A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections.
A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Infections with bacteria of the genus ACINETOBACTER.
A genus of gram-negative bacteria of the family MORAXELLACEAE, found in soil and water and of uncertain pathogenicity.
Substances that reduce the growth or reproduction of BACTERIA.
Therapy with two or more separate preparations given for a combined effect.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
The development of systems to prevent accidents, injuries, and other adverse occurrences in an institutional setting. The concept includes prevention or reduction of adverse events or incidents involving employees, patients, or facilities. Examples include plans to reduce injuries from falls or plans for fire safety to promote a safe institutional environment.
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Efforts to reduce risk, to address and reduce incidents and accidents that may negatively impact healthcare consumers.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A species of gram-negative, aerobic bacteria, commonly found in the clinical laboratory, and frequently resistant to common antibiotics.
Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
Semisynthetic, broad-spectrum, AMPICILLIN derived ureidopenicillin antibiotic proposed for PSEUDOMONAS infections. It is also used in combination with other antibiotics.
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
Absence of urine formation. It is usually associated with complete bilateral ureteral (URETER) obstruction, complete lower urinary tract obstruction, or unilateral ureteral obstruction when a solitary kidney is present.
Infections by bacteria, general or unspecified.
A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Infection within the PERITONEAL CAVITY. A frequent cause is an ANASTOMOTIC LEAK following surgery.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.
Hospital facilities which provide care for newborn infants.
An infant during the first month after birth.
Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
A specialty concerned with the diagnosis and treatment of foot disorders and injuries and anatomic defects of the foot.
Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
Anatomical and functional disorders affecting the foot.
The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.
Invasion of the site of trauma by pathogenic microorganisms.
Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.
Inflammation of the lung parenchyma that is caused by bacterial infections.
Infection of the lung often accompanied by inflammation.
A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.
A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.
Suleyman G, Zervos MJ (2016). "Safety and efficacy of commonly used antimicrobial agents in the treatment of enterococcal ... ISBN 978-1-4511-1221-4. Akova M (January 2008). "Sulbactam-containing beta-lactamase inhibitor combinations". Clinical ... Bacterial meningitis; an aminoglycoside can be added to increase efficacy against Gram-negative meningitis bacteria. ... Its spectrum of activity is enhanced by co-administration of sulbactam, a drug that inhibits beta lactamase, an enzyme produced ...
... and the large amount of time and number of people that will be needed for appropriate trials for safety and efficacy of the ... Treatment with ampicillin/sulbactam, amoxicillin/clavulanic acid, or clindamycin is appropriate if deep oropharyngeal abscesses ... Falagas ME, Vouloumanou EK, Matthaiou DK, Kapaskelis AM, Karageorgopoulos DE (2008). "Effectiveness and safety of short-course ...
There is not enough reliable evidence of efficacy and safety to support this indication as a routine use. Linezolid has been ... In a 2004 open-label study, it was as effective as ampicillin/sulbactam and amoxicillin/clavulanic acid, and far superior in ... Jaksic B, Martinelli G, Perez-Oteyza J, Hartman CS, Leonard LB, Tack KJ (March 2006). "Efficacy and safety of linezolid ... von der Lippe B, Sandven P, Brubakk O (February 2006). "Efficacy and safety of linezolid in multidrug resistant tuberculosis ( ...
A vacuole at the centre of the bacterium makes it resemble a "safety pin" when Gram stained. The bacteria emit a strong soil ... Major hurdles of the vaccines are limited efficacy in animal models, establishing the best method of vaccine administration in ... No differences are seen between using cefoperazone/sulbactam or ceftazidime to treat melioidosis, as both show similar death ... Meropenem, imipenem, and the cefoperazone-sulbactam combination (Sulperazone) are also effective. Intravenous amoxicillin- ...
The development of penicillin led to renewed interest in the search for antibiotic compounds with similar efficacy and safety.[ ... Beta-lactamase inhibitors, such as clavulanic acid and sulbactam[138]. Metabolic stimuli such as sugar can help eradicate a ... In addition, the oral and IV administration of phages for the eradication of bacterial infections poses a much higher safety ... Health advocacy messages such as this one encourage patients to talk with their doctor about safety in using antibiotics. ...
... antibiotic commonly used with an aminoglycoside retains similar levels of drug safety and efficacy as other antibiotic ... or Haemophilus influenzae, the combination of tazobactam (which shares a similar structure to sulbactam, another β-lactamase ... The inclusion of a β-lactamase inhibitor does not always increase drug efficacy. Some bacteria may produce certain types of β- ... March 2001). "Efficacy and tolerability of piperacillin/tazobactam versus ceftazidime in association with amikacin for treating ...
On July 27, 2020, the companies announced the start of a global (except China) Phase II-III safety and efficacy clinical study ... cefoperazone/sulbactam), an antibiotic used for the treatment of urinary tract infections, which had $618 million in 2020 ... efficacy and safety of fluconazole and nystatin". J Paediatr Child Health. 48 (9): 846-51. doi:10.1111/j.1440-1754.2012.02543.x ... The American Academy of Neurology rates it as having unproven efficacy, while the Canadian Headache Society and the European ...
The safety and efficacy of amikacin liposome inhalation suspension, an inhaled treatment taken through a nebulizer, was ... or ampicillin/sulbactam Meningitis: for meningitis by E. coli, as an adjunct to imipenem for meningitis caused by Pseudomonas, ...
"Safety Alerts for Human Medical Products - Intraocular Injections of a Compounded Triamcinolone, Moxifloxacin, and Vancomycin ( ... Thus, peak serum levels have not been shown to correlate with efficacy or toxicity; indeed, concentration monitoring is ... Safety in pregnancy is not clear, but no evidence of harm has been found,[3][6] and it is likely safe for use when ... pharmacokinetics and clinical efficacy". Current Opinion in Investigational Drugs. 7 (8): 740-9. PMID 16955686.. ...
Study Evaluating the Safety and Efficacy of Piperacillin/Tazobactam and Ampicillin/Sulbactam in Patients With Diabetic Foot ... An Open-label, Randomized Study Comparing the Efficacy and Safety of Piperacillin/Tazobactam and Ampicillin/Sulbactam ... Phase IV Open-Label Foot Infection Study is being conducted to generate comparative Efficacy and Safety data in Diabetic ... The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study ...
Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin ... A Multicenter, Randomized, Open-Label Comparison of the Safety And Efficacy of Tigecycline With That of Ampicillin-Sulbactam or ... Drug: ampicillin-sulbactam Ampicillin-sulbactam: 1.5 g (1 g ampicillin plus 0.5 g sulbactam) to 3 g (3 g ampicillin plus 1 g ... The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ...
Efficacy and safety of the fixed dose combination of cefepime and sulbactam. ... clinical trial to assess efficacy and safety of the fixed dose combination of cefepime and sulbactam in complicated upper and ... 1. To study the efficacy of fixed dose combination of cefepime and sulbactam injections in in complicated upper and lower tract ... Cefepime, sulbactam Primary outcome measure. Improvement in clinical and laboratory parameters, measured on day 0, day 3 and ...
T.E.A. Study: Three days Ertapenem vs three days Ampicillin-sulbactam). ... randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin-Sulbactam 3 days in the ... randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin-Sulbactam 3 days in the ... reduced clinical efficacy, and above all, the increased emergence of antibiotic-resistant pathogens. Ampicillin-Sulbactam is a ...
... reduced clinical efficacy, and above all, the increased emergence of antibiotic-resistant pathogens. Ampicillin-Sulbactam is a ... randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin - Sulbactam 3 days in the ... The efficacy of a 3-day treatment regimen of Ampicillin-Sulbactam (AS 3 g × 3/day administered intravenously) is compared to a ... Basoli G: A prospective, randomized, double-blind, multicenter, controlled clinical study to compare the efficacy and safety of ...
... 만삭 신생아에서 아목시실린-설박탐 복합제제와 암피실린-설박탐 ... The purpose of this study was to compare the efficacy and safety of amoxicillin-sulbactam to ampicillin-sulbactam in treating ... Efficacy and Safety of Amoxicillin-sulbactam and Ampicillin-sulbactam in Full Term Neonates.. ... CONCLUSION: Amoxicillin-sulbactam was as effective and safe as ampicillin-sulbactam for whom neonatal sepsis was suspected. ...
Comparative analysis of safety and efficacy of cefotaxime/sulbactam verses piperacillin/tazobactam combinations in the ... Comparative analysis of safety and efficacy of cefotaxime/sulbactam verses piperacillin/tazobactam combinations in the ... The objective of this study was to compare efficacy and safety Cefotaxime/ Sulbactam (CTS) and Piperacillin/ Tazobactam (PT) ...
Ampicillin and Sulbactam) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and ... and corresponds to 200 mg ampicillin/100 mg sulbactam per kg per day. The safety and efficacy of UNASYN administered via ... and corresponds to a range of 1 g ampicillin/0.5 g sulbactam to 2 g ampicillin/1 g sulbactam. The total dose of sulbactam ... Data from a controlled clinical trial conducted in pediatric patients provided evidence supporting the safety and efficacy of ...
... and corresponds to 200 mg ampicillin/100 mg sulbactam per kg per day. The safety and efficacy of ampicillin and sulbactam for ... AMPICILLIN AND SULBACTAM- ampicillin and sulbactam injection, powder, for solution AMPICILLIN AND SULBACTAM- ampicillin and ... SULBACTAM SODIUM (UNII: DKQ4T82YE6) (SULBACTAM - UNII:S4TF6I2330) SULBACTAM. 0.5 g in 20 mL. ... SULBACTAM SODIUM (UNII: DKQ4T82YE6) (SULBACTAM - UNII:S4TF6I2330) SULBACTAM. 1 g in 20 mL. ...
1986). "Efficacy and safety of sequential treatment of parenteral sulbactam/ampicillin and oral sultamicillin for skeletal ... Ampicillin/sulbactam is a combination of the common penicillin-derived antibiotic ampicillin and sulbactam, an inhibitor of ... The recommended adult dose of ampicillin/sulbactam is 1.5 grams (1g ampicillin sodium plus 0.5g sulbactam sodium) to 3.0 grams ... Skeletal formula of sulbactam. Skeletal formula of sultamicillin, highlighting ampicillin in blue and sulbactam in red ...
... ampicillin/sulbactam). Includes common and rare side effects information for consumers and healthcare professionals. ... Blomqvist M, Hedtrom SA "The clinical efficacy and safety of bacampicillin twice daily in comparative studies." J Int Med Res ... Check with your doctor or nurse immediately if any of the following side effects occur while taking ampicillin / sulbactam:. ... Unasyn (ampicillin-sulbactam)." Roerig Division, New York, NY. 3. Ramakrishnan K, Scheid DC "Diagnosis and management of acute ...
Description of the drug Ampicillin Sodium/Sulbactam Sodium. - patient information, description, dosage and directions. What is ... Safety and efficacy not established.. Hypersensitivity. Reactions range from mild to life-threatening. Use cautiously in ... IV/IM 1.5 to 3 g every 6 h, not to exceed 4 g/day sulbactam (1.5 g of product contains 0.5 g sulbactam). ... 2 g ampicillin sodium per 1 g sulbactam sodium)- Powder for injection 10 g (10 g ampicillin sodium per 5 g sulbactam sodium) ...
Efficacy and safety of ampicillin/sulbactam and cefuroxime in the treatment of serious skin and skin structure infections in ...
Suleyman G, Zervos MJ (2016). "Safety and efficacy of commonly used antimicrobial agents in the treatment of enterococcal ... ISBN 978-1-4511-1221-4. Akova M (January 2008). "Sulbactam-containing beta-lactamase inhibitor combinations". Clinical ... Bacterial meningitis; an aminoglycoside can be added to increase efficacy against Gram-negative meningitis bacteria. ... Its spectrum of activity is enhanced by co-administration of sulbactam, a drug that inhibits beta lactamase, an enzyme produced ...
Efficacy and safety of moxifloxacin in uncomplicated pelvic inflammatory disease: the MONALISA study. Br J Obstet Gynaecol 2010 ... Randomized comparison of ampicillin-sulbactam to cefoxitin and doxycycline or clindamycin and gentamicin in the treatment of ... Efficacy and safety of famciclovir for treating mucocutaneous herpes simplex infection in HIV-infected individuals. AIDS 2000; ... Efficacy and safety of azithromycin as monotherapy or combined with metronidazole compared with two standard multidrug regimens ...
Betrosian AP, Frantzeskaki F, Xanthaki A, Douzinas EE (2008) Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin ... Corbella X, Ariza J, Ardanuy C et al (1998) Efficacy of sulbactam alone and in combination with ampicillin in nosocomial ... Vidal L, Gafter-Gvili A, Borok S, Fraser A, Leibovici L, Paul M (2007) Efficacy and safety of aminoglycoside monotherapy: ... Rodríguez-Hernández MJ, Cuberos L, Pichardo C et al (2001) Sulbactam efficacy in experimental models caused by susceptible and ...
Betrosian AP, Frantzeskaki F, Xanthaki A, Douzinas EE (2008) Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin ... Florescu DF, Qiu F, McCartan MA, Mindru C, Fey PD, Kalil A (2012) What is the efficacy and safety of colistin for the treatment ... Cheng C-Y, Sheng W-H, Wang J-T, Chen Y-C, Chang S-C (2010) Safety and efficacy of intravenous colistin (colistin ... Duraković N, Radojčić V, Boban A, Mrsić M, Sertić D, Serventi-Seiwerth R, Nemet D, Labar B (2011) Efficacy and safety of ...
Kohno S, Tateda K, Mikamo H, Kadota J, Niki Y, Itamura R. Efficacy and safety of intravenous sulbactam/ampicillin 3 g 4 times ... The purpose of this trial is to evaluate the clinical efficacy and safety in Japanese adult subjects with community acquired ... A Multicenter, Unblinded, Non-Comparative Study Of Unasyn-S 12 G/Day Evaluating The Safety And Efficacy In Japanese Adult ... Drug: ampicillin sodium/sulbactam sodium ampicillin sodium/sulbactam sodium is administered 12g/day (3 g four times a day) ...
Wise R: The efficacy and safety of piperacillin/tazobactam in the therapy of bacteraemia. J Antimicrob Chemother 1993; 31 ( ... Ishibashi T, Harada Y, Takamoto M et al.: Clinical efficacy of sulbactam/ampicillin in comparison with cefotiam in the ... Wise R: The efficacy and safety of piperacillin/tazobactam in the therapy of bacteraemia. J Antimicrob Chemother 1993; 31 ( ... Alvart R: An open multicentre study to compare the efficacy and safety of sultamicillin with that of cefuroxime axetil in acute ...
... clinicaltrials.gov To assess the efficacy and safety of oral moxifloxacin compared to oral levofloxacin plus oral metronidazole ... The purpose of this trial is to determine the efficacy and safety of Moxifloxacin in comparison to Sulbactam/Ampicillin in the ... To assess the efficacy and safety of oral moxifloxacin compared to oral levofloxacin plus oral metronidazole in uncomplicated ... Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel ...
Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant ... Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant ... Safety and efficacy of colistin in Acinetobacter and Pseudomonas infections: a prospective cohort study. Intensive Care Med. ... Efficacy and safety of colistin in the treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in patients ...
... emphasize the importance of a team approach in managing inpatients with diabetic foot disorders and investigate the efficacy of ... The safety and efficacy of daptomycin for the treatment of complicated skin and skin-structure infections. Clin Infect Dis. ... Lipsky and colleagues compared IV and oral linezolid with IV ampicillin-sulbactam and oral amoxicillin-clavulanate in 371 ... Efficacy and safety of IV/PO moxifloxacin and IV piperacillin/tazobactam followed by PO amoxicillin/clavulanic acid in the ...
Kohno S, Tateda K, Mikamo H, Kadota J, Niki Y, Itamura R. Efficacy and safety of intravenous sulbactam/ampicillin 3 g 4 times ... The purpose of this trial is to evaluate the clinical efficacy and safety in Japanese adult subjects with community acquired ... The purpose of this trial is to evaluate the clinical efficacy and safety in Japanese adult subjects with community acquired ... A Multicenter, Unblinded, Non-Comparative Study Of Unasyn-S 12 G/Day Evaluating The Safety And Efficacy In Japanese Adult ...
Safety and efficacy analysis. Sohil P Makwana Manish N Solanki Ram K Dikshit. National Journal of Physiology, Pharmacy and ... Cefoperazone + sulbactam versus cefotaxime + sulbactam combination therapy for the treatment of complicated urinary tract ... Early laparoscopic cholecystectomy in acute cholecystitis: safety and advantages. Gopal S. Bhargava, Harmandeep Singh, Jagpreet ...
Hence, the efficacy and safety of an orally administered less expensive antibiotic should also be explored. ... The women received ampicillin-sulbactam IV or normal saline as placebo. The trial was classified as having a low risk of bias ... It should be noted that ampicillin-sulbactam is an expensive drug, especially if it is to be given prophylactically to all ... This Cochrane (10) review aimed to evaluate the efficacy and side-effects of the use of prophylactic antibiotics during labour ...
Comparison of safety and efficacy of Levofloxacin plus Colistin regimen with Levofloxacin plus high dose Ampicillin/Sulbactam ... Comparison of Intravenous Ampicillin-sulbactam Plus Nebulized Colistin with Intravenous Colistin Plus Nebulized Colistin in ...
... and corresponds to 200 mg ampicillin/100 mg sulbactam per kg per day. The safety and efficacy of Unasyn administered via ... and corresponds to a range of 1 g ampicillin/0.5 g sulbactam to 2 g ampicillin/1 g sulbactam. The total dose of sulbactam ... Data from a controlled clinical trial conducted in pediatric patients provided evidence supporting the safety and efficacy of ... Sulbactam sodium is a derivative of the basic penicillin nucleus. Chemically, sulbactam sodium is sodium penicillinate sulfone ...
Sulbactam/Durlobactam. NCT03445195. II. Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of ... Sulbactam/Durlobactam/Imipinem/Cilastatin. NCT03894046. III. Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam ... A phase III clinical trial is currently being undertaken to evaluate the efficacy and safety of intravenous sulbactam- ... Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria ...
Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant ... Corbella X, Ariza J, Ardanuy C, Vuelta M, Tubau F, Sora M, Pujol M, Gudiol F. Efficacy of sulbactam alone and in combination ... Nevertheless, favorable clinical outcomes have been reported with sulbactam, or a combination of sulbactam and other ... one small-scale prospective study showed the efficacy and safety of high dose, extended-interval colistin in critically ill ...
Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder.? The corresponding mean peak ... serum levels for sulbactam range from 48 to 88 mcg/mL and 21 to 40 mcg/mL, ponstel cost with insurance formidably respectively ...
  • UNASYN is an injectable antibacterial combination consisting of the semisynthetic antibacterial ampicillin sodium and the beta-lactamase inhibitor sulbactam sodium for intravenous and intramuscular administration. (rxlist.com)
  • Sulbactam sodium is a derivative of the basic penicillin nucleus. (rxlist.com)
  • UNASYN, ampicillin sodium/sulbactam sodium parenteral combination, is available as a white to off-white dry powder for reconstitution. (rxlist.com)
  • UNASYN dry powder is freely soluble in aqueous diluents to yield pale yellow to yellow solutions containing ampicillin sodium and sulbactam sodium equivalent to 250 mg ampicillin per mL and 125 mg sulbactam per mL. (rxlist.com)
  • 1.5 g of UNASYN (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt) parenteral contains approximately 115 mg (5 mEq) of sodium. (rxlist.com)
  • 1.5 g of Ampicillin and Sulbactam for Injection, USP (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt) parenteral contains approximately 115 mg (5 mEq) of sodium. (nih.gov)
  • [1] Sulbactam sodium is also a derivative of 6-aminopenicillanic acid. (bingj.com)
  • The purpose of this trial is to evaluate the clinical efficacy and safety in Japanese adult subjects with community acquired pneumonia receiving ampicillin sodium/sulbactam sodium, 12g/day (3 g four times a day ) IV. (clinicaltrials.gov)
  • Known or suspected hypersensitivity or intolerance to ampicillin sodium/sulbactam sodium, other penicillins, or cephems. (pfizer.com)
  • Unasyn pharmacy bulk package is a vial containing a sterile preparation of ampicillin sodium and sulbactam sodium for parenteral use that contains many single doses. (drugs.com)
  • Each 1.5 g vial contains: 1.5 g of ampicillin and sulbactam for injection (equivalent to 1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt). (drugsdb.eu)
  • The following table lists the NDCs and labelers of Ampicillin Sodium and Sulbactam Sodium: NDC Trade Name. (devifirda.ml)
  • Ampicillin and sulbactam for injection is a sterile, injectable antibacterial combination, consisting of the semisynthetic antibiotic ampicillin sodium and the beta. (devifirda.ml)
  • Comparative evaluation of efficacy and safety of etodolac and diclofenac sodium injection in patients with postoperative orthopedic pain. (ipca.com)
  • The generic name of Unasyn is ampicillin sodium and sulbactam sodium. (ndclist.com)
  • AMPICILLIN/SULBACTAM (UNASYN ®) The authors make no claims of the accuracy of the information contained. (nudecam.ml)
  • Ampicillin and sulbactam are the active ingredients in the brand-name intravenous antibiotic called Unasyn. (devifirda.ml)
  • Drug information on Unasyn (ampicillin and sulbactam), includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to.Ampicillin and Sulbactam - NDC Code. (devifirda.ml)
  • Data from a controlled clinical trial conducted in pediatric patients provided evidence supporting the safety and efficacy of UNASYN for the treatment of skin and skin structure infections. (com.gt)
  • Of 99 pediatric patients evaluable for clinical efficacy, 60 patients received a regimen containing intravenous UNASYN, and 39 patients received a regimen containing intravenous cefuroxime. (com.gt)
  • The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure infection (cSSSI). (clinicaltrials.gov)
  • It is well known that the overuse of antibiotics has several important consequences such as increased treatment costs, reduced clinical efficacy, and above all, the increased emergence of antibiotic-resistant pathogens. (druglib.com)
  • Ampicillin-Sulbactam is a commonly used 'first line' antibiotic for intra-abdominal infections. (druglib.com)
  • Ampicillin/sulbactam is a combination of the common penicillin -derived antibiotic ampicillin and sulbactam , an inhibitor of bacterial beta-lactamase . (bingj.com)
  • These authors discuss the recent Infectious Diseases Society of America guideline on diabetic foot infections, emphasize the importance of a team approach in managing inpatients with diabetic foot disorders and investigate the efficacy of promising new antibiotic agents. (podiatrytoday.com)
  • In other antibiotic changes, amoxicillin (without clavulanate) and ampicillin (without sulbactam) are no longer recommended for patients with comorbidities because they do not cover β-lactamase producing Haemophilus influenzae , Moraxella catarrhalis , methicillin-susceptible S aureus (MSSA), and certain gram-negative bacilli. (contagionlive.com)
  • Review: taking Propofol and Ampicillin And Sulbactam together.Ampicillin and Sulbactam for Injection, USP is an injectable antibacterial combination consisting of the.Ampicillin-Sulbactam is an antibiotic that is FDA approved for the treatment of beta. (devifirda.ml)
  • With the efficacy of available antibiotics diminishing and the dearth of development of new antibiotics, restricting the use of effective antibiotics with relatively low resistance rates is imperative to preserve an efficacious antibiotic pipeline," the group members wrote. (healio.com)
  • The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients. (knowcancer.com)
  • Phase IV Study of Determining the Efficacy of Ampicillin/Sulbactam Combination as Antibiotic Prophylaxis During Breast Cancer Surgery in Patients With a Body Mass Index (BMI) Over 25. (knowcancer.com)
  • We are developing ETX2514SUL, a fixed-dose combination of ETX2514 with sulbactam, as a novel IV antibiotic for the treatment of infections caused by carbapenem-resistant Acinetobacter . (entasistx.com)
  • Adult outpatient therapy A 2014 Cochrane review covering 11 randomized controlled trials (RCTs) of 3352 participants older than 12 years with a diagnosis of CAP reported that, for outpatients, there was no advantage of one antibiotic over another for efficacy when the comparison was either between fluoroquinolones and macrolides or between different macrolides (1). (essentialmeds.org)
  • CONCLUSION: The clinical efficacy and tolerability of cefoperazone-sulbactam are comparable to those of comparator drugs in the treatment of febrile neutropenia. (bvsalud.org)
  • Comparison of gastrointestinal safety and tolerability of aceclofenac with diclofenac: a multicenter, randomized, double-blind study in patients with knee osteoarthritis. (ipca.com)
  • To compare the gastrointestinal (GI) tolerability and efficacy of aceclofenac with diclofenac in patients with knee osteoarthritis (OA). (ipca.com)
  • Clinical efficacy, ampicillin 250 mg dosage safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies. (swirlandsparkle.com)
  • A systematic literature review and meta-analysis was conducted to evaluate the comparative efficacy and tolerability of cefazolin versus anti-staphylococcal penicillins (ASPs) for methicillin-suscepti. (bioportfolio.com)
  • evaluate efficacy, safety and tolerability of Ampicillin/Sulbactan compared to Amoxicillin/Clavulanate in upper respiratory tract infections in adults. (pdfmedarticles.com)
  • Currently, the very few treatment options still effective against Acinetobacter infections have poor efficacy and tolerability, resulting in mortality rates approaching 50% for Acinetobacter pneumonia and bacteremia infections. (entasistx.com)
  • Ampicillin-sulbactam: 1.5 g (1 g ampicillin plus 0.5 g sulbactam) to 3 g (3 g ampicillin plus 1 g sulbactam) intravenous (IV) every 6 hrs or Amoxicillin-clavulanate: 1.2 g (1000 mg amoxicillin plus 200 mg clavulanate) IV every 6 to 8 hrs. (clinicaltrials.gov)
  • Fixed dose combination of cefepime and sulbactam (1.5 g to 3 g, intravenous [i.v.] twice daily). (isrctn.com)
  • Immediately after completion of a 15-minute intravenous infusion of ampicillin and sulbactam for injection, peak serum concentrations of ampicillin and sulbactam are attained. (nih.gov)
  • This study was to assess the safety of sequential intravenous (IV)/oral (PO) moxifloxacin (Avelox®) compared with sequential IV/PO levofloxacin (Levaquin®) in the treatment of elderly su. (bioportfolio.com)
  • This study will assess the efficacy and safety of intravenous beta-lactam, in comparison with ceftriaxone, in hospitalized patients with community-acquired pneumonia not caused by Legionel. (bioportfolio.com)
  • Ampicillin-sulbactam has been widely used in the newborn nursery as the empirical antibiotics as well as ampicillin and gentamicin. (neo-med.org)
  • And generic only in the United States, ampicillin/sulbactam is used to treat infections caused by bacteria resistant to beta-lactam antibiotics . (bingj.com)
  • As with many other antibiotics, under-dosing of ampicillin/sulbactam may lead to resistance. (bingj.com)
  • Ampicillin and sulbactam are both hydrophilic antibiotics and have a volume of distribution (Vd) similar to the volume of extra-cellular body water. (bingj.com)
  • Its spectrum of activity is enhanced by co-administration of sulbactam, a drug that inhibits beta lactamase, an enzyme produced by bacteria to inactivate ampicillin and related antibiotics. (wikipedia.org)
  • Available evidence is insufficient to draw any conclusions regarding the efficacy or side-effects related to the administration of prophylactic antibiotics to women with meconium-stained amniotic fluid. (who.int)
  • This Cochrane (10) review aimed to evaluate the efficacy and side-effects of the use of prophylactic antibiotics during labour to prevent maternal and neonatal infections associated with MSAF. (who.int)
  • Ampicillin and sulbactam are antibiotics in the penicillin group of drugs. (devifirda.ml)
  • In this meta-analysis, only randomized controlled trials comparing the treatment efficacy of novel ß-lactam/ß-lactamase inhibitor combinations with other antibiotics for cUTI/APN in adult patients were included. (bvsalud.org)
  • These combinations also share a safety profile similar to that of other antibiotics. (bvsalud.org)
  • Only clinical trials comparing cefoperazone-sulbactam with other antibiotics for empiric treatment of febrile neutropenia were included. (bvsalud.org)
  • Ceftriaxone (CTRX) and ampicillin/sulbactam (ABPC/SBT) are recommended by various guidelines as the first-line antibiotics for community-acquired pneumonia (CAP). (biomedcentral.com)
  • The expression of Class D β-lactamases, often in combination with Class A and/or Class C β-lactamases drives Acinetobacter resistance to β-lactam antibiotics like sulbactam. (entasistx.com)
  • Prior to β-lactamase-mediated resistance, sulbactam was one of the few antibiotics of choice for the treatment of Acinetobacter infections. (entasistx.com)
  • Sulbactam inhibits plasmid-medicated beta-lactamase enzymes commonly found in microorganisms resistant to ampicillin. (drugster.info)
  • Entasis is developing ETX0282 in combination with cefpodoxime, an orally available cephalosporin approved for treating a variety of bacterial infections but lacking in efficacy due to beta-lactamase mediated resistance. (entasistx.com)
  • Comparative evaluation of efficacy and safety of artesunate-lumefantrine vs. artemether-lumefantrine fixed-dose combination in the treatment of uncomplicated Plasmodium falciparum malaria. (ipca.com)
  • To establish efficacy and safety of artesunate/lumefantrine fixed-dose combination (FDC) in comparison with artemether/lumefantrine FDC in treatment of uncomplicated Plasmodium falciparum malaria. (ipca.com)
  • Ampicillin/Sulbactam and Sultamicillin in Pediatric. (cuper.tk)
  • Tripodi MF, Durante-Mangoni E, Fortunato R, Utili R, Zarrilli R (2007) Comparative activities of colistin, rifampicin, imipenem and sulbactam/ampicillin alone or in combination against epidemic multidrug-resistant Acinetobacter baumannii isolates producing OXA-58 carbapenemases. (springer.com)
  • Florescu DF, Qiu F, McCartan MA, Mindru C, Fey PD, Kalil A (2012) What is the efficacy and safety of colistin for the treatment of ventilator-associated pneumonia? (springer.com)
  • Michalopoulos AS, Falagas ME (2011) Colistin: recent data on pharmacodynamics properties and clinical efficacy in critically ill patients. (springer.com)
  • Efficacy and safety of colistin in the treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in patients with hematologic malignancy: a matched pair analysis. (springermedizin.at)
  • The purpose of this investigation was to compare the efficacy of colistin-based therapies in extremely drug-resistant Acinetobacter spp. (curehunter.com)
  • To study the efficacy of intratracheal colistin sulfate therapy in a murine model of acute pneumonia caused by a clinical CRAB strain, Ab396. (curehunter.com)
  • We reviewed the most recent literature on colistin treatment, focusing on efficacy and toxicity issues. (springeropen.com)
  • There were three cases (10%) of bacterial culture positive patients in amoxicillin-sulbactam treated group during treatment. (neo-med.org)
  • The purpose of the study is to evaluate the effectiveness and safety of Avelox in a 5 day treatment of adult patients with acute bacterial sinusitis and to measure the amount of time it ta. (bioportfolio.com)
  • Asmaa F. Abbassy ,Aly Said ,Aly Gaber , Intramuscular sulbactam/ampicillin combination therapy in gynecological and obstetrical bacterial infections, Med. (who.int)
  • bioMérieux SA English - 1 16263 B - en - 2012/07 CUSTOMER INFORMATION SHEET Antimicrobial agents with bactericidal and bacteriostatic modes of action.Online Pharmacy, fetal warfarin syndrome mnemonic, is penicillin in cefdinir, ibuprofen bulk price india - DrugsUpdate India.Un mot de passe vous sera envoyé par email. (gov10.gq)
  • The safety of a penicillin in a cephalosporin-allergic patient depends on whether the patient is truly allergic, when the reaction occurred, and. (gov10.gq)
  • This was the largest U.S. demonstration of a rapid, global production the penicillin penicillin-sulbactam cocktail for treating multiple sclerosis. (carbonflo.com)
  • An alternative strategy to that of the penicillin-sulbactam cocktail is to give an entire cocktail, the report said. (carbonflo.com)
  • With this cocktail, a tablet of penicillin is added to a cocktail of daptomycin and penicillin-sulbactam, then a placebo tablet is added when the person given a treatment. (carbonflo.com)
  • In addition, the combination of daptomycin and penicillin-sulbactam is also very effective to treat inflammatory bowel diseases and psoriasis, he said. (carbonflo.com)
  • In 2011, when he completed a postdoctoral fellowship at University Tadacip 20 medicine College London, Peter Allen, professor and director of the MRC Microbiology Institute, was recruited to study and apply the combination of penicillin and penicillin-sulbactam for resistance to Sabin-1. (carbonflo.com)
  • Efficacy was observed in three patients (PISP two, PRSP one) with penicillin-resistant S. pneumoniae . (dosingpdf.com)
  • With regard to sensitivity of penicillin-G , MIC ≦2 μg , MIC =4μg , and MIC ≧8μg were judged Bacteriological efficacy (Table 4) PSSP 19 strains, PISP two strains, and PRSP one DISCUSSION strain were isolated, and all were eradicated. (dosingpdf.com)
  • Co-amoxiclav (Amoxicillin/clavulanic acid) 1 · Imipenem/cilastatin 1 · Ampicillin/sulbactam.Ampicillin 500 Mg Dosage. (nudecam.ml)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of ampicillin and sulbactam for injection and other antibacterial drugs, ampicillin and sulbactam for injection should be used only to treat infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • After an intramuscular injection of 1000 mg ampicillin plus 500 mg sulbactam, peak ampicillin serum levels ranging from 8 to 37 mcg/mL and peak sulbactam serum levels ranging from 6 to 24 mcg/mL are attained. (nih.gov)
  • Approximately 75 to 85% of both ampicillin and sulbactam are excreted unchanged in the urine during the first 8 hours after administration of ampicillin and sulbactam for injection to individuals with normal renal function. (nih.gov)
  • The dose of ampicillin and sulbactam for injection in such patients should be administered less frequently in accordance with the usual practice for ampicillin (see DOSAGE AND ADMINISTRATION section). (nih.gov)
  • Penetration of both ampicillin and sulbactam into cerebrospinal fluid in the presence of inflamed meninges has been demonstrated after IV administration of ampicillin and sulbactam for injection. (nih.gov)
  • Ampicillin and sulbactam for injection may be administered by deep intramuscular injection. (devifirda.ml)
  • While ampicillin and sulbactam for injection is indicated only for. (devifirda.ml)
  • GMT Pharma International - Offering Veterinary Ceftriaxone And Sulbactam For Injection, Packaging Type: Glass Ampoules at Rs 6500/number in Sirmaur, Himachal Pradesh. (boplight-team.pl)
  • The objective of this study was to compare efficacy and safety Cefotaxime/ Sulbactam (CTS) and Piperacillin/ Tazobactam (PT) combinations in complicated Urinary Tract Infections. (ijbcp.com)
  • Efficacy for this organism in this organ system was studied in fewer than 10 infections. (rxlist.com)
  • Ampicillin/sulbactam is also used when the cause of an infection is not known ( empiric therapy ), such as intra-abdominal infections , skin infections, pneumonia , and gynecologic infections . (bingj.com)
  • Using typical doses, ampicillin/sulbactam has been shown to reach desired levels to treat infections in the brain, lungs, and abdominal tissues. (bingj.com)
  • Efficacy and safety of daptomycin in the treatment of Gram-positive catheter-related bloodstream infections in cancer patients. (springer.com)
  • Clinical and bacteriological assessment of efficacy of intramuscular sulbactam / ampicillin combination, together with assessment of its toleration and safety in the treatment of gynecological and obstetrical infections were carried out thirty adult females with pelvic inflammatory disease, wound infections, vaginitis and puerperal sepsis received intramuscular sulbactam / ampicillin combination in a total daily dose of 1. (who.int)
  • This 3 arm study will compare the efficacy and safety of beta-lactam with that of 'standard care' in patients with complicated skin and skin structure infections requiring hospitalization. (bioportfolio.com)
  • Sulbactam (SUL) is a generic β-lactam antimicrobial with activity against Acinetobacter baumannii infections, but β-lactamase-mediated resistance to sulbactam is now widespread rendering it generally ineffective. (entasistx.com)
  • The purpose of this study was to evaluate the effect of obesity on ceftriaxone efficacy when used as definitive monotherapy to treat infections. (boplight-team.pl)
  • Ampicillin/sulbactam in elderlypatients with community-acquired pneumonia. (diako-online.de)
  • Piperacillin/tazobactam vs. cefoperazone/sulbactam in adult low-risk febrile neutropenia cases. (springer.com)
  • Peak ampicillin serum levels ranging from 109 to 150 mcg/mL are attained after administration of 2000 mg of ampicillin plus 1000 mg sulbactam and 40 to 71 mcg/mL after administration of 1000 mg ampicillin plus 500 mg sulbactam. (nih.gov)
  • After a 2000 mg ampicillin dose with 1000 mg sulbactam, video roulette game peak ampicillin serum levels ranging from 109 to 150 mcg/mL and peak sulbactam concentrations ranging from 48 to 88 mcg/mL are attained. (showwhoyouareportraits.com)
  • Cefoperazone-sulbactam plus amikacin emp. (cu.edu.tr)
  • Aim: To determine the efficacy and safety of cefoperazone-sulbactam combined with amikacin in the treatment of febrile neutropenia in children with cancer. (cu.edu.tr)
  • PURPOSE: This meta-analysis assessed the clinical efficacy and safety of cefoperazone-sulbactam for empiric therapy febrile neutropenia. (bvsalud.org)
  • The patient was treated with a combination of cefoperazone sulbactam, linezolid and voriconazole for 10 days, and the symptoms improved. (bvsalud.org)
  • Likewise, to concern the degradation products, a combination of cefoperazone with sulbactam should not be mixed with PD solutions. (hsri.or.th)
  • Some side effects of ampicillin / sulbactam may occur that usually do not need medical attention. (drugs.com)
  • The addition of sulbactam to ampicillin enhances the effects of ampicillin. (bingj.com)
  • May impair bactericidal effects of ampicillin/sulbactam. (drugster.info)
  • Another three - ampicillin/sulbactam, levofloxacin and moxifloxacin - were rejected by a majority. (healio.com)
  • 500 mg order ampicillin dosage purchase ampicillin online where to buy ampicillin for fish buy ampicillin sulbactam order ampicillin and pregnancy. (nudecam.ml)
  • Bring our free Ampicillin And Sulbactam coupon card to the pharmacy to receive the lowest price possible on your medication.Includes: indications, dosage, adverse reactions, pharmacology and more. (devifirda.ml)
  • Efficacy and safety of ampicillin/sulbactam and cefuroxime in the treatment of. (nudecam.ml)
  • Genetics is a prominent form of cephalosporin or 4-6 there is a members of the same as an active ingredient not exhibit acne.Ampicillin/Sulbactam versus Cefuroxime as antimicrobial prophylaxis for cesarean delivery: a randomized study. (gov10.gq)
  • A prospective, multi centre, randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin-Sulbactam 3 days in the treatment of localized community acquired intra-abdominal infection. (druglib.com)
  • T.E.A. Study: Three days Ertapenem vs three days Ampicillin-sulbactam). (druglib.com)
  • Ertapenem and Ampicillin-sulbactam are recommended as primary treatment agents for localized peritonitis by both the SIS and IDSA guidelines. (druglib.com)
  • Phase IV Open-Label Foot Infection Study is being conducted to generate comparative Efficacy and Safety data in Diabetic Inpatients. (clinicaltrials.gov)
  • Objective: To evaluate the efficacy and safety of ampicillin sulbactam (3 g every 6 hours) in patients with pelvic inflammatory disease or postpartum endometritis using a randomized, comparative, multicenter study of parallel design. (elsevier.com)
  • OBJECTIVES: This meta-analysis assessed the efficacy and safety of novel ß-lactam/ß-lactamase inhibitor combinations in the treatment of complicated urinary tract infection (cUTI)/acute pyelonephritis (APN). (bvsalud.org)
  • CE population were those who completed TOC assessment of cure or failure (but not indeterminate) or, in case of premature discontinuation due to lack of efficacy, had completed end of treatment assessment such that assessment of clinical response could be made. (clinicaltrials.gov)
  • Sulbactam 3 days in the treatment of localized community acquired intra-abdominal infection. (biomedcentral.com)
  • The purpose of this trial is to determine the efficacy and safety of Moxifloxacin in comparison to Sulbactam/Ampicillin in the treatment of pulmonary abscesses and aspiration pneumonia. (bioportfolio.com)
  • Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder. (frugalshopper.ca)
  • X Ampicillin-sulbactam (750 mg) given orally twice daily for 10 days was evaluated for the treatment of acute pelvic inflammatory disease (PID).Ampicillin + Sulbactam AMS 20 (10+10). (nudecam.ml)
  • These findings suggest that although not better, daptomycin efficacy is comparable to vancomycin if used as empiric therapy in the treatment of adult febrile neutropenia. (springer.com)
  • Conclusion: Ampicillin-sulbactam is as effective and well tolerated as combination regimens using cefoxitin plus doxycycline and clindamycin plus gentamicin for the treatment of pelvic inflammatory disease or endometritis, respectively. (elsevier.com)
  • The mortality rate during treatment was 17.9 % in sulbactam group, and 25.0 % in tigecycline group ( P = 0.259). (springer.com)
  • Before that, sulbactam or ampicillin/sulbactam might be the only treatment option with in vitro activity against MDR Acb complex. (springer.com)
  • Thus, we conducted a retrospective study to compare the efficacy of tigecycline-based with sulbactam (or ampicillin/sulbactam)-based treatment for pneumonia involving MDR Acb complex. (springer.com)
  • Objective: The safety and efficacy of ampicillin plus sulbactam were compared with those of cefoxitin in the treatment of women with pelvic inflammatory. (devifirda.ml)
  • Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial? (billwedekind.com)
  • These results together with its generally tolerable safety profile and the added advantage of oral administration provide the basis for further evaluating capecitabine as a single agent or in combination with other treatment modalities in this patient population. (pianolarge.cf)
  • Phototherapy is a mainstay of vitiligo treatment and has varying rates of efficacy. (biomedsearch.com)
  • BACKGROUND AND OBJECTIVES: To evaluate the safety and efficacy of a home-use hair removal diode laser (TRIA Beauty, Inc., Dublin, CA) in a multiple treatment regimen. (biomedsearch.com)
  • sulbactam may be used to treat certain sexually transmitted diseases (STD), encorate syrup 200ml price the drug may mask or delay the symptoms of incubating syphilis when given as part of an STD treatment regimen! (smyrnachiropractic.com)
  • We believe that ETX2514's expanded coverage against Classes A, C and D β-lactamases gives it the potential to restore the efficacy of sulbactam against multidrug- and carbapenem-resistant Acinetobacter , once again providing physicians with a safe and effective treatment option for their patients. (entasistx.com)
  • No specific antimicrobial in terms of route, dose, schedules, and optimal antimicrobial agent or regimen appear to have superior efficacy for treatment of PD-related peritonitis. (hsri.or.th)
  • Aampicillin-sulbactam and vancomycin. (nudecam.ml)
  • The purpose of this study was to compare the efficacy and safety of amoxicillin-sulbactam to ampicillin-sulbactam in treating neonatal sepsis. (neo-med.org)
  • To compare the efficacy of tigecycline-based with sulbactam (or ampicillin/sulbactam)-based therapy for pneumonia involving MDR Acb complex, we conducted a retrospective study comparing 84 tigecycline-treated adult patients during the period August 2007 to March 2010 with 84 sulbactam or ampicillin/sulbactam-treated adult patients during the period September 2004 to July 2007. (springer.com)
  • Patients treated with either tigecycline-based or sulbactam-based therapy had a similar clinical outcome, but tigecycline group had a lower microbiological eradiation rate. (springer.com)
  • With a match in the Acute Physiology and Chronic Health Evaluation (APACHE) II score for both groups, a comparison was made between tigecycline-treated adult patients during the period August 2007 to March 2010 and sulbactam (or ampicillin/sulbactam)-treated adult patients during the period September 2004 to July 2007. (springer.com)
  • These microFIA systems have been applied to clinical analysis, assessment of food safety, in vivo and real-time determination of drugs, and pharmacokinetics studies. (pianolarge.cf)
  • Ko WC, Lee HC, Chiang SR et al (2004) In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain. (springer.com)
  • Efficacy and Safety of Amoxicillin-sulbactam and Ampicillin-sulbactam in Full Term Neonates. (neo-med.org)
  • The patients were randomly assigned to receive amoxicillin-sulbactam 30 mg/kg/day (based on amoxicillin component) intravenously divided every 12 hours or ampicillin-sulbactam 75 mg/kg/day (based on ampicillin component) intravenously divided every 8 hours for at least 7 consecutive days. (neo-med.org)
  • CONCLUSION: Amoxicillin-sulbactam was as effective and safe as ampicillin-sulbactam for whom neonatal sepsis was suspected. (neo-med.org)
  • Ampicillin/sulbactam has poor absorption when given orally. (bingj.com)
  • All patients were evaluated for clinical efficacy on the basis of the clinical, microbiological responses and side effects. (neo-med.org)
  • In patients with impaired renal function the elimination kinetics of ampicillin and sulbactam are similarly affected, hence the ratio of one to the other will remain constant whatever the renal function. (nih.gov)
  • It is intended to be a step in broader evaluation of safety and efficacy of drug prescription in neonatal sepsis patients. (scopemed.org)
  • Patients received 150 to 300 mg/kg/day ampicillin/sulbactam in equally divided. (nudecam.ml)
  • Methods: Eligible patients with pelvic inflammatory disease were randomized to receive either ampicillin-sulbactam or cefoxitin (2 g every 6 hours) plus doxycycline (100 mg every 12 hours). (elsevier.com)
  • In the ampicillin-sulbactam group, chlamydia-positive patients also received oral doxycycline. (elsevier.com)
  • The percentages of patients with pelvic inflammatory disease who had adverse experiences were not significantly different in the cefoxitin and doxycycline group (47% [29 of 62]) than in those receiving ampicillin-sulbactam (33% [22 of 66]) (P=.12). (elsevier.com)
  • Yet, no prospective randomized study assessed the efficacy of chemoprophylaxis during breast surgery in overweight patients. (knowcancer.com)
  • Clinical efficacy, bacteriological efficacy, and side effects of these patients were prospectively examined. (dosingpdf.com)
  • Therefore, the pediatric dosages provided in these guidelines are based largely on pharmacokinetic data and the extrapolation of adult efficacy data to pediatric patients. (basicmedicalkey.com)
  • Safety and efficacy in patients below the age of 18 years has not been established. (ciolofoods.com)
  • However, when ampicillin is given in combination with sulbactam, regrowth of bacteria has been seen when sulbactam levels fall below certain concentrations. (bingj.com)
  • Use of ticarcillin/clavulanate was eventually discontinued because of safety concerns. (healio.com)
  • The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. (clinicaltrials.gov)
  • The concentration of sulbactam used in this study was 8 mg/L, corresponding to the standard dose used for carrying out. (nudecam.ml)
  • Since then, additional studies with different cocktail configurations have been conducted, including a clinical study to assess the safety and efficacy of using the newer combination daptomycin (a preeminent monoclonal antibody to Sabin-1) in multiple sclerosis. (carbonflo.com)
  • In addition, the study to compare effectiveness, safety, and cost-utility of chlorhexidine gluconate (CHG)-soaked cloths to mupirocin ointment and exit site usual care (normal saline) with aseptic technique in prevention of PD-related infection is ongoing to the second year. (hsri.or.th)
  • IV 300 mg/kg/day (200 mg ampicillin/100 mg sulbactam) in divided doses every 6 h. (drugster.info)
  • Results: For pelvic inflammatory disease, the clinical response rates (cure or improvement) were 85.5% (47 of 55) and 89.6% (43 of 48) in the ampicillin-sulbactam and cefoxitin and doxycycline groups, respectively (χ 2 =0.10, P=.76). (elsevier.com)
  • Those with endometritis were randomized to ampicillin-sulbactam or clindamycin (900 mg every 8 hours) plus gentamicin (1.5 mg/kg every 8 hours). (elsevier.com)
  • For endometritis, the clinical response rates were 88.7% (141 of 159) and 90.8% (139 of 153) in the ampicillin sulbactam and clindamycin and gentamicin groups, respectively (χ 2 =0.15, P=.70). (elsevier.com)
  • Escherichia coli resistance to ampicillin/sulbactam has been observed in numerous studies," the authors wrote. (healio.com)
  • Ampicillin And Sulbactam with NDC 66794-207 is a a human prescription drug product labeled by Piramal Critical Care Inc. The generic name of Ampicillin And Sulbactam is ampicillin and sulbactam. (ndclist.com)
  • Sulbactam blocks the enzyme which breaks down ampicillin and thereby allows ampicillin to attack and kill the bacteria. (bingj.com)
  • Diagnosis (Dx) ICD-10-CM - 2016 Code Set DRG - Diagnosis.NDC 55150-0117-20 is a form of Ampicillin And Sulbactam packaged by AuroMedics Pharma LLC.AIDSinfo provides the following drug label solely as an example of the. (devifirda.ml)
  • Improving methods for analysing anti-malarial drug efficacy trials: molecular correction based on length-polymorphic markers msp-1 , msp-2 and glurp . (asm.org)
  • 19,22,23,31,32 There are sufficient pharmacokinetic studies of most agents to recommend pediatric dosages that provide adequate systemic exposure and, presumably, efficacy comparable to that demonstrated in adults. (basicmedicalkey.com)