Use of electric potential or currents to elicit biological responses.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
Electronic hearing devices typically used for patients with normal outer and middle ear function, but defective inner ear function. In the COCHLEA, the hair cells (HAIR CELLS, VESTIBULAR) may be absent or damaged but there are residual nerve fibers. The device electrically stimulates the COCHLEAR NERVE to create sound sensation.
Order of mammals whose members are adapted for flight. It includes bats, flying foxes, and fruit bats.
The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing.
Artificial device such as an externally-worn camera attached to a stimulator on the RETINA, OPTIC NERVE, or VISUAL CORTEX, intended to restore or amplify vision.
Use of sound to elicit a response in the nervous system.
NEURAL PATHWAYS and connections within the CENTRAL NERVOUS SYSTEM, beginning at the hair cells of the ORGAN OF CORTI, continuing along the eighth cranial nerve, and terminating at the AUDITORY CORTEX.
In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672)
Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.
The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY.
A general term for the complete loss of the ability to hear from both ears.
The posterior pair of the quadrigeminal bodies which contain centers for auditory function.
A dimension of auditory sensation varying with cycles per second of the sound stimulus.
The audibility limit of discriminating sound intensity and pitch.
The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
The science pertaining to the interrelationship of psychologic phenomena and the individual's response to the physical properties of sound.
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Elements of limited time intervals, contributing to particular results or situations.
Fields representing the joint interplay of electric and magnetic forces.
The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
An order of neotropical electric fish found chiefly in the waters of South America. They continually emit weak electric discharges, which they use in object location and communication. A most popular species of research interest is the electric eel, ELECTROPHORUS electricus.
Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.
The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.
Act of eliciting a response from a person or organism through physical contact.
A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.
An arrangement of wires distributing electricity.
The ability of a substrate to allow the passage of ELECTRONS.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A technique in which electric pulses of intensity in kilovolts per centimeter and of microsecond-to-millisecond duration cause a temporary loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
Devices that control the supply of electric current for running electrical equipment.
A genus of the Torpedinidae family consisting of several species. Members of this family have powerful electric organs and are commonly called electric rays.
The resistance to the flow of either alternating or direct electrical current.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Burns produced by contact with electric current or from a sudden discharge of electricity.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
The rate dynamics in chemical or physical systems.
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.
The use of specifically placed small electrodes to deliver electrical impulses across the SKIN to relieve PAIN. It is used less frequently to produce ANESTHESIA.
A genus of fish, in the family GYMNOTIFORMES, capable of producing an electric shock that immobilizes fish and other prey. The species Electrophorus electricus is also known as the electric eel, though it is not a true eel.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Established cell cultures that have the potential to propagate indefinitely.
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
Communication between animals involving the giving off by one individual of some chemical or physical signal, that, on being received by another, influences its behavior.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
Electrodes with an extremely small tip, used in a voltage clamp or other apparatus to stimulate or record bioelectric potentials of single cells intracellularly or extracellularly. (Dorland, 28th ed)
The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The property of nonisotropic media, such as crystals, whereby a single incident beam of light traverses the medium as two beams, each plane-polarized, the planes being at right angles to each other. (Cline et al., Dictionary of Visual Science, 4th ed)
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
Units that convert some other form of energy into electrical energy.
Contractile tissue that produces movement in animals.
The function of opposing or restraining the excitation of neurons or their target excitable cells.
The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Induction of a stress reaction in experimental subjects by means of an electrical shock; applies to either convulsive or non-convulsive states.
Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Lens-shaped structure on the inner aspect of the INTERNAL CAPSULE. The SUBTHALAMIC NUCLEUS and pathways traversing this region are concerned with the integration of somatic motor function.
Characteristics of ELECTRICITY and magnetism such as charged particles and the properties and behavior of charged particles, and other phenomena related to or associated with electromagnetism.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
The time from the onset of a stimulus until a response is observed.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Neurons which activate MUSCLE CELLS.
Stimulation of the brain, which is self-administered. The stimulation may result in negative or positive reinforcement.
Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors.
The process in which specialized SENSORY RECEPTOR CELLS transduce peripheral stimuli (physical or chemical) into NERVE IMPULSES which are then transmitted to the various sensory centers in the CENTRAL NERVOUS SYSTEM.
The common name for all members of the Rajidae family. Skates and rays are members of the same order (Rajiformes). Skates have weak electric organs.
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Neural tracts connecting one part of the nervous system with another.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
The physical characteristics and processes of biological systems.
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
Computer-based representation of physical systems and phenomena such as chemical processes.

Inhibitory innervation of cat sphincter of Oddi. (1/19053)

1 Electrical stimulation with trains of 0.1-0.2 ms pulses of the cat isolated sphincter of Oddi inhibited the spontaneous contractile activity and lowered base-line tension considerably. A contraction usually followed the period of stimulation. 2 These inhibitory effects were prevented by tetrodotoxin 0.1-0.5 mug/ml but were not reduced by hexamethonilm, morphine, or blockade of alpha- or beta-adrenoreceptors of cholinoceptors with phenoxy-benzamine propranolol or atropine, respectively. 3 Adenosine-5'-triphosphate (ATP) and adenosine-5'-diphosphate (ADP) inhibited the spontaneous sphincter activity and caused relaxation thus mimicking the effects of the C-terminal octapeptide of cholecystokinin (C8-CCK), isoprenaline and prostaglandin E1 and E2. 4 ATP alone (greater than 100 mug/ml) or ATP (greater than 10 mug/ml) plus dipyridamole (1 mug/ml), relaxed the sphincter to the same degrees as did the field stimulation. 5 In sphincter maximally contracted by acetylcholine, the effect of stimulation was more marked than that recorded in uncontracted preparations. 6 The present findings suggest that the sphincter of Oddi receives inhibitory nerves that are neither cholinergic nor adrenergic.  (+info)

Further evidence that prostaglandins inhibit the release of noradrenaline from adrenergic nerve terminals by restriction of availability of calcium. (2/19053)

1 Guinea-pig vasa deferentia were continuously superfused after labelling the transmitter stores with [3H](-)-noradrenaline. Release of [3H]-(-)-noradrenaline was induced by transmural nerve stimulation. 2 Prostglandin E2 (14 nM) drastically reduced the release of [3H]-(-)-noradrenaline, while tetraethylammonium (2 mM), rubidium (6 mM), phenoxybenzamine (3 muM) each in the presence or absence of Uptake 1 or 2 blockade, and prolonged pulse duration (from 0.5 to 2.0 ms) all significantly increased the release of [3H]-(-)-noradrenaline per nerve impulse. 3 The inhibitory effect of prostaglandin E2 on evoked release of [3H]-(-)-noradrenaline was significantly reduced by tetraethylammonium, rubidium and prolonged pulse duration, whilst it was actually enhanced by phenoxybenzamine. This indicates that increased release of noradrenaline per nerve impulse does not per se counteract the inhibitory effect of prostaglandin E2. 4 It is concluded that tetraethylammonium, rubidium and prolonged pulse duration counteracted the inhibitory effect of prostaglandin E2 on T3H]-(-)-noradrenaline release by promoting calcium influx during the nerve action potential. The results are consistent with, and add more weight to the view that prostaglandins inhibit the release of noradrenaline by restriction of calcium availability.  (+info)

Automatic activity in depolarized guinea pig ventricular myocardium. Characteristics and mechanisms. (3/19053)

Membrane potential was changed uniformly in segments, 0.7-1.0 mm long, of guinea pig papillary muscles excised from the right ventricle by using extracellular polarizing current pulses applied across two electrically insulated cf preparations superfused with Tyrode's solution at maximum diastolic membrane potentials ranging from-35.2+/-7.5 (threshold) to +4.0+/-9.2 mV. The average maximum dV/dt of RAD ranged from 17.1 to 18.0 V/sec within a membrane potential range of -40 to +20 mV. Raising extracellular Ca2+ concentration [Ca2+]0 from 1.8 to 6.8 mM, or application of isoproterenol (10(-6)g/ml) enhanced the rate of RAD, but lowering [Ca2+]0 to 0.4 mM or exposure to MnCl2 (6 mM) abolished RAD. RAD were enhanced by lowering extracellular K+ concentration [K+]0 from 5.4 to 1.5 mM. RAD were suppressed in 40% of fibers by raising [K+]0 to 15.4 mM, and in all fibers by raising [K+]0 to 40.4 mM. This suppression was due to increased [K+]0 and not to K-induced depolarization because it persisted when membrane potential was held by means of a conditioning hyperpolarizing puled gradually after maximum repolarization. These observations suggest that the development of RAD in depolarized myocardium is associated with a time-dependent decrease in outward current (probably K current) and with increase in the background inward current, presumably flowing through the slow cha-nel carrying Ca or Na ions, or both.  (+info)

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (4/19053)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

The effect of cardiac contraction on collateral resistance in the canine heart. (5/19053)

We determined whether the coronary collateral vessels develop an increased resistance to blood flow during systole as does the cognate vascular bed. Collateral resistance was estimated by measuring retrograde flow rate from a distal branch of the left anterior descending coronary artery while the main left coronary artery was perfused at a constant pressure. Retrograde flow rate was measured before and during vagal arrest. We found that in 10 dogs the prolonged diastole experienced when the heart was stopped caused no significant change in the retrograde flow rate, which indicated that systole has little effect on the collateral resistance. However, when left ventricular end-diastolic pressure was altered by changing afterload or contractility, a direct relationship between end-diastolic pressure and collateral resistance was noted.  (+info)

Effect of electrotonic potentials on pacemaker activity of canine Purkinje fibers in relation to parasystole. (6/19053)

Isolated false tendons excised form dog hearts were mounted in a three-chamber tissue bath. Isotonic sucrose solution was perfused in the central chamber to provide a region of depressed conductivity between the fiber segments in chambers 1 and 3, which were perfused with Tyrode's solution. The electrotonic influence of spontaneous or driven responses evoked in chamber 3 during the first half of the spontaneous cycle of a chamber 1 peacemaker delayed the next spontaneous discharge. This effect changed to acceleration when the chamber 3 segment fired during the second half of the spontaneous cycle. We found that subthreshold depolarizing current pulses 50-300 msec applied across the sucrose gap caused similar degrees of delay or acceleration. Furthermore, hyperpolarizing currents caused the reverse pattern. The results indicate that the discharge pattern of a parasystolic focus may be altered by the electrotonic influence of activity in the surrounding tissue. The significance of these findings is considered in relation to the mechanism of production of parasystolic rhythms.  (+info)

Evaluation of the force-frequency relationship as a descriptor of the inotropic state of canine left ventricular myocardium. (7/19053)

The short-term force-frequency characteristics of canine left ventricular myocardium were examined in both isolated and intact preparations by briefly pertubing the frequency of contraction with early extrasystoles. The maximum rate of rise of isometric tension (Fmas) of the isolated trabeculae carneae was potentiated by the introduction of extrasystoles. The ratio of Fmas of potentiated to control beats (force-frequency ratio) was not altered significantly by a change in muscle length. However, exposure of the trabeculae to isoproterenol (10(-7)M) significantly changed the force-frequency ratio obtained in response to a constant frequency perturbation. Similar experiments were performed on chronically instrumented conscious dogs. Left ventricular minor axis diameter was measured with implanted pulse-transit ultrasonic dimension transducers, and intracavitary pressure was measured with a high fidelity micromanometer. Atrial pacing was performed so that the end-diastolic diameters of the beats preceding and following the extrasystole could be made identical. Large increases in the maximum rate of rise of pressure (Pmas) were seen in the contraction after the extrasystole. The ratio of Pmax of the potentiated beat to that of the control beat was not changed by a 9% increase in the end-diastolic diameter, produced by saline infusion. Conversely, isoproterenol significantly altered this relationship in the same manner as in the isolated muscle. Thus, either in vitro or in situ, left ventricular myocardium exhibits large functional changes in response to brief perturbations in rate. The isoproterenol and length data indicate that the force-frequency ratio reflects frequency-dependent changes in the inotropic state, independent of changes in length.  (+info)

Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection. (8/19053)

Excitatory synaptic transmission between pyramidal cells and fast-spiking (FS) interneurons of layer V of the motor cortex was investigated in acute slices by using paired recordings at 30 degrees C combined with morphological analysis. The presynaptic and postsynaptic properties at these identified central synapses were compared between 3- and 5-week-old rats. At these two postnatal developmental stages, unitary EPSCs were mediated by the activation of AMPA receptors with fast kinetics at a holding potential of -72 mV. The amplitude distribution analysis of the EPSCs indicates that, at both stages, pyramidal-FS connections consisted of multiple functional release sites. The apparent quantal size obtained by decreasing the external calcium ([Ca2+]e) varied from 11 to 29 pA near resting membrane potential. In young rats, pairs of presynaptic action potentials elicited unitary synaptic responses that displayed paired-pulse depression at all tested frequencies. In older animals, inputs from different pyramidal cells onto the same FS interneuron had different paired-pulse response characteristics and, at most of these connections, a switch from depression to facilitation occurred when decreasing the rate of presynaptic stimulation. The balance between facilitation and depression endows pyramidal-FS connections from 5-week-old animals with wide integrative capabilities and confers unique functional properties to each synapse.  (+info)

TY - JOUR. T1 - Twitch potentiation after voluntary contraction and neuromuscular electrical stimulation at various frequencies in human quadriceps femoris. AU - Miyamoto, Naokazu. AU - Fukutani, Atsuki. AU - Yanai, Toshimasa. AU - Kawakami, Yasuo. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Introduction: In this study we aimed to compare the extent of twitch potentiation (TP) after voluntary contraction and percutaneous electrical stimulation of muscles (neuromuscular electrical stimulation: NMES) with various stimulation frequencies at equivalent target levels. Methods: Isometric knee extensions of 10 s were performed at a 40% maximal voluntary contraction level by voluntary or NMES conditioning contractions at 20, 40, and 80 H Z of the quadriceps femoris muscle. Twitch responses were elicited by stimulating the femoral nerve transcutaneously at supramaximal intensity. Results: NMES at 80 HZ induced significantly less TP (128.7 ± 17.1%) than voluntary contraction (156.2 ± 23.1%), whereas no ...
The spatial extent of transcranial magnetic stimulation (TMS) is of paramount interest for all studies employing this method. It is generally assumed that the induced electric field is the crucial parameter to determine which cortical regions are excited. While it is difficult to directly measure the electric field, one usually relies on computational models to estimate the electric field distribution. Direct electrical stimulation (DES) is a local brain stimulation method generally considered the gold standard to map structure-function relationships in the brain. Its application is typically limited to patients undergoing brain surgery. In this study we compare the computationally predicted stimulation area in TMS with the DES area in six patients with tumors near precentral regions. We combine a motor evoked potential (MEP) mapping experiment for both TMS and DES with realistic individual finite element method (FEM) simulations of the electric field distribution during TMS and DES. On average, ...
Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo. med./bio. ...
Birba A, Hesse E, Sedeño L, Mikulan EP, García MDC, Ávalos J, Adolfi F, Legaz A, Bekinschtein TA, Zimerman M, Parra M, García AM, Ibáñez A. Enhanced Working Memory Binding by Direct Electrical Stimulation of the Parietal Cortex. Front Aging Neurosci. 2017 Jun 8;9:178. doi: 10.3389/fnagi.2017.00178 La memoria de trabajo de integración (WMB) es un marcador preclínico de la enfermedad de Alzheimer (EA) que depende de regiones posteriores del cerebro. La estimulación de la corteza parietal posterior (PPC) podría ser un target terapéutico en la EA. En este estudio, encontramos que la estimulación eléctrica y directa intracraneal de regiones específicas de la PPC durante la WMB induce una mejora selectiva en el desempeño.
Although initial studies suggested that the MEP in the rat arises from activation of the spinal pyramidal pathway, subsequent studies have raised doubts concerning the pyramidal origin of the MEP and have proposed that the spread of stimulation current in some of these studies resulted in activation of the extrapyramidal system. [18-24] Ryder and colleagues [24] showed that monopolar stimulation of the sensorimotor cortex activates the extrapyramidal and pyramidal tracts, and bipolar stimulation restricted to the motor cortex using low stimulus current activates only the pyramidal tract. They concluded that early and late latency spinal-evoked responses were considered to be induced by activation of extrapyramidal and pyramidal tracts, respectively. Although we used bipolar stimulation of the motor cortex in the present study, stimulus current was higher than that reported by Ryder and colleagues. [24] Both extrapyramidal and pyramidal tracts must be activated in the present study. However, it ...
Autor: Borchers, S et al.; Genre: Zeitschriftenartikel; Im Druck veröffentlicht: 2012-01; Titel: Direct electrical stimulation of human cortex: the gold standard for mapping brain functions?
A system for providing medical electrical stimulation, the system features a pulse generator, the pulse generator generating electrical stimulation pulses of a first amplitude and a second amplitude, first and second elongated leads coupled to the pulse generator, a zener diode which directs electrical stimulation pulses of a first amplitude to the first lead and directs electrical stimulation pulses of a second amplitude to the first lead and the second lead, the means for directing electrical stimulation pulses coupled to the pulse generator. In the preferred embodiment the diode is electrically coupled to one of the leads such that electrical stimulation of a first amplitude is not passed through the diode while electrical stimulation of a second amplitude is passed through the diode. Overall the adaptor permits a single channel of stimulation to be split and provided to two areas of the heart merely be adjusting the amplitude of the stimulation pulses.
Cortical stimulation mapping (CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function. Cortical stimulation mapping is used for a number of clinical and therapeutic applications, and remains the preferred method for the pre-surgical mapping of the motor cortex and language areas to prevent unnecessary functional damage. There are also some clinical applications for cortical stimulation mapping, such as the treatment of epilepsy. The history of cortical stimulation mapping dates back to the late 19th century. Neurologists David Ferrier and Victor Horsley were some of the first to utilize this technique. Ferrier and Horsley employed CSM to further grasp the structure and function of the ...
TY - JOUR. T1 - Spatial heterogeneity of transmembrane potential responses of single guinea-pig cardiac cells during electric field stimulation. AU - Sharma, Vinod. AU - Tung, Leslie. PY - 2002/7/15. Y1 - 2002/7/15. N2 - Changes in transmembrane voltage (Vm) of cardiac cells during electric field stimulation have a complex spatial- and time-dependent behaviour that differs significantly from electrical stimulation of space-clamped membranes by current pulses. A multisite optical mapping system was used to obtain 17 or 25 μm resolution maps of Vm along the long axis of guinea-pig ventricular cells (n = 57) stained with voltage-sensitive dye (di-8-ANEPPS) and stimulated longitudinally with uniform electric field (2, 5 or 10 ms, 3-62 V cm-1) pulses (n = 201). The initial polarizations of Vm responses (Vmr) varied linearly along the cell length and reversed symmetrically upon field reversal. The remainder of the Vm responses had parallel time courses among the recording sites, revealing a common ...
The present preliminary report describes the electrophysiological response of the cochlea during long-term stimulation. The data indicate that electrical stimulation at a rate of 1000 pulses per second does not appear to adversely affect the implanted cochlea ...
Direct electrical stimulation of the brain has emerged as a powerful treatment for multiple neurological diseases, and as a potential technique to enhance human cognition. Despite its application in a range of brain disorders, it remains unclear how stimulation of discrete brain areas affects memory performance and the underlying electrophysiological activities. Here, we investigated the effect of direct electrical stimulation in four brain regions known to support declarative memory: hippocampus (HP), parahippocampal region (PH) neocortex, prefrontal cortex (PF), and lateral temporal cortex (TC). Intracranial EEG recordings with stimulation were collected from 22 patients during performance of verbal memory tasks. We found that high γ (62-118 Hz) activity induced by word presentation was modulated by electrical stimulation. This modulatory effect was greatest for trials with poor memory encoding. The high γ modulation correlated with the behavioral effect of stimulation in a given brain region: it
NEW FINDINGS. What is the central question of this study? How does peripheral nerve stimulation (PNS) compare with neuromuscular electrical stimulation (NMES) used clinically to reduce muscle atrophy? What is the main finding and its importance? NMES resulted in progressive increases in M-wave duration and delay of muscle relaxation throughout a single stimulation protocol, findings not observed with PNS. This suggests PNS recruits from a wider pool of muscle fibres/motor units, providing a more favourable alternative to NMES for rehabilitation intervention.. ABSTRACT. Neuromuscular electrical stimulation (NMES) is increasingly viewed as a central tenet to minimise muscle loss during periods of disuse/illness - typically applied directly over a muscle belly. Peripheral nerve stimulation (PNS) is afforded less attention, despite providing a more global contractile stimulus to muscles. We investigated NMES versus PNS in relation to performance fatigability and peripheral contributions to voluntary ...
It is the function of a pacemaker to provide electrical stimulation pulses to the appropriate chamber(s) of the heart (atria or ventricles) in the event that the heart is unable to beat of its own (i.e. in the event that either the sinoatrial node fails to generate its own natural stimulation pulses at an appropriate sinus rate, or in the event such natural stimulation pulses do not effectively propagate to the appropriate cardiac tissue). Most modern pacemakers accomplish this function by operating in a demand mode where stimulation pulses from the pacemaker are provided to the heart only when the heart is not beating of its own, as sensed by monitoring the appropriate chamber of the heart for the occurrence of a P-wave or R-wave. If a P-wave or a R-wave is not sensed within a prescribed period of time (which period of time is usually referred to as the escape interval), then a stimulation pulse is generated at the end of this prescribed period of time and delivered to the appropriate heart ...
TY - JOUR. T1 - Corticospinal potentials after electrical and magnetic stimulation in man.. AU - Berardelli, A.. AU - Inghilleri, M.. AU - Cruccu, G.. AU - Manfredi, M.. PY - 1991. Y1 - 1991. N2 - The present report deals with our study of the descending volley evoked by both electrical and magnetic transcranial stimulation in man. We discuss the differences of these two techniques specifically as regards the latency and amplitude of evoked potentials. In both cases, electrodes were placed either in the epidural space or directly on the spinal cord. Following electrical stimulation, the descending volley consisted of an early wave which appeared at low stimulation intensity and increased in amplitude and decreased in latency when the strength of the stimulus was increased. At high stimulation intensities the early wave was followed by later waves which travel at the same speed as the initial wave. By delivering paired cortical stimuli, the early wave evoked by the test stimuli is present at ...
TY - JOUR. T1 - Inhibition of mitochondrial Ca2+ uptake affects phasic release from motor terminals differently depending on external [Ca2+]. AU - Talbot, Janet D.. AU - David, Gavriel. AU - Barrett, Ellen. PY - 2003/7/1. Y1 - 2003/7/1. N2 - We investigated how inhibition of mitochondrial Ca2+ uptake affects stimulation-induced increases in cytosolic [Ca2+] and phasic and asynchronous transmitter release in lizard motor terminals in 2 and 0.5 mM bath [Ca2+], Lowering bath [Ca2+] reduced the rate of rise, but not the final amplitude, of the increase in mitochondrial [Ca2+] during 50-Hz stimulation. The amplitude of the stimulation-induced increase in cytosolic [Ca2+] was reduced in low-bath [Ca2+] and increased when mitochondrial Ca2+ uptake was inhibited by depolarizing mitochondria. In 2 mM Ca2+, end-plate potentials (epps) depressed by 53% after 10 s of 50-Hz stimulation, and this depression increased to 80% after mitochondrial depolarization. In contrast, in 0.5 mM Ca2+ the same stimulation ...
Electrical stimulation of the central nervous system albeit an unnatural way, has been found to be an effective way of causing neuronal excitation. Retinal prosthesis is an example of such a neuroprosthesis that strives to provide vision to people suffering from Retinitis Pigmentosa and Age-related Macular Degeneration. In these diseases, the photoreceptors in the retina undergo a progressive degeneration leaving the remaining retinal neurons relatively intact. It is by electrically stimulating these retinal neurons that a retinal prosthesis aims to elicit visual percepts.; In addition to providing effective stimulation, such a device has to do so in a manner that is safe for both the device and surrounding biological environment. Numerous studies have been performed to assess the safety limits of electrical stimulation of neurons. However, majority of these studies have been performed in structures other than the retina. The few safety studies performed in the retina have looked at the effect ...
Local electrical stimulations of the ventral prelimbic cortex ameliorates depressive-like behavioral traits in a genetic rat model for major depression Conference Paper ...
Abstract: : Purpose: Nitric oxide is produced by many retinal neurons, however its ability to modulate synaptic activity in the inner retina is poorly understood. I examined how nitric oxide modulates the excitatory and inhibitory synaptic inputs to ganglion cells evoked by light and by focal electrical stimulation. Methods: I recorded postsynaptic currents from ganglion cells using whole-cell patch clamp techniques in retinal slices prepared under infrared illumination. Responses were elicited by a green LED (1 sec duration) and by brief focal electrical stimulation (zap; 1 msec; .1 - 1.5 µA) of the outer-plexiform layer. Strychnine (10 µM) was used to isolate the GABAergic inputs. Results: Nitric oxide has been shown to affect photoreceptor calcium currents, so I compared responses elicited by illumination with those elicited by the zap, which directly depolarizes bipolar cells to activate inputs to the inner plexiform layer. Application of the nitric oxide donor, NONOate (100 µM) rapidly ...
We tested six stimulation paradigms that consisted of either uniform trains of single pulses or patterned stimulation trains applied at variable low frequencies and either low- or high-intensity current. Low-intensity, prolonged stimulation at 1-5 Hz did not cause any changes but at 10 Hz reliably elicited homosynaptic depression, an effect that dissipated within 3 hr in every case (Figs. 1,2 A, 3 A). High-intensity, prolonged stimulation at 1 Hz still had no impact, but at 5 Hz caused a depression encompassing both pathways and recovering within 1-3 hr (Fig. 3 B). High-intensity current at stimulation of 10 Hz led to a complete and apparently permanent loss of the homosynaptic response, an effect that seemed pathological and of uncertain relevance to normal synaptic operations. Overall, the impact of uniform trains of low-frequency pulses was more pronounced the smaller interpulse intervals and the higher the current intensity. However, in no case did the depression last much longer than 3 ...
Thanks to the IGIA Electro Pulse Stimulation Massager you can get effective pain relief without medicine!This travel-size battery-powered massager is convenient not only to aid in body pain conditions but also in slimming down. This product is great for relieving tiredness, relaxing muscles, improving blood circulation
Methods and apparatus for testing of the efficacy of therapeutic stimulation of pelvic nerves or musculature to alleviate one of incontinence or sexual dysfunction are disclosed. A therapy delivery device is operable in a therapy delivery mode and a test mode and an evoked response detector is employed in the test mode to detect the evoked response to applied test stimuli. The test stimuli parameters of the test stimulation regimen are adjusted prior to delivery of each test stimulation regimen, and the evoked responses to the applied test stimulation regimens are compared to ascertain an optimal test stimulation regimen. The therapy stimulation regimen parameters are selected as a function of the test electrical stimulation parameters causing the optimal evoked response.
During initial acquisition sessions the frequency was held constant (156 Hz) and the intensity was adjusted by the experimenter to determine the lowest intensity that maintained high rates of responding (more than 40 responses/min). Once responding was established, frequency-response curves were generated. These 2-h sessions consisted of six 10-min components, which were further broken down into ten 1-min trials. Each 60-s trial consisted of a 5-s timeout, then a 5-s period during which five noncontingent stimulations were delivered, and finally a 50-s period in which lever presses resulted in stimulation and were recorded. During these sessions the intensity remained the same (unique to each animal) and 10 frequencies (156-45 Hz, 0.06 log increments) corresponding to each trial were presented in descending order. A 1-h timeout period between the third and fourth components permitted drug injections during test sessions. During test sessions when fentanyl was administered, the timeout period was ...
A computer stimulated the prefrontal cortex exactly when braking was needed. This was done using electrodes implanted directly on the brain surface.. When the test was repeated with stimulation of a brain region outside the prefrontal cortex, there was no effect on behavior, showing the effect to be specific to the prefrontal braking system.. This was a double-blind study, meaning that participants and scientists did not know when or where the charges were being administered.. The method of electrical stimulation was novel in that it apparently enhanced prefrontal function, whereas other human brain stimulation studies mostly disrupt normal brain activity. This is the first published human study to enhance prefrontal lobe function using direct electrical stimulation, the researchers report.. The study involved four volunteers with epilepsy who agreed to participate while being monitored for seizures at the Mischer Neuroscience Institute at Memorial Hermann-Texas Medical Center (TMC). Stimulation ...
In general, the disclosure describes implantable pulse generators (IPGs) adapted to deliver stimulation to refractory myocardial tissue. An IPG nominally delivers one to six monophasic stimulation pulses. Because monophasic stimulation tends to accumulate polarization, a programmable blanking period of between about 20 milliseconds (ms) and about 300 ms is implemented (subsequent to delivery of the last pulse in a RPS pulse train) to allow recovery from polarization. The stimulation pulse width is about 0.03 ms to about 1.6 ms and voltage amplitude of 0.5 volts to 8 volts at about 50 Hz. The amplitude of electrical current of the stimulation pulses is less than or equal to approximately 50 milliamps. The pulses are delivered to multiple sites within a cardiac chamber and device performance and/or diagnostic information can be stored within a memory structure and reviewed to confirm delivery of a desired therapy regimen.
Vital Tones Muscle Stimulation Upper Body is an exclusive brainwave sound therapy for stimulating nerves and muscles of the upper body. Vital Tones stimulates nerves and muscles naturally through the specific parts of the motor cortex and the cerebellum. Vital Tones Muscle Stimulation can be used for the following: - Relaxation of muscle spasms; - Prevention or retardation of disuse. atrophy; - Increasing local blood circulation; - Muscle re-education; - Maintaining or increasing range of. motion. Vital Tones Muscle Stimulation Upper Body Pro consists of 7 different sessions. Session 1 and 2 is 12 minutes and the others 10 minutes long. Vital Tones Muscle Stimulation Upper Body trial version consists of only one session.
Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.
When surgery and medication dont help people with epilepsy, electrical stimulation of the brain has been a treatment of last resort. Unfortunately, typical approaches, such as vagal nerve stimulation or responsive nerve stimulation, rarely stop seizures altogether. But a new Mayo Clinic study in JAMA Neurology shows that seizures were suppressed in patients treated with…
Systems of and methods for stimulation of neurological tissue that may generate stimulation trains with temporal patterns of stimulation is shown and disclosed herein. The temporal patterns of stimulation may include intervals between electrical pulses (the inter-pulse intervals) that change or vary over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention may provide a lower average frequency.
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A study of activity recorded with intracellular micropipettes was undertaken in the caudal abdominal ganglion of the crayfish in order to gain information about central fiber to fiber synaptic mechanisms. This synaptic system has well developed integrative properties. Excitatory post-synaptic potentials can be graded, and synaptic potentials from different inputs can sum to initiate spike discharge. In most impaled units, the spike discharge fails to destroy the synaptic potential, thereby allowing sustained depolarization and multiple spike discharge following single pulse stimulation to an afferent input. Some units had characteristics which suggest a graded threshold for spike generation along the post-synaptic fiber membrane. Other impaled units responded to afferent stimulation with spike discharges of two distinct amplitudes. The smaller or abortive spikes in such units may represent non-invading activity in branches of the post-synaptic axon. On a few occasions one afferent input was ...
For each band of gaba synapses, this function makes a file with the // stimulation train and shifts the activation time (by temporal_offset) // written by Yiota Poirazi, July 2001, [email protected] double iary[1000] objref vary[1000], s_file, stimtmp, rpid stimtmp = new Vector() strdef shiftsyn_filename, syscmd, estr proc gaba_shift() { local synapses, temporal_offset, hertz, gmax_default, PID, lo, hi synapses = $1 // number of synapses in the band tstop = $2 // stimulation end time dt = $3 hertz = $4 // stimulation train frequency synch = $5 // synchronous or a synchronous stimulation of synapses perio = $6 // periodic or not periodic stimulation PID = $7 PID = abs(PID) // only positive random seeds used for spike train generation temporal_offset = $8 // shift stimulation time by temporal_offset // Make the desired activation pattern file and // Set GABA pointers to activation pattern sprint(shiftsyn_filename,gaba_shiftsyn-%d-%.2f-%.2f-%.2f-%.2f-%.2f-%d-%.2f,\ ...
TY - JOUR. T1 - Low-frequency stimulation induces stable transitions in stereotypical activity in cortical networks. AU - Vajda, I.. AU - van Pelt, J.. AU - Wolters, P.. AU - Chiappalone, M. AU - Martinoia, S. AU - van Someren, E.J.W.. AU - van Ooyen, A.. PY - 2008. Y1 - 2008. N2 - Reverberating spontaneous synchronized brain activity is believed to play an important role in neural information processing. Whether and how external stimuli can influence this spontaneous activity is poorly understood. Because periodic synchronized network activity is also prominent in in vitro neuronal cultures, we used cortical cultures grown on multielectrode arrays to examine how spontaneous activity is affected by external stimuli. Spontaneous network activity before and after low-frequency electrical stimulation was quantified in several ways. Our results show that the initially stable pattern of stereotypical spontaneous activity was transformed into another activity pattern that remained stable for at least ...
The Electric Eric provides both vibration and electrical stimulation at the same time and it DOES NOT require a nerve stimulator kit so no cables or added devices needed. Features two vibration motors: one in the tip and in the shaft with 8 different vibration programs and 5 different intensity levels along with 5 electrical stimulation programs with 10 different levels of intensity.
We induced atrioventricular dissociation and initiated ventricular pacing in intact dogs and isolated cat hearts. Left ventricular pressure, its time derivative (dP/t), and action potentials were recorded. When a test pulse was introduced at varying intervals after a period of steady pacing, an optimum contractile response was obtained at an average interval of 720 msec. A similar optimum interval was obtained after pacing at various frequencies and after paired pulse stimulation but was shortened to 560 msec after infusion of epinephrine. The magnitude of the optimum contractile response increased with an increase in the frequency of prior pacing which was accompanied by an increase in the time the cell membrane was depolarized. The optimum contractile response following paired pulse stimulation was greater than that following regular pacing, with the same number of stimuli per minute and the same time of membrane depolarization. The results are explicable in terms of intracellular calcium ion ...
Electrical Stimulation: How Does it Work and Why You May Not Need It. Electrical stimulation is a wonderful tool that physical therapists can use on a regular basis. There are different types of electrical stimulation units. These different types of units create different types of waveforms are and are used for very different reasons. Some waves help to reduce pain by stimulating certain parts of nerves that can send painful signals to the brain. Others can cause muscle contractions which can help to strength muscles. How does it work? Often patients are curious as to how electrical stimulation works. The specific wavelengths, frequencies, ramp up times and other technical aspects can be a bit overwhelming. These things are important to know if you want to get the most out of your experience with electrical stimulation. However, the basic concept of electrical stimulation is pretty simple.. Electricity is the language of our nervous system. All of our nerves, including the brain and spinal cord, ...
A method of verifying cardiac capture. A cardiac signal evoked in response to a cardiac stimulation pulse is sensed via an electrode. The sensed signal is lowpass filtered to remove noise and to pass frequencies characteristic of the evoked cardiac signal. The filtered signal is processed to render a waveform signal representing the second derivative of said filtered signal and the second derivative signal is further analyzed to detect a minimum and a maximum amplitude excursion during a selected window of time beginning at a selected time delay following delivery of the cardiac stimulation pulse. The amplitude difference between the minimum and the maximum is measured and compared to a first reference value. The amplitude of the second derivative is measured during a second selected window of time beginning at a selected time delay following delivery of said cardiac stimulation pulse, and compared to a second reference value. A capture detect signal is generated if the amplitude difference exceeds the
A method of verifying cardiac capture. A cardiac signal evoked in response to a cardiac stimulation pulse is sensed via an electrode. The sensed signal is lowpass filtered to remove noise and to pass frequencies characteristic of the evoked cardiac signal. The filtered signal is processed to render a waveform signal representing the second derivative of said filtered signal and the second derivative signal is further analyzed to detect a minimum and a maximum amplitude excursion during a selected window of time beginning at a selected time delay following delivery of the cardiac stimulation pulse. The amplitude difference between the minimum and the maximum is measured and compared to a first reference value. The amplitude of the second derivative is measured during a second selected window of time beginning at a selected time delay following delivery of said cardiac stimulation pulse, and compared to a second reference value. A capture detect signal is generated if the amplitude difference exceeds the
TY - JOUR. T1 - GABAergic inhibition shapes frequency adaptation of cortical activity in a frequency-dependent manner. AU - Heistek, Tim S.. AU - Lodder, Johannes C.. AU - Brussaard, Arjen B.. AU - Bosman, Laurens W. J.. AU - Mansvelder, Huibert D.. PY - 2010/3/19. Y1 - 2010/3/19. KW - Short-term plasticity. KW - Neuronal network. KW - GABA. KW - Voltage-sensitive dye imaging. KW - Benzodiazepine. U2 - 10.1016/j.brainres.2010.01.047. DO - 10.1016/j.brainres.2010.01.047. M3 - Article. C2 - 20114035. VL - 1321. SP - 31. EP - 39. JO - Brain Research. JF - Brain Research. SN - 0006-8993. ER - ...
a, b, Speed profiles of mice after the stimulation of Vglut2+ChR2 CnF (a) and Vglut2+ChR2 PPN (b) neurons. Top panels show the location of optical stimulation in the CnF (a) and the PPN (b). Middle panels show colour plots of individual trials after the stimulation of Vglut2+ChR2 CnF (a) and Vglut2+ChR2 PPN (b) neurons (Fig. 1). The x axis represents time and the y axis represents trials at different stimulation frequencies. Data are aligned to the onset of stimulation (stim.). The colour gradient illustrates speed, with dark blue representing no movement and colours towards yellow representing the increase in speed (up to 120 cm s−1) of the mouse in the linear corridor. Bottom panels show speed profiles obtained as an average of the movements at each stimulation frequency. c, Latencies to onset of locomotion from the stimulation of Vglut2+ChR2 PPN (red) and Vglut2+ChR2 CnF (blue) neurons as a function of the stimulation frequency. Error bars indicate the 25th and 75th percentiles of the ...
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Another important challenge remains in our limited understanding of the specific mechanisms by which stimulation causes its effects, or in other words, what neurophysiological changes occur between the stimulation and the behavioral changes. For example, does applying direct electrical current with short pulses at a low frequency induce a low-frequency oscillation, particularly at the stimulation frequency? Studies sometimes make such implicit assumptions, but the field is lacking a fundamental insight to accept or modify such assumptions. Encouraging advances have been made on this end for TMS (Thut and Miniussi, 2009, Thut and Pascual-Leone, 2009 and Vernet et al., 2013), transcranial alternating current stimulation (tACS; Fröhlich and McCormick, 2010 and Herrmann et al., 2013), and direct brain stimulation (Logothetis et al., 2010 and Tolias et al., 2005). For example, Vernet et al. (2013) used a combined TMS-EEG approach to evaluate the cortical effects of continuous theta-burst stimulation ...
Case Study: System on a Chip for Electric Stimulation: 10.4018/978-1-5225-0190-9.ch011: Integrated circuits have been predominantly designed and developed by large firms and manufacturers; nowadays, any electronic engineer should be able to
Fingerprint Dive into the research topics of Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report. Together they form a unique fingerprint. ...
New Delhi, August 1 The Indian Army is preparing to maintain its current strength of troops, tanks and other weaponry in all key areas in eastern Ladakh in the harsh winter months as a resolution to
Mystim Sizzling Simon E-Stim | Sizzling Simon provides an unprecedented vibration and electrical stimulation at once! No cables or devices Sizzling Simon vibrates, tingles and
The present study has three main results: (1) Processing of different shape stimuli results in activity patterns that in single trials are surprisingly well distinguishable in the local field potential of area V4. (2) Selective attention substantially enhanced the stimulus-dependent differences of these neural activity patterns for the attended stimulus. (3) Behavioral failures went along with a reduction of classification performance. The components of the signal most discriminative for different shapes were contained in the γ-band above 40 Hz and their stimulus-specific characteristics stayed similar during different stimulation periods in a trial. The attention-dependent enhancement of stimulus discriminability cannot be explained by a simple increase of the SNR, but turns out to be most strongly related to a stimulus-specific differential scaling of the frequency components. This scaling results in an enhanced separation between the characteristic frequency patterns in the γ-band for ...
We performed two classes of control experiments to validate the results. First, nontransgenic littermates (n = 9) were injected with Cre-dependent ChR2-EYFP AAV and subjected to the same stimulation paradigm as the experimental animals. Separately, TH::IRES-Cre transgenic mice (n = 9) were injected with Cre-dependent ChR2-EYFP AAV but received no optical stimulation during conditioning to further control for spontaneous preference shifts. Neither control group showed a significant CPP (Fig. 3E right, P , 0.5 by Students t test). Furthermore, we did not find any significant changes in anxiety-related behaviors (Fig. 3G) or in locomotor activity (Fig. 3H) during preference tests and in open field tests (fig. S6).. Next, we tested whether the CPP effect observed was due to an appetitive effect from 50-Hz stimulation or to an aversive effect from 1-Hz stimulation. We compared the effect of each firing modality with no stimulation in two independent cohorts. Consistent with the previous CPP ...
Intraoperative optical imaging (IOI) is a marker-free, contactless, and noninvasive imaging technique that is able to visualize metabolic changes of the brain surface following neuronal activation. Although it has been used in the past mainly for the identification of functional brain areas under general anesthesia, the authors investigated the potential of the method during awake surgery. Measurements were performed in 10 patients who underwent resection of lesions within or adjacent to cortical language or motor sites. IOI was applied in 3 different scenarios: identification of motor areas by using finger-tapping tasks, identification of language areas by using speech tasks (overt and silent speech), and a novel approach-the application of IOI as a feedback tool during direct electrical stimulation (DES) mapping of language. The functional maps, which were calculated from the IOI data (activity maps), were qualitatively compared with the functional MRI (fMRI) and the electrophysiological ...
Positive effects of tDCS in patients in MCS was showed in a recent study published in Neurology. But the effects went down after 1 or 2 hours. To increase the lasting of the effects, a new study will evaluate the effects of tDCS on the left prefrontal dorsolateral cortex for 5 consecutive days in chronic patients in MCS.. 2 sessions of 5 days of stimulation will be realized, one session will be real (anodal stimulation) and one placebo (sham stimulation). After each stimulation, behavioral improvement will be assessed with the Coma Recovery Scale Revised (CRS-R). A final assessment will be done one week after the end of the sessions to assess the long term effect of the tDCS.. Researchers expected to see an improvement of the CRS-r total score at the end of the anodal session and that this improvement persists for a week. ...
Electric Muscle Stimulation Therapy is a new approach in treating various pain issues utilizing electrical muscle stimulation to reach deeper layers of the muscles. It is often used by physical therapists and your local Wesley Chapel chiropractor for localized pain relief especially for muscle pains such as fibromyalgia and muscle strains. The mechanism of the muscle stimulation is it delivers small pulsating currents directly on the muscles, which in turn promotes muscle stimulation, blood circulation and muscle healing.. The main benefit of electrical muscle stimulation therapy is pain relief. The electrical currents allow the muscles to release tension and stress relieving muscle soreness, tightness and body aches. For joint pains, electric muscle stimulation therapy also may improve joint symptoms as relaxation of the smooth muscles around a painful joint can help foster healing from joint inflammation.. Using electric muscle stimulation therapy not only provides effective muscle pain ...
We studied the effects of intense sympathetic stimulation on the chronotropic responses of the heart to subsequent test stimulations of the cardiac autonomic nerves in dogs anesthetized with alpha-chloralose. Such intense sympathetic stimulations (which we refer to as release stimulations) are known to release neuropeptide Y as well as norepinephrine. The changes in cardiac cycle length evoked by vagal and sympathetic test stimulations were progressively more attenuated as we increased the frequency and duration of the antecedent sympathetic release stimulations. We found that 2.5 minutes after a maximal release stimulation (30 Hz for 5 minutes), the mean +/- SEM chronotropic responses to the vagal and sympathetic test stimulations were diminished to 36.5 +/- 1.6% and 54.7 +/- 1.3% respectively, of the prestimulation responses. The mean times for the chronotropic responses to the vagal and sympathetic test stimulations to recover to their control values were 52.0 +/- 1.3 and 63.2 +/- 2.9 ...
TLTE - Tension Lag Time on Electric Stimulation. Looking for abbreviations of TLTE? It is Tension Lag Time on Electric Stimulation. Tension Lag Time on Electric Stimulation listed as TLTE
To determine whether high current strength pacing at the site of origin of ventricular tachycardia (VT) could prevent induction of VT, we studied 11 VTs in 10 patients with chronic coronary artery disease. The left ventricular site of origin of all VT was determined by endocardial catheter mapping. Reproducible VT induction from the right ventricular apex or outflow tract was demonstrated with a pacing current strength equal to twice diastolic threshold (less than or equal to 2.0 mA) with single (two VTs), double (eight VTs), or triple (one VT) extrastimuli following 8 beats of a drive cycle length of 400 to 600 msec. After determination of the baseline VT induction zone (range 10 to 80 msec), repeat induction was attempted while simultaneous pacing was performed during the 8 beat drive train from the left ventricular site of origin with the use of a high current strength (10 mA [two VTs] or 20 mA [nine VTs]) and from the baseline right ventricular site with a current strength equal to twice ...
To investigate whether electrical stimulation promoted axonal regeneration of retinal ganglion cells (RGCs) after optic nerve (ON) crush in adult rats. Transcorneal electrical stimulation (TES), which stimulates the retina with current from a corneal contact lens electrode, was used to stimulate the eye. TES was applied for 1 h immediately after ON crush. Axonal regeneration was determined by anterograde labeling of RGC axons. To examine whether the axonal regeneration was mediated by insulin-like growth factor 1 (IGF-1) receptors, an IGF-1 receptor antagonist, JB3, was injected intraperitoneally before each TES application. Immunostaining for IGF-1 was performed to examine the effects of TES. To test the survival-promoting effects of TES applied daily, the mean density of retrogradely labeled RGCs was determined on day 12 after ON crush. Compared with sham stimulation, the mean number of regenerating axons significantly increased at 250 microm distal from the lesion and increased IGF-1 ...
An automated adaptive muscle stimulation system and method are disclosed. The stimulation system includes at least one electrode assembly adapted to deliver a muscle stimulation signal to the tissue of a user, a sensor system adapted to detect a muscle response, and an electrical stimulation device operably coupled to the at least on electrode assembly and the sensor system, the electrical stimulation device including a control system operable to automatically diagnose at least one characteristic of a muscle from the detected muscle response and adjust at least one parameter of the muscle stimulation signal in response thereto to deliver an adjusted muscle stimulation signal. A dual mode muscle stimulation system adapted to accept first and second data sets and provide first and second levels of treatment data is also disclosed.
An implantable neural stimulation device and method treats peripheral vascular disease of a patient. The device includes a pulse generator that provides stimulation pulses and an implantable lead that applies the stimulation pulses to neural tissue. An activity sensor senses activity level of the patient and a processor, responsive to the activity sensor, controls the provision of the stimulation pulses by the pulse generator. The processor causes the pulse generator to provide stimulation therapy any time the patient is active or when the patient is at rest. The processor further provides long term activity monitoring and closed loop control of neural tissue stimulation levels to adapt the stimulation therapy to changes in the patients condition.
Electrical Muscle Stimulation is a way to provoke muscle contraction by means of electric stimulus. The impulses are generated by a device and delivered through electrodes on the skin in direct proximity to the muscles to be stimulated. The impulses mimic the central nervous system, initiating the contracting of the muscles. EMS is both electrotherapy and muscle training ...
TY - JOUR. T1 - Effect of graded electrical stimulation on blood flow to healthy muscle. AU - Currier, D. P.. AU - Petrilli, C. R.. AU - Threlkeld, A. J.. PY - 1986. Y1 - 1986. N2 - The purpose of this study was to determine whether 2,500-Hz sine-wave electrical stimulation modulated at 50 bursts per second producing graded muscular responses affects blood flow. Healthy volunteer subjects were assigned randomly to an Experimental group (n=14) that received bursts of electrical stimulation to the gastrocnemius muscle or to a Control group (n=14) that received no treatment. Using a Doppler device, pulsatility index (PI) values were determined for multivariate statistical analysis. Electrical stimulation graded to simulate isometric torques equivalent to 10% and then 30% of the subjects isometric maximum voluntary contraction resulted in respective mean increases in PI values of 20.5% and 19.6% over prestimulation PI values. We found no significant difference in PI values between the two levels of ...
Electrical Muscle Stimulation - Electric stimulation therapy involves low levels of electrical impulses delivered to injured tissues to reduce pain and promote faster healing. Patients
The Centers for Disease Control and Prevention (2015) declared that 80% of U.S. adults do not meet exercise recommendations by ACSM. Skeletal muscle contraction has been shown to increase mitochondrial content (energy production) and glucose uptake (decreased insulin resistance). Neuromuscular Electrical Stimulation (NMES) utilizes electrical impulses to induce muscle contractions and can be used as an alternate strategy to induce muscle contraction in sedentary adults. However, it is not clear if NMES induced muscle contraction may improve insulin sensitivity and metabolic health. PURPOSE: The purpose of this study was to investigate the effects of two weeks of NMES on insulin sensitivity, energy expenditure, and body composition in a sedentary population. METHODS: Five female participants (age 23±1 yrs, BMI 24.08±1.36 kg/m2, maximal aerobic capacity 35.4±2.80 ml/kg/min) performed six sessions (20-minutes, 3x/week) of quadriceps electrical stimulation over the course of two weeks. Maximal aerobic
0033] FIG. 2 illustrates a neural stimulator, and further illustrates various neural stimulation parameters that can be adjusted to adjust a neural stimulation therapy, according to various embodiments of the present subject matter. According to various embodiments, the neural stimulator 209 includes modules to set or adjust any one or any combination of two or more of the following pulse features delivered to the neural stimulation electrode(s) or transducer(s): the amplitude 210 of the stimulation pulse, the frequency 211 of the stimulation pulse, the burst frequency 212 of the pulse, the wave morphology 213 of the pulse, and the pulse width 214. Examples of neural stimulation electrodes include nerve cuffs, and intravascularly-fed electrodes to transvascularly stimulate a neural target. Examples of neural transducers include ultrasound, magnetic and light transducers used to stimulate a neural target. The illustrated burst frequency pulse feature 212 includes burst duration 215 and duty cycle ...
RC Walk-In Chiro utilizes Winnipeg Electrical Muscle Stimulation to send electrical impulses to your muscles promoting muscle contractions. Call today!
TY - GEN. T1 - EMS icons. T2 - 2017 ACM International Joint Conference on Pervasive and Ubiquitous Computing and ACM International Symposium on Wearable Computers, UbiComp/ISWC 2017. AU - Dingler, Tilman. AU - Goto, Takashi. AU - Tag, Benjamin. AU - Kunze, Kai Steven. PY - 2017/9/11. Y1 - 2017/9/11. N2 - Electrical Muscle Stimulation (EMS) has recently received an increased amount of attention from the HCI community. It has been used to remote control users for navigation and instrument playing, but also as a method to convey haptic feedback in VR, for example. As EMS devices become commercially available and application research continues, we explore EMS as a modality to convey information through actuation and as a means to induce and communicate emotions and moods. In this position paper, we present the results from two focus groups on using EMS for interpersonal communication as a way to send and receive emoticons through electrical stimulation. We argue that so-called EMS Icons have the ...
Electrical Muscle Stimulation - Here at Forzani Family Chiropractic, we are proud to offer e-stim to our patients. Stimulation can be a fantastic tool to assist you in feeling better.
electro muscle stimulation_Electrical muscle stimulation WikipediaElectrical muscle stimulation (EMS), also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is the elicitation of muscle EMS
Determination of Excitation Thresholds for Retina Ganglion Cells Using Biphasic and Monophasic Stimulation Pulses to be Designed for High Resolution Epiretinal Prosthesis ...
TY - GEN. T1 - Effect of muscular strengthening with electrical stimulation on sit-to-stand motion in young and elderly persons. AU - Galli, M.. AU - Crivellini, M.. PY - 1998. Y1 - 1998. N2 - The ability to get up from a chair is an important component in maintaining independence for elderly persons and for individuals with disabilities. The main aim of this work is to investigate the effect of muscular strengthening on sit-to-stand (STS) movement to get round the muscular weakness that often occur in elderly people. The sit-to-stand movement of 18 young persons and 10 elderly healthy subjects were acquired before and after an electrical stimulation (ES) strengthening cycle. Experimental data collected by using an optoelectronic system (ELITE), an EMG telemetric equipment and a force platform were analyzed by using a biomechanical planar model. The rising strategies and hip knee and ankle joint torques in the two different groups were calculated before and after ES cycle. The results showed ...
Start Over You searched for: Authors Beard, George M. (George Miller), 1839-1883 ✖Remove constraint Authors: Beard, George M. (George Miller), 1839-1883 Subjects Electric Stimulation Therapy ✖Remove constraint Subjects: Electric Stimulation Therapy Titles Medical and surgical cases treated by electricity ✖Remove constraint Titles: Medical and surgical cases treated by electricity Publication Year 1874 ✖Remove constraint Publication Year: 1874 Dates by Range 1850-1899 ✖Remove constraint Dates by Range: 1850-1899 ...
Cyclosporin A administration is associated with an increased incidence of hypertension. To evaluate the direct effects of the drug on the contractile responses of vascular tissue to adrenergic stimuli, rat caudal artery ring segments were studied before and after the addition of cyclosporin A or its ethanol vehicle in vitro. In a dose-related manner, cyclosporin A augmented the contractile response to transmural nerve stimulation, with a highly significant (p less than 0.001 relative to that produced by the vehicle) lowering of the stimulation rate, a 50% of maximum contractile response (ED50) that elicited. The difference between pretreatment and treatment maximal responses to transmural nerve stimulation was also significantly greater (p less than 0.01) in the cyclosporin A-treated preparations than in those receiving the vehicle. In similar experiments, the responses to exogenous norepinephrine were not significantly affected. The effect of cyclosporin A on transmural nerve stimulation was ...
a valid model for myotonic dystrophy, was assessed, using an in vivo force assessment device, used in conjunction with EMG recording. The aim of the study was to verify whether the muscle force assessment device we developed was capable to sensitively detect the typical characteristics of myotonic muscle. To date, two wild-type and four myotonic female mice have been assessed. After anesthetic induction by isoflurane, the mice were positioned in the apparatus. Hindlimb muscles were stimulated noninvasively by electrodes placed on the muscle of the leg being stimulated. After establishing optimal muscle length, muscle force was assessed after single pulse stimulation at supramaximal voltage followed by double, triple and quadruple pulses. Both legs from each animal were tested and included in the analyses. Muscle force characteristics (peak force, half relaxation time, and area under the force curve (AUC)) and EMG data were recorded and analyzed. Peak forces generated in the myotonic mice were ...
Various aspects of the present subject matter provide a filter module. In various embodiments, the filter module comprises an input, an output, a signal path from the input to the output, a filter and a switch. The filter has a transfer response to attenuate a frequency of a neural stimulation signal. The switch is adapted to place the filter in the signal path when the neural stimulation signal is applied and to remove the filter from the signal path when the neural stimulation signal is not applied. Other aspects are provided herein.
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The effects of dl-metanephrine (300 µg/kg i.v.) were determined on responses of the nictitating membrane to norepinephrine, to phenylephrine and to nerve stimulation. After the administration of metanephrine there was an increase in responses of the normal nictitating membrane to norepinephrine and to pnenylephrine in the lower part of the dose-response curve. The rest of the dose-response curve was practically superimposed on the corresponding controls. A similar pattern was observed for the denervated (2 days) nictitating membrane. Responses to pre- and to postganglionic stimulation obtained after the administration of metanephrine were increased for the range of low frequencies of stimulation. The rest of the frequency-response curve was superimposed on the control curve. The increase in responses in the lower part of the response curves was shown to be due to the additive effects of metanephrine and the injected sympathomimetic amine or the endogenously released norepinephrine. It is ...
Welcome to Odstock Medical the leading manufacturer of Clinical Functional Electrical Stimulation systems (FES) together with the associated treatments for patients who are effected by a dropped foot or upper limb disability.
EMS - ELECTRICAL MUSCLE STIMULATION FOR SPORT TRAINING. We have the lowest online prices in the WORLD! GLOBUS has been one of the leaders in Electrical Muscle Stimulation for Sport Training for over 30 years. With its high technological and scientific competence, it offers reliable products for evaluation, electrostimulation and electrotherapy.. Electrical Muscle Stimulation is a tool to complement training and recovery. Many have heard about EMS for rehabilitation but few have heard how valuable it can be to compliment training and to speed up recovery from rigorous training rides and races.. To activate additional savings on EMS units use coupon code GlobusCart during checkout.. Trust us you will get the best price online by using this code.. This offer cannot be combined with any additional discount(s).. ... offers 5,265 electric muscle stimulation weight loss machine products. About 71% of these are other beauty equipment, 12% are vacuum cavitation system, and 9% are multi-functional beauty equipment. A wide variety of electric muscle stimulation weight loss machine options are available to you, such as breast enhancers, weight loss, and cellulite reduction.
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The Report provides a detailed Global Electrical Stimulation Devices ESD Industry overview along with the analysis of industrys gross margin, cost structure, consumption value, and sale price, Processing Techniques, Network Management, Services Offered, Related Softwares Market, Social Media Marketing, Cost Structure, Supply Chain, Development Management Techniques, Retailers Analysis, Financial Support, business Strategies, Marketing Channels, Market Entry Strategies, Industry Development Challenges and Opportunities, Investment Plans, Economic Impact on Electrical Stimulation Devices ESD Market.. Inquiry about Report at: Global Electrical Stimulation Devices ESD Market Chapterwise Description :-. The First Chapter covers Electrical Stimulation Devices ESD basic introduction, marketplace overview, product scope, market opportunities, market risk, and market driving force. The Second Chapter deals ...
1. Release of [3H]noradrenaline during peri-arterial nerve stimulation and its inhibition by the presynaptic α-adrenoceptor mechanism were studied in the isolated perfused kidney from spontaneously hypertensive and Wistar-Kyoto rats.. 2. A frequency related vasoconstriction as well as [3H]noradrenaline release were observed over the stimulating range of 0.25-32 Hz in both the Wistar-Kyoto and spontaneously hypertensive rats. The spontaneously hypertensive rat kidneys exhibited both an increased vasoconstrictor response and a greater [3H]noradrenaline release when compared with the Wistar-Kyoto rat kidneys.. 3. Presynaptic inhibition of [3H]noradrenaline release was evaluated at 2 Hz by using the α-adrenoceptor agonist, tramazoline. Increasing concentrations of tramazoline from 2 × 10−9 mol/l to 2 × 10−7 mol/l caused a dose-dependent decrease in the stimulus-induced release of [3H]noradrenaline in spontaneously hypertensive rats but not in Wistar-Kyoto rats. Only 2 × 10−7 mol/l ...
Various programming techniques are described for medical devices that deliver electrical stimulation therapy that may include mapping between discrete electrical stimulation parameters and a graphical view of the electrical stimulation representing a stimulation zone generated by the parameters. In one example, a method includes receiving, via a programmer for an electrical stimulator, user input that graphically manipulates at least one of size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer, and defining a program to control delivery of electrical stimulation therapy based on the user input.
Percutaneous tibial nerve stimulation - Electrical impulses are applied to the nerves that control bladder function.. Choose Spire Cambridge Lea Hospital.
Currently, the study of nociception in humans relies mainly on thermal stimulation of heat-sensitive nociceptive afferents. To circumvent some limitations of thermal stimulation, it was proposed that intra-epidermal electrical stimulation (IES) could be used as an alternative method to activate nociceptors selectively. The selectivity of IES relies on the fact that it can generate a very focal electrical current and, thereby, activate nociceptive free nerve endings located in the epidermis without concomitantly activating non-nociceptive mechanoreceptors located more deeply in the dermis. However, an important limitation of IES is that it is selective for nociceptors only when very low current intensities are used. At these intensities, the stimulus generates a very weak percept, and the signal-to-noise ratio of the elicited evoked potentials (EPs) is very low. To circumvent this limitation, it was proposed that the strength of the nociceptive afferent volley could be increased through temporal ...
Part I Theory and Applications; Introduction - Excitable Tissue. Predictive Models. Overview.; Theoretical Foundations - Basic Equations. Cable Equation Relationships. Spatial Relationships. Mechanisms of Interaction. Alternative Models for Membrane Electrodynamics. Research Topics for Chapter 2.; Excitation Relationships - Threshold of Excitation. Strength-Duration Relationships. Power Supply Demand. Nonlinear Interaction of Multiple Stimulus Waveforms. Repetitive Stimulus Effects. Research Topics for Chapter 3. ; Threshold Criteria in Practical Applications - General Principles. Threshold Relationships. Research Topics for Chapter 4.; Selective Activation and Inhibition - General Aspects. Fiber Diameter Relationships. Selective Activation or Inhibition. Research Topics for Chapter 5.; Model Application to C-Fibers and the Heart - General Objectives. Electrostimulation of Nerve Fibers and Cardiac Muscle. Electrostimulation Characteristics of Cardiac Tissue. SENN Model Adaptation for A-Fibers, ...
Adenylyl cyclases contain two conserved homologous cytoplasmic domains (C1 and C2) that form the catalytic core of the enzyme [21]. Forskolin appears to induce the assembly of these two domains by interacting with the catalytic cleft [21-23]. The affinity between C1 and C2 is also facilitated by Gαs binding. These data have been confirmed by the finding that Forskolin and Gαs stimulate synergistically the cyclase activity [22]. In the presence of Gαs the affinity of Forskolin for the dimer C1/C2 is high (Kd = 0.1 μM), which suggests a stronger affinity for the complete cyclase molecule [23]. The site of interaction of the cyclase (type I or II) for beta/gamma has been located in the C1 b region. This site is independent of the Gαs and Forskolin interaction domains[24]. These findings argue in favor of isolating the cyclase(s) and its associated proteins using Forskolin-agarose affinity chromatography although this procedure enriches indistinctly the different isoforms of the cyclase family. ...
Background: Most U.S. adults (80%) do not meet minimum exercise recommendations by ACSM (CDC, 2015). Using an in vitro primary cell culture model, we and others have shown that muscle contraction induced by electrical stimulation results in increased glucose transporter 4 (GLUT4) protein, glucose uptake and mitochondrial content. Neuromuscular electrical stimulation (NMES) is a novel alternate strategy to induce muscle contraction, using electrical impulses. However, effectiveness of NMES induced muscle contraction to improve insulin sensitivity and energy expenditure is not clear. The purpose of this study was to investigate the effects of four weeks of NMES on insulin sensitivity in a sedentary overweight/obese population. Methods: Sedentary overweight/obese participants (n=10; age: 36.8 ± 3.8 years; BMI= 32 ± 1.3 kg/m2) were randomized into either a control or NMES group. All participants received bilateral quadriceps stimulation (12 sessions; 30 minutes/session; 3 times/week) either using low
Electric muscle stimulation trains your muscles in a way that traditional workouts alone cant. EMS, also known as neuromuscular electric stimulation, muscle stim, or e-stim, is delivered through electronic pulses to your nerve fibers in order to create involuntary muscle contractions. Unlike TENS, EMS waveforms activate fast twitch and slow twitch muscle fibers allowing the muscles to be stimulated to the point of exhaustion (relaxation) thus healing them to become stronger. This is similar to weight training. Muscles support joints and ligaments creating better support.. ...
A Functional Electric Stimulation unit (FES) stimulates nerves and muscles to give the patient more natural movement and stability. It is often used for patients with stroke, multiple sclerosis, cerebral palsy and brain or spinal cord injuries. It re-educates muscles to reduce muscle loss, increase local blood circulation and maintain or improve a range of motion ...
0 UserClasses Electrode An current injection electrode inserted in the middle of the current section which can be switched between current and voltage clamp modes and can do simple voltage clamp families. usage: section e = new Electrode([xplacement, yplacement]) e.stim and can used to set parameters programatically. Electrode can be saved in a .session file and is best used anonymously so that it is dismissed and point processes deleted when the graphic is dismissed. ?1 IClamp Switches the Electrode to single pulse current injection. Uses IClamp point process. ? del Time (ms) of the onset of the current stimulus relative to t = 0. ? dur Duration (ms) of the current stimulus ? amp Amplitude (mV) of the current stimulus ?1 VClamp Switches the Electrode to two electrode voltage clamp. Uses VClamp point process that allows up to three level changes. The clamp is set to be ideal. ?2 dur0 dur1 dur2 Duration in milliseconds of each level change starting at t=0. Each level is concatenated. At t = ...
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We also were able to fit Hunter with a loaner cart. The therapy seems to be working. By mid-April Hunter he was able to stand and support himself for 20 seconds with balance support, which is continuing to progress. On 5/20 Vicki noted he was walking independently on the hydro-treadmill and we no longer needing to use his tail for balance support. Hunter is progressively improving his mobility with his right rear limb, and a video from Vicki is starting to show movement in the left rear. From a medical point of view, Hunter is also continuing to improve. Hunter is currently on a 12 week course of antibiotics and repeat radiographs are showing no further damage in the hip joint. Vicki is continuing to bring Hunter to therapy and perform the neuromuscular electrical stimulation at home, with the goal of getting his mobility back to 100%. Great job by Vicki and keep with it Hunter!. ...
With just-suprathreshold current pulses, FS cells often displayed a considerable delay before the first spike, whereas GIN cells did not (cf. Fig. 2, C and D, top panels). In addition, GIN cells often displayed an afterdepolarization (ADP) following low-frequency action potentials (Fig. 2C, inset; cf. Halabisky et al. 2006). At higher levels of stimulus current, spike frequency adaptation was evident in GIN cells (Fig. 2D, bottom), but not in FS cells (Fig. 2D, bottom). Finally, at higher stimulus currents, the peak of the first action potential in GIN cells was the most positive in the train and the trough of the first afterhyperpolarization (AHP) was the most negative (Fig. 2C, bottom). By contrast, the action potential heights and AHP magnitudes of FS cells changed little under similar conditions (Fig. 2D, bottom). The firing of GIN cells also differed from that of RS cells, whose second action potential peak was substantially more negative than the first and whose first AHP was the most ...
The behavioral effects of direct electrical stimulation of the cingulum bundle, a white matter tract in the brain, were confirmed in two other epilepsy patients undergoing diagnostic monitoring. The findings are scheduled for publication in the Journal of Clinical Investigation. Videos of the effects of cingulum bundle stimulation are available, with the patients identity obscured.. Emory neurosurgeons see the technique as a potentially transformative way to calm some patients during awake brain surgery, even for people who are not especially anxious. For optimal protection of critical brain functions during surgery, patients may need to be awake and not sedated, so that doctors can talk with them, assess their language skills, and detect impairments that may arise from resection.. Even well-prepared patients may panic during awake surgery, which can be dangerous, says lead author Kelly Bijanki, PhD, assistant professor of neurosurgery. This particular patient was especially prone to it ...
Model Number: BK111A-#0954 Brand Name: OEM Key Specifications/Special Features: Body building abdomen muscle stimulation slimming beltBody building slender shaper muscle stimulation slimming belt Electric acupuncture LCD display Lithium batter...
Welcome to Odstock Medical the leading manufacturer of Clinical Functional Electrical Stimulation systems (FES) together with the associated treatments for patients who are effected by a dropped foot or upper limb disability.
... is a pacemaker-like device with electrical connections to the surface of the stomach. The device ... Gastric electrical stimulation, also known as implantable gastric stimulation, is the use of specific devices to provide ... Levinthal, DJ; Bielefeldt, K (January 2017). "Systematic review and meta-analysis: Gastric electrical stimulation for ... Chiu, JD; Soffer, E (January 2015). "Gastric electrical stimulation for obesity". Current Gastroenterology Reports. 17 (1): 424 ...
... above 1 kHz can be beyond the range of amplification possible via acoustic stimulation. Electric stimulation (CI), on the other ... Electric acoustic stimulation (EAS) is the use of a hearing aid and a cochlear implant technology together in the same ear. EAS ... Electric stimulation of the auditory system via cochlear implant is a commonly used technique for individuals with a severe to ... Gstoettner W., Helbig S., Maier N., Kiefer J., Radeloff A., Adunka O. (2006). Ipsilateral Electric Acoustic Stimulation of the ...
... (EMS), also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is the ... Electroacupuncture Functional electrical stimulation Microcurrent electrical neuromuscular stimulator Transcutaneous electrical ... This is distinct from transcutaneous electrical nerve stimulation (TENS), in which an electric current is used for pain therapy ... Electrical muscle stimulation can be used as a training, therapeutic, or cosmetic tool. In medicine, EMS is used for ...
... (EBS), also referred to as focal brain stimulation (FBS), is a form of electrotherapy used as a ... Deep transcranial magnetic stimulation (Deep TMS) Responsive nerve stimulation (RNS) Strong electric currents may cause a ... Low Field Magnetic Stimulation (LFMS) Functional electrical stimulation (FES) Magnetic seizure therapy (MST) Vagus nerve ... Electrical brain stimulation was first used in the first half of the 19th century by pioneering researchers such as Luigi ...
... (TES) is a therapy developed for use in patients with a variety of eye diseases. The ... Perin C, Viganò B, Piscitelli D, Matteo BM, Meroni R, Cerri CG (2020). "Non-invasive current stimulation in vision recovery: a ...
"Functional electrical stimulation device and system, and use thereof", issued 2014-09-29 [3], "Electrical stimulation system ... An electrical stimulation can artificially elicit this action potential by changing the electric potential across a nerve cell ... Functional electrical stimulation (FES) is a technique that uses low-energy electrical pulses to artificially generate body ... "Simulation of the three-dimensional electrical field in the course of functional electrical stimulation". Artificial Organs. 26 ...
... is a form of anti-reflux surgery, intended to assist in correcting a problem with the ... "Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (LES) Is Successful in Treating GERD - Final Results of ... EndoStim's proprietary technology uses functional electrical stimulation (a type of neuromodulation) to restore esophageal ... electrical stimulation therapy significantly and consistently increased LES pressure. An open-label trial conducted in Chile ...
... (TENS or TNS) is the use of electric current produced by a device to stimulate the ...
... is a neuromuscular stimulation treatment for idiopathic scoliosis. It is also known as ... It is a non-invasive scoliosis treatment that utilizes electrical muscle stimulation, which is also known as neurostimulation ... Eckerson, LF; Axelgaard, J (1984). "Lateral electrical surface stimulation as an alternative to bracing in the treatment of ... Axelgaard, J; Brown, JC (1983). "Lateral electrical surface stimulation for the treatment of progressive idiopathic scoliosis ...
... is a non-invasive brain stimulation technique and a form of transcranial electrical stimulation (tES). Terney et al from ... Transcranial random noise stimulation (tRNS) Transcranial pulsed current stimulation (tPCS) tRNS stimulation differs from tDCS ... 2019 Effects of Short-Term Random Noise Electrical Stimulation on Dissociated Pyramidal Neurons from the Cerebral Cortex. ... Paulus, Walter (1 October 2011). "Transcranial electrical stimulation (tES - tDCS; tRNS, tACS) methods". Neuropsychol Rehabil. ...
In transcranial magnetic stimulation (TMS), an electric coil is held above the region of interest on the scalp that uses ... Sham stimulation emits a brief current but then remains off for the remainder of the stimulation time. With sham stimulation, ... There are three different types of stimulation: anodal, cathodal, and sham. The anodal stimulation is positive (V+) stimulation ... Cranial electrotherapy stimulation Transcranial alternating current stimulation Transcranial random noise stimulation ...
Urinary incontinence Fecal incontinence Transcutaneous electrical nerve stimulation (TENS) Electrical muscle stimulation ... Sacral nerve stimulation, also termed sacral neuromodulation, is a type of medical electrical stimulation therapy. It typically ... TENS (transcutaneous electrical nerve stimulation) was patented and first used in 1974 for pain relief. TENS is non-invasive; ... By penetrating the skin, sacral nerve stimulation aims to give a direct and localized electric current to specific nerves in ...
Cortical stimulation mapping Cranial electrotherapy stimulation Electrical brain stimulation Electroconvulsive therapy Low ... Aetna (2013-10-11). "Clinical Policy Bulletin: Transcranial Magnetic Stimulation and Cranial Electrical Stimulation". Number ... current stimulation Transcranial direct-current stimulation Transcranial random noise stimulation Vagus nerve stimulation NICE ... TMS stimulates cortical tissue without the pain sensations produced in transcranial electrical stimulation. TMS can be used ...
"Gastric Electrical Stimulation". The Regents of The University of California. Retrieved 12 March 2016. "Chapter 1, Part 2, ... Electrical implants are being used to relieve pain from rheumatoid arthritis. The electric implant is embedded in the neck of ... "Arthritis sufferers offered hope after electrical implants leave". The Independent. 23 December 2014. Retrieved 1 February 2019 ... patients with rheumatoid arthritics, the implant sends electrical signals to electrodes in the vagus nerve. The application of ...
"Electric Acoustic Stimulation". Retrieved 2022-05-13. "Vibrant Soundbridge Middle Ear Implant". ... In 2005, MED-EL released their first electric acoustic stimulation system (EAS). This new type of implant combines both ... "Who is a Candidate for an Electric-Acoustic Stimulation (EAS) Cochlear Implant?". AudiologyOnline. Retrieved 2022-05-13. " ... The Bonebridge bone conduction implant was the first implant on the market to offer direct drive stimulation of the bone ...
It provides electrical stimulation to muscles which is equal to jogging three miles per week. A well-known example is that ... Neuromuscular Electric Stimulation (NMES): A form of treatment originally developed to combat muscle atrophy in space that has ... Neuromuscular Electrical Stimulation as a method to prevent muscle atrophy. After long space flight missions, astronauts may ... Lake, David A. (1992-05-01). "Neuromuscular Electrical Stimulation". Sports Medicine. 13 (5): 320-336. doi:10.2165/00007256- ...
Electrical stimulation of partial limb regeneration in mammals. Becker RO, Spadaro JA. Bull N Y Acad Med. 1972 May;48(4):627-41 ... Mollon B, da Silva V, Busse JW, Einhorn TA, Bhandari M (November 2008). "Electrical stimulation for long-bone fracture-healing ... Kooistra BW, Jain A,1 and Hanson BP (April-June 2009). "Electrical stimulation: Nonunions". Indian J Orthop. 43 (2): 149-55. ... The Body Electric: Electromagnetism and the Foundation of Life is a 1985 book by Becker and Gary Selden in which Becker, an ...
Alongside the manual stimulation, electric stimulation (2 to 5 Hz) was also given to four of the ten needles. The treatment ... Smith PS; Dinse HR; Kalisch T; Johnson M; Walker-Batson D (December 2009). "Effects of repetitive electrical stimulation to ... Sensory Stimulation uses rapid stimulation of nerves in a section of skin to drive neuronal changes in the participant. The ... explored the impact of frequency of stimulation on sensory stimulation techniques to induce plastic changes. The study ...
Patterson, Michael; Kesner, Raymond (1981). Electrical Stimulation Research Techniques. Academic Press. ISBN 0-12-547440-7. ... This coupling results in an electric body force in the bulk liquid, outside the electric double layer, that can generate ... These instabilities are caused by a coupling of electric fields and ionic conductivity gradients that results in an electric ... In such case, the moving structure acts as an electric motor. Practical fields of interest of EHD are the common air ioniser, ...
"Deep Brain Stimulation for Movement Disorders". University of Pittsburgh. Young RF & Brechner T (1986). "Electrical stimulation ... Orgasmic ecstasy was reported with the electrical stimulation of the brain with depth electrodes in the left hippocampus at 3mA ... Video: Deep brain stimulation to treat Parkinson's disease Video: Deep brain stimulation therapy for Parkinson's disease The ... open-loop VS closed loop stimulation, meaning a constant stimulation or an A.I. monitoring delivery system and (3) calibration ...
They demonstrated that electrical stimulation of peripheral nerves suppresses the perception of pain. A period of semi- ... Occipital nerve stimulation (ONS), also called peripheral nerve stimulation (PNS) of the occipital nerves, is used to treat ... painful direct muscle stimulation, lead movement with loss of stimulation, lead fracture, battery failure, eventual need for ... Electrical impulses are sent through the lead and its position is adjusted until the patient reports a "pins-and-needles" ...
For this reason, electrical brain stimulation provides a tool for identifying the reward circuitry within the central nervous ... Brain Stimulation: Can Magnetic or Electrical Pulses Help You?: Targeting Misbehaving Brain Circuitry with Therapies like ECT, ... Electrical brain stimulation and intracranial drug injections produce robust reward sensation due to a relatively direct ... Olds J, Milner P (1954). "Positive reinforcement produced by electrical stimulation of septal area and other regions of rat ...
It is used as a treatment for gastroparesis.[citation needed] Soffer, Edy E (2012). "Gastric Electrical Stimulation for ...
Siegert, M.; Tan, A. (2019). "Electric stimulation of ammonotrophic methanogenesis". Frontiers in Energy Research. 7: 17. doi: ... At the same time, they unload the liberated electrons onto the anode, producing electrical current. This electrical current can ... Another, still unexplored, reaction mechanism involves anaerobic ammonium oxidation on anodes of bio-electrical systems. Such ...
Mindes, Janet; Dubin, Mark J.; Altemus, Margaret (November 15, 2014). "Chapter 11 Cranial Electric Stimulation". In Knotkova, ... February 17, 2012 Electrical Stimulators Need High-Risk Rating, Says FDA Panel Staff, Sleep Review. June 11, 2014 FDA To ... Rigorous clinical trial evidence is lacking on the use of cranial electrotherapy stimulation (CES) in acute depression. Thus, ... Kavirajan HC, Lueck K, Chuang K (2014). "Alternating current cranial electrotherapy stimulation (CES) for depression". Cochrane ...
Since electrical stimulation itself sometimes seemed to quiet tremor during the procedure, Benabid reasoned this might be a ... As described in a 2010 interview with Benabid in the medical journal Lancet, electrical stimulation was used during surgery to ... International Functional Electrical Stimulation Society (IFESS). January 19, 2012. Retrieved March 1, 2014. Benabid, A.L. ( ... As technology advanced to allow such stimulation to be continuously applied for a long time, DBS became widely adopted in the ...
Rolston JD, Desai SA, Laxpati NG, Gross RE (October 2011). "Electrical stimulation for epilepsy: experimental approaches". ... Therefore, the main goal of neural decoding is to characterize how the electrical activity of neurons elicit activity and ... a neuron's electric potential fluctuates around its resting potential due to a constant influx and efflux of sodium and ... they may find what appears to be random electrical activity. These neurons are actually firing in response to the lower level ...
Cochrane Wounds Group) (January 2020). "Electrical stimulation for treating pressure ulcers". The Cochrane Database of ... electrical stimulation). Reliable scientific evidence to support the use of many of these interventions, though, is lacking. ... electrical stimulation). Reliable scientific evidence to support the use of many of these interventions, though, is lacking. ... of randomized controlled trials concluded that more research is needed to determine whether or not electrical stimulation is an ...
Electrical stimulation can promote nerve regeneration. The positive effect of electrical stimulation on nerve regeneration is ... Other methods of preventing peripheral nerve injury include electrical nerve stimulation and ultrasonography. Electrical ... Electrical stimulation also results in the influx of calcium ions, which further triggers multiple regeneration pathways. The ... Lu MC, Ho CY, Hsu SF, Lee HC, Lin JH, Yao CH, Chen YS (11 December 2007). "Effects of electrical stimulation at different ...
using evoked potentials and electrical stimulation. Experiments involving ablation of the second somatosensory cortex in ... Areas S2 in the left and right hemispheres are densely interconnected, and stimulation on one side of the body will activate ... and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation". J ...
Fink has joint appointments in the Departments of Electrical & Computer Engineering, Biomedical Engineering, Systems & ... neural stimulation, MEMS fabrication, data fusion and analysis, and multi-dimensional optimization. Wolfgang Fink publications ...
The AV node's normal intrinsic firing rate without stimulation (such as that from the SA node) is 40-60 times/minute. This ... Atrioventricular conduction disease (AV block) describes impairment of the electrical continuity between the atria and ... and conducts the normal electrical impulse from the atria to the ventricles. The AV node is quite compact (~1 x 3 x 5 mm). The ... it is part of the electrical conduction system of the heart. The AV node lies at the lower back section of the interatrial ...
... stimulation is the application of non-invasive neurostimulation techniques on the cerebellum to modify its electrical activity ... Deep brain stimulation Transcranial alternating current stimulation (tACS) Transcranial random noise stimulation (tRNS) ... Techniques such as transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS) can be used. The ... van Dun, Kim; Manto, Mario (27 December 2017). "Non-invasive Cerebellar Stimulation: Moving Towards Clinical Applications for ...
The most infamous of these episodes was Cyber Soldier Porygon (でんのうせんしポリゴン, Dennō Senshi Porygon, commonly Electric Soldier ... "コンテンツビジネスラボ「リーチ力・支出喚起力ランキング」 〜「コンテンツファン消費行動調査2018」より〜" [Content Business Lab "Reach Power / Expenditure Stimulation Ranking" 〜 ... "コンテンツビジネスラボ「リーチ力・支出喚起力ランキング」~「コンテンツファン消費行動調査2019」より~" [Content Business Lab "Reach Power / Expenditure Stimulation Ranking" ~ ... "コンテンツビジネスラボ
A variety of external stimuli like heat, light, solvent, an electric field, magnetic field, etc. can act upon a metal-organic ... featuring one-dimensional diamond-shaped pores that can expand or contract upon stimulation, such as adsorption of guest ...
Calcium Channel Blockers: Help slow the heart rate by blocking the number of electrical impulses that pass through the AV node ... vagal stimulation) LAMB:p. 35 Lidocaine Amiodarone Mexiltene/ Magnesium Beta-blocker Never let monkeys eat bananas: Neutrophils ... A procedure in which electric currents are used to reset the heart's rhythm back to regular pattern. Pirates:p. 3 Pulmonary: PE ... into the lower heart chambers (ventricles). Digoxin: Helps slow the heart rate by blocking the number of electrical impulses ...
The complexity of the reflex can be estimated by examining the time delay, or latency, between the electrical stimulation of ... Electromyographic and kinematic responses to electrical stimulation. Journal of Neurophysiology, 77(6), 3311-3325. Zehr, E. P ... Electromyographic and kinematic responses to electrical stimulation. Journal of Neurophysiology, 77(6), 3311-3325. Zehr, E. P ... Electromyographic and kinematic responses to electrical stimulation. Journal of Neurophysiology, 77(6), 3311-3325. Zehr, E. P ...
These action potentials cause the smooth muscle cells to contract or relax, depending on the particular stimulation the cells ... The basal or basic electrical rhythm (BER) or electrical control activity (ECA) is the spontaneous depolarization and ... This electrical rhythm is spread through gap junctions in the smooth muscle of the GI tract. These pacemaker cells, also called ... The basal electrical rhythm allows the smooth muscle cell to depolarize and contract rhythmically when exposed to hormonal ...
The Penfield mood organ is a fictional device in Philip K. Dick's 1968 science fiction novel Do Androids Dream of Electric ... The device is described in the novel as using "Penfield artificial brain stimulation". A "Penfield wave transmitter" is also ... Beckett, Chris (2015-05-21). "The Penfield Mood Organ in Do Androids Dream of Electric Sheep?". Retrieved 2022-10-13. ... "Penfield Wave Transmitter by Philip K. Dick from Do Androids Dream of Electric Sheep?". Retrieved 2022-10- ...
... discovered electrical stimulation of the brain Jack Pickup (1919-1996) - general practitioner and surgeon, also known as the " ... invented the electric cooking range and the electric car heater Anthony R. Barringer (1925-2009) - holds 70 patents for mineral ... electric wheelchairs, microsurgical staple gun, the ZEEP nuclear reactor, and the Canadarm James L Kraft (1874-1953) - ... co-inventor of the first electric light bulb Charles Fenerty (c. 1821-1892) - inventor of the wood pulp process for making ...
Exploiting Stochastic Effects of Electrical Stimulation". Annals of Otology, Rhinology & Laryngology. 112 (9_suppl): 14-19. doi ...
"Classification of methods in transcranial electrical stimulation (tES) and evolving strategy from historical approaches to ... She claimed to be able to treat drug addiction using electric shocks, something she called "neuro-electric therapy" (NET). The ... "Howson backs electric heroin cure". The Scotsman. 24 December 2006. Shapiro, Harry (1988). Waiting for the Man: The Story of ... As of 2012, evidence reviewed within NHS Scotland found no substantial evidence that neuro-electric therapy was helpful in ...
Mayer, D. J.; Wolfle, T. L.; Akil, H.; Carder, B.; Liebeskind, J. C. (1971-12-24). "Analgesia from electrical stimulation in ... Another member of the lab observed that electrical stimulation reduced, rather than enhanced pain experience, which inspired ... they discovered that the narcotic antagonist naloxone partially reverses analgesia produced by focal electrical stimulation of ... "stimulation produced analgesia" (SPA). Working on rats, they found that stimulation at several mesencephalic and diencephalic ...
Section 1 of the body acupuncture with needles without electrical stimulation for chronic headache, chronic lumbar pain, ... 135 Abs.1 SGB V der Körperakupunktur mit Nadeln ohne elektrische Stimulation bei chronischen Kopfschmerzen, chronischen LWS- ...
The reflex decreases the transmission of vibrational energy to the cochlea, where it is converted into electrical impulses to ... The main hypothesized function of the acoustic reflex is the protection of the organ of Corti against excessive stimulation ( ... Moreover, the full tension of the stapedius muscle cannot be maintained in response to continued stimulation. Indeed, the ... no matter which ear was exposed to the loud sound stimulation. The prevalence of bilateral acoustic reflexes in persons 18-30 ...
Among these are a unique study to evaluate the value of activity-based rehab and FES, functional electrical stimulation, for ...
... a study showing that it is possible read a person's spatial memories by using a brain scanner to monitor the electrical ... Neuroscience and the Functional Imaging Laboratory published the results of a study using transcranial magnetic stimulation ...
... "might be brought about by direct stimulation of someone's brain, in the absence of any relevant desire or intention on the part ... the build-up of electrical signal called the readiness potential (after German Bereitschaftspotential, which was discovered by ...
Further, it has been shown that electrical stimulation of IL reduces conditioned fear and strengthens extinction memory[ ...
1979). "effects of physical conditioning and electric stimulation on metabolic processes in the soleus muscle and structure ... These findings reinforce the notion that it is the mechanical activity rather than the electrical activity imposed on the ... Miller, TF; Saenko, IV; Popov, DV; Vinogradova, OL; Kozlovskaya, IB (July 2004). "Effect of mechanical stimulation of the ... electrical activity, and tone. At the structural level, the loss of muscle volume in these models correlates with a significant ...
... activation is often induced experimentally by direct electrical stimulation of a presumed target structure. ...
The electrical properties of neurons are controlled by a wide variety of biochemical and metabolic processes, most notably the ... than animals whose levels of stimulation are restricted. The functions of the brain depend on the ability of neurons to ... When large numbers of neurons show synchronized activity, the electric fields that they generate can be large enough to detect ... As a side effect of the electrochemical processes used by neurons for signaling, brain tissue generates electric fields when it ...
... which the receiver uses to convert the detected radiation to an electric current. That electrical signal is passed through a ... Brook, P. J. (26 April 1969). "Stimulation of Ascospore Release in Venturia inaequalis by Far Red Light". Nature. 222 (5191): ... Smith, Willoughby (20 February 1873). "Effect of light on selenium during the passage of an electric current". Nature. 7 (173 ... and to detect the overheating of electrical components. Military and civilian applications include target acquisition, ...
Electromechanical Stimulation is the application of electrical currents or soundwaves to produce a healing and/or analgesic ( ... Gunn C.C.; 2007, The Gunn Approach to the Treatment of Chronic Pain - Intramuscular Stimulation for Myofascial Pain of ...
Transcutaneous electrical nerve stimulation (TENS) therapy is often used to treat various types of neuropathy. A 2010 review of ... Jin DM, Xu Y, Geng DF, Yan TB (July 2010). "Effect of transcutaneous electrical nerve stimulation on symptomatic diabetic ... Gibson W, Wand BM, O'Connell NE (September 2017). "Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in ... which affects the ability of the axons to conduct electrical impulses. The third and least common pattern affects the cell ...
General Electric TP-110, p. 23, table. Contag CH, Bachmann MH (2002). "Advances in in vivo bioluminescence imaging of gene ... are opened to allow the entry of protons from a vacuole possessing an action potential produced from a mechanical stimulation. ...
Penfield had over 25 years of research using electrical stimulation to produce experiential hallucinations. His conclusions ... Penfield reported that stimulation of the temporal lobes could lead to vivid recall of memories. Oversimplified in popular ... These experiences would only last as long as the electrode stimulations were present on the cortex, and in some cases when ... Other stimulations had patients experiencing déjà vu, fear, loneliness, and strangeness. Certain areas of patients' temporal ...
Vagus nerve stimulation is another alternative treatment that has been proven to be effective in the treatment of depression, ... Electroconvulsive therapy is a treatment in which a generalized seizure is induced by means of electrical current. The ... Transcranial magnetic stimulation is also an alternative treatment for a major depressive episode. It is a non-invasive ... Some of the unique benefits of vagus nerve stimulation include improved neurocognitive function and a sustained clinical ...
... Med Sci Sports Exerc. 1995 Dec;27(12):1671-6. ...
Lower esophageal sphincter electrical stimulation improved symptoms, lowered esophageal acid exposure, and allowed most ... Cite this: GERD Symptoms Improved by Electrical Stimulation - Medscape - Oct 26, 2012. ... lower esophageal sphincter electrical stimulation (LES-EST) improved symptoms, lowered esophageal acid exposure, and reduced ... Stimulation sensation was not strong.. "Over 12 months, we were pretty much able to get people off PPI therapy and to ...
Electrical stimulation for an overactive bladder can reduce the need to urinate as frequently. It is usually a safe and ... Types of electrical stimulation for overactive bladder. The FDA has approved two types of electrical stimulation for OAB: ... Transcutaneous electrical nerve stimulation (TENS) is a modification. of electrical stimulation therapy. The FDA has not ... How well does electrical stimulation help with OAB?. Research indicates that the two FDA-approved types of electrical ...
... by the electrical stimulation of an area at the back of the nose - has shown promising results in initial studies. ... A novel potential approach to treating acute ischemic stroke - by the electrical stimulation of an area at the back of the nose ... Cite this: Electrical Stimulation of Collateral Flow Promising in Acute Stroke - Medscape - May 27, 2019. ... "We saw dramatic evidence of benefit with lower doses of electrical stimulation in patients with cortical strokes," said study ...
... Detailed gene-activity map could pave way for ... First, the researchers emulated each aspect of the treatment in mice - from injury and electrical stimulation to training with ... Electrical stimulation helps paralysed people walk again - and now we know why ... a technique known as epidural electrical stimulation (EES) - could, when combined with intensive training, get people with this ...
Electrical stimulation zaps premature ejaculation. FDA-approved vPatch claims to be the first non-pharmacological, non-numbing ... Virility didnt invent the idea of a medical device providing transcutaneous electrical nerve stimulation (TENS). This ... When its turned on (pun intended), the patch delivers an electric stimulus to the muscles in the area, inhibiting the rhythmic ... technique has been used commercially for many years to provide temporary pain relief by sending small electrical impulses to ...
Medtronics Digestive and Gastrointestinal therapies for Healthcare Professionals.
Electric Cars Electric Leisure & Sea-going Boats and Ships Electric Motors for Electric Vehicles Electric Two-wheelers Electric ... Battery Swapping for Electric Vehicles Charging Infrastructure for Electric Vehicles and Fleets Electric and Fuel Cell Trucks ... Second-life Electric Vehicle Batteries Thermal Management for Electric Vehicles Wireless Charging Market for Electric Vehicles ... Electrical stimulation products and markets. 01 December 2020 by James Hayward. Skin worn or implantable products can be used ...
Transcranial electrical stimulation (tES) is an umbrella term for non-invasive brain stimulation using weak currents. It ... Other: transcranial Random Noise Stimulation (tRNS) with acoustic stimulation (AS) Other: transcranial Random Noise Stimulation ... Transcranial Electrical and Acoustic Stimulation for Tinnitus (tEAS). The safety and scientific validity of this study is the ... Martins ML, Kleinjung T, Meyer M, Raveenthiran V, Wellauer Z, Peter N, Neff P. Transcranial electric and acoustic stimulation ...
Transvaginal Electrical Stimulation for Myofascial Pelvic Pain. The safety and scientific validity of this study is the ... Sessions of electric muscle stimulation will be performed at a frequency of 200 Hz (to induce a passive pelvic floor muscle ... Sessions of electric muscle stimulation will be performed at a frequency of 200 Hz (to induce a passive pelvic floor muscle ... Electrical stimulation with non-implanted devices for stress urinary incontinence in women. Cochrane Database Syst Rev. 2017 ...
Development and Validation of a High Fidelity Finite Element Model of Monopolar Stimulation in the Implanted Guinea Pig Cochlea ... Development and Validation of a High Fidelity Finite Element Model of Monopolar Stimulation in the Implanted Guinea Pig Cochlea ...
In addition, the proposed model was able to predict that stimulation of a seizure focus region is more effective for ... investigated the key factors that determine the size of an effective region in seizure suppression via electrical stimulation. ... First of all, the suppression effect occurred only locally where directly received the stimulation effect in the high noise ... First of all, the suppression effect occurred only locally where directly received the stimulation effect in the high noise ...
Real-time adaptation: the system can modify a number of activation parameters to improve the quality of the stimulation-induced ... Greater muscle selectivity during stimulation: the use of an electrode with multiple fields allows muscles to contract with ... and neuromuscular disease patients at all stages of their rehabilitation process by means of functional electrical stimulation ...
Electrical Stimulation Allows Gene Therapy to Restore Auditory Nerves, Improve Cochlear Implants. April 24th, 2014 Medgadget ... The focusing of electric fields by particular cochlear implant electrode configurations led to surprisingly efficient gene ... This neural remodeling enabled bipolar stimulation via the cochlear implant array, with low stimulus thresholds and expanded ... the tips of the acoustic nerve bundles that the implants stimulate become sickly and ineffective at absorbing the electrical ...
A possible alternative is electrical stimulation with non-implanted devices, whereby an electrical current is delivered through ... compared to other treatments and to different types of electrical stimulation. Finally, we investigated whether electrical ... Adding electrical stimulation to pelvic floor muscle training may not make much difference to cure or improvement of SUI. It is ... Non-invasive electrical stimulation for stress urinary incontinence in women. Review question ...
Review the concepts of upper airway musculature and neuromuscular electrical stimulation to the tongue and understand how the ... The intensity (electrical current) of the stimulation is adjustable within the app on a scale of 1-15; users are instructed to ... Applying the Known Concept of Neuromuscular Electrical Stimulation to the Tongue. The proportion of slow-twitch versus fast- ... Pae EK, Hyatt JP, Wu J, Chien P. Short-term electrical stimulation alters tongue muscle fibre type composition. Archives of ...
... the researchers significantly boosted the memory and mental performance of laboratory mice through electrical stimulation. ... The study, sponsored by the Office of Naval Research (ONR) Global, involved the use of Transcranial Direct Current Stimulation ... A noninvasive technique for brain stimulation, tDCS is applied using two small electrodes placed on the scalp, delivering short ... Original Research: Full open access research for "Anodal transcranial direct current stimulation boosts synaptic plasticity and ...
... slowly ramped stimulation). Secondly, foot responses to various short bursts of stimulation (twitch stimulation) were then used ... The goal of this thesis is to develop an electrode array-based functional electrical stimulation (FES) system for foot drop ... based on an initial search using twitch stimulation, followed by a more focused ramped stimulation search, is suggested as a ... It was identified that the lowest number of incorrectly identified YEs using twitch stimulation was found with a four pulse ...
Communication dynamics in the human connectome shape the cortex-wide propagation of direct electrical stimulation. View ORCID ... Here, we use 2.77 million intracranial EEG recordings, acquired following 29,055 single-pulse electrical stimulations in a ... Communication dynamics in the human connectome shape the cortex-wide propagation of direct electrical stimulation ... Communication dynamics in the human connectome shape the cortex-wide propagation of direct electrical stimulation ...
Alpha-Stim provides sustainable, proven relief from pain, anxiety, depression, or insomnia, using cranial electrical stimulation and neuromodulation.
What is neuromuscular electrical stimulation? (NMES). Neuromuscular electrical stimulation sends electrical impulses to nerves ... The study is an evaluation of a six week intervention of home-based neuromuscular electrical stimulation (NMES) that aims to ...
Saudi Arabia Transcutaneous Electrical Nerve Stimulation Market: Prospects, Trends Analysis, Market Size and Forecasts up to ... 4. Saudi Arabia Transcutaneous Electrical Nerve Stimulation Market by Surgery Procedures. 4.1. Direct Nerve Repair. 4.2. Nerve ... Saudi Arabia Transcutaneous Electrical Nerve Stimulation Market: Prospects, Trends Analysis, Market Size and Forecasts up to ... Transcutaneous Electrical Nerve Stimulation Market Size, Share & Trends Analysis by Product Type (Portable, Table Top), by ...
Devices using TENS (transcutaneous electrical nerve stimulation) technology alleviate pain by sending pulses on the surface of ... transcutaneous electrical nerve stimulation Leading Headlines, Supplier News ...
... for multiple nerve stimulation as maintained by CM ... Transcutaneous electrical nerve stimulation (TENS) device, four ... HCPCS Code E0730 for Transcutaneous electrical nerve stimulation (TENS) device, four or more leads, ... CIGNA [LIST] [*]Transcutaneous Electrical Nerve Stimulation (TENS)A transcutaneous electrical nerve stimulator (TENS) (HCPCS ... HCPCS Code for Transcutaneous electrical nerve stimulation (TENS) device, four or more leads, for multiple nerve stimulation ...
Home , A Back and Neck Support Store , Product Index , TENS/EMS Muscle Stimulation Electrical Muscle Stimulation ... VITAL STIM EMS 2000R - EMS/TENS/Russian Stimulation Compare at $600 $285. VITAL STIM EMS 4000R - EMS/TENS/Russian Stimulation ... Electronic Muscle Stimulation (EMS) is a technologically advanced science that uses very mild electrical current to exercise ... Russian Stimulation Mode: 2500 Hertz @ 50 PPS * Reciprocation: Yes * Pulse Width: 200 microseconds * Ramp Time: 3 Seconds * ...
We have developed a high-throughput system of closed-loop electrical stimulation and optical recording that facilitates the ... We demonstrated that closed-loop imaging and micro-stimulation technology enable the study of neuronal excitation across a ... stimulus selectivity within a given neuron pair is possible in the one-parameter search space by using multiple stimulation ...
Transcutaneous electrical acupoint stimulation (TEAS) for cancer-related fatigue: study protocol for a systematic review and ... Transcutaneous electrical acupoint stimulation (TEAS) for cancer-related fatigue: study protocol for a systematic review and ... Transcutaneous electrical acupoint stimulation (TEAS) for cancer-related fatigue: study protocol for a systematic review and ...
Animals-16 healthy horses that underwent hypoglossal nerve block and 5 healthy horses that underwent electrical stimulation of ... Conclusions and Clinical Relevance-Bilateral electrical stimulation of the thyrohyoideus muscles in horses in this study ... Procedures-Horses underwent bilateral hypoglossal nerve block or electrical stimulation of the thyrohyoideus muscles. Positions ... Bilateral thyrohyoideus muscle stimulation induced significant dorsal movement (mean ± SD change in position, 18.7 ± 6.8 mm) of ...
Background: Neuromuscular electrical stimulation (NMES) has been used as a treatment option in the therapy of dysphagia for ... Neuromuscular electrical stimulation (NMES) aims to restore and enhance the motor function of weak muscles as well as enable ... Zeng Y, Yip J, Cui H, Guan L, Zhu H, Zhang W, Du H, Geng X. Efficacy of neuromuscular electrical stimulation in improving the ... Neuromuscular electrical stimulation (NMES) generally aims to restore and enhance motor function of weak muscles as well as ...
High-frequency Sinusoidal Neurostimulation (BioWave) Versus Transcutaneous Electrical Nerve Stimulation (TENS) for the ...
  • Transcutaneous electrical nerve stimulation (TENS) is a modification of electrical stimulation therapy. (
  • Virility didn't invent the idea of a medical device providing transcutaneous electrical nerve stimulation (TENS). (
  • The country research report on Saudi Arabia transcutaneous electrical nerve stimulation market is a customer intelligence and competitive study of the Saudi Arabia market. (
  • Also, factors that are driving and restraining the transcutaneous electrical nerve stimulation market are highlighted in the study. (
  • The companies and dealers/distributors profiled in the report include manufacturers & suppliers of transcutaneous electrical nerve stimulation market in Saudi Arabia. (
  • The report on Saudi Arabia transcutaneous electrical nerve stimulation market provides a detailed analysis of segments in the market based on surgery procedures, product, and end user. (
  • 1) What is the market size of transcutaneous electrical nerve stimulation market in Saudi Arabia? (
  • 2) What are the factors that affect the growth in transcutaneous electrical nerve stimulation market over the forecast period? (
  • 4) What are the opportunities in Saudi Arabia transcutaneous electrical nerve stimulation market? (
  • 5) What are the modes of entering Saudi Arabia transcutaneous electrical nerve stimulation market? (
  • CIGNA [LIST] [*]Transcutaneous Electrical Nerve Stimulation (TENS)A transcutaneous electrical nerve stimulator (TENS) (HCPCS Code E0720, E0730) and related supplies (HCPCS Code A4595) are considered m. (
  • Scherder, EJA , van Someren, EJ & Swaab, DF 1999, ' Transcutaneous electrical nerve stimulation (TENS) improves the rest-activity rhythm in midstage Alzheimer's disease ', Behavioural Brain Research , vol. 101, pp. 105-107. (
  • Acupuncture, transcutaneous electrical nerve stimulation, and laser therapy in chronic pain. (
  • Phase II Randomized Trial of Acupuncture-Like Transcutaneous Electrical Nerve Stimulation to Prevent Radiation-Induced Xerostomia in Head and Neck Cancer Patients. (
  • Transcutaneous Electrical Nerve Stimulation in Dysphonic Patients: A Systematic Review. (
  • This paper aims to systematically review the application methods and clinical outcomes of transcutaneous electrical nerve stimulation ( TENS ) in the rehabilitation of dysphonic patients . (
  • Half of participants will receive conventional physiotherapy, while the other half will receive core stability exercises and core stability exercises plus transcutaneous electrical nerve stimulation (TENS). (
  • This group will be divided in two: core stability exercises (CSE) plus conventional therapy (CP) and CSE with transcutaneous electrical nerve stimulation (TENS) plus CP. (
  • Clinical Outcome After Low-Level Laser Acupuncture, Microamps Transcutaneous Electrical Nerve Stimulation, and Other Alternative Therapies. (
  • Other treatments are oral contraceptives, transcutaneous electrical nerve stimulation, presacral neurotomy and even hysterectomy [1-3]. (
  • Comparison of the antinociceptive effects induced by electroacupuncture and transcutaneous electrical nerve stimulation in the rat. (
  • TENS involves a battery-powered device that sends electrical impulses through electrodes on the skin surface. (
  • Together, they and their team studied the history of upper airway neuromuscular electrical stimulation (NMES) - what worked, what didn't work - and designed and tested what would eventually become eXciteOSA. (
  • The study is an evaluation of a six week intervention of home-based neuromuscular electrical stimulation (NMES) that aims to strengthen the quadriceps muscles in the legs. (
  • What is neuromuscular electrical stimulation? (
  • Neuromuscular electrical stimulation sends electrical impulses to nerves. (
  • Neuromuscular electrical stimulation (NMES) has been used as a treatment option in the therapy of dysphagia for several years. (
  • Surface neuromuscular electrical stimulation evoked resistance training (NMES-RT) was developed as a strategy to attenuate the process of skeletal muscle atrophy, decrease ectopic adiposity, improve insulin sensitivity and enhance mitochondrial capacity. (
  • Natsume T, Ozaki H, Saito AI, Naito H. Neuromuscular electrical stimulation with blood flow restriction increases serum growth hormone concentration. (
  • Neuromuscular electrical stimulation (NMES) applied in the periphery can elicit strong sensory input that could modulate the excitability of contralateral primary sensorimotor cortex. (
  • NMES has been used in sports medicine, rehabilitation and physiotherapy for decades, with different stimulation patterns targeting endurance versus strength training. (
  • However, due to different stimulation protocols, electrode positioning and various underlying pathological conditions, it was difficult to compare the studies which were identified and it was concluded that more empirical data is needed to fully understand the benefits provided by NMES. (
  • A possible alternative is electrical stimulation with non-implanted devices, whereby an electrical current is delivered through vaginal electrodes. (
  • A noninvasive technique for brain stimulation, tDCS is applied using two small electrodes placed on the scalp, delivering short bursts of extremely low-intensity electrical currents. (
  • We show that stimulus selectivity within a given neuron pair is possible in the one-parameter search space by using multiple stimulation electrodes. (
  • Electromyography is a procedure to continuously monitor and record the muscle's electrical activity using needle electrodes. (
  • The neurologist places electrodes in the scalp and monitors the brain's electrical activity with the EEG . (
  • Acoustic signals in the form of ultrasound offer a promising class of neuromodulation which would be an especially valuable approach because it is non-invasive-no surgical procedure to implant electrodes for stimulation is required. (
  • For the study, 1000 patients with anterior-circulation acute ischemic stroke, not undergoing reperfusion therapy, were randomized to receive active sphenopalatine ganglion stimulation or sham stimulation (control) starting 8 to 24 hours after stroke onset (median 19 hours). (
  • However, it is still difficult to optimize the stimulation conditions for each patient, thereby limiting efforts to improve the efficacy of this therapy. (
  • There was not enough evidence comparing electrical stimulation to other existing treatments such as drug therapy, pelvic floor muscle training plus vaginal cones, surgery, or different forms of electrical stimulation, to provide evidence-based guidance on which would be better, and for which women, in curing or improving SUI or in improving quality of life. (
  • Eighteen studies were identified with varying patient groups, stimulation protocols, electrode placement and therapy settings. (
  • Further research is still necessary in order to clarify which stimulation protocols, parameters and therapy settings are most beneficial for certain patient groups and degrees of impairment. (
  • For Patricia Brooks, the tingling of electrical current running through her leg was preferable to the sting of physical therapy following her total knee replacement. (
  • Brooks, participated in a clinical trial offered at Forbes Regional Hospital to determine whether electrical muscle stimulation (EMS) is as effective as standard physical therapy in helping patients recover from joint replacement surgery. (
  • Energy psychologists believe physical interventions to regulate electrical signals or energy fields can be combined with evidence-based exposure therapy to retrain the brain and help individuals overcome any physical and emotional reactions affecting health and well-being. (
  • Proponents of energy psychology believe the repeated pairing of exposure and meridian point stimulation can lead individuals to experience less hyperarousal when they are exposed to previous triggers of hyperarousal outside of therapy. (
  • I use an integrated approach to care including chiropractic adjustment, manual manipulation and mobilization, neurology based muscle relaxation techniques, dynamic cupping, ultrasound, electrical muscle stimulation, cold laser, instrument assisted soft tissue mobilization (Graston), mechanical diagnosis and therapy (McKenzie), therapeutic exercise and nutritional support for muscles and joints. (
  • The equipment line includes desktop and portable devices that incorporate super pulsed laser, infrared, blue and red light therapy, electrical stimulation, static magnetic field, LaserStim™ with TARGET™ and LaserSweep™ technologies. (
  • It comprises transcranial direct current stimulation (tDCS), which is the most established and used method applying constant direct current, transcranial alternating current stimulation (tACS) with sinusoidal current in a fixed frequency, and finally transcranial random noise stimulation (tRNS), which is a subform of tACS generating a random range of low and high frequency alternating currents. (
  • Researchers at the University of North Carolina investigated the relationship between alpha oscillations and chronic pain in 20 patients, along with possible therapeutic benefits of transcranial alternating current stimulation (tACS), a noninvasive technique that targets specific patterns within brain regions using electrical stimulation. (
  • The study, sponsored by the Office of Naval Research (ONR) Global, involved the use of Transcranial Direct Current Stimulation, or tDCS, on the mice. (
  • Such techniques are based on the neural modulation of brain activity, including the one known as The Transcranianial Direct Current Stimulation (TDCS). (
  • Anodal tDCS using prefrontal stimulation produced significant effects on verbal fluency. (
  • Transcranial direct current stimulation (tDCS) is a brain stimulation technique used to examine causal relationships between brain regions and cognitive functions. (
  • The effects from tDCS are complex, and the extent to which stimulation reliably affects different cognitive domains is not fully understood and continues to be debated. (
  • Next, a series of sub-analyses examined the effects of tDCS on specific tasks and stimulation protocols. (
  • Greater muscle selectivity during stimulation: the use of an electrode with multiple fields allows muscles to contract with greater selectivity. (
  • The focusing of electric fields by particular cochlear implant electrode configurations led to surprisingly efficient gene delivery to adjacent mesenchymal cells. (
  • The goal of this thesis is to develop an electrode array-based functional electrical stimulation (FES) system for foot drop correction. (
  • In the first study a finite element model was used to predict the effects of electrode design on the spatial spread of stimulation selectivity in tissue underlying the cathode. (
  • A single-blinded randomised study of the effects of hydrogel resistivity on discomfort was also conducted in which the discomfort associated with stimulation through a low impedance electrode was compared with that experienced during stimulation with a high impedance electrode. (
  • Our Electro Muscle Stimulation Units include Rubber electrode pads, straps, lead wires, gel, 110V power supply and a complete manual for easy operation. (
  • Next, we found significant effects on specific stimulation protocols (e.g., offline measures, P = 0.002), as well as specific tasks and electrode montages (e.g., verbal fluency measures and left prefrontal cortex, P = 0.035). (
  • This involves a single-use electrode patch stuck to the forehead, which sends small electrical pulses through the skin during sleep. (
  • In addition, a preliminary study in 253 patients (ImpACT-24A) involving sphenopalatine ganglion stimulation showed potential benefit in improving functional outcome compared with a sham control. (
  • Its mission is to improve the quality of life of stroke and neuromuscular disease patients at all stages of their rehabilitation process by means of functional electrical stimulation medical devices. (
  • Functional electrical stimulation-lower extremity cycling (FES-LEC) allows for the activation of 6 muscle groups, which is likely to evoke greater metabolic and cardiovascular adaptation. (
  • Functional electrical stimulation (FES) has been used broadly during rehabilitation and sport injuries to expedite tissue and muscle recovery. (
  • Objective: Functional Electrical Stimulation (FES) for correction of dropped foot has been shown to increase mobility, reduce the incidence of falls and to improve quality of life. (
  • Wide-pulse electrical stimulation to an intrinsic foot muscle induces acute functional changes in forefoot-rearfoot coupling behaviour during walking. (
  • Functional electrical stimulation has been examined as a potential symptomatic treatment for this condition. (
  • One small study showed that this treatment, which uses externally applied electrical stimulation to induce functional movement in weak muscles, can benefit some patients with adrenomyeloneuropathy who have difficulty walking. (
  • It entails surgical placement of an electrical stimulator under the skin that sends pulses to one of the sacral nerve roots in the lower back. (
  • The needle attaches to a device outside the body that sends electrical pulses through the nerve. (
  • In 2018, neuroscientist Grégoire Courtine at the Swiss Federal Institute of Technology in Lausanne and his colleagues showed that delivering electrical pulses to those lower-spine nerves - a technique known as epidural electrical stimulation (EES) - could, when combined with intensive training, get people with this kind of spinal-cord injury walking again 2 . (
  • Electroacupuncture uses thin needles inserted beneath the skin that are attached to a device that sends electric pulses into the body. (
  • There are also behavioral treatments like biofeedback and nerve stimulation, which use electric pulses to help people learn how to manage pain. (
  • The noninvasive option entails passing an electric current through the bladder muscle via an anal or vaginal probe or through a needle that a doctor inserts into the tibial nerve. (
  • The FDA has approved two types of electrical stimulation for OAB: sacral neuromodulation (SN) and posterior tibial nerve stimulation (PTNS). (
  • Counter-intuitively, when EES was switched on in people, nerve-cell activity at the site of stimulation decreased. (
  • This is because the tips of the acoustic nerve bundles that the implants stimulate become sickly and ineffective at absorbing the electrical signals. (
  • This neural remodeling enabled bipolar stimulation via the cochlear implant array, with low stimulus thresholds and expanded dynamic range of the cochlear nerve, determined via electrically evoked auditory brainstem responses. (
  • When an electrical impulse is applied to the motor nerve, it prompts muscle contraction, resulting in an efficient workout with less risk of injury to joints and tendons and without cardiovascular fatigue. (
  • Method: All received common peroneal nerve stimulation, producing dorsiflexion and eversion time to the swing phase of gait using a heel switch. (
  • Percutaneous electrical neural field stimulation (PENFS) of the auricle is similar to PENS, but instead of targeting a single neurovascular bundle, PENFS stimulates the entire ear, covering all auricular branches of the cranial nerves, including the vagus nerve. (
  • EEG (16 channels) of bilateral sensorimotor cortical area and surface EMG of the stroke-affected flexor pollicis brevis were recorded while the subjects performed a 20-second steady hold contraction at 50% maximal voluntary before and after a 40-minute electrical stimulation session on median nerve. (
  • For women with bladder incontinence who haven't been helped by medications or other therapies, Botox injections may help control leakage better than an implanted nerve stimulation device, a new study suggests. (
  • For nerve stimulation during surgeries involving the brain and face. (
  • Research indicates that the two FDA-approved types of electrical stimulation are effective for OAB. (
  • We also investigated whether SUI was cured or improved by adding electrical stimulation to other treatments, compared to other treatments and to different types of electrical stimulation. (
  • After eight weeks of treatment with electroacupuncture - acupuncture involving electrical stimulation - study participants experienced significant symptom and quality-of-life improvements, the study found. (
  • Body tapping involves stimulation of the points on the body also targeted in acupuncture, which are known as meridian points. (
  • The aim of this three-arm randomized study is to evaluate the utility of transvaginal electrical stimulation at a fixed frequency of 200 Hz in women with symptomatic MPP in comparison to the standard, first-line treatment with education, stretching, and low-impact exercise. (
  • Nursing staff without prior training will be taught to deliver this high-frequency transvaginal electrical stimulation (HF-TES) treatment using the device. (
  • MPP subjects who meet inclusion/exclusion criteria will be approached for study inclusion and randomized 2:1 to high frequency transvaginal electrical stimulation (HF-TES) vs. usual care. (
  • Further, to evaluate the electrical activity generated during FES application using surface electromyography and its relation to time to fatigue (TTF) at each frequency. (
  • Electrical stimulation with non-implanted devices aims to inhibit contractions of the detrusor muscle, potentially reducing urinary frequency and urgency. (
  • In this study the acute effects of high-frequency, low-intensity wide-pulse electrical stimulation (WPS) over an intrinsic muscle on subsequent foot function during walking was assessed in healthy participants. (
  • Alternating low frequency stimulation of medial septal and commissural fibers induces NMDA-dependent, long-lasting potentiation of hippocampal synapses in urethane-anesthetized rats med. (
  • ABSTRACT Objective: To evaluate the effect of abdominal electrical stimulation (EE) on bowel movement frequency and feces consistency and expelled amount in people with constipation due to spinal cord injuries (SCI). (
  • In conclusion, we confirmed the possibility of a computational model as a simulation tool to analyze the efficacy of deep brain stimulation (DBS) and investigated the key factors that determine the size of an effective region in seizure suppression via electrical stimulation. (
  • Recently, deep brain stimulation (DBS) for refractory epilepsy has been receiving attention as an innovative treatment method. (
  • Transcranial electrical stimulation (tES) is an umbrella term for non-invasive brain stimulation using weak currents. (
  • Skin worn or implantable products can be used to apply electrical signals to the body in order to achieve a therapeutic effect. (
  • Therapeutic stimulation of neurons with electrical energy or chemicals-and potentially with acoustic waves-can amplify or dampen neuronal impulses in the brain or body. (
  • The behavioral effects of direct electrical stimulation of the cingulum bundle, a white matter tract in the brain, were confirmed in two other epilepsy patients undergoing diagnostic monitoring. (
  • The first group received electroacupuncture (low-intensity electrical stimulation on different needle points in the body) on their inner wrists and below their knees, and 70 percent of the participants saw a reduction in blood pressure, an improvement that lasted over a month. (
  • We saw dramatic evidence of benefit with lower doses of electrical stimulation in patients with cortical strokes," said study author Jeffrey Saver, MD, Ronald Reagan UCLA Medical Center, Los Angeles, California. (
  • Greater gamma-band coherence after repetitive electrical stimulation might indicate enhanced cortical activity level and sensorimotor integration during voluntary motor task. (
  • Cortical electrical stimulation involves stimulating the cortical region of the brain. (
  • Results were indicative of a superior efficacy of combined electrical and acoustic approaches, while large-scale controlled studies have not been performed. (
  • Treatments for MPP using electrical stimulation to induce muscle fatigue have proven efficacy at reducing pain, improving circulation, and promoting tissue healing, but have proven difficult to implement in gynecologic practice. (
  • This study aims to evaluate the feasibility of a randomised controlled trial to test the efficacy and cost-effectiveness of delivering early intensive electrical stimulation (ES) to prevent post-stroke complications in the paretic upper limb. (
  • The Food and Drug Administration (FDA) has approved an invasive type of electrical stimulation that requires surgery and a noninvasive type that does not require surgery. (
  • Electrical stimulation can be noninvasive or invasive. (
  • Electrical stimulation for an overactive bladder (OAB) involves sending an electrical current to the nerves that play a role in bladder function. (
  • Keep reading to learn more about electrical stimulation for an overactive bladder and the different types, as well as their effectiveness and safety. (
  • Several options exist for managing overactive bladder (OAB), including electrical stimulation (ES) with non-implanted devices, conservative treatment and drugs. (
  • We examined whether chloride salts of metals in HM alloys can elicit responses or modify reactivity to methacholine (MCh) or responses to electric field stimulation (EFS) in guinea pig tracheal strips. (
  • This technique has been used commercially for many years to provide temporary pain relief by sending small electrical impulses to the affected area. (
  • EMS uses electrical impulses to simulate the body's natural process of voluntary muscular contractions. (
  • We investigated whether electrical stimulation was better than no treatment at all or better than other available treatments for curing or improving stress urinary incontinence (SUI) symptoms in women. (
  • We found that few women reported adverse effects with electrical stimulation, but there was not enough reliable evidence comparing electrical stimulation to other treatments to know more about its safety. (
  • While we found evidence indicating that electrical stimulation may be better than no treatment, we did not find enough well-designed trials with enough women to fully answer our review questions, so we do not yet know if ES is better or worse than other treatments. (
  • The current evidence base indicated that electrical stimulation is probably more effective than no active or sham treatment, but it is not possible to say whether ES is similar to PFMT or other active treatments in effectiveness or not. (
  • The order of treatments was randomized between patients (so some received the control first, and others the tACS first, but were not informed which), and the electrical activity and pain reporting were recorded after each session, which were separated by two weeks. (
  • For an in-depth discussion of chronic pain, depression, why the two often coexist, and possible treatments besides electrical stimulation, check out Emily Orwell's recent article . (
  • Treatment plans can justifiably include treatments like spinal manipulation, electrical stimulation and exercise, all therapies supported by ODG and other treatment guidelines. (
  • To help rebuild his strength, balance and endurance, Jason's physical therapists combined proven treatments, exercises and advanced technologies, such as electrical stimulation. (
  • In the first approach foot responses during a slowly ramped increase in stimulus current to each of 49 YEs were measured to directly identify suitable VE(s) (slowly ramped stimulation). (
  • Secondly, foot responses to various short bursts of stimulation (twitch stimulation) were then used to predict the subsets containing the best VEe s) identified using the first method. (
  • Use of electric potential or currents to elicit biological responses. (
  • When it's turned on (pun intended), the patch delivers an electric stimulus to the muscles in the area, inhibiting the rhythmic contractions leading to orgasm. (
  • Electrical Muscle Stimulators have also been used for the relaxation of muscle spasms, increasing range of motion, reduction and prevention of muscle atrophy, reeducation of muscles, increasing local blood circulation and relief from minor pain (joint pains, muscle aches, etc.) and stress. (
  • Electronic Muscle Stimulation (EMS) is a technologically advanced science that uses very mild electrical current to exercise your muscles and give you tone, definition, and a figure you can easily maintain and sculpt in the comfort of your home environment. (
  • In panel C, mean baseline positions of laryngeal sites of horses are indicated by squares, mean positions following stimulation of thyrohyoideus muscles of horses in the present study are indicated by circles, and mean positions following placement of a prosthetic suture for horses in another study 15 are indicated by triangles. (
  • Findings support recommendations that stimulation at 50Hz may be most optimal for small muscles of predominantly type I fiber composition while stimulation at 10Hz may be most optimal for large muscles of predominantly type II fiber composition to prolong TTF. (
  • We can also train our pelvic floor muscles through lifestyle changes, by using electrical stimulation, by using internal pelvic floor weights. (
  • When the researchers used tFUS to emit repeated bursts of ultrasound stimulation directly at excitatory neurons, they observed an elevated impulse rate, or spike. (
  • Electromyography (EMG), or the recording of electrical phenomena resulting from muscle stimulation and contraction, has long proven a valuable tool for the assessment of muscular loads and stresses in biomedical research. (
  • We saw a very clear inverse U-shaped dose-response curve, with patients who received low to medium doses of stimulation having better outcomes, whereas patients with high stimulation did only as well as control," he said. (
  • Without sufficiently powered trials measuring clinically important outcomes, such as subjective assessment of urinary incontinence, we cannot draw robust conclusions about the overall effectiveness or cost-effectiveness of electrical stimulation for stress urinary incontinence in women. (
  • Appropriate knowledge of the stimulation parameters is key to maximizing the outcomes of electrical stimulation training in persons with SCI. (
  • Herein we describe biomineralized conducting polymer-based bone tissue scaffolds that facilitate the electrical stimulation of human mesenchymal stem cells, resulting in enhancement of their differentiation towards osteogenic outcomes. (
  • We anticipate that our findings will have implications for research on macroscale neural information processing and the design of brain stimulation paradigms. (
  • We have developed a high-throughput system of closed-loop electrical stimulation and optical recording that facilitates the rapid characterization of extracellular stimulus-evoked neural activity. (
  • The use of a cryogenic surface coil in a small animal 9.4T system provided the sensitivity required for detection and quantitative analysis of hemodynamic changes caused by neural activity in the mouse brain in response to electrical forepaw stimulation at different amplitudes. (
  • Percutaneous electrical neural stimulation (PENS) is an evidence-based treatment option for pain conditions that involves electrical current stimulation through needles inserted into the skin. (
  • As the comprehensive slowly ramped stimulation search is too slow to be used in clinical practice, a two stage process, based on an initial search using twitch stimulation, followed by a more focused ramped stimulation search, is suggested as a future approach. (
  • We demonstrated that closed-loop imaging and micro-stimulation technology enable the study of neuronal excitation across a large parameter space, which is requisite for controlling neuronal activation in next generation clinical solutions. (
  • A system involving the electrical iontophoretic introduction of free silver ions into human wounds for their antibiotic effect has been in clinical use since 1975. (
  • Saver presented results of a 1000-patient study of sphenopalatine ganglion stimulation (ImpACT-24B) at the 5th European Stroke Organisation Conference (ESOC) 2019. (
  • The study was also able to investigate a dose response, as different doses of stimulation were delivered to individual patients. (
  • A pilot study conducted by Shekhawat and colleagues in 2015 tested the effects of simultaneous electrical and acoustic stimulation. (
  • In this paper, we identified factors that can affect seizure suppression via electrical stimulation by an integrative study based on experimental and computational approach. (
  • Indeed, a 2007 study applied electrical stimulation to the genioglossus of New Zealand white rabbits and found that the proportion of slow-twitch fibers almost doubled over a period of seven days. (
  • In a breakthrough study that could improve how people learn and retain information, researchers at the Catholic University Medical School in Rome significantly boosted the memory and mental performance of laboratory mice through electrical stimulation. (
  • Here, we use 2.77 million intracranial EEG recordings, acquired following 29,055 single-pulse electrical stimulations in a total of 550 individuals, to study inter-areal communication in the human brain. (
  • In the feasibility study, ten people diagnosed with mild cognitive impairment used goggles and headphones that provided light/sound stimulation at home for an hour every day. (
  • A recent study in the journal Nature, by scientists at the Swiss research center NeuroRestore, identified a type of neuron activated by electrical stimulation of the spinal cord, allowing nine patients with chronic spinal cord injury to walk again. (
  • For this systematic review, a selective literature research in PubMed has been carried out on 5th May 2021 using the terms electrical stimulation AND dysphagia and screened for inclusion criteria by two reviewers in Rayyan. (
  • First, the researchers emulated each aspect of the treatment in mice - from injury and electrical stimulation to training with a purpose-built robotic support for stability. (
  • We found 56 trials (involving a total of 3781 women, all with stress urinary incontinence but some with urgency urinary incontinence as well) comparing electrical stimulation to no treatment or to any other available treatment. (
  • For cure or improvement of SUI, electrical stimulation was probably better than no active or sham treatment. (
  • There is some evidence to support the use of electrical stimulation for stress urinary incontinence in women, but we are still very uncertain about the full potential of this treatment because of the low quality of the existing evidence. (
  • We have evaluated an alternative treatment, electrical stimulation (ES) with non-implanted devices, which aims to improve pelvic floor muscle function to reduce involuntary urine loss. (
  • To assess the effects of electrical stimulation with non-implanted devices, alone or in combination with other treatment, for managing stress urinary incontinence or stress-predominant mixed urinary incontinence in women. (
  • Furthermore, while the literature is limited for use of electric stim and other passive therapies there are a few studies which do support treatment. (
  • Both papers suggest that electrical stimulation is a treatment option in the acute and chronic phases of treatment. (
  • Electrical stimulation appeared to be more effective than both no treatment and drug treatment for OAB. (
  • The effects of stimulation were observed in an epilepsy patient undergoing diagnostic monitoring for seizure diagnosis. (
  • Mai 2021 wurde eine Literaturrecherche in Pubmed mit den Suchkriterien electrical stimulation AND dysphagia durchgef hrt und anschlie end in Rayyan von zwei Bewertern auf ihre Einschlusskriterien berpr ft. (
  • the system can modify a number of activation parameters to improve the quality of the stimulation-induced movement. (
  • More recently the use of a newly developed silvered nylon fabric has been found to have similar results without the need for electrical parameters. (
  • Optional Russian Stimulation Prescription Required - Russian Stimualtion provides a deeper and stronger muscle contraction in addition to the standard EMS mode. (
  • Clips are attached to the needles with wires that connect to an electric stimulation machine, sending a fine micro-current to stimulate muscle contraction and relieve stagnation and weakness within the area of injury. (
  • The researchers observed no unanticipated implantation- or stimulation-related adverse events. (
  • Animal studies have shown that sphenopalatine ganglion stimulation up to 24 hours after the onset of stroke preserved the penumbra, reduced cerebral infarct volume, increased neuronal survival, and preserved the blood-brain barrier leading to reduced cerebral edema and improved neurologic outcome. (
  • Among these patterns are alpha oscillations, waves of electrical activity that arise from the collective firing of many brain cells. (
  • Reality is an interpretation of the electric brain 'high' on stimulation or neuro-plasticity. (
  • Specific to energy psychology is the theory that stimulation of meridian points can send signals to the brain to help reduce hyperarousal. (
  • Other than needles, practitioners may also use heat or electrical stimulation to stimulate the same points in the body. (
  • Electrical stimulation intends to inhibit these contractions to decrease the number of times a person needs to urinate. (
  • The aim behind our proposed approach, similar to the bimodal approaches above, is to couple the effects of tRNS and acoustic stimulation (AS) for better temporary tinnitus suppression and possible reversal of maladaptive neuroplasticity related to tinnitus. (
  • We aim at targeting the (bilateral) auditory cortex with tRNS as in former studies and combine it with white noise (WN) stimulation. (
  • Activation was observed consistently bilateral despite unilateral stimulation of the forepaw. (
  • Results indicated that the VL required a greater stimulation amplitude to generate the FES-induced initial force and generated quicker TTF than the APB. (
  • The maximum BOLD amplitude of both signal components correlated strongly with the stimulation amplitude. (
  • Analysis of the dynamic behavior of the somatosensory 'fast' BOLD component revealed a decreasing signal decay rate constant k(off) with increasing maximum BOLD amplitude (and stimulation amplitude). (
  • An orthopedic surgeon/IME recommended a denial for all electrical stimulation (EMS) by stating that "according ODG electrical stimulation is experimental therefore not medically necessary or eligible for reimbursement. (