Use of electric potential or currents to elicit biological responses.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
Electronic hearing devices typically used for patients with normal outer and middle ear function, but defective inner ear function. In the COCHLEA, the hair cells (HAIR CELLS, VESTIBULAR) may be absent or damaged but there are residual nerve fibers. The device electrically stimulates the COCHLEAR NERVE to create sound sensation.
Order of mammals whose members are adapted for flight. It includes bats, flying foxes, and fruit bats.
The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing.
Artificial device such as an externally-worn camera attached to a stimulator on the RETINA, OPTIC NERVE, or VISUAL CORTEX, intended to restore or amplify vision.
Use of sound to elicit a response in the nervous system.
NEURAL PATHWAYS and connections within the CENTRAL NERVOUS SYSTEM, beginning at the hair cells of the ORGAN OF CORTI, continuing along the eighth cranial nerve, and terminating at the AUDITORY CORTEX.
In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672)
Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.
The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY.
A general term for the complete loss of the ability to hear from both ears.
The posterior pair of the quadrigeminal bodies which contain centers for auditory function.
A dimension of auditory sensation varying with cycles per second of the sound stimulus.
The audibility limit of discriminating sound intensity and pitch.
The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
The science pertaining to the interrelationship of psychologic phenomena and the individual's response to the physical properties of sound.
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Elements of limited time intervals, contributing to particular results or situations.
Fields representing the joint interplay of electric and magnetic forces.
The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
An order of neotropical electric fish found chiefly in the waters of South America. They continually emit weak electric discharges, which they use in object location and communication. A most popular species of research interest is the electric eel, ELECTROPHORUS electricus.
Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.
The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.
Act of eliciting a response from a person or organism through physical contact.
A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.
An arrangement of wires distributing electricity.
The ability of a substrate to allow the passage of ELECTRONS.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A technique in which electric pulses of intensity in kilovolts per centimeter and of microsecond-to-millisecond duration cause a temporary loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
Devices that control the supply of electric current for running electrical equipment.
A genus of the Torpedinidae family consisting of several species. Members of this family have powerful electric organs and are commonly called electric rays.
The resistance to the flow of either alternating or direct electrical current.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Burns produced by contact with electric current or from a sudden discharge of electricity.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
The rate dynamics in chemical or physical systems.
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.
The use of specifically placed small electrodes to deliver electrical impulses across the SKIN to relieve PAIN. It is used less frequently to produce ANESTHESIA.
A genus of fish, in the family GYMNOTIFORMES, capable of producing an electric shock that immobilizes fish and other prey. The species Electrophorus electricus is also known as the electric eel, though it is not a true eel.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Established cell cultures that have the potential to propagate indefinitely.
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
Communication between animals involving the giving off by one individual of some chemical or physical signal, that, on being received by another, influences its behavior.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
Electrodes with an extremely small tip, used in a voltage clamp or other apparatus to stimulate or record bioelectric potentials of single cells intracellularly or extracellularly. (Dorland, 28th ed)
The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The property of nonisotropic media, such as crystals, whereby a single incident beam of light traverses the medium as two beams, each plane-polarized, the planes being at right angles to each other. (Cline et al., Dictionary of Visual Science, 4th ed)
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
Units that convert some other form of energy into electrical energy.
Contractile tissue that produces movement in animals.
The function of opposing or restraining the excitation of neurons or their target excitable cells.
The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Induction of a stress reaction in experimental subjects by means of an electrical shock; applies to either convulsive or non-convulsive states.
Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Lens-shaped structure on the inner aspect of the INTERNAL CAPSULE. The SUBTHALAMIC NUCLEUS and pathways traversing this region are concerned with the integration of somatic motor function.
Characteristics of ELECTRICITY and magnetism such as charged particles and the properties and behavior of charged particles, and other phenomena related to or associated with electromagnetism.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
The time from the onset of a stimulus until a response is observed.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Neurons which activate MUSCLE CELLS.
Stimulation of the brain, which is self-administered. The stimulation may result in negative or positive reinforcement.
Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors.
The process in which specialized SENSORY RECEPTOR CELLS transduce peripheral stimuli (physical or chemical) into NERVE IMPULSES which are then transmitted to the various sensory centers in the CENTRAL NERVOUS SYSTEM.
The common name for all members of the Rajidae family. Skates and rays are members of the same order (Rajiformes). Skates have weak electric organs.
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Neural tracts connecting one part of the nervous system with another.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
The physical characteristics and processes of biological systems.
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
Computer-based representation of physical systems and phenomena such as chemical processes.

Inhibitory innervation of cat sphincter of Oddi. (1/19053)

1 Electrical stimulation with trains of 0.1-0.2 ms pulses of the cat isolated sphincter of Oddi inhibited the spontaneous contractile activity and lowered base-line tension considerably. A contraction usually followed the period of stimulation. 2 These inhibitory effects were prevented by tetrodotoxin 0.1-0.5 mug/ml but were not reduced by hexamethonilm, morphine, or blockade of alpha- or beta-adrenoreceptors of cholinoceptors with phenoxy-benzamine propranolol or atropine, respectively. 3 Adenosine-5'-triphosphate (ATP) and adenosine-5'-diphosphate (ADP) inhibited the spontaneous sphincter activity and caused relaxation thus mimicking the effects of the C-terminal octapeptide of cholecystokinin (C8-CCK), isoprenaline and prostaglandin E1 and E2. 4 ATP alone (greater than 100 mug/ml) or ATP (greater than 10 mug/ml) plus dipyridamole (1 mug/ml), relaxed the sphincter to the same degrees as did the field stimulation. 5 In sphincter maximally contracted by acetylcholine, the effect of stimulation was more marked than that recorded in uncontracted preparations. 6 The present findings suggest that the sphincter of Oddi receives inhibitory nerves that are neither cholinergic nor adrenergic.  (+info)

Further evidence that prostaglandins inhibit the release of noradrenaline from adrenergic nerve terminals by restriction of availability of calcium. (2/19053)

1 Guinea-pig vasa deferentia were continuously superfused after labelling the transmitter stores with [3H](-)-noradrenaline. Release of [3H]-(-)-noradrenaline was induced by transmural nerve stimulation. 2 Prostglandin E2 (14 nM) drastically reduced the release of [3H]-(-)-noradrenaline, while tetraethylammonium (2 mM), rubidium (6 mM), phenoxybenzamine (3 muM) each in the presence or absence of Uptake 1 or 2 blockade, and prolonged pulse duration (from 0.5 to 2.0 ms) all significantly increased the release of [3H]-(-)-noradrenaline per nerve impulse. 3 The inhibitory effect of prostaglandin E2 on evoked release of [3H]-(-)-noradrenaline was significantly reduced by tetraethylammonium, rubidium and prolonged pulse duration, whilst it was actually enhanced by phenoxybenzamine. This indicates that increased release of noradrenaline per nerve impulse does not per se counteract the inhibitory effect of prostaglandin E2. 4 It is concluded that tetraethylammonium, rubidium and prolonged pulse duration counteracted the inhibitory effect of prostaglandin E2 on T3H]-(-)-noradrenaline release by promoting calcium influx during the nerve action potential. The results are consistent with, and add more weight to the view that prostaglandins inhibit the release of noradrenaline by restriction of calcium availability.  (+info)

Automatic activity in depolarized guinea pig ventricular myocardium. Characteristics and mechanisms. (3/19053)

Membrane potential was changed uniformly in segments, 0.7-1.0 mm long, of guinea pig papillary muscles excised from the right ventricle by using extracellular polarizing current pulses applied across two electrically insulated cf preparations superfused with Tyrode's solution at maximum diastolic membrane potentials ranging from-35.2+/-7.5 (threshold) to +4.0+/-9.2 mV. The average maximum dV/dt of RAD ranged from 17.1 to 18.0 V/sec within a membrane potential range of -40 to +20 mV. Raising extracellular Ca2+ concentration [Ca2+]0 from 1.8 to 6.8 mM, or application of isoproterenol (10(-6)g/ml) enhanced the rate of RAD, but lowering [Ca2+]0 to 0.4 mM or exposure to MnCl2 (6 mM) abolished RAD. RAD were enhanced by lowering extracellular K+ concentration [K+]0 from 5.4 to 1.5 mM. RAD were suppressed in 40% of fibers by raising [K+]0 to 15.4 mM, and in all fibers by raising [K+]0 to 40.4 mM. This suppression was due to increased [K+]0 and not to K-induced depolarization because it persisted when membrane potential was held by means of a conditioning hyperpolarizing puled gradually after maximum repolarization. These observations suggest that the development of RAD in depolarized myocardium is associated with a time-dependent decrease in outward current (probably K current) and with increase in the background inward current, presumably flowing through the slow cha-nel carrying Ca or Na ions, or both.  (+info)

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (4/19053)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

The effect of cardiac contraction on collateral resistance in the canine heart. (5/19053)

We determined whether the coronary collateral vessels develop an increased resistance to blood flow during systole as does the cognate vascular bed. Collateral resistance was estimated by measuring retrograde flow rate from a distal branch of the left anterior descending coronary artery while the main left coronary artery was perfused at a constant pressure. Retrograde flow rate was measured before and during vagal arrest. We found that in 10 dogs the prolonged diastole experienced when the heart was stopped caused no significant change in the retrograde flow rate, which indicated that systole has little effect on the collateral resistance. However, when left ventricular end-diastolic pressure was altered by changing afterload or contractility, a direct relationship between end-diastolic pressure and collateral resistance was noted.  (+info)

Effect of electrotonic potentials on pacemaker activity of canine Purkinje fibers in relation to parasystole. (6/19053)

Isolated false tendons excised form dog hearts were mounted in a three-chamber tissue bath. Isotonic sucrose solution was perfused in the central chamber to provide a region of depressed conductivity between the fiber segments in chambers 1 and 3, which were perfused with Tyrode's solution. The electrotonic influence of spontaneous or driven responses evoked in chamber 3 during the first half of the spontaneous cycle of a chamber 1 peacemaker delayed the next spontaneous discharge. This effect changed to acceleration when the chamber 3 segment fired during the second half of the spontaneous cycle. We found that subthreshold depolarizing current pulses 50-300 msec applied across the sucrose gap caused similar degrees of delay or acceleration. Furthermore, hyperpolarizing currents caused the reverse pattern. The results indicate that the discharge pattern of a parasystolic focus may be altered by the electrotonic influence of activity in the surrounding tissue. The significance of these findings is considered in relation to the mechanism of production of parasystolic rhythms.  (+info)

Evaluation of the force-frequency relationship as a descriptor of the inotropic state of canine left ventricular myocardium. (7/19053)

The short-term force-frequency characteristics of canine left ventricular myocardium were examined in both isolated and intact preparations by briefly pertubing the frequency of contraction with early extrasystoles. The maximum rate of rise of isometric tension (Fmas) of the isolated trabeculae carneae was potentiated by the introduction of extrasystoles. The ratio of Fmas of potentiated to control beats (force-frequency ratio) was not altered significantly by a change in muscle length. However, exposure of the trabeculae to isoproterenol (10(-7)M) significantly changed the force-frequency ratio obtained in response to a constant frequency perturbation. Similar experiments were performed on chronically instrumented conscious dogs. Left ventricular minor axis diameter was measured with implanted pulse-transit ultrasonic dimension transducers, and intracavitary pressure was measured with a high fidelity micromanometer. Atrial pacing was performed so that the end-diastolic diameters of the beats preceding and following the extrasystole could be made identical. Large increases in the maximum rate of rise of pressure (Pmas) were seen in the contraction after the extrasystole. The ratio of Pmax of the potentiated beat to that of the control beat was not changed by a 9% increase in the end-diastolic diameter, produced by saline infusion. Conversely, isoproterenol significantly altered this relationship in the same manner as in the isolated muscle. Thus, either in vitro or in situ, left ventricular myocardium exhibits large functional changes in response to brief perturbations in rate. The isoproterenol and length data indicate that the force-frequency ratio reflects frequency-dependent changes in the inotropic state, independent of changes in length.  (+info)

Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection. (8/19053)

Excitatory synaptic transmission between pyramidal cells and fast-spiking (FS) interneurons of layer V of the motor cortex was investigated in acute slices by using paired recordings at 30 degrees C combined with morphological analysis. The presynaptic and postsynaptic properties at these identified central synapses were compared between 3- and 5-week-old rats. At these two postnatal developmental stages, unitary EPSCs were mediated by the activation of AMPA receptors with fast kinetics at a holding potential of -72 mV. The amplitude distribution analysis of the EPSCs indicates that, at both stages, pyramidal-FS connections consisted of multiple functional release sites. The apparent quantal size obtained by decreasing the external calcium ([Ca2+]e) varied from 11 to 29 pA near resting membrane potential. In young rats, pairs of presynaptic action potentials elicited unitary synaptic responses that displayed paired-pulse depression at all tested frequencies. In older animals, inputs from different pyramidal cells onto the same FS interneuron had different paired-pulse response characteristics and, at most of these connections, a switch from depression to facilitation occurred when decreasing the rate of presynaptic stimulation. The balance between facilitation and depression endows pyramidal-FS connections from 5-week-old animals with wide integrative capabilities and confers unique functional properties to each synapse.  (+info)

TY - JOUR. T1 - Twitch potentiation after voluntary contraction and neuromuscular electrical stimulation at various frequencies in human quadriceps femoris. AU - Miyamoto, Naokazu. AU - Fukutani, Atsuki. AU - Yanai, Toshimasa. AU - Kawakami, Yasuo. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Introduction: In this study we aimed to compare the extent of twitch potentiation (TP) after voluntary contraction and percutaneous electrical stimulation of muscles (neuromuscular electrical stimulation: NMES) with various stimulation frequencies at equivalent target levels. Methods: Isometric knee extensions of 10 s were performed at a 40% maximal voluntary contraction level by voluntary or NMES conditioning contractions at 20, 40, and 80 H Z of the quadriceps femoris muscle. Twitch responses were elicited by stimulating the femoral nerve transcutaneously at supramaximal intensity. Results: NMES at 80 HZ induced significantly less TP (128.7 ± 17.1%) than voluntary contraction (156.2 ± 23.1%), whereas no ...
The spatial extent of transcranial magnetic stimulation (TMS) is of paramount interest for all studies employing this method. It is generally assumed that the induced electric field is the crucial parameter to determine which cortical regions are excited. While it is difficult to directly measure the electric field, one usually relies on computational models to estimate the electric field distribution. Direct electrical stimulation (DES) is a local brain stimulation method generally considered the gold standard to map structure-function relationships in the brain. Its application is typically limited to patients undergoing brain surgery. In this study we compare the computationally predicted stimulation area in TMS with the DES area in six patients with tumors near precentral regions. We combine a motor evoked potential (MEP) mapping experiment for both TMS and DES with realistic individual finite element method (FEM) simulations of the electric field distribution during TMS and DES. On average, ...
Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo. med./bio. ...
Birba A, Hesse E, Sedeño L, Mikulan EP, García MDC, Ávalos J, Adolfi F, Legaz A, Bekinschtein TA, Zimerman M, Parra M, García AM, Ibáñez A. Enhanced Working Memory Binding by Direct Electrical Stimulation of the Parietal Cortex. Front Aging Neurosci. 2017 Jun 8;9:178. doi: 10.3389/fnagi.2017.00178 La memoria de trabajo de integración (WMB) es un marcador preclínico de la enfermedad de Alzheimer (EA) que depende de regiones posteriores del cerebro. La estimulación de la corteza parietal posterior (PPC) podría ser un target terapéutico en la EA. En este estudio, encontramos que la estimulación eléctrica y directa intracraneal de regiones específicas de la PPC durante la WMB induce una mejora selectiva en el desempeño.
Although initial studies suggested that the MEP in the rat arises from activation of the spinal pyramidal pathway, subsequent studies have raised doubts concerning the pyramidal origin of the MEP and have proposed that the spread of stimulation current in some of these studies resulted in activation of the extrapyramidal system. [18-24] Ryder and colleagues [24] showed that monopolar stimulation of the sensorimotor cortex activates the extrapyramidal and pyramidal tracts, and bipolar stimulation restricted to the motor cortex using low stimulus current activates only the pyramidal tract. They concluded that early and late latency spinal-evoked responses were considered to be induced by activation of extrapyramidal and pyramidal tracts, respectively. Although we used bipolar stimulation of the motor cortex in the present study, stimulus current was higher than that reported by Ryder and colleagues. [24] Both extrapyramidal and pyramidal tracts must be activated in the present study. However, it ...
Autor: Borchers, S et al.; Genre: Zeitschriftenartikel; Im Druck veröffentlicht: 2012-01; Titel: Direct electrical stimulation of human cortex: the gold standard for mapping brain functions?
A system for providing medical electrical stimulation, the system features a pulse generator, the pulse generator generating electrical stimulation pulses of a first amplitude and a second amplitude, first and second elongated leads coupled to the pulse generator, a zener diode which directs electrical stimulation pulses of a first amplitude to the first lead and directs electrical stimulation pulses of a second amplitude to the first lead and the second lead, the means for directing electrical stimulation pulses coupled to the pulse generator. In the preferred embodiment the diode is electrically coupled to one of the leads such that electrical stimulation of a first amplitude is not passed through the diode while electrical stimulation of a second amplitude is passed through the diode. Overall the adaptor permits a single channel of stimulation to be split and provided to two areas of the heart merely be adjusting the amplitude of the stimulation pulses.
Cortical stimulation mapping (CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function. Cortical stimulation mapping is used for a number of clinical and therapeutic applications, and remains the preferred method for the pre-surgical mapping of the motor cortex and language areas to prevent unnecessary functional damage. There are also some clinical applications for cortical stimulation mapping, such as the treatment of epilepsy. The history of cortical stimulation mapping dates back to the late 19th century. Neurologists David Ferrier and Victor Horsley were some of the first to utilize this technique. Ferrier and Horsley employed CSM to further grasp the structure and function of the ...
TY - JOUR. T1 - Spatial heterogeneity of transmembrane potential responses of single guinea-pig cardiac cells during electric field stimulation. AU - Sharma, Vinod. AU - Tung, Leslie. PY - 2002/7/15. Y1 - 2002/7/15. N2 - Changes in transmembrane voltage (Vm) of cardiac cells during electric field stimulation have a complex spatial- and time-dependent behaviour that differs significantly from electrical stimulation of space-clamped membranes by current pulses. A multisite optical mapping system was used to obtain 17 or 25 μm resolution maps of Vm along the long axis of guinea-pig ventricular cells (n = 57) stained with voltage-sensitive dye (di-8-ANEPPS) and stimulated longitudinally with uniform electric field (2, 5 or 10 ms, 3-62 V cm-1) pulses (n = 201). The initial polarizations of Vm responses (Vmr) varied linearly along the cell length and reversed symmetrically upon field reversal. The remainder of the Vm responses had parallel time courses among the recording sites, revealing a common ...
The present preliminary report describes the electrophysiological response of the cochlea during long-term stimulation. The data indicate that electrical stimulation at a rate of 1000 pulses per second does not appear to adversely affect the implanted cochlea ...
Direct electrical stimulation of the brain has emerged as a powerful treatment for multiple neurological diseases, and as a potential technique to enhance human cognition. Despite its application in a range of brain disorders, it remains unclear how stimulation of discrete brain areas affects memory performance and the underlying electrophysiological activities. Here, we investigated the effect of direct electrical stimulation in four brain regions known to support declarative memory: hippocampus (HP), parahippocampal region (PH) neocortex, prefrontal cortex (PF), and lateral temporal cortex (TC). Intracranial EEG recordings with stimulation were collected from 22 patients during performance of verbal memory tasks. We found that high γ (62-118 Hz) activity induced by word presentation was modulated by electrical stimulation. This modulatory effect was greatest for trials with poor memory encoding. The high γ modulation correlated with the behavioral effect of stimulation in a given brain region: it
NEW FINDINGS. What is the central question of this study? How does peripheral nerve stimulation (PNS) compare with neuromuscular electrical stimulation (NMES) used clinically to reduce muscle atrophy? What is the main finding and its importance? NMES resulted in progressive increases in M-wave duration and delay of muscle relaxation throughout a single stimulation protocol, findings not observed with PNS. This suggests PNS recruits from a wider pool of muscle fibres/motor units, providing a more favourable alternative to NMES for rehabilitation intervention.. ABSTRACT. Neuromuscular electrical stimulation (NMES) is increasingly viewed as a central tenet to minimise muscle loss during periods of disuse/illness - typically applied directly over a muscle belly. Peripheral nerve stimulation (PNS) is afforded less attention, despite providing a more global contractile stimulus to muscles. We investigated NMES versus PNS in relation to performance fatigability and peripheral contributions to voluntary ...
It is the function of a pacemaker to provide electrical stimulation pulses to the appropriate chamber(s) of the heart (atria or ventricles) in the event that the heart is unable to beat of its own (i.e. in the event that either the sinoatrial node fails to generate its own natural stimulation pulses at an appropriate sinus rate, or in the event such natural stimulation pulses do not effectively propagate to the appropriate cardiac tissue). Most modern pacemakers accomplish this function by operating in a demand mode where stimulation pulses from the pacemaker are provided to the heart only when the heart is not beating of its own, as sensed by monitoring the appropriate chamber of the heart for the occurrence of a P-wave or R-wave. If a P-wave or a R-wave is not sensed within a prescribed period of time (which period of time is usually referred to as the escape interval), then a stimulation pulse is generated at the end of this prescribed period of time and delivered to the appropriate heart ...
TY - JOUR. T1 - Corticospinal potentials after electrical and magnetic stimulation in man.. AU - Berardelli, A.. AU - Inghilleri, M.. AU - Cruccu, G.. AU - Manfredi, M.. PY - 1991. Y1 - 1991. N2 - The present report deals with our study of the descending volley evoked by both electrical and magnetic transcranial stimulation in man. We discuss the differences of these two techniques specifically as regards the latency and amplitude of evoked potentials. In both cases, electrodes were placed either in the epidural space or directly on the spinal cord. Following electrical stimulation, the descending volley consisted of an early wave which appeared at low stimulation intensity and increased in amplitude and decreased in latency when the strength of the stimulus was increased. At high stimulation intensities the early wave was followed by later waves which travel at the same speed as the initial wave. By delivering paired cortical stimuli, the early wave evoked by the test stimuli is present at ...
TY - JOUR. T1 - Inhibition of mitochondrial Ca2+ uptake affects phasic release from motor terminals differently depending on external [Ca2+]. AU - Talbot, Janet D.. AU - David, Gavriel. AU - Barrett, Ellen. PY - 2003/7/1. Y1 - 2003/7/1. N2 - We investigated how inhibition of mitochondrial Ca2+ uptake affects stimulation-induced increases in cytosolic [Ca2+] and phasic and asynchronous transmitter release in lizard motor terminals in 2 and 0.5 mM bath [Ca2+], Lowering bath [Ca2+] reduced the rate of rise, but not the final amplitude, of the increase in mitochondrial [Ca2+] during 50-Hz stimulation. The amplitude of the stimulation-induced increase in cytosolic [Ca2+] was reduced in low-bath [Ca2+] and increased when mitochondrial Ca2+ uptake was inhibited by depolarizing mitochondria. In 2 mM Ca2+, end-plate potentials (epps) depressed by 53% after 10 s of 50-Hz stimulation, and this depression increased to 80% after mitochondrial depolarization. In contrast, in 0.5 mM Ca2+ the same stimulation ...
Electrical stimulation of the central nervous system albeit an unnatural way, has been found to be an effective way of causing neuronal excitation. Retinal prosthesis is an example of such a neuroprosthesis that strives to provide vision to people suffering from Retinitis Pigmentosa and Age-related Macular Degeneration. In these diseases, the photoreceptors in the retina undergo a progressive degeneration leaving the remaining retinal neurons relatively intact. It is by electrically stimulating these retinal neurons that a retinal prosthesis aims to elicit visual percepts.; In addition to providing effective stimulation, such a device has to do so in a manner that is safe for both the device and surrounding biological environment. Numerous studies have been performed to assess the safety limits of electrical stimulation of neurons. However, majority of these studies have been performed in structures other than the retina. The few safety studies performed in the retina have looked at the effect ...
Local electrical stimulations of the ventral prelimbic cortex ameliorates depressive-like behavioral traits in a genetic rat model for major depression Conference Paper ...
Abstract: : Purpose: Nitric oxide is produced by many retinal neurons, however its ability to modulate synaptic activity in the inner retina is poorly understood. I examined how nitric oxide modulates the excitatory and inhibitory synaptic inputs to ganglion cells evoked by light and by focal electrical stimulation. Methods: I recorded postsynaptic currents from ganglion cells using whole-cell patch clamp techniques in retinal slices prepared under infrared illumination. Responses were elicited by a green LED (1 sec duration) and by brief focal electrical stimulation (zap; 1 msec; .1 - 1.5 µA) of the outer-plexiform layer. Strychnine (10 µM) was used to isolate the GABAergic inputs. Results: Nitric oxide has been shown to affect photoreceptor calcium currents, so I compared responses elicited by illumination with those elicited by the zap, which directly depolarizes bipolar cells to activate inputs to the inner plexiform layer. Application of the nitric oxide donor, NONOate (100 µM) rapidly ...
We tested six stimulation paradigms that consisted of either uniform trains of single pulses or patterned stimulation trains applied at variable low frequencies and either low- or high-intensity current. Low-intensity, prolonged stimulation at 1-5 Hz did not cause any changes but at 10 Hz reliably elicited homosynaptic depression, an effect that dissipated within 3 hr in every case (Figs. 1,2 A, 3 A). High-intensity, prolonged stimulation at 1 Hz still had no impact, but at 5 Hz caused a depression encompassing both pathways and recovering within 1-3 hr (Fig. 3 B). High-intensity current at stimulation of 10 Hz led to a complete and apparently permanent loss of the homosynaptic response, an effect that seemed pathological and of uncertain relevance to normal synaptic operations. Overall, the impact of uniform trains of low-frequency pulses was more pronounced the smaller interpulse intervals and the higher the current intensity. However, in no case did the depression last much longer than 3 ...
Thanks to the IGIA Electro Pulse Stimulation Massager you can get effective pain relief without medicine!This travel-size battery-powered massager is convenient not only to aid in body pain conditions but also in slimming down. This product is great for relieving tiredness, relaxing muscles, improving blood circulation
Methods and apparatus for testing of the efficacy of therapeutic stimulation of pelvic nerves or musculature to alleviate one of incontinence or sexual dysfunction are disclosed. A therapy delivery device is operable in a therapy delivery mode and a test mode and an evoked response detector is employed in the test mode to detect the evoked response to applied test stimuli. The test stimuli parameters of the test stimulation regimen are adjusted prior to delivery of each test stimulation regimen, and the evoked responses to the applied test stimulation regimens are compared to ascertain an optimal test stimulation regimen. The therapy stimulation regimen parameters are selected as a function of the test electrical stimulation parameters causing the optimal evoked response.
During initial acquisition sessions the frequency was held constant (156 Hz) and the intensity was adjusted by the experimenter to determine the lowest intensity that maintained high rates of responding (more than 40 responses/min). Once responding was established, frequency-response curves were generated. These 2-h sessions consisted of six 10-min components, which were further broken down into ten 1-min trials. Each 60-s trial consisted of a 5-s timeout, then a 5-s period during which five noncontingent stimulations were delivered, and finally a 50-s period in which lever presses resulted in stimulation and were recorded. During these sessions the intensity remained the same (unique to each animal) and 10 frequencies (156-45 Hz, 0.06 log increments) corresponding to each trial were presented in descending order. A 1-h timeout period between the third and fourth components permitted drug injections during test sessions. During test sessions when fentanyl was administered, the timeout period was ...
A computer stimulated the prefrontal cortex exactly when braking was needed. This was done using electrodes implanted directly on the brain surface.. When the test was repeated with stimulation of a brain region outside the prefrontal cortex, there was no effect on behavior, showing the effect to be specific to the prefrontal braking system.. This was a double-blind study, meaning that participants and scientists did not know when or where the charges were being administered.. The method of electrical stimulation was novel in that it apparently enhanced prefrontal function, whereas other human brain stimulation studies mostly disrupt normal brain activity. This is the first published human study to enhance prefrontal lobe function using direct electrical stimulation, the researchers report.. The study involved four volunteers with epilepsy who agreed to participate while being monitored for seizures at the Mischer Neuroscience Institute at Memorial Hermann-Texas Medical Center (TMC). Stimulation ...
In general, the disclosure describes implantable pulse generators (IPGs) adapted to deliver stimulation to refractory myocardial tissue. An IPG nominally delivers one to six monophasic stimulation pulses. Because monophasic stimulation tends to accumulate polarization, a programmable blanking period of between about 20 milliseconds (ms) and about 300 ms is implemented (subsequent to delivery of the last pulse in a RPS pulse train) to allow recovery from polarization. The stimulation pulse width is about 0.03 ms to about 1.6 ms and voltage amplitude of 0.5 volts to 8 volts at about 50 Hz. The amplitude of electrical current of the stimulation pulses is less than or equal to approximately 50 milliamps. The pulses are delivered to multiple sites within a cardiac chamber and device performance and/or diagnostic information can be stored within a memory structure and reviewed to confirm delivery of a desired therapy regimen.
Vital Tones Muscle Stimulation Upper Body is an exclusive brainwave sound therapy for stimulating nerves and muscles of the upper body. Vital Tones stimulates nerves and muscles naturally through the specific parts of the motor cortex and the cerebellum. Vital Tones Muscle Stimulation can be used for the following: - Relaxation of muscle spasms; - Prevention or retardation of disuse. atrophy; - Increasing local blood circulation; - Muscle re-education; - Maintaining or increasing range of. motion. Vital Tones Muscle Stimulation Upper Body Pro consists of 7 different sessions. Session 1 and 2 is 12 minutes and the others 10 minutes long. Vital Tones Muscle Stimulation Upper Body trial version consists of only one session.
Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.
When surgery and medication dont help people with epilepsy, electrical stimulation of the brain has been a treatment of last resort. Unfortunately, typical approaches, such as vagal nerve stimulation or responsive nerve stimulation, rarely stop seizures altogether. But a new Mayo Clinic study in JAMA Neurology shows that seizures were suppressed in patients treated with…
Systems of and methods for stimulation of neurological tissue that may generate stimulation trains with temporal patterns of stimulation is shown and disclosed herein. The temporal patterns of stimulation may include intervals between electrical pulses (the inter-pulse intervals) that change or vary over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention may provide a lower average frequency.
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A study of activity recorded with intracellular micropipettes was undertaken in the caudal abdominal ganglion of the crayfish in order to gain information about central fiber to fiber synaptic mechanisms. This synaptic system has well developed integrative properties. Excitatory post-synaptic potentials can be graded, and synaptic potentials from different inputs can sum to initiate spike discharge. In most impaled units, the spike discharge fails to destroy the synaptic potential, thereby allowing sustained depolarization and multiple spike discharge following single pulse stimulation to an afferent input. Some units had characteristics which suggest a graded threshold for spike generation along the post-synaptic fiber membrane. Other impaled units responded to afferent stimulation with spike discharges of two distinct amplitudes. The smaller or abortive spikes in such units may represent non-invading activity in branches of the post-synaptic axon. On a few occasions one afferent input was ...
For each band of gaba synapses, this function makes a file with the // stimulation train and shifts the activation time (by temporal_offset) // written by Yiota Poirazi, July 2001, [email protected] double iary[1000] objref vary[1000], s_file, stimtmp, rpid stimtmp = new Vector() strdef shiftsyn_filename, syscmd, estr proc gaba_shift() { local synapses, temporal_offset, hertz, gmax_default, PID, lo, hi synapses = $1 // number of synapses in the band tstop = $2 // stimulation end time dt = $3 hertz = $4 // stimulation train frequency synch = $5 // synchronous or a synchronous stimulation of synapses perio = $6 // periodic or not periodic stimulation PID = $7 PID = abs(PID) // only positive random seeds used for spike train generation temporal_offset = $8 // shift stimulation time by temporal_offset // Make the desired activation pattern file and // Set GABA pointers to activation pattern sprint(shiftsyn_filename,gaba_shiftsyn-%d-%.2f-%.2f-%.2f-%.2f-%.2f-%d-%.2f,\ ...
TY - JOUR. T1 - Low-frequency stimulation induces stable transitions in stereotypical activity in cortical networks. AU - Vajda, I.. AU - van Pelt, J.. AU - Wolters, P.. AU - Chiappalone, M. AU - Martinoia, S. AU - van Someren, E.J.W.. AU - van Ooyen, A.. PY - 2008. Y1 - 2008. N2 - Reverberating spontaneous synchronized brain activity is believed to play an important role in neural information processing. Whether and how external stimuli can influence this spontaneous activity is poorly understood. Because periodic synchronized network activity is also prominent in in vitro neuronal cultures, we used cortical cultures grown on multielectrode arrays to examine how spontaneous activity is affected by external stimuli. Spontaneous network activity before and after low-frequency electrical stimulation was quantified in several ways. Our results show that the initially stable pattern of stereotypical spontaneous activity was transformed into another activity pattern that remained stable for at least ...
The Electric Eric provides both vibration and electrical stimulation at the same time and it DOES NOT require a nerve stimulator kit so no cables or added devices needed. Features two vibration motors: one in the tip and in the shaft with 8 different vibration programs and 5 different intensity levels along with 5 electrical stimulation programs with 10 different levels of intensity.
We induced atrioventricular dissociation and initiated ventricular pacing in intact dogs and isolated cat hearts. Left ventricular pressure, its time derivative (dP/t), and action potentials were recorded. When a test pulse was introduced at varying intervals after a period of steady pacing, an optimum contractile response was obtained at an average interval of 720 msec. A similar optimum interval was obtained after pacing at various frequencies and after paired pulse stimulation but was shortened to 560 msec after infusion of epinephrine. The magnitude of the optimum contractile response increased with an increase in the frequency of prior pacing which was accompanied by an increase in the time the cell membrane was depolarized. The optimum contractile response following paired pulse stimulation was greater than that following regular pacing, with the same number of stimuli per minute and the same time of membrane depolarization. The results are explicable in terms of intracellular calcium ion ...
Electrical Stimulation: How Does it Work and Why You May Not Need It. Electrical stimulation is a wonderful tool that physical therapists can use on a regular basis. There are different types of electrical stimulation units. These different types of units create different types of waveforms are and are used for very different reasons. Some waves help to reduce pain by stimulating certain parts of nerves that can send painful signals to the brain. Others can cause muscle contractions which can help to strength muscles. How does it work? Often patients are curious as to how electrical stimulation works. The specific wavelengths, frequencies, ramp up times and other technical aspects can be a bit overwhelming. These things are important to know if you want to get the most out of your experience with electrical stimulation. However, the basic concept of electrical stimulation is pretty simple.. Electricity is the language of our nervous system. All of our nerves, including the brain and spinal cord, ...
A method of verifying cardiac capture. A cardiac signal evoked in response to a cardiac stimulation pulse is sensed via an electrode. The sensed signal is lowpass filtered to remove noise and to pass frequencies characteristic of the evoked cardiac signal. The filtered signal is processed to render a waveform signal representing the second derivative of said filtered signal and the second derivative signal is further analyzed to detect a minimum and a maximum amplitude excursion during a selected window of time beginning at a selected time delay following delivery of the cardiac stimulation pulse. The amplitude difference between the minimum and the maximum is measured and compared to a first reference value. The amplitude of the second derivative is measured during a second selected window of time beginning at a selected time delay following delivery of said cardiac stimulation pulse, and compared to a second reference value. A capture detect signal is generated if the amplitude difference exceeds the
A method of verifying cardiac capture. A cardiac signal evoked in response to a cardiac stimulation pulse is sensed via an electrode. The sensed signal is lowpass filtered to remove noise and to pass frequencies characteristic of the evoked cardiac signal. The filtered signal is processed to render a waveform signal representing the second derivative of said filtered signal and the second derivative signal is further analyzed to detect a minimum and a maximum amplitude excursion during a selected window of time beginning at a selected time delay following delivery of the cardiac stimulation pulse. The amplitude difference between the minimum and the maximum is measured and compared to a first reference value. The amplitude of the second derivative is measured during a second selected window of time beginning at a selected time delay following delivery of said cardiac stimulation pulse, and compared to a second reference value. A capture detect signal is generated if the amplitude difference exceeds the
TY - JOUR. T1 - GABAergic inhibition shapes frequency adaptation of cortical activity in a frequency-dependent manner. AU - Heistek, Tim S.. AU - Lodder, Johannes C.. AU - Brussaard, Arjen B.. AU - Bosman, Laurens W. J.. AU - Mansvelder, Huibert D.. PY - 2010/3/19. Y1 - 2010/3/19. KW - Short-term plasticity. KW - Neuronal network. KW - GABA. KW - Voltage-sensitive dye imaging. KW - Benzodiazepine. U2 - 10.1016/j.brainres.2010.01.047. DO - 10.1016/j.brainres.2010.01.047. M3 - Article. C2 - 20114035. VL - 1321. SP - 31. EP - 39. JO - Brain Research. JF - Brain Research. SN - 0006-8993. ER - ...
a, b, Speed profiles of mice after the stimulation of Vglut2+ChR2 CnF (a) and Vglut2+ChR2 PPN (b) neurons. Top panels show the location of optical stimulation in the CnF (a) and the PPN (b). Middle panels show colour plots of individual trials after the stimulation of Vglut2+ChR2 CnF (a) and Vglut2+ChR2 PPN (b) neurons (Fig. 1). The x axis represents time and the y axis represents trials at different stimulation frequencies. Data are aligned to the onset of stimulation (stim.). The colour gradient illustrates speed, with dark blue representing no movement and colours towards yellow representing the increase in speed (up to 120 cm s−1) of the mouse in the linear corridor. Bottom panels show speed profiles obtained as an average of the movements at each stimulation frequency. c, Latencies to onset of locomotion from the stimulation of Vglut2+ChR2 PPN (red) and Vglut2+ChR2 CnF (blue) neurons as a function of the stimulation frequency. Error bars indicate the 25th and 75th percentiles of the ...
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Another important challenge remains in our limited understanding of the specific mechanisms by which stimulation causes its effects, or in other words, what neurophysiological changes occur between the stimulation and the behavioral changes. For example, does applying direct electrical current with short pulses at a low frequency induce a low-frequency oscillation, particularly at the stimulation frequency? Studies sometimes make such implicit assumptions, but the field is lacking a fundamental insight to accept or modify such assumptions. Encouraging advances have been made on this end for TMS (Thut and Miniussi, 2009, Thut and Pascual-Leone, 2009 and Vernet et al., 2013), transcranial alternating current stimulation (tACS; Fröhlich and McCormick, 2010 and Herrmann et al., 2013), and direct brain stimulation (Logothetis et al., 2010 and Tolias et al., 2005). For example, Vernet et al. (2013) used a combined TMS-EEG approach to evaluate the cortical effects of continuous theta-burst stimulation ...
Case Study: System on a Chip for Electric Stimulation: 10.4018/978-1-5225-0190-9.ch011: Integrated circuits have been predominantly designed and developed by large firms and manufacturers; nowadays, any electronic engineer should be able to
Fingerprint Dive into the research topics of Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report. Together they form a unique fingerprint. ...
New Delhi, August 1 The Indian Army is preparing to maintain its current strength of troops, tanks and other weaponry in all key areas in eastern Ladakh in the harsh winter months as a resolution to
Mystim Sizzling Simon E-Stim | Sizzling Simon provides an unprecedented vibration and electrical stimulation at once! No cables or devices Sizzling Simon vibrates, tingles and
The present study has three main results: (1) Processing of different shape stimuli results in activity patterns that in single trials are surprisingly well distinguishable in the local field potential of area V4. (2) Selective attention substantially enhanced the stimulus-dependent differences of these neural activity patterns for the attended stimulus. (3) Behavioral failures went along with a reduction of classification performance. The components of the signal most discriminative for different shapes were contained in the γ-band above 40 Hz and their stimulus-specific characteristics stayed similar during different stimulation periods in a trial. The attention-dependent enhancement of stimulus discriminability cannot be explained by a simple increase of the SNR, but turns out to be most strongly related to a stimulus-specific differential scaling of the frequency components. This scaling results in an enhanced separation between the characteristic frequency patterns in the γ-band for ...
We performed two classes of control experiments to validate the results. First, nontransgenic littermates (n = 9) were injected with Cre-dependent ChR2-EYFP AAV and subjected to the same stimulation paradigm as the experimental animals. Separately, TH::IRES-Cre transgenic mice (n = 9) were injected with Cre-dependent ChR2-EYFP AAV but received no optical stimulation during conditioning to further control for spontaneous preference shifts. Neither control group showed a significant CPP (Fig. 3E right, P , 0.5 by Students t test). Furthermore, we did not find any significant changes in anxiety-related behaviors (Fig. 3G) or in locomotor activity (Fig. 3H) during preference tests and in open field tests (fig. S6).. Next, we tested whether the CPP effect observed was due to an appetitive effect from 50-Hz stimulation or to an aversive effect from 1-Hz stimulation. We compared the effect of each firing modality with no stimulation in two independent cohorts. Consistent with the previous CPP ...
Intraoperative optical imaging (IOI) is a marker-free, contactless, and noninvasive imaging technique that is able to visualize metabolic changes of the brain surface following neuronal activation. Although it has been used in the past mainly for the identification of functional brain areas under general anesthesia, the authors investigated the potential of the method during awake surgery. Measurements were performed in 10 patients who underwent resection of lesions within or adjacent to cortical language or motor sites. IOI was applied in 3 different scenarios: identification of motor areas by using finger-tapping tasks, identification of language areas by using speech tasks (overt and silent speech), and a novel approach-the application of IOI as a feedback tool during direct electrical stimulation (DES) mapping of language. The functional maps, which were calculated from the IOI data (activity maps), were qualitatively compared with the functional MRI (fMRI) and the electrophysiological ...
Positive effects of tDCS in patients in MCS was showed in a recent study published in Neurology. But the effects went down after 1 or 2 hours. To increase the lasting of the effects, a new study will evaluate the effects of tDCS on the left prefrontal dorsolateral cortex for 5 consecutive days in chronic patients in MCS.. 2 sessions of 5 days of stimulation will be realized, one session will be real (anodal stimulation) and one placebo (sham stimulation). After each stimulation, behavioral improvement will be assessed with the Coma Recovery Scale Revised (CRS-R). A final assessment will be done one week after the end of the sessions to assess the long term effect of the tDCS.. Researchers expected to see an improvement of the CRS-r total score at the end of the anodal session and that this improvement persists for a week. ...
Electric Muscle Stimulation Therapy is a new approach in treating various pain issues utilizing electrical muscle stimulation to reach deeper layers of the muscles. It is often used by physical therapists and your local Wesley Chapel chiropractor for localized pain relief especially for muscle pains such as fibromyalgia and muscle strains. The mechanism of the muscle stimulation is it delivers small pulsating currents directly on the muscles, which in turn promotes muscle stimulation, blood circulation and muscle healing.. The main benefit of electrical muscle stimulation therapy is pain relief. The electrical currents allow the muscles to release tension and stress relieving muscle soreness, tightness and body aches. For joint pains, electric muscle stimulation therapy also may improve joint symptoms as relaxation of the smooth muscles around a painful joint can help foster healing from joint inflammation.. Using electric muscle stimulation therapy not only provides effective muscle pain ...
We studied the effects of intense sympathetic stimulation on the chronotropic responses of the heart to subsequent test stimulations of the cardiac autonomic nerves in dogs anesthetized with alpha-chloralose. Such intense sympathetic stimulations (which we refer to as release stimulations) are known to release neuropeptide Y as well as norepinephrine. The changes in cardiac cycle length evoked by vagal and sympathetic test stimulations were progressively more attenuated as we increased the frequency and duration of the antecedent sympathetic release stimulations. We found that 2.5 minutes after a maximal release stimulation (30 Hz for 5 minutes), the mean +/- SEM chronotropic responses to the vagal and sympathetic test stimulations were diminished to 36.5 +/- 1.6% and 54.7 +/- 1.3% respectively, of the prestimulation responses. The mean times for the chronotropic responses to the vagal and sympathetic test stimulations to recover to their control values were 52.0 +/- 1.3 and 63.2 +/- 2.9 ...
TLTE - Tension Lag Time on Electric Stimulation. Looking for abbreviations of TLTE? It is Tension Lag Time on Electric Stimulation. Tension Lag Time on Electric Stimulation listed as TLTE
To determine whether high current strength pacing at the site of origin of ventricular tachycardia (VT) could prevent induction of VT, we studied 11 VTs in 10 patients with chronic coronary artery disease. The left ventricular site of origin of all VT was determined by endocardial catheter mapping. Reproducible VT induction from the right ventricular apex or outflow tract was demonstrated with a pacing current strength equal to twice diastolic threshold (less than or equal to 2.0 mA) with single (two VTs), double (eight VTs), or triple (one VT) extrastimuli following 8 beats of a drive cycle length of 400 to 600 msec. After determination of the baseline VT induction zone (range 10 to 80 msec), repeat induction was attempted while simultaneous pacing was performed during the 8 beat drive train from the left ventricular site of origin with the use of a high current strength (10 mA [two VTs] or 20 mA [nine VTs]) and from the baseline right ventricular site with a current strength equal to twice ...
To investigate whether electrical stimulation promoted axonal regeneration of retinal ganglion cells (RGCs) after optic nerve (ON) crush in adult rats. Transcorneal electrical stimulation (TES), which stimulates the retina with current from a corneal contact lens electrode, was used to stimulate the eye. TES was applied for 1 h immediately after ON crush. Axonal regeneration was determined by anterograde labeling of RGC axons. To examine whether the axonal regeneration was mediated by insulin-like growth factor 1 (IGF-1) receptors, an IGF-1 receptor antagonist, JB3, was injected intraperitoneally before each TES application. Immunostaining for IGF-1 was performed to examine the effects of TES. To test the survival-promoting effects of TES applied daily, the mean density of retrogradely labeled RGCs was determined on day 12 after ON crush. Compared with sham stimulation, the mean number of regenerating axons significantly increased at 250 microm distal from the lesion and increased IGF-1 ...
An automated adaptive muscle stimulation system and method are disclosed. The stimulation system includes at least one electrode assembly adapted to deliver a muscle stimulation signal to the tissue of a user, a sensor system adapted to detect a muscle response, and an electrical stimulation device operably coupled to the at least on electrode assembly and the sensor system, the electrical stimulation device including a control system operable to automatically diagnose at least one characteristic of a muscle from the detected muscle response and adjust at least one parameter of the muscle stimulation signal in response thereto to deliver an adjusted muscle stimulation signal. A dual mode muscle stimulation system adapted to accept first and second data sets and provide first and second levels of treatment data is also disclosed.
An implantable neural stimulation device and method treats peripheral vascular disease of a patient. The device includes a pulse generator that provides stimulation pulses and an implantable lead that applies the stimulation pulses to neural tissue. An activity sensor senses activity level of the patient and a processor, responsive to the activity sensor, controls the provision of the stimulation pulses by the pulse generator. The processor causes the pulse generator to provide stimulation therapy any time the patient is active or when the patient is at rest. The processor further provides long term activity monitoring and closed loop control of neural tissue stimulation levels to adapt the stimulation therapy to changes in the patients condition.
Electrical Muscle Stimulation is a way to provoke muscle contraction by means of electric stimulus. The impulses are generated by a device and delivered through electrodes on the skin in direct proximity to the muscles to be stimulated. The impulses mimic the central nervous system, initiating the contracting of the muscles. EMS is both electrotherapy and muscle training ...
TY - JOUR. T1 - Effect of graded electrical stimulation on blood flow to healthy muscle. AU - Currier, D. P.. AU - Petrilli, C. R.. AU - Threlkeld, A. J.. PY - 1986. Y1 - 1986. N2 - The purpose of this study was to determine whether 2,500-Hz sine-wave electrical stimulation modulated at 50 bursts per second producing graded muscular responses affects blood flow. Healthy volunteer subjects were assigned randomly to an Experimental group (n=14) that received bursts of electrical stimulation to the gastrocnemius muscle or to a Control group (n=14) that received no treatment. Using a Doppler device, pulsatility index (PI) values were determined for multivariate statistical analysis. Electrical stimulation graded to simulate isometric torques equivalent to 10% and then 30% of the subjects isometric maximum voluntary contraction resulted in respective mean increases in PI values of 20.5% and 19.6% over prestimulation PI values. We found no significant difference in PI values between the two levels of ...
Electrical Muscle Stimulation - Electric stimulation therapy involves low levels of electrical impulses delivered to injured tissues to reduce pain and promote faster healing. Patients
The Centers for Disease Control and Prevention (2015) declared that 80% of U.S. adults do not meet exercise recommendations by ACSM. Skeletal muscle contraction has been shown to increase mitochondrial content (energy production) and glucose uptake (decreased insulin resistance). Neuromuscular Electrical Stimulation (NMES) utilizes electrical impulses to induce muscle contractions and can be used as an alternate strategy to induce muscle contraction in sedentary adults. However, it is not clear if NMES induced muscle contraction may improve insulin sensitivity and metabolic health. PURPOSE: The purpose of this study was to investigate the effects of two weeks of NMES on insulin sensitivity, energy expenditure, and body composition in a sedentary population. METHODS: Five female participants (age 23±1 yrs, BMI 24.08±1.36 kg/m2, maximal aerobic capacity 35.4±2.80 ml/kg/min) performed six sessions (20-minutes, 3x/week) of quadriceps electrical stimulation over the course of two weeks. Maximal aerobic
0033] FIG. 2 illustrates a neural stimulator, and further illustrates various neural stimulation parameters that can be adjusted to adjust a neural stimulation therapy, according to various embodiments of the present subject matter. According to various embodiments, the neural stimulator 209 includes modules to set or adjust any one or any combination of two or more of the following pulse features delivered to the neural stimulation electrode(s) or transducer(s): the amplitude 210 of the stimulation pulse, the frequency 211 of the stimulation pulse, the burst frequency 212 of the pulse, the wave morphology 213 of the pulse, and the pulse width 214. Examples of neural stimulation electrodes include nerve cuffs, and intravascularly-fed electrodes to transvascularly stimulate a neural target. Examples of neural transducers include ultrasound, magnetic and light transducers used to stimulate a neural target. The illustrated burst frequency pulse feature 212 includes burst duration 215 and duty cycle ...
RC Walk-In Chiro utilizes Winnipeg Electrical Muscle Stimulation to send electrical impulses to your muscles promoting muscle contractions. Call today!
TY - GEN. T1 - EMS icons. T2 - 2017 ACM International Joint Conference on Pervasive and Ubiquitous Computing and ACM International Symposium on Wearable Computers, UbiComp/ISWC 2017. AU - Dingler, Tilman. AU - Goto, Takashi. AU - Tag, Benjamin. AU - Kunze, Kai Steven. PY - 2017/9/11. Y1 - 2017/9/11. N2 - Electrical Muscle Stimulation (EMS) has recently received an increased amount of attention from the HCI community. It has been used to remote control users for navigation and instrument playing, but also as a method to convey haptic feedback in VR, for example. As EMS devices become commercially available and application research continues, we explore EMS as a modality to convey information through actuation and as a means to induce and communicate emotions and moods. In this position paper, we present the results from two focus groups on using EMS for interpersonal communication as a way to send and receive emoticons through electrical stimulation. We argue that so-called EMS Icons have the ...
Electrical Muscle Stimulation - Here at Forzani Family Chiropractic, we are proud to offer e-stim to our patients. Stimulation can be a fantastic tool to assist you in feeling better.
electro muscle stimulation_Electrical muscle stimulation WikipediaElectrical muscle stimulation (EMS), also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is the elicitation of muscle EMS
Determination of Excitation Thresholds for Retina Ganglion Cells Using Biphasic and Monophasic Stimulation Pulses to be Designed for High Resolution Epiretinal Prosthesis ...
TY - GEN. T1 - Effect of muscular strengthening with electrical stimulation on sit-to-stand motion in young and elderly persons. AU - Galli, M.. AU - Crivellini, M.. PY - 1998. Y1 - 1998. N2 - The ability to get up from a chair is an important component in maintaining independence for elderly persons and for individuals with disabilities. The main aim of this work is to investigate the effect of muscular strengthening on sit-to-stand (STS) movement to get round the muscular weakness that often occur in elderly people. The sit-to-stand movement of 18 young persons and 10 elderly healthy subjects were acquired before and after an electrical stimulation (ES) strengthening cycle. Experimental data collected by using an optoelectronic system (ELITE), an EMG telemetric equipment and a force platform were analyzed by using a biomechanical planar model. The rising strategies and hip knee and ankle joint torques in the two different groups were calculated before and after ES cycle. The results showed ...
Start Over You searched for: Authors Beard, George M. (George Miller), 1839-1883 ✖Remove constraint Authors: Beard, George M. (George Miller), 1839-1883 Subjects Electric Stimulation Therapy ✖Remove constraint Subjects: Electric Stimulation Therapy Titles Medical and surgical cases treated by electricity ✖Remove constraint Titles: Medical and surgical cases treated by electricity Publication Year 1874 ✖Remove constraint Publication Year: 1874 Dates by Range 1850-1899 ✖Remove constraint Dates by Range: 1850-1899 ...
Cyclosporin A administration is associated with an increased incidence of hypertension. To evaluate the direct effects of the drug on the contractile responses of vascular tissue to adrenergic stimuli, rat caudal artery ring segments were studied before and after the addition of cyclosporin A or its ethanol vehicle in vitro. In a dose-related manner, cyclosporin A augmented the contractile response to transmural nerve stimulation, with a highly significant (p less than 0.001 relative to that produced by the vehicle) lowering of the stimulation rate, a 50% of maximum contractile response (ED50) that elicited. The difference between pretreatment and treatment maximal responses to transmural nerve stimulation was also significantly greater (p less than 0.01) in the cyclosporin A-treated preparations than in those receiving the vehicle. In similar experiments, the responses to exogenous norepinephrine were not significantly affected. The effect of cyclosporin A on transmural nerve stimulation was ...
a valid model for myotonic dystrophy, was assessed, using an in vivo force assessment device, used in conjunction with EMG recording. The aim of the study was to verify whether the muscle force assessment device we developed was capable to sensitively detect the typical characteristics of myotonic muscle. To date, two wild-type and four myotonic female mice have been assessed. After anesthetic induction by isoflurane, the mice were positioned in the apparatus. Hindlimb muscles were stimulated noninvasively by electrodes placed on the muscle of the leg being stimulated. After establishing optimal muscle length, muscle force was assessed after single pulse stimulation at supramaximal voltage followed by double, triple and quadruple pulses. Both legs from each animal were tested and included in the analyses. Muscle force characteristics (peak force, half relaxation time, and area under the force curve (AUC)) and EMG data were recorded and analyzed. Peak forces generated in the myotonic mice were ...
Various aspects of the present subject matter provide a filter module. In various embodiments, the filter module comprises an input, an output, a signal path from the input to the output, a filter and a switch. The filter has a transfer response to attenuate a frequency of a neural stimulation signal. The switch is adapted to place the filter in the signal path when the neural stimulation signal is applied and to remove the filter from the signal path when the neural stimulation signal is not applied. Other aspects are provided herein.
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The effects of dl-metanephrine (300 µg/kg i.v.) were determined on responses of the nictitating membrane to norepinephrine, to phenylephrine and to nerve stimulation. After the administration of metanephrine there was an increase in responses of the normal nictitating membrane to norepinephrine and to pnenylephrine in the lower part of the dose-response curve. The rest of the dose-response curve was practically superimposed on the corresponding controls. A similar pattern was observed for the denervated (2 days) nictitating membrane. Responses to pre- and to postganglionic stimulation obtained after the administration of metanephrine were increased for the range of low frequencies of stimulation. The rest of the frequency-response curve was superimposed on the control curve. The increase in responses in the lower part of the response curves was shown to be due to the additive effects of metanephrine and the injected sympathomimetic amine or the endogenously released norepinephrine. It is ...
Welcome to Odstock Medical the leading manufacturer of Clinical Functional Electrical Stimulation systems (FES) together with the associated treatments for patients who are effected by a dropped foot or upper limb disability.
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The Report provides a detailed Global Electrical Stimulation Devices ESD Industry overview along with the analysis of industrys gross margin, cost structure, consumption value, and sale price, Processing Techniques, Network Management, Services Offered, Related Softwares Market, Social Media Marketing, Cost Structure, Supply Chain, Development Management Techniques, Retailers Analysis, Financial Support, business Strategies, Marketing Channels, Market Entry Strategies, Industry Development Challenges and Opportunities, Investment Plans, Economic Impact on Electrical Stimulation Devices ESD Market.. Inquiry about Report at: Global Electrical Stimulation Devices ESD Market Chapterwise Description :-. The First Chapter covers Electrical Stimulation Devices ESD basic introduction, marketplace overview, product scope, market opportunities, market risk, and market driving force. The Second Chapter deals ...
1. Release of [3H]noradrenaline during peri-arterial nerve stimulation and its inhibition by the presynaptic α-adrenoceptor mechanism were studied in the isolated perfused kidney from spontaneously hypertensive and Wistar-Kyoto rats.. 2. A frequency related vasoconstriction as well as [3H]noradrenaline release were observed over the stimulating range of 0.25-32 Hz in both the Wistar-Kyoto and spontaneously hypertensive rats. The spontaneously hypertensive rat kidneys exhibited both an increased vasoconstrictor response and a greater [3H]noradrenaline release when compared with the Wistar-Kyoto rat kidneys.. 3. Presynaptic inhibition of [3H]noradrenaline release was evaluated at 2 Hz by using the α-adrenoceptor agonist, tramazoline. Increasing concentrations of tramazoline from 2 × 10−9 mol/l to 2 × 10−7 mol/l caused a dose-dependent decrease in the stimulus-induced release of [3H]noradrenaline in spontaneously hypertensive rats but not in Wistar-Kyoto rats. Only 2 × 10−7 mol/l ...
Various programming techniques are described for medical devices that deliver electrical stimulation therapy that may include mapping between discrete electrical stimulation parameters and a graphical view of the electrical stimulation representing a stimulation zone generated by the parameters. In one example, a method includes receiving, via a programmer for an electrical stimulator, user input that graphically manipulates at least one of size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer, and defining a program to control delivery of electrical stimulation therapy based on the user input.
Percutaneous tibial nerve stimulation - Electrical impulses are applied to the nerves that control bladder function.. Choose Spire Cambridge Lea Hospital.
Currently, the study of nociception in humans relies mainly on thermal stimulation of heat-sensitive nociceptive afferents. To circumvent some limitations of thermal stimulation, it was proposed that intra-epidermal electrical stimulation (IES) could be used as an alternative method to activate nociceptors selectively. The selectivity of IES relies on the fact that it can generate a very focal electrical current and, thereby, activate nociceptive free nerve endings located in the epidermis without concomitantly activating non-nociceptive mechanoreceptors located more deeply in the dermis. However, an important limitation of IES is that it is selective for nociceptors only when very low current intensities are used. At these intensities, the stimulus generates a very weak percept, and the signal-to-noise ratio of the elicited evoked potentials (EPs) is very low. To circumvent this limitation, it was proposed that the strength of the nociceptive afferent volley could be increased through temporal ...
Part I Theory and Applications; Introduction - Excitable Tissue. Predictive Models. Overview.; Theoretical Foundations - Basic Equations. Cable Equation Relationships. Spatial Relationships. Mechanisms of Interaction. Alternative Models for Membrane Electrodynamics. Research Topics for Chapter 2.; Excitation Relationships - Threshold of Excitation. Strength-Duration Relationships. Power Supply Demand. Nonlinear Interaction of Multiple Stimulus Waveforms. Repetitive Stimulus Effects. Research Topics for Chapter 3. ; Threshold Criteria in Practical Applications - General Principles. Threshold Relationships. Research Topics for Chapter 4.; Selective Activation and Inhibition - General Aspects. Fiber Diameter Relationships. Selective Activation or Inhibition. Research Topics for Chapter 5.; Model Application to C-Fibers and the Heart - General Objectives. Electrostimulation of Nerve Fibers and Cardiac Muscle. Electrostimulation Characteristics of Cardiac Tissue. SENN Model Adaptation for A-Fibers, ...
Adenylyl cyclases contain two conserved homologous cytoplasmic domains (C1 and C2) that form the catalytic core of the enzyme [21]. Forskolin appears to induce the assembly of these two domains by interacting with the catalytic cleft [21-23]. The affinity between C1 and C2 is also facilitated by Gαs binding. These data have been confirmed by the finding that Forskolin and Gαs stimulate synergistically the cyclase activity [22]. In the presence of Gαs the affinity of Forskolin for the dimer C1/C2 is high (Kd = 0.1 μM), which suggests a stronger affinity for the complete cyclase molecule [23]. The site of interaction of the cyclase (type I or II) for beta/gamma has been located in the C1 b region. This site is independent of the Gαs and Forskolin interaction domains[24]. These findings argue in favor of isolating the cyclase(s) and its associated proteins using Forskolin-agarose affinity chromatography although this procedure enriches indistinctly the different isoforms of the cyclase family. ...
Background: Most U.S. adults (80%) do not meet minimum exercise recommendations by ACSM (CDC, 2015). Using an in vitro primary cell culture model, we and others have shown that muscle contraction induced by electrical stimulation results in increased glucose transporter 4 (GLUT4) protein, glucose uptake and mitochondrial content. Neuromuscular electrical stimulation (NMES) is a novel alternate strategy to induce muscle contraction, using electrical impulses. However, effectiveness of NMES induced muscle contraction to improve insulin sensitivity and energy expenditure is not clear. The purpose of this study was to investigate the effects of four weeks of NMES on insulin sensitivity in a sedentary overweight/obese population. Methods: Sedentary overweight/obese participants (n=10; age: 36.8 ± 3.8 years; BMI= 32 ± 1.3 kg/m2) were randomized into either a control or NMES group. All participants received bilateral quadriceps stimulation (12 sessions; 30 minutes/session; 3 times/week) either using low
Electric muscle stimulation trains your muscles in a way that traditional workouts alone cant. EMS, also known as neuromuscular electric stimulation, muscle stim, or e-stim, is delivered through electronic pulses to your nerve fibers in order to create involuntary muscle contractions. Unlike TENS, EMS waveforms activate fast twitch and slow twitch muscle fibers allowing the muscles to be stimulated to the point of exhaustion (relaxation) thus healing them to become stronger. This is similar to weight training. Muscles support joints and ligaments creating better support.. ...
A Functional Electric Stimulation unit (FES) stimulates nerves and muscles to give the patient more natural movement and stability. It is often used for patients with stroke, multiple sclerosis, cerebral palsy and brain or spinal cord injuries. It re-educates muscles to reduce muscle loss, increase local blood circulation and maintain or improve a range of motion ...
0 UserClasses Electrode An current injection electrode inserted in the middle of the current section which can be switched between current and voltage clamp modes and can do simple voltage clamp families. usage: section e = new Electrode([xplacement, yplacement]) e.stim and can used to set parameters programatically. Electrode can be saved in a .session file and is best used anonymously so that it is dismissed and point processes deleted when the graphic is dismissed. ?1 IClamp Switches the Electrode to single pulse current injection. Uses IClamp point process. ? del Time (ms) of the onset of the current stimulus relative to t = 0. ? dur Duration (ms) of the current stimulus ? amp Amplitude (mV) of the current stimulus ?1 VClamp Switches the Electrode to two electrode voltage clamp. Uses VClamp point process that allows up to three level changes. The clamp is set to be ideal. ?2 dur0 dur1 dur2 Duration in milliseconds of each level change starting at t=0. Each level is concatenated. At t = ...
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We also were able to fit Hunter with a loaner cart. The therapy seems to be working. By mid-April Hunter he was able to stand and support himself for 20 seconds with balance support, which is continuing to progress. On 5/20 Vicki noted he was walking independently on the hydro-treadmill and we no longer needing to use his tail for balance support. Hunter is progressively improving his mobility with his right rear limb, and a video from Vicki is starting to show movement in the left rear. From a medical point of view, Hunter is also continuing to improve. Hunter is currently on a 12 week course of antibiotics and repeat radiographs are showing no further damage in the hip joint. Vicki is continuing to bring Hunter to therapy and perform the neuromuscular electrical stimulation at home, with the goal of getting his mobility back to 100%. Great job by Vicki and keep with it Hunter!. ...
With just-suprathreshold current pulses, FS cells often displayed a considerable delay before the first spike, whereas GIN cells did not (cf. Fig. 2, C and D, top panels). In addition, GIN cells often displayed an afterdepolarization (ADP) following low-frequency action potentials (Fig. 2C, inset; cf. Halabisky et al. 2006). At higher levels of stimulus current, spike frequency adaptation was evident in GIN cells (Fig. 2D, bottom), but not in FS cells (Fig. 2D, bottom). Finally, at higher stimulus currents, the peak of the first action potential in GIN cells was the most positive in the train and the trough of the first afterhyperpolarization (AHP) was the most negative (Fig. 2C, bottom). By contrast, the action potential heights and AHP magnitudes of FS cells changed little under similar conditions (Fig. 2D, bottom). The firing of GIN cells also differed from that of RS cells, whose second action potential peak was substantially more negative than the first and whose first AHP was the most ...
The behavioral effects of direct electrical stimulation of the cingulum bundle, a white matter tract in the brain, were confirmed in two other epilepsy patients undergoing diagnostic monitoring. The findings are scheduled for publication in the Journal of Clinical Investigation. Videos of the effects of cingulum bundle stimulation are available, with the patients identity obscured.. Emory neurosurgeons see the technique as a potentially transformative way to calm some patients during awake brain surgery, even for people who are not especially anxious. For optimal protection of critical brain functions during surgery, patients may need to be awake and not sedated, so that doctors can talk with them, assess their language skills, and detect impairments that may arise from resection.. Even well-prepared patients may panic during awake surgery, which can be dangerous, says lead author Kelly Bijanki, PhD, assistant professor of neurosurgery. This particular patient was especially prone to it ...
Model Number: BK111A-#0954 Brand Name: OEM Key Specifications/Special Features: Body building abdomen muscle stimulation slimming beltBody building slender shaper muscle stimulation slimming belt Electric acupuncture LCD display Lithium batter...
Welcome to Odstock Medical the leading manufacturer of Clinical Functional Electrical Stimulation systems (FES) together with the associated treatments for patients who are effected by a dropped foot or upper limb disability.
... thermal and electrical stimulation, but is perhaps most frequently a response to mechanical stimulation during capture by a ... have used electric shocks to examine this response (See sections on "Electrical stimulation" and "Operant conditioning"). ... Electrical stimulation[edit]. The sea-slug, Tritonia diomedia, possesses a group of sensory cells, "S-cells", situated in the ... To receive electrical stimulation of the brain, the snail was required to displace the end of a rod. When pressing the rod ...
During the 1940s, however, the U.S. War Department, investigating the application of electrical stimulation not just to retard ... Institute of Electrical and Electronics Engineers, "The IEEE standard dictionary of electrical and electronics terms". 6th ed. ... Barnes R, Shahin Y, Gohil R, Chetter I (April 2014). "Electrical stimulation vs. standard care for chronic ulcer healing: a ... Mollon B, da Silva V, Busse JW, Einhorn TA, Bhandari M (November 2008). "Electrical stimulation for long-bone fracture-healing ...
"Gastric Electrical Stimulation". The Regents of The University of California. Retrieved 12 March 2016.. ... Electric[edit]. Electrical implants are being used to relieve pain and suffering from rheumatoid arthritis. The electric ... "Arthritis sufferers offered hope after electrical implants leave". The Independent. 23 December 2014. Retrieved 1 February 2019 ... implant is embedded in the neck of patients with rheumatoid arthritics, the implant sends electrical signals to electrodes in ...
"Behavioral response of sharks to electric stimulation". Bulletin of Seikai National Fisheries Research Institute. 78: 13-30.. ... The stargazer buries itself in sand and can deliver electric shocks as well as venom. It is a delicacy in some cultures (the ... The great hammerhead uses its hammer both to locate electrical signatures of stingrays buried in the sand and to pin them down ... The whitetip reef shark is highly responsive to olfactory, acoustic, and electrical cues given off by potential prey. Its ...
"Electrical stimulation of the heart in man". Br Med J. 1 (1468): 348-50. doi:10.1136/bmj.1.1468.348. PMC 2154721. PMID 20752595 ... "IEEE Milestone in Electrical Engineering and Computing". Retrieved September 5, 2009.. *^ "Paul Maurice Zoll". Harvard Gazette ... In 1950, Canadian electrical engineer John Hopps designed and built the first external pacemaker based upon observations by ... Note the circle around one of the sharp electrical spikes in the position where one would expect the P wave. ...
Patterson, Michael; Kesner, Raymond (1981). Electrical Stimulation Research Techniques. Academic Press. ISBN 0-12-547440-7.. ... This coupling results in an electric body force in the bulk liquid, outside the electric double layer, that can generate ... These instabilities are caused by a coupling of electric fields and ionic conductivity gradients that results in an electric ... In such case, the moving structure acts as an electric motor Practical fields of interest of EHD are the common air ioniser, ...
Transcutaneous electrical nerve stimulation. References[edit]. *^ a b c d McKenzie-Brown, Anne Marie (November 1, 2016). " ... spinal cord stimulation, deep brain stimulation, and motor cortex stimulation. ... Shealy, C. N.; Mortimer, J. T.; Reswick, J. B. (July 1967). "Electrical inhibition of pain by stimulation of the dorsal columns ... "Complications of Spinal Cord Stimulation and Peripheral Nerve Stimulation Techniques: A Review of the Literature". Pain ...
"Tas Cricket - Electrical Stimulation". Retrieved 23 April 2018.. ...
Low level "baseline" release also occurs without electrical stimulation. The released neurotransmitter may then move across the ... Neurons do not touch each other (except in the case of an electrical synapse through a gap junction); instead, neurons interact ... In response to a threshold action potential or graded electrical potential, a neurotransmitter is released at the presynaptic ... In its direct actions in influencing a neuron's electrical excitability, however, a neurotransmitter acts in only one of two ...
Using electrical stimulationEdit. Intramuscular electrical stimulation (IMES) of muscle tissue has been used in various ... Kosek E, Hansson P (2003). "Perceptual integration of intramuscular electrical stimulation in the focal and the referred pain ... Lastly, the threshold for the local pain stimulation and the referred pain stimulation are different, but according to this ... The frequency of the electrical pulse can also be controlled. For most studies a frequency of about 10 Hz is needed to ...
Electrical stimulation of partial limb regeneration in mammals. Becker RO, Spadaro JA. Bull N Y Acad Med. 1972 May;48(4):627-41 ... Mollon B, da Silva V, Busse JW, Einhorn TA, Bhandari M (November 2008). "Electrical stimulation for long-bone fracture-healing ... Kooistra BW, Jain A,1 and Hanson BP (April-June 2009). "Electrical stimulation: Nonunions". Indian J Orthop. 43 (2): 149-55. ... His work showed that living organisms and animals show a direct current of electric charge which is measurable from their body ...
Apply heat, ice, or electrical stimulation[6]. *Take nonsteroidal anti-inflammatory medications for 7-10 days[5] ...
... ing can be induced by electric scalp stimulation, study finds. *A look at four psychology fads - a comparison of est ...
"Electrical stimulation of human fusiform face-selective regions distorts face perception". J Neurosci. 32 (43): 14915-20. doi: ... Electrical stimulation of these functional clusters selectively distorts face perception, which is causal support for the role ...
Zoll, PM (November 1952). "Resuscitation of the heart in ventricular standstill by external electric stimulation". New England ... electric pacemaker," he wrote. "For the first time it was possible to keep a patient alive during ventricular asystole lasting ...
"Electrical stimulation of partial limb regeneration in mammals". Bulletin of the New York Academy of Medicine. 48 (4): 627-41. ... using electrical stimulation, has shown promising results for rats[78] and mammals in general.[79] ... Specifically, cytokine stimulation of cells leads to expression of genes that change cellular functions and suppress the immune ... Becker RO (January 1972). "Stimulation of partial limb regeneration in rats". Nature. 235 (5333): 109-11. Bibcode:1972Natur.235 ...
Young W (2015). "Electrical stimulation and motor recovery". Cell Transplantation. 24 (3): 429-46. doi:10.3727/096368915X686904 ... epidural spinal stimulation, and wearable robotic exoskeletons. Spinal cord injury can be traumatic or nontraumatic, and can be ...
Soffer, Edy E (2012). "Gastric Electrical Stimulation for Gastroparesis". Journal of Neurogastroenterology and Motility. 18 (2 ...
Siegert, M.; Tan, A. (2019). "Electric stimulation of ammonotrophic methanogenesis". Frontiers in Energy Research. 7: 17. doi: ... At the same time, they unload the liberated electrons onto the anode, producing electrical current. This electrical current can ... Another, still unexplored, reaction mechanism involves anaerobic ammonium oxidation on anodes of bio-electrical systems. Such ...
Mindes, Janet; Dubin, Mark J.; Altemus, Margaret (November 15, 2014). "Chapter 11 Cranial Electric Stimulation". In Knotkova, ... February 17, 2012 Electrical Stimulators Need High-Risk Rating, Says FDA Panel Staff, Sleep Review. June 11, 2014 FDA To ... Rigorous clinical trial evidence is lacking on the use of cranial electrotherapy stimulation (CES) in acute depression. Thus, ... Kavirajan HC, Lueck K, Chuang K (2014). "Alternating current cranial electrotherapy stimulation (CES) for depression". Cochrane ...
Rolston JD, Desai SA, Laxpati NG, Gross RE (October 2011). "Electrical stimulation for epilepsy: experimental approaches". ... Therefore, the main goal of neural decoding is to characterize how the electrical activity of neurons elicit activity and ... a neuron's electric potential fluctuates around its resting potential due to a constant influx and efflux of sodium and ... they may find what appears to be random electrical activity. These neurons are actually firing in response to the lower level ...
Cochrane Wounds Group) (January 2020). "Electrical stimulation for treating pressure ulcers". The Cochrane Database of ... electrical stimulation). Reliable scientific evidence to support the use of many of these interventions, though, is lacking. ... electrical stimulation). Reliable scientific evidence to support the use of many of these interventions, though, is lacking. ... of randomized controlled trials concluded that more research is needed to determine whether or not electrical stimulation is an ...
Electrical stimulation can promote nerve regeneration. The positive effect of electrical stimulation on nerve regeneration is ... Other methods of preventing peripheral nerve injury include electrical nerve stimulation and ultrasonography. Electrical ... Electrical stimulation can directly accelerate the expression of cAMP both in neurons and Schwann cells. cAMP is a molecule ... Electrical stimulation also results in the influx of calcium ion, which further triggers multiple regeneration pathways. The ...
using evoked potentials and electrical stimulation. Experiments involving ablation of the second somatosensory cortex in ... Areas S2 in the left and right hemispheres are densely interconnected, and stimulation on one side of the body will activate ... and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation". J ...
Moreover, induction of electrical stimulation to the claustrum has been shown to cause inhibition reading, a blank stare, and ... Electrical stimulation in the dorsal claustrum of cats elicits excitatory responses within the visual cortex. The claustrum is ... A 2019 study consisting of electrical stimulation of the claustrum found no disruption of consciousness in any of the five ... However, a recent study consisting of electrical stimulation of the claustrum found no disruption of consciousness in any of ...
Functional electrical stimulation (FES) uses bursts of short electrical pulses to generate muscle contraction. Application of ... Milos R Popovic is a scientist specializing in Functional Electrical Stimulation (FES) and neurorehabilitation. As of 2018, he ... A randomized trial of functional electrical stimulation for walking in incomplete spinal cord injury: Effects on walking ... Thrasher, T.A.; Popovic, M.R. (July 2008). "Functional electrical stimulation of walking: Function, exercise and rehabilitation ...
ISBN 978-0-8071-2553-3. Baumeister, Alan A. (2000). "The Tulane Electrical Brain Stimulation Program. A historical Case Study ... to apply electric shocks to test subjects (who were actors and did not really receive electric shocks). In 1971, Stanford ... and applied numerous high voltage electric shocks to them over the course of weeks or months, often administering up to 360 ...
Functional electrical stimulation for neuromuscular applications. Annu. Rev. Biomed. Eng., 7, pp. 327-360. Peckham, P.H., Keith ... and relied on electrical stimulation to control neuromuscular activation. This neural prosthetic, called Freehand, was further ... the director of the Functional Electrical Stimulation Center, and founding the non-profit Institute for Functional Restoration ... where his research involves using functional electrical stimulation to restore function to upper extremities, including hands ...
Functional electrical stimulation as a localization test in Neurological examination.. *identified progressive bulbar paralysis ... He developed a non-invasive technique of muscle stimulation that used faradic shock on the surface of the skin, which he called ... invited Sir David Ferrier to his asylum laboratory to undertake experiments involving the electrical stimulation of motor ... He is known, in particular, for the way he triggered muscular contractions with electrical probes, recording the resulting ...
Deep brain stimulation sends regulated electrical pulses to the target. In patients with tardive dyskinesia treated with DBS, ... The direct pathway is modulated by stimulation of the GPi by the external globus pallidus and subthalamic nucleus, via the ... Dong, S.; Zhuang, P.; Zhang, X.-H.; Li, J.-Y.; Li, Y.-J. (2012-01-01). "Unilateral deep brain stimulation of the right globus ... The internal globus pallidus is the target of deep brain stimulation (DBS) for these diseases. ...
One important rehabilitation tool for muscle atrophy includes the use of functional electrical stimulation to stimulate the ... D.Zhang et al., Functional Electrical Stimulation in Rehabilitation Engineering: A survey, Nenyang technological University, ... although dietary leucine itself can lead to a modest stimulation of protein synthesis by producing a small amount of HMB, ...
Electrical or chemical stimulation of the rat hippocampus causes strengthening of synaptic signals, a process known as long- ... In "kindling", repeated stimulation of hippocampal or amygdaloid neurons in the limbic system eventually leads to seizures in ... They then paired noxious electrical stimulus to the tail with a touch to the siphon, causing the gill withdrawal response to ... Thus, kindling has been suggested as a model for temporal lobe epilepsy in humans, where stimulation of a repetitive type ( ...
Is electrical brain stimulation used (like drugs) to produce pleasures in humans in other settings than scientific experiments? ... 1.1 Is electrical brain stimulation used (like drugs) to produce pleasures in humans in other settings than scientific ... The main electric flow in a metal like wire is carried by electrons. Electric flow will also be accompanied by a magnetic field ... But an electric current isn't always a flow of free electrons. When we send electric current through sea water, we get ...
The use of a transcutaneous electrical nerve stimulation device has been shown to alleviate hyperalgesia.[28][29] ... "Effectiveness of transcutaneous electrical nerve stimulation for treatment of hyperalgesia and pain". Current Rheumatology ... One major pathway being through stimulation of the nociceptin receptor,[8][9][10] and blocking this receptor may therefore be a ... Stimulation of nociceptive fibers in a pattern consistent with that from inflammation switches on a form of amplification in ...
... and stimulation by light causes its structure to change to all-trans-retinal. This structural change causes it to activate a ... pathway is the mechanism by which the energy of a photon signals a mechanism in the cell that leads to its electrical ...
... electrical muscle stimulation, therapeutic ultrasound, and moist heat.[21] Some mixers also use techniques from alternative ... or they may use an electric device known as an "ArthroStim" for assessment and spinal manipulations.[77] Insurers in the US and ... electrical modalities, complementary procedures, and lifestyle advice.[3] ...
The electrodes contact the heart directly through the chest, allowing stimulation pulses to pass through the body. Recipients ... Further standards are IEC 60601-1 which is for electrical devices (mains-powered as well as battery powered), EN 45502-1 which ...
Modern hunters do not normally use any of the elaborate show clips and just require a very simple cut with electric clippers an ... kindly demeanor and they adore playing games that spark their interest in physical and social stimulation. For example, with ...
Manipulations of brain activity can be performed with direct electrical brain stimulation, magnetic brain stimulation using ... transcranial magnetic stimulation, psychopharmacological manipulation, optogenetic manipulation, and by studying the symptoms ...
... "might be brought about by direct stimulation of someone's brain, in the absence of any relevant desire or intention on the part ... the build-up of electrical signal called the readiness potential (after German Bereitschaftspotential, which was discovered by ...
The stimulation of the hair cells sends the message to the brain that acceleration is taking place. The ampullae open into the ... The bending of these stereocilia alters an electric signal that is transmitted to the brain. Within approximately 10 seconds of ... In the horizontal canal, ampullopetal flow is necessary for hair-cell stimulation, whereas ampullofugal flow is necessary for ...
A digital signal processor based functional electrical stimulation system with its user interface design. In Engineering in ... 8. Wu, H. C., Young, S. T., & Kuo, T. S. (2002). A versatile multichannel direct-synthesized electrical stimulator for FES ... Han-Chang, W., Shuenn-Tsung, Y., & Te-Son, K. A versatile multichannel direct-synthesized electrical stimulator for FES ...
Schmidt, Louis A.; Trainor, Laurel J. (2001). "Frontal brain electrical activity (EEG) distinguishes valence and intensity of ... Stewart, Lauren; Walsh, Vincent; Frith, UTA; Rothwell, John (2006). "Transcranial Magnetic Stimulation Produces Speech Arrest ... Koelsch, Stefan; Maess, Burkhard; Grossmann, Tobias; Friederici, Angela D. (2003). "Electric brain responses reveal gender ... Electric Brain Responses Reveal Musical Competence and Gender Differences". Journal of Cognitive Neuroscience. 15 (5): 683-93. ...
Deep Brain Stimulation (DBS) is a surgery where doctors put wires that can carry corrective electric signals inside a patient's ... There are two places in the brain where the stimulation is placed. The stimulation is either put in the thalamus[11][12][13][14 ... Nuttin B, Cosyns P, Demeulemeester H, Gybels J, Meyerson B (1999). "Electrical stimulation in anterior limbs of internal ... "A putative generalized model of the effects and mechanism of action of high frequency electrical stimulation of the central ...
Mechanical pressure of varying strength and frequency can be applied to the corpuscle by stylus, and the resulting electrical ... Itch sensations are caused by stimulation of free nerve ending from chemicals.[5] ... They have small receptive fields and produce transient responses to the onset and offset of stimulation. ... They also produce sustained responses to static stimulation, but have large receptive fields. ...
... pre-market approval for an upper airway stimulation system that senses respiration and delivers mild electrical stimulation to ... "Electrical stimulation of the hypoglossal nerve in the treatment of obstructive sleep apnea". Sleep Medicine Reviews. 14 (5): ... Neurostimulation is currently being studied as a method of treatment;[63] an implanted hypoglossal nerve stimulation system ... FDA "Premarket Approval (PMA) Inspire II Upper Airway Stimulation System" U.S. Food and Drug Administration. April 30, 2014. ...
"Effect of Putative Pheromones on the Electrical Activity of the Human Vomeronasal Organ and Olfactory Epithelium."Science ... "Emotion, Olfaction, and the Human Amygdala: Amygdala Activation during Aversive Olfactory stimulation." JNeurosci. 14 Feb. 1997 ... causing an electrical response that spreads through the sensory neuron to the olfactory nerve fibers at the back of the nasal ...
"Electrical stimulation of the heart in man". Br Med J. 1 (1468): 348-50. doi:10.1136/bmj.1.1468.348. PMC 2154721. PMID 20752595 ... "Electrical Stimulation of the Heart in Man - 1899", Accessed Jan 27, 2014. ... "IEEE Milestone in Electrical Engineering and Computing". Retrieved September 5, 2009.. *^ Harvard News Office. "Harvard Gazette ... In 1950, Canadian electrical engineer John Hopps designed and built the first external pacemaker based upon observations by ...
Cortical stimulation mapping. *Diffusion MRI (dMRI) - includes diffusion tensor imaging (DTI) and diffusion functional MRI ( ... ElectricalEdit. *Event-related potential positive and negative 10µ to 100µ Volts (µ is millionths) responses, measured via ... The first negative and positive swings (see Visual N1, C1 and P1 (neuroscience)) in response to visual stimulation are of ... Neurostimulation (in research stimulation is frequently used in conjunction with imaging). *Positron emission tomography (PET) ...
Repetitive transcranial magnetic stimulation had been studied in ALS in small and poorly designed clinical trials; as of 2013[ ... and electric shock.[58][59] There is a tentative association with exposure to various pesticides, including the organochlorine ... Fang J, Zhou M, Yang M, Zhu C, He L (May 2013). "Repetitive transcranial magnetic stimulation for the treatment of amyotrophic ... Excitotoxicity, or nerve cell death caused by high levels of intracellular calcium due to excessive stimulation by the ...
... and Hermann von Helmholtz demonstrated that the electrical excitation of neurons predictably affected the electrical states of ... generally using physiological techniques that include measurement and stimulation with electrodes or optically with ion- or ... While Luigi Galvani's pioneering work in the late 1700s had set the stage for studying the electrical excitability of muscles ... For example, in 1952, Alan Lloyd Hodgkin and Andrew Huxley presented a mathematical model for transmission of electrical ...
... electrical stimulation, electrical therapy and duration of treatment by focused ultrasound 8-70...8-72: measures for the ...
Another technique is the real-time tracking and localization of one or more small implantable electric devices implanted inside ... "Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by ...
Increased sympathetic stimulation is usually due to physical or psychological stress. This is the basis for the so-called fight ... Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within ... An increase in sympathetic nervous system stimulation causes the heart rate to increase, both by the direct action of ... flight response, but such stimulation can also be induced by stimulants such as ephedrine, amphetamines or cocaine. Certain ...
Stimulation of the larynx by ingested matter produces a strong cough reflex in order to protect the lungs. ... Also of help in the action of peristalsis is the basal electrical rhythm that determines the frequency of contractions.[35] The ...
This is the basis for the so-called fight-or-flight response, but such stimulation can also be induced by stimulants such as ... such as with electrical problems within the heart). ... Increased sympathetic stimulation is usually due to physical or ... An increase in sympathetic nervous system stimulation causes the heart rate to increase, both by the direct action of ... as pheochromocytoma can also cause epinephrine release and can result in tachycardia independent of nervous system stimulation ...
... "programmed electrical stimulation").. Medical treatmentEdit. *Initial administration and monitoring of the effect of drugs for ... as well as of cardiac responses to programmed electrical stimulation. These studies are performed to assess arrhythmias, ... An electrophysiology study is any of a number of invasive (intracardiac) and non-invasive recording of spontaneous electrical ... Electrophysiologists are trained in the mechanism, function, and performance of the electrical activities of the heart. ...
Transcutaneous electrical nerve stimulation has also shown to be useful in the management of post-thoracotomy pain. ... Assessing the effects of transcutaneous electrical nerve stimulation (TENS) in post-thoracotomy analgesia. Rev Bras Anestesiol ...
When an electrical impulse begins in any part of the heart, it will spread throughout the myocardium and cause a contraction; ... Conditions that increase automaticity include sympathetic nervous system stimulation and hypoxia. The resulting heart rhythm ... Not all the electrical impulses of the heart produce audible or palpable beats; in many cardiac arrhythmias, the premature or ... It does this by applying an electric shock to the heart, after which sometimes the heart will revert to a rhythm that can once ...
Gastric electrical stimulation is a pacemaker-like device with electrical connections to the surface of the stomach. The device ... Gastric electrical stimulation, also known as implantable gastric stimulation, is the use of specific devices to provide ... Levinthal, DJ; Bielefeldt, K (January 2017). "Systematic review and meta-analysis: Gastric electrical stimulation for ... Chiu, JD; Soffer, E (January 2015). "Gastric electrical stimulation for obesity". Current gastroenterology reports. 17 (1): 424 ...
Learn about your options, from transcutaneous electrical nerve stimulation (TENS) to interferential current (IFC). ... Nerve stimulation - or neuromodulation - is an alternative to medication for treating arthritis pain. ... Pulsed Electrical Stimulation (PES). What it is: PES delivers a current to the site of pain via electrodes placed on the skin. ... Electrical Nerve Stimulation for Arthritis Pain. Want an alternative to pain relievers? Try giving your nerves a little jolt.. ...
Most stimulation techniques work because of the brains predominantly electrical nature. That is, when a brain cell, or neuron ... What is electrical brain stimulation used for? And is it safe?. By Amanda Schaffer ... For many of us, the mere phrase "electrical brain stimulation" calls to mind highly disturbing images of electroshock therapy, ... The brain stimulation techniques now being researched are, by contrast, generally quite mild. DC polarization, for instance, ...
A new study at UCLA has found that a brain stimulation patch, worn on the forehead while the patient sleeps, can significantly ...
You can view electric stimulation (e-stim) much the same as charging a car battery or priming a motor before it will start. ... You can view electric stimulation (e-stim) much the same as charging a car battery or priming a motor before it will start. ... Treating Incontinence with Electric Stimulation. Tasha MulliganHealth Professional. July 19, 2010. ... The artificial stimulation of the nerves connecting to the many muscles of your pelvic floor can work like adding oil to a ...
... is a pain treatment that uses low voltage electric current to scramble pain signals in your body. tens is typically done with a ... What is TENS (transcutaneous electrical nerve stimulation)?. ANSWER TENS, or transcutaneous electrical nerve stimulation, is a ... The Cochrane Collaboration: "Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain." ... The Cochrane Collaboration: "Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain." ...
This standard provides guidelines and definitions of therapeutic neurostimulation waveforms for development engineers and health care professionals.
Scientists stimulated volunteers brains with mild electric current while they learned new arithmetic operations based on made- ... Those who received this brain stimulation learned quicker -- and retained a performance edge six months later. ... Electrical Brain Stimulation Helps People Learn Math Faster. Studying and practicing math is so difficult and boring that very ... The new research goes a step farther by showing that electrical stimulation can also improve the ability to perform ...
... electrical stimulation patch may be just as effective as triptan medications for alleviating migraine. ... Electrical brain stimulation found to improve working memory Scientists use transcranial alternating current stimulation to ... A wireless patch that uses electrical stimulation to block pain signals to the brain may one day replace drugs for the ... One group received treatment with the electrical stimulation patch, known as Nerivio, while the other group received a sham ...
Scientists use transcranial alternating current stimulation to improve working memory. The findings may one day help patients ... The electrical stimulation was alternately applied in an unsynchronized fashion, in a synchronized fashion, or in quick bursts ... The new study, published in the journal eLife, reveals that applying weak electrical stimulation to the brain helped to ... However, the specificities of each individuals brain may be an obstacle in using this form of electrical stimulation as a ...
... you might be interested to learn about functional electrical stimulation (FES). This delivers a shock to your affected muscle. ... This movement triggers an electric shock, which causes greater movement of the hand. Electrical stimulation can be used on all ... The main drawback is how well you tolerate the sensation of electrical shock. An electrical stimulation session at a ... Functional Electrical Stimulation. Spasticity is muscle overactivity that occurs when communication between your brain and ...
Emerging research suggests electrical stimulation of certain regions in the brain releases an opiate-like substance that can ... Electrical Brain Stimulation Activates Bodys Opiates. By Rick Nauert PhD Associate News Editor ... Emerging research suggests electrical stimulation of certain regions in the brain releases an opiate-like substance that can ... Investigators also say that the next step will investigate long-term effects of electric stimulation on the brain and find ...
It is thought that electrical stimulation of nerves via the skin may cause chemical changes in the brain. Learn more about this ... What is transcutaneous electrical nerve stimulation?. Transcutaneous electrical nerve stimulation, which is commonly known as ... It is thought that electrical stimulation of nerves via the skin may cause chemical changes in the brain. Learn more about this ... For details of pain professionals who use transcutaneous electrical nerve stimulation (TENS), contact this representative body ...
In the study, UK scientists discovered that when electrical ... New research suggests brain stimulation can be used to improve ... Electrical Brain Stimulation Can Improve Creativity. By Rick Nauert PhD Associate News Editor ... In the study, UK scientists discovered that when electrical stimulation suppressed a key part of the frontal brain, problem- ... The participants whose DLPFC was temporarily suppressed by the electrical stimulation were more likely to solve hard problems ...
electric brain stimulation. Update: A Fresh Look at Enhancing Brain & Mental Health Across the Lifespan. May 30, 2013. by ... electric brain stimulation, Kirkus Review, mental-exercise, Mental-Health, mental-training, neurocognitive, neuroplasticity, ... Cog-ni-tive enhance-ment in the future: elec-tric brain stim-u-la-tion plus cog-ni-tive training? ...
Next, researchers will investigate long-term effects of electric stimulation on the brain and find specific targets in the ... Electric stimulation of brain releases powerful, opiate-like painkiller. University of Michigan ... This suggests that repetitive electrical stimulation over several sessions are required to have a lasting effect on clinical ... The stimulation is called transcranial direct current stimulation (tDCS). The radiotracer was specifically designed to measure ...
... is a therapy that provides short-term pain relief using low-voltage electric current. It is noninvasive, inexpensive and can ... Transcutaneous Electrical Nerve Stimulation. Transcutaneous electrical nerve stimulation (TENS) is a technology that uses a ... What are the side effects of transcutaneous electrical nerve stimulation?. *Is transcutaneous electrical nerve stimulation safe ... What are the side effects of transcutaneous electrical nerve stimulation?. *Is transcutaneous electrical nerve stimulation safe ...
An electrical stimulation heat/cool pack includes a nonconductive pouch and straps for positioning and holding the ... Muscle- and nerve stimulation system has transcutaneous electrical nerve stimulation- electro muscle stimulation device with ... The present invention is directed to an electrical stimulation heat/cold pack in which the electrical distribution portion of ... Electrical stimulation electrode. US4887614 *. Apr 18, 1989. Dec 19, 1989. Kureha Kagaku Kogyo Kabushiki Kaisha. Medical ...
The effect on the urethra of intravaginal electrical stimulation (IVS) was registered by means of urethral pressure profiles ( ... UPP). With the object of finding the most appropriate electrical parame... ... Electrical stimulation was given via an obturator with seven electrodes, which could be connected in different combinations of ... The effect on the urethra of intravaginal electrical stimulation (IVS) was registered by means of urethral pressure profiles ( ...
Three different protocols of electrical stimulation, with 3 different electrical currents (AC, DC and pulsatile DC), were then ... in Frontiers in Bioengineering and Biotechnology researchers from SCERG-iBB and IT report on the electrical stimulation of ... Many cells in the human body respond to electrical stimuli. The differentiation of neural stem cells into mature neurons, in ... Three different protocols of electrical stimulation, with 3 different electrical currents (AC, DC and pulsatile DC), were then ...
Submission: Brain Power Boosted With Electrical Stimulation. DARPA Investing In Electric Brain Stimulation To Train Snipers ... Brain Power Boosted With Electrical Stimulation 153 Posted by samzenpus on Thursday September 22, 2011 @12:19AM. from the power ... I know that exercise helps brain function but shocking somebody in the head with an electrical probe isnt a very nice way to ... Brain Power Boosted With Electrical Stimulation More Login Brain Power Boosted With Electrical Stimulation. Archived Discussion ...
Electric Stimulation of Ammonotrophic Methanogenesis. Michael Siegert1* and Allen Tan2 ... Citation: Siegert M and Tan A (2019) Electric Stimulation of Ammonotrophic Methanogenesis. Front. Energy Res. 7:17. doi: ... Electrical current across the circuits increased with each batch cycle, even though the anodic potential was reduced (Figure S1 ... Keywords: bio-electrical system, anaerobic ammonium oxidation, microbial electrolysis cell, power-to-gas, biogas upgrading, ...
This topic has 4 study abstracts on Electric Stimulation indicating that it may have therapeutic value in the treatment of ... 8 Abstracts with Electric Stimulation Research. Filter by Study Type. Human Study. ... Acupuncture combined with electric stimulation achieves the much better efficacy on dysphagia after acute stroke and promotes ... Therapeutic Actions : Acupuncture, Electric Stimulation , Integrative Medicine. Additional Keywords : Significant Treatment ...
... , Electrical Muscle Stimulation, Transcutaneous electrical nerve stimulation, TENS, E-Stim. ... Electrical Stimulation Therapy. Electrical Stimulation Therapy Aka: Electrical Stimulation Therapy, Electrical Muscle ... These images are a random sampling from a Bing search on the term "Electrical Stimulation Therapy." Click on the image (or ... Electrical Muscle Stimulation. *Relief of muscle spasm or Muscle Strengthening (via isometric contraction) ...
Optimizing the Electrical Stimulation of Retinal Ganglion Cells A.E. Hadjinicolaou, C. O. Savage, N. V. Apollo, D.J. Garrett, S ... Abstract Neuromuscular electrical stimulation (NMES) has previously been used to enhance venous return from the lower leg. By ... Electrical stimulation (ES) of the sacral anterior roots with an implantable neuroprosthesis is one means to restore continence ... Fine-Wire Electromyography Response to Neuromuscular Electrical Stimulation in the Triceps Surae Paul P. Breen, Anand V Nene, ...
The Health Ministry issued a warning to the public on Monday on the use of EMS (electric muscle stimulation) equipment in gyms ... Non-medical use of electric muscle stimulation is dangerous - ministry. Elite athletes use EMS in addition to their training ... Our muscles contract through electric impulses (bioelectronics) in normal state. The EMS training makes use of this effect. By ... stimulation of metabolism and tightening of connective tissue.". ...
Scientists at the Dream and Nightmare Laboratory in Montreal test claims that applying electrical stimulation to the brain can ... Can Electrical Brain Stimulation Induce Lucid Dreams?. New study casts doubt on claims that brain stimulation augments lucid ... One study published in 2014 found that applying electrical stimulation to the brain could increase lucidity. Naturally during ... the results of the study were based on recordings of 27 naps with tAC stimulation, and 23 naps without stimulation. ...
Electrical stimulation of brain enables lucid dreaming, new study finds. Electrical stimulation of brain alters dreams: study ... Scientists said they had used a harmless electrical current to modify sleep so that an individual has lucid dreams, a ... The study, reported in the journal Nature Neuroscience, found that a harmless electrical current could bring on lucid dreaming ... However, brain stimulation should always be carefully monitored by a physician, she cautioned. ...
Subconvulsive Electrical Stimulation in Treatment of Chronic Neurosis Br Med J 1952; 2 :1170 ... Subconvulsive Electrical Stimulation in Treatment of Chronic Neurosis. Br Med J 1952; 2 doi: ...
Applying an electric current to the brain can help recovery from stroke, Oxford University researchers have found. Their ... The stimulation] didnt hurt - more like a mild tingle or a static electric shock right on the top of my head. The worst part ... Electrical brain stimulation could support stroke recovery. HealthScienceResearchStrokeNeuroscience ... Obsessing over electric cars is impeding the race to net zero: More active travel is essential 14 Jun 2021. ...
  • Another, called TMS, or transcranial magnetic stimulation , similarly influences brain circuitry and has been an area of active research since the early 1990s. (
  • In the 2010 study, Cohen Kadosh and colleagues used transcranial direct current stimulation (tDCS), which delivers a weak but constant current to the brain via electrodes placed on the skull. (
  • In the new study, they used transcranial random noise stimulation (TRNS): current that fluctuates randomly within certain bounds. (
  • Violante and team used a noninvasive technique called transcranial alternating current stimulation (TACS) to interfere with the brain's rhythm. (
  • The stimulation is called transcranial direct current stimulation (tDCS). (
  • The researchers used a technique called transcranial direct current stimulation (tDCS), which involved passing a weak constant electrical current through saline-soaked electrodes positioned over the scalp to modulate the excitability of the DLPFC. (
  • Transcranial magnetotherapy (TcMT) and electric stimulation (ES) improve erectile dysfunction in obese patients. (
  • Specifically, experimenters applied "transcranial Alternating Current" or "tAC" stimulation at 40 Hz (40 cycles per second) to the frontal region of the scalp, and found that it increased self-awareness in dreams. (
  • Researchers led by Ursula Voss at the J.W. Goethe University Frankfurt, used a technique called transcranial alternating current stimulation (tACS) to explore the causes of lucid dreaming. (
  • A team from Oxford's Nuffield Department of Clinical Neurosciences, led by Professor Heidi Johansen-Berg and Dr Charlotte Stagg, studied the use of transcranial direct current stimulation (tDCS) to support rehabilitation training. (
  • Some patients received Transcranial Direct Current Stimulation (tDCS) like this. (
  • On the first visit, patients were all given sham transcranial direct current stimulation (tDCS), a method in which low-amplitude current is sent to the brain through electrodes stuck to the scalp-in the sham version, patients are hooked up to the machine but no electricity comes out. (
  • To attempt to modify the DLPFC, researchers used a method called transcranial direct current stimulation (tDCS). (
  • IASIS is among a class of passive neurofeedback treatments that combine low-intensity pulses for transcranial electrical stimulation (LIP-tES) with electroencephalography (EEG) monitoring. (
  • Comparison of descending volleys evoked by transcranial magnetic and electric stimulation in conscious humans. (
  • The present experiments were designed to compare the understanding of the transcranial electric and magnetic stimulation of the human motorcortex. (
  • The spinal volleys evoked by single transcranial magnetic or electric stimulation over the cerebral motor cortex were recorded from a bipolar electrode inserted into the cervical epidural space of two conscious human subjects. (
  • Using surface electrodes, the researchers applied anodal transcranial direct current stimulation to the primary motor cortex, which controls movement. (
  • The persistence of a beneficial effect of anodal transcranial direct current stimulation at three months after the end of training may have promising implications for the design of motor learning protocols in healthy individuals and in patients undergoing neurorehabilitation," the researchers concluded. (
  • Transcranial Stimulation for the Inhibition of Primitive Reflexes in children with cerebral palsy. (
  • The electrical stimulation is called transcranial direct current stimulation (tDCS), a non-invasive therapy that delivers a small electrical current through electrodes placed on the head and along the spine. (
  • It is a central part of a larger project headed by Associate Professor Axel Thielscher that aims to improve Transcranial Direct Current Stimulation (TDCS) of the human brain by means of accurate computational dose control. (
  • The knowledge gained in your work will provide key insight for the verification and calibration of the forward models for transcranial brain stimulation, but also for EEG and MEG. (
  • You will join the Neurophysics group headed by Axel Thielscher that develops advanced biophysical methods to improve transcranial brain stimulation. (
  • The researchers wanted to test whether a treatment that sends a very weak electrical current through the skull to the outer layers of the brain, so-called transcranial direct current stimulation (tDCS), can actually make us smarter. (
  • TENS, or transcutaneous electrical nerve stimulation, is a pain treatment that uses low voltage electric current to scramble pain signals in your body. (
  • The electrodes carry an electric current from the TENS machine to the skin. (
  • The Cochrane Collaboration: "Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain. (
  • The Ohio State University Medical Center: "TENS (Transcutaneous Electrical Nerve Stimulation). (
  • Transcutaneous electrical nerve stimulation, which is commonly known as TENS, involves applying a mild electrical current through electrodes stuck to the skin. (
  • TENS (transcutaneous electrical nerve stimulation) delivers current to sore muscles, reducing pain for many. (
  • Transcutaneous electrical nerve stimulation (TENS) is a therapy that provides short-term pain relief using low-voltage electric current. (
  • The TENS device delivers electrical impulses through the skin to the nerves. (
  • The TENS unit is a small battery-operated device that delivers low voltage electric pulses. (
  • Aetna considers transcutaneous electrical nerve stimulators (TENS) medically necessary durable medical equipment (DME) when used as an adjunct or as an alternative to the use of drugs either in the treatment of acute post-operative pain in the first 30 days after surgery, or for certain types of chronic, intractable pain not adequately responsive to other methods of treatment including, as appropriate, physical therapy and pharmacotherapy. (
  • If the TENS unit produces incomplete relief, further evaluation with percutaneous electrical nerve stimulation (PENS) may be indicated. (
  • You can set the TENS machine for different wavelength frequencies, such as a steady flow of electrical current or a burst of electrical current, and for intensity of electrical current. (
  • Transcutaneous electrical nerve stimulation (TENS) therapy involves the use of low-voltage electric currents to treat pain. (
  • Transcutaneous electrical nerve stimulation (TENS) is a therapy that uses low voltage electrical current to provide pain relief. (
  • A TENS unit consists of a battery-powered device that delivers electrical impulses through electrodes placed on the surface of your skin. (
  • There are two theories about how transcutaneous electrical nerve stimulation (TENS) works. (
  • What is transcutaneous electrical nerve stimulation (TENS) therapy used to treat? (
  • For what types of conditions and areas of the body should transcutaneous electrical nerve stimulation (TENS) therapy not be used? (
  • Transcutaneous electrical nerve stimulation (TENS) for chronic pain ‐ an overview of Cochrane Reviews. (
  • Transcutaneous electrical nerve stimulation (TENS) has therapeutic activity in neurogenic bladder. (
  • We used transcutaneous electrical nerve stimulation (TENS) to induce referred sensations to the phantom hand of amputees. (
  • To help determine if neural pain pathways are affected by roller massage, transcutaneous electrical nerve stimulation (TENS) was utilized as a form of electroanalgesia during RM with PPT and ROM tested on the affected and contralateral quadriceps. (
  • a lead wire electrically connected to the flexible nerve and muscle stimulation electrode. (
  • 2. The electrical stimulation body pack according to claim 1 wherein both pouch surfaces include a loop material and said flexible electrical stimulation electrode comprises hook means for providing placement of the electrode at various positions on both pouch surfaces. (
  • electrically conductive gel means for releasably coupling the flexible electrical nerve and muscle stimulation electrode to said body part, said electrically conductive gel means being removable from said flexible pouch. (
  • 6. The electrical stimulation body pack according to claim 3 comprising a plurality of flexible electrodes attached to said pouch in a spaced apart array with each electrode having a separate lead wire attached thereto. (
  • 7. The electrical stimulation body pack according to claim 3 wherein the pouch and the flexible electrode attached thereto are washable. (
  • With the object of finding the most appropriate electrical parameters and optimal electrode positions within the vagina, 24 patients with stress incontinence, 22 with urgency and 4 continent women were studied. (
  • A flexible transcutaneous electrical nerve and/or muscle stimulation electrode is provided which utilizes a conductive material, preferably a conductive fabric, and electrical shunt means disposed along the conductive material for causing more uniform resistivity between any two equally spaced apart. (
  • 2. The flexible stimulation electrode according to claim 1 wherein said conductive fabric comprises a knit of conductive fibers having a higher resistivity along a longitudinal direction of knit than along a transverse direction of knit. (
  • 3. The flexible stimulation electrode according to claim 2 wherein the resistivity along the longitudinal direction of knit is up to about 20 times the resistivity along the transverse direction of knit. (
  • 4. The flexible stimulation electrode according to claim 1 wherein said electrical shunt means includes a plurality of strands disposed in a vein-like manner having a dichotomous venation. (
  • 8. The flexible stimulation electrode according to claims 4, 5, 6 or 7 wherein said electrical shunt means is disposed on an opposite side of said conductive fabric and is held against said opposite side in an electrically conductive manner by the flexible solid conductive adhesive disposed in said interstitial area. (
  • 9. The flexible stimulation electrode according to claim 8 wherein said electrode shunt means comprises a plurality of strands of stainless steel wire having a diameter of about 8 microns. (
  • A , Schematic of 4 electrode configurations used for electric field stimulation. (
  • We present an effective method for tailoring the flexibility of a commercial thin-film polymer electrode array for intracochlear electrical stimulation. (
  • determine, without user intervention, an electrical stimulation contribution of the at least one defined electrode to the at least one stimulation zone. (
  • generate, without user intervention, an electrical stimulation amplitude to be delivered by the at least one defined electrode based on the determined electrical stimulation contribution of the at least one defined electrode and a defined intensity. (
  • modify, without user intervention, the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the IMD in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching. (
  • 6. The method of claim 1 , wherein the electrical stimulation device includes at least one electrode and a flexible member that at least partially encapsulates the at least partially bendable housing, and wherein the at least one electrode protrudes through the flexible member. (
  • Subcutaneous Ports for Chronic Nerve Cuff and Intramuscular Electrode Stimulation in Animal Models. (
  • Single neuron responses in the inferior colliculus (IC), the main nucleus of the auditory midbrain, were studied using electric stimulation of bilaterally implanted intracochlear electrode arrays. (
  • It is administered by passing an electrical current through an electrode implanted in the brain. (
  • An electrode is implanted into the thalamus (part of the brain) of the patient and is attached to an electric pulse generator via an extension wire. (
  • The pulse generator sends out intermittent electrical stimulation to the electrode in the thalamus, which inhibits or partially relieves the tremor. (
  • 4. The system of claim 1 , wherein the waveform generator is configured to generate a stimulation waveform that includes the stimulation pulse and a secondary pulse, the secondary pulse to reduce accumulation of charge at an electrode that has delivered the stimulation pulse. (
  • The overarching aim in this project is to leverage our recently developed MREIT methods and FEM models of the TDCS-induced electric fields ( to quantify the physical stimulation strength of TDCS in the brain at the individual level. (
  • We aim to use this knowledge to assess dose-response relationships for TDCS in order to optimize the physiological stimulation outcome. (
  • Mild current stimulation (tDCS) had completely overloaded a brain region crucial to performing the task, as though it crashed it. (
  • Eleven study participants were all undergoing deep brain stimulation (DBS) treatment for Parkinson's disease. (
  • The lead may be useful in a variety of applications such as spinal cord stimulation to alleviate chronic pain, gastrointestinal stimulation to alleviate gastroparesis or obesity, pelvic floor stimulation to alleviate incontinence or sexual dysfunction, or deep brain stimulation to alleviate neurological disorders. (
  • This article analyses, on the basis of the pathophysiological grounds of various syndromes treated with deep brain stimulation, whether there is a collective explanation of the mode of action of the applied regional stimulations with high frequencies (HFS). (
  • Montgomery, E.B. and Baker, K.B. (2000) Mechanisms of deep brain stimulation and future technical developments. (
  • Dostrovsky, J.O. and Lozano, A.M. (2002) Mechanisms of deep brain stimulation. (
  • Electrical stimulation of the brain, or deep brain stimulation, is effective in treating tremors in up to 88 per cent of Parkinson's disease patients. (
  • Gastric electrical stimulation, also known as implantable gastric stimulation, is the use of specific devices to provide electrical stimulation to the stomach to try to bring about weight loss in those who are overweight or improve gastroparesis. (
  • Originally developed as a nonpharmacologic alternative for treatment of gastroparesis, gastric stimulation has been evaluated as a weight-loss aid and most recently as an option for patients with diabetes unresponsive to drug therapy. (
  • The study used a watch-sized digital microstimulator that was specially developed for this project to assess the effects of ongoing electrical stimulation at acupuncture points on gastroparesis symptoms in diabetic patients with refractory gastroparesis. (
  • The aims were to investigate the plasticity of the myosin heavy chain (MHC) phenotype following neuromuscular electrical stimulation (NMES) and to assess the correlation between MHC isoform distribution and muscle fibre conduction velocity (MFCV).14 men were subjected to 24 sessions of quadriceps NMES. (
  • Neuromuscular electrical stimulation (NMES) can be used in swallowing therapy. (
  • A Comparison of Neuromuscular Electrical Stimulation Parameters for Postoperative Quadriceps Strength in Patients After Knee Surgery: A Systematic Review. (
  • This unit provides neuromuscular electrical stimulation. (
  • Neuromuscular electrical stimulation may be an alternative strategy to reverse muscle weakness. (
  • The objective of the study was to review the scientific publications on the use of neuromuscular electrical stimulation and its parameters and the main results in patients hospitalized in intensive care units. (
  • The studies were selected from the following descriptors: neuromuscular electrical stimulation AND parameters AND intensive care units AND muscle weakness. (
  • The inclusion criteria included articles that addressed the topic of neuromuscular electrical stimulation and the parameters used in patients admitted to intensive care units, aged 18 years or older. (
  • The parameters of the neuromuscular electrical stimulation employed in the studies showed positive results for the maintenance of strength and muscle mass. (
  • Since a large proportion of critical patients cannot participate in any active mobilization, neuromuscular electrical stimulation (NMES) may be an alternative strategy for muscle training [13]. (
  • Stimulation parameters are most often empiric and not based on systematic studies. (
  • Manual needling is the classic method, and electro-acupuncture (EA), that is, electrical stimulation is introduced to the body via metallic needles inserted into the acupoints is the most commonly used modality today [ 16 ], which has a characteristic feature of highly reproducible stimulation parameters, and great savings in manpower. (
  • The crucial stimulus parameters were biphasic symmetric square wave at 50 pulses per second, phase duration of 300 microseconds, a starting ramp uptime of 2 seconds and a finishing ramp downtime of 2 seconds per stimulation cycle, and a stimulation cycle of 12 seconds "on" and 48 seconds "off" per minute. (
  • 14. The stimulator of claim 8 , wherein parameters of the electrical stimulation pulses are selected to alleviate symptoms of one or more of chronic pain, a gastrointestinal disorder, a urinary tract disorder, or sexual dysfunction. (
  • Various programming techniques are described for medical devices that deliver electrical stimulation therapy that may include mapping between discrete electrical stimulation parameters and a graphical view of the electrical stimulation representing a stimulation zone generated by the parameters. (
  • Depending on the type of injury sustained, there are various electrical stimulation parameters. (
  • Stimulation parameters were explored in an effort to find stimuli that might result in the best ITD sensitivity for clinical use. (
  • 8. The system of claim 1 , further comprising a converter configured to convert the stored charge setting value into one or more stimulation parameters characterizing aspects of the stimulation pulse that is to be delivered to the tissue, wherein the waveform generator is configured to generate the stimulation pulse in accordance with the stimulation parameters. (
  • 10. The system of claim 8 , further comprising a data compilation storing predetermined charge setting values and corresponding predetermined stimulation pulse durations and amplitudes, wherein the converter is configured to access the data compilation to convert the stored charge setting value into the one or more stimulation parameters. (
  • What are the types of transcutaneous electrical nerve stimulation? (
  • The purpose of this study was to determine whether some types of transcutaneous electrical nerve stimulation cause local vasodilation. (
  • It sends an electric current to your nerves to override pain signals. (
  • NMES applies electrical impulses to nerves to make the muscles contract. (
  • The artificial stimulation of the nerves connecting to the many muscles of your pelvic floor can work like adding oil to a motor. (
  • When instructed by the app, the device generates electrical pulses, which stimulate sensory nerves under the skin. (
  • One possible treatment is functional electrical stimulation, which delivers a shock to your affected muscle, activating nerves and making the muscle move. (
  • It is thought that electrical stimulation of nerves via the skin may cause chemical changes in the brain. (
  • Another theory is that the electrical stimulation of the nerves may help the body to produce natural painkillers called endorphins, which may block the perception of pain. (
  • In either, a small pulse generator sends electrical pulses to the nerves (in peripheral nerve stimulation) or to the spinal cord (in spinal cord stimulation). (
  • It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain. (
  • People who received brain stimulation during training sessions on five consecutive days learned two to five times faster than those who received sham stimulation, and they retained a 30 to 40 percent performance edge six months later. (
  • Compared to subjects who got sham stimulation, those who received TRNS also learned more quickly to do calculations with novel operands (the symbols like + and - that tell you what to do with the numbers on either side, but in this case the new symbols required somewhat more complicated operations). (
  • One group received treatment with the electrical stimulation patch, known as Nerivio , while the other group received a sham stimulation treatment. (
  • Shortly after the start of a migraine, each participant was instructed to apply the Nerivio patch or the sham stimulation device to their upper arm. (
  • The researchers found that at the three highest levels of stimulation, 64 percent of individuals treated with the Nerivio patch reported a reduction in migraine pain by more than 50 percent in the 2 hours after treatment, compared with just 26 percent of subjects who received the sham treatment. (
  • Additionally, the team found that at the very highest stimulation level, 58 percent of people who started out with moderate to severe migraine said that their pain was mild or had disappeared following Nerivio treatment, compared with only 24 percent of those in the sham treatment group. (
  • To find out whether the stimulation would improve performance over time, the researchers recruited 24 healthy volunteers and assigned half to active stimulation and half to sham stimulation while performing a task. (
  • One group received electrical stimulation of the brain and spinal cord five days a week for two weeks while the other group received a sham stimulation where the electrodes were placed on the participant, but the electric current was powered down after five seconds. (
  • When the participants received the stimulation treatment, they improved in every test, while when they received the sham stimulation, they showed no improvement on any test. (
  • After the sham stimulation, the participants had no changes in their times to complete the test. (
  • One month after receiving the stimulation, participants took an average of 47 seconds to complete the test, while after the sham stimulation they had no change in their speed. (
  • In TMS, researchers position an electromagnetic coil shaped like a figure eight above the patient's head and, in an interplay of electric and magnetic phenomena, current running through the coil creates brief but strong magnetic pulses, which pass through the cranium and enter the brain. (
  • There, these pulses can induce electrical changes in particular neurons-either increasing or diminishing activity, depending on certain features of the original electrical signal. (
  • In FES, small electrical pulses are applied to paralyzed muscles to stimulate movement. (
  • Physiological and Therapeutic Effects of High Frequency Electrical Pulses. (
  • These results show that bilateral electric stimulation can produce normal ITD tuning in IC neurons and suggest that the interaural timing of current pulses should be accurately controlled if one hopes to design a bilateral cochlear implant processing strategy that provides salient ITD cues. (
  • The National MS Society frequently fields questions about functional electrical stimulation (FES) - usually in relation to the products WalkAide from Innovative Neurotronics, NESS L300™ from Bioness® and the Odstock Dropped Foot Stimulator from Odstock Medical Limited in the United Kingdom. (
  • 11. The stimulator of claim 8 , wherein the stimulation electrodes include at least sixteen stimulation electrodes. (
  • Using electric anodal stimulation, at a stimulus intensity of 9% of the stimulator output above the active motor threshold (corresponding approximately to 1.5 active motor threshold), a small I1 wave appeared only in subject 1. (
  • Using magnetic stimulation with a posterior-anterior induced current, at a stimulus intensity of 21% of maximum stimulator output above the active motor threshold (corresponding approximately to 1.8 times threshold in subject 1 and to two times threshold in subject 2), a small D wave appeared in subject 1 but not in subject 2. (
  • In one example, a method includes receiving, via a programmer for an electrical stimulator, user input that graphically manipulates at least one of size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer, and defining a program to control delivery of electrical stimulation therapy based on the user input. (
  • That's exactly what the BionicGym, an advanced wearable neuro-stimulator, claim to help you achieve by delivering sophisticated electric pulse patterns to your muscles. (
  • In an experiment that sounds just slightly like science fiction, researchers at the National Institutes of Health found that by running a small electrical current through the front of the brain, they could markedly improve a person's verbal agility. (
  • After the volunteers had plunged into REM sleep, a state in which people are unable to move and the most vividly recalled dreams occur, researchers applied electrical current to their skulls near the forehead and temples. (
  • Researchers suggest that migraine could be treated with a wireless, electrical stimulation device. (
  • Queen Mary University of London (QMUL) and Goldsmiths University of London researchers used electrical stimulation to temporarily suppress the left dorsolateral prefrontal cortex (DLPFC). (
  • Next, researchers will investigate long-term effects of electric stimulation on the brain and find specific targets in the brain that may be more effective depending on the pain condition and patients' status. (
  • In a recent publication in Frontiers in Bioengineering and Biotechnology researchers from SCERG-iBB and IT report on the electrical stimulation of neural stem cells on electroconductive platforms made of conjugated polymer PEDOT:PSS. (
  • So, researchers decided to apply fast electrical currents to the scalp, to modulate underlying brain activity toward a desired frequency. (
  • Researchers at the Dream and Nightmare Laboratory in Montreal recently conducted a similar study to test whether applying 40 Hz tAC stimulation to the frontal brain region during REM sleep increases the occurrence of lucid dreams. (
  • Applying an electric current to the brain can help recovery from stroke, Oxford University researchers have found. (
  • While each monkey practiced the new skill, researchers "listened in" on the distinct patterns of electrical messages passing among the cells of his visual cortex. (
  • What happened when the researchers "played back" those electrical patterns was remarkable: When a monkey's visual neurons were electrically stimulated with the "sight" of a circle, his eyes immediately went to it -- even when it was not really on the screen in front of him. (
  • The images created by electrical stimulation to the brain proved to be pretty "washed out," the researchers reported. (
  • By strengthening the power of the electrical current, the study suggested to researchers they could improve visual acuity. (
  • Electrical impulses sent to a paralyzed man's spinal cord allow him to walk again, researchers say. (
  • Researchers suggest that the stimulation may have altered learning by biasing individuals to repeat physical actions that resulted in reward. (
  • Some researchers have reported that more than half of people receiving spinal cord stimulation for chronic low back and leg pain, ischemic leg pain (for example, from peripheral arterial disease ), or complex regional pain syndrome have pain reduction or relief. (
  • BETHESDA, Md., Jan. 20 -- Noninvasive electrical stimulation of the brain may improve the ability to learn a motor task, a finding with possible implications for treating patients with brain injuries, researchers suggested. (
  • therefore, participants who received the stimulation remained significantly more skillful ( P =0.005), the researchers reported online in the Proceedings of the National Academy of Sciences . (
  • The difference between the groups in learning between sessions was likely responsible for the overall difference in learning, the researchers said, and likely resulted from improvements in consolidation in the stimulation group. (
  • When stimulation was delivered to the right place at the right time, the researchers found, it could improve memory performance among the patients by as much as 50 percent. (
  • Now researchers at MIT have developed a fiber that is very elastic, while accurately transmitting both a light signal through its core or an electric one through its exterior. (
  • The researchers successfully used the new fibers in freely moving mice, showing that they are able to both read the electrical signals from the spinal cord, as well as stimulate it using both electricity and light. (
  • Electrical stimulation of the brain's cells while solving challenging tasks can lead to mental overload far from making you smarter, warn researchers. (
  • The researchers found no effect of stimulation when participants performed the simple and medium tasks, yet they found a large negative effect on the most difficult tasks. (
  • While this may be of interest to sleep researchers, Voss's work is reaching a wider audience since she and Professor J Allan Hobson of Harvard applied electrical stimulation to 27 participants hoping to replicate the same mixture of brainwaves. (
  • Voss and Hobson waited until their subjects were showing the signs of REM sleep to apply stimulation to the scalp at various frequencies double blinded from researchers and sleepers alike. (
  • Gastric electrical stimulation is a pacemaker-like device with electrical connections to the surface of the stomach. (
  • electrical stimulation of the skin to relieve pain by interfering with the neural transmission of signals from underlying pain receptors … a physical therapist can show you exercises to maintain strength and movement in the affected area and may also use transcutaneous electrical nerve stimulation , in which a small device transmits electrical impulses that stimulate nerve endings and relieve pain. (
  • The 34 patients in the study lost about 10 pounds and two inches from their waistline during a six-month evaluation of the device, which discharged electrical current into the gastric antrum. (
  • The device senses food intake and transmits electrical current to the stomach to stimulate gastric contraction. (
  • A method and device for controlling autonomic or sympathic nerve stimulation of the gastrointestinal tract. (
  • The device may be a neurostimulation device having a miniaturized housing with a low profile that permits subcutaneous implantation at a stimulation site directly adjacent a neuralgic region at the back of the neck of a patient. (
  • 2. The method of claim 1 , further comprising implanting the electrical stimulation device in the subcutaneous region within the back of the neck of the patient. (
  • 8. The method of claim 1 , wherein the at least partially bendable housing defines a hole, and wherein a suture is placed through the hole to anchor the electrical stimulation device at a stimulation site in the subcutaneous region. (
  • 9. The method of claim 1 , wherein the electrical stimulation device include a plurality of electrodes arranged in a two-dimensional array on a surface of the housing. (
  • The device is an implant that provides electrical stimulation to the lower esophageal sphincter (LES) muscle. (
  • This market report offers a comprehensive analysis of the global Respiratory Electrical Stimulation Device market . (
  • This report focused on Respiratory Electrical Stimulation Device market past and present growth globally. (
  • A detailed overview of key market drivers, trends, restraints and analyzes the way they affect the Respiratory Electrical Stimulation Device market in a positive as well as the negative aspect. (
  • In this report, the United States Respiratory Electrical Stimulation Device market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (
  • Production Analysis - Production of the Respiratory Electrical Stimulation Device is analysed with respect to different regions, types and applications. (
  • Here, price analysis of various Respiratory Electrical Stimulation Device Market key players is also covered. (
  • Sales and Revenue Analysis - Both, sales and revenue are studied for the different regions of the global Respiratory Electrical Stimulation Device Market. (
  • Supply and Consumption - In continuation with sales, this section studies supply and consumption for the Respiratory Electrical Stimulation Device Market. (
  • Competitors - In this section, various Respiratory Electrical Stimulation Device industry leading players are studied with respect to their company profile, product portfolio, capacity, price, cost and revenue. (
  • Other analyses - Apart from the aforementioned information, trade and distribution analysis for the Respiratory Electrical Stimulation Device Market, contact information of major manufacturers, suppliers and key consumers is also given. (
  • The report talks about the market dynamics - the trends that are shaping the global Respiratory Electrical Stimulation Device market. (
  • An electric brain stimulation tremor-control device used in treating people suffering from Parkinson's may interfere with or be affected by cardiac pacemakers and other medical equipment. (
  • Patients with an implanted electric brain stimulation tremor-control device may experience headaches, disequilibrium (disturbance of the sense of balance), burning or tingling of skin or partial paralysis. (
  • However, they involve sending electrical impulses though your body. (
  • The electric impulses might cause a prickling sensation that might be uncomfortable for some. (
  • Our muscles contract through electric impulses (bioelectronics) in normal state. (
  • They work by sending low-level electrical impulses to the peroneal (sometimes called fibular) nerve, which signals leg muscles to lift the foot. (
  • Neuroscientists implanted 16 electrodes in his spine, and sent electrical impulses to his lower spinal cord, mimicking the signals normally sent by the brain to initiate movement. (
  • The electrodes are often placed on the area of pain or at a pressure point, creating a circuit of electrical impulses that travels along nerve fibres. (
  • The new study, published in the journal eLife , reveals that applying weak electrical stimulation to the brain helped to harmonize different parts of the brain, improving the participants' memory. (
  • The participants whose DLPFC was temporarily suppressed by the electrical stimulation were more likely to solve hard problems than other participants whose DLPFC was activated or not stimulated. (
  • Participants were then awakened for dream reports after about 10 minutes of REM sleep (and at least 3 minutes after stimulation ended). (
  • After excluding participants who missed sessions, had inadequate REM sleep or no dream recall, the results of the study were based on recordings of 27 naps with tAC stimulation, and 23 naps without stimulation. (
  • In 5 of the 27 naps with stimulation, participants became lucid and successfully signaled with Left-Right eye movements. (
  • Furthermore, in 4 of the 23 naps without stimulation, participants became lucid and signaled with eye movements. (
  • When stimulation was provided in the substantia nigra following reward, participants tended to repeat the button press that resulted in a reward. (
  • Explain to interested patients that this study found a benefit for electrical stimulation of the brain in learning a complex motor task in healthy participants. (
  • Healthy participants who received a mild electric current applied to the primary motor cortex became more skillful at a complex motor task than those who did not receive the stimulation ( P =0.005), Leonardo Cohen, M.D., of the National Institute of Neurological Disorders and Stroke, and colleagues found. (
  • In between sessions, participants in the control group showed a significant decrease in learning ( P =0.05), and those in the stimulation group demonstrated a trend toward increased learning ( P =0.091). (
  • Participants performed a task inside an MRI scanner (see 'The Stop Signal Task' in notes to editors) while receiving small amounts of electrical current through electrodes on the surface of the scalp or a placebo. (
  • They found that healthy participants who received brain stimulation performed better in the task than when they didn't receive the treatment. (
  • Dr Li explains the team will now focus on larger studies with more participants to investigate what other factors influence someone's response to brain stimulation. (
  • Electrical stimulation is used in a controlled environment for no more than ten minutes at a time and only on participants who have passed strict medical checks. (
  • Spinal cord stimulation uses a wire that's surgically implanted under your skin to deliver an electrical current directly to your spinal cord. (
  • A 2014 literature review published in Pain Physician summarized that spinal cord stimulation can be effective for treating chronic pain of the torso and limbs, intractable low back pain , leg pain, and pain from failed back surgery. (
  • Peripheral nerve stimulation (PNS) and spinal cord stimulation (SCS) are two types of electrical nerve stimulation. (
  • A typical schedule for spinal cord stimulation is to use it for 1 or 2 hours, 3 or 4 times a day. (
  • There isn't a lot of evidence to show how well spinal cord stimulation works. (
  • footnote 1 Spinal cord stimulation may also help chronic low back pain. (
  • Leakage of spinal fluid during spinal cord stimulation. (
  • Bladder problems in spinal cord stimulation. (
  • 2004). Spinal cord stimulation for chronic pain. (
  • Transcutaneous Spinal Cord Stimulation Restores Hand and Arm Function After Spinal Cord Injury. (
  • Gastric electrical stimulation is contraindicated in patients who are not candidates for surgical procedures, anesthesia, or both, because of either physical or mental conditions. (
  • One study published in 2014 found that applying electrical stimulation to the brain could increase lucidity. (
  • London - Is it possible to boost creativity by applying electrical stimulation to the brain? (
  • Electrical stimulation was performed via surface ECG electrodes placed at acupoints PC6 and ST36 using pulse trains. (
  • Electrical foot stimulation (see Figure 1) was produced by surface electrodes placed on the sole of the foot over the plantar muscle group. (
  • Aetna considers electrical stimulation (electrical current via electrodes placed directly on the skin in close proximity to the ulcer) medically necessary durable medical equipment (DME) for the management of the following types of chronic ulcers when it is used as adjunctive therapy after there are no measurable signs of healing for at least 30 days of treatment with conventional wound treatments. (
  • There is some evidence that peripheral nerve stimulation helps certain types of chronic pain, such as peripheral nerve pain and pain after surgery. (
  • Electrical nerve stimulation may be recommended for some people who have certain types of chronic pain. (
  • Patients with chronic pain will sometimes use a portable electrical stimulation unit at home. (
  • Electrical stimulation of the brain is a relatively new technique used to treat chronic pain and tremors associated with Parkinson's disease. (
  • Most stimulation techniques work because of the brain's predominantly electrical nature. (
  • In TACS , alternating electrical current is applied through the skull to modify the brain's cortical oscillations. (
  • It showed that direct stimulation to the brain's visual cortex can create the perception of shapes, colors and contrasts -- even when the eyes cannot see them. (
  • instead, they have proposed to supply the electrical messages that the brain interprets as an "image" directly to the brain's visual cortex. (
  • Still, his doctors hope that someday, patients with spinal cord injuries could use a portable electrical stimulation unit to move independently once again. (
  • Electrical stimulation (ES) of the sacral anterior roots with an implantable neuroprosthesis is one means to restore continence. (
  • Explain to patients that two different types of implantable electrical stimulators improved diabetes control and induced weight loss. (
  • An implantable electrical lead may include a conformable array of electrodes. (
  • Intestinal electrical stimulation via implants is already used to treat several disorders like constipation or incontinence. (
  • Posted in Treatments & Management for Incontinence and tagged biofeedback , e-stim , electric stimulation , pelvic floor exercises , pelvic floor muscle exercises , prostate treatment , stress urinary incontinence . (
  • Transcutaneous electrical nerve stimulation use in children with incontinence refractory to pharmacotherapy is safe and well tolerated. (
  • A wireless patch that uses electrical stimulation to block pain signals to the brain may one day replace drugs for the treatment of migraine, a new study suggests. (
  • Different levels of stimulation were tested, and each treatment lasted around 20 minutes. (
  • In the future, the scientists hope to use this form of brain stimulation as a treatment for patients with traumatic brain injury . (
  • Non-invasive low strength pulsed electric field to EGCG treatment synergistically enhanced the inhibition effect on PANC-1 cells. (
  • Brain stimulation has emerged as an effective treatment for a wide range of neurological and psychiatric diseases. (
  • Functional electrical stimulation (FES) is a treatment that involves the application of a mild electrical stimulus to a muscle that helps it to move better. (
  • The primary objective of this clinical trial was to demonstrate the noninferiority of the experimental treatment (electrical foot stimulation) relative to standard accepted treatment (IPC). (
  • Continued electrical stimulation is not considered medically necessary if measurable signs of healing have not been demonstrated within a 4-week treatment period. (
  • Aetna considers electrical stimulation for the treatment of chronic ulcers in the home setting not medically appropriate. (
  • Aetna considers frequency rhythmic electrical modulation and wireless micro-current stimulation experimental and investigational for the treatment of chronic ulcers because their effectiveness for this indication has not been established. (
  • Aetna considers combined use of modulated ultrasound and electric current stimulation for the treatment of diabetic foot ulcers experimental and investigational because the effectiveness of this approach has not been established. (
  • Transcutaneous electrical nerve stimulation has therapeutic value in the treatment of trigeminal neuralgia. (
  • But Wes has also benefitted tremendously from a cutting-edge technology that is revolutionizing therapies for patients suffering from brain injuries and neurodegenerative diseases: a new treatment known as functional electrical stimulation (FES). (
  • This form of treatment, called electrical stimulation, is safe and effective but there are some important facts to know before seeking this treatment. (
  • The electrical stimulation chosen is based on which goal is being addressed during treatment. (
  • Electrical stimulation is a relatively safe treatment with very few adverse effects. (
  • Electrical stimulation is a very beneficial treatment but should only be provided by a trained expert. (
  • According to the team, the findings, published in the journal Brain, could help to personalise the non-invasive electrical brain stimulation, targeting the treatment to patients who are most likely to gain clinical benefits. (
  • The team cautions that while more work is needed to confirm the findings, it could mean brain stimulation might prove a useful treatment approach for other neurological conditions with abnormal brain activity as a feature, such as dementia. (
  • Application of electric current in treatment without the generation of perceptible heat. (
  • While implantation of electrodes in the brain is used to treat or diagnose several disorders, the term electric brain stimulation is limited to the treatment of tremors and as a pain-management tool for patients suffering from back problems and other chronic injuries and illnesses. (
  • Study finds long term lower extremity functional electrical stimulation (FES) cycling associated with substantial improvements in individuals with chronic spinal cord injury (SCI). (
  • Lower Extremity Functional Electrical Stimulation Cycling Promotes Physical & Neurological Recovery In Chronic Spinal Cord Injury - Study by Kennedy Krieger's International Center for Spinal Cord Injury suggests activity-based restorative therapy programs may provide substantial benefits for persons with chronic SCI. (
  • A new study by Kennedy Krieger Institute's International Center for Spinal Cord Injury finds that long-term lower extremity functional electrical stimulation (FES) cycling, as part of a rehabilitation regimen, is associated with substantial improvements in individuals with chronic spinal cord injury (SCI). (
  • Our research questions is: What are the differences in long term functional outcomes of patients that have ulnar nerve decompression surgery with and without nerve stimulation? (
  • Electrical Nerve Stimulation of the Ulnar Nerve During Cubital Tunnel Decompression Surgery: Does it Improve Long Term Functional Outcomes? (
  • Anodal stimulation has previously been shown to increase the learning of motor skills in healthy people. (
  • At active motor threshold intensity, the electric anodal stimulation evoked pure D activity. (
  • Learning how to translate complex visual images into electrical signals that convey the density of information a human expects -- not only the shapes and colors of objects but their distance from oneself -- will be an enormous task, Schiller added. (
  • The new technology provides a unique way to couple electric signals in the neural network to the magnetic dipoles in the nanoparticles with the purpose to enable a non-invasive approach. (
  • That means interruption of messages from the brain may not preclude paralyzed patients from walking again - they would just need new electrical signals to stimulate the spinal cord. (
  • One theory is that the electric current stimulates nerve cells that block the transmission of pain signals, modifying your perception of pain. (
  • Specifically, this invention is concerned with the muscle action of the small and large intestines and the production of enzymes and hormones by means of specifically coded electrical waveforms, which emulate the natural coded signals that normally control the gastrointestinal tract. (
  • Electrical stimulation controls pain by interfering with the pain signals at the spinal cord level. (
  • The control only works if it continuously receives electrical signals from the brain. (
  • Although the artificial stimulation of the neural pathways helps to open up the lines of communication, this won't translate into strength or endurance gains within the muscle fibers until you voluntarily contract your pelvic floor muscles along with the e-stim. (
  • Electrical stimulation is especially beneficial in individuals who can't contract their pelvic floor muscles on their own due to weak muscle control. (
  • However, the specificities of each individual's brain may be an obstacle in using this form of electrical stimulation as a widely accessible therapy. (
  • This form of electrical stimulation drives medication into the skin. (
  • Emerging research suggests electrical stimulation of certain regions in the brain releases an opiate-like substance that can reduce severe pain. (
  • New research suggests brain stimulation can be used to improve creativity in a paradoxical manner. (
  • There is no conclusive evidence, but some research suggests chronic electrical stimulation might damage the nerve structure and disturb its function. (
  • Preliminary research suggests that electrical stimulation can improve attention as well as have a positive impact on people with cognitive impairments and depression. (
  • This paper reviews applications of therapeutic electrical stimulation (ES) specific to wound healing and pressure sore prevention. (
  • Electrical brain stimulation is a form of electrotherapy and technique used in research and clinical neurobiology to stimulate a neuron or neural network in the brain through the direct or indirect excitation of its cell membrane by using an electric current. (
  • While we've suspected, based on previous studies in animal models, that these dopaminergic neurons in the substainia nigra - play an important role in reward learning, this is the first study to demonstrate in humans that electrical stimulation near these neurons can modify the learning process," said the study's co-senior author Gordon Baltuch, MD, PhD, professor of Neurosurgery in the Perelman School of Medicine at the University of Pennsylvania. (
  • Present results demonstrate that, in conscious humans at threshold intensities, electric stimulation evokes D waves and magnetic stimulation (with a posterior-anterior induced current) evokes I waves, while magnetic stimulation (with a latero-medial induced current) evokes both activities. (
  • Research has also highlighted that electrical brain stimulation could have favourable effects on humans, but some companies are selling such devices online, leading to calls to regulate the technology. (
  • Interventions like DC polarization and TMS appear to alter the electrical environment in a particular brain area, making it easier (or more difficult) for neurons in that region to fire. (
  • PHILADELPHIA - Stimulation of a certain population of neurons within the brain can alter the learning process, according to a team of neuroscientists and neurosurgeons at the University of Pennsylvania. (
  • A report in the Journal of Neuroscience describes for the first time that human learning can be modified by stimulation of dopamine-containing neurons in a deep brain structure known as the substantia nigra. (
  • Anderson, M.E., Postupna, N. and Ruffo, M. (2003) Effects of high-frequency stimulation in the internal globus pallidus on the activity of thalamic neurons in the awake monkey. (
  • Electric ITD tuning was often as sharp as that with acoustic stimulation in normal-hearing animals, but many neurons had dynamic ranges of ITD sensitivity limited to a few decibels. (
  • For many of us, the mere phrase "electrical brain stimulation" calls to mind highly disturbing images of electroshock therapy , or ECT, in which a very strong current is passed briefly through the brain, causing the patient to have a seizure. (
  • Scientists stimulated volunteers' brains with mild electric current while they learned new arithmetic operations based on made-up symbols. (
  • The study, reported in the journal Nature Neuroscience, found that a harmless electrical current could bring on 'lucid dreaming. (
  • Scientists said they had used a harmless electrical current to modify sleep so that an individual has 'lucid dreams,' a particularly powerful form of dreaming. (
  • When the circle generated by electrical current was brighter than the one on the screen, the monkey demonstrated he could discern the difference in brightness by moving his eyes to the brighter one, as he had been taught. (
  • Activated from morning until bedtime, the VBLOC, made by EnteroMedics, delivers preprogrammed electrical current on an intermittent basis. (
  • A study of stimulation current effects on wound healing in a pig model has shown that direct current (DC) stimulation is most effective in wound area reduction and alternating current (AC) stimulation for wound volume reduction at current densities of 127 microA/cm2 and 1,125 microA/cm2, respectively. (
  • Usually, you connect two electrodes (wires that conduct electrical current) from the machine to your skin. (
  • This process involves moving a weak constant electrical current through saline-soaked electrodes. (
  • At this intensity, magnetic stimulation with the induced current flowing in a posterior-anterior direction evoked pure I1 activity. (
  • When a latero-medial induced current was used, magnetic stimulation evoked both D and I1 activity. (
  • Transcutaneous electrical stimulation and interferential current are effective at addressing this pain. (
  • Stimulation at 3 times the sensory threshold produced local hyperthermia, which was maximal when a current of 100 pps was delivered through small electrodes. (
  • The technique, called non-invasive electrical brain stimulation, involves applying an electrical current to the surface of a patient's head to stimulate brain cells, altering the patient's brain activity. (
  • With all the current buzz around brain stimulation for altering brain activity, it's important to understand who will benefit most from this technique in the clinic. (
  • In this work, we demonstrated that cathodal direct current stimulation to the tongue inhibits salty and umami perception and investigated the relationship between magnitude of current and the effect size of the taste suppression. (
  • An electrical stimulation session at a rehabilitation center is billed like an ordinary physical therapy session and is reimbursable through Medicare. (
  • It is one of the most popular forms of electric therapy for pain relief. (
  • These images are a random sampling from a Bing search on the term "Electrical Stimulation Therapy. (
  • As a potential supplement to physical therapy, transcutaneous electric muscle stimulation (TEMS) is a non-invasive method directed at maintaining skeletal muscle function through artificially induced contractions that are independent of patient efforts. (
  • A course of electrical stimulation therapy for chronic cutaneous ulcers would not typically be expected to exceed 60 minutes per day, or a total duration of more than 4 weeks. (
  • Courses of electrical stimulation therapy for chronic cutaneous ulcers exceeding 1 hour per day are not considered medically necessary, as prolonged treatments beyond 1 hour per day have not been proven to offer additional clinically significant benefits. (
  • The effects of cerebral electric therapy (electrosleep) on anxiety, depression, and hostility in psychiatric patients. (
  • The Endostim LES Stimulation therapy showed a 77% normalization or 50% reduction of PPI use in one small group of patients and in another group of only 11 patients 91% were able to come off of medications ( 2 ). (
  • Electric Stimulation Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (
  • This graph shows the total number of publications written about "Electric Stimulation Therapy" by people in Harvard Catalyst Profiles by year, and whether "Electric Stimulation Therapy" was a major or minor topic of these publication. (
  • Below are the most recent publications written about "Electric Stimulation Therapy" by people in Profiles. (
  • Use of overnight pulse oximetry and a type 3 sleep study to titrate hypoglossal nerve stimulation therapy. (
  • citation needed] Electric stimulation of the auditory system via cochlear implant is a commonly used technique for individuals with a severe to profound sensorineural hearing loss, as well as for those adults and children with some residual hearing. (
  • These results are important because they show the potential of improving mental functions relevant for creativity by non-invasive brain stimulation methods," Luft said. (
  • Recent therapies that combine behavioral and brain stimulation methods may prove more promising, she said. (
  • That is, when a brain cell, or neuron, "fires," rapid electrical changes occur which allow the cell to signal its neighbors, often passing on a "message" of some kind-the impulse to move a muscle, for instance, or to respond to external stimuli. (
  • The Health Ministry issued a warning to the public on Monday on the use of EMS (electric muscle stimulation) equipment in gyms and at home for exercise and losing weight. (
  • Personal trainers, gyms and beauty centers concentrate on the fitness and beauty aspects - body shaping through muscle formation and catabolism of fat, stimulation of metabolism and tightening of connective tissue. (
  • The company claims the electric shock is supposed to relax your muscles, possibly make you lose weight and gain muscle. (
  • Individuals with very weak pelvic muscle control can still gain the benefits of pelvic floor exercises by using electric stimulation. (
  • The member requires electrical stimulation beneath a cast to treat disuse atrophy, where the nerve supply to the muscle is intact. (
  • To ensures baseline comparability, eliminates many of the inter-individual confounding factors often present in ICU patients and enhances statistical strength we designed a study where we included a well-defined group of patients with septic shock in a single-legged exercise design, using the contralateral leg as the (paired) control and used a two-channel stimulation approach with 3-D evaluation of muscle volume changes based on CT scans. (
  • Stimulation was increased to an intensity just sufficient to create a slight visible muscle twitch. (
  • The idea is that by using the electrical stimulation to make the muscle fire, his brain will retrain and relearn, and his muscles will fire more automatically without it in the long term," Jolene Hammer, a physical therapist at Lehigh Valley Hospital in Bethlehem, PA. (
  • What is the Effectiveness of Electric Muscle Stimulation on Injuries? (
  • Someone is receiving electrical muscle stimulation for their shoulder. (
  • How Does Electrical Muscle Stimulation Work? (
  • context":"http:\/\/","@type":"NewsArticle","headline":"What is the Effectiveness of Electric Muscle Stimulation on Injuries? (
  • Let's be honest, we've all seen commercial electrical muscle stimulation (EMS) devices before, but despite what those teleshopping commercials claim, they're really not that effective. (
  • Instead of the usual muscle stimulation patterns, BionicGym allegedly "mimics shivering, nature's way of burning calories without doing anything. (
  • Implicit pathophysiological mechanisms include microvascular, metabolic, electrical and bioenergetic changes, relating in a complex way and resulting in muscle atrophy and/or loss of muscle strength [2]. (
  • The brain stimulation techniques now being researched are, by contrast, generally quite mild. (
  • The stimulation] didn't hurt - more like a mild tingle or a static electric shock right on the top of my head. (
  • It looks just like a regular mouse but the catch is that it offers mild electric shocks. (
  • Aetna considers continued electrical stimulation not medically necessary once the wound demonstrates a 100 % epithelialized wound bed. (
  • The gadget comprises two small boxes with electrodes that are placed next to the skull and send a very weak, low-frequency electrical signal across the brain. (
  • The electrical stimulation is supposed to help strengthen a weak or dysfunctional LES ( 1 ). (
  • Scientists from Imperial College London (ICL) in the United Kingdom used electricity to stimulate the brain into synchronizing its waves of electrical activity. (
  • This paper for the first time discusses a computational study of using magneto-electric (ME) nanoparticles to artificially stimulate the neural activity deep in the brain. (
  • This is the non-provisional filing of application Serial No. 60/271,948, filed on Mar. 1, 2001, entitled "Electrical Method to Control Autonomic Nerve Stimulation of Gastrointestinal Tract. (
  • The 800 dpi mouse offers 20 levels of stimulation and three different modes of operation. (
  • Three different protocols of electrical stimulation, with 3 different electrical currents (AC, DC and pulsatile DC), were then compared for neural stem cell differentiation. (
  • Magnetic stimulation was performed with a figure-of-eight coil held over the right motor cortex at the optimum scalp position, in order to elicit motor responses in the contralateral FDI using two different orientations over the motor strip. (
  • The key finding is that you can, surprisingly, by scalp stimulation, influence the brain. (
  • The next step is to see if the brain stimulation works in patients with brain injury, in combination with brain imaging, where patients have lesions which impair long-range communication in their brains," Dr. Violante says. (
  • Investigators also say that the next step will investigate long-term effects of electric stimulation on the brain and find specific targets in the brain that may be more effective depending on the pain condition and patients' status. (
  • Fourteen epilepsy patients undergoing monitoring of seizures via intracranial depth electrodes viewed a series of neutral object images, half of which were immediately followed by brief, low-amplitude electrical stimulation to the amygdala. (
  • Amygdala stimulation elicited no subjective emotional response but led to reliably improved memory compared with control images when patients were given a recognition-memory test the next day. (
  • Physical therapists endure vigorous coursework and training for seven years and use electrical stimulation on a daily basis to help patients with injuries and ailments. (
  • The project is supposed to enable paraplegic patients with residual control over the leg musculature to walk a few steps or to stand up from their wheelchair by means of electrical stimulation. (
  • A remote transmitter allowed these patients to trigger electric stimulation to relieve their symptoms on an as-needed basis. (
  • In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the. (
  • a waveform generator configured to generate and deliver the stimulation pulse in a manner such that an amount of charge delivered to tissue during the stimulation pulse is equal to the stored charge setting value. (
  • Electric acoustic stimulation (EAS) is the use of a hearing aid and a cochlear implant together in the same ear. (
  • 70 dB HL) above 1 kHz can be beyond the range of amplification possible via acoustic stimulation. (
  • The concept of combining simultaneous electric-acoustic stimulation (EAS) for the purposes of better hearing was first described by C. von Ilberg and J. Kiefer, from the Universitätsklinik Frankfurt, Germany, in 1999. (
  • Bipolar stimulation ( Ac ) at 1.25 Hz, 0.4 V intensity. (
  • 2018) The Addition of Transcutaneous Electrical Nerve Stimulation with Roller Massage Alone or in Combination Did Not Increase Pain Tolerance or Range of Motion. (
  • Electrical stimulation of the brain and spinal cord may help treat the symptoms of rare movement disorders called neurodegenerative ataxias, according to a study published in the August 22, 2018, online issue of Neurology ® , the medical journal of the American Academy of Neurology. (
  • Nowak, L.G. and Bullier, J. (1998) Axons, but not cell bodies, are activated by electrical stimulation in cortical grey matter. (
  • Aetna considers interferential stimulation (e.g. (
  • Acupuncture combined with electric stimulation achieves the much better efficacy on dysphagia after acute stroke and promotes the early removal of nasal feeding tube. (
  • There have been several anecdotal accounts that cranial electrical stimulation (CES) enhances attention and the ability to learn new tasks in a normal population, but only one published investigation confirms that CES improves attention using the Alpha Stim CES (Madden and Kirsch, 1987). (