Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.Food Additives: Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Databases, Chemical: Databases devoted to knowledge about specific chemicals.Cations: Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.Databases, Pharmaceutical: Databases devoted to knowledge about PHARMACEUTICAL PRODUCTS.Pharmacological Processes: The metabolism of drugs and their mechanisms of action.Lanthanum: Lanthanum. The prototypical element in the rare earth family of metals. It has the atomic symbol La, atomic number 57, and atomic weight 138.91. Lanthanide ion is used in experimental biology as a calcium antagonist; lanthanum oxide improves the optical properties of glass.Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.PolyaminesChlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.Anti-Infective Agents, Local: Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.Mouthwashes: Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)Antisepsis: The destruction of germs causing disease.Sodium Hypochlorite: It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant & Hackh's Chemical Dictionary, 5th ed)Disinfectants: Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)GluconatesCalcium Gluconate: The calcium salt of gluconic acid. The compound has a variety of uses, including its use as a calcium replenisher in hypocalcemic states.1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt: A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From Merck Index, 11th ed)EthylenediaminesChina: A country spanning from central Asia to the Pacific Ocean.Chelating Agents: Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.Biotechnology: Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.Diamines: Organic chemicals which have two amino groups in an aliphatic chain.Heterocyclic Compounds, 1-Ring: A class of organic compounds containing a ring structure made up of more than one kind of atom, usually carbon plus another atom. The ring structure can be aromatic or nonaromatic.Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.Outsourced Services: Organizational activities previously performed internally that are provided by external agents.Salts: Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Magnesium: A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.Hydrogen: The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.Muramidase: A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17.Sodium: A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.Sodium Channels: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.Sodium, Dietary: Sodium or sodium compounds used in foods or as a food. The most frequently used compounds are sodium chloride or sodium glutamate.Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Developing Countries: Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.Sodium Channel Blockers: A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.Sodium Isotopes: Stable sodium atoms that have the same atomic number as the element sodium, but differ in atomic weight. Na-23 is a stable sodium isotope.Sodium Dodecyl Sulfate: An anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.Accreditation: Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.Employee Discipline: Regulations or conditions imposed on employees by management in order to correct or prevent behaviors which are counterproductive to the organization.Oenothera: A plant genus of the family ONAGRACEAE. Members contain oenotheins.Death Certificates: Official records of individual deaths including the cause of death certified by a physician, and any other required identifying information.Professional Misconduct: Violation of laws, regulations, or professional standards.Joint Commission on Accreditation of Healthcare Organizations: A private, voluntary, not-for-profit organization which establishes standards for the operation of health facilities and services, conducts surveys, and awards accreditation.Birth Certificates: Official certifications by a physician recording the individual's birth date, place of birth, parentage and other required identifying data which are filed with the local registrar of vital statistics.Viola: A plant genus of the family VIOLACEAE. Some species in this genus are called bouncing bet which is a common name more often used with SAPONARIA OFFICINALIS. Members contain macrocyclic peptides.Ontario: A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)Medical Staff, Hospital: Professional medical personnel approved to provide care to patients in a hospital.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Toll-Like Receptor 4: A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.Toll-Like Receptors: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Toll-Like Receptor 9: A pattern recognition receptor that binds unmethylated CPG CLUSTERS. It mediates cellular responses to bacterial pathogens by distinguishing between self and bacterial DNA.Toll-Like Receptor 6: A pattern recognition receptor that forms heterodimers with TLR2 RECEPTOR. The complex interacts with a variety of ligands including LIPOPROTEINS from MYCOPLASMA.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Myeloid Differentiation Factor 88: An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Egypt: A country in northern Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip, and the Red Sea north of Sudan, and includes the Asian Sinai Peninsula Its capital is Cairo.Headache Disorders, Secondary: Conditions with HEADACHE symptom that can be attributed to a variety of causes including BRAIN VASCULAR DISORDERS; WOUNDS AND INJURIES; INFECTION; drug use or its withdrawal.Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.International Cooperation: The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.International Agencies: International organizations which provide health-related or other cooperative services.Stars, Celestial: Large bodies consisting of self-luminous gas held together by their own gravity. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)Drug Packaging: Containers, packaging, and packaging materials for drugs and BIOLOGICAL PRODUCTS. These include those in ampule, capsule, tablet, solution or other forms. Packaging includes immediate-containers, secondary-containers, and cartons. In the United States, such packaging is controlled under the Federal Food, Drug, and Cosmetic Act which also stipulates requirements for tamper-resistance and child-resistance. Similar laws govern use elsewhere. (From Code of Federal Regulations, 21 CFR 1 Section 210, 1993) DRUG LABELING is also available.Humidity: A measure of the amount of WATER VAPOR in the air.Aedes: A genus of mosquitoes (CULICIDAE) frequently found in tropical and subtropical regions. YELLOW FEVER and DENGUE are two of the diseases that can be transmitted by species of this genus.Nisin: A 34-amino acid polypeptide antibiotic produced by Streptococcus lactis. It has been used as a food preservative in canned fruits and vegetables, and cheese.Struthioniformes: An order of flightless birds comprising the ostriches, which naturally inhabit open, low rainfall areas of Africa.Food Preservatives: Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.Rheiformes: An order of large, long-necked, long-legged, flightless birds, found in South America. Known as rheas, they are sometimes called American ostriches, though they are in a separate order from true OSTRICHES.

Modulation of distal colonic epithelial barrier function by dietary fibre in normal rats. (1/4006)

BACKGROUND: Dietary fibre influences the turnover and differentiation of the colonic epithelium, but its effects on barrier function are unknown. AIMS: To determine whether altering the type and amount of fibre in the diet affects paracellular permeability of intestinal epithelium, and to identify the mechanisms of action. METHODS: Rats were fed isoenergetic low fibre diets with or without supplements of wheat bran (10%) or methylcellulose (10%), for four weeks. Paracellular permeability was determined by measurement of conductance and 51Cr-EDTA flux across tissue mounted in Ussing chambers. Faecal short chain fatty acid (SCFA) concentrations were assessed by gas chromatography, epithelial kinetics stathmokinetically, and mucosal brush border hydrolase activities spectrophotometrically. RESULTS: Body weight was similar across the dietary groups. Conductance and 51Cr-EDTA flux were approximately 25% higher in animals fed no fibre, compared with those fed wheat bran or methylcellulose in the distal colon, but not in the caecum or jejunum. Histologically, there was no evidence of epithelial injury or erosion associated with any diet. The fibres exerted different spectra of effects on luminal SCFA concentrations and pH, and on mucosal indexes, but both bulked the faeces, were trophic to the epithelium, and stimulated expression of a marker of epithelial differentiation. CONCLUSIONS: Both a fermentable and a non-fermentable fibre reduce paracellular permeability specifically in the distal colon, possibly by promoting epithelial cell differentiation. The mechanisms by which the two fibres exert their effects are likely to be different.  (+info)

Intracellular EDTA mimics parvalbumin in the promotion of skeletal muscle relaxation. (2/4006)

Parvalbumin (PA) is an intracellular Ca2+-binding protein found in some muscle and nerves. Its ability to bind Ca2+ and facilitate skeletal muscle relaxation is limited by its Mg2+ off-rate. EDTA serves as an "artificial" PA in that it exhibited similar rate constants for Mg2+ (3 s-1) and Ca2+ (0.7 s-1) dissociation at 10 degrees C. When introduced into frog skeletal muscle, EDTA increased the relaxation rate by approximately 2.7-fold, and with increasing tetanus duration, EDTA lost its ability to contribute to relaxation (and Ca2+ sequestration) at its Mg2+ off-rate. Intracellular EDTA recovered its ability to contribute to muscle relaxation and Ca2+ sequestration at its Ca2+ off-rate. Like PA, EDTA's contribution to muscle relaxation and Ca2+ sequestration was more clearly observed when the SR Ca-ATPase was inhibited. Introduction of EDTA into rat soleus muscle, which has low [PA], increased the relaxation rate in a manner that was analogous to the way in which PA facilitates relaxation of frog skeletal muscle. Thus intracellular EDTA serves as an effective mimic of PA, and its use should aid in our understanding of PA's function in muscle and nerve.  (+info)

Engineering a chimeric pyrroloquinoline quinone glucose dehydrogenase: improvement of EDTA tolerance, thermal stability and substrate specificity. (3/4006)

An engineered Escherichia coli PQQ glucose dehydrogenase (PQQGDH) with improved enzymatic characteristics was constructed by substituting and combining the gene-encoding protein regions responsible for EDTA tolerance, thermal stability and substrate specificity. The protein region responsible for complete EDTA tolerance in Acinetobacter calcoaceticus, which is recognized as the indicator of high stability in co-factor binding, was elucidated. The region is located between 32 and 59% from the N-terminus of A. calcoaceticus PQQGDH(A27 region) and also corresponds to the same position from 32 to 59% from the N-terminus in E. coli PQQGDH, though E. coli PQQGDH is EDTA sensitive. We previously reported that the C-terminal 3% region of A. calcoaceticus (A3 region) played an important role in the increase of thermal stability, and that His775Asn substitution in E. coli PQQGDH resulted in an increase in the substrate specificity of E. coli PQQGDH towards glucose. Based on these findings, chimeric and/or mutated PQQGDHs, E97A3 H775N, E32A27E41 H782N, E32A27E38A3 and E32A27E38A3 H782N were constructed to investigate the compatibility of two protein regions and one amino acid substitution. His775 substitution to Asn corresponded to His782 substitution to Asn (H782N) in chimeric enzymes harbouring the A27 region. Since all the chimeric PQQGDHs harbouring the A27 region were EDTA tolerant, the A27 region was found to be compatible with the other region and substituted amino acid responsible for the improvement of enzymatic properties. The contribution of the A3 region to thermal stability complemented the decrease in the thermal stability due to the His775 or His782 substitution to Asn. E32A27E38A3 H782N, which harbours all the above mentioned three regions, showed improved EDTA tolerance, thermal stability and substrate specificity. These results suggested a strategy for the construction of a semi-artificial enzyme by substituting and combining the gene-encoding protein regions responsible for the improvement of enzyme characteristics. The characteristics of constructed chimeric PQQGDH are discussed based on the predicted model, beta-propeller structure.  (+info)

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG). (4/4006)

Tumour-selective acidification is of potential interest for enhanced therapeutic gain of pH sensitive drugs. In this study, we investigated the feasibility of a tumour-selective reduction of the extracellular and intracellular pH and their effect on the tumour response of selected anti-cancer drugs. In an in vitro L1210 leukaemic cell model, we confirmed enhanced cytotoxicity of chlorambucil at low extracellular pH conditions. In contrast, the alkylating drugs melphalan and cisplatin, and bioreductive agents mitomycin C and its derivative EO9, required low intracellular pH conditions for enhanced activation. Furthermore, a strong and pH-independent synergism was observed between the pH-equilibrating drug nigericin and melphalan, of which the mechanism is unclear. In radiation-induced fibrosarcoma (RIF-1) tumour-bearing mice, the extracellular pH was reduced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) or its analogue benzylguanidine (BG) plus glucose. To simultaneously reduce the intracellular pH, MIBG plus glucose were combined with the ionophore nigericin or the Na+/H+ exchanger inhibitor amiloride and the Na+-dependent HCO3-/Cl- exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulphonic acid (DIDS). Biochemical studies confirmed an effective reduction of the extracellular pH to approximately 6.2, and anti-tumour responses to the interventions indicated a simultaneous reduction of the intracellular pH below 6.6 for at least 3 h. Combined reduction of extra- and intracellular tumour pH with melphalan increased the tumour regrowth time to 200% of the pretreatment volume from 5.7 +/- 0.6 days for melphalan alone to 8.1 +/- 0.7 days with pH manipulation (P < 0.05). Mitomycin C related tumour growth delay was enhanced by the combined interventions from 3.8 +/- 0.5 to 5.2 +/- 0.5 days (P < 0.05), but only in tumours of relatively large sizes. The interventions were non-toxic alone or in combination with the anti-cancer drugs and did not affect melphalan biodistribution. In conclusion, we have developed non-toxic interventions for sustained and selective reduction of extra- and intracellular tumour pH which potentiated the tumour responses to selected anti-cancer drugs.  (+info)

Effects of an angiotensin-converting enzyme inhibitor and a beta-blocker on cerebral arterioles in rats. (5/4006)

We examined the effects of an angiotensin-converting enzyme inhibitor, perindopril, and a beta-blocker, propranolol, on cerebral arterioles in stroke-prone spontaneously hypertensive rats (SHRSP). The structure and mechanics of cerebral arterioles were examined in untreated Wistar-Kyoto rats (WKY) and SHRSP that were untreated or treated for 3 months with a high (2 mg/kg per day) or a low (0.3 mg/kg per day) dose of perindopril or propranolol (250 mg/kg per day) alone or in combination with the low dose of perindopril. We measured pressure, external diameter, and cross-sectional area of the vessel wall (CSA) in maximally dilated (with EDTA) cerebral arterioles. Treatment of SHRSP with the high dose of perindopril or the combination of propranolol and the low dose of perindopril normalized cerebral arteriolar mean pressure (50+/-1 [mean+/-SEM] and 43+/-2 mm Hg vs 50+/-1 mm Hg in WKY and 94+/-3 mm Hg in untreated SHRSP; P<0.05), pulse pressure (15+/-1 and 16+/-1 mm Hg vs 13+/-1 mm Hg in WKY and 35+/-1 mm Hg in untreated SHRSP; P<0.05), and CSA (1103+/-53 and 1099+/-51 microm2, respectively, vs 1057+/-49 microm2 in WKY and 1281+/-62 microm2 in untreated SHRSP; P<0.05). In contrast, treatment of SHRSP with the low dose of perindopril or propranolol alone did not normalize arteriolar pulse pressure (24+/-1 and 21+/-1 mm Hg) and failed to prevent increases in CSA (1282+/-77 and 1267+/-94 microm2). Treatment with either dose of perindopril or the combination of propranolol and perindopril significantly increased external diameter in cerebral arterioles of SHRSP (99+/-3, 103+/-2, and 98+/-3 microm vs 87+/-2 microm in untreated SHRSP; P<0.05), whereas propranolol alone did not (94+/-3 microm; P>0.05). These findings suggest that effects of angiotensin-converting enzyme inhibitors on cerebral arteriolar hypertrophy in SHRSP may depend primarily on their effects on arterial pressure, particularly pulse pressure, whereas their effects on cerebral arteriolar remodeling (defined as a reduction in external diameter) may be pressure independent.  (+info)

Pretargeting of bacterial endocarditis in rats with streptavidin and 111In-labeled biotin. (6/4006)

A radioimaging approach for the detection of endocarditis has been investigated using two-step pretargeting with streptavidin and radiolabeled biotin. METHODS: Hemodynamic alterations within the rat heart were induced by placing an in-dwelling catheter into the left ventricle through the aortic valves. The animals were subsequently infected with Staphylococcus aureus through a tail vein. After an incubation period, rats were first injected with streptavidin and, 2 h later, with 111In-labeled ethylene-diaminetetraacetic acid-biotin. Whole-body gamma camera images were taken 4-5 h postinjection of the radiolabeled biotin. Control animals consisted of catheterized but uninfected, infected but uncatheterized and normal untreated rats. As a further control, the labeled biotin was administered to a study animal without the preadministration of streptavidin. RESULTS: Histology showed typical endocarditic changes in the hearts of study animals with massive deposition of gram-positive cocci. Catheterized but uninfected animals showed alterations corresponding to nonbacterial thrombotic endocarditis. Macroautoradiography showed accumulation of radiolabel in the endocarditic vegetations of study animals. Whole-body gamma camera images showed important cardiac uptake in 7 of 8 catheterized and infected animals and in 3 of 6 catheterized but uninfected animals. Normal rats and those infected but not catheterized showed negative results by histology, autoradiography and imaging. The percent uptake of the injected dose in the heart was 0.20 (SD = 0.13) in catheterized and infected animals, 0.12 (SD = 0.10) in catheterized but uninfected animals, 0.10 (SD = 0.04) in infected but uncatheterized animals and 0.04 (SD = 0.01) in normal control animals. CONCLUSION: The two-step pretargeting approach using streptavidin and 111In-labeled biotin was used successfully to detect S. aureus-induced bacterial endocarditis in rats.  (+info)

Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-alpha-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression. (7/4006)

The neutrophil-specific G-protein-coupled chemokine receptors, CXCR1 and CXCR2, bind with high affinity to the potent chemoattractant interleukin-8 (IL-8). The mechanisms of IL-8 receptor regulation are not well defined, although previous studies have suggested a process of ligand-promoted internalization as a putative regulatory pathway. Herein, we provide evidence for two distinct processes of CXCR1 and CXCR2 regulation. Confocal microscopy data showed a redistribution of CXCR1 expression from the cell surface of neutrophils to internal compartments after stimulation with IL-8, whereas stimulation with bacterial lipopolysaccharide (LPS) or tumor necrosis factor-alpha (TNF-alpha) did not induce CXCR1 internalization but instead mediated a significant loss of membrane-proximal CXCR1 staining intensity. To investigate whether proteolytic cleavage was the mechanism responsible for LPS- and TNF-alpha-induced downmodulation of IL-8 receptors, we tested a panel of proteinase inhibitors. The downmodulation of CXCR1 and CXCR2 by LPS and TNF-alpha was most dramatically inhibited by metalloproteinase inhibitors; 1, 10-phenanthroline and EDTA significantly attenuated LPS- and TNF-alpha-induced loss of CXCR1 and CXCR2 cell surface expression. Metalloproteinase inhibitors also blocked the release of CXCR1 cleavage fragments into the cell supernatants of LPS- and TNF-alpha-stimulated neutrophils. In addition, while treatment of neutrophils with LPS and TNF-alpha inhibited IL-8 receptor-mediated calcium mobilization and IL-8-directed neutrophil chemotaxis, both 1, 10-phenanthroline and EDTA blocked these inhibitory processes. In contrast, metalloproteinase inhibitors did not affect IL-8-mediated downmodulation of CXCR1 and CXCR2 cell surface expression or receptor signaling. Thus, these findings may provide further insight into the mechanisms of leukocyte regulation during immunologic and inflammatory responses.  (+info)

Nucleoside diphosphate kinase activity in soluble transducin preparations biochemical properties and possible role of transducin-beta as phosphorylated enzyme intermediate. (8/4006)

Known nucleoside diphosphate kinases (NDPKs) are oligomers of 17-23-kDa subunits and catalyze the reaction N1TP + N2DP --> N1DP + N2TP via formation of a histidine-phosphorylated enzyme intermediate. NDPKs are involved in the activation of heterotrimeric GTP-binding proteins (G-proteins) by catalyzing the formation of GTP from GDP, but the properties of G-protein-associated NDPKs are still incompletely known. The aim of our present study was to characterize NDPK in soluble preparations of the retinal G-protein transducin. The NDPK is operationally referred to as transducin-NDPK. Like known NDPKs, transducin-NDPK utilizes NTPs and phosphorothioate analogs of NTPs as substrates. GDP was a more effective phosphoryl group acceptor at transducin-NDPK than ADP and CDP, and guanosine 5'-[gamma-thio]triphosphate (GTP[S]) was a more effective thiophosphoryl group donor than adenosine 5'-[gamma-thio]triphosphate (ATP[S]). In contrast with their action on known NDPKs, mastoparan and mastoparan 7 had no stimulatory effect on transducin-NDPK. Guanosine 5'-[beta, gamma-imido]triphosphate (p[NH]ppG) potentiated [3H]GTP[S] formation from [3H]GDP and ATP[S] but not [3H]GTP[S] formation from [3H]GDP and GTP[S]. Depending on the thiophosphoryl group acceptor and donor, [3H]NTP[S] formation was differentially regulated by Mg2+, Mn2+, Co2+, Ca2+ and Zn2+. [gamma-32P]ATP and [gamma-32P]GTP [32P]phosphorylated, and [35S]ATP[S] [35S]thiophosphorylated, a 36-kDa protein comigrating with transducin-beta. p[NH]ppG potentiated [35S]thiophosphorylation of the 36-kDa protein. 32P-labeling of the 36-kDa protein showed characteristics of histidine phosphorylation. There was no evidence for (thio)phosphorylation of 17-23-kDa proteins. Our data show the following: (a) soluble transducin preparations contain a GDP-prefering and guanine nucleotide-regulated NDPK; (b) transducin-beta may serve as a (thio)phosphorylated NDPK intermediate; (c) transducin-NDPK is distinct from known NDPKs and may consist of multiple kinases or a single kinase with multiple regulatory domains.  (+info)

*List of drugs: E-El

... edetic acid (INN) edetol (INN) Edex. Redirects to Prostaglandin E1. edifoligide (USAN) edifolone (INN) edobacomab (INN) ... egtazic acid (INN) egualen (INN) elacridar (INN) elacytarabine (USAN, INN) elagolix (USAN, INN) elantrine (INN) elanzepine (INN ... redirects to rasburicase Elixicon Elixomin Elixophyllin ellagic acid (INN) Ellence Ellence (Pharmacia & Upjohn Company) ...

*Drinking water quality standards

4-Dioxane 50μg/l Edetic acid 600μg/l Ethylbenzene 300 μg/l Hexachlorobutadiene 0.6 μg/l Nitrilotriacetic acid 200μg/l ...

*List of MeSH codes (D02)

... edetic acid MeSH D02.241.081.038.455 --- egtazic acid MeSH D02.241.081.038.581 --- iodoacetic acid MeSH D02.241.081.038.581.400 ... edetic acid MeSH D02.092.782.258.368.257 --- egtazic acid MeSH D02.092.782.258.368.265 --- ethambutol MeSH D02.092.782.258. ... muramic acids MeSH D02.241.081.844.562 --- neuraminic acids MeSH D02.241.081.844.562.668 --- sialic acids MeSH D02.241.081.844. ... quinic acid MeSH D02.241.511.852 --- shikimic acid MeSH D02.241.511.902 --- sugar acids MeSH D02.241.511.902.107 --- ascorbic ...
Looking for Ethylenediamine tetraacetic acid? Find out information about Ethylenediamine tetraacetic acid. see chelating agents chelating agents . Certain organic compounds are capable of forming coordinate bonds with metals through two or more atoms of the... Explanation of Ethylenediamine tetraacetic acid
Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid such as compounds having the formula: ##STR1## wherein R is methyl or ethyl. Also, the method of cleaving DNA by contact with one of the above-identified molecules in the presence of ferrous ion and oxygen. The process of preparing said molecules by the reaction of P-carboxy methidium halide, p-carboxy ethidium halide, or other DNA intercalator or DNA groove binder with 1-3-diaminopropane followed by condensation with ethylenediamine tetraacetic acid. Distamycin-EDTA.Fe(II)(DE.FE(II)) contains EDTA attached to the amino terminus of the groove binder tripeptide (tris-N-methylpyrrolecarboxamide). De.Fe(II) cleaves DNA contiguous to a five base pair A+T rich sequence. This is a novel and unique molecule and superior in sequence specificity to the naturally occurring antitumor compound used in man, bleomycin which cleaves DNA at a two base pair recognition site. EDTA-distamycin
Product Details of EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt, EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt from China manufacturer on Hisupplier.com.
Looking for Calcium disodium ethylene diamine tetra-acetate? Find out information about Calcium disodium ethylene diamine tetra-acetate. see chelating agents chelating agents . Certain organic compounds are capable of forming coordinate bonds with metals through two or more atoms of the... Explanation of Calcium disodium ethylene diamine tetra-acetate
Effect of Chelation with Calcium Disodium EDTA on Haemato-biochemical and Trace Mineral Profile in Blood from Lead Exposed Calves - Chelation;$CaNa_2$EDTA;Lead;Calves;Sulfhydryl Groups;$\alpha$-Tocopherol;
Find quality suppliers and manufacturers of 60-00-4(Ethylenediaminetetraacetic acid) for price inquiry. where to buy 60-00-4(Ethylenediaminetetraacetic acid).Also offer free database of 60-00-4(Ethylenediaminetetraacetic acid) including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, solution etc.
The CSV is a delimited data format that has fields/columns separated by the semicolon character and records/rows separated by newlines. Fields that may contain a special character (semicolon, newline, or double quote), are enclosed in double quotes. For an easier handling, the list of Pre-registered substances is available in four parts ordered by EC number. They contain the same information as the following full list.. ...
Sequestering agents are added to maintain clarity and to promote calculus removal. Preferred sequestering agents include ethylene diamine tetraacetic acid ("EDTA"). The EDTA may be present in amounts of above 1% to 25% by weight of the composition, preferably about 17% to about 23% by weight of the composition, and most preferably about 19% to 21% by weight of the composition. EDTA also plays a role as an anti-bacterial component.. Surfactant ...
Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, most preferably isopropanol, and an additive, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. The use of an alcohol and additive solution can effectively reduce fouling of the catheter, particularly clotting and thrombus in intravascular catheters, as well as reduce the risk of infection. The risk of infection can be further reduced by employing a catheter body which is sufficiently porous to permit the anti-microbial solution of a lower alcohol and another anti-microbial or anti-coagulant compound to penetrate into the catheter body and preferably through the catheter into tissue surrounding the implanted catheter.
Oral chelation formlation with EDTA. Oral chelation: helps prevent hardening of the arteries; helps rejuvenate your cardiovascular system; improves circulation; helps remove lead, mercury, plus 20 other metals; reduces toxic lead and metal deposits and abnormal calcium deposits; improves liver function and kidney function; helps relieve symptoms of memory loss by increasing circulation of the brain; and, helps dissolve fats in plaque lined arteries. Oral Chelation Nutritional Complex with Ayurvedic Herbal BlendSix capsules supply:Vitamin A (retinyl palmitate) 10,000 I.UVitamin C (as ascorbic acid and zinc ascorbate) 640 mg.Elemental Potassium 210 mg.From Potassium Aspartate 684 mg.From Potassium Orotate 300 mg.Elemental Magnesium 330 mg.From Magnesium Aspartate 1400 mg.From Magnesium Orotate 714 mg.Elemental Zinc 25 mg.From Zinc Ascorbate 168 mgElemental Selenium 70 mcg.From Selenium Ascorbate 70 mg.Sodium 28 mg.EDTA (Ethylenediamine tetra-acetic acid) 800 mg.Disodium EDTA 200 mg.L-Glutathione, reduced
China EDTA 2na Used on Industrial Grade, Find details about China Disodium EDTA, Fertilizer from EDTA 2na Used on Industrial Grade - Qingdao Salus International Trade Co., Ltd.
BACKGROUND: Detergents and disinfectants are an emerging cause of work-related rhinitis and asthma. These products may contain ethylenediamine tetraacetic acid (EDTA). The authors report 10 cases of EDTA-related asthma and/or rhinitis. METHODS: Revie
Ferric sodium ethylenediaminetetraacetate (NaFeEDTA) enhances iron absorption in the presence of phytate. However, the amount of NaFeEDTA that would have to be added to a complementary food to provide the necessary intake of iron for an infant or you
Abstract: Stability of Human Salivary Lactate Dehydrogenase in the Present of Ethylenediaminetetraacetic Acid, Glycerol and Polyethylene Glycol at Various Temperatures: Preliminary Study
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EthyleneDiamine Tetra-acetic Acid (EDTA) 99% purity (Tech Grade)Chelating Agent Manufacturers for paper, household & industrial cleaning, water treatment,
Corneal epithelium removed from underlying extracellular matrix (ECM) extends numerous cytoplasmic processes (blebs) from the formerly smooth basal surface. If blebbing epithelia are grown on collagen gels or lens capsules in vitro, the basal surface flattens and takes on the smooth contour typical of epithelium in contact with basal lamina in situ. This study examines the effect of soluble extracellular matrix components on the basal surface. Corneal epithelia from 9- to 11-d-old chick embryos were isolated with trypsin-collagenase or ethylenediamine tetraacetic acid, then placed on Millipore filters (Millipore Corp., Bedford, Mass.), and cultured at the medium-air interface. Media were prepared with no serum, with 10% of calf serum, or with serum from which plasma fibronectin was removed. Epithelia grown on filters in this medium continue to bleb for the duration of the experiments (12-14 h). If soluble collagen, laminin, or fibronectin is added to the medium, however, blebs are withdrawn and ...
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A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive. [PubChem]
A nail cleanser containing sodium ethylenediamine tetraacetic acid, urea and water. When applied to nails it removes various stains such as tobacco, nail pigment, shoe polish, furniture polish and hair dyes.
Cultivation of H. polymorpha CBS 4732 (leu2-2) [32], C-105 (gcr1 catX) [22] and the recombinant producer of uricase was performed in flasks on a shaker (200 rpm) at 37°C in a medium containing (g L-1): (NH4)2SO4 - 3.5; KH2PO4 - 1.0; MgSO4 × 7H2O - 0.5; CaCl2 - 0.1; yeast extract - 6. Glucose (20 g L-1) was used as carbon source. For induction of uricase, the cells from the mid-exponential growth phase were washed once in the mineral medium and transferred to shake-flask cultures supplemented with 4 g L-1 urate as carbon source. Cultivation of the recombinant strain 22 was performed for 64 h. To prevent degradation of target enzyme, after washing, the cells were suspended in 30 mM Tris-HCl buffer (pH 8.9) containing 1 mM phenylmethylsulfonyl fluoride (PMSF) and 1 mM ethylenediaminetetraacetic acid (EDTA) followed by lyophilization. Before experiments, the lyophilized yeast cells were re-suspended to 30 mg mL-1 dry cell weight (DCW) in 30 mM Tris-HCl buffer, pH 8.9, containing 1 mM EDTA. ...
you are given a stock solution of edta at a concentration of 5mm how would you make a dilution of edta with a final, Hire Biology Expert, Ask Academics Expert, Assignment Help, Homework Help, Textbooks Solutions
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The goal of this thesis is to examine the distribution and diagenesis of carbohydrates in aquatic environments. The following questions are studied: what is the carbohydrate composition of sediment in different environments (e.g., deep-sea oxic; shallow-sea oxic; deep-sea anoxic; fresh-water anoxic; brackish-water anoxic, etc.)? How does the environment at the sediment-water interface affect the composition of the carbohydrate input? How do sedimentary carbohydrates compare to plankton carbohydrates? How do metal-carbohydrate interactions and biological degradation affect the diagenesis of carbohydrates in recent sediments? Can fossil carbohydrates be used as a means to elucidate paleo-environments? In order to investigate these questions in a quantitative manner, a liquid chromatographic sugar analyzer sensitive to 10-10 moles was constructed. Various extraction techniques, involving acid hydrolysis and EDTA treatment, were thoroughly examined to determine lability of sugars, sources of ...
Calcium disodium ethylenediamine-tetraacetate [(calcium ethylenedinitrilo) tetraacetate]; calcium disodium EDTA - AF, REG, 25 ppm - Fermented malt beverages - 172.120; Antigushing agent; MISC, 60 ppm - Spice extractives in soluble carriers; Color & flavor; 100 ppm - Pecan pie filling, promote color retention; 340 ppm - Clams (cooked-canned), promote color retention; 800 ppm - Dry Pinto beans, promote color retention; 310 ppm - Promote color retention in dried lima beans (cooked, canned); 275 ppm -Crabmeat (cooked- canned), retard struvite formation, promote color retention; 250 ppm - Shrimp (cooked-canned), retard struvite formation, promote color retention; 33 ppm -Promote flavor in carbonated soft drinks; 110 ppm - Promote color retention in canned white potatoes; 200 ppm - Mushrooms (cooked, canned); 220 ppm - In pickled cucumbers or pickled cabbage; To promote color, flavor & texture retention; 100 ppm - Promote color retention in artificially colored lemon-flavored and orange-flavored ...
EDTA chelation therapy is a nonsurgical treatment for heart disease. It can help you avoid heart and artery disease or could be an alternative to bypass surgery.
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Aged; Biological Markers; Creatinine; Cystatin C; Denmark; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Models, Biological; Multivariate Analysis; Predictive Value of Tests; Renal Dialysis; Reproducibility of Results; Time Factors; Urea ...
Adult, Anticoagulants, Blood Specimen Collection, Edetic Acid, Epidemiologic Studies, Female, Homocysteine, Humans, Male, Middle Aged, Sodium Fluoride, Temperature, Time Factors. ...
Find patient medical information for EDTA on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that have it.
EthyleneDiamineTetraacetic Acid (EDTA) is mainly used to sequester metal ions in aqueous solution.Also used in treating mercury and lead poisoning, in shampoos
InterFase Plus™ provides the same unique enzyme formulation as InterFase™ with the addition of ethylenediaminetetraacetic acid (EDTA). The presence of calcium,
Draw blood in a lavender-top (EDTA) tube(s), plasma gel tube(s) is not acceptable. Mix well, centrifuge at ambient temperature within one half hour of draw, and freeze immediately. Send 1 mL of EDTA plasma frozen in plastic vial. Complete and submit with specimen: 1. National Jewish Complement request form
plasma and serum - posted in ELISA and Immunoassay: will it make any difference if i use serum/edta plasma for hscrp (the kit sample requirement is citrated plasma)? but in my writing, i used serum for other biomarker.
Compositions having improved anti-plaque activity comprise a synergistic combination of a) a morpholinoamino alcohol, such as 3-(4-propylheptyl)-4-(2-hydroxyethyl) morpholine, and b) a chelating agent such as ethylenediaminetetraacetic acid.
Results: CVs for within-run and within-laboratory precision ranged from 0.7% to 7.7% and 1.7% to 8.6%, respectively, for samples containing 670-16039 ng/L. CVs for between-laboratory precision ranged from 7.1% to 8.9% (766-14289 ng/L). Recovery of GDF-15 was comparable for serum, Li-heparin plasma, K2- and K3-EDTA plasma, and citrated plasma, between 2 reagent lots, and on the cobas e 411 and cobas e 601 analyzers (Roche Diagnostics). GDF-15 concentrations in the clinically relevant range (400-3000 ng/L) measured with the Elecsys assay showed a good correlation and agreement with those measured by IRMA or ELISA. GDF-15 concentrations in apparently healthy individuals increased with age but did not vary by sex. ...
Recommended sample types are human EDTA plasma and serum. A range of additional sample types are compatible with the technology (PEA), including citrate plasma, heparin plasma, cerebrospinal fluid, (CSF), tissue and cell lysates, fine needle biopsis, microdialysis fluid, cell culture media, dried blood spots, synovial fluid, saliva, plaque extract and microvesicles. Please note that protein expression levels are expected to vary in different sample types. Certain assays are differentially affected by interfering substances such as hemolysate. Download any of our Data Validation documents or contact [email protected] for more information ...
Recommended sample types are human EDTA plasma and serum. A range of additional sample types are compatible with the technology (PEA), including citrate plasma, heparin plasma, cerebrospinal fluid, (CSF), tissue and cell lysates, fine needle biopsis, microdialysis fluid, cell culture media, dried blood spots, synovial fluid, saliva, plaque extract and microvesicles. Please note that protein expression levels are expected to vary in different sample types. Certain assays are differentially affected by interfering substances such as hemolysate. Download any of our Data Validation documents or contact [email protected] for more information ...
Quantikine Mouse C1qR1/CD93 ELISA Kit(MCD930). Sensitivity: 11.4 pg/mL. Validated for Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma. High precision and reproducibility. View product details.
Abcams MMP3 SimpleStep ELISA® Kit (ab189572) suitable for Cell culture supernatant, Serum, Heparin Plasma, EDTA Plasma, Citrate Plasma in human. Confidently…
ACP5 (Human) ELISA Kit is an ImmunoCapture Enzyme-Activity Assay for the quantitative measurement of human TRAP 5 in serum and EDTA plasma. (KA0041) - Products - Abnova
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* found in: EDTA, Solution, EDTA Solution is commonly used in biological and electrophoresis buffer systems. See the specifications tab for some of the..
در این پژوهش اثر اسکاونجر حفره EDTA در تسریع رنگبری رنگزای آبی مستقیم 71 به‌عنوان یک آلاینده سخت تجزیه‌پذیر در فرایند فتوکاتالیستی با استفاده از نانو ذرات دی‌اکسید تیتانیوم پوشش داده شده بر بستر سیمانی بررسی شد. با استفاده از 03/0 مولار EDTA، 75 میلی‌گرم در لیتر رنگزا در pH برابر 6 ، تحت تابش لامپ UV-C 60 وات طی مدت زمان 75 دقیقه رنگبری شد. این درحالی است که رنگزا تحت این شرایط و بدون حضور اسکاونجر در مدت زمان 225 دقیقه حذف شد، به ‌این ترتیب اثر تسریع‌کنندگی این اسکاونجر تأیید شد. سینتیک فرایند فتوکاتالیستی در حضور EDTA مرتبه اول با ثابت واکنش 05/0 بر دقیقه به‌دست آمد که 5/2
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They also suggest that coronary angiography may be helpful if initial stress testing is inconclusive or has conflicting results. In terms of SIHD treatment, the guideline writing group updated the recommendation for chelation therapy from "Class III: No Benefit" to "Class IIb" indicating the usefulness of chelation therapy is uncertain for reducing cardiovascular events in SIHD patients. "Although disodium ethylene diamine tetraacetic acid is approved by the U.S. Food and Drug Administration for specific indications, such as iron overload and lead poisoning, it is not approved for use in preventing or treating cardiovascular disease," they said. However, the writing group chose not to update the 2012 recommendation stating enhanced external counterpulsation (EECP) may be considered to help relieve refractory angina in SIHD patients. After re-examining the scientific evidence the group noted that, "in general, existing data, largely from uncontrolled studies, suggest a benefit from EECP among ...
Ethylenediamine tetraacetic acid (EDTA) was used as a nociceptive stimulus intradermally in the guinea pig. The responses evoked by EDTA included vocalization, biting and scratching at the site of injection and escape behavior. Nociception by EDTA was shown to be the result of its cation chelating activity. The suppression of EDTA-induced responses proved to be a rapid and effective antinociceptive test. The narcotic analgesics morphine, codeine, meperidine and methadone and the narcotic antagonist analgesics cyclazocine, cyclorphan, nalorphine and pentazocine were active. The slopes of the dose-response curves of the narcotic antagonist analgesics were significantly shallower than those of the narcotic analgesics. The test was highly specific for these analgesics. Antipyretic analgesics and various nonanalgesic drugs were inactive. ...
Benefits of Chelation Therapy. Cancer Treatment. Free radicals plays an important role on the onset of cancer. By removing the metallic anions from the blood stream, EDTA helps the cells to remain healthy and to help the damaged cells to heal. Some research has shown a decrease in the incidence of death by cancer after EDTA treatment.
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A method is described for estimating plasma renin activity by using renin substrate present in plasma. This method differs from other indirect renin assay methods by (1) incubation in the absence of ions thus establishing conditions for zero order kinetics for the reaction between endogeneous renin and substrate and (2) the use of angiotensinase inhibitors di-sodium ethylenediamine tetraacetic acid (EDTA) and d-isopropylfluorophosphate (DFP). Recoveries of renin added to plasma in levels similar to those occurring in plasma are 85% SD±7%.. The incubation was done at pH 5.5 which was shown to be the optimum for human renin reacting with human substrate.. By incubating human plasma samples with known quantities of human renin, evidence was obtained suggesting that factors other than enzyme or total substrate concentrations affect the velocity of angiotensin formation. This variability of reaction rate may be explained by the existence of an inhibitor or activator in this system or by a variation ...
It was previously reported that [3H]nitrendipine binding to a microsomal fraction from intestinal smooth muscle was dependent upon the presence of divalent metal cations (Bolger et al., J. Pharmacol. Exp. Ther. 225: 291-309, 1983). The effects of cations and calmodulin antagonists on [3H]nitrendipine binding in smooth and cardiac muscle have been studied further. Treatment of ileal and aortic smooth muscle and cardiac muscle with EDTA reduced specific [3H]nitrendipine binding by 70 to 95%. Microsomes from rabbit ventricle were more resistant to EDTA treatment than were those from ileal smooth muscle, but low concentrations of Ca++ (less than 10(-5) M) produced half-maximal restoration of binding in both tissues. The ability of cations at a concentration of 10(-3) M to restore binding to membranes from guinea-pig ileum was in the sequence, Ca++ = Sr++ greater than Mg++ = Mn++ = Co++ greater than Ba++ = Ni++ greater than Zn++ = Cd++ greater than La = Sm = Tm . In contrast to the activation of ...
Pharmaceutical Raw Material CAS: 987-65-5 ATP-Na2 /ATP Disodium Salt Adenosine CAS:987-65-5 ATP-Na2 /ATP disodium salt Product Name: Adenosine 5-triphosphate, disodium salt Synonyms: 5-ATP-Na2; Adenosine-5-triphosphate disodium salt hydrate;...
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Cytidine 5′-triphosphate disodium salt 36051-68-0 route of synthesis, Cytidine 5′-triphosphate disodium salt chemical synthesis methods, Cytidine 5′-triphosphate disodium salt synthetic routes ect.
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Distribution of Biotin Ethylene Diamine (BED). Coronal sections (paraffin embedded) through cortical wall surrounding lateral ventricles of E17, E19, and P0 mou
A product of the enzymatic oxidation of indole-3-acetic acid, 3-methyleneoxindole, is at least 50-fold more effective than indole-3-acetic acid in stimulating the growth of wheat (Triticum vulgare, red variety) coleoptiles. Ethylenediaminetetraacetic acid can antagonize the growth-stimulating properties of the parent compound, indole-3-acetic acid, presumably by chelating Mn+, which is required for the enzymatic oxidation of indole-3-acetic acid. The growth stimulating effect of 3methyleneoxindole, a product of the blocked reaction, on the other hand, is still evident in the presence of ethylenediaminetetraacetic acid. In the presence of 2-mercaptoethanol, indole-3-acetic acid fails to stimulate the elongation of wheat coleoptiles. The property of binding to sulfhydryl compounds including 2-mercaptoethanol is unique to 3-methyleneoxindole among indole-3-acetic acid and its oxidation products. These findings suggest that 3-methyleneoxindole is an obligatory intermediate in indole-3-acetic acid induced
Juicing and Raw Foods: EDTA Chelation: The Real "Miracle" Therapy for Vascular Disease The story of EDTA chelation therapy is as much political as it is medical. Co ...
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INGREDIENTS: WATER, VINEGAR, MODIFIED CORNSTARCH, SUGAR, HIGHFRUCTOSE CORN SYRUP, SOYBEAN OIL*, CONTAINS LESS THAN 2% OF SALT,NATURAL FLAVOR, CELLULOSE GEL, ARTIFICIAL COLOR, XANTHAN GUM,EGG YOLKS*, MUSTARD FLOUR, LACTIC ACID, PHOSPHORIC ACID,CELLULOSE GUM, VITAMIN E ACETATE, LEMON JUICE CONCENTRATE, DRIEDGARLIC, DRIED ONIONS, SPICE, YELLOW 6, BETA CAROTENE (COLOR),BLUE 1, POTASSIUM SORBATE AND CALCIUM DISODIUM EDTA TO PROTECT FLAVORCONTAINS: EGG.*TRIVIAL SOURCE OF FAT AND CHOLESTEROL. ...
Pseudothrombocytopenia is a condition in which blood has an abnormally low level of platelets because of an in-vitro problem with...
This report provides detailed analysis of worldwide markets for Uridine 5-Monophosphate Disodium Salt (CAS 3387-36-8) from 2011-2016, and provides extensive market forecasts (2016-2021) by region/country and subsectors. It covers the key technological and market trends in the Uridine 5-Monophosphate Disodium Salt (CAS 3387-36-8) market and further lays out an analysis of the factors influencing the…
Although chelation therapy with the drug disodium EDTA has been used for many years with limited evidence of efficacy for the treatment of coronary disease, a randomized trial that included patients with a prior heart attack ...
NTA or EDTA is agglomerated using a liquid active detergent composition such as an aqueous solution of polyacrylic acid. This agglomerated NTA/EDTA can then be combined with other detergent active compositions to form a detergent which does not cake easily. The detergent can also be compressed to form a tableted detergent.
* found in: Ethylenediamine, 99%, Earles Balanced Salts Solution (10X), Ethylenediaminetetraacetic acid disodium salt dihydrate, 99+%, Eriochrome Black T,..
Instructions for use: After cleansing, gently wipe pad on face and neck in upward and outward motion Dispose after single use Follow with [SUPERSTART id669370] for best results Use two to three times a week, as needed Ingredients: Water/Aqua/Eau, Glycolic Acic, Arginne, Triethanolamine, Saccharide Isomerate, Lactobacillus Ferment, Citric Acid, Citrus Aurantium Dulcis (Orange) Peel Oil, Disodium EDTA, Glycine, Sodium Citrate, Sodium PCA
Find and order plasmas and products like this Bovine/Calf Plasma (Sterile In Potassium EDTA) on www.antibodies-online.com. Order product ABIN1044453.
Hi, I make up 3 liters of formic acid and 3 liters of Sodium Formate at a time because it is easier to handle and store. You probably know you only put them together in equal parts when you put them on a specimen. The formate takes a bit of stirring to desolve. I make them up in used ETOH jugs. Sodium Formate 204.6g in 3 liters of water. Formic Acid 1050 Formic and 1950 of water. I am going to start to use EDTA on my specimens for IHC. I just got a free sample and will test it on larger specimens..pig parts. I imagine it will take a while. I may ask for some advice. Hope this helps. Trisha On Thu, 6 Dec 2001, Harvey, Jennifer wrote: > > > > ---------- > > From: Harvey, Jennifer > > Sent: Tuesday, December 4, 2001 4:21 PM > > To: Histonet > > Subject: Buffered Formic Acid Decal Recipe > > > > Histonet, > > > > I am looking for a buffered formic acid decal recipe to decal mouse bones > > that we are going to do immuno on. We usually use EDTA but this project we > > dont have the time. > > > > ...
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A monoclonal antibody, RE2, raised by immunizing a rat with cell lysate of a mouse T cell clone, was found to directly kill interleukin 2-dependent T cell clones without participation of serum complement. Fab fragments of RE2 had no cytolytic activity, while the cross-linking of Fab fragments with anti-rat immunoglobulin reconstituted the cytotoxicity. The cytotoxicity was temperature dependent: the antibody could kill target cells at 37 degrees C but not at 0 degrees C. Sodium azide, ethylenediaminetetraacetic acid, and forskolin did not affect the cytolytic activity of RE2, while the treatment of target cells with cytochalasin B and D completely blocked the activity. This suggested that the cell death involves a cytoskeleton-dependent active process. Giant holes on the cell membrane were formed within 5 minutes after the treatment with RE2, as observed by scanning electron microscopy. There was no indication of DNA fragmentation nor swelling of mitochondria during the cytolysis, suggesting ...
FPROP : Submit only 1 of the following specimens:   Serum Draw blood in a plain, red-top tube(s).  (Serum gel tube is not acceptable.) Spin down and send 3 mL of serum refrigerate in plastic vial. Note:       1. Indicate serum on request form.                 2. Label specimen appropriately (serum).     Plasma Draw blood in a lavender-top (EDTA) tube(s). (Plasma gel tube is not acceptable.) Spin down and send 3 mL of EDTA plasma refrigerate in plastic vial. Note:     1. Indicate plasma on request form.                 2. Label specimen appropriately (plasma).
Submit only 1 of the following specimens:. Serum. Draw blood in a plain, red-top tube(s). Spin down and send 1 mL of serum refrigerated in plastic vial.. Plasma. Draw blood in an EDTA lavender-top or pink-top tube(s). Spin down and send 1 mL of EDTA plasma in refrigerated in plastic vial.. ...
Specimen must arrive within 1 hour of draw.. Draw blood in a lavender-top (EDTA) tube(s). Spin down, refrigerate within 1 hour of draw, and send 1 mL (minimum volume: 0.5 mL) of EDTA plasma refrigerated in a tightly-stoppered tube. If there is a delay in transport of ,7 hour, send specimen frozen in plastic vial. Note: Specimen may only be thawed once for viability.. ...
Mouse Apolipoprotein E SimpleStep ELISA® Kit is a highly sensitive (130 pg/ml), single-wash 90 min immunoassay suitable for Serum, Heparin Plasma, EDTA Plasma, Citrate Plasma samples.
The sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ IL-17A/F Heterodimer Immunoassay Kit unparalleled performance in the quantification of IL-17A/F in human EDTA plasma and serum. Find MSDS or SDS, a COA, data sheets and more information.
This test is intended for use in conjunction with clinical presentation and other laboratory markers of disease progress for the clinical management of HIV-1 infected patients. The test can be used to assess patient prognosis by measuring the baseline HIV-1 RNA level or to monitor the effects of antiretroviral therapy by measuring changes in EDTA plasma HIV-1 RNA levels during the course of antiretroviral treatment.
In article ,9508080226.AA12954 at gipac.shinshu-u.ac.jp,, ,tnakane at GIPAC.SHINSHU-U.AC.JP (tokio nakane) wrote: , ,, Hello, ,, We are currently trying to clone a G protein-coupled receptor by panning ,method. ,, We constructed a rat brain cDNA library (pME18S vector; SR-alpha promoter) ,, and transfected the library to COS-7 cells by DEAE dextran method. After ,, 72 hrs, we could not detach cells from dishes by the treatment with PBS and ,, 5 mM EDTA at 37 C for 30 min. The untransfected cells were easily detached ,, by the treatment. Any advice would be much appreciated. ,, ,, Tokio , ,Dear Tokio, , ,You might try 293 cells (human embryonic kidney). They are generally ,easier to detach from plates. , ,Cliff Beall Cliffs suggestion is well-taken, but I dont think its what Tokio should do. The higher he can get expression levels, the more efficient his panning will be. The SR-alpha promoter contains most of the SV40 origin, and so should give exteremely high levels in COS-7 cells, which are ...
Product Number , 52620391. CAS Number , 33430-61-4. EC , 251-517-5. Molecular Formula , C10H12N5Na2O7P.xH2O. Molecular Weight , 391.18. Storage Temp , Harmonized Tariff code , 29349990. Signal Word , ...
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Composition of (1X) TBE Buffer is 0.089M Tris Base; 0.089M Boric Acid; 0.002M EDTA, Free Acid; Final pH 8.3. Made using EDTA, Free Acid. DNase, Protease, RNase free ...
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Heres something that I find to be most disturbing! http://www.webmd.com/vitamins-supplements/ingredientmono-1032-EDTA.aspx?activeIngredientId=1032&activeIngredientName=EDTA EDTA Other Names: Ac...
U koordinacionoj hemiji, EDTA4- je član familije liganda poliamino karboksilnih kiselina. EDTA4- obično vezuje metalne katjone putem dva amina i četiri karboksilata. Mnogi od rezultujućih koordinacionih jedinjenja imaju oktaedralnu geometriju. Ti oktaedralni kompleksi su hiralni. Pokazano je da se anjon [Co(EDTA)]− može razdvojiti u enantiomere.[9] Mnogi kompleksi EDTA4- poprimaju kompleksnije strukture usled (i) formiranja dodatnih veza sa vodom, i.e. sedam-koordinatni kompleksi, ili (ii) zamene jednog karboksilata vodom.[10] EDTA formira posebno jake komplekse sa Mn(II), Cu(II), Fe(III), Pb (II) i Co(III).[11]. Nekoliko osobina EDTA kompleksa je relevantno za njihove primene. Zbog njihove visoke gustine veza na jednom atom ovi ligandi imaju visok afinitet za metalne katjone:. ...
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TEIXEIRA, Pedro A et al. Cytotoxicity assessment of 1% peracetic acid, 2.5% sodium hypochlorite and 17% EDTA on FG11 and FG15 human fibroblasts. Acta odontol. latinoam. [online]. 2018, vol.31, n.1, pp.11-15. ISSN 1852-4834.. The aim of this study was to evaluate the cytotoxic effects of 2. 5% sodium hypochlorite (NaOCl), 17% ethylenediamine tetraacetic acid (EDTA), and 1% peracetic acid (PAA) on human fibroblasts. FG11 and FG15 cell lines were cultured in 24-well cell culture plates for cell proliferation assessment and 96-well cell culture plates for the methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay; Dulbeccos modified Eagles medium (DMEM) was used as control data. The experimental solutions were used at 0. 01%, 0. 05%, and 0. 1% dilutions and assessed at 1-, 2-, and 4-hour intervals. Data were subjected to statistical analysis by two-way analysis of variance (ANOVA), followed by the Bonferroni test at a significance level of p ,0. 05. The assessment of cell proliferation in this ...
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Retinas from Cx3cr1gfp/+ mice, as well as retinas and choroids from C57BL/6J wild-type (WT) mice, were dissected and divided into radial portions to be used in whole-mount immunofluorescence staining, as previously described.34 Tissue whole-mounts were incubated in 20 mM ethylenediaminetetraacetic acid for 30 minutes at 37°C and blocked in 0.3% Triton X-100, 3% bovine serum albumin in PBS for 30 minutes at room temperature before antibody incubation. Tissues were then incubated with rabbit anti-mouse ionized calcium-binding adaptor molecule 1 (Iba-1, 1:400; Wako Pure Chemical Industries, Osaka, Japan) and rat anti-mouse MHC class II (M5/114.15.2, 1:400; BD Pharmingen, San Diego, CA, USA). Incubations were carried out for four hours at room temperature, followed by overnight incubation at 4°C. The following day, whole-mounts were washed three times in PBS and incubated with biotinylated goat anti-rat (1:400; Amersham Biosciences, Buckinghamshire, UK) diluted in blocking buffer, for two hours at ...
BACKGROUND: In the BioDeNOX technology for NOX removal from flue gas, bioreduction of Fe(II)EDTA-NO and Fe(III)EDTA are core processes. In this study, a newly isolated strain, Paracoccus denitrificans, was used to reduce Fe(II)EDTA-NO with glucose and Fe(II)EDTA as donor electrons. To better understand the change law of Fe(II)EDTA, the process of Fe(II)EDTA-NO reduction by P. denitrificans with glucose and Fe(II)EDTA as electron donors was investigated, and the factors that might affect Fe(II)EDTA concentration were studied.. RESULTS: For the bioreduction process of Fe(II)EDTA-NO, P. denitrificans could use glucose and Fe(II)EDTA as electron donors. At different stages, primary electron donors were different, thereby affecting the concentration of Fe(II)EDTA in the system. It was also proved that this strain not only reduced Fe(III)EDTA with glucose as the electron donor but also secreted several substances that reacted with Fe(III)EDTA, resulting in increased Fe(II)EDTA concentration in the ...
Ballal NV, Tweeny A, Baumgartner JC, Ginjupalli K, Saraswathin V. Effect of maleic acid and theylenediaminetetraacetic acid on the shear bond strenth of RealSeal SE sealer to root canal dentin. Eur J Prosthodont Restor Dent. 2013;21(4):152-6.. Centers for Disease Control and Prevention (CDC). Deaths associated with hypocalcemia from chelation therapy--Texas, Pennsylvania, and Oregon, 2003-2005. MMWR Morb Mortal Wkly Rep. 2006;55(8):204-7.. Chappell LT. Should EDTA chelation therapy be used instead of long-term clopidogrel plus aspirin to treat patients at risk from drug-eluting stents? Altern Med Rev. 2007 Jun;12(2):152-8. Review.. Escolar E, Lamas GA, Mark DB, et al. The effect of an EDTA-based chelation regimen on patients with diabetes mellitus and prior myocardial infarction in the Trial to Assess Chelation Therapy (TACT). Circ cardiovasc Qual Outcomes. 2014;7(1):15-24.. Evans DAP, Tariq M, Sujata B, McCAnn G, Sobki S. The effects of magnesium sulphate and EDTA in the hypercholesterolaemic ...
0089]In those embodiments where the polyimine compound is defined by the formula II with n being equal to 2, the polyimine compounds may be referred to as heterocyclic bis-imine compounds. Specific examples of heterocyclic bis-imine compounds include N,N-bis(2-pyridylmethylidene)ethylenediamine, N-(2-pyridylmethylidene)-N-(benzylidene)ethylene diamine, N,N-bis(3-pyridylmethylidene)ethylene diamine, N-(3-pyridylmethylidene)-N-(benzylidene)ethylenediamine, N,N-bis(4-pyridylmethylidene)ethylenediamine, N-(4-pyridylmethylidene)-N-(benzylidene)ethylenediamine, N,N-bis(pyrazinylmethylidene)ethylenediamine, N,N-bis(2-pyrimidinylmethylidene)ethylenediamine, N,N-bis(3-pyridazinylmethylidene)ethylene diamine, N,N-bis(1-methyl-2-pyrrolylmethylidene)ethylene diamine, N,N-bis(1-methyl-2-imidazolylmethylidene)ethylenediamine, N,N-bis(1-methyl-3-pyrazolylmethylidene)ethylenediamine, N,N-bis(2-furylmethylidene)ethylene diamine, N,N-bis(3-furylmethylidene)ethylene diamine, ...
[150 Pages Report] Check for Discount on 2016 Global and Chinese Ethylene Diamine Acid Phosphate (CAS 14852-17-6) Industry Market Research Report report by Prof Research. The Global and Chinese Ethylene Diamine Acid Phosphate Industry, 2011-...
1. A simple new assay for glycerylphosphorylcholine phosphodiesterase is described, in which radioactive glycerylphosphorylcholine is used as substrate and the reaction products are separated by adsorption on an anion-exchange resin. 2. Rat liver subcellular fractions contained both particulate (58%) and soluble (42%) glycerylphosphorylcholine phosphodiesterase. Both activities released free choline from glycerylphosphorylcholine. 3. The particulate glycerylphosphorylcholine phosphodiesterase was recovered mainly in the nuclear and microsomal fractions and showed a distribution similar to those of 5′-nucleotidase and alkaline phosphodiesterase I, both of which are constituents of the liver plasma membrane. 4. During purification of plasma membranes glycerylphosphorylcholine phosphodiesterase, 5′-nucleotidase and alkaline phosphodiesterase I showed largely similar behaviour, indicating that glycerylphosphorylcholine phosphodiesterase is also localized in liver plasma membranes. Slight ...
Calcium channel antagonist binding sites have been labeled in cerebral cortex, heart, ileum, and skeletal muscle with [3H]nitrendipine. While the dissociation constants of the site from cortex, heart, and ileum are similar, KD approximately equal to 0.1-0.2 nM, the value in skeletal muscle is 2 nM. This difference is affinity is also reflected in the Ki values of dihydropyridine calcium channel antagonists, nifedipine, nimodipine, PY108068, SKF24260, and nisoldipine, and the calcium channel agonist CGP 28392, all of which show lower affinity for the skeletal muscle binding site. The diphenylalkylamine calcium channel antagonists, lidoflazine, cinnarizine, flunarizine, and prenylamine, however, show a 3- to 10-fold increase in affinity in skeletal muscle relative to the other three tissues. EDTA treatment of membranes decreases binding in cortex, heart, and ileum but increases binding in skeletal muscle. These changes are reversible upon addition of CaCl2, SrCl2, or BaCl2. The different ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Instructions for use: Apply Facial Treatment Essence with cotton ball to face and neck, followed by Facial Treatment Clear Lotion For an extra boost use the Facial Treatment Mask Facial Treatment Essence: 75ml/2.5 fl.oz; Facial Treatment Clear Lotion: 30ml/ 1 fl.oz Facial Treatment Clear Lotion Ingredients: Water, Saccharomycopsis Ferment Filtrate*, Butylene Glycol, Polysorbate 20, Glycerin, Sodium Hyaluronate, PEG-150, Cellulose Gum, Disodium EDTA, Citric Acid, Salicylic Acid, Lactic Acid, Malic Acid, Sodium Citrate, Sodium Benzoate, Methylparaben Facial treatment Essence Ingredients: Galactomyces Ferment Filtrate, Butylene Glycol, Pentylene Glycol, Water, Sodium Benzoate, Methylparaben, Sorbic Acid Facial Treatment Mask Ingredients: Water, Saccharomycopsis Ferment Filtrate*, Butylene Glycol, Xanthan Gum, Sodium Salicylate, Methylparaben, Disodium EDTA
Introduction. Microorganisms are the major causative factor associated with endodontic treatment failure.1,2 The success of endodontic treatment depends on the reduction or elimination of bacteria present in the root canal system. Residual pulpal tissue, bacteria, and dentine debris may persist in the irregularities of root canal systems, even after meticulous mechanical preparation.3 Therefore, irrigant solutions should be used in combination with canal preparation.4-6 Root canal irrigants are used during chemomechanical procedures not only as antimicrobial agents but also to flush out loose debris, to lubricate the dentinal walls, and to dissolve organic compounds in the canal.7, 8 Chemomechanical preparation is one of the most important phases of endodontic treatment and irrigants such as sodium hypochlorite (NaOCl), citric acid, and ethylene diamine tetra-acetic acid (EDTA) are commonly used. The efficacy of these procedures also depends upon the vulnerability of the species involved.9 Many ...

Edetic Acid - DrugBankEdetic Acid - DrugBank

Cilostazol may increase the anticoagulant activities of Edetic Acid.. Approved. Citric Acid. Edetic Acid may increase the ... Edetic Acid may increase the anticoagulant activities of Protein C.. Approved. Protein S human. Edetic Acid may increase the ... Deoxycholic Acid. The risk or severity of adverse effects can be increased when Edetic Acid is combined with Deoxycholic Acid. ... Edetic Acid may increase the anticoagulant activities of Dextran 40.. Approved. Dextran 70. Edetic Acid may increase the ...
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Edetic acid - Substance Information - ECHAEdetic acid - Substance Information - ECHA

Edetic acid. ↓Other names: Regulatory process names [3] Trade names [12] Other names [1] IUPAC names [28] ... Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid, Ethylenediaminetetraacetic acid, ... Ethylenediamine tetraacetic acid * ethylenediamine-N,N-tetraacetic acid; (2,2,2,2-(Ethane-1,2-diyldinitrilo)tetraacetic ... 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid * disodium 2-[2-[bis(carboxymethyl)amino]ethyl-(2-oxido-2- ...
more infohttps://echa.europa.eu/fr/substance-information/-/substanceinfo/100.000.409

Edetic acid - Registration Dossier - ECHAEdetic acid - Registration Dossier - ECHA

EDTA is resistant to hydrolysis, neither strong acids nor alkalis cause any degradation. However photodegradation in natural ...
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Edetic Acid
      - EDTA
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Edetic Acid: A chelating agent (CHELATING AGENTS) that sequesters a variety of polyvalent cations. It is used in pharmaceutical ... Edetic Acid, Calcium Salt; Edetic Acid, Calcium, Sodium Salt; Edetic Acid, Chromium Salt; Edetic Acid, Dipotassium Salt; Edetic ... Edetic Acid, Magnesium Salt; Edetic Acid, Monopotassium Salt; Edetic Acid, Monosodium Salt; Edetic Acid, Potassium Salt; Edetic ... Acid, Disodium Salt; Edetic Acid, Disodium Salt, Dihydrate; Edetic Acid, Disodium, Magnesium Salt; Edetic Acid, Disodium, ...
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Septefx (Alcohol Anhydrous; Chlorhexidine Gluconate; Edetic Acid) CommseptSeptefx (Alcohol Anhydrous; Chlorhexidine Gluconate; Edetic Acid) Commsept

Liquid; Disinfectant (Hospital / Healthcare Facilities); Alcohol Anhydrous 70.5%; Chlorhexidine Gluconate 0.2%; Edetic Acid 0.2 ... Liquid; Disinfectant (Hospital / Healthcare Facilities); Alcohol Anhydrous 70.5%; Chlorhexidine Gluconate 0.2%; Edetic Acid 0.2 ...
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Chelate agent Edetic acid disodium salt EDTA Acid By Shijiazhuang Tuhong Biotech Co., Ltd, ChinaChelate agent Edetic acid disodium salt EDTA Acid By Shijiazhuang Tuhong Biotech Co., Ltd, China

English Name]: Ethylene diamine tetraacetic acid (EDTA) [Molecular Fomula]: C10H16N2O8 [Molecular Weight]: M=292.24 [CAS No]: ... Classification : Sodium Organic Salt Other Names : EDTA Acid MF : C10H16N2O8 Grade Standard : Industrial Grade Purity (%) : 99% ...
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Search Results for Edetic Acid - Ingentium News MagazineSearch Results for "Edetic Acid" - Ingentium News Magazine

Search Results for: Edetic Acid. January 6, 2019. January 6, 2019. Evaluation of para-Aminosalicylic Acid as a Substrate of ... Expression of a recombinant, 4′-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli. Tuberculosis ... Publication date: May 01, 2017 para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to ... Publication date: Apr 27, 2018 Fatty acid synthase 1 (FAS I) from Mycobacterium tuberculosis (Mtb) is an essential protein and ...
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EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt from China...EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt from China...

EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt from China ... Product Details of EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt, ... EDTA disodium salt CAS 6381-92-6 disodium dihydrogen ethylenediaminetetraacetate Edetic acid disodium salt Payment Terms:. T/T, ... Disodium Salt Disodium Phosphate Disodium Phosphate Dsp Inorganic Acid Salt Acetic Acid Sodium Salt Salt More>> ...
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Sodium Calciumedetate Animalcare - Drugs.comSodium Calciumedetate Animalcare - Drugs.com

Edetic Acid. Edetic Acid calcium disodium (a derivative of Edetic Acid) is reported as an ingredient of Sodium Calciumedetate ...
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EUR-Lex - 52011SC1544 - EN - EUR-LexEUR-Lex - 52011SC1544 - EN - EUR-Lex

60-00-4 ,, Edetic acid (EDTA) ,, Risk assessment conclusion iii for aquatic environment, but evidence suggested risk ratio ... 1066-51-9 ,, Amino-methyl phosphonic acid (AMPA) ,, Identified in the INERIS report as potentially responsible for failures in ... Perfluorooctane sulfonic acid and its salts (PFOS) and perfluorooctane sulfonyl fluoride ,, UK ... 1066-51-9 ,, Aminomethylphosphonic acid (AMPA) ,, X ,, 89-92 1071-83-6 ,, Glyphosate (incl trimesium aka sulfosate) ,, X ,, 69- ...
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N,N-bis(2-hydroxybenzyl)ethylenediamine-N,N-diacetic acid. Edetic Acid. Chelating Agents. Sequestering Agents. Molecular ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT03388346?term=%28NOT+NOTEXT%29+%5BCITATIONS%5D&rank=22

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Aloe Barbadensis (Aloe Vera) Leaf Extract, Benzophenone-3, Citric Acid, Cocamidopropyl Betaine, Cocamidopropylamine Oxide, ... CITRIC ACID ACETATE. COCAMIDOPROPYL BETAINE. COCAMIDOPROPYLAMINE OXIDE. WATER. EDETIC ACID. GLYCERIN. HAMAMELIS VIRGINIANA LEAF ...
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Edetic Acid. Pentetic Acid. Micronutrients. Growth Substances. Physiological Effects of Drugs. Anticoagulants. Calcium ... EDTA chelation therapy involves repeated administrations of a synthetic amino acid to reduce atherosclerotic plaque and other ...
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Correlation Between SUV on 68Ga-HBED-CC-PSMA and Gleason Score in Prostate Cancer - Full Text View - ClinicalTrials.govCorrelation Between SUV on 68Ga-HBED-CC-PSMA and Gleason Score in Prostate Cancer - Full Text View - ClinicalTrials.gov

Edetic Acid. Anticoagulants. Calcium Chelating Agents. Chelating Agents. Sequestering Agents. Molecular Mechanisms of ...
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A Pilot Study of 68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer -...A Pilot Study of 68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer -...

Edetic Acid. Molecular Mechanisms of Pharmacological Action. Anticoagulants. Calcium Chelating Agents. Chelating Agents. ...
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Category:Carboxylic acids - Wikimedia CommonsCategory:Carboxylic acids - Wikimedia Commons

For the conjugate bases of carboxylic acids, RCO2−, see Category:Carboxylate ions. For salts of carboxylic acids, RCO2M, see ... Molecules containing such a functional group are also called carboxylic acids or organic acids, although there are other ... In chemistry, carboxylic acids are acids characterized by the presence of a carboxyl group. ... carboxylic acid-transporting ATPase activity (cargo),. carboxylic acid transmembrane transporter activity (cargo),. carboxylic ...
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DailyMed - A.H.C. COLLAGEN CREAM- adenosine 0.04% creamDailyMed - A.H.C. COLLAGEN CREAM- adenosine 0.04% cream

EDETIC ACID. N-ACETYLGLUCOSAMINE. CREATINE. NIACINAMIDE. HYDROGENATED SOYBEAN LECITHIN. FD&C YELLOW NO. 6 ...
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Law Document English View | Ontario.caLaw Document English View | Ontario.ca

Salicylic acid and. its salts - in topical preparations in concentrations up to/including 40 per cent ... Lactic acid (CDSS) (in preparations in concentrations greater than 10 per cent - Schedule 3) ... Acetylsalicylic acid - when sold in standard unit doses of 325 mg 51 or less ...
more infohttps://www.ontario.ca/laws/regulation/110058?search=Drug+and+Pharmacies++Regulation+Act

Law Document English View | Ontario.caLaw Document English View | Ontario.ca

Salicylic acid and its salts - in topical preparations in concentrations up to/including 40 per cent ... Lactic acid (CDSS) (in preparations in concentrations greater than 10 per cent - Schedule 3) ... Acetylsalicylic acid - when sold in standard unit doses of 325 mg 51 or less ...
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Olemasolevate ainete määrusest pärit teave - ECHAOlemasolevate ainete määrusest pärit teave - ECHA

Edetic acid 200-449-4 60-00-4 1 Aniline 200-539-3 62-53-3 1 ... Acrylic acid 201-177-9 79-10-7 1 Chloroacetic acid 201-178-4 79 ...
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TLR7 Gene - GeneCards | TLR7 Protein | TLR7 AntibodyTLR7 Gene - GeneCards | TLR7 Protein | TLR7 Antibody

Edetic Acid. Approved, Vet_approved. *MalaCards. *Medline Plus. Pharma. 102. ANA971. Investigational. *MalaCards ... 1049 amino acids. Molecular mass:. 120922 Da. Quaternary structure:. *Interacts with MYD88 via their respective TIR domains. ...
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Low calcium diet in dogs causes a greater increase in parathyroid function measured with an intact hormone than with a...Low calcium diet in dogs causes a greater increase in parathyroid function measured with an intact hormone than with a...

Edetic Acid / pharmacology. Female. Hydroxyproline / urine. Parathyroid Glands / drug effects, physiology*. Parathyroid Hormone ... 60-00-4/Edetic Acid; 7440-70-2/Calcium; EC 3.1.3.1/Alkaline Phosphatase ...
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Use of lysozyme, nisin, and EDTA combined treatments for maintaining quality of packed ostrich patties.Use of lysozyme, nisin, and EDTA combined treatments for maintaining quality of packed ostrich patties.

... and ethylene diamine tetraacetic acid (EDTA) combination treatments (Mix(1): 250 ppm lysozyme, 250 ppm nisin, 5 mM EDTA; Mix(2 ... 0/Anti-Bacterial Agents; 0/Antioxidants; 0/Thiobarbituric Acid Reactive Substances; 1414-45-5/Nisin; 9G34HU7RV0/Edetic Acid; EC ... Edetic Acid / pharmacology*. Enterobacteriaceae / drug effects, isolation & purification. Food Microbiology*. Food Packaging / ...
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  • EDTA chelation therapy involves repeated administrations of a synthetic amino acid to reduce atherosclerotic plaque and other mineral deposits throughout the cardiovascular system. (clinicaltrials.gov)
  • Evaluation of para-Aminosalicylic Acid as a Substrate of Multiple Solute Carrier Uptake Transporters and Possible Drug Interactions with Nonsteroidal Anti-inflammatory Drugs In Vitro. (ingentium.com)
  • Publication date: May 01, 2017 para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to treat multidrug-resistant and extensively drug-resistant tuberculosis for more than 60 years. (ingentium.com)
  • Publication date: Apr 27, 2018 Fatty acid synthase 1 (FAS I) from Mycobacterium tuberculosis (Mtb) is an essential protein and a promising drug target. (ingentium.com)
  • Specification of disodium edta dihydrate English name: Ethylene diamine tetraacetic acid disodium salt( EDTA -2NA) Molecular Fomula. (chinacsw.com)
  • EDTA Disodium Salt Dihydrate Micronutrient Fertilizer Cas 6381-92-6 Quick Detail: Ethylenediaminetetraacetic acid ( EDTA ) is a chelating agent produced as a series of salts. (chinacsw.com)
  • fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine ethoxylates, castor oil ethoxylates and sulfosuccinates of C18 (unsatd. (europa.eu)