicles for enabling implantation of ultraflexible electrodes equipped with fragile nanostructures into soft tissue. (lu.se)
  • The focus is on developing truly biocompatible electrode constructions and implantation methods that cause minimal injury or irritation of the brain tissue, ensuring that physiological conditions are preserved. (lu.se)
  • This transparent electrode technology may pave the way for high spatio-temporal resolution electro-optic mapping of the dynamic neuronal activity. (nature.com)
  • Influence of probe flexibility and gelatin embedding on neuronal density and glial responses to brain implants. (lu.se)
  • We also put a lot of effort in developing software to be able to analyze the enormous amount of data acquired from implanted electrodes and for computer assisted interaction with neuronal networks. (lu.se)
  • In principle these systems are susceptible to the same tissue response that causes failure in implanted electrodes, but stimulating interfaces can overcome this problem by increasing signal strength. (wikipedia.org)
  • As we learn more and more about how to interface with the nervous system, we're not limited to what we've implanted through an invasive surgical procedure. (medicaldesignbriefs.com)
  • In recent years, the standard approach to cochlear implantation with a large incision has been challenged by successful implantation of cochlear implants in numerous patients with a much smaller incision and a less-invasive approach. (medscape.com)
  • It has three parts that are surgically implanted in the neck and chest, and a remote to control the device. (hopkinsmedicine.org)
  • Implanting such a device can involve cutting through muscle and nerves (and may require changing a battery every few years). (ieee.org)
  • When you feel symptoms, you turn on the device and place the electrodes on your chest to record the ECG. (medlineplus.gov)
  • But because of a new device implanted inside the blood vessels at the top of his head , he can harness his thoughts to propel a computer's actions: Click, zoom in, move the mouse right, move it left. (insider.com)
  • O'Keefe, who lives in Melbourne, Australia, is one of fewer than 40 people worldwide to have a functioning BCI device implanted into their skulls. (insider.com)
  • The most common complications associated with the standard approach to cochlear implantation include flap breakdown and electrode misplacement. (medscape.com)
  • It is ultimately this tissue response that causes electrodes to fail by encapsulating the electrode itself in a protective layer called a "glial scar," (see 2.2). (wikipedia.org)
  • However, this advance depended on microscopic electrodes implanted in the rats' heads. (livescience.com)
  • The HiRes Ultra implant family offers two electrode designs, the straight HiFocus™ SlimJ electrode and the precurved HiFocus™ Mid-Scala electrode, to offer the surgeon a choice based on their practice preferences and the recipient's anatomy. (advancedbionics.com)
  • The HiFocus SlimJ or HiFocus Mid-Scala electrode provide the surgeon with maximum surgical flexibility based upon surgical preference while maintaining patient performance. (advancedbionics.com)
  • The surgeon places the VNS pulse generator under the skin of the chest in a surgically created pocket and tunnels the electrode under the skin from the neck incision. (sutterhealth.org)
  • Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes always better? (wustl.edu)
  • We tested 13 ears for the effect of distance on modulation sensitivity, specifically targeting the question of whether electrodes closer to the modiolus are universally beneficial. (wustl.edu)
  • Dive into the research topics of 'Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes always better? (wustl.edu)
  • The distance measures were correlated with slopes of spatial tuning curves measured on selected electrodes to investigate if electrode position accounts, at least in part, for the width of neural excitation. (wustl.edu)
  • In accordance with previous findings, electrode position explained 24% of the variance in slopes of the spatial tuning curves. (wustl.edu)
  • To date, only one company has conducted human tests of a brain-recording implant with the aim of helping restore function in paralyzed patients: Atlanta, GA-based Neural Signals. (technologyreview.com)
  • External electrodes, picking up myoelectrical (EMG) signals, can also be utilized, but again the numbers of signals are limited. (hindawi.com)
  • Despite the anatomical differences between the periodontium and the tissues around implants, several studies have indicated some similarities, such as the production of inflammatory mediators and active microbiota. (bvsalud.org)
  • The problem with most of the electrodes used today is that they are stiff and often quite rough, which means they irritate the brain tissue when the brain moves, which it does more or less the whole time, such as when we breathe or move our head. (lu.se)
  • Local delivery of minocycline‑loaded PLGA nanoparticles from gelatin‑coated neural implants attenuates acute brain tissue responses in mice. (lu.se)
  • The experimental group had stimulating electrodes implanted into the subthalamic nuclei (STN) of their brain in addition to treatment with L-dopa. (scienceblogs.com)
  • Dicho uso tenía influencias de la fisiología -- especialmente de la neurofisiología -- y de estudios en Psicología Experimental. (bvsalud.org)
  • In experimental studies, periimplantitis is characterized by the inflammation of the soft tissues, bleeding, and suppuration, as well as rapid bone loss around dental implants that are in function. (bvsalud.org)
  • This confirms previous studies of experimental peri-implantitis, which were conducted on various implants with different designs 23,27 . (bvsalud.org)