Ductus arteriosus. Medical search

A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth.

A fetal blood vessel connecting the pulmonary artery with the descending aorta.

A congenital anomaly caused by the failed development of TRUNCUS ARTERIOSUS into separate AORTA and PULMONARY ARTERY. It is characterized by a single arterial trunk that forms the outlet for both HEART VENTRICLES and gives rise to the systemic, pulmonary, and coronary arteries. It is always accompanied by a ventricular septal defect.

An infant during the first month after birth.

A human infant born before 37 weeks of GESTATION.

A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.

The arterial trunk arising from the fetal heart. During development, it divides into AORTA and the PULMONARY ARTERY.

A CATHETER-delivered implant used for closing abnormal holes in the cardiovascular system, especially HEART SEPTAL DEFECTS; or passageways intentionally made during cardiovascular surgical procedures.

The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.

Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.

A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Heart sounds caused by vibrations resulting from the flow of blood through the heart. Heart murmurs can be examined by HEART AUSCULTATION, and analyzed by their intensity (6 grades), duration, timing (systolic, diastolic, or continuous), location, transmission, and quality (musical, vibratory, blowing, etc).

Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Inflammation of the inner endothelial lining (TUNICA INTIMA) of an artery.

Application of a ligature to tie a vessel or strangulate a part.

The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.

Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.

Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.

Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.

The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.

An infant whose weight at birth is less than 1500 grams (3.3 lbs), regardless of gestational age.

Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.

The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.

Use of a balloon CATHETER to block the flow of blood through an artery or vein.

The circulation of the BLOOD through the LUNGS.

A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.

Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.

A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.

Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.

The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.

A species of baboon in the family CERCOPITHECIDAE, often used as an animal model for cognitive studies.

Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.

The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.

An infant whose weight at birth is less than 1000 grams (2.2 lbs), regardless of GESTATIONAL AGE.

Surgery performed on the heart or blood vessels.

Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.

Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.

A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.

A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).

Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.

A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.

A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.

Congenital structural abnormalities of the LOWER EXTREMITY.

A potent vasodilator agent that increases peripheral blood flow.

Surgery performed on the heart.

A condition associated with VENTRICULAR SEPTAL DEFECT and other congenital heart defects that allow the mixing of pulmonary and systemic circulation, increase blood flow into the lung, and subsequent responses to low oxygen in blood. This complex is characterized by progressive PULMONARY HYPERTENSION; HYPERTROPHY of the RIGHT VENTRICLE; CYANOSIS; and ERYTHROCYTOSIS.

Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.

Refers to animals in the period of time just after birth.

Hospital units providing continuing surveillance and care to acutely ill newborn infants.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

ENTEROCOLITIS with extensive ulceration (ULCER) and NECROSIS. It is observed primarily in LOW BIRTH WEIGHT INFANT.

Traumatic injuries to the RECURRENT LARYNGEAL NERVE that may result in vocal cord dysfunction.

Radiography of the heart and great vessels after injection of a contrast medium.

The pathologic narrowing of the orifice of the PULMONARY VALVE. This lesion restricts blood outflow from the RIGHT VENTRICLE to the PULMONARY ARTERY. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.

A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.

An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.

Any drug treatment modality designed to inhibit UTERINE CONTRACTION. It is used in pregnant women to arrest PREMATURE LABOR.

An assessment of a person's personality based on their facial and other external features.

This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.

A congenital heart defect characterized by the narrowing or complete absence of the opening between the RIGHT VENTRICLE and the PULMONARY ARTERY. Lacking a normal PULMONARY VALVE, unoxygenated blood in the right ventricle can not be effectively pumped into the lung for oxygenation. Clinical features include rapid breathing, CYANOSIS, right ventricle atrophy, and abnormal heart sounds (HEART MURMURS).

Abnormalities in any part of the HEART SEPTUM resulting in abnormal communication between the left and the right chambers of the heart. The abnormal blood flow inside the heart may be caused by defects in the ATRIAL SEPTUM, the VENTRICULAR SEPTUM, or both.

Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.

Radiography of blood vessels after injection of a contrast medium.

Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.

An infant having a birth weight of 2500 gm. (5.5 lb.) or less but INFANT, VERY LOW BIRTH WEIGHT is available for infants having a birth weight of 1500 grams (3.3 lb.) or less.

A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

The main trunk of the systemic arteries.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.

A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.

A valve situated at the entrance to the pulmonary trunk from the right ventricle.

The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.

The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.

Methods of creating machines and devices.

Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.

A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.

Congenital structural abnormalities of the UPPER EXTREMITY.

Surgical incision into the chest wall.

A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).

Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.

Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.

A congenital heart defect characterized by downward or apical displacement of the TRICUSPID VALVE, usually with the septal and posterior leaflets being attached to the wall of the RIGHT VENTRICLE. It is characterized by a huge RIGHT ATRIUM and a small and less effective right ventricle.

Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)

The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.

Prenatal features of ductus arteriosus constriction and restrictive foramen ovale in d-transposition of the great arteries. (1/253)

BACKGROUND: Although most neonates with d-transposition of the great arteries (TGA) have an uncomplicated preoperative course, some with a restrictive foramen ovale (FO), ductus arteriosus (DA) constriction, or pulmonary hypertension may be severely hypoxemic and even die shortly after birth. Our goal was to determine whether prenatal echocardiography can identify these high-risk fetuses with TGA. METHODS AND RESULTS: We reviewed the prenatal and postnatal echocardiograms and outcomes of 16 fetuses with TGA/intact ventricular septum or small ventricular septal defect. Of the 16 fetuses, 6 prenatally had an abnormal FO (fixed position, flat, and/or redundant septum primum). Five of the 6 had restrictive FO at birth. Five fetuses had DA narrowing at the pulmonary artery end in utero, and 6 had a small DA (diameter z score of <-2.0). Of 4 fetuses with the most diminutive DA, 2 also had an abnormal appearance of the FO, and both died immediately after birth. One other fetus had persistent pulmonary hypertension. Eight fetuses had abnormal Doppler flow pattern in the DA (continuous high-velocity flow, n=1; retrograde diastolic flow, n=7). CONCLUSIONS: Abnormal features of the FO, DA, or both are present in fetuses with TGA at high risk for postnatal hypoxemia. These features may result from the abnormal intrauterine hemodynamics in TGA. A combination of restrictive FO and DA constriction in TGA may be associated with early neonatal death. (+info)

Inducible NO synthase inhibition attenuates shear stress-induced pulmonary vasodilation in the ovine fetus. (2/253)

Recent studies have suggested that type II (inducible) nitric oxide (NO) synthase (NOS II) is present in the fetal lung, but its physiological roles are uncertain. Whether NOS II activity contributes to the NO-mediated fall in pulmonary vascular resistance (PVR) during shear stress-induced pulmonary vasodilation is unknown. We studied the hemodynamic effects of two selective NOS II antagonists [aminoguanidine (AG) and S-ethylisothiourea (EIT)], a nonselective NOS antagonist [nitro-L-arginine (L-NNA)], and a nonselective vasoconstrictor (U-46619) on PVR during partial compression of the ductus arteriosus (DA) in 20 chronically prepared fetal lambs (mean age 132 +/- 2 days, term 147 days). At surgery, catheters were placed in the left pulmonary artery (LPA) for selective drug infusion, an ultrasonic flow transducer was placed on the LPA to measure blood flow, and an inflatable vascular occluder was placed loosely around the DA for compression. On alternate days, a brief intrapulmonary infusion of normal saline (control), AG, EIT, L-NNA, or U-46619 was infused in random order into the LPA. The DA was compressed to increase mean pulmonary arterial pressure (MPAP) 12-15 mmHg above baseline values and held constant for 30 min. In control studies, DA compression reduced PVR by 42% from baseline values (P < 0.01). L-NNA treatment completely blocked the fall in PVR during DA compression. AG and EIT attenuated the decrease in PVR by 30 and 19%, respectively (P < 0.05). Nonspecific elevation in PVR by U-46619 did not affect the fall in PVR during DA compression. Immunostaining for NOS II identified this isoform in airway epithelium and vascular smooth muscle in the late-gestation ovine fetal lung. We conclude that selective NOS II antagonists attenuate but do not block shear stress-induced vasodilation in the fetal lung. We speculate that stimulation of NOS II activity, perhaps from smooth muscle cells, contributes in part to the NO-mediated fall in PVR during shear stress-induced pulmonary vasodilation. (+info)

Cyclooxygenase-2 plays a significant role in regulating the tone of the fetal lamb ductus arteriosus. (3/253)

Nonselective cyclooxygenase (COX) inhibitors are potent tocolytic agents but have adverse effects on the fetal ductus arteriosus. We hypothesized that COX-2 inhibitors may not affect the ductus if the predominant COX isoform is COX-1. To examine this hypothesis, we used ductus arteriosus obtained from late-gestation fetal lambs. In contrast to our hypothesis, fetal lamb ductus arteriosus expressed both COX-1- and COX-2-immunoreactive protein (by Western analysis). Although COX-1 was found in both endothelial and smooth muscle cells, COX-2 was found only in the endothelial cells lining the ductus lumen (by immunohistochemistry). The relative contribution of COX-1 and COX-2 to PGE2 synthesis was consistent with the immunohistochemical results: in the intact ductus, PGE2 formation was catalyzed by both COX-1 and COX-2 in equivalent proportions; in the endothelium-denuded ductus, COX-2 no longer played a significant role in PGE2 synthesis. NS-398, a selective inhibitor of COX-2, was 66% as effective as the selective COX-1 inhibitor valeryl salicylate and the nonselective COX inhibitor indomethacin in causing contraction of the ductus in vitro. At this time, caution should be used when recommending COX-2 inhibitors for use in pregnant women. (+info)

The effects of maternal indomethacin therapy on human fetal branch pulmonary arterial vascular impedance. (4/253)

OBJECTIVE: To examine whether maternal indomethacin therapy affects human fetal pulmonary arterial vascular impedance without constriction of the ductus arteriosus and to determine the changes in the pulmonary arterial vascular impedance in the presence of ductal constriction. STUDY DESIGN: In this cross-sectional study, 52 normal fetuses without maternal medication (control group), 33 fetuses without ductal constriction (Study group I) and 11 fetuses with ductal constriction (Study group II) during maternal indomethacin therapy between 24 and 34 weeks of gestation were examined by Doppler echo-cardiography. Blood velocity waveforms across the proximal right or left pulmonary artery were obtained and the pulsatility index (PI) of the proximal pulmonary arteries was calculated. RESULTS: In the control group, the proximal pulmonary artery PI was higher (p < 0.0001) at 24-25 weeks (n = 7) (3.73 +/- 0.33; mean +/- SD) than at 33-34 week of gestation (n = 11) (2.98 +/- 0.27). The PI was constantly greater (p < 0.005) in Study group I than in the control group. However, in this group the mean average weekly decrease in the PI of the proximal pulmonary arteries was similar to that in the control group. After 26 weeks of gestation, the PI values in Study group II were significantly higher than in the control group (27 weeks: 4.12 vs. 3.34 (p < 0.005); 30 weeks: 4.48 vs. 3.14 (p < 0.0001); 34 weeks: 4.96 vs. 3.00 (p < 0.0001), respectively). CONCLUSIONS: Human fetal pulmonary arterial vascular impedance is increased by maternal indomethacin therapy even without ductal constriction. In the presence of ductal constriction, the magnitude of the increase in the vascular impedance is related to the gestational age. (+info)

Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle. (5/253)

OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II & III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 +/- 3.03 ml/m2 and mean Rhodes score of -1.73 +/-0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLVV was 19.4+/-3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38+/-1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high. (+info)

Coanda effect on ductal flow in the pulmonary artery. (6/253)

The Coanda effect (the tendency of a jet stream to adhere to a boundary wall), and the relevant anatomy, may explain the location of ductal jets within the main pulmonary artery. With the usual insertion of the duct close to the left pulmonary artery, during right ventricular ejection, the ductal jet adheres to the left wall of the main pulmonary artery. When right ventricular ejection is absent in pulmonary atresia, the ductal jet streams down the right wall of the pulmonary artery to the pulmonary valve, reverses, and maintains a parallel column back toward the bifurcation. If the reversed flow is mistaken for ejection from the right ventricle, the diagnosis of pulmonary atresia may be missed. (+info)

Fate of the stented arterial duct. (7/253)

BACKGROUND: The technical aspects of ductal stenting have been reported, but little is known of the fate of the duct after stent implantation. METHODS AND RESULTS: Nineteen patients underwent stent implantation to maintain ductal patency. Eight had hypoplastic left heart (HLH) syndrome, 10 had pulmonary atresia, and 1 had tricuspid atresia. Median survival with HLH was 57 (12 to 907) days. Stent implantation was successful in all cases of HLH, but there were no long-term survivors. Two well-palliated infants died at transplantation. Median survival with duct-dependent pulmonary flow was 183 (0 to 1687) days, with 3 patients well at latest follow-up (56, 55, and 9 months, respectively). There were 2 operative deaths due to ductal spasm and 4 late deaths, 1 due to duct thrombosis, 1 due to chronic lung disease, and 2 of unknown cause. Stent implantation failed in 4 of the 11 cases. Assessment of endothelialization was possible in 13 cases; the stent was partially covered in 3 and fully endothelialized in all 10 cases assessed >8 weeks after implantation. In patients stented for inadequate pulmonary flow, ductal intimal hyperplasia occurred by 9 months in all 3 survivors but responded to repeated dilation. CONCLUSIONS: Ductal stenting cannot be recommended. In patients with HLH, it provides only short-term palliation even when combined with pulmonary artery banding. With duct-dependent pulmonary blood flow, the procedure carries high risk, and duration of palliation is poor. In patients with bilateral ducts and absent central pulmonary arteries, good palliation may be achieved, but repeated angioplasty is necessary to counteract intimal hyperplasia. (+info)

Ductus venosus blood velocity in persistent pulmonary hypertension of the newborn. (8/253)

AIMS: To investigate the ductus venosus flow velocity (DVFV) in infants with persistent pulmonary hypertension of the newborn (PPHN); to evaluate the DVFV pattern as a possible diagnostic supplement in neonates with PPHN and other conditions with increased right atrial pressure. METHODS: DVFV was studied in 16 neonates with PPHN on days 1-4 of postnatal life using Doppler echocardiography. DVFV was compared with that in mechanically ventilated neonates with increased intrathoracic pressure, but without signs of PPHN (n=11); with neonates with congenital heart defects resulting in right atrial pressure (n=6); and with preterm neonates without PPHN (n=46); and healthy term neonates (n=50). RESULTS: Infants with PPHN and congenital heart defects with increased right atrial pressure were regularly associated with an increased pulsatile pattern and a reversed flow velocity in ductus venosus during atrial contraction. A few short instances of reversed velocity were also noted in normal neonates before the circulation had settled during the first day after birth. CONCLUSIONS: A reversed velocity in the ductus venosus during atrial contraction at this time signifies that central venous pressure exceeds portal pressure. This negative velocity deflection is easily recognised during Doppler examination and can be recommended for diagnosing increased right atrial pressure and PPHN. (+info)

Failure of the ductus arteriosus to close after birth results in a condition called patent ductus arteriosus, which results in ... The ductus arteriosus, also called the ductus Botalli, named after the Italian physiologist Leonardo Botallo, is a blood vessel ... Upon closure at birth, it becomes the ligamentum arteriosum.[clarification needed] The ductus arteriosus is formed from the ... A patent ductus arteriosus affects approximately 4% of infants with Down syndrome (DS). A failure to thrive is a very common ...

https://en.wikipedia.org/wiki/Ductus_arteriosus

... (PDA) is a medical condition in which the ductus arteriosus fails to close after birth: this allows a ... Patent Ductus Arteriosus Causes from US Department of Health and Human Services Patent Ductus Arteriosus from Merck Patent ... Patent ductus arteriosus (PDA). 22 Dec. 2009 Ohlsson A, Walia R, Shah SS (2015). "Ibuprofen for the treatment of patent ductus ... The ductus arteriosus is a fetal blood vessel that normally closes soon after birth. In a PDA, the vessel does not close, but ...

https://en.wikipedia.org/wiki/Patent_ductus_arteriosus

with D. C. Muir: Muir, D. C.; Brown, J. W. (December 1932). "Patent ductus arteriosus". Arch Dis Child. 7 (42): 291-302. doi: ... with William Whitaker and Donald Heath: Whitaker, W.; Heath, D.; Brown, J. W. (April 1955). "Patent ductus arteriosus with ...

https://en.wikipedia.org/wiki/James_William_Brown

Patent ductus arteriosus . Patent ductus arteriosus (PDA) is an abnormal connection between the aorta and the pulmonary artery ...

https://en.wikipedia.org/wiki/Continuous_murmurs

Patent ductus arteriosus, where blood is channelled back from the heart into the lungs, is also seen and can lead to heart ... "Patent Ductus Arteriosus". American Kennel Club Canine Health Foundation. Archived from the original on 3 July 2011. Retrieved ...

https://en.wikipedia.org/wiki/King_Charles_Spaniel

Borow KM, Hessel SJ, Sloss LJ (1 April 1981). "Fistulous aneurysm of ductus arteriosus". Heart. 45 (4): 467-470. doi:10.1136/ ... "Paralyzed left vocal cord associated with ligation of patent ductus arteriosus". The Journal of Thoracic and Cardiovascular ... Atrial septal defect Aortopulmonary window Ebstein's Anomaly Patent Ductus Arteriosus (PDA) Surgical intervention: ...

https://en.wikipedia.org/wiki/Ortner's_syndrome

If the ductus arteriosus fails to close after birth, a condition known as patent ductus arteriosus can develop. This is a ... The ductus arteriosus becomes the ligamentum arteriosum within three weeks of birth, so that deoxygenated blood can be ... In adults, the ligamentum arteriosum has no useful function. It is a vestige of the ductus arteriosus, a temporary fetal ... Ligamentum teres Ligamentum venosum Pirie, Egle (February 28, 2022). "Ligamentum arteriosum and ductus arteriosus". Kenhub. ...

https://en.wikipedia.org/wiki/Ligamentum_arteriosum

Patent ductus arteriosus is particularly frequent. The majority of such conditions resolve without surgical treatment, although ...

https://en.wikipedia.org/wiki/Pentasomy_X

Burke, Redmond (29 Feb 2008). "Thoracoscopic Approach to Patent Ductus Arteriosus". Operative Techniques in Thoracic and ...

https://en.wikipedia.org/wiki/Redmond_Burke

Campbell, M. (January 1968). "Natural history of persistent ductus arteriosus". Br Heart J. 30 (1): 4-13. doi:10.1136/hrt.30.1. ...

https://en.wikipedia.org/wiki/John_Maurice_Hardman_Campbell

In 1940 he was the first surgeon in Britain to ligate an uninfected patent ductus arteriosus. Fraser, whose parents both came ... Tubbs, Oswald S. (1 July 1944). "The effect of ligation on infection of the patent ductus arteriosus". British Journal of ... ISSN 1365-2168.(subscription required) Gross, Robert; Hubbard, John (1939). "Surgical Ligation of a Patent Ductus Arteriosus". ... 19 October 1940 he became the first surgeon in the British Isles to successfully ligate an uninfected patent ductus arteriosus ...

https://en.wikipedia.org/wiki/Sir_John_Fraser,_1st_Baronet,_of_Tain

October - Robert Edward Gross becomes the first surgeon successfully to ligate an uninfected patent ductus arteriosus, in ... Gross, Robert; Hubbard, John (1939). "Surgical Ligation of a Patent Ductus Arteriosus". Journal of the American Medical ...

https://en.wikipedia.org/wiki/1938_in_science

... and eventual closing of the ductus arteriosus. For an infant with an interrupted aortic arch, a patent (open) ductus arteriosus ... If the diagnosis is made prenatally, prostaglandin E1 (PGE1) is started after birth to avoid closure of the ductus arteriosus. ... While PGE1 is the standard of care for maintaining the ductus arteriosus, there is insufficient data on the proper dose, ... However, the diagnosis may go undetected, delaying treatment until closure of the ductus arteriosus produces symptoms. Curative ...

https://en.wikipedia.org/wiki/Interrupted_aortic_arch

Patent ductus arteriosus also appears in the breed. It is a condition where a small blood vessel connecting two major arteries ...

https://en.wikipedia.org/wiki/Sussex_Spaniel

... helps ductal closure in patent ductus arteriosus. It is as effective for this purpose as ibuprofen or indomethacin ... Ohlsson A, Shah PS (January 2020). "Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight ...

https://en.wikipedia.org/wiki/Paracetamol

As the oxygen-rich blood from the aorta flows across the ductus arteriosus to the pulmonary artery, the ductus arteriosus will ... While oxygen serves as a vasoconstrictor of the ductus arteriosus, prostaglandins can keep the ductus arteriosus open to ... most of the blood flows across the ductus arteriosus away from the lungs. Once the blood goes through the ductus arteriosus, it ... In the fetus, there is a special connection between the pulmonary artery and the aorta, called the ductus arteriosus. Because ...

https://en.wikipedia.org/wiki/Fetal_circulation

Truncus arteriosus (embryology) Patent ductus arteriosus Ruan, Wen; Loh, Yee Jim; Guo, Kenneth Wei Qiang; Tan, Ju Le (2016). " ... Persistent truncus arteriosus (PTA), often referred to simply as truncus arteriosus, is a rare form of congenital heart disease ... arising from a patent ductus arteriosus. Type A4: Common arterial trunk in association with interrupted aortic arch. As both of ... Persistent truncus arteriosus is a rare cardiac abnormality that has a prevalence of less than 1%. Diagrams to illustrate the ...

https://en.wikipedia.org/wiki/Persistent_truncus_arteriosus

Sekar KC, Corff KE (May 2008). "Treatment of patent ductus arteriosus: indomethacin or ibuprofen?". Journal of Perinatology. 28 ... possibly resulting in fetal death via premature closing of the Ductus arteriosus. In October 2020, the U.S. Food and Drug ... with the exception of neonates with patent ductus arteriosus) Severe pre-existing renal and liver damage Caution: pre-existing ... "Idiopathic constriction of the fetal ductus arteriosus: three cases and review of the literature". Journal of Ultrasound in ...

https://en.wikipedia.org/wiki/Indometacin

Patent ductus arteriosus is the most common defect. Septal defects (ventricular septal defects and atrial septal defects) are ...

https://en.wikipedia.org/wiki/Tetrasomy_18p

2008). "Novel TFAP2B mutation in nonsyndromic patent ductus arteriosus". Genet. Test. 12 (3): 457-9. doi:10.1089/gte.2008.0015 ... 2009). "Determination of Genetic Predisposition to Patent Ductus Arteriosus in Preterm Infants". Pediatrics. 123 (4): 1116-23. ...

https://en.wikipedia.org/wiki/TFAP2B

Postductal coarctation: The narrowing is distal to the insertion of the ductus arteriosus. Even with an open ductus arteriosus ... The narrowing occurs at the insertion of the ductus arteriosus. This kind usually appears when the ductus arteriosus closes. ... ductus arteriosus) into an elastic artery (aorta) during fetal life, where the contraction and fibrosis of the ductus ... usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word coarctation means " ...

https://en.wikipedia.org/wiki/Coarctation_of_the_aorta

The ductus arteriosus is a small, artery-like structure which allows blood to flow from the trunk of the pulmonary artery into ... With simple d-TGA, if the foramen ovale and ductus arteriosus are allowed to close naturally, the newborn will likely not ... and patent ductus arteriosus (PDA). Stenosis of valves or vessels may also be present. When no other heart defects are present ... it prevents the ductus arteriosus from closing, therefore providing an additional shunt through which to provide the systemic ...

https://en.wikipedia.org/wiki/Dextro-Transposition_of_the_great_arteries

Treatment is based on: PGE1 to maintain patent ductus arteriosus. First operation: modified Blalock-Taussig shunt to maintain ... connecting the left ventricle to the pulmonary artery or by a patent ductus arteriosus (PDA) connecting the aorta to the ...

https://en.wikipedia.org/wiki/Tricuspid_atresia

It may also be used to close a patent ductus arteriosus in a premature baby. It can be used by mouth or intravenously. It ... It is also used for pericarditis and patent ductus arteriosus. If a patient is self-treating with over-the-counter ibuprofen, ... Rostas SE, McPherson CC (2016). "Pharmacotherapy for Patent Ductus Arteriosus: Current Options and Outstanding Questions". ... for closure of patent ductus arteriosus in premature infants weighing between 500 and 1,500 g (1 and 3 lb), who are no more ...

https://en.wikipedia.org/wiki/Ibuprofen

188 In patent ductus arteriosus, a congenital disorder, the fetal ductus arteriosus fails to close, leaving an open vessel ... MedlinePlus > Patent ductus arteriosus Update Date: 21 December 2009 Seeley, Rod; Stephens, Trent; Philip Tate (1992). "20". In ... A failure of the aorticopulmonary septum to divide the great vessels results in persistent truncus arteriosus. The aorta is an ... which loops under the aortic arch just lateral to the ligamentum arteriosum. It then runs back to the neck. The aortic arch has ...

https://en.wikipedia.org/wiki/Aorta

This is seen in patients with a patent ductus arteriosus. Patients with a large ductus develop progressive pulmonary vascular ... Gillam-Krakauer, Maria; Mahajan, Kunal (2021), "Patent Ductus Arteriosus", StatPearls, Treasure Island (FL): StatPearls ...

https://en.wikipedia.org/wiki/Cyanosis

"Determination of genetic predisposition to patent ductus arteriosus in preterm infants". Pediatrics. 123 (4): 1116-23. doi: ...

https://en.wikipedia.org/wiki/MPGES-2

A small vessel, the ductus arteriosus allows blood from the pulmonary artery to pass to the aorta. The ductus arteriosus stays ... In both conditions, the presence of a patent ductus arteriosus (and, when hypoplasia affects the right side of the heart, a ... Patent ductus arteriosus (PDA) Scimitar syndrome (SS) Partial anomalous pulmonary venous connection (PAPVC) Total anomalous ... Less common defects in the association are truncus arteriosus and transposition of the great arteries.[citation needed] The ...

https://en.wikipedia.org/wiki/Congenital_heart_defect

"Determination of genetic predisposition to patent ductus arteriosus in preterm infants". Pediatrics. 123 (4): 1116-23. doi: ...

https://en.wikipedia.org/wiki/CHD7

Jan SL, Chan SC, Fu YC, Lin SJ (June 2009). "Elastin gene study of infants with isolated congenital ductus arteriosus aneurysm ...

https://en.wikipedia.org/wiki/Elastin

... patent ductus arteriosus and retinopathy of prematurity. There is no statistical evidence that phototherapy causes melanoma. ...

https://en.wikipedia.org/wiki/Biliblanket

... patent ductus arteriosus, tetralogy of Fallot and anomalies of the great vessels. Although pulmonary agenesis, aplasia and ...

https://en.wikipedia.org/wiki/Pulmonary_agenesis

... patent ductus arteriosus Kidneys- polycystic kidney, horseshoe kidney Male genitals- enlarged penis, cryptorchidism Female ...

https://en.wikipedia.org/wiki/Roberts_syndrome

Congenital defects such as a thinned atrial septum, ventricular septal defects, patent ductus arteriosus, dysplastic kidney and ...

https://en.wikipedia.org/wiki/ZTTK_syndrome

Atrial septal defect Ventricular septal defect Patent ductus arteriosus and Coarctation of aorta (may cause cyanosis in some ... Truncus arteriosus (Persistent) Tricuspid atresia Interrupted aortic arch Coarctation of aorta Pulmonary atresia (PA) Pulmonary ...

https://en.wikipedia.org/wiki/List_of_circulatory_system_conditions

... patent ductus arteriosus, and ventricular hypertrophy. Kyphoscoliosis may worsen over time and contribute to these pathologies ...

https://en.wikipedia.org/wiki/Coffin–Lowry_syndrome

... such as a patent ductus arteriosus, referring to the ductus arteriosus which normally becomes ligamentum arteriosum within ...

https://en.wikipedia.org/wiki/Anatomical_terminology

However, the ductus arteriosus closes during the first few days of life, resulting in systemic circulation failure in babies ... In fetal life, this is condition is manageable because the ductus arteriosus acts as a bypass, and supports the delivery of ... placing a stent in the ductus arteriosus to hold it open. This maintains the connection between the aorta and the systemic ...

https://en.wikipedia.org/wiki/Fetal_aortic_stenosis

... prostaglandin will be temporarily used as soon as possible in order to keep the ductus arteriosus open for as long as possible ... since the bodies of babies with pulmonary atresia usually use the ductus arteriosus for lung blood flow pre-natally until birth ... alongside agenesis of the patent ductus arteriosus. Blood flow to the lungs comes from various dysplastic (malformed) blood ... "Prenatal Diagnosis of Pulmonary Atresia With Ventricular Septal Defect and an Aberrant Ductus Arteriosus in a Dextrocardia by ...

https://en.wikipedia.org/wiki/Pulmonary_atresia_with_ventricular_septal_defect

Other features include patent ductus arteriosus, congenital hypertrophy of the left ventricle, and pericardial effusions. ... congenital lipodystrophy The treatment/management for Cantú syndrome is based on surgical option for patent ductus arteriosus ... in ductus). This condition can be diagnosed by genetic testing. Furthermore, an echocardiogram and X-ray may help in the ...

https://en.wikipedia.org/wiki/Cantú_syndrome

Early diagnoses suggest Popal suffers from patent ductus arteriosus, a condition he cannot get treatment for in his native ...

https://en.wikipedia.org/wiki/2004_in_Canada

Cardiac anomalies Neonatal anemia Poor intestinal perfusion Prolonged use of indomethacin for patent ductus arteriosus closure ...

https://en.wikipedia.org/wiki/Necrotizing_enterocolitis

... and reprinted after his death and they introduce the eponymous ductus Botalli which is correctly termed ductus arteriosus. ... foramen Botalli which allows blood in the fetal heart of humans to move from the left to the right atrium and the ductus ...

https://en.wikipedia.org/wiki/Leonardo_Botallo

Initial secretion of bradykinin post-natally causes constriction and eventual atrophy of the ductus arteriosus, forming the ... ligamentum arteriosum between the pulmonary trunk and aortic arch. It also plays a role in the constriction and eventual ...

https://en.wikipedia.org/wiki/Bradykinin

... ductus arteriosus, atrial septal defect). Complex defects are those that occur with other anatomical anomalies or require non- ... Burakovsky, V. I., Falkovsky, G. E., & Ivanitsky, A. V. (1984). Surgical repair of truncus arteriosus. Pediatric cardiology, 5( ...

https://en.wikipedia.org/wiki/Aortopulmonary_septal_defect

... foramen oval and ductus arteriosus) are allowed to close, he or she may go into shock." Signs of shock can include cool or ...

https://en.wikipedia.org/wiki/Hypoplastic_right_heart_syndrome

In conjunction with the other fetal shunts, the foramen ovale and ductus arteriosus, it plays a critical role in preferentially ... The ductus venosus is open at the time of birth and that is the reason why umbilical vein catheterization works. The ductus ... with no significant correlation to the closure of the ductus arteriosus or the condition of the infant. Possibly, increased ... If the ductus venosus fails to occlude after birth, it remains patent (open), and the individual is said to have a patent ...

https://en.wikipedia.org/wiki/Ductus_venosus

... patent ductus arteriosus, bicuspid aortic valve, and lung abnormalities. On chest X-ray, the heart looks posteriorly rotated. ...

https://en.wikipedia.org/wiki/Pericardium

... ductus arteriosus apertus, ventricular septal defect, atrial septal defect)". 1959: Senior physician at the 1st Medical Clinic ... ductus arteriosus apertus, ventricular septal defect, atrial septal defect)). 1958. (Habilitation thesis) Angeborene Herz- und ... Ductus arteriosus apertus, Ventrikelseptumdefekt, Vorhofseptumdefekt) (Pulmonary hypertension in congenital heart defects with ... Ductus arteriosus apertus, Ventrikelseptumdefekt, Vorhofseptumdefekt). Arch f Kreislaufforschung 1958; 28: 1-55, doi:10.1007/ ...

https://en.wikipedia.org/wiki/Franz_Loogen

... defect occurring in knocking out BRG1 in smooth muscle development is heart complications such as an open ductus arteriosus ...

https://en.wikipedia.org/wiki/SMARCA4

The mother, who was 52 years old, had a ventricular septal defect, two of her daughters had patent ductus arteriosus, her ...

https://en.wikipedia.org/wiki/Distichiasis,_congenital_heart_defects_and_mixed_peripheral_vascular_anomalies

Mutations in MYH11 have been described in individuals with TAAD with patent ductus arteriosus (PDA). Of individuals with TAAD, ... in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus ...

https://en.wikipedia.org/wiki/Myosin-11

... closure of a patent ductus arteriosus, and angioplasty of the great vessels. Percutaneous valve replacement An alternative to ...

https://en.wikipedia.org/wiki/Interventional_cardiology

... bicuspid aortic valve or patent ductus arteriosus. The syndrome has a characteristic facial appearance which is similar to that ...

https://en.wikipedia.org/wiki/Okamoto_syndrome

... tract dorsolateral fasciculus dorsomedial nucleus of thalamus dorsum sellae dowager's hump ductless gland ductus ductus ... of humerus Trochlea of superior oblique trochlear nerve trochlear nucleus Trochlear process true vocal cords Truncus arteriosus ... palpebrae superioris levator scapulae muscle levator velum palatini muscle ligament ligament of Treitz ligamentum arteriosum ... cortex peristalsis peritoneal cavity peritoneum periventricular nucleus peroneal artery Persistent truncus arteriosus pes ...

https://en.wikipedia.org/wiki/Index_of_anatomy_articles

Patent ductus arteriosus (PDA) is a congenital condition in babies that causes heart and lung problems. PDA treatment includes ... What is patent ductus arteriosus (PDA)?. Patent ductus arteriosus (PDA) is a heart condition in babies. It happens when a blood ... Patent Ductus Arteriosus (PDA) Patent ductus arteriosus (PDA) is a heart condition that affects some babies (more often, those ... What are patent ductus arteriosus symptoms?. PDA symptoms vary according to patent ductus arteriosus types. Small PDAs may not ...

https://my.clevelandclinic.org/health/diseases/17325-patent-ductus-arteriosus-pda

... is a condition in which the ductus arteriosus does not close. The word patent means open. ... Patent ductus arteriosus (PDA) is a condition in which the ductus arteriosus does not close. The word "patent" means open. ... The ductus arteriosus is a blood vessel that allows blood to go around the babys lungs before birth. Soon after the infant is ... However, if the baby has certain other heart problems or defects, keeping the ductus arteriosus open may be lifesaving. ...

https://medlineplus.gov/ency/article/001560.htm

Patent ductus arteriosus (PDA), in which there is a persistent communication between the descending thoracic aorta and the ... pulmonary artery that results from failure of normal physiologic closure of the fetal ductus (see image below), is one of the ... more common congenital heart defects.{file42617}The patient presentation of patent ductus arter... ... encoded search term (Patent Ductus Arteriosus (PDA)) and Patent Ductus Arteriosus (PDA) What to Read Next on Medscape ...

https://www.medscape.com/answers/891096-69159/what-are-the-treatment-options-for-patent-ductus-arteriosus-pda

If it stays open, the result is a condition called patent ductus arteriosus (PDA). ... The ductus arteriosus is a blood vessel that connects two major arteries before birth and normally closes after a baby is born ... What Is Patent Ductus Arteriosus?. Patent ductus arteriosus (PDA) is an extra blood vessel found in babies before birth and ... What Happens in Patent Ductus Arteriosus?. The ductus arteriosus is a normal blood vessel that connects two major arteries - ...

https://www.kidshealth.org/en/parents/patent-ductus-arteriosus.html

https://kidshealth.org/en/parents/patent-ductus-arteriosus.html

Comparison of oral ibuprofen and indomethacin on closure of patent ductus arteriosus in preterm infants ... Although intravenous indomethacin and ibuprofen are widely used for closure of patent ductus arteriosus in premature infants, ...

https://extranet.who.int/iris/restricted/browse?authority=Ductus+Arteriosus%2C+Patent&type=mesh

... ... Although intravenous indomethacin and ibuprofen are widely used for closure of patent ductus arteriosus in premature infants, ... Comparison of oral ibuprofen and indomethacin on closure of patent ductus arteriosus in preterm infants. EMHJ - Eastern ...

https://apps.who.int/iris/handle/10665/117446

The Patent Ductus Arteriosus (PDA) is a normal structure in the fetus. It functions… ... Patent Ductus Arteriosus (PDA). The Patent Ductus Arteriosus (PDA) is a normal structure in the fetus. It functions as a ... In some cases of cyanotic (blue baby) congenital heart disease, the ductus arteriosus must remain open to keep the baby alive. ...

https://cochranfirm.com/patent-ductus-arteriosus-pda/

Dog Health Article on Patent Ductus Arteriosus (PDA) ... Types of Patent Ductus Arteriosus. There are two types of ... Patent Ductus Arteriosus: left-to-right and right-to-left.. Left-to right Patent Ductus Arteriosus is the more common. This ... the puppy has a Patent Ductus Arteriosus, which is the most common congenital heart defect.. Breeds Affected by Patent Ductus ... to minimize the effects the Patent Ductus Arteriosus has had on the heart and lungs.. Typically, right-to-left Patent Ductus ...

http://www.qualitydogs.com/dog-articles/Dog-Health/patent-ductus-arteriosus.html

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes. The safety and scientific ... Patent ductus arteriosus (PDA), very common in preterm infants, is the delayed closure of a fetal blood vessel that limits ... Patent Ductus Arteriosus in Preterm Infants. Pediatrics. 2016 Jan;137(1). doi: 10.1542/peds.2015-3730. Epub 2015 Dec 15. ... Variation of Patent Ductus Arteriosus Treatment in Very Low Birth Weight Infants. Pediatrics. 2021 Nov;148(5):e2021052874. doi ...

https://clinicaltrials.gov/ct2/show/NCT03782610

Patent ductus arteriosus w left to right shunt. *Patent ductus arteriosus w right to left shunt ... Patent ductus arteriosus with left to right shunt. *Patent ductus arteriosus with left-to-right shunt ... Patent ductus arteriosus with right to left shunt. *Patent ductus arteriosus with right-to-left shunt ...

http://www.icd9data.com/2014/Volume1/740-759/747/747.0.htm

i ,Objective,/i,. To identify factors affecting closure of patent ductus arteriosus (PDA) in newborn infants born at 22– ... reversing the fetal right to left flow through the ductus arteriosus and foramen ovale [22]. The normal physiological ductus ... G. G. Dudell and W. M. Gersony, "Patent ductus arteriosus in neonates with severe respiratory disease," Journal of Pediatrics, ... R. I. Clyman, "Mechanisms regulating the ductus arteriosus," Biology of the Neonate, vol. 89, no. 4, pp. 330-335, 2006. ...

https://www.hindawi.com/journals/ccrp/2012/715265/

This is a known case of patent ductus arteriosus (PDA) managed by endovascular closure. Treatment of PDA can be medical ( ... This is a known case of patent ductus arteriosus (PDA) managed by endovascular closure. Treatment of PDA can be medical ( ... Patent ductus arteriosus closure device. Case contributed by Pir Abdul Ahad Aziz Qureshi ◉ ... Qureshi P, Patent ductus arteriosus closure device. Case study, Radiopaedia.org (Accessed on 08 Dec 2022) https://doi.org/ ...

https://radiopaedia.org/cases/patent-ductus-arteriosus-closure-device-2?iframe=true&lang=us

Comparison of oral ibuprofen and indomethacin on closure of patent ductus arteriosus in preterm infants ... Patent ductus arteriosus (PDA) is one of the most common clinical findings and most frequent source of complications in ... Comparison of oral ibuprofen and indomethacin on closure of patent ductus arteriosus in preterm infants ... Prophylaxis of patent ductus arteriosus with ibuprofen in preterm infants. Acta paediatrica, 2000, 89(11):1369-74. ...

http://www.emro.who.int/emhj-volume-14-2008/volume-14-issue-2/article14.html

If it stays open, the result is a condition called patent ductus arteriosus (PDA). - v1 ... The ductus arteriosus is a blood vessel that connects two major arteries before birth and normally closes after a baby is born ... What Is Patent Ductus Arteriosus?. Patent ductus arteriosus (PDA) is an extra blood vessel found in babies before birth and ... What Happens in Patent Ductus Arteriosus?. The ductus arteriosus is a normal blood vessel that connects two major arteries - ...

https://www.hopkinsallchildrens.org/Patients-Families/Health-Library/HealthDocNew/Patent-Ductus-Arteriosus-

BACKGROUND: Patent ductus arteriosus (PDA) occurs in 70% of extremely low birth weight (ELBW, birth weight ,1000 g) infants. ... N2 - BACKGROUND: Patent ductus arteriosus (PDA) occurs in 70% of extremely low birth weight (ELBW, birth weight ,1000 g) ... AB - BACKGROUND: Patent ductus arteriosus (PDA) occurs in 70% of extremely low birth weight (ELBW, birth weight ,1000 g) ... Failure of the ductus arteriosus to close has been associated with multiple morbidities. OBJECTIVE: To examine variability over ...

https://pennstate.pure.elsevier.com/en/publications/variation-and-comparative-effectiveness-of-patent-ductus-arterios

Patent ductus arteriosus (PDA) often requires surgical intervention in neonates and infants. During PDA closure, ... Yoshida, T., Anada, N. & Nakajima, Y. Residual shunt in an infant following patent ductus arteriosus ligation detected via ... Residual shunt in an infant following patent ductus arteriosus ligation detected via transesophageal echocardiography ... Residual shunt in an infant following patent ductus arteriosus ligation detected via transesophageal echocardiography ...

https://link.springer.com/article/10.1186/s40981-019-0240-3

Patent Ductus Arteriosus (PDA) is common in newborn infants, especially premature infants. During pregnancy, the Ductus ... Randomised Placebo-Controlled Trial of Early Targeted Treatment of Patent Ductus Arteriosus with Paracetamol in Extremely Low ... Arteriosus is an open channel between the two main blood vessels coming from the babys heart. After birth it usually closes ...

https://www.hrb.ie/funding/approved-awards/awards-approved/award/randomised-placebo-controlled-trial-of-early-targeted-treatment-of-patent-ductus-arteriosus-with-par-1/

Effect of patency of the ductus arteriosus on blood pressure in very preterm infants. ... Effect of patency of the ductus arteriosus on blood pressure in very preterm infants. ...

https://adc.bmj.com/content/67/10_Spec_No/1169.responses

Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit ... Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit ... Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit ...

https://fn.bmj.com/content/94/1/F48.share

patent ductus arteriosus Last edited 05/2022. The ductus arteriosus is a normal vascular channel during intrauterine life. It ... The ductus arteriosus normally closes within the first 48 hours of life. If it remains patent longer than this it is unlikely ... ductus arteriosus connects the main pulmonary artery to the proximal descending aorta, allowing the vast majority of right ... note that the ductus arteriosus frequently fails to close in the preterm infant, with an inverse relationship between ...

https://gpnotebook.com/simplepage.cfm?ID=-1617297404&linkID=45688

Learn and reinforce your understanding of Patent ductus arteriosus. ... Patent ductus arteriosus Videos, Flashcards, High Yield Notes, & Practice Questions. ...

https://www.osmosis.org/learn/Patent_ductus_arteriosus?from=/md/organ-systems/cardiovascular-system/pathology/heart-failure

The ductus arteriosus (DA) is a blood vessel that, in the developing fetus, connects the left pulmonary artery to the aorta, ... Patent Ductus Arteriosus (PDA). The ductus arteriosus (DA) is a fetal blood vessel connecting the left pulmonary artery ... Histological changes turn ductus into ligamentum arteriosum Ligamentum arteriosum Prenatal and Postnatal Physiology of the ... The ductus arteriosus (DA) is a fetal blood vessel connecting the left pulmonary artery Pulmonary artery The short wide vessel ...

https://www.lecturio.com/concepts/patent-ductus-arteriosus-pda/

Surgical management of an aberrant left subclavian artery originating from a left patent ductus arteriosus in a dog with a ... and abnormal branching with an aberrant left subclavian artery originating from the ampulla of a left patent ductus arteriosus ...

https://avmi.net/information/ct-concepts/surgical-management-of-an-aberrant-left-subclavian-artery-originating-from-a-left-patent-ductus-arteriosus-in-a-dog-with-a-right-aortic-arch-and-abnormal-branching/

Thoracotomy Versus Sternotomy for Patent Ductus Arteriosus Closure in Preterm Neonates. Arjan J F P Verhaegh, Ryan E Accord, ... Thoracotomy Versus Sternotomy for Patent Ductus Arteriosus Closure in Preterm Neonates. / Verhaegh, Arjan J F P; Accord, Ryan E ... Thoracotomy Versus Sternotomy for Patent Ductus Arteriosus Closure in Preterm Neonates. In: Annals of thoracic surgery. 2020 ; ... Thoracotomy Versus Sternotomy for Patent Ductus Arteriosus Closure in Preterm Neonates. Annals of thoracic surgery. 2020 jan; ...

https://research.rug.nl/nl/publications/thoracotomy-versus-sternotomy-for-patent-ductus-arteriosus-closur

5.10 Premature Closure of Fetal Ductus Arteriosus. Meloxicam may cause premature closure of the fetal ductus arteriosus. Avoid ... 5.10 Premature Closure of Fetal Ductus Arteriosus 5.11 Hematologic Toxicity 5.12 Masking of Inflammation and Fever 5.13 ... Premature Closure of Fetal Ductus Arteriosus: Avoid use in pregnant women starting at 30 weeks gestation (5.10, 8.1) ... Use of NSAIDs during the third trimester of pregnancy increases the risk of premature closure of the fetal ductus arteriosus. ...

https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=dfaac71c-dcc5-4b57-bf3b-616fccab96de

Indomethacin therapy in premature infants with patent ductus arteriosus and oliguria. T. F. Yeh, A. Wilks, J. Luken, E. S. ... Indomethacin therapy in premature infants with patent ductus arteriosus and oliguria. / Yeh, T. F.; Wilks, A.; Luken, J. et al. ... Yeh, TF, Wilks, A, Luken, J & Pildes, ES 1986, Indomethacin therapy in premature infants with patent ductus arteriosus and ... Indomethacin therapy in premature infants with patent ductus arteriosus and oliguria. In: Developmental Pharmacology and ...

https://tmu.pure.elsevier.com/en/publications/indomethacin-therapy-in-premature-infants-with-patent-ductus-arte-2

Background: Persistent Ductus Arteriosus (PDA) is a vascular structure that connects the pulmonary artery and the descending ... Therapeutic Modalities in the Treatment of Persistent Ductus Arteriosus in Premature Babies: Report of Two Cases. Mediha ... Results and Discussion: The ductus closes functionally within the first 72 to 96 hours after the birth. Its anatomical closure ... with hemodynamically significant ductus, different timing of treatment and different therapeutic options. ...

https://www.bibliomed.org/?mno=140285

Patent Ductus Arteriosus. In the fetus, oxygenation of the blood is accomplished by the placenta, making blood flow through the ... The ductus arteriosus is a conduit between the left pulmonary artery and the aorta that results in shunting of blood away from ... Patent ductus arteriosus and its treatment as risk factors for neonatal and neurodevelopmental morbidity. Pediatrics. 2007 Jun ... Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev ...

http://emedicine.medscape.com/article/979717-overview

The use of transesophageal echocardiography to evaluate the effectiveness of patent ductus arteriosus ligation. (springer.com)

However, it was not until 1888 that Munro conducted the dissection and ligation of the ductus arteriosus in an infant cadaver, and it would be another 50 years before Robert E. Gross successfully ligated a patent ductus arteriosus (PDA) in a 7-year-old child. (medscape.com)
The surgery itself is quite intense, requiring a 2-inch incision under the baby's left arm, lung deflation, ventilatory support and ductus ligation. (childrenswi.org)
The authors of a recent article on PDA ligation in the Journal of Cardiothoracic Surgery wrote that "while eliminating the detrimental effects of a PDA on lung development, (surgery) may create its own set of problems that counteract many of the benefits derived from ductus closure. (childrenswi.org)

What causes patent ductus arteriosus? (clevelandclinic.org)

What are patent ductus arteriosus symptoms? (clevelandclinic.org)

Effect of fluid administration on the development of symptomatic patent ductus arteriosus and congestive heart failure in premature infants. (gpnotebook.com)
9. Evans P, O'Reilly D, Flyer JN, Soll R, Mitra S. Indomethacin for symptomatic patent ductus arteriosus in preterm infants. (alomedika.com)

Although intravenous indomethacin and ibuprofen are widely used for closure of patent ductus arteriosus in premature infants, these formulations are unavailable in the Islamic Republic of Iran. (who.int)
Patent ductus arteriosus (PDA), very common in preterm infants, is the delayed closure of a fetal blood vessel that limits blood flow through the lungs. (clinicaltrials.gov)
To identify factors affecting closure of patent ductus arteriosus (PDA) in newborn infants born at 22-27 weeks gestational age (GA) during pharmacological treatment with cyclooxygenase inhibitors. (hindawi.com)
Infants born before 28 gestational weeks have a high incidence of patent ductus arteriosus (PDA) [ 1 , 2 ]. (hindawi.com)
The objective of this retrospective study was to identify factors associated with closure of the ductus arteriosus during treatment with cyclooxygenase inhibitors in infants born at 22-27 weeks GA, with special focus on ventilatory and pulmonary circulatory factors. (hindawi.com)
Patent ductus arteriosus (PDA) is one of the most common clinical findings and most frequent source of complications in premature infants [1]. (who.int)
Patent ductus arteriosus (PDA) often requires surgical intervention in neonates and infants. (springer.com)
Patent Ductus Arteriosus (PDA) is common in newborn infants, especially premature infants. (hrb.ie)
Effect of patency of the ductus arteriosus on blood pressure in very preterm infants. (bmj.com)
It's smaller than a pea, yet Children's Wisconsin pediatric interventional cardiologist Todd Gudausky, MD, calls the Amplatzer Piccolo Occluder "a real game changer" for premature infants with patent ductus arteriosus (PDA), a potentially life-threatening opening between two blood vessels leading from the heart. (childrenswi.org)
Failure of the ductus to close is common in premature infants but rare in full-term babies. (pyrogeography.org)
Neonatal Intensive Care Unit-Level Patent Ductus Arteriosus Treatment Rates and Outcomes in Infants Born Extremely Preterm. (bvsalud.org)
Widened pulse pressure is a classic sign of significant left-to-right shunting patent ductus arteriosus (PDA), but little evidence supports this statement in the early life of premature infants with respiratory distress syndrome (RDS) needing nonsteroidal antiinflammatory drugs (NSAIDs), the pharmacological treatment for PDA. (unipd.it)
Background Early diagnosis and effective treatment of the patent ductus arteriosus (PDA) in infants less than 32 weeks gestation remains contentious. (bmj.com)

Pulmonary factors such as prenatal steroid exposure and RDS thus appear to affect the closure of the ductus arteriosus, and parameters related to pulmonary circulation, for example, high PaO 2 and low blood pressure within the ductus arteriosus, relate to physiological ductal constriction in animal studies [ 19 ]. (hindawi.com)

Patent ductus arteriosus (PDA) may also exist with other cardiac anomalies, which must be considered at the time of diagnosis. (medscape.com)
The lungs are frequently underdeveloped and cardiac defects such as septal openings, patent ductus arteriosus and transposition of great vessels are common. (arizona.edu)

Although a left ductus arteriosus is a normal structure during normal fetal development, the presence of a right ductus arteriosus is usually associated with other congenital abnormalities of the cardiovascular system, most typically involving the aortic arch or conotruncal development. (medscape.com)
EGME caused a dose dependent increase in fetal cardiovascular malformations, primarily ventricular septal defects and right ductus arteriosus. (cdc.gov)

One way for this to happen is that blood flows from the main heart artery ( aorta ) to the primary lung artery ( pulmonary arteries ) through a special fetal blood vessel (ductus arteriosus). (clevelandclinic.org)
Patent ductus arteriosus (PDA), in which there is a persistent communication between the descending thoracic aorta and the pulmonary artery that results from failure of normal physiologic closure of the fetal ductus (see image below), is one of the more common congenital heart defects. (medscape.com)
Schematic diagram of a left-to-right shunt of blood flow from the descending aorta via the patent ductus arteriosus (PDA) to the main pulmonary artery. (medscape.com)
During fetal life, the ductus arteriosus is a normal structure that allows most of the blood leaving the right ventricle to bypass the pulmonary circulation and pass into the descending aorta. (medscape.com)
The ductus arteriosus is a remnant of the distal sixth aortic arch and connects the pulmonary artery at the junction of the main pulmonary artery and the origin of the left pulmonary artery to the proximal descending aorta just after the origin of the left subclavian artery. (medscape.com)
An anatomic marker of the ductus is the recurrent laryngeal nerve, which nerve typically arises from the vagus nerve just anterior and caudal to the ductus and loops posteriorly around the ductus to ascend behind the aorta en route to the larynx. (medscape.com)
Structures that have been mistaken for the patent ductus arteriosus (PDA) in surgical procedures include the aorta, the pulmonary artery, and the carotid artery. (medscape.com)
The ductus arteriosus is a normal blood vessel that connects two major arteries - the aorta and the pulmonary artery - that carry blood away from the heart. (kidshealth.org)
That mechanism is the Ductus Arteriosus, a "shunt" (bypass) from the pulmonary artery to the descending aorta. (qualitydogs.com)
Background: Persistent Ductus Arteriosus (PDA) is a vascular structure that connects the pulmonary artery and the descending aorta. (bibliomed.org)
A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. (jefferson.edu)
The classic patent ductus arteriosus (PDA) connects the junction of the main pulmonary artery and the left pulmonary artery with the aorta just below and opposite the left subclavian artery. (medscape.com)
If the magnitude of the left-to-right shunt is large, continued flow around the aortic arch into the ductus arteriosus in diastole and flow reversal in the descending aorta are evident. (medscape.com)
The ductus arteriosus is a normal fetal artery connecting the aorta and the main lung artery (pulmonary artery). (pyrogeography.org)
Our notes say that a ductus arteriosus allows flow from the pulmonary artery to the aorta, which I knew. (dentalstudentpathology.com)
A. When we talk about the ductus allowing flow from the pulmonary artery (right) to aorta (left), we're talking about intrauterine flow through the ductus. (dentalstudentpathology.com)
Before birth, the pressure on the right side of the heart is greater than the pressure on the left - so blood flows from pulmonary artery to aorta (through the ductus). (dentalstudentpathology.com)
The ductus arteriosus is a small fetal structure that connects two large arteries (aorta and pulmonary) but becomes pathological when it is maintained after birth. (bvsalud.org)

With a small or moderate-sized patent ductus arteriosus (PDA), the left ventricular size is often normal, but as shunt magnitude increases, the left ventricular diastolic size also increases. (medscape.com)
A congenital defect (e.g., inherited at birth) of the heart (such as ventricular septal defect, patent ductus arteriosis, subaortic steonosis, etc. (drjustinelee.com)
Simples congenital heart anomalies like atrial and ventricular septum defects, ductus arteriosus or pulmonary vein transposition lead to the formation of a left-to-right shunt. (bme.hu)

premature babies, persistent ductus arteriousus. (bibliomed.org)
Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart. (healthtopquestions.com)
Morbidities associated with persistent patent ductus arteriosus (PDA) may lead to the conclusion that the best approach is early surgical treatment. (bvsalud.org)
Approximately half of babies born at less than 32 weeks of gestational age have persistent patent ductus arteriosus (PDA), a condition associated with higher odds of death and respiratory morbidity. (pediatricsnationwide.org)
Serial echocardiogram was done, and the baby was found to have Patent Ductus Arteriosus (a persistent opening between the two major blood vessels leading from the heart), which was resolved medically. (thereportingtoday.com)

The ductus arteriosus (DA) is a fetal blood vessel connecting the left pulmonary artery Pulmonary artery The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs. (lecturio.com)
By 2-dimensional (2-D) echocardiography, the aortic end of the patent ductus arteriosus (PDA) is localized first, and then it is tracked back to the pulmonary artery. (medscape.com)

atrial septal defect and patent ductus arteriosus in one report. (mhmedical.com)

However, if the baby has certain other heart problems or defects, keeping the ductus arteriosus open may be lifesaving. (medlineplus.gov)
In the presence of complex congenital heart defects, the usual anatomy of the ductus may not be present. (medscape.com)
A persistently patent ductus is a common congenital heart lesion, occurring either singly or in combination with other defects. (gpnotebook.com)
Patent ductus arteriosus (PDA) is one of the most frequent congenital heart defects and may occur as an isolated lesion or in association with others. (revportcardiol.org)

In neonates with severe pulmonary stenosis, the pulmonary blood flow depends on the patency of the ductus arteriosus. (medscape.com)

Typically, the ductus has a conical shape with a large aortic end tapering into the small pulmonary connection. (medscape.com)
The dog in this report had a right aortic arch and abnormal branching with an aberrant left subclavian artery originating from the ampulla of a left patent ductus arteriosus (PDA) that was detected with CTA. (avmi.net)

A large ductus arteriosus could cause hypercarbia and hypoxemia from congestive heart failure (CHF) and air space disease (atelectasis or intra-alveolar fluid/pulmonary edema). (medscape.com)

Objective: The aim of this paper is to present two cases from Neonatology of Cantonal hospital in Bihac, with hemodynamically significant ductus, different timing of treatment and different therapeutic options. (bibliomed.org)

When a newborn breathes and begins to use the lungs, the ductus is no longer needed and usually closes by itself during the first 2 days after birth. (kidshealth.org)
The ductus arteriosus normally closes within the first 48 hours of life. (gpnotebook.com)
Results and Discussion: The ductus closes functionally within the first 72 to 96 hours after the birth. (bibliomed.org)
In most babies, the ductus closes (probably in response to the new levels of oxygen in the blood). (dentalstudentpathology.com)

If it fails to close completely, still allowing blood to flow through, the puppy has a Patent Ductus Arteriosus, which is the most common congenital heart defect. (qualitydogs.com)

In many cases, the diagnosis and treatment of a patent ductus arteriosus (PDA) is critical for survival in neonates with severe obstructive lesions to either the right or left side of the heart. (medscape.com)
Background: To date, a posterolateral thoracotomy approach is considered the gold standard for surgical closure of patent ductus arteriosus (PDA), also in preterm neonates. (rug.nl)
The hospital mortality of patent ductus arteriosus closure is not low in extremely low birth weight premature neonates (less than 1 kg), because of prematurity, including enterocolitis, sepsis, heart failure, and late respiratory failure. (ismics.org)

The ductus arteriosus is a hole that allows the blood to skip the circulation to the lungs. (pyrogeography.org)
If the ductus arteriosus is still open (or patent) the blood may skip this necessary step of circulation. (pyrogeography.org)

Patent ductus arteriosus (PDA) is a heart condition that affects some babies (more often, those born prematurely). (clevelandclinic.org)
Patent ductus arteriosus (PDA) is a heart condition in babies. (clevelandclinic.org)
What happens in babies with patent ductus arteriosus? (clevelandclinic.org)
Patent ductus arteriosus (PDA) is an extra blood vessel found in babies before birth and just after birth. (kidshealth.org)
In some babies, the ductus arteriosus does not close soon after birth. (nicuapp.com)
In premature newborn babies, medicine can often help the ductus close. (pyrogeography.org)

It happens when a blood vessel called the ductus arteriosus doesn't close as it should after birth. (clevelandclinic.org)
The ductus arteriosus is a blood vessel that allows blood to go around the baby's lungs before birth. (medlineplus.gov)
Failure of the vessel to close and involute within 72 hours of birth results in a condition called patent ductus arteriosus (PDA). (lecturio.com)
This blood vessel is called the ductus arteriosus [duck-tus ar-tear-ee-oh-sis]. (nicuapp.com)
There it can be positioned within the ductus to plug the blood vessel. (childrenswi.org)
Fetal dogs have a short, broad vessel called the ductus arteriosus, which sends blood. (gopetsamerica.com)

IMSEAR at SEARO: Familial patent ductus arteriosus. (who.int)
Familial patent ductus arteriosus. (who.int)

The ductus arteriosus is a normal vascular channel during intrauterine life. (gpnotebook.com)

The management of the patent ductus arteriosus (PDA) is straightforward from a surgical technique standpoint but complex from a medical decision standpoint. (pedsurglibrary.com)
To analyze the clinical and surgical profile of preterm newborns submitted to selective correction surgery of the patent ductus arteriosus. (bvsalud.org)
To assess associations between neonatal intensive care unit (NICU)-level patent ductus arteriosus (PDA) treatment rates (pharmacologic or surgical) and neonatal outcomes. (bvsalud.org)

Patent ductus arteriosus (PDA) causes problems with blood flow between the heart and lungs. (clevelandclinic.org)
The ductus arteriosus carries blood away from the lungs and sends it directly to the body. (kidshealth.org)
Right-to-left Patent Ductus Arteriosus is less common, and it occurs when blood continues to flow through the shunt in the same direction it did before birth, when its purpose was to bypass the lungs. (qualitydogs.com)
During pregnancy, the Ductus Arteriosus is an open channel between the two main blood vessels coming from the baby's heart. (hrb.ie)
The ductus allows blood to detour away from the lungs before birth. (pyrogeography.org)
Which direction does blood flow through the ductus arteriosus? (dentalstudentpathology.com)
Here's a great question from last year that helps sort out the issue of which way blood flows through the ductus arteriosus. (dentalstudentpathology.com)
If the ductus is widely patent, then after a while, that left to right shunt can put enough pressure on the lungs that they react by closing down vessels, effectively making it more difficult to push blood through. (dentalstudentpathology.com)
Patent ductus arteriosus (PDA) is a condition in which a connection between two major blood vessels close to the heart does not close properly after birth. (nih.gov)

If significant left-to-right shunt through the patent ductus arteriosus (PDA) is present, the pulmonary arteries, pulmonary veins, left atrium, and left ventricle are enlarged on chest films. (medscape.com)

The diagnosis of patent ductus arteriosus (PDA) is almost always based on careful clinical evaluation, including physical examination showing the characteristic murmur, typical electrocardiographic (ECG) abnormalities, radiographic changes, and echocardiographic/Doppler findings. (medscape.com)
The echocardiographic findings are typically diagnostic for patent ductus arteriosus (PDA). (medscape.com)

Other associated conditions include hypocalvaria, intrauterine growth retardation (IUGR), and patent ductus arteriosus (PDA). (cdc.gov)

Soon after the infant is born and the lungs fill with air, the ductus arteriosus is no longer needed. (medlineplus.gov)
If the PDA (ductus) is small, it doesn't make the heart and lungs work harder. (pyrogeography.org)

When doctors choose to close the ductus, a percutaneous approach is considered the standard of care beyond 1 to 2 years of age. (pediatricsnationwide.org)

Detection of residual flow by transesophageal echocardiography during video-assisted thoracoscopic patent ductus arteriosus interruption. (springer.com)
Echocardiography is the primary diagnostic study used to evaluate and diagnose patent ductus arteriosus (PDA). (medscape.com)

Ibuprofen and patent ductus arteriosus. (gpnotebook.com)

When a baby has a PDA, the ductus arteriosus doesn't close properly. (clevelandclinic.org)
Patent ductus arteriosus (PDA) is a condition in which the ductus arteriosus does not close. (medlineplus.gov)
If the ductus doesn't close, the result is a patent (meaning "open") ductus arteriosus. (kidshealth.org)
When a puppy is born and begins breathing on his own, the Ductus Arteriosus should close. (qualitydogs.com)
Failure of the ductus arteriosus to close has been associated with multiple morbidities. (elsevier.com)
The goal of treatment is to close the ductus arteriosus. (nicuapp.com)
PDA (patent ductus arteriosus) - a heart problem in which the ductus arteriosus does not close soon after birth. (nicuapp.com)
Sometimes, the ductus doesn't close after birth. (pyrogeography.org)
The figure below on the left shows one example of how a catheterization is used to close the ductus. (pyrogeography.org)
After the first few weeks of life, medicine won't work as well to close the ductus and surgery may be required. (pyrogeography.org)

In isolated patent ductus arteriosus (PDA), signs and symptoms are consistent with left-to-right shunting. (medscape.com)

Patent ductus arteriosus is the most common heart condition in newborns. (clevelandclinic.org)
Your provider may hear a patent ductus arteriosus heart murmur during a well-baby care visit or physical examination. (clevelandclinic.org)
In some cases of cyanotic (blue baby) congenital heart disease, the ductus arteriosus must remain open to keep the baby alive. (cochranfirm.com)
With right-to-left Patent Ductus Arteriosus, there is often little or no heart murmur, so the condition may be missed on a routine exam, which means noticeable physical signs may be the first indication of the condition. (qualitydogs.com)
For left-to-right Patent Ductus Arteriosus, surgery is recommended, as early as possible, before significant changes to the heart have occurred. (qualitydogs.com)
The self-expanding wire mesh device is threaded through the femoral vein to the heart and through the pulmonary valve into the ductus arteriosus. (childrenswi.org)
Rayyan Ali 6 months old male child was suffering from Moderate PDA (patent ductus arteriosus - a congenital heart disease). (transparenthands.org)

See also Patent Ductus Arteriosus Surgery and Eisenmenger Syndrome . (medscape.com)
Patent Ductus Arteriosus is a topic covered in the Pediatric Surgery NaT . (pedsurglibrary.com)
APSA Webapp , www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829072/all/Patent_Ductus_Arteriosus. (pedsurglibrary.com)
Preterm newborns undergoing selective correction surgery of the patent ductus arteriosus: is there still space for these procedures? (bvsalud.org)

Patent Ductus Arteriosus is in the category of conditions where one of those necessary fetal structures remains after birth, when it should have naturally gone away or ceased its function. (qualitydogs.com)

Anatomy10

Organisms4

Diseases30

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes7

Technology, Industry, Agriculture1

Named Groups5

Health Care4

Prenatal features of ductus arteriosus constriction and restrictive foramen ovale in d-transposition of the great arteries. (1/253)

Inducible NO synthase inhibition attenuates shear stress-induced pulmonary vasodilation in the ovine fetus. (2/253)

Cyclooxygenase-2 plays a significant role in regulating the tone of the fetal lamb ductus arteriosus. (3/253)

The effects of maternal indomethacin therapy on human fetal branch pulmonary arterial vascular impedance. (4/253)

Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle. (5/253)

Coanda effect on ductal flow in the pulmonary artery. (6/253)

Fate of the stented arterial duct. (7/253)

Ductus venosus blood velocity in persistent pulmonary hypertension of the newborn. (8/253)

Ductus Arteriosus, Patent

Ductus Arteriosus

Truncus Arteriosus, Persistent

Infant, Newborn

Infant, Premature

Indomethacin

Truncus Arteriosus

Infant, Premature, Diseases

Septal Occluder Device

Pulmonary Artery

Cardiac Catheterization

Ibuprofen

Heart Murmurs

Heart Defects, Congenital

Endarteritis

Ligation

Gestational Age

Echocardiography, Doppler, Color

Heart Septal Defects, Ventricular

Prostheses and Implants

Fetus

Infant, Very Low Birth Weight

Echocardiography, Doppler

Pregnancy

Fetal Heart

Balloon Occlusion

Pulmonary Circulation

Aortic Coarctation

Aortography

Embolization, Therapeutic

Sheep

Aorta, Thoracic

Papio papio

Echocardiography

Ultrasonography, Prenatal

Abnormalities, Multiple

Infant, Extremely Low Birth Weight

Cardiovascular Surgical Procedures

Cardiovascular Agents

Fetal Diseases

Respiratory Distress Syndrome, Newborn

Persistent Fetal Circulation Syndrome

Aneurysm

Blood Flow Velocity

Cyclooxygenase Inhibitors

Bronchopulmonary Dysplasia

Lower Extremity Deformities, Congenital

Alprostadil

Cardiac Surgical Procedures

Eisenmenger Complex

Hypertension, Pulmonary

Oliguria

Animals, Newborn

Intensive Care Units, Neonatal

Treatment Outcome

Enterocolitis, Necrotizing

Recurrent Laryngeal Nerve Injuries

Angiocardiography

Pulmonary Valve Stenosis

Alloys

Oxygen

Tocolysis

Physiognomy

Heart Septum

Pulmonary Atresia

Heart Septal Defects

Aortic Arch Syndromes

Angiography

Heart Septal Defects, Atrial

Infant, Low Birth Weight

Tetralogy of Fallot

Anti-Inflammatory Agents, Non-Steroidal

Aorta

Retrospective Studies

Transcription Factor AP-2

Vascular Malformations

Pulmonary Valve

Pregnancy Trimester, Third

Vasoconstriction

Equipment Design