Dystonia
An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
Dystonic Disorders
Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.
Dystonia Musculorum Deformans
A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and face. The hands are often spared, however, sustained axial and limb contractions may lead to a state where the body is grossly contorted. Onset is usually in the first or second decade. Familial patterns of inheritance, primarily autosomal dominant with incomplete penetrance, have been identified. (Adams et al., Principles of Neurology, 6th ed, p1078)
Torticollis
A symptom, not a disease, of a twisted neck. In most instances, the head is tipped toward one side and the chin rotated toward the other. The involuntary muscle contractions in the neck region of patients with torticollis can be due to congenital defects, trauma, inflammation, tumors, and neurological or other factors.
Anti-Dyskinesia Agents
Meige Syndrome
A syndrome characterized by orofacial DYSTONIA; including BLEPHAROSPASM; forceful jaw opening; lip retraction; platysma muscle spasm; and tongue protrusion. It primarily affects older adults, with an incidence peak in the seventh decade of life. (From Adams et al., Principles of Neurology, 6th ed, p108)
Globus Pallidus
Muscle Cramp
Movement Disorders
Deep Brain Stimulation
Botulinum Toxins
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Neuromuscular Agents
Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS.
Hand
Molecular Chaperones
Botulinum Toxins, Type A
Nocturnal Paroxysmal Dystonia
A parasomnia characterized by paroxysmal episodes of choreoathetotic, ballistic, dystonic movements, and semipurposeful activity. The episodes occur during non-rapid eye movement sleep and typically recur several times per night. (Neurology 1992 Jul;42(7 Suppl 6):61-67; Adams et al., Principles of Neurology, 6th ed, p391)
Entopeduncular Nucleus
A portion of the nucleus of ansa lenticularis located medial to the posterior limb of the internal capsule, along the course of the ansa lenticularis and the inferior thalamic peduncle or as a separate nucleus within the internal capsule adjacent to the medial GLOBUS PALLIDUS (NeuroNames, http://rprcsgi.rprc. washington.edu/neuronames/ (September 28, 1998)). In non-primates, the entopeduncular nucleus is analogous to both the medial globus pallidus and the entopeduncular nucleus of human.
Levodopa
The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
GTP Cyclohydrolase
(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).
Basal Ganglia Diseases
Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
Basal Ganglia
Trihexyphenidyl
Chorea
Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
Complex Regional Pain Syndromes
Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
Dyskinesia, Drug-Induced
Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
Electromyography
Essential Tremor
A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)
Spasm
Facial Muscles
Sensation Disorders
Age of Onset
Dyskinesias
Abnormal involuntary movements which primarily affect the extremities, trunk, or jaw that occur as a manifestation of an underlying disease process. Conditions which feature recurrent or persistent episodes of dyskinesia as a primary manifestation of disease may be referred to as dyskinesia syndromes (see MOVEMENT DISORDERS). Dyskinesias are also a relatively common manifestation of BASAL GANGLIA DISEASES.
Parkinsonian Disorders
A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
MedlinePlus
Muscle Contraction
Electronic Mail
Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Editorial Policies
Authorship
Postal Service
Internet
Neck Muscles
Voice Disorders
Algorithms
Health Services Needs and Demand
DYT1 mutation in French families with idiopathic torsion dystonia. (1/432)
A GAG deletion at position 946 in DYT1, one of the genes responsible for autosomal dominant idiopathic torsion dystonia (ITD), has recently been identified. We tested 24 families and six isolated cases with ITD and found 14 individuals from six French families who carried this mutation, indicating that 20% of the affected families carried the DYT1 mutation. Age at onset was always before 20 years (mean, 9+/-4 years). Interestingly, the site of onset was the upper limb in all but one patient. Dystonia was generalized in seven patients and remained focal or segmental in three patients. The absence of common haplotypes among DYT1 families suggests that at least six independent founder mutations have occurred. In addition, one Ashkenazi Jewish family carried the common haplotype described previously in Ashkenazi Jewish patients, but it was absent in the other family. Moreover, the dystonia remained focal in the latter family when compared with the usual generalized phenotype in patients with the common Ashkenazi Jewish haplotype. This indicates that there are at least two founder mutations in this population. (+info)Human deafness dystonia syndrome is a mitochondrial disease. (2/432)
The human deafness dystonia syndrome results from the mutation of a protein (DDP) of unknown function. We show now that DDP is a mitochondrial protein and similar to five small proteins (Tim8p, Tim9p, Tim10p, Tim12p, and Tim13p) of the yeast mitochondrial intermembrane space. Tim9p, Tim10p, and Tim12p mediate the import of metabolite transporters from the cytoplasm into the mitochondrial inner membrane and interact structurally and functionally with Tim8p and Tim13p. DDP is most similar to Tim8p. Tim8p exists as a soluble 70-kDa complex with Tim13p and Tim9p, and deletion of Tim8p is synthetically lethal with a conditional mutation in Tim10p. The deafness dystonia syndrome thus is a novel type of mitochondrial disease that probably is caused by a defective mitochondrial protein-import system. (+info)Association of a missense change in the D2 dopamine receptor with myoclonus dystonia. (3/432)
Hereditary autosomal dominant myoclonus dystonia (MD) is a movement disorder characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Although various large families with MD have been described, no positive linkage has been found to a chromosomal location. We report a family with eight members with MD. Linkage analysis identified a 23-centimorgan region on chromosome 11q23 that cosegregates with the disease state (maximum multipoint logarithm of odds score = 2.96 at D11S897). This region contains an excellent candidate gene for involvement in the etiology of MD, the D2 dopamine receptor (DRD2) gene. Neurotransmission mediated by DRD2 is known to have a key role in the control of movement and also has been implicated in reward and reinforcement mechanisms and psychiatric disorders. Sequencing of the coding region of DRD2 indicated that all affected and obligate carriers were heterozygous for a Val154Ile change in exon 3 of the protein, which is highly conserved across species. This change was found neither in other unaffected members of the pedigree nor in 250 control chromosomes. Our finding provides evidence for the involvement of DRD2 in a disorder of the central nervous system and should lead to further insight into the function of the dopaminergic system in dystonia and other movement and mood disorders. (+info)From off-period dystonia to peak-dose chorea. The clinical spectrum of varying subthalamic nucleus activity. (4/432)
The effect of chronic bilateral high-frequency stimulation of the subthalamic nucleus (STN) on levodopa-induced dyskinaesias was investigated in eight patients with fluctuating Parkinson's disease complicated by functionally disabling off-period dystonia. All of the patients also had severe diphasic and peak-dose chorea, so that it was possible to study the effect of high-frequency stimulation on the different types of levodopa-induced dyskinaesias. Off-period fixed dystonia was reduced by 90% and off-period pain by 66%. After acute levodopa challenge, high-frequency stimulation of the STN reduced diphasic mobile dystonia by 50% and peak-dose choreic dyskinaesias by 30%. The effect of bilateral high-frequency stimulation of the STN on the Unified Parkinson's Disease Rating Scale motor score had the same magnitude as the preoperative effect of levodopa. This allowed the levodopa dose to be reduced by 47%. The combination of reduced medication and continuous high-frequency stimulation of the STN reduced the duration of on-period diphasic and peak-dose dyskinaesias by 52% and the intensity by 68%. Acute high-frequency stimulation of the STN mimics an acute levodopa challenge, concerning both parkinsonism and dyskinaesias, and suppresses off-period dystonia. Increasing the voltage can induce repetitive dystonic dyskinaesias, mimicking diphasic levodopa-induced dyskinaesias. A further increase in voltage leads to a shift from a diphasic-pattern dystonia to a peak-dose pattern choreodystonia. Chronic high-frequency stimulation of the STN also mimics the benefit of levodopa on parkinsonism and improves all kinds of levodopa-induced dyskinaesias to varying degrees. Off-period dystonia, associated with neuronal hyperactivity in the STN is directly affected by stimulation and disappears immediately. The effect of chronic high-frequency stimulation of the STN on diphasic and peak-dose dyskinaesias is more complex and is related directly to the functional inhibition of the STN and indirectly to the replacement of the pulsatile dopaminergic stimulation by continuous functional inhibition of the STN. Chronic high-frequency stimulation of the STN allows a very gradual increase in stimulation parameters with increasing beneficial effect on parkinsonism while reducing the threshold for the elicitation of stimulation-induced dyskinaesias. In parallel with improvement of parkinsonism, the levodopa dose can be gradually decreased. As diphasic dystonic dyskinaesias are improved to a greater degree than peak-dose dyskinaesias, both direct and indirect mechanisms may be involved. Peak-dose choreatic dyskinaesias, associated with little evidence of parkinsonism and thus with low neuronal activity in the STN, are improved, mostly indirectly. Fixed off-period dystonia, mobile diphasic dystonia and peak-dose choreodystonia seem to represent a continuous clinical spectrum reflecting a continuous spectrum of underlying activity patterns of STN neurons. (+info)Generalised muscular weakness after botulinum toxin injections for dystonia: a report of three cases. (5/432)
Three patients are reported on who developed transient generalised weakness after receiving therapeutic doses of botulinum toxin for cervical dystonia (one case) and symptomatic hemidystonia (two cases) respectively. Clinical and electrophysiological findings were in keeping with mild botulism. All patients had received previous botulinum toxin injections without side effects and one patient continued injections without recurrence of generalised weakness. The cause is most likely presynaptic inhibition due to systemic spread of the toxin. Patients with symptomatic dystonia may be more likely to have this side effect and botulinum toxin injections in these patients should be carried out cautiously. (+info)Clinical genetics of familial progressive supranuclear palsy. (6/432)
Recent studies have shown that progressive supranuclear palsy (PSP) could be inherited, but the pattern of inheritance and the spectrum of the clinical findings in relatives are unknown. We here report 12 pedigrees, confirmed by pathology in four probands, with familial PSP. Pathological diagnosis was confirmed according to recently reported internationally agreed criteria. The spectrum of the clinical phenotypes in these families was variable including 34 typical cases of PSP (12 probands plus 22 secondary cases), three patients with postural tremor, three with dementia, one with parkinsonism, two with tremor, dystonia, gaze palsy and tics, and one with gait disturbance. The presence of affected members in at least two generations in eight of the families and the absence of consanguinity suggests autosomal dominant transmission with incomplete penetrance. We conclude that hereditary PSP is more frequent than previously thought and that the scarcity of familial cases may be related to a lack of recognition of the variable phenotypic expression of the disease. (+info)Abnormal cortical processing of voluntary muscle relaxation in patients with focal hand dystonia studied by movement-related potentials. (7/432)
In order to clarify the abnormality in cortical motor preparation for voluntary muscle relaxation of the hand in patients with focal hand dystonia, Bereitschaftspotentials (BPs) preceding voluntary muscle contraction and relaxation were recorded in eight patients (three with simple writer's cramp and five with dystonic writer's cramp), and were compared with those from 10 normal subjects. Voluntary muscle relaxation: after keeping the right wrist in an extended position for > 5 s, the subject let the hand drop by voluntarily terminating muscle contraction of the wrist extensor without any associated muscle contraction. Voluntary muscle contraction: the right wrist was flexed by voluntarily contracting the wrist flexor muscle. Scalp EEGs were recorded from 11 electrodes placed over the frontal, central and parietal areas. In the control group, the BP measured at the movement onset was maximal at the left central area (C1), and distributed predominantly over the left hemisphere equally in both the contraction and relaxation tasks. In the focal hand dystonia group, BP was maximal at C1 in the contraction task, whereas, in the relaxation task, it was maximal at the midline central area (Cz) and symmetrically distributed. At the left central area, the BP amplitude in the focal hand dystonia group was diminished significantly in the relaxation task compared with the contraction task (P < 0.05). The present results demonstrate for the first time that the cortical preparatory process for voluntary muscle relaxation, or motor inhibition, is abnormal in focal hand dystonia. (+info)Risk factors for spread of primary adult onset blepharospasm: a multicentre investigation of the Italian movement disorders study group. (8/432)
OBJECTIVES: Little is known about factors influencing the spread of blepharospasm to other body parts. An investigation was carried out to deterrmine whether demographic features (sex, age at blepharospasm onset), putative risk, or protective factors for blepharospasm (family history of dystonia or tremor, previous head or face trauma with loss of consciousness, ocular diseases, and cigarette smoking), age related diseases (diabetes, hypertension), edentulousness, and neck or trunk trauma preceding the onset of blepharospasm could distinguish patients with blepharospasm who had spread of dystonia from those who did not. METHODS: 159 outpatients presenting initially with blepharospasm were selected in 16 Italian Institutions. There were 104 patients with focal blepharospasm (mean duration of disease 5.3 (SD 1.9) years) and 55 patients in whom segmental or multifocal dystonia developed (mainly in the cranial cervical area) 1.5 (1.2) years after the onset of blepharospasm. Information was obtained from a standardised questionnaire administered by medical interviewers. A Cox regression model was used to examine the relation between the investigated variables and spread. RESULTS: Previous head or face trauma with loss of consciousness, age at the onset of blepharospasm, and female sex were independently associated with an increased risk of spread. A significant association was not found between spread of dystonia and previous ocular diseases, hypertension, diabetes, neck or trunk trauma, edentulousness, cigarette smoking, and family history of dystonia or tremor. An unsatisfactory study power negatively influenced the validity and accuracy of the negative findings relative to diabetes, neck or trunk trauma, and cigarette smoking. CONCLUSIONS: The results of this exploratory study confirm that patients presenting initially with blepharospasm are most likely to experience some spread of dystonia within a few years of the onset of blepharospasm and suggest that head or face trauma with loss of consciousness preceding the onset, age at onset, and female sex may be relevant to spread. The suggested association between edentulousness and cranial cervical dystonia may be apparent because of the confounding effect of both age at onset and head or face trauma with loss of consciousness. The lack of influence of family history of dystonia on spread is consistent with previous findings indicating that the inheritance pattern is the same for focal and segmental blepharospasm. (+info)
Acute dystonic reaction legal definition of acute dystonic reaction
Isolated focal dystonia | Neurology
Symptoms and Diagnosis | Dystonia Medical Research Foundation Canada
Acute Dystonic Reaction: Overview
Deep brain stimulation for dystonia. - Department of Physiology, Anatomy and Genetics (DPAG)
Deep brain stimulation for dystonia. - Oxford Neuroscience
Rapid Onset Dystonia Parkinsonism | Dystonia Medical Research Foundation
Best Limb Dystonia Doctor in Navi Mumbai, Limb Dystonia Doctors | Credihealth
Thalamic post-inhibitory bursting occurs in patients with organic dystonia more often than controls<...
Chronic stimulation of the globus pallidus internus for treatment of non-DYT1 generalized dystonia and choreoathetosis: 2-year...
Acute Dystonic Reaction: Warning Signs
What is Dystonia? | Dystonia Medical Research Foundation Canada
acute dystonic reaction
X-Linked Dystonia-Parkinsonism (Lubag) - Dystonia Ireland
2019 Summer - Dystonia Europe
Deep brain stimulation for treatment of dystonia secondary to stroke or trauma | Journal of Neurology, Neurosurgery & Psychiatry
The prognosis of fixed dystonia: a follow-up study.
X-linked Dystonia Parkinsonism | Dystonia Medical Research Foundation
Dystonia in parkinsons disease Clinical and pharmacological features.
Primary dystonia: Moribund or viable. | Foundation Dystonia Research
Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype...
How is Parkinsons Disease Related to Dystonia? | Bachmann Strauss Dystonia & Parkinson Foundation, Inc.
Top Limb Dystonia Hospitals in Delhi NCR | Credihealth
Somatosensory Processing in Focal Hand Dystonia - Full Text View - ClinicalTrials.gov
Tardive and idiopathic oromandibular dystonia: a clinical comparison | Journal of Neurology, Neurosurgery & Psychiatry
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia - Full Text View - ClinicalTrials.gov
Dystonia, facial dysmorphism, intellectual disability and breast cancer associated with a chromosome 13q34 duplication and...
Living with Embouchure Dystonia: A Short Guide to Key Transposition on French Horn by Katie A. Berglof
Mutations in GNAL: A Novel Cause of Craniocervical Dystonia. | Foundation Dystonia Research
Poststreptococcal dystonia with bilateral striatal enlargement: MR imaging and spectroscopic findings<...
Dystonia Health Advocate - Blog
Most recent papers with the keyword Dyskinetic cerebral palsy and dystonia | Read by QxMD
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What is Oromandibular Dystonia? - Point Click Cares
Dystonia and Chronic Pain
Gene Mutations Identified As Cause of Primary Torsion Dystonia - The Mount Sinai Hospital
Dystonia Disorder -Birth Injury Support
Dystonia and Social Security Disability | Disability Benefits Center
Myoclonus Dystonia
Dystonia and Disability Benefits<...
Cervical Dystonia Market Sparkling Growth Rate by Worldwide Trending Players and 5% of CAGR by 2023 | Kansasnews Headlines
Focal Hand Dystonia | Musculoskeletal Key
Dystonic Disorders; Familial Dystonia; Focal Dystonia; Pseudodystonia; Writers Cramp
UAB - School of Medicine - Neurology - Gift will fund dystonia research at UAB
Motor and non-motor symptoms in cervical dystonia: a serotonergic perspective</em>...
Psychiatric co-morbidity is highly prevalent in idiopathic cervical dystonia and significantly influences health-related...
Cervical Dystonia - NORD (National Organization for Rare Disorders)
Determinants of disability in cervical dystonia<...
Sensory motor retuning : a behavioral treatment for focal hand dystonia of pianists and guitarists
Long-Term Abobotulinumtoxin A Treatment of Cervical Dystonia<...
New Hope For Dystonia Treatment Through Deep Brain Stimulation ( Dystonia a group of diseases that caus...)
Repositorio da Producao Cientifica e Intelectual da Unicamp: The Dystonia - Tardive Dyskinesia Syndrome: Case Report And...
Laryngeal Dystonia (Spasmodic Dysphonia) | St Vincents ENT
Dystonia Advocacy Network - National Spasmodic Torticollis Association - NSTA
Torsion dystonia - Wikipedia
Cervical Dystonia - Jeunesse Medical Aesthetics & Laser
Oromandibular Dystonia & Communication | dystonia and me
Cervical dystonia :: causes, symptoms, complications, treatment & medicines of cervical dystonia - MedicScientist :: Total...
Cervical dystonia Market Research Report- Global Forecast To 2023 | MRFR
Global cervical dystonia Market categorizes the Global Market by Type, Treatment and end-user, cervical dystonia Industry ... cervical dystonia market is growing at a CAGR of 5 % during forecasted period 2017-2023, ... Figure 1- Global cervical dystonia market share, by region. Market Scenario:. Cervical dystonia is a rare disease also known as ... 7. GLOBAL CERVICAL DYSTONIA MARKET, BY END USER. 7.1 HOSPITAL. 7.2 CLINICS 7.3 OTHER. 8. GLOBAL CERVICAL DYSTONIA MARKET, BY ...
Focal dystonia - Wikipedia
Focal dystonia is a neurological condition, a type of dystonia, that affects a muscle or group of muscles in a specific part of ... In musicians, the condition is called musicians focal dystonia, or simply, musicians dystonia. In sports, it may be involved ... Understanding musicians Focal dystonia". Galene Editions 2004.. *. Leisner, David (2007). "Curing Focal Dystonia or How to ... Dystonia. The Canadian Movement Disorder group. http://cmdg.org/Dystonia/dystonia.htm ...
Dystonia | MedlinePlus
Dystonia is a movement disorder. It causes involuntary, often painful, contractions of your muscles. Learn about causes, ... Dystonia: Emotional and Mental Health (Dystonia Medical Research Foundation) * Dystonia: Physical Therapy (Dystonia Medical ... Dystonias (National Institute of Neurological Disorders and Stroke) - Short Summary * Dystonias (National Institute of ... Dystonia 6: MedlinePlus Genetics (National Library of Medicine) * Early-onset primary dystonia: MedlinePlus Genetics (National ...
Dystonia
... is a neurological movement disorder, which is characterised by spasms and sustained contractions of the muscles. Find ... Focal dystonias. Neck dystonia or cervical dystonia. Neck dystonia or sometimes known as spasmodic torticollis, is the ... Generalised dystonia is more severe and can affect the entire body.. Primary dystonia refers to the situation where dystonia is ... Voice dystonia or laryngeal dystonia. Voice dystonia or sometimes called spasmodic dysphonia is a voice disorder caused by ...
What is focal dystonia?
Focal dystonia, or the yips, is a neurologic disorder featuring involuntary movements or spasms of small muscles. It can ... www.dystonia.org.uk/index.php/about-dystonia/types-of-dystonia/focal-hand-dystonia/musicians-dystonia-musicians-cramp. ... www.dystonia.org.uk/index.php/about-dystonia/types-of-dystonia/focal-hand-dystonia/musicians-dystonia-musicians-cramp ... The Dystonia Society. (2011). Causes of dystonia. Retrieved from The Dystonia Society. (2012, January). Musicians dystonia. ...
Dystonia 16: MedlinePlus Genetics
Dystonia 16 is one of many forms of dystonia, which is a group of conditions characterized by involuntary movements, twisting ( ... Dystonias are estimated to affect 250,000 people in the United States. Dystonia 16 is a rare form of dystonia; its prevalence ... Dystonia 16 is one of many forms of dystonia, which is a group of conditions characterized by involuntary movements, twisting ( ... laryngeal dystonia), resulting in a quiet, breathy voice or an inability to speak clearly. Dystonia 16 gradually gets worse, ...
Dystonia: Symptoms, causes, and types
Dystonia is characterized by involuntary movements and extended muscle contractions. Here, learn about the symptoms and the ... Dystonia refers to a range of movement disorders that affect the brain and nerves, but not cognitive abilities such as memory. ... Some types of dystonia are linked to faulty genes.. Causes of secondary dystonia. This type of dystonia is caused by a ... Drug induced dystonia. Certain drugs can cause dystonia. Cases of drug-induced dystonia normally occur after just one exposure ...
DYSTONIA BAFFLES DOCTORS - Sun Sentinel
I would appreciate anything you could tell me about dystonia and its treatment. - M.S. Dear M.S.: Dystonia - an involuntary ... Donohue: My wife was diagnosed as having dystonia. ... Dear M.S.: Dystonia - an involuntary contraction of one or more ... With localized dystonia, injections of Botox often works.. Have your wife call the Dystonia Medical Research Foundation at 800- ... Donohue: My wife was diagnosed as having dystonia. I would appreciate anything you could tell me about dystonia and its ...
Unawareness of dystonia. | The BMJ
Genetics in dystonia. - PubMed - NCBI
While Hermann Oppenheim probably described the first cases of genetic (DYT1) dystonia in 1911, the modern history of dystonia ... Confirmed genes for isolated dystonias include TOR1A/DYT1; THAP1/DYT6; GNAL/DYT25. In the combined forms, dystonia is ... Genetics in dystonia.. Klein C1.. Author information. 1. Institute of Neurogenetics, University of Lübeck, Lübeck, Germany. ... Due to the advent of next-generation sequencing, the field of dystonia genetics has been evolving very rapidly over the past ...
Segmental dystonia | pathology | Britannica.com
What Causes Dystonia?
Dystonia is thought to be neurological in origin, but the condition does not affect peoples intelligence, memory or language ... Dystonias are disorders characterized by muscle spasms and contractions. ... If the dystonia is genetic or the cause is unknown, it is termed primary dystonia, while dystonia that occurs due to an ... Secondary dystonia. Also known as acquired dystonia, secondary dystonias are usually caused by another condition, some of which ...
Dystonia | Abbott U.S.
AANS | Dystonia
Learn about different classifications of dystonia, as well as common symptoms and treatment options. Get a complete overview of ... Dystonia Classification by Body Part. Focal Dystonia. Focal dystonia is limited to one area of the body and can affect the neck ... Dystonia-plus syndromes include dopa-responsive dystonia (DRD) or Segawa syndrome, rapid-onset dystonia-parkinsonism (RDP) and ... laryngeal dystonia) or arms/legs (limb dystonia). Other less common types of focal dystonias can cause unusual stretching, ...
Dystonia - Wikipedia
... hand dystonia, blepharospasm, oromandibular dystonia, dysphonia and musicians dystonia. Some focal dystonias have been proven ... There are multiple types of dystonia, and many diseases and conditions may cause dystonia. Dystonia is classified by: Clinical ... Primary dystonia is suspected when the dystonia is the only sign and there is no identifiable cause or structural abnormality ... Cerebellum issues causing dystonia is described by Filip et al. 2013: "Although dystonia has traditionally been regarded as a ...
Myoclonic dystonia (Concept Id: C1834570)
- MedGen - NCBI
Approximately 50% of affected individuals have additional focal or segmental dystonia, presenting as cervical dystonia and/or ... dystonia). The myoclonic jerks typical of M-D most often affect the neck, trunk, and upper limbs with less common involvement ... Myoclonus-dystonia (M-D) is a movement disorder characterized by a combination of rapid, brief muscle contractions (myoclonus) ... Dystonia 11; DYSTONIA 11, MYOCLONIC; Dystonia, alcohol responsive; DYT11; Hereditary essential myoclonus; Myoclonus-Dystonia; ...
Dystonia | Rush System
Rush movement disorder experts tailor dystonia treatments (e.g., botulinum toxin injections or deep brain stimulation) to ... Types of Dystonia. Dystonia can affect only a specific group of muscles or many groups. Dystonia is classified by the group of ... Ongoing dystonia research and expertise: The Dystonia Study Group, a national group of dystonia experts, is led by movement ... Dystonia Symptoms. Early signs of dystonia can be subtle and include the following:. *Trembling of limbs, hands and face ( ...
Dystonia | Parkinson's Disease
There are two main categories of dystonia: primary and secondary.. In primary dystonia, dystonia is the only clinical feature. ... Dystonia. Dystonia can be a symptom of Parkinsons and some other diseases and is a movement disorder on its own. Painful, ... Types of Dystonia. Dystonia is the third most common movement disorder, affecting an estimated 500,000 adults and children in ... In secondary dystonia, other symptoms are also present. Some other forms of dystonia also have parkinsonism, a term used to ...
What is Dystonia?
Botox & Dystonia | DailyStrength
I had hoped that after my DBS surgery seven months ago that I would no longer suffer from the pain brought on by dystonia in my ... I had hoped that after my DBS surgery seven months ago that I would no longer suffer from the pain brought on by dystonia in my ... But he does have Dystonia in his feet. When the problem first started in 2005 we went through 3 months of pure hell. It was ... I would like to hear your stories, either positive or negatative, as it relates to treating feet dystonia with Botox injections ...
Dystonia - Trip Database
Helping you find trustworthy answers on Dystonia , Latest evidence made easy ... Find all the evidence you need on Dystonia via the Trip Database. ... Unmet Needs in Dystonia: Genetics and Molecular Biologyâ€"How Many Dystonias? (PubMed). Unmet Needs in Dystonia: Genetics and ... 1. Dystonias Dystonias Dystonias - Symptoms, diagnosis and treatment , BMJ Best Practice Youll need a subscription to access ...
Dystonia - Trip Database
Helping you find trustworthy answers on Dystonia , Latest evidence made easy ... Find all the evidence you need on Dystonia via the Trip Database. ... X-linked dystonia-parkinsonism is a neurodegenerative movement disorder characterized by adult-onset dystonia combined with ... Youngest presenting patient with dystonia 24 and review of the literature (PubMed). Youngest presenting patient with dystonia ...
Dystonia - definition of dystonia by The Free Dictionary
dystonia synonyms, dystonia pronunciation, dystonia translation, English dictionary definition of dystonia. n. Abnormal ... com)-- The Dystonia Medical Foundation (DMRF) is proud to cheer on Dystance4Dystonia runner Carrie Siu Butt in her fifth and ... Clozapine and botulinum toxin have proven efficacy against tardive dystonia, said Dr.. Tx options help relieve tardive dystonia ... from dys- + -tonia from Greek tonos tension, from teinen to stretch]. dys•to•ni•a. (dɪsˈtoʊ ni ə) n. a neurological disorder ...
Acute dystonia induced by drug treatment | The BMJ
Risk factors for acute, drug induced dystonia include young age, male sex, use of cocaine, and a history of acute dystonia ... Acute dystonia induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs, and it may ... Drug induced dystonia can be prevented either by adding, during the first four to seven days of treatment, anticholinergic ... Acute dystonia caused by drug treatment can seriously disturb the relationship between doctor and patient and should be ...
Ambien, GABA and Dystonia - Neurology - MedHelp
I was diagnosed with Focal Dystonia in my wrist a few months ago. Since then it has become multifocal, affecting both feet and ... Ambien, GABA and Dystonia. I was diagnosed with Focal Dystonia in my wrist a few months ago. Since then it has become ... I have Dystonia also and was prescribed Ambien. I feel great in the morning when I wake up. I dissapeares after an hour or so ... I have Dystonia also and was prescribed Ambien. I feel great in the morning when I wake up. I dissapeares after an hour or so ...
Dopamine-Responsive Dystonia: Background, Etiology, Epidemiology
... also known as dopa-responsive dystonia or as hereditary progressive dystonia with diurnal variation (HPD), is an inherited ... dystonia typically presenting in the first decade of life (although it may present in the second to early third decades, or ... Dopamine-responsive dystonia (DRD), also known as dopa-responsive dystonia or as hereditary progressive dystonia with diurnal ... encoded search term (Dopamine-Responsive Dystonia) and Dopamine-Responsive Dystonia What to Read Next on Medscape ...
Cervical Dystonia : Neurology Now
My wife first exhibited cervical dystonia symptoms in about 1984, although it would be another five years before a diagnosis ... Your article on cervical dystonia overlooked the very important treatment option of selective denervation. ... she shows few residual signs of cervical dystonia. Although not totally pain free, she has enjoyed life to an extent that would ...
What Is Dystonia? What Causes Dystonia? - Care2 News Network
Dystonia is a general term which describes involuntary movements and extended muscle contractions - a range of movement ... What Is Dystonia? What Causes Dystonia?. Health & Wellness (tags: dystonia, movement disorders, neurological illness, ... I have Generalized Dystonia myself & my Dystonia also affects my speech!!! I got Botox injections which does help my tremors ... Dystonia is a general term which describes involuntary movements and extended muscle contractions - a range of movement ...