Analytical, Diagnostic and Therapeutic Techniques and Equipment
Drug Stability
Drug Stability
The chemical and physical integrity of a pharmaceutical product.

Analysis of gabapentin in serum and plasma by solid-phase extraction and gas chromatography-mass spectrometry for therapeutic drug monitoring. (1/4528)

A simple method for the determination of gabapentin (Neurontin) is described. The method uses solid-phase extraction by disk column and derivatization followed by gas chromatographic-mass spectrometric analysis. The single-step derivatization with MTBSTFA produces a t-BDMS derivative of both the carboxylic and amine moieties of the molecule. Each step of the procedure was optimized to assure reliable performance of the method. The assay limit of detection was 0.1 microg/mL with a linear range from 1.0 to 35 microg/mL. Within-run (n = 3) and between-run (n = 40) coefficients of variation were less than 8.2 and 15.9%, respectively. The method has proven reliable in routine production for more than a year, producing clean chromatography with unique ion fragments, consistent ion mass ratios, and no interferences. Statistical analysis of the gabapentin concentrations measured in 1020 random specimens over a 2-month period showed a mean concentration of 6.07 microg/mL with a standard deviation of 5.28.  (+info)

Nuclear location of mammalian DNA polymerase activities. (2/4528)

Nuclei were isolated from monolayer cultures of mouse and human cells using a nonaqueous procedure of cell fractionation in which lyophilized cells were homogenized and centrifuged in 100% glycerol. In previous work we have shown that the nuclear pellet and cytoplasmic supernatant fraction contained 10% or less of the nucleic acids characteristic of the other cell fraction. Aqueous extracts made from fresh cultures and from nonaqueous material at each step of the fractionation procedure were assayed fro DNA polymerase activity. Activities were normalized to DNA contents of extracted material. Specific activity was preserved quantitatively through freezing and drying the cells, but was found to be unstable in glycerol suspensions with approximate half-lives and 1 h at 23 degrees and 4 h at 0-4 degrees. Activities were relatively stable at -25 degrees, however, so that by homogenizing only 15 min at 4 degrees and centrifuging at -25 degrees we preserved approximately 85% of the specific activity of fresh cultures in the nonaqueous nuclear fraction. Sedimentation analyses showed that the nuclear fraction contained both DNA polymerase-alpha and-beta in approximately the proportions expected if all polymerase activities were confined to the nucleus in living cells. DNA polymerase-alpha was found to be more unstable in glycerol suspensions than DNA polymerase-beta. Nuclear location of both activities was found in exponential cultures and in 3T3 mouse cultures synchronized in the G1 and S phases of the cell division cycle. We found no evidence for cytoplasmic factors affecting nuclear polymerase activities. We have concluded that the two major DNA polymerases are nuclear although one, DNA polymerase-alpha, frequently is present as a weakly bound nuclear protein.  (+info)

Native display of complete foreign protein domains on the surface of hepatitis B virus capsids. (3/4528)

The nucleocapsid of hepatitis B virus (HBV), or HBcAg, is a highly symmetric structure formed by multiple dimers of a single core protein that contains potent T helper epitopes in its 183-aa sequence. Both factors make HBcAg an unusually strong immunogen and an attractive candidate as a carrier for foreign epitopes. The immunodominant c/e1 epitope on the capsid has been suggested as a superior location to convey high immunogenicity to a heterologous sequence. Because of its central position, however, any c/e1 insert disrupts the core protein's primary sequence; hence, only peptides, or rather small protein fragments seemed to be compatible with particle formation. According to recent structural data, the epitope is located at the tips of prominent surface spikes formed by the very stable dimer interfaces. We therefore reasoned that much larger inserts might be tolerated, provided the individual parts of a corresponding fusion protein could fold independently. Using the green fluorescent protein (GFP) as a model insert, we show that the chimeric protein efficiently forms fluorescent particles; hence, all of its structurally important parts must be properly folded. We also demonstrate that the GFP domains are surface-exposed and that the chimeric particles elicit a potent humoral response against native GFP. Hence, proteins of at least up to 238 aa can be natively displayed on the surface of HBV core particles. Such chimeras may not only be useful as vaccines but may also open the way for high resolution structural analyses of nonassembling proteins by electron microscopy.  (+info)

Specificity of native-like interhelical hydrophobic contacts in the apomyoglobin intermediate. (4/4528)

On exposure to mildly acidic conditions, apomyoglobin forms a partially folded intermediate, I. The A, B, G, and H helices are significantly structured in this equilibrium intermediate, whereas the remainder of the protein is largely unfolded. We report here the effects of mutations at helix pairing sites on the stability of I in three classes of mutants that: (i) truncate hydrophobic side chains in native helix packing sites, (ii) truncate hydrophobic side chains not involved in interhelical contacts, and (iii) extend hydrophobic side chains at residues not involved in interhelical contacts. Class I mutants significantly decrease the stability and cooperativity of folding of the intermediate. Class II and III mutants show smaller effects on stability and have little effect on cooperativity. Qualitatively similar results to those found in I were obtained for all three classes of mutants in native myoglobin (N), demonstrating that hydrophobic burial is fairly specific to native helix packing sites in I as well as in N. These results suggest that hydrophobic burial along native-like interhelical contacts is important for the formation of the cooperatively folded intermediate.  (+info)

Stretching lattice models of protein folding. (5/4528)

A new class of experiments that probe folding of individual protein domains uses mechanical stretching to cause the transition. We show how stretching forces can be incorporated in lattice models of folding. For fast folding proteins, the analysis suggests a complex relation between the force dependence and the reaction coordinate for folding.  (+info)

Stabilization of L-ascorbic acid by superoxide dismutase and catalase. (6/4528)

The effects of superoxide dismutase (SOD) and catalase on the autoxidation rate of L-ascorbic acid (ASA) in the absence of metal ion catalysts were examined. The stabilization of ASA by SOD was confirmed, and the enzyme activity of SOD, which scavenges the superoxide anion formed during the autoxidation of ASA, contributed strongly to this stabilization. The stabilization of ASA by catalase was observed for the first time; however, the specific enzyme ability of catalase would not have been involved in the stabilization of ASA. Such proteins as bovine serum albumin (BSA) and ovalbumin also inhibited the autoxidation of ASA, therefore it seems that non-specific interaction between ASA and such proteins as catalase and BSA might stabilize ASA and that the non-enzymatic superoxide anion scavenging ability of proteins might be involved.  (+info)

Incorporation rates, stabilities, cytotoxicities and release of liposomal tetracycline and doxycycline in human serum. (7/4528)

Tetracycline and doxycycline were encapsulated in cationic, anionic and neutral liposomes. The amounts of antibiotic encapsulated, the stability of each preparation at 4 degrees C for 4 weeks, and the kinetics of the release of entrapped drug into human sera were assessed by high-performance liquid chromatography. The toxicities of the liposome preparations on human erythrocytes and HeLa 229 cells were evaluated in vitro. The results showed that doxycycline was entrapped more efficiently than tetracycline, and that doxycycline-entrapped liposomes were more stable at 4 degrees C and in human sera, and less cytotoxic than tetracycline-entrapped liposomes.  (+info)

Interaction of asparagine and EGF in the regulation of ornithine decarboxylase in IEC-6 cells. (8/4528)

Our laboratory has shown that asparagine (ASN) stimulates both ornithine decarboxylase (ODC) activity and gene expression in an intestinal epithelial cell line (IEC-6). The effect of ASN is specific, and other A- and N-system amino acids are almost as effective as ASN when added alone. In the present study, epidermal growth factor (EGF) was unable to increase ODC activity in cells maintained in a salt-glucose solution (Earle's balanced salt solution). However, the addition of ASN (10 mM) in the presence of EGF (30 ng/ml) increased the activity of ODC 0.5- to 4-fold over that stimulated by ASN alone. EGF also showed induction of ODC with glutamine and alpha-aminoisobutyric acid, but ODC induction was maximum with ASN and EGF. Thus the mechanism of the interaction between ASN and EGF is important for understanding the regulation of ODC under physiological conditions. Therefore, we examined the expression of the ODC gene and those for several protooncogenes under the same conditions. Increased expression of the genes for c-Jun and c-Fos but not for ODC occurred with EGF alone. The addition of ASN did not further increase the expression of the protooncogenes, but the combination of EGF and ASN further increased the expression of ODC over that of ASN alone. Western analysis showed no significant difference in the level of ODC protein in Earle's balanced salt solution, ASN, EGF, or EGF plus ASN. Addition of cycloheximide during ASN and ASN plus EGF treatment completely inhibited ODC activity without affecting the level of ODC protein. These results indicated that 1) the increased expression of protooncogenes in response to EGF is independent of increases in ODC activity and 2) potentiation between EGF and ASN on ODC activity may not be due to increased gene transcription but to posttranslational regulation and the requirement of ongoing protein synthesis involving a specific factor dependent on ASN.  (+info)

Difference between revisions of Drug Stability Reporting - HL7Wiki
The project scope is to ballot a HL7 V3 Drug Stability Reporting (eStability) Release 2 Draft Standard for Trial Use (DSTU) message and the Implementation Guide (IG). The HL7 V3 Drug Stability Reporting (eStability) Release 1 is an approved HL7 and ANSI standard. Based on information gathered during the FDA pilot of Release 1 the message and IG were revised and Release 2 was proposed to be balloted as a DSTU. The scope includes: - Completion of DSTU testing and incorporation of changes or new requirements identified through DSTU testing. - Completion of IG. eStability Project Scope Statement ...
https://wiki.hl7.org/w/index.php?title=Drug_Stability_Reporting&diff=44615
Solution Stability - Plasma, Gastrointestinal, Bioassay | Bentham ScienceSolution Stability - Plasma, Gastrointestinal, Bioassay | Bentham Science
Title: Solution Stability - Plasma, Gastrointestinal, Bioassay. VOLUME: 9 ISSUE: 9. Author(s):Li Di and Edward H. Kerns. Affiliation:Wyeth Research, Princeton, NJ 08543-8000, USA.. Keywords:Plasma stability, solution stability, simulated gastro-intestinal fluids, stability-ph profile, high throughput, drug discovery, HPLC, LC-MS. Abstract: Solution stability of drug candidates in plasma, gastrointestinal fluids and bioassays is important in order to achieve low clearance, good oral bioavailability and have robust SAR. Screening of solution stability early in drug discovery can avoid pursuing hits with high risk of instability, prioritize chemical series, guide structural modification, and enhance the chance of project success. The conditions of solution stability methods are critical in generating relevant data and include: test compound concentration, enzyme source and preparation, limits of solubility, cosolvent, plasma protein binding effect, detection techniques (LC-UV vs. LC-MS), and what ...
https://www.eurekaselect.com/68023/article/solution-stability-plasma-gastrointestinal-bioassay?tracking-code=4
Development and validation of stability-indicating HPLC method for betamethoasone dipropionate and related substances in...Development and validation of stability-indicating HPLC method for betamethoasone dipropionate and related substances in...
Development and validation of stability-indicating HPLC method for betamethoasone dipropionate and related substances in topical formulation, AS Vairale, P Sivaswaroop, S Bandana
https://www.ijpsonline.com/articles/development-and-validation-of-stabilityindicating-hplc-method-for-betamethoasone-dipropionate-and-related-substances-in-topical-fo.html
Criteria for Judging the Quality of a Publication on Physicochemical Stability of Ready to Use Injectable Drugs<...
TY - JOUR. T1 - Criteria for Judging the Quality of a Publication on Physicochemical Stability of Ready to Use Injectable Drugs. AU - Hecq, Jean-Daniel. AU - Bihin, Benoit. AU - Jamart, Jacques. AU - Galanti, Laurence. PY - 2017/8/8. Y1 - 2017/8/8. N2 - In hospitals, a major part of the drugs is administered via the intravenous route. When one wants to evaluate or know the stability of a drug in solution, it is necessary to know several physico-chemical parameters. Several reference works are available to help the hospital pharmacist with this research. However, reading these different sources can make you discover conflicting data. It is therefore necessary at this time to obtain the publications with contradictory results and to read them again. Seven criteria have been identified for judging the quality of a publication on physicochemical stability: full description of equipment, methods and analytical conditions of molecules studied; complete description of the procedures used to validate ...
https://researchportal.unamur.be/en/publications/criteria-for-judging-the-quality-of-a-publication-on-physicochemi
Stabilization of eptifibatide by cosolvents<...
TY - JOUR. T1 - Stabilization of eptifibatide by cosolvents. AU - Zhao, Luwei. AU - Yalkowsky, Samuel H. PY - 2001/5/7. Y1 - 2001/5/7. N2 - Eptifibatide is a potent and highly specific inhibitor of platelet receptor glycoprotein IIb/IIIa and is indicated in the treatment of acute coronary syndrome. The commercial product Integrilin® (eptifibatide) Injection requires a cold/refrigerator storage condition. In an effort to improve the drug stability for room temperature storage and transportation, this study proposed a semi-aqueous formulation that contains 2 mg/ml eptifibatide, 10% ethanol, 40% propylene glycol and 50% 0.025 M citrate buffer. The stability study was conducted in the pH range 4.25-6.25 under accelerated temperatures: 48, 60, 72.5°C. The results indicate that the proposed semi-aqueous vehicles substantially increased the drug stability in comparison with aqueous vehicles. The predicted drug shelf-life T90 at 25°C shows that an almost twofold increase can be achieved by ...
https://arizona.pure.elsevier.com/en/publications/stabilization-of-eptifibatide-by-cosolvents
Course Outline - Drug Stability Studies (Ph.D) - LibGuides at Riphah International UniversityCourse Outline - Drug Stability Studies (Ph.D) - LibGuides at Riphah International University
Revised and expanded by Jens T Carstensen and C T Rhodes. Pharmaceutical photostability and stabilization technology edited by Joseph T Piechocki and Karl Thoma. Modern pharmaceutics by Gilbert S Banker and Christopher T Rhodes. Good manufacturing practices for pharmaceuticals. ...
https://libguides.riphah.edu.pk/c.php?g=455767&p=3114600
DI-045 Drug stability in peritoneal dialysis solutions | European Journal of Hospital PharmacyDI-045 Drug stability in peritoneal dialysis solutions | European Journal of Hospital Pharmacy
Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future ...
https://ejhp.bmj.com/content/21/Suppl_1/A88.2.responses
ICH Guidance in Practice: Validated Stability-Indicating HPLC Method for Simultaneous Determination of Olmesartan Medoximil and...ICH Guidance in Practice: Validated Stability-Indicating HPLC Method for Simultaneous Determination of Olmesartan Medoximil and...
Olmesartan and hydrochlorothiazide were degraded together under different stress test conditions prescribed by International Conference on Harmonization. The samples so generated were used to develop a stability-indicating high performance liquid chromatographic (HPLC) method for the two drugs....
http://www.eurasianjournals.com/ICH-Guidance-in-Practice-Validated-Stability-Indicating-HPLC-Method-for-nSimultaneous,79337,0,2.html
Long-Term Stability of Trimix: A Three-Drug Injection Used to Treat Erectile Dysfunction.Long-Term Stability of Trimix: A Three-Drug Injection Used to Treat Erectile Dysfunction.
Author: Trissel Lawrence A, Zhang Yanping, Year: 2004, Abstract: A three-drug injection mixture of alprostadil 12.5 µg/mL, papaverine hydrochloride 4.5 mg/mL and phentolamine mesylate 0.125 mg/mL in bacteriostatic 0.9% sodium chloride injection was evaluated for stability at 23°C, 4°C, -20°C and -70°C. The injection remained clear and colorless in all samples throughout the study. Chemical stability testing was performed using stability-indicating high-performance liquid chromatographic analysis. Alprostadil was the least stable of the drug components
https://ijpc.com/Abstracts/Abstract.cfm?ABS=1799
Sci. Pharm. | Free Full-Text | Voltammetric Behaviour of Drug Molecules as a Predictor of Metabolic Liabilities | HTMLSci. Pharm. | Free Full-Text | Voltammetric Behaviour of Drug Molecules as a Predictor of Metabolic Liabilities | HTML
Electron transfer plays a vital role in drug metabolism and underlying toxicity mechanisms. Currently, pharmaceutical research relies on pharmacokinetics (PK) and absorption, distribution, metabolism, elimination and toxicity (ADMET) measurements to understand and predict drug reactions in the body. Metabolic stability (and toxicity) prediction in the early phases of the drug discovery and development process is key in identifying a suitable lead compound for optimisation. Voltammetric methods have the potential to overcome the significant barrier of new drug failure rates, by giving insight into phase I metabolism events which can have a direct bearing on the stability and toxicity of the parent drug being dosed. Herein, we report for the first time a data-mining investigation into the voltammetric behaviour of reported drug molecules and their correlation with metabolic stability (indirectly measured via t½), as a potential predictor of drug stability/toxicity in vivo. We observed an inverse
https://www.mdpi.com/2218-0532/88/4/46/htm
Transient Stability Assessment using Neural Networks | Seminar Report and PPT for IT StudentsTransient Stability Assessment using Neural Networks | Seminar Report and PPT for IT Students
Full Details of Transient Stability Assessment using Neural Networks with Free Download of Seminar Report and PPT in PDF and DOC Format with Abstract or Synopsis, Documentation on Advantages and Disadvantages, Base Paper Presentation Slides for IEEE Final Year Information Technology Engineering or IT Students for the year 2015 2016.
http://www.seminarsonly.com/IT/Transient%20%20Stability%20Assessment.php
Michael Hageman | Pharmaceutical ChemistryMichael Hageman | Pharmaceutical Chemistry
Prior to joining the Department of Pharmaceutical Chemistry at The University of Kansas as a Distinguished Professor in 2017, I spent 30+ years working in the Pharmaceutical Industry. I have extensive experience in physicochemical characterization and preclinical assessment of new chemical entities (NCE), including proteins, peptides, oligonucleotides, protein drug conjugates, prodrugs, and other small molecule based therapeutics. I have been directly involved in the Discovery process with chemical lead selection, chemical lead optimization, and drug candidate selection for transition into clinical development. Those preclinical experiences include drug delivery research for both parenteral and oral dosage form design, with particular emphasis on designing specialized formulation strategies to overcome poor drug stability and poor aqueous solubility, with the ultimate goal of enhancing developability and commercialization. I have extensive experience, and resulting patents, on the generation of ...
http://pharmchem.ku.edu/michael-hageman
P - Stability of Drugs - Drug TimesP - Stability of Drugs - Drug Times
Temperature is one of the primary factors affecting drug stability. The rate constant/ temperature relationship has traditionally been described by the Arrhenius equation,. where Ea is the activation energy and A is the frequency factor. This equation is a variant of the equation describing the effect of temperature on equilibrium processes that was developed by vant Hoff in 1887. Arrhenius applied his equation to various reaction processes.298 Comparison of the empirical Arrhenius equation to the Eyring equation, Eq. (2.7), shows some similarities and some differences. The frequency factor A in the Arrhenius equation corresponds to the product of the universal collision and entropy terms in Eq. (2.7) while the Ea term in Eq. (2.70) is related to the enthalpy term in Eq. (2.7).299 Because aplot of the logarithm of k against the reciprocal of absolute temperature generally yields a linear relationship (Arrhenius plots), the frequency factor and activation energy are regarded as independent of ...
https://www.drugtimes.org/stability/p.html
Technology - Improved pDMI Inhaler Formulations
Novel biodegradable, non-toxic nanoparticles that act as stabilizing excipients with a wide variety of suspension drug candidates including polar & non-polar drug particles, bio-macromolecules (proteins/peptides), gene therapies (DNA/siRNA) as well as amorphous and crystalline therapeutics have been developed which provide a platform for improving insoluble drug delivery. A large variety of approaches have been developed at WSU aimed at increasing the effectiveness of pressurized meter-dose inhalers (pMDIs) through improved aerosol characteristics, drug stability and reduced biotoxicity. Dr. Sandro da Rocha has been researching novel oral inhalation formulations and methods relevant in numerous pulmonary drug delivery markets including asthma, COPD, and lung cancer. Novel nanoparticle-based drug compositions have been shown to greatly improve and expand therapeutic drug delivery to the lungs through pressurized meter-dose inhalers (pMDIs). Some of these technologies can also be applied to dry ...
http://wayne.technologypublisher.com/technology/5129
Question name one physicochemical property influencing drug absorptionQuestion name one physicochemical property influencing drug absorption
hello leela...... the physicochemical factors affecting drug absorption are. drug solubility and dissolution. particle siza and surface area. polymorphism and amorphism. pseudopolymorphism. salt form of the drug lipophilicity of drug. pka and pH value. drug stability. reference: brahmankar, page no.18 edition 1995. ...
http://pharmainfo.net/answers/pharmaceutics/name-one-physicochemical-property-influencing-drug-absorption
Longitudinal Stability Evaluation of Biomarkers and Their Correlation in Cerebrospinal Fluid and Plasma from Patients with...Longitudinal Stability Evaluation of Biomarkers and Their Correlation in Cerebrospinal Fluid and Plasma from Patients with...
There is an increasing demand for biomarkers in clinical treatment trials to demonstrate target engagement and to support disease modification claims. To be able to detect treatment related effects, a prerequisite is that the levels of the biomarker are stable over time or that the change over time is known. In the present study, the stability of alpha- and beta-cleaved soluble amyloid-beta protein precursor (sA beta PP alpha and sA beta PP beta), A beta(1-40) together with the phosphorylated form of neurofilament heavy/medium (pNfH/M) in cerebrospinal fluid (CSF) was analyzed in a cohort of 51 patients with Alzheimers disease. In addition, the stability of A beta(1-40), beta(1-42), and sA beta PP beta in plasma was explored. Plasma and CSF was sampled at baseline and after 6-months follow up, and all patients were on stable treatment with acetylcholinesterase inhibitors. During this 6-month longitudinal follow-up, we saw a small, but consistent and statistically significant increase in CSF ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:582575
Stability data
Updated 30.10.2018. The bias criteria is based on biological variation within and between individuals. If the percentage difference in component level between fresh and long term stored samples does not exceed the allowed bias, one may report the difference as negligible.. With new technology, the Janus material can be used in genetic studies. It has been demonstrated that the miRNA and DNA found in the samples are of sufficient quality to perform sequencing analyses. ...
https://www.kreftregisteret.no/en/Research/Janus-Serum-Bank/Quality-assurance/Stability-data/
Chemical Violet Cobalt Isocaprylate with Fast Drier Speed And Good Stability BNK-A01 - good quality Cobalt Water for sale
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http://bnkchemical-com.wiztong.cn/china-chemical_violet_cobalt_isocaprylate_with_fast_drier_speed_and_good_stability_bnk_a01-pa27579.html
Determination and integration of abundance, processing efficiency, and degradation kinetics of the mRNAs encoding all T. brucei...Determination and integration of abundance, processing efficiency, and degradation kinetics of the mRNAs encoding all T. brucei...
Since over 40 enzymes will be investigated for their mRNA abundance, processing, and degradation kinetics, the less tedious and more accurate Next Generation Sequencing of the entire mRNA repertoire of the cell is employed. To optimise the proportion of useful sequence, while including RNA fragments that are products of of degradation, rRNA is depleted using the eukaryotic Ribominus kit (Ambion). Two biological replicates are treated with Sinefungin and Actinomycin D to inhibit RNA processing and transcription, for different time periods. RNA is collected before treatment, 5 min after the addition of Sinefungin, 5 min after addition of ActD (+Sin), then 10 min after, 20, 30, 60 and 120 min. The samples are sequenced using the Illumina standard protocol, and the sequenced reads are aligned to the reference genome TREU927, and the number of reads aligned to each ORF are determined. ...
https://fairdomhub.org/studies/76
Preformulation studies of ceftriaxone for pediatric non-parenteral administration as an alternative to existing injectable...Preformulation studies of ceftriaxone for pediatric non-parenteral administration as an alternative to existing injectable...
We use cookies to ensure that we give you the best experience on our website. If you click Continue well assume that you are happy to receive all cookies and you wont see this message again. Click Find out more for information on how to change your cookie settings ...
https://www.tropmedres.ac/publications/908135
Avactas Optim® 1000 Helps De-risk Preformulation StudiesAvactas Optim® 1000 Helps De-risk Preformulation Studies
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.
https://www.technologynetworks.com/tn/product-news/avactas-optim-1000-helps-derisk-preformulation-studies-215807
The Financial Stability Assessment Framework of the IMF: Experience in Europe, Keynote Address by Mr. Takatoshi Kato, Deputy...The Financial Stability Assessment Framework of the IMF: Experience in Europe, Keynote Address by Mr. Takatoshi Kato, Deputy...
As prepared for delivery Governor Liebscher, distinguished guests, ladies and gentlemen, good morning to you all. It is a great pleasure for me to be here with you today, at the 33rd Economics Conference hosted by the Austrian National Bank-and, I must add, it is a delight to visit again this beautiful and historic city. I have been asked by the conference organizers to speak to the issue of financial sector stability and the IMFs work in this area-and I will seek to stay close to this topic in my remarks.. Financial sector stability has been described as the issue that central bankers worry about when they are not worrying about price stability. Experience regularly reminds us that there is a solid basis for this worry. The East Asian crisis during the late 1990s provided a striking example of how financial sector weaknesses can trigger economic turmoil and amplify the effects of adverse shocks on the economy, with severe economic and social consequences. Several industrial countries, ...
https://www.imf.org/en/News/Articles/2015/09/28/04/53/sp051205
virtualbox.org • View topic - Status: VirtualBox Wide-Scale Stability Test Matrix v4.1.6 !
Technologov: Great work, very comprehensive. I am wondering if the table can be recreated in the virtualbox wiki using restructured text? This might be a good place for people to collaborate on updating it as things change. I couldnt find any software to do it automatically (although twiki has a plugin to import excel spreadsheets). I dont really know enough about restructured text (I know it can do tables) but it must be possible, no ...
https://forums.virtualbox.org/viewtopic.php?p=115127
CSIR - Centre for Cellular & Molecular Biology
CCMB maintains and stocks about 6500 biochemicals for the ongoing research activities of the laboratory. The facility has a cold room (+4°C), two +4°C refrigerators, eight deep freezers (-20°C) and two ultra deep freezers (-70°C) for storage of chemicals as per the recommended storage conditions. However, the chemicals stable at room temperature are kept in a room (98 sq.mtrs plinth area) where temperature is maintained at 28°C. The stocks of fine biochemicals include amino acids, proteins, enzymes, purification kits and buffer reagents. In addition, stocks of restriction enzymes, immunology research kits for purification and detection of recombinant proteins, reagents for protein electrophoresis, PCR, RTPCR, DNA sequencing and synthesis and buffers, tissue culture ware, medium and medium supplements, gel electrophoresis and column chromatography materials, chemicals related to proteomics, and microarray analysis are also kept in the centralized facility. The requirement for these chemicals ...
http://www.ccmb.res.in/index.php?view=finebiochem&mid=155&id=48
Université Francois Rabelais - Tours - In Vitro Characterization and Stability Profiles of Antibody-Fluorophore Conjugates...
Fluorescent labelling of monoclonal antibodies (mAbs) is classically performed by chemical bioconjugation methods. The most frequent labelling technique to generate antibody-fluorophore conjugates (AFCs) involves the bioconjugation onto the mAb lysines of a dye bearing an N-hydroxysuccinimide ester or an isothiocyanate group. However, discrepancies between labelling experiments or kits can be observed, related to reproducibility issues, alteration of antigen binding, or mAb properties. The lack of information on labelling kits and the incomplete characterization of the obtained labelled mAbs largely contribute to these issues. In this work, we generated eight AFCs through either lysine or interchain cysteine cross-linking bioconjugation of green-emitting fluorophores (fluorescein or BODIPY) onto either trastuzumab or rituximab. This strategy allowed us to study the influence of fluorophore solubility, bioconjugation technology, and antibody nature on two known labelling procedures. The structures of
https://hal-univ-tours.archives-ouvertes.fr/hal-02425275
L Arginine Solution Stability Sex Pills For Men Aknt KnuL Arginine Solution Stability Sex Pills For Men Aknt Knu
The icariin acts expand the capacities of the corpus cavernosum and its blood vessels, allowing more blood to flowresulting in a firmer, harder erection. Even the boss of his company dares to slander, is the advantage really so easy to take? Park Zhixie rubbed his stomach and walked to the window The past few days were really tiring Just as he sighed and prepared to adjust his mood to meet the next challenge, the phone rang Jiyeon is gone. Zheng Xiujing said angrily So Erectile Dysfunction Names let you watch Park Jiyan shouted Erectile aggressively Zheng Xiujing rolled her eyes directly, and some doubts appeared in her heart Kim Dysfunction Taehee showed his favor Names to Park Jiyeon on the first day he joined the company, there is a problem! Big problem Unless. With countless male enhancement supplements available on the market today it seems impossible to find the right one Sexual performance declines naturally as men age, which may contribute to feelings of inadequacy or embarrassment. ...
http://aknt.knu.edu.ua/Penis-Enlargement-Online/Aab6e69db_L-Arginine-Solution-Stability
Stability profile by minimizing wall effects for a personal care composition comprising at least two phases - Niebauer, Michael...Stability profile by minimizing wall effects for a personal care composition comprising at least two phases - Niebauer, Michael...
A personal care product including a container having an inner wall and a personal care composition positioned within the container, the personal care composition including at least two phases, wherein
https://www.freepatentsonline.com/y2007/0010410.html
5/2016 - GenomeWeb5/2016 - GenomeWeb
May 13, 2016. SeraCare Life Sciences has launched AccuPlex Zika Reference Material, which is designed to fast track the development and validation of PCR-based Zika virus assays. The reference material is a recombinant virus product and it contains the entire RNA genome of the ZIKV 2007 strain in four separate overlapping virus constructs. The AccuPlex recombinant viruses are stable at room temperature for at least 20 months and at 4° C for at least two years. ...
https://www.seracare.com/news-events/news/new-products_genomeweb/
CF® Dye Dextran 150,000 MW, Anionic and Fixable | BiotiumCF® Dye Dextran 150,000 MW, Anionic and Fixable | Biotium
Most of our products are stable at room temperature for many days, so in all likelihood the product will still work just fine. To be on the safe side, we recommend performing a small scale positive control experiment to confirm that the product still works for your application before processing a large number of samples or precious samples.. One exception that we are aware of is GelGreen™, which is more sensitive to light exposure than most of our other fluorescent dyes. If GelGreen™ is exposed to ambient light for a prolonged period of time (days to weeks), its color will change from dark orange to brick red. If this occurs, the GelGreen will no longer work for gel staining.. ...
https://biotium.com/product/cf-dye-dextran-150000-mw-anionic-and-fixable/
Riddled: But all that doesnt anti-matter Now we found ourselves a black hole in spaceRiddled: But all that doesnt anti-matter Now we found ourselves a black hole in space
What Chirumbolo et al. are proposing is that a histamine molecule in water can cause the water molecules to arrange themselves around it in a kind of quasi-crystalline cluster -- a cluster having the same chemical and biological properties as the histamine itself. Further, the clusters are self-replicating: they can catalyse the formation of copies of themselves across multiple stages of dilution and succussion. This is a whole new polymorph of H2O, more stable at room temperature than liquid water ...
http://eusa-riddled.blogspot.com/2012/05/but-all-that-doesnt-anti-matter-now-we.html
HGH Fragment 176-191 2mg - HKYCGCHGH Fragment 176-191 2mg - HKYCGC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.. HGH Frag 176-191 is a fragment of the HGH peptide. Scientists found that if they truncated the peptide at the C terminal region they could isolate the fat loss attributes associated with HGH. Taking this fragment from HGH, including the peptide bonds from 176-191, they found they had developed a peptide that regulated fat loss 12.5 times better than regular HGH.. Introduction:. There is no question as to why bodybuilders of the modern era utilize human growth hormone. Its ability to regulate fat loss, pack on size and increase IGF-1 levels is just a few of the many attributes that many seek. HGH Frag 171-191 was developed so that bodybuilders and athletes not looking for the growth properties from HGH could still reap all the results of its amazing fat loss ...
https://www.legit-steroid-powder.com/portfolio-item/hgh-fragment-176-191-2mg/
GHRP-6 5mg - PuritysourcelabsGHRP-6 5mg - Puritysourcelabs
Supplier: Euro-PharmaciesPurity: 98.22%Appearance: White PowderUnit Size: 5 mg/vialUnit Quantity: 1 VialBatch No.: EP-0325B2Synonyms: GHRP-6 AcetateStorage: Lyophilized Fragment GHRP-6 is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting GHRP-6 should be refrigerated at temperatures not to exceed 36 F. Shipping from Europe
http://puritysourcelabs.ru/peptides/616-ghrp-6-5mg.html
Simple Accordion with CSS & jQuery by Soh Tanaka
The reaction is believed to proceed by the indicated conversion of a lithium carboxylate to the dilithium salt18 which is stable at room temperature in the absence of proton-donating solvents or reactants. However, the rapidity with which this dilithium salt is decomposed to a ketone in the presence of proton donors, accompanied by the rapidity of the subsequent reaction of the ketone with more methyllithium, can lead to a common side reaction in which an alkyldimethyl carbinol is formed. Both of the aforementioned reactions appear to be fast compared with 0.01 second usually required to disperse components with the conventional mixing techniques. This side reaction can be almost entirely avoided by taking precautions to minimize the possibility that high local concentrations of the geminal dialkoxide and the lithium reagent are present when a proton donor is added during either the reaction or the subsequent quenching. It is frequently possible to obtain only relatively small amounts of the ...
http://www.orgsyn.org/demo.aspx?prep=CV5P0775
Cloning and Mutagensis Sample Submission Guidelines - Resources - GENEWIZCloning and Mutagensis Sample Submission Guidelines - Resources - GENEWIZ
Starting material that is stable at room temperature may be submitted via a GENEWIZ Drop Box (when available). A print out of the online ORDER SUMMARY page must be included with the material. Contact [email protected] to request a Drop Box pick-up for your location or if you have any Drop Box questions. ...
https://www.genewiz.com/en/Public/Resources/Sample-Submission-Guidelines/Cloning-and-Mutagenesis-Sample-Submission-Guidelines
Fos A Dophilus | Live Bacteria | Dairy Free | CytoplanFos A Dophilus | Live Bacteria | Dairy Free | Cytoplan
Cytoplan Fos-A-Dophilus contains six strains of live native bacteria. Recommended for people over 40. Stable at room temperature - no need to refrigerate.
https://www.cytoplan.co.uk/cognitive/fos-a-dophilus-probiotic-supplement
Swiss Meringue Buttercream Recipe | BraveTart | Serious EatsSwiss Meringue Buttercream Recipe | BraveTart | Serious Eats
This light and silky buttercream is none too sweet, and beautifully stable at room temperature. The finished product can be customized with a splash of extract, a drizzle of melted chocolate, concentrated fruit purées, or just about whatever you crave.
https://www.seriouseats.com/recipes/2017/05/swiss-meringue-buttercream-frosting-recipe.html
Accelerated Stability Modeling for Peptides: a Case Study with Bacitracin | SpringerLinkAccelerated Stability Modeling for Peptides: a Case Study with Bacitracin | SpringerLink
The Accelerated Stability Assessment Program (ASAP) was applied for the first time to a peptide, the antibiotic active pharmaceutical ingredient bacitracin
https://link.springer.com/article/10.1208/s12249-016-0635-7?error=cookies_not_supported&code=b6bfe08f-4105-4739-be52-0aaae17f34a1
Archive - Loock Laser LabArchive - Loock Laser Lab
Although traditional 3D fluorescence spectroscopy is a powerful analytical technique, it is also notoriously slow, making it inappropriate for kinetic studies. Our paper presents a much faster way to collect 3D fluorescence measurements, using Hadamard barcodes to encode a white light source and the corresponding fluorescence signal. In this work, we used a submersible fiber-probe to measure both the degradation kinetics of spinach extract in acid, and the thermal degradation kinetics of rhodamine B.. Read More ...
http://www.loocklaserlab.com/home-page
Next pageNext page
Hey spearhead as rams said go for the Ford iKOn TDCi. its the diesel josh machine in a new avatar..its got a superbly efficient, fabulously torquey 1.4 engine that can make many diesel sedans twice its price run for cover. i have test driven the vehicle and di some spirited driving.. its got a superb chassis and very good stability at speeds above 100kmph but engine noise filters into the cabin. becoz the main fact is Ford is giving the 1.4TDCi engine from the Fiesta at Rs 1.80 lakhs chepear in the iKOn. for that reason it isnt perfectly refined but overall its a superb vfm package. recent price hike is a mere Rs 7000 to 8000 hike over the existing ex showroom price of Rs 5.19 lakhs. like within Rs 6 lakhs budget you will get a swift dzire LDi and it has only power steering and a/c but Ford IKon at this price is fully loaded with power steering, a/c, powerwindows( fr/rr), central locking, Mp3 player,the best rear seat in its class, lovely beige interiors which gives the impression that the car ...
https://forum.autocarindia.com/topic/3362-ford-new-ikon-14-tdci/page/3/
One Turn at a Time | Outside BozemanOne Turn at a Time | Outside Bozeman
Nailing the powder shot. Two feet of fresh powder? Check. Bluebird? Check. Directional morning light? Check. A protected slope with good stability and minimal objective hazards? Check. Its go time.
http://outsidebozeman.com/magazine/archives/winter-2017-18/one-turn-time
Determinants of disparities between perceived and physiological risk of falling among elderly people: cohort study | The BMJ
About 10% of the study population showed excessive levels of perceived fall risk and were classified as anxious. Despite their low physiological fall risk, almost 40% of the anxious group experienced multiple or injurious falls during the one year follow-up. In keeping with previous studies, we anticipated that self imposed restriction on levels of physical activity would contribute to overall risk in this group.5 13 However, there was no indication of lower levels of activity, so other reasons need to be explored as to why anxious participants fell more than vigorous participants during follow-up.. It is possible that the anxious group had a residual physiological fall risk not encompassed by the physiological profile assessment. Thus, although the groups low physiological profile assessment score indicated that the integrity of individual sensorimotor components was adequate, their relatively poor performance on the coordinated stability test suggests that the integration of each of these ...
https://www.bmj.com/content/341/bmj.c4165.full.pdf+html
Harikrushna TechnoprideHarikrushna Technopride
Ideal For Short Runs, Stability Test Or Clinical Trial Batches, This Filling Machine Can Be Used On A Bench Top Or In A Clean Air Hood ...
http://www.harikrushnatechnopride.com/uniject-filling-n-closing-system.html
accel stability modeling for peptides. bacitracin | FreeThink Technologies
In addition to producing and licensing ASAPprime®, the leading stability software package for determining shelf life under highly accelerated conditions, FreeThinks pharma laboratories help companies solve even the most complex problems with a particular emphasis on issues related to stability testing (shelf life). FreeThink scientists are experts at developing stability-indicating methods, determining shelf lives, developing formulations for complex needs, and determining packaging.. ...
https://freethinktech.com/freethink-posters/attachment/accel-stability-modeling-for-peptides-bacitracin/
activ-blister | FreeThink Technologies
In addition to producing and licensing ASAPprime®, the leading stability software package for determining shelf life under highly accelerated conditions, FreeThinks pharma laboratories help companies solve even the most complex problems with a particular emphasis on issues related to stability testing (shelf life). FreeThink scientists are experts at developing stability-indicating methods, determining shelf lives, developing formulations for complex needs, and determining packaging.. ...
https://freethinktech.com/freethink-white-papers/attachment/activ-blister/
HISTORIC LABOUR DEAL BRINGS LONG-TERM STABILITY TO ASIA PACIFIC GATEWAY - PDFHISTORIC LABOUR DEAL BRINGS LONG-TERM STABILITY TO ASIA PACIFIC GATEWAY - PDF
the official publication of T H E A S S O C I A T I O N O F C A N A D I A N P O R T A U T H O R I T I E S CANADIAN PORTS HISTORIC LABOUR DEAL BRINGS LONG-TERM STABILITY TO ASIA PACIFIC GATEWAY Improving
http://docplayer.fr/1018670-Historic-labour-deal-brings-long-term-stability-to-asia-pacific-gateway.html
Hepatocyte, S9, or Microsomal Stability Screening | SEKISUI XenoTechHepatocyte, S9, or Microsomal Stability Screening | SEKISUI XenoTech
Learn how our metabolic stability screening services assess a drugs microsomal stability (or in hepatocytes) providing insight to clearance.
https://www.xenotech.com/preclinical-drug-development/in-vitro-studies/adme-screening/metabolic-stability/
Multidimensional stability of planar traveling waves for an integrodifference modelMultidimensional stability of planar traveling waves for an integrodifference model
This paper studies the multidimensional stability of planar traveling waves for integrodifference equations. It is proved that for a Gaussian dispersal kernel, if the traveling wave is exponentially orbitally stable in one space dimension, then the corresponding planar wave is stable in $H^m(\mathbb{R}^N)$, $N\ge 4$, $m\ge [N/2]+1$, with the perturbation decaying at algebraic rate.
https://www.aimsciences.org/article/doi/10.3934/dcdsb.2013.18.741
Producten - Producten en instrumentarium voor oogheelkundige specialisten - Rockmed B.V.Producten - Producten en instrumentarium voor oogheelkundige specialisten - Rockmed B.V.
High stability (median rotation 1.54°) 100% of the implanted lenses had ≤ 5° rotation from end of surgery to 4 - 6 months ...
http://www.rockmed.nl/NL/producten/115-cataract/124-intra-oculaire-lenzen/476-torische-iol/343-hoya-vivinex-toric-xy1a
THE NATIONAL HOME INFUSION ASSOCIATION: Infusion Magazine - ArchivesTHE NATIONAL HOME INFUSION ASSOCIATION: Infusion Magazine - Archives
Chamallas SN, Fishwick J, Riesenberg M. Special delivery: Keeping the product stable during shipping. 1997;4(3):30-2. Choy GS, Egging P, White B. Stability data for ambulatory infusion pump reservoirs. 1998;4(11):18-23. Fagerman K. 4-Chamber total parenteral nutrition system: A needleless total nutrient admixture. 1997;3(12):15-9 Henderson ML. Drug stability and compatibility: A review. 1995;1(12):33-36. Iltz J. Thinking inside the box: Do compounded sterile preparations maintain refrigerated conditions during transit? 2013;19(2):39-44. Kastango E. USP chapter ,797,: The next phase. 2006. 12(4):25-9. Lima HA. Drug stability and compatibility. 1996;2(11):10-16. Panella-Spangler P. New drug review for 2001;7(5):14-7. Nowobilski-Vasilios A and Bing C. Beyond-use dating of compounded sterile preparations-Effectively mapping out the complexities for better decision making. 2013;19(6):37-45 ...
http://www.nhia.org/infusion/archives/drug.cfm
Encapsulation of β-sitosterol plus γ-oryzanol in O/W emulsions: formulation characteristics and stability evaluation with...Encapsulation of β-sitosterol plus γ-oryzanol in O/W emulsions: formulation characteristics and stability evaluation with...
Khalid, Nauman, Kobayashi, Isao, Neves, Marcos A., Uemura, Kunihiko, Nakajima, Mitsutoshi and Nabetani, Hiroshi 2017, Encapsulation of β-sitosterol plus γ-oryzanol in O/W emulsions: formulation characteristics and stability evaluation with microchannel emulsification, Food and bioproducts processing, vol. 102, pp. 222-232, doi: 10.1016/j.fbp.2017.01.002. ...
http://dro.deakin.edu.au/view/DU:30092169
Stability of Cefotaxime Sodium After Reconstitution in 0.9% Sodium Chloride Injection and Storage in Polypropylene Syringes for...Stability of Cefotaxime Sodium After Reconstitution in 0.9% Sodium Chloride Injection and Storage in Polypropylene Syringes for...
Author: Gupta Vishnu D, Year: 2002, Abstract: A stability-indicating high-performance liquid chromatographic assay method was used to study the stability of cefotaxime sodium (50 mg/mL) in 0.9% sodium chloride injection in polypropylene syringes at 5°C and 25°C. The concentrations of the drug were directly related to peak heights, and the percent relative standard deviation based on 5 injections was 1.1. There were at least three products of decomposition that separated from the intact drug. At 5°C, the decomposition was less than 3%
https://ijpc.com/abstracts/abstract.cfm?ABS=1048
Stability-indicating HPTLC determination of imatinib mesylate in bulk drug and pharmaceutical dosage</em>...
TY - BOOK. T1 - Stability-indicating HPTLC determination of imatinib mesylate in bulk drug and pharmaceutical dosage. AU - Musmade, P.. AU - Vadera, N.. AU - Subramanian, G.. N1 - cited By 0. PY - 2011. Y1 - 2011. U2 - 10.1007/978-3-642-14025-9_6. DO - 10.1007/978-3-642-14025-9_6. M3 - Book. BT - Stability-indicating HPTLC determination of imatinib mesylate in bulk drug and pharmaceutical dosage. ER - ...
https://manipal.pure.elsevier.com/en/publications/stability-indicating-hptlc-determination-of-imatinib-mesylate-in-
ISO 105-Z08 : Textiles - Tests for Colour Fastness Part Z08: Determination of Solubility and Solution Stability of Reactive...ISO 105-Z08 : Textiles - Tests for Colour Fastness Part Z08: Determination of Solubility and Solution Stability of Reactive...
ISO 105-Z08 : Textiles - Tests for Colour Fastness Part Z08: Determination of Solubility and Solution Stability of Reactive Dyes in the Presence of Electrolytes
https://global.ihs.com/doc_detail.cfm?document_name=ISO%20105-Z08&item_s_key=00225825
Items where Research Area is Chemistry - Kingston University Research RepositoryItems where Research Area is Chemistry - Kingston University Research Repository
Sabagh, B. and Foot, P.J.S. (2009) Synthesis of novel donor-acceptor polymer blends and their properties. Polymers and Polymer Composites, 17(9), pp. 529-533. ISSN (print) 0967-3911 Sabagh, Basseem (2007) Intrinsically conducting polymers. (PhD thesis), Kingston University. Salman, Dahlia, Swinden, Julian, Peron, Jean-Marie R., Barton, Stephen and Nabhani-Gebara, Shereen (2016) New investigations into the stability of Mesna using LC-MS/MS and NMR. Expert review of anticancer therapy, 16(1), pp. 123-130. ISSN (print) 1473-7140 Salman, Dahlia, Swinden, Julian, Barton, Stephen, Peron, Jean-Marie R. and Nabhani-Gebara, Shereen (2014) Improving drug stability to promote home cancer therapy. Hospital Pharmacy Europe(72), pp. 38-40. Sam, C, Alhakem, H and Freestone, N.S. (2013) [Beta]-Adrenergic subtypes in chick embryonic cardiac myocytes. Proceedings of the 6th European Congress of Pharmacology, pp. 63-66. Sam, C.L.S., Bolton, T.B., Piper, I.T., Greenhill, D and Freestone, N.S. (2013) A novel ...
http://eprints.kingston.ac.uk/view/subjects/chemistry.html
METHIMAZOLE 2.5 MG/ML ORAL SUSPENSIONMETHIMAZOLE 2.5 MG/ML ORAL SUSPENSION
​Golden Gate Veterinary Pharmacists have an acute awareness of drug stability in various forms. In many cases certain species of animals are only capable of taking liquid medications.
https://ggvcp.pharmacy/store/new-patient-rx/methimazole-2.5-mg-ml-oral-suspension/
Patente US6689932 - Absorbent articles with simplified compositions having good stability - Google PatentesPatente US6689932 - Absorbent articles with simplified compositions having good stability - Google Patentes
The present invention relates to absorbent articles including skin care compositions. The skin care compositions of the invention are stable on the bodyside liners of absorbent articles despite not containing an immobilizing agent. Surprisingly, the skin care compositions of the invention even demonstrate less migration away from the bodyside liner than do other compositions that contain so-called
http://www.google.es/patents/US6689932?dq=flatulence
Stable Molecular Weight Red Purple Cobalt Chloride Water with Fast Drier Speed and Good Stability BNK-A22 - good quality Cobalt...
script language=javascript type=text/javascript src=http://js.users.51.la/18710558.js,,/script, ,noscript,,a href=http://www.51.la/?18710558 target=_blank,,img alt=我要啦免费统计 src=http://img.users.51.la/18710558.asp style=border:none /,,/a,,/noscript, ,script, (function(i,s,o,g,r,a,m){i[GoogleAnalyticsObject]=r;i[r]=i[r],,function(){ (i[r].q=i[r].q,,[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,script,https://www.google-analytics.com/analytics.js,ga); ga(create, UA-85987657-6, auto); ga(send, pageview); ,/script ...
http://bnkchemical-com.wiztong.cn/china-stable_molecular_weight_red_purple_cobalt_chloride_water_with_fast_drier_speed_and_good_stability_bnk_a22-pa27584.html
Advanced oxidation degradation kinetics as a function of ultraviolet LED duty cycle on Environmental XPRTAdvanced oxidation degradation kinetics as a function of ultraviolet LED duty cycle on Environmental XPRT
Article Advanced oxidation degradation kinetics as a function of ultraviolet LED duty cycle. Ultraviolet (UV) light emitting diodes (LEDs) may be a viable option as a UV light source for advanced oxidation processes (AOPs) utilizing photocatalysts or...
https://www.environmental-expert.com/articles/advanced-oxidation-degradation-kinetics-as-a-function-of-ultraviolet-led-duty-cycle-483687
Cytotoxicity and in Vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents...Cytotoxicity and in Vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents...
Cytotoxicity and in Vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents -
https://scite.ai/reports/cytotoxicity-and-in-vitro-degradation-8GD4anbm
Product Related Impurities and Degradants Analysis | Life Sciences | SGS AustraliaProduct Related Impurities and Degradants Analysis | Life Sciences | SGS Australia
Product-Related Impurities and Degradants Analyses from SGS - essential product-related impurities analysis in biopharmaceutical products. Learn more.
https://www.sgs.com.au/en-gb/life-sciences/contract-laboratory-services/analysis-of-impurities-and-contaminants/product-related-impurities-and-degradants-analysis
Genetic stability assessment of Taraxacum pieninicum plantlets after long-term slow growth storage using ISSR and SCoT markers ...Genetic stability assessment of Taraxacum pieninicum plantlets after long-term slow growth storage using ISSR and SCoT markers ...
Genetic stability is highly important in terms of endangered species gene banks. Culture and cold stresses under in vitro conditions may lead to genetic variability. Many methods and possibilities to...
https://link.springer.com/article/10.2478%2Fs11756-019-00377-x
Serum Amyloid A | eClinpathSerum Amyloid A | eClinpath
Previous studies have shown that equine SAA is more stable at room temperature than refrigerated. A small study at Cornell University confirmed this finding. Two equine samples with high values of 481 and 177 ug/ml showed a 2-3% decrease in concentration at 4ºC with storage for 24 hours versus a 3-5% decrease at room temperature. With storage for 72 hours, the drop at 4ºC was greater than at room temperature (7% versus 3-6% at 48 hours and 8-9% versus 2-4% at 72 hours). Very high values (,60 ug/dL) were still abnormal after 10 days of storage at either temperature (Hillstrom et al 2010). SAA concentrations are stable frozen (-20ºC), thus it is recommended that for storage ,24 hours, the samples should be frozen and shipped ensuring that they remain frozen. If freezing is not an option, then the samples should be maintained at room temperature. This also suggests that mildly increased concentrations may drop to within reference intervals (,20 ug/mL in horses) with storage. Stability is unknown ...
http://eclinpath.com/chemistry/proteins/acute-phase-proteins/serum-amyloid/
Scrambled AAV siRNA Control Virus (Serotype 3)
AAV Viruses are stable at room temperature for short term storage and are shipped with gel ice packs. Do not store at -20°C or 4°C for long term. For long term storage, it is recommended to store the viruses at -80°C and avoid repeated freeze-thaw cycles. Before storing at -80°C, it is advisable to make small aliquots to avoid repeated freeze-thaw cycles. ...
https://www.abmgood.com/scrambled-aav-sirna-control-virus-serotype-3-iaav01503.html
Scrambled AAV siRNA Control Virus (Serotype 4)
AAV Viruses are stable at room temperature for short term storage and are shipped with gel ice packs. Do not store at -20°C or 4°C for long term. For long term storage, it is recommended to store the viruses at -80°C and avoid repeated freeze-thaw cycles. Before storing at -80°C, it is advisable to make small aliquots to avoid repeated freeze-thaw cycles. ...
https://www.abmgood.com/scrambled-aav-sirna-control-virus-serotype-4-iaav01504.html
ActoFactor™ Recombinant Human Interleukin 12 (HEK) | Creative BioarrayActoFactor™ Recombinant Human Interleukin 12 (HEK) | Creative Bioarray
The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rHu IL-12 should be stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles ...
https://www.creative-bioarray.com/ActoFactor-Recombinant-Human-Interleukin-12-HEK-CSC-CTK0247-item-3573.htm
VEGF-165, mouse, recombinant (E. coli) | PromoCellVEGF-165, mouse, recombinant (E. coli) | PromoCell
The lyophilized rMu VEGF, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rMu VEGF should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.10% endotoxin-free HSA or BSA; e.g. Cat.No. C-69500A). Avoid repeated freeze / thaw cycles ...
https://promocell.com/product/vegf-165-mouse-recombinant-e-coli/
ATP7A Whole Gene Sequencing | Genetic Testing Lab | DNA Analysis | DDC Clinic Laboratory
Blood samples are stable at room temperature (15ºC to 25ºC) for one day or at 2º to 8ºC for up to 5 days. Blood samples should not be frozen at any time.. DNA sample stability is dependent on the methodology used for the isolation. In general the DNA should be stable and can be shipped ambient or cold, following the directions below.. Specimens from outside facilities should be packaged according to standard medical safety practices. Refrigerate samples if stored overnight prior to shipping. In hot weather, include a cool pack in the shipping container. Do not allow the specimen to freeze at any time. Package the completed test requisition inside the packaging container with the specimen. Please ship by overnight priority.. Specimens should not be shipped on Fridays, Saturdays or the day preceding a holiday.. **Holiday schedules will be noted on our website at least one week prior to the holiday. Feel free to contact us with any questions.. ...
https://www.ddccliniclab.org/test/detail/atp7a-whole-gene-sequencing
MLC1 Whole Gene Sequencing | Genetic Testing Lab | DNA Analysis | DDC Clinic Laboratory
Blood samples are stable at room temperature (15ºC to 25ºC) for one day or at 2º to 8ºC for up to 5 days. Blood samples should not be frozen at any time.. DNA sample stability is dependent on the methodology used for the isolation. In general the DNA should be stable and can be shipped ambient or cold, following the directions below.. Specimens from outside facilities should be packaged according to standard medical safety practices. Refrigerate samples if stored overnight prior to shipping. In hot weather, include a cool pack in the shipping container. Do not allow the specimen to freeze at any time. Package the completed test requisition inside the packaging container with the specimen. Please ship by overnight priority.. Specimens should not be shipped on Fridays, Saturdays or the day preceding a holiday.. **Holiday schedules will be noted on our website at least one week prior to the holiday. Feel free to contact us with any questions.. ...
https://www.ddccliniclab.org/test/detail/mlc1-whole-gene-sequencing
OPAT outcomes and reasons for failure to completeOPAT outcomes and reasons for failure to complete
OPAT is used for treating a wide range of infections, including skin and soft tissue infections, osteoarticular infections, bacteraemia, endocarditis and complex intra-abdominal and urinary tract infections, even in presence of multiresistant microorganisms. Correct choice of antimicrobial agent and adequate patient selection are crucial for reaching therapeutic success and avoiding readmissions, treatment prolongation or treatment-related toxicity. The optimal antimicrobial for OPAT must be highly effective, have a long half-life and an adequate spectrum of action. Ceftriaxone and teicoplanin are currently the most prescribed antibiotics for OPAT, though daptomycin and ertapenem are also on the rise, due to their high efficiency, safety and wide spectrum of action. Antibiotics that are stable at room temperature can be administered through a continuous perfusion, though self-administration is preferable although it requires training of the patient or the caregiver. Factors that are most ...
http://www.ivteam.com/intravenous-literature/opat-outcomes-reasons-failure-complete/
Exelon drug price | 01111069 CHUSNUL CHOTIMAH
memantine is on the ccf formulary of accepted drugs, along with 3 of the 4 fda-approved ache Buy inhibitors, donepezil aricept , galantamine reminyl , and rivastigmine exelon .. Ebulliently cthulhu despondencies are a christingles. Dressage is leased. Kantian sashall sanely perfuse. Criss - cross applesauce supreme shalstone has nextdoor taken in online asunder unlike the substantially liquorish waypoint.. when exelon oral solution is combined with cold fruit juice or soda, online the mixture is stable at room temperature for up to 4 hours.. Motivated compellers were the Tadapox performers. Furlong was the precedency.. if the merger Pills is approved, exelon expects it to close in the second or third quarter of 2015.. Sumptuously whiny insensibility orients. Communistically statured Zyrtec will have included until the totally taciturn mercedes. Katheryn was the jutta. Samp has captiously deigned.. ...
http://cuzndog.mhs.narotama.ac.id/2018/02/01/exelon-drug-price/
Carbons new champion: Rice U. theorists calculate atom-thick carbyne chains may be strongest material everCarbons new champion: Rice U. theorists calculate atom-thick carbyne chains may be strongest material ever
If outfitted with molecular handles at the ends, it can also be twisted to alter its band gap. With a 90-degree end-to-end rotation, it becomes a magnetic semiconductor.. * Carbyne chains can take on side molecules that may make the chains suitable for energy storage.. * The material is stable at room temperature, largely resisting crosslinks with nearby chains.. Thats a remarkable set of qualities for a simple string of carbon atoms, Yakobson said.. You could look at it as an ultimately thin graphene ribbon, reduced to just one atom, or an ultimately thin nanotube, he said. It could be useful for nanomechanical systems, in spintronic devices, as sensors, as strong and light materials for mechanical applications or for energy storage.. Regardless of the applications, he said, academically, its very exciting to know the strongest possible assembly of atoms.. Based on the calculations, he said carbyne might be the highest energy state for stable carbon. People usually look for what is ...
http://www.innovations-report.com/html/report/materials-science/carbon-s-champion-rice-u-theorists-calculate-atom-221079.html
ARGOM Appendix 2: Guidelines on quality aspects of OTC applicationsARGOM Appendix 2: Guidelines on quality aspects of OTC applications
Prediction of shelf life is facilitated if the data include frequent intermediate stations (in line with the CPMP/ICH recommendations), are derived from several batches, consider a range of conditions, are of high precision, include analysis for breakdown products, and consider the physical properties of the formulation.. The Note for guidance on Evaluation of Stability Data (CPMP/ICH/420/02) provides detailed guidance on evaluation of the data from formal stability studies. The guideline presumes that the required amount of minimum data are available, as outlined under Section 9.4 Minimum data requirements.. For products intended for storage in a freezer no extrapolation beyond the period covered by the long term data is permitted (and testing of a single batch at an appropriate elevated temperature should also be conducted to address the effect of short term excursions outside the proposed label storage condition, such as during shipping or handling).. For other products, the assessment ...
https://www.tga.gov.au/book/export/html/5285
Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide - pdf descargar
Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/aug/150158701128-Effect-of-Cryogrinding-on-Chemical-Stability-of-the-Sparingly-Water-Soluble-Drug-Furosemide.php
Awarded Grants | Grand ChallengesAwarded Grants | Grand Challenges
Louis Roux from LifeAssay Diagnostics (Pty) Ltd. in South Africa, in collaboration with PATH, will develop an easy-to-use, low-cost, strip test for pregnant women in developing countries to detect the onset of proteinuria, which indicates a highly increased risk of preeclampsia/eclampsia. Preeclampsia/eclampsia is a major cause of maternal death, particularly in developing countries. Onset is rapid, and so early diagnosis is crucial, particularly in remote communities where health care is not immediately available. The test measures the ratio of protein to creatinine, which is more accurate than the current protein-only version, and they will produce a low-cost version that can be locally manufactured. They will evaluate the tests performance in comparison to three similar tools on a minimum of 1100 urine samples collected from the CAP trial in South Africa. The study also includes usability and stability evaluations to inform further prototype improvements and product insert development for ...
https://gcgh.grandchallenges.org/grants?Round=all&Phase=all&ProjectID=1031&f%5B0%5D=funding_year%3A2011&f%5B1%5D=funding_year%3A2017&f%5B2%5D=funding_year%3A2016&f%5B3%5D=funding_year%3A2010&f%5B4%5D=field_challenge%253Afield_initiative%3A38519
A facile strategy to achieve high conduction and excellent chemical stability of lithium solid electrolytes | [email protected]
Song, Shufeng, Lu, Jia, Zheng, Feng, Duong, Hai Minh, Lu, Li (2015). A facile strategy to achieve high conduction and excellent chemical stability of lithium solid electrolytes. RSC Advances 5 (9) : 6588-6594. [email protected] Repository. https://doi.org/10.1039/ ...
https://scholarbank.nus.edu.sg/handle/10635/123623
Investigations of rubbery copolyimides for the preparation of asymmetric pervaporation membranes - Archive ouverte HALInvestigations of rubbery copolyimides for the preparation of asymmetric pervaporation membranes - Archive ouverte HAL
It is known that membrane technologies may have a major role to play in the development of environmental-friendly processes, either in gas or liquid separations. In liquid separations, one of the challenging issues is to get membranes with suitable separation properties able also to survive to the exposure of liquid solvents at various temperatures. Aromatic polyimides are known to exhibit a very good stability to a great number of solvents, but their permeability are low because of their rigid carbon skeleton and of their low available free volume; so their uses are mainly limited to gas separations or to filtration processes (MF, UF). To broaden the application area of polyimides in liquid separations, we have prepared and studied the properties of a block ether aromatic copolyimide series where the ether soft block acts both as a selective and a permeable block; we describe attempts to get asymmetric polyetherimide (PEI) membranes having molecular separation properties using various experimental
https://hal.archives-ouvertes.fr/hal-00799574
KetotifenKetotifen
A2 · Amber 2 · No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product ...
https://www.sps.nhs.uk/medicines/ketotifen/
Patente US4073920 - Veterinary composition for the treatment of mammary disorder in animals - Google PatentesPatente US4073920 - Veterinary composition for the treatment of mammary disorder in animals - Google Patentes
A veterinary composition for intramammary administration to animals comprising a suspension of a semi-synthetic penicillin in an oily vehicle, the said oily vehicle comprising tri-glycerides, or propylene glycol di-esters, of fatty acids containing 8-10 carbon atoms, has a short milk out time, good stability and shelf-life.
http://www.google.es/patents/US4073920
professional borosilicate glass total organic carbon vials with label Alibaba
2020/05/26 Package contains:glass cylinders in 4 sizes (10/25/50/100ml), glass beakers in 3 sizes (50/100/250ml), and 2 glass droppers. Product material:cylinder and beaker are both made of high quality 3.3 borosilie glass (GG-17), graduated, laboratory grade glassware.Thick glass, acid and alkali resistant, with good stability.
https://www.bedrijfdongen.nl/08-05/professional--borosilicate-glass-total-organic-carbon-vials-with-label-alibaba.html
Profacgen Updated Stable Cell Line Construction Service for Protein Expression - Get NewsProfacgen Updated Stable Cell Line Construction Service for Protein Expression - Get News
Shirley, NY-Profacgen, a world-leading custom protein service provider for a broad spectrum of industrial and academic clients with a commitment to delivering high-quality data and customer services, is pleased to update its stable cell line construction services. Scientists in the field of protein expression now have access to Profacgens latest stable cell line construction service version supported by cutting-edge facilities.. When large amount of recombinant protein is required, stable expression line construction is recommended for reproducible and cost-effective protein production. Generally, stable cell line construct will take 3 steps: delivery of the target gene into the host cell, screening of stable expression clones, and stability test. For efficient gene delivery and to achieve high integration rate, the company uses lentiviral vector. Limited dilution and antibiotics screening are then applied to select for high-yield, genetically homogenous stable expression monoclones. When ...
http://www.getnews.info/585880/profacgen-updated-stable-cell-line-construction-service-for-protein-expression.html
Sepax Technologies, Inc.Sepax Technologies, Inc.
Sepax Technologies, Inc.Sepax Technologies, Inc.
Current StudentsCurrent Students
The theory and application of control engineering will be discussed. System Modelling: Linear, nonlinear, time invariant, regulator and servomechanisms. Modelling system dynamics by transfer functions, block diagrams, state models. System Response: Transient response of second order systems. Steady state response, steady state errors, frequency response. Stability: simple stability tests, Routh Hurwitz, root locus, Bode and Nyquist. Methods used for design and compensation of control systems such as PID, Ziegler-Nichols tuning rules, lead and lag compensator will be examined. MATLAB software package will be used for control system design and analysis.. ...
http://www.deakin.edu.au/current-students-courses/unit.php?unit=SEE344&return_to=%2Fcurrent-students%2Fcourses%2Fcourse.php%3Fcourse%3DS367%26version%3D3
TÜV SÜD LEISURE - Child safety - Garden play equipment | TÜV SÜD GROUPTÜV SÜD LEISURE - Child safety - Garden play equipment | TÜV SÜD GROUP
The durability of swings or climbing frames also depends on the materials used and their weather resistance. Play equipment with frames of highly durable woods such as oak or redwood is more expensive and less common at DIY markets. Discounters mostly offer standard equipment made of metal or so-called pressure-treated pine, which requires more maintenance.. Before purchasing their selection, parents should feel free to thoroughly inspect the equipment and consider carefully whether the equipment suits their purposes. Solid material and good stability should rate more highly than nice bright colours. Other important factors are:. · The equipment should be free from sharp edges or sharp ...
https://www.tuev-sued.de/sport_leisure/child_safety/garden_play_equipment
DMC composite cone crusherDMC composite cone crusher
High reliability and good stability: the automatic control system of large diameter spindle, heavy duty main frame and independent thin oil lubrication system is adopted to ensure the equipment is durable and reliable. After passing through the crushing chamber, the iron pass protection device can quickly restore the original discharge port and ensure the discharge size.. Convenient maintenance and easy operation: no filler, mechanical locking of vulnerable parts, easy replacement, saving time and labor, greatly saving the investment cost of customers.. Low operating cost and wide application range: due to large production capacity, high reliability and convenient maintenance, the production cost is greatly reduced; the machine adopts the principle of laminated crushing to form a protective layer of material layer, which not only effectively reduces wear and prolongs the service life of vulnerable parts, but also significantly increases the proportion of cube in the product and makes the ...
http://bajlando.pl/PRODUCT/Crusher_machine/DMC_composite_cone_crusher.html
SUNTEST XXL+ FD | AMETEK ATLASSUNTEST XXL+ FD | AMETEK ATLAS
The Atlas SUNTEST XXL+FD is an extra-large light stability test chamber especially tailored towards the needs of consumer goods, food and beverage testing. Its also extremely useful in performing highly accelerated shelf-life tests (ASLT) within days.
http://atlas-mts.com/products/standard-instruments/xenon-weathering/suntest/xxl-fd
Disadvantage Od Cement Ball Mill-ball Mill
Disadvantages of attrition milldisadvantages of attrition millDisadvantage od cement ball mill india disadvantage od cement ball mill disadvantage od cement ball mill is one of the products of our company main products soldit is not only good stability high read more advantage and disadvantages of impact micro pulveriser, disadvantage od cement ball mill
https://www.dentalserviceberlin.de/ball-mill-disadvantage-hgycbibr.html
Tobias | MedifabTobias | Medifab
Our son Tobias is 7 years old and has Angelmans Syndrome and is a very active boy.. We love the Pixi stroller, because it is strong and offers good stability. Tobias can climb in himself with stepping up on the footplate.. The stroller is strong and safe enough so that Tobias cannot tip it over, although he is a very lively boy!. When we go to the mall and have lunch we dont need a special chair for Tobias. The stroller is the right size to sit at the table, and Tobias cannot run away.. The Pixi stroller is excellent in the forest and on the beach, because the stroller has air tires and makes it easy to handle and push. We like also the adjustable ergonomic handlebar which is great when we have a Nanny who is not so tall.. I am happy about the durable seat cover, because Tobias can be messy. The seat cover is easy to remove and wash.. Folding is easy. We have a small car and it goes into the car easily on its side.. Our conclusion is: anytime again with the Pixi stroller!. Tobiass ...
https://www.medifab.co.nz/testimonials/tobias
Self-assembled orthoester cryptands: orthoester scope, post-functionalization, kinetic locking and tunable degradation kinetics...Self-assembled orthoester cryptands: orthoester scope, post-functionalization, kinetic locking and tunable degradation kinetics...
Dynamic adaptability and biodegradability are key features of functional, 21st century host-guest systems. We have recently discovered a class of tripodal supramolecular hosts, in which two orthoesters act as constitutionally dynamic bridgeheads. Having previously demonstrated the adaptive nature of these ho Editors Choice Collection
https://pubs.rsc.org/en/content/articlelanding/2018/sc/c8sc01750f
Stable benchmarking OC? | TechPowerUp ForumsStable benchmarking OC? | TechPowerUp Forums
Im looking for a stable OC for benchmarking. I cant get the Fur stability test to run at anything other than stock. Any tips are welcomed.
https://www.techpowerup.com/forums/threads/stable-benchmarking-oc.68638/
Discount Drugstore: Prendre 200 mg de viagra trusted store!Discount Drugstore: Prendre 200 mg de viagra trusted store!
Term immobilization, trauma, and an internal torque by the rectus femoris at toe off % of their hands or feet, and deciencies of the biceps, or cosmetic deformity, immediately inferior to the overall long. The fasciculus obliquus also plays a critical length has been noted on the operating table, with support beneath the skin fig. The other predominant theory of shoulder arthrodesis box. Provocative stability tests. Templin k the three muscles occurs at approximately right angles, stetson wb. J bone joint surg am. Second, although signicant volume reduction of an unspecified region of the humeral head migrates superiorly. Pelvic radiograph showing a person standing with the frontal plane. P, q, r, s and its contents upwards. Being able to understand the bodys com is again checked. Lens when the general rule of nines fig. J biomech , beumer a, van kampen a fractures of per vertex births, which increased to per with a hemostat fig. Third fractures but has loss of cellularity and staining quality, ...
https://naturalpath.net/natural-news/prendre-200-mg-de-viagra/100/
Constant climate chamber with light dose control - model KBF LQC 240Constant climate chamber with light dose control - model KBF LQC 240
The KBF LQC 240 constant climate chamber with Light Quantum Control for stability tests. Constant climatic conditions thanks to the pre-heating and cooling system.
https://www.binder-world.com/en/Products/Constant-climate-chambers/Series-KBF-LQC/KBF-LQC-240/
10 Queues on East Coast Servers | TORCommunity10 Queues on East Coast Servers | TORCommunity
[news author=EricMusco link=http://www. swtor. com/community/showthread. php?p=9360552#edit9360552 datetime=14. 07. 2017 01:11PM]Alright folks, stability tests look good we will opening
https://torcommunity.com/database/developer-posts/2469-10-queues-on-east-coast-servers
Stability testing (pharmaceutical)Stability testing (pharmaceutical)
Stability testing in pharmaceutical industry is a process that is used to determine the quality of a drug substance or drug ... With stability testing, pharmaceutical industry inspects the quality of drug substances and drug products as per the guidelines ... "STABILITY TESTING OF NEW DRUG SUBSTANCES AND PRODUCTS" (PDF). (Articles with short description, Short description with empty ... Stability testing depends upon the environmental factors like, light source, humidity and ambient temperature as well as the ...
https://en.wikipedia.org/wiki/Stability_testing_(pharmaceutical)
Longitudinal stabilityLongitudinal stability
Some aircraft have low stability to reduce trim drag. This has the benefit of reducing fuel consumption. Some aerobatic and ... The longitudinal stability of an aircraft, also called pitch stability, refers to the aircraft's stability in its plane of ... Low or negative stability is called relaxed stability. An aircraft with low or negative static stability will typically have ... Longitudinal static stability refers to the aircraft's initial tendency on pitching. Dynamic stability refers to whether ...
https://en.wikipedia.org/wiki/Longitudinal_stability
Ship stabilityShip stability
It requires fewer installations, is less vulnerable and it causes less drag. Even better, the required high-quality components ... Add-on stability systems are designed to reduce the effects of waves and wind gusts. They do not increase a vessel's stability ... Depending upon the class of vessel either a stability letter or stability booklet is required to be carried on board. Free ... Damage stability calculations are much more complicated than intact stability. Software utilizing numerical methods are ...
https://en.wikipedia.org/wiki/Ship_stability
Estramustine phosphateEstramustine phosphate
Drug Stability for Pharmaceutical Scientists. Academic Press. pp. 77-. ISBN 978-0-12-411562-0. S. Bernal (21 August 1997). Drug ... 114-. ISBN 978-94-011-4439-1. "Drugs@FDA: FDA Approved Drug Products". United States Food and Drug Administration. Retrieved 29 ... Muller (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 245, 454. ISBN 978-3- ... 287-. ISBN 978-1-4200-0209-6. Samuel J. Murff (20 February 2012). Safety and Health Handbook for Cytotoxic Drugs. Government ...
https://en.wikipedia.org/wiki/Estramustine_phosphate
MorphineMorphine
Loftsson T (2013). Drug Stability for Pharmaceutical Scientists. Elsevier Science & Technology. p. 82. OCLC 1136560730. Heroin ... "Narcotics". DEA Briefs & Background, Drugs and Drug Abuse, Drug Descriptions. U.S. Drug Enforcement Administration. Archived ... In the United Kingdom, morphine is listed as a Class A drug under the Misuse of Drugs Act 1971 and a Schedule 2 Controlled Drug ... drugs.com Drugs.com international listings for Morphine Archived 14 June 2015 at the Wayback Machine Page accessed 2 June 2015 ...
https://en.wikipedia.org/wiki/Morphine
Solubility equilibriumSolubility equilibrium
"Recent advances in co-amorphous drug formulations". Advanced Drug Delivery Reviews. 100: 116-125. doi:10.1016/j.addr.2015.12. ... Rossotti, F. J. C.; Rossotti, H. (1961). "Chapter 9: Solubility". The Determination of Stability Constants. McGraw-Hill. ... Amorphous drugs have higher solubility than their crystalline counterparts due to the absence of long-distance interactions ... The effect of amorphous phase on solubility is widely used to make drugs more soluble. For condensed phases (solids and liquids ...
https://en.wikipedia.org/wiki/Solubility_equilibrium
Mandelic acidMandelic acid
The drugs cyclandelate and homatropine are esters of mandelic acid. Merck Index, 11th Edition, 5599. Bjerrum, J., et al. ... Stability Constants, Chemical Society, London, 1958. See: Winckler, F. L. (1831) "Ueber die Zersetzung des Calomels durch ... It is a useful precursor to various drugs. The molecule is chiral. The racemic mixture is known as paramandelic acid. Mandelic ...
https://en.wikipedia.org/wiki/Mandelic_acid
FuronazideFuronazide
"Stability of drugs in biological media. II. Relations between the stability in culture media and antibacterial activity of some ... The drug has relatively low toxicity. The median lethal dose (LD50, rat oral) was reported as 2,600 mg/kg. Kazuo Miyatake, " ... 18: 631-6. "Drugs - Synonyms and Properties" data were obtained from Ashgate Publishing Co. (US) (Articles without InChI source ... Furonazide is a crystalline tuberculostatic drug substance with a reported melting point of 199-201.5 °C. Furonazide was first ...
https://en.wikipedia.org/wiki/Furonazide
SpaceShipOneSpaceShipOne
... this increases drag while retaining stability. SpaceShipOne completed the first crewed private spaceflight in 2004. That same ... While at apogee the wings are reconfigured into high-drag mode. As the craft falls back it achieves high speeds comparable to ... The wings of SpaceShipOne can be pneumatically tilted forwards into an aerodynamically stable high-drag "feathered" shape. This ... it reconfigures into low-drag glider mode, and glides down to a landing in about 20 minutes. White Knight takes longer to ...
https://en.wikipedia.org/wiki/SpaceShipOne
List of Virgin Galactic launchesList of Virgin Galactic launches
... this increases drag while retaining stability. SpaceShipOne completed the first crewed private spaceflight in 2004. That same ...
https://en.wikipedia.org/wiki/List_of_Virgin_Galactic_launches
HexahydrocannabinolHexahydrocannabinol
Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, All articles with ... Stability of cannabinoids in stored plant material". Journal of Pharmaceutical Sciences. 62 (10): 1601-1605. doi:10.1002/jps. ... Garrett ER, Gouyette AJ, Roseboom H (January 1978). "Stability of tetrahydrocannabinols II". Journal of Pharmaceutical Sciences ... Drug Metabolism and Disposition. 20 (1): 79-83. PMID 1347001. Golombek P, Müller M, Barthlott I, Sproll C, Lachenmeier DW (June ...
https://en.wikipedia.org/wiki/Hexahydrocannabinol
Santa MuerteSanta Muerte
As the drug war in Mexico escalates, Santa Muerte's veneration by drug bosses increases and her image is seen again and again ... It can also signify emotional stability. The color gold signifies economic power, success, money, and prosperity. Green ... drug traffickers will light Santa Muerte's black candle to ensure protection of shipment of drugs across the border. ... Drug lords, like that of La Familia Cartel, take advantage of "gangster foot soldiers'" vulnerability and enforced religious ...
https://en.wikipedia.org/wiki/Santa_Muerte
Activity coefficientActivity coefficient
Klamt, Andreas (2005). COSMO-RS from quantum chemistry to fluid phase thermodynamics and drug design (1st ed.). Amsterdam: ... "Project: Ionic Strength Corrections for Stability Constants". IUPAC. Archived from the original on 29 October 2008. Retrieved ...
https://en.wikipedia.org/wiki/Activity_coefficient
War on drugsWar on drugs
Stability: International Journal of Security and Development. 2 (1): Art. 9. doi:10.5334/sta.aw. Lindsay, Reed (March 25, 2003 ... news site focusing on drug war in Latin America Drug Policy Facts Drug War Distortions Major Studies of Drugs and Drug Policy ... African-American drug users made up for 35% of drug arrests, 55% of convictions, and 74% of people sent to prison for drug ... 37-43 How Goes the "War on Drugs": An Assessment of U.S. Drug Problems and Policy. RAND Corporation Drug Policy Research Center ...
https://en.wikipedia.org/wiki/War_on_drugs
Nanoparticles for drug delivery to the brainNanoparticles for drug delivery to the brain
Solid lipid nanoparticles are designed to overcome these shortcomings and have an excellent drug release and physical stability ... Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood-brain barrier (BBB) ... Kreuter, Jörg (2013). "Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?". Advanced Drug ... better results for drug delivery relative to lipid-based nanoparticles because they may increase the stability of the drugs or ...
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Physical pharmacyPhysical pharmacy
Physical stability and appeal of the drug. Labeling of storage conditions and expiration dates. Smith, Blaine Templar (2015-10- ... and distribution of drug products and serves as the foundation for the stable and proper use of medical drugs. It covers areas ... It emphasis on the physical characteristics and actions of the drug delivery system before the same is given to the patient. It ... Physical pharmacy deals with the science that works on the following aspects which are related to the development of a drug ...
https://en.wikipedia.org/wiki/Physical_pharmacy
Crime in BoliviaCrime in Bolivia
United Nations Office on Drugs and Crime, 2013. Ledebur, K.; Youngers, C. (2013). "From Conflict to Collaboration: An ... Innovative Approach to Reducing Coca Cultivation in Bolivia". Stability: International Journal of Security and Development. 2 ( ...
https://en.wikipedia.org/wiki/Crime_in_Bolivia
FlunitrazepamFlunitrazepam
Gautam L, Sharratt SD, Cole MD (February 19, 2014). "Drug facilitated sexual assault: detection and stability of ... "Benzodiazepines drug profile". European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). January 8, 2015. Zevzikovas A ... the drug has not been approved by the Food and Drug Administration and is considered to be an illegal drug; as of 2016 it is ... making drug-assisted robbery a more commonly reported problem than drug-assisted rape. Flunitrazepam is a Schedule III drug ...
https://en.wikipedia.org/wiki/Flunitrazepam
Confidence-building measures in Central AmericaConfidence-building measures in Central America
The proposal also included suggestions of new tasks for the armed forces, such as involvement in the control of drugs and ... democratic stability; human rights; economic security; protection of the environment; critical poverty; non-proliferation and ... and cooperation in the struggle against drugs. The specific references to "confidence-building mechanisms" and "transparency in ...
https://en.wikipedia.org/wiki/Confidence-building_measures_in_Central_America
NafcillinNafcillin
Several drugs with a narrow therapeutic window, such as warfarin and nifedipine, are metabolized by CYP2C9. Nafcillin contains ... salts added as stability media. These added salts could cause edema or fluid accumulation. It would be prudent to avoid this ... Articles with short description, Short description matches Wikidata, Drugs with non-standard legal status, ECHA InfoCard ID ... "Adverse Events Lead to Drug Discontinuation More Commonly among Patients Who Receive Nafcillin than among Those Who Receive ...
https://en.wikipedia.org/wiki/Nafcillin
Relaxed stabilityRelaxed stability
A less stable aircraft requires smaller control deflections to initiate maneuvering; consequently drag and control surface ... In aviation, relaxed stability refers to an aircraft with low or negative stability. An aircraft with negative stability will ... Relaxed stability designs are not limited to military jets. The McDonnell Douglas MD-11 has a neutral stability design which ... To ensure stability for safe flight, an LSAS (Longitudinal Stability Augmentation System) was introduced to compensate for the ...
https://en.wikipedia.org/wiki/Relaxed_stability
Receptor activated solely by a synthetic ligandReceptor activated solely by a synthetic ligand
... but with differing stabilities in solution) have also been commercially developed (see for aqueous stability). RASSLs and ... DREADDs are used as a tool to evaluate both the neuronal pathways and behaviors associated with drug-cues and drug addiction. ... "Stability of Water-Soluble DREADD Ligands in Solution - A Technical Review". HelloBio.com. Retrieved 2018-12-05. "Clozapine N- ... Another known agonist is perlapine, a hypnotic drug approved for treating insomnia in Japan. It acts as an activator of Gq-, Gi ...
https://en.wikipedia.org/wiki/Receptor_activated_solely_by_a_synthetic_ligand
2β-Propanoyl-3β-(4-tolyl)-tropane2β-Propanoyl-3β-(4-tolyl)-tropane
Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, Tropanes, Stimulants ... It also shows marked increase in metabolic stability. In contrast to the findings of cocaine effects, WF-11 has been shown to ... Drug and Alcohol Dependence. 61 (1): 15-21. doi:10.1016/S0376-8716(00)00119-8. PMID 11064180. v t e (Articles with short ... Norepinephrine-dopamine reuptake inhibitors, Ketones, All stub articles, Nervous system drug stubs). ...
https://en.wikipedia.org/wiki/2β-Propanoyl-3β-(4-tolyl)-tropane
Coiled coilCoiled coil
Yu YB (Oct 2002). "Coiled-coils: stability, specificity, and drug delivery potential". Advanced Drug Delivery Reviews. 54 (8): ... Burkhard P, Ivaninskii S, Lustig A (May 2002). "Improving coiled-coil stability by optimizing ionic interactions". Journal of ... Mason JM, Arndt KM (Feb 2004). "Coiled coil domains: stability, specificity, and biological implications". ChemBioChem. 5 (2): ... Mason JM, Arndt KM (Feb 2004). "Coiled coil domains: stability, specificity, and biological implications". ChemBioChem. 5 (2): ...
https://en.wikipedia.org/wiki/Coiled_coil
Nanoparticle drug deliveryNanoparticle drug delivery
Deng, Jiexin; Huang, Leaf; Liu, Feng (May 2010). "Understanding the structure and stability of paclitaxel nanocrystals". ... "Application of Drug Nanocrystal Technologies on Oral Drug Delivery of Poorly Soluble Drugs". Pharmaceutical Research. 30 (2): ... Drug-dendrimer conjugation can elongate the half-life of drugs. Currently, dendrimer use in biological systems is limited due ... Advanced Drug Delivery Reviews, 2011. 63(3): p. 136-151. Miyazaki, S., C. Yokouchi, and M. Takada, External control of drug ...
https://en.wikipedia.org/wiki/Nanoparticle_drug_delivery
Progesterone carboxymethyloximeProgesterone carboxymethyloxime
Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, Abandoned drugs, ... Basu, Krishnakali; Kildsig, Dane O.; Mitra, Ashim K. (1988). "Synthesis and kinetic stability studies of progesterone ... Genito-urinary system drug stubs, Nervous system drug stubs). ... Drugs with low aqueous solubility are not absorbed well in the ... Ron Liu (18 January 2008). Water-Insoluble Drug Formulation, Second Edition. CRC Press. pp. 105-. ISBN 978-1-4200-0955-2. v t e ...
https://en.wikipedia.org/wiki/Progesterone_carboxymethyloxime
EDTMPEDTMP
The anti-cancer drug Samarium (153Sm) lexidronam is also derived from EDTMP. Svara, J.; Weferling, N.; Hofmann, T. "Phosphorus ... It has good chemical stability and thermal tolerance. It shows excellent scale inhibition ability under temperature 200 °C. It ...
https://en.wikipedia.org/wiki/EDTMP
Renée VivienRenée Vivien
After the death and breakup, Vivien became depressed and turned to drugs and alcohol. In 1902 Vivien became romantically ... Zuylen provided much-needed emotional support and stability. Zuylen's social position did not allow for a public relationship, ... She turned increasingly to alcohol, drugs, and even attempted suicide by taking laudanum, an opium derivative; the attempt ... drug abuse, and anorexia nervosa. She was interred at Passy Cemetery in the same exclusive Parisian neighbourhood where she had ...
https://en.wikipedia.org/wiki/Renée_Vivien
M80 StilettoM80 Stiletto
A disadvantage is that the five hulls give a large "wetted area", increasing drag. The M80 Stiletto is a U.S. Navy vessel ... The multihull uses its width to gain stability. Its five slim hulls create virtually no bow wave, thus obviating the "hull ... In 2008, the Stiletto deployed on a 70-day mission for USSOUTHCOM as part of a joint agency operation that included the Drug ... The hull design allows stability at high speeds and rough conditions without the need for foils or lifting devices. Its shallow ...
https://en.wikipedia.org/wiki/M80_Stiletto
Suvendra Nath BhattacharyyaSuvendra Nath Bhattacharyya
The treatment, combined with other drugs have been reported to be effective in treating the disease commonly known as Kala azar ... On his current project, miRNA expoprt and Stability, he has worked on the mammalian immune and cancer cells and reportedly ... "miRNA expoprt and Stability". 2016. Retrieved 4 November 2016. "Suvendra N. Bhattacharyya on ResearchGate". Author profile. ... "Battling Kala azar: Indian scientists overcoming drug resistance". India Medical Times. 3 September 2013. Retrieved 4 November ...
https://en.wikipedia.org/wiki/Suvendra_Nath_Bhattacharyya
Uridine monophosphate synthaseUridine monophosphate synthase
Yablonski MJ, Pasek DA, Han BD, Jones ME, Traut TW (May 1996). "Intrinsic activity and stability of bifunctional human UMP ... monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design". Structure. 16 (1): 82-92. ... The driving force for these fusion events seems to be the acquired thermal stability. Homo sapiens OPRTase and ODCase ... In Leishmania donovani, separate OPRTase does not have detectable activity possibly due to lower thermal stability or lack of ...
https://en.wikipedia.org/wiki/Uridine_monophosphate_synthase
Classical AnatoliaClassical Anatolia
Order and stability was restored when Diocletian (284-305) obtained power following the death of the last Crisis Emperors, ... central government in rome was often far from civil and military commanders in the field, and local ambitions often dragged ... The third partition of 301 BC was no more effective at bringing stability to the region than its predecessors. Demetrius, who ... He was succeeded by Orontes III (317-260 BC) and relative stability apart from his unsuccessful struggles with the minor ...
https://en.wikipedia.org/wiki/Classical_Anatolia
Uncertainty quantificationUncertainty quantification
An example of a source of this uncertainty would be the drag in an experiment designed to measure the acceleration of gravity ... Cardenas, IC (2019). "On the use of Bayesian networks as a meta-modeling approach to analyse uncertainties in slope stability ... Cardenas, IC (2019). "On the use of Bayesian networks as a meta-modeling approach to analyse uncertainties in slope stability ...
https://en.wikipedia.org/wiki/Uncertainty_quantification
Thurston TealThurston Teal
The drag produced having the landing gear stowed in the up position is higher than in the extended position, and this reduces ... The Teal design features a high wing with tip floats for lateral stability. The horizontally opposed engine is mounted tractor ...
https://en.wikipedia.org/wiki/Thurston_Teal
NorovirusNorovirus
Ali ES, Rajapaksha H, Jillian MC, Petrovsky N (2016). "Norovirus drug candidates that inhibit viral capsid attachment to human ... or maintaining capsid stability. The protein MDA-5 may be the primary immune sensor that detects the presence of noroviruses in ... by reverse transcription polymerase chain reaction are being employed by governmental laboratories such as the Food and Drug ...
https://en.wikipedia.org/wiki/Norovirus
Africans in GuangzhouAfricans in Guangzhou
Many marriages have stability issues due to the difficulties in keeping visas. The majority of the Chinese who live and marry ... There has been a recent growth of drug trafficking among groups of foreigners from around the world, including Africa. A ... The Guangzhou Public Security Bureau carried out a major drug bust with 1,300 police officers raiding the Lihua Hotel (Dragon ... "535 Nigerians languish in Chinese prisons for drug trafficking". The Point. May 1, 2017. Archived from the original on August 9 ...
https://en.wikipedia.org/wiki/Africans_in_Guangzhou
Proto-oncogene tyrosine-protein kinase SrcProto-oncogene tyrosine-protein kinase Src
HSP90 inhibitor NVP-BEP800 has been described to affect stability of Src tyrosine kinase and growth of T-cell and B-cell acute ... Other tyrosine kinase inhibitor drugs that are in clinical trials include bosutinib, bafetinib, AZD-0530, XLl-999, KX01 and ... "HSP90 inhibitor NVP-BEP800 affects stability of SRC kinases and growth of T-cell and B-cell acute lymphoblastic leukemias". ...
https://en.wikipedia.org/wiki/Proto-oncogene_tyrosine-protein_kinase_Src
Job interviewJob interview
In some cases, a review of Facebook may reveal undesirable behaviors such as drunkenness or drug use. Despite the relevance of ... emotional stability, extroversion, openness to new experiences Interest, goals, and values: Applicant motives, goals, and ... What prescription drugs are you currently taking? Applicants with disabilities may be concerned with the effect that their ... current users of illegal drugs are not covered under this Act). A person is covered if he has a disability that substantially ...
https://en.wikipedia.org/wiki/Job_interview
Belt frictionBelt friction
2. Dragging coefficient of friction μ g {\displaystyle \mu _{g}} and angle α {\displaystyle \alpha } are satisfying the ... Construction of the drive-pulley system - This involves strength and stability of the material used, like the pulley, and how ...
https://en.wikipedia.org/wiki/Belt_friction
Psychology of religionPsychology of religion
William James was also interested in mystical experiences from a drug-induced perspective, leading him to make some experiments ... Thus, performance of rituals may foster social group stability. There is considerable literature on the relationship between ... Shamans all over the world and in different cultures have traditionally used drugs, especially psychedelics, for their ... In these communities the absorption of drugs leads to dreams (visions) through sensory distortion. The psychedelic experience ...
https://en.wikipedia.org/wiki/Psychology_of_religion
September 1968September 1968
American drag racer and 2001 NHRA Rookie of the Year; in Houston (killed in accident, 2004) Leah Pinsent, Canadian television ... Terrorism and Democratic Stability (Routledge, 2017) p92 Bertil Lintner, Burma in Revolt: Opium and Insurgency since 1948 ( ...
https://en.wikipedia.org/wiki/September_1968
IndinavirIndinavir
After 38 weeks, 6% of the people in the three-drug group died while 11% of the people died in the two-drug group. There were ... Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT (December 2005). "Kinetic, stability, and structural ... Viral resistance to the drug leads to the drug becoming useless since the virus evolves to have cells that are able to resist ... The Food and Drug Administration (FDA) approved indinavir on March, 1996, making it the eighth antiretroviral drug approved. It ...
https://en.wikipedia.org/wiki/Indinavir
Direct metal masteringDirect metal mastering
... of the cutter head as it was dragged through the copper disc. The DMM copper master disc can be plated to produce the required ... as well as the more linear phase response of DMM improve the overall stability and depth-of-field in the stereo image. In ...
https://en.wikipedia.org/wiki/Direct_metal_mastering
ChildbirthChildbirth
Active management is the administration of a uterotonic drug within one minute of fetal delivery, controlled traction of the ... improved cardio-respiratory stability and blood glucose levels, and improved breastfeeding duration. A 2016 Cochrane review ... Anaesthetists or anesthesiologists are medical doctors who specialise in pain relief and the use of drugs to facilitate surgery ... Inductions are most often performed either with prostaglandin drug treatment alone, or with a combination of prostaglandin and ...
https://en.wikipedia.org/wiki/Childbirth
Universal basic income around the worldUniversal basic income around the world
They noted that they have not observed increased use of alcohol or illicit drugs; significant changes in labor relations, birth ... 15 pose a considerable threat to political stability and democratic values, as indicated by the recent election outcomes in the ...
https://en.wikipedia.org/wiki/Universal_basic_income_around_the_world
TylosinTylosin
In general, tylosin is licensed for the treatment of infections caused by organisms susceptible to the drug, but it has also ... Loke ML, Ingerslev F, Halling-Sørensen B, Tjørnelund J (April 2000). "Stability of Tylosin A in manure containing test systems ... Tylosin, drugs.com "Tylosin-Tylan". petplace.com. "Tylosin , the Antimicrobial Index Knowledgebase - TOKU-E". Palmer FJ, ... Drugs with no legal status, Drugboxes which contain changes to verified fields, Drugboxes which contain changes to watched ...
https://en.wikipedia.org/wiki/Tylosin
Graham RichardsonGraham Richardson
... not to the point of being psychiatrically impaired but it did me a lot of harm in terms of stability and the capacity to ... alleged to be a product of gambling and drugs, into NSW Labor. Richardson told the commission on 28 March 1980 that Casey had ...
https://en.wikipedia.org/wiki/Graham_Richardson
Joint Task Force NorthJoint Task Force North
The JTF was originally activated as Joint Task Force Six (JTF-6) in November 1989 with a purely counter-drug mission. In 2004 ... member to the DoD's Task Force for Business and Stability Operations (TFBSO); Special Forces LTC Eric Buckland, U.S. Army, Ret ...
https://en.wikipedia.org/wiki/Joint_Task_Force_North
Diseases of povertyDiseases of poverty
It is managed by life prolonging drugs known as Antiretroviral drugs (ARVs). TB was discovered by Robert Koch in 1882. It is ... and political stability of entire societies". Women and children are often put at a high risk of being infected by ... Of 1393 new drugs brought into use over a period of 25 years (1975-1999), only a total of thirteen, less than 1%, related to ... Of 20 MNC drug companies surveyed for research on PRDs, only two had projects targeted towards these neglected PRDs. However, ...
https://en.wikipedia.org/wiki/Diseases_of_poverty
Le PaysLe Pays
Tual reminds her that after he had dragged himself ashore from the shipwreck, he nearly died in the Hrafuaga, a dangerous ... The fourth theme represents stability, associated with the heroine's father. Kaethe, an Icelandic girl - soprano Tual, a Breton ...
https://en.wikipedia.org/wiki/Le_Pays
Power: A New Social AnalysisPower: A New Social Analysis
A period of naked power may end by foreign conquest, the creation of stability, and/or the rise of a new religion (Russell 1938 ... as when the leader among sheep is dragged along by chains to get the rest of the flock to follow. Finally, the power of ...
https://en.wikipedia.org/wiki/Power:_A_New_Social_Analysis
Political views of Christopher HitchensPolitical views of Christopher Hitchens
Hitchens has called for the abolition of the "War on Drugs," which he described as an "authoritarian war" during a debate with ... Why should the left care about the stability of undemocratic regimes? Wasn't it a good thing to destabilise the regime of ...
https://en.wikipedia.org/wiki/Political_views_of_Christopher_Hitchens
Stonewall riotsStonewall riots
And then I started doing drag. ... I started becoming a drag queen "Feature Doc 'Pay It No Mind: The Life & Times of Marsha P. ... "It is generally believed that those who engage in overt acts of perversion lack the emotional stability of normal persons", and ... "You go to bars because of what drag queens did for you and these bitches tell us to quit being ourselves!" Both the drag queens ... Rich - Poor - Drag - Butch. Gays stood together and fought in a mass act of resistance. Those days were the birth pangs of the ...
https://en.wikipedia.org/wiki/Stonewall_riots
SlipwaySlipway
In both cases heavy chains are attached to the ship and the drag effect is used to slow the vessel once afloat until tugboats ... stability and weight the engines might have not been fitted or the superstructure may not be completed. In a perpendicular ...
https://en.wikipedia.org/wiki/Slipway
2019 Turkish offensive into north-eastern Syria2019 Turkish offensive into north-eastern Syria
... presence in the area is not going to benefit us when it comes to stability, security, and [stopping] the genocide and ethnic ... pro-Turkey factions kidnap a pharmacist in Tal Abyad as he refused to sell prohibited analgesic drugs for them • The Syrian ... and replace them with Russian forces to maintain stability. Meanwhile, Turkey began to appoint mayors in several northern ... and replace them with Russian forces to maintain stability. Meanwhile, Turkey began to appoint mayors in several northern ...
https://en.wikipedia.org/wiki/2019_Turkish_offensive_into_north-eastern_Syria
RacemizationRacemization
The configurational stability of a drug is therefore an area of interest in pharmaceutical research. The production and ... The drug is therefore not considered safe for use by women of child-bearing age, and while it has other uses, its use is ... Another commonly used drug is ibuprofen which is only anti-inflammatory as one enantiomer while the other is biologically inert ... Many psychotropic drugs show differing activity or efficacy between isomers, e.g. amphetamine is often dispensed as racemic ...
https://en.wikipedia.org/wiki/Racemization
Pre-Bötzinger complexPre-Bötzinger complex
Another synthetic drug specific to the adenosine A2A receptor subtype is CGS-21680 that has been shown to cause apneas in 14- ... Two key features of the pre-BötC are its stability and its ability to adapt to changing environmental and behavioral conditions ...
https://en.wikipedia.org/wiki/Pre-Bötzinger_complex
History of SingaporeHistory of Singapore
Prostitution, gambling, and drug abuse (particularly of opium) were widespread. Chinese criminal secret societies (analogous to ... The British were concerned about communist influence and labour strikes which were undermining Singapore's economic stability, ...
https://en.wikipedia.org/wiki/History_of_Singapore
Re-education through laborRe-education through labor
Most detainees in re-education through labor facilities are reported to be drug users, petty criminals, and prostitutes, as ... China's security agencies have defended the use of the system as being necessary to maintain social stability. A 1997 report in ... Although drug abusers are ostensibly placed in re-education through labor to be treated for their addictions, some testimonial ... and trafficking illegal drugs, as well as political dissidents, petitioners, and Falun Gong followers. It was separate from the ...
https://en.wikipedia.org/wiki/Re-education_through_labor
Todd ManningTodd Manning
After Todd is sent to prison for Marty's rape, he vows he will escape, and does so by drugging himself and forcing himself to ... demonstrating Todd's damaged personality and calling into question his mental stability. Carlivati said that Todd was convinced ... He witnesses Dani collapse from a drug overdose due to her abuse of oxycodone. While she is recovering at the hospital, an ... to plant drugs in Jason Webb's jacket. All I knew was that my first name was Todd. I don't know what happened next. They called ...
https://en.wikipedia.org/wiki/Todd_Manning
Browsing by Subject Drug StabilityBrowsing by Subject "Drug Stability"
Stability of essential drugs in tropical climates : Zimbabwe / H. Nazerali, T. Muchemwa, H. V. Hogerzeil  ... Accelerated stability studies of the drugs in pharmaceutical forms under simulated tropical conditions  ... Groot, A. N. J. A. de; Vree, T. B; Hogerzeil, Hans V; Walker, G. J. A; WHO Action Programme on Essential Drugs (‎World Health ... Stability of vaccines / Artur Galazka  Galazka, Artur M; WHO Expanded Programme on Immunization (‎World Health ...
https://extranet.who.int/iris/restricted/browse?authority=Drug+Stability&type=mesh
Article Metrics] Multi-access drug delivery network and stability | IJNArticle Metrics] Multi-access drug delivery network and stability | IJN
... drug volumes) can be trapped and moved dynamically within the molecular bus networks, in which the required drug delivery ... In practice, the large molecular networks such as ring, star, and bus networks can be integrated to form a large drug delivery ... In this work, crosstalk effects of about 0.1% are noted, which can be neglected and does not affect the network stability. ... A novel design of a multi-drug delivery network and diagnosis using a molecular network is proposed. By using a pair of ...
https://www.dovepress.com/article_metric.php?article_id=8136
Erowid.org: Erowid Reference 7727 : Stability study of the designer drugs MDA, MDMA and MDEA in water, serum, whole blood,...Erowid.org: Erowid Reference 7727 : Stability study of the designer drugs 'MDA, MDMA and MDEA' in water, serum, whole blood,...
De Leenheer AP Stability study of the designer drugs MDA, MDMA and MDEA in water, serum, whole blood, and urine under various ... "Stability study of the designer drugs MDA, MDMA and MDEA in water, serum, whole blood, and urine under various storage ... A controlled study was undertaken to determine the stability of the designer drugs MDA, MDMA and MDEA in pooled serum, whole ... "Stability study of the designer drugs MDA, MDMA and MDEA in water, serum, whole blood, and urine under various storage ...
https://erowid.org/references/refs_view.php?ID=7727&S=De_Leenheer_AP&SField=Author
The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded...The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded...
... impact the stability of compounded levothyroxine suspensions. Using the three available brands of levothyroxine tablets, ... To evaluate the effect on drug stability, pH modifiers were added to a suspension. As demonstrated by high-performance liquid ... The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded ... and drug concentrations on stability, and thus the beyond-use date of the compounded levothyroxine liquid formulations. The pH ...
https://ijpc.com/Abstracts/Abstract_basic.cfm?ABS=4458
Application of Precipitation Methods for the Production of Water-insoluble Drug Nanocrystals: Production Techniques and...Application of Precipitation Methods for the Production of Water-insoluble Drug Nanocrystals: Production Techniques and...
... method to produce water-insoluble drug nanocrystals, and the stability issues of nanocrystals. The ... Keywords: Water insoluble drug, nanocrystals, anti-solvent, precipitation, stability, crystal grow and nucleation, stabilizer, ... Keywords: Water insoluble drug, nanocrystals, anti-solvent, precipitation, stability, crystal grow and nucleation, stabilizer, ... This review focuses on using precipitation (bottom-up) method to produce water-insoluble drug nanocrystals, and the stability ...
http://www.eurekaselect.com/article/52274
New research on drug stability could help create more effective medicines - Clinical Trials ArenaNew research on drug stability could help create more effective medicines - Clinical Trials Arena
New research on drug stability could help create more effective medicines. Researchers from the Universities of Cambridge and ... Number of ongoing Clinical Trials (for drugs) involving Stable Angina by Phase. Number of ongoing Clinical Trials (for drugs) ... "If they develop a drug based on the glass form of a molecule and it crystallises, they will not only have lost a potentially ... Copenhagen have developed a new method of predicting the physical stability of potential drug candidates, which could help in ...
https://www.clinicaltrialsarena.com/news/new-research-drug-stability-help-create-effective-medicines/
Development of a protocol to investigate the stability of drugs used by Qatars National Ambulance Service in rapid response...Development of a protocol to investigate the stability of drugs used by Qatar's National Ambulance Service in rapid response...
Development of a protocol to investigate the stability of drugs used by Qatars National Ambulance Service in rapid response ... Development of a protocol to investigate the stability of drugs used by Qatars National Ambulance Service in rapid response ... Prehospital, Thermal stability, Medications, Ambulance Service, Emergency Medical Service. Subjects:. B100 Anatomy, Physiology ... Conclusion: Based on the findings of this study, the results may have a significant impact on how some of the drugs are handled ...
http://nrl.northumbria.ac.uk/id/eprint/48287/
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer | Nature CommunicationsHistone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer | Nature Communications
Proteomic characterization of post-translational modifications in drug discovery *Lin-hui Zhai ... 5: EPZ-regulated E3 ligases target AR and MYC stability.. a Comparison of genes that are differentially expressed by EPZ (n = ... 3: DOT1L inhibition leads to loss in AR protein levels by decreasing its protein stability.. ... l Graphical summary of DOT1L dependent regulation of MYC expression and its association with AR and MYC protein stability. ...
https://www.nature.com/articles/s41467-020-18013-7?error=cookies_not_supported&code=e8282e59-df71-416f-88a5-ccbc15c0da6e
Extractables and Leachables | Mechanical Stability TestingExtractables and Leachables | Mechanical Stability Testing
From drug compatibility and Extractables and Leachables studies to Mechanical Stability Testing, we offer insight into ... From drug compatibility and extractables and leachables studies to system performance and mechanical stability testing, we ... Drug-container interaction. SIMS depth profiling, SEM cross-section analysis, and ICP-OES/MS solution analysis are used to ... SCHOTT pharma services offers a range of screening packages using specialized analytics to assess the risks of drug-container ...
https://www.schott.com/en-si/services/pharma-analytics
Results of search for 'su:{Drug stability.}' › WHO HQ Library catalog
Text; Format: print Publication details: Boston, Mass. : Harvard School of Public Health, 1999Availability: Items available for loan: WHO HQ (1)Call number: WB 330 99AS. ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BDrug%20stability.%7D
Stability and Support Operations | RANDStability and Support Operations | RAND
A collection of RAND research on the topic of Stability and Support Operations ... Geoengineering, the Russia-Ukraine Crisis, Biosimilar Drugs: RAND Weekly Recap. This weekly recap focuses on technologies that ... Stability and Support Operations. Featured. As part of peacekeeping efforts, stability operations-post-conflict military ... Select RAND Research on Counterinsurgency, Stability Operations, Support to Foreign Internal Defense, Nation-Building, and ...
https://www.rand.org/topics/stability-and-support-operations.html
Bacitracin (EENT) Monograph for Professionals - Drugs.comBacitracin (EENT) Monograph for Professionals - Drugs.com
Stability. Storage. Ophthalmic. Ointment. Bacitracin: 20-25°C.. Bacitracin and polymyxin B with or without neomycin: 15-25°C. ... Subscribe to Drugs.com newsletters Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, ... Drugs.com Mobile Apps The easiest way to lookup drug information, identify pills, check interactions and set up your own ... Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and ...
https://www.drugs.com/monograph/bacitracin-eent.html
Stability and enhancement of berry juice colorStability and enhancement of berry juice color
This study was designed to investigate the color stability and copigmentation of … ... Stability and enhancement of berry juice color J Agric Food Chem. 2004 May 19;52(10):3106-14. doi: 10.1021/jf035507i. ... This study was designed to investigate the color stability and copigmentation of four different berry juices enhanced by ...
https://pubmed.ncbi.nlm.nih.gov/15137861/
Extended Stability for Parenteral Drugs | ASHPExtended Stability for Parenteral Drugs | ASHP
Extended Stability for Parenteral Drugs published on Jun 2017 by American Society of Health-System Pharmacists. ... Stability data for many parenteral drugs beyond 24 hours are often difficult to find in the published literature. This has been ... ASHPs sixth edition of Extended Stability for Parenteral Drugs, by Caryn Dellamorte Bing, RPh, MS, FASHP and Anna Nowobilski- ... The highly competitive nature of the home infusion industry also led to the development of unpublished drug stability data, ...
https://publications.ashp.org/abstract/book/9781585285280/9781585285280.xml?rskey=jQhzjk&result=5
Mitigating Drug Stability Challenges Through Cocrystallization. | AAPS PharmSciTech;24(2): 62, 2023 Feb 09. | MEDLINEMitigating Drug Stability Challenges Through Cocrystallization. | AAPS PharmSciTech;24(2): 62, 2023 Feb 09. | MEDLINE
Mitigating Drug Stability Challenges Through Cocrystallization. Mitigating Drug Stability Challenges Through Cocrystallization ... Drug stability plays a significant role in the pharmaceutical industry from early-phase drug discovery to product registration ... Finally, the stability concern of fixed-dose or drug combinations and the challenges associated with cocrystals are also ... Representative case studies wherein the drug stability issue is addressed through pharmaceutical cocrystals have been discussed ...
https://pesquisa.bvsalud.org/portal/resource/pt/mdl-36759434
Drug Cuts Tardive Dyskinesia in Psychiatric PatientsDrug Cuts Tardive Dyskinesia in Psychiatric Patients
Psychiatric Stability In a related poster presentation, Dr Josiassen pointed out that valbenazine is the grandchild of the drug ... High Drug Costs Exclude Most Neurology Patients From Cutting-Edge Treatment * Tardive Dyskinesia Drug Safe, Effective for ... would this drug have the same side-effect profile as the parent drug?" he added. ... investigators have now submitted the drug for US Food and Drug Administration (FDA) approval. ...
http://www.medscape.com/viewarticle/870113
Sensorimotor Development Mobility & Stability Flashcards | QuizletSensorimotor Development Mobility & Stability Flashcards | Quizlet
Study with Quizlet and memorize flashcards containing terms like PRONE 0-2 months, PRONE 5-6 months, PRONE 5-8 months and more.
https://quizlet.com/721409790/sensorimotor-development-mobility-stability-flash-cards/
Drug Product (Finished, Stability) Sampling Procedure - Pharma Beginners
The stability sample shall be collected as per the stability test request form given to QC. ... As per stability test request form. Uncoated Tablets. 20 tablets. Av.Wt.≤200mg. 200 tablets. 20 g. 50 tablets as per protocol. ... SOP for Drug Product Sampling. 1.0 PURPOSE:. * *To define the procedure for the sampling of trial, in-process, finish, micro, ... 8.0 ANNEXURES FOR DRUG PRODUCT SAMPLING:. Annexure-1: Sampling Log Register. Sample Intimation No. ...
https://pharmabeginers.com/sampling-sop/
221 242 - Drug Stability Testing (Ezlopitant) - Antec Scientific221 242 - Drug Stability Testing (Ezlopitant) - Antec Scientific
For more than 30 years Antec Scientific has been the world leading supplier of analytical instrumentation based on electrochemistry (EC ...
https://antecscientific.com/wpfd_file/221_242-drug-stability-testing-ezlopitant-2/
Promoting Health Equity | Drug Overdose | Injury CenterPromoting Health Equity | Drug Overdose | Injury Center
Promoting Health Equity in the Response to Drug Overdose ... Disadvantaged by reduced economic stability. *Experiencing ... Health Equity in the Response to Drug Overdoseexternal icon. The Health Equity in the Response to Drug Overdose webpage ... Groups of people who may be disproportionately affected by the drug overdose crisis include, but are not limited to those:. * ... Drug Overdose Deaths involving Cocaine and Psychostimulants with Abuse Potential among Racial and Ethnic Groups - United States ...
https://www.cdc.gov/drugoverdose/health-equity/info.html
Saudi Arabia and Egypt discuss regional stability, Palestinian cause, Renaissance Dam | Al Arabiya EnglishSaudi Arabia and Egypt discuss regional stability, Palestinian cause, Renaissance Dam | Al Arabiya English
Python in Australia bites, drags boy into pool World News * 3 3 UN says Myanmar sentences seven students to death World News ... Stability in Libya. The two sides also stressed the need to preserve Libyas stability, unity, and territorial integrity, ... ejecting any attempt to affect freedom of navigation as this constitutes a threat to regional security and stability. ... the rejection of regional interference in Arab internal affairs and attempts to destabilize the regions security and stability ...
https://english.alarabiya.net/News/middle-east/2020/12/01/Saudi-Arabia-Egypt-stress-maritime-freedom-in-the-Gulf-Red-Sea
The Effectiveness of Core Stability Exercises - Full Text View - ClinicalTrials.govThe Effectiveness of Core Stability Exercises - Full Text View - ClinicalTrials.gov
Studies a U.S. FDA-regulated Drug Product:. No. Studies a U.S. FDA-regulated Device Product:. No. ... Experimental: Core stability exercises This group will be divided in two: core stability exercises (CSE) plus conventional ... while the other half will receive core stability exercises and core stability exercises plus transcutaneous electrical nerve ... The Effectiveness of Core Stability Exercises (CORE). The safety and scientific validity of this study is the responsibility of ...
https://clinicaltrials.gov/ct2/show/NCT03975985
Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base...
We have used ultraviolet melting techniques to study the effect on stability of incorporating the nucleoside analogue 2-deoxy- ... Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base ... Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base ... We have used ultraviolet melting techniques to study the effect on stability of incorporating the nucleoside analogue 2-deoxy- ...
https://www.oncology.ox.ac.uk/publications/400423?8c8b8c0c-71f3-11ed-856e-061b866677b4
Comprehensive Drug Stability Test Chamber XCH-430SD Manufacturer | Thchamber.comComprehensive Drug Stability Test Chamber XCH-430SD Manufacturer | Thchamber.com
... provide High-performance stability test chambers. Best Price. 15+ Years for temperature technology. Get A Quote Free. ... professional Comprehensive Drug Stability Test Chamber XCH-430SD manufacturer, ... Home /Stability test Chamber /. Comprehensive Stability Test Chamber 430L-830L. /Comprehensive Drug Stability Test Chamber XCH- ... Comprehensive Drug Stability Test Chamber XCH-430SD. The multi-chamber Stability Chamber, Temp Only or Temp/RH. Adopts quality ...
https://www.thchamber.com/Comprehensive-Drug-Stability-Test-Chamber-XCH-430SD_p34.html
Home - Drug Stability Studies (Ph.D) - LibGuides at Riphah International UniversityHome - Drug Stability Studies (Ph.D) - LibGuides at Riphah International University
Welcome to the Online Public Access Catalog (OPAC). This catalog provides you bibliographic information of print books available in all campus libraries of the University and provides you the facility of 2 types of searches; basic search and advance search to find the exact book or list of books you required.. ...
https://libguides.riphah.edu.pk/c.php?g=455767&p=3114599
Marijuana Lawyers Help Cannabis Testing Labs Seeking Stability | Marijuana Drug FactsMarijuana Lawyers Help Cannabis Testing Labs Seeking Stability | Marijuana Drug Facts
http://www.marijuanadrugfacts.com/marijuana-laws/marijuana-lawyers-help-cannabis-testing-labs-seeking-stability ...
http://www.marijuanadrugfacts.com/marijuana-laws/marijuana-lawyers-help-cannabis-testing-labs-seeking-stability
Essay on ➥ The Stability of a Drug: Physical and Chemical ConditionsEssay on ➥ The Stability of a Drug: Physical and Chemical Conditions
The essay discusses the various factors that can affect the stability of a drug, including physical and chemical conditions, ... The Impact of Physical and Chemical Conditions on Drug Stability. 1. Introduction. The stability of a drug is affected by both ... What data is necessary for an evaluation of drug stability?. In order to evaluate drug stability, data on the chemical ... The implications of findings from an evaluation of drug stability depend on the particular drugs involved and the results of ...
https://essayholic.com/the-impact-of-physical-and-chemical-conditions-on-drug-stability/
Medicine Stability Chamber,Drug Stability Test Chamber,Laboratory Stability Testing ChamberMedicine Stability Chamber,Drug Stability Test Chamber,Laboratory Stability Testing Chamber
Labonce medicine stability test chamber,includes three functions of temperature,humidity and light. Alarm system,dual chamber ... Tags : Stability chamber Test Chamber with factory price Drug testing chamber stability guidelines ich Programmable Temperature ... Stability chamber equipped with temperature humidity visible light and NUV light. *Stability chamber with the newly air way ... Stability chamber equipped with temperature humidity visible light and NUV light. *Stability chamber with the newly air way ...
https://www.labonce.com/medicine-stability-chamber-gs-gmp_c73
Mandol (Cefamandole): Uses, Dosage, Side Effects, Interactions, WarningMandol (Cefamandole): Uses, Dosage, Side Effects, Interactions, Warning
... drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. ... STABILITY Reconstituted Mandol (cefamandole) is stable for 24 hours at room temperature (25°C) and for 96 hours if stored under ... Drugs & Vitamins. Drugs A-Z Generic Drugs A-Z Drugs by Classification Drugs Comparison (Drug Vs. Drug) Vitamins & Supplements ... home drugs a-z list side effects drug center mandol (cefamandole) drug ...
https://www.rxlist.com/mandol-drug.htm
Stability indicating thin-layer chromatographic method for estimation of antidiabetic drug Remogliflozin etabonate | Future...Stability indicating thin-layer chromatographic method for estimation of antidiabetic drug Remogliflozin etabonate | Future...
The method was applied for the analysis of drug in tablet formulation, and it can be used for routine quality control analysis ... The degradant peaks were well resolved from the drug peak with acceptable resolution in their Rf value. An accurate and precise ... Forced degradation studies were performed, and drug was found to be highly susceptible to acid, base hydrolysis, and oxidative ... and robustness and applied for the estimation of drug in tablet dosage form. The Rf value of Remogliflozin etabonate was ...
https://fjps.springeropen.com/articles/10.1186/s43094-021-00230-6/tables/2
2022Pharmaceutical2019TherapeuticsEXCIPIENTSAffect the stabilitySubstancesTest ChamberSearchInteractionToxicitySerumDegradationBioavailabilityMicrobiologicalEmotional StabilitySystemicCompoundsVitroEfficacyPharmaceuticalsStudiesVariabilitySuspensionsPurpose of stabilityStudyMoleculesStableBiologicsDestabilizeCore stabilityImprove stabilityRegional stabilityInvestigateProductOverdosePhysicalTemperatureThermalAssessHomelessnessMedicinesTherapeuticQualitySamplesPharmacodynamicVivoDoseAnalyticalSubstanceAddictionWidelyFactorsAcceptableDeterminationOverdosesPatientsDataSimulationAvoidDiscoveryPharmacyDosageSodiumChemicalEvaluate
20223
  • Medically reviewed by Drugs.com on May 4, 2022. (drugs.com)
  • Free Essay Samples (November 29, 2022) The Impact of Physical and Chemical Conditions on Drug Stability . (essayholic.com)
  • Oguntoye LL(2022)The Absorption from Topical Formulations and Its Functional Stability by Antioxidant Activity. (scitechnol.com)
Pharmaceutical15
  • With its expanded coverage, many updates, and new information, Extended Stability provides even more support, making it a "must have" for any practice in which pharmaceutical solutions are prepared and administered. (ashp.org)
  • IMSEAR at SEARO: Validated stability indicating gradient RP-HPLC method for the estimation of antihypertensive drugs in bulk and pharmaceutical dosage forms. (who.int)
  • A generic drug product must meet the standards, established by 'United States Food and Drug Administration' in USA, 'Central drugs standards control organization' in India, and 'National Medical Product Administration' in China to be approved to successfully enter the pharmaceutical market. (researchgate.net)
  • At a recent drug shortage summit convened by the FDA and Duke University, Martin VanTrieste, a pharmaceutical executive and president and CEO of Civica Rx, acknowledged that "all drug shortages are the result of economics, financial and management decisions. (statnews.com)
  • Drug Channels delivers timely analysis and provocative opinions from Adam J. Fein, Ph.D., the country's foremost expert on pharmaceutical economics and the drug distribution system. (drugchannels.net)
  • A simple, selective, precise and stability indicating RP-HPLC method for analysis of Deferasirox in bulk drug and pharmaceutical dosage forms was developed and validated. (ujconline.net)
  • Given that drug stability is an essential quality attribute for a drug product and the quality-by-design approach (QbD) is a best solution to build quality in all pharmaceutical products we focussed on the critical material attributes (CMAs), specifically relating to the physical stability of any given drug. (smu.ac.za)
  • This review highlights physical drug stability in relation to CMAs and how this ultimately link to the finished pharmaceutical product. (smu.ac.za)
  • Aucamp, M & Milne, M 2019, ' The physical stability of drugs linked to quality-by-design (QbD) and in-process technology (PAT) perspectives ', European Journal of Pharmaceutical Sciences , vol. 139, 105057. (smu.ac.za)
  • The following status describes submitted unfinished drugs, including the marketing categories of Active Pharmaceutical Ingredient (API), Drug for Further Processing, Bulk for Human Drug Compounding, and Bulk for Animal Drug Compounding. (hipaaspace.com)
  • Furthermore, I learned about regulations in the pharmaceutical industry, good manufacturing practice (GMP), and tests that are required to bring a drug to market. (ncl.ac.uk)
  • The Regional Committee is invited to advise on the adoption of the attached draft guidelines on Stability Testing of Active Substances and Pharmaceutical Products in countries of the Eastern Mediterranean Region. (who.int)
  • These guidelines are intended to define the stability data package for active substances and pharmaceutical products that is sufficient for a registration application within countries of the World Health Organization's Eastern Mediterranean Region [1]. (who.int)
  • The purpose of stability testing is to provide evidence on how the quality of an active substance or pharmaceutical product varies with time under the influence of a variety of environmental factors such as temperature, humidity and light. (who.int)
  • Relevant of mutagenicity and clastogenici- angiosarcomas of the liver, which carcinogens discussed in this chap- ty, including the induction of sister are rare tumours, were identified in ter do not include pharmaceutical chromatid exchange (SCE), chro- humans, rats, and mice exposed to drugs classified in Group 1, which mosomal aberrations (CA), and mi- vinyl chloride. (who.int)
20194
  • abstract = "{\textcopyright} 2019 The physical stability of solid-state forms in which drugs may exist is in some sense an overlooked aspect. (smu.ac.za)
  • There was a 51% increase of hepatitis A infections, from 24,900 estimated infections in 2018 to 37,700 estimated infections in 2019, primarily due to person-to-person outbreaks occurring among people who use drugs and people experiencing homelessness . (cdc.gov)
  • Injection drug use remains the primary risk behavior identified among persons with acute hepatitis C. The number of reported acute hepatitis B cases remained stable from 2018 to 2019, as it has over the last decade. (cdc.gov)
  • Data show hopeful signs of progress in HIV prevention in recent years, with new HIV infections falling 8% from 2015 to 2019, after a period of general stability in new infections in the United States. (cdc.gov)
Therapeutics1
  • A wide variety of compounds are unstable (are degraded) when incubated in blood or plasma at rates that are inconsistent with the PK properties necessary for drug therapeutics. (medicilon.com)
EXCIPIENTS5
  • This is the first study demonstrating the impact of tablet brand, with different excipients, and drug concentrations on stability, and thus the beyond-use date of the compounded levothyroxine liquid formulations. (ijpc.com)
  • The complexation efficiency between drug-excipients, microparticles and films was studied using Fourier-transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). (opinvisindi.is)
  • Excipients not only affect the stability of proteins and other biologics, they also determine the appropriate operating parameters for the lyophilization process. (biopharminternational.com)
  • Because the conditions during freezing and drying are different, the stresses on biologic drug substances are different, and combinations of excipients are often required to provide the protection and stabilization required for a given protein, monoclonal antibody, etc. (biopharminternational.com)
  • These excipients are most critical to the structure and ultimately the function of freeze-dried biologic drug products. (biopharminternational.com)
Affect the stability3
  • Storage temperature did not affect the stability of the suspensions during the 4-week study. (ijpc.com)
  • To test the hypothesis that bone quality may affect the stability of anchorage devices implanted in a rat model. (bvsalud.org)
  • Bone quality may affect the stability of mini-implants. (bvsalud.org)
Substances3
  • Extractables studies determine the amount of organic and inorganic substances extracted from primary packaging materials that could potentially migrate into the drug product. (schott.com)
  • and secondary drying via desorption-exposes biologic drug substances to harsh conditions and stresses that can affect their structure and function. (biopharminternational.com)
  • Intended to guide the selection of drugs in countries where the need is great and the resources are small, the list identifies a core group of prophylactic and therapeutic substances judged capable of meeting the vast majority of health needs and thus deserving priority in purchasing decisions and procurement schemes. (who.int)
Test Chamber1
  • Guangdong Yuanyao Test Equipment Co., Ltd. focuses on the R&D and production of drug stability test chamber, and provides the most suitable solution according to the actual needs of customers. (yuanyao-tech.com)
Search1
  • Results of search for 'su:{Drug stability. (who.int)
Interaction3
  • The chemical durability of primary packaging is vital in preventing drug-container interaction. (schott.com)
  • SCHOTT pharma services offers a range of screening packages using specialized analytics to assess the risks of drug-container interaction and establish strategies to avoid them. (schott.com)
  • SIMS depth profiling, SEM cross-section analysis, and ICP-OES/MS solution analysis are used to determine the mechanism of drug-container interaction. (schott.com)
Toxicity8
  • A potential complication of treatment with thiopurine drugs is damage to the bone marrow (hematopoietic toxicity). (medlineplus.gov)
  • In people who are found to have reduced enzyme activity, the drugs may be given at a significantly lower dose or different medications can be used to reduce the risk of hematopoietic toxicity. (medlineplus.gov)
  • Another 11 percent have moderately reduced levels of TPMT activity that increase their risk of hematopoietic toxicity with thiopurine drug treatment. (medlineplus.gov)
  • People with two low-activity copies of the TPMT gene in each cell have TPMT deficiency and are at the greatest risk of developing hematopoietic toxicity when treated with thiopurine drugs unless they are given much less than the usual dose. (medlineplus.gov)
  • People with two high-activity copies have normal TPMT activity and do not have an increased risk of hematopoietic toxicity with thiopurine drug treatment. (medlineplus.gov)
  • 1975. Drug-biomolecule interations: Drug toxicity and vitamin coenzyme depletion. (cdc.gov)
  • Natural agonists, such as cyclic dinucleotides, activate the cGAS-STING pathway, but concerns over poor cytosolic entry, serum stability and systemic toxicity have been major limitations for clinical translation. (mdanderson.org)
  • Somerset, N.J. - June 24, 2014 - Redwood Bioscience and Catalent Pharma Solutions, the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products, today announced the results of an in vivo toxicology study, demonstrating that an Antibody Drug Conjugate (ADC) generated using the proprietary SMARTag™ platform has a better toxicity profile than a conventional ADC. (catalent.com)
Serum2
  • A controlled study was undertaken to determine the stability of the designer drugs MDA, MDMA and MDEA in pooled serum, whole blood, water and urine samples over a period of 21 weeks. (erowid.org)
  • The concentrations of the individual designer drugs in the various matrices were monitored over time, in the dark at various temperatures (-20, 4 or 20 degrees C), for a low (+/- 6 ng/ml for water, serum and whole blood and +/- 150 ng/ml for urine) and a high concentration level (+/- 550 ng/ml for water, serum and whole blood and +/- 2500 ng/ml for urine). (erowid.org)
Degradation4
  • In order to evaluate drug stability, data on the chemical structure of the drug, how it degrades over time, and conditions that can accelerate degradation are necessary. (essayholic.com)
  • The purpose is to understand the factors affecting stability, possible degradation pathways and degradation products, and to provide basis for preparation process screening, packaging materials and container selection, and storage conditions determination. (yuanyao-tech.com)
  • Moisture naturally entering the canisters catalyzes a reaction that converts oxygen into iron oxide, thus decreasing the oxygen-related degradation of the drug pro-duct. (pharmtech.com)
  • As the method could effectively separate the drug from its degradation product, it can be employed as a stability indicating one. (ujconline.net)
Bioavailability3
  • By optimizing the lead compound, modifying the structure of the compound to improve the plasma stability of the compound, prolong the action time of the drug in the body, increase the exposure in the body, reduce the clearance rate of the compound, and increase the bioavailability, thereby improving its pharmacokinetics and Pharmacodynamic properties are necessary for drug development. (medicilon.com)
  • It improves the bioavailability of drug (Kim et al. (springer.com)
  • In an era where strategies such as amorphous solid dispersions or co-amorphous preparations might provide answers to stumbling blocks such as poor drug solubility and bioavailability, the physical stability of such solid-state preparations should be a priority. (smu.ac.za)
Microbiological2
  • The drug stability refers to the ability of raw materials and preparations to maintain their physical, chemical, biological and microbiological properties. (yuanyao-tech.com)
  • An additional goal of the formulator for all molecules is to keep the formulation as simple as possible while achieving acceptable chemical, physical, and microbiological stability, according to Gregory A. Sacha, senior research scientist, BioPharma Solutions, Baxter Healthcare. (biopharminternational.com)
Emotional Stability2
  • Achieving mental and emotional stability is a top priority for people struggling with addiction, and many addicts require months or even years before they are ready for new relationships. (recoveryfirst.org)
  • She credits exercise with increasing both her stamina and her emotional stability. (medlineplus.gov)
Systemic1
  • The influence of drugs and systemic factors on orthodontic tooth movement. (bvsalud.org)
Compounds5
  • Plasma (blood) stability determination is a widely used, simple test that can eliminate compounds in drug discovery screens. (medicilon.com)
  • If a researcher investigates the stability of short peptide proteasome inhibitors with potential anti-tumor activity in mouse plasma and whole blood, it provides a reference for further research on the druggability of compounds 1 and 2 to be studied. (medicilon.com)
  • The study found that the stability of compounds 1 and 2 in mouse plasma was higher than their stability in whole blood, and compound 1 was more stable than compound 2 in mouse plasma and whole blood. (medicilon.com)
  • Once inside the body, these drugs are converted to toxic compounds that kill immune system cells in the bone marrow. (medlineplus.gov)
  • The TPMT enzyme "turns off" thiopurine drugs by breaking them down into inactive, nontoxic compounds. (medlineplus.gov)
Vitro2
  • Development of a new drug is a long and costly process and to avoid attritions due to inadequate metabolic and pharmacokinetic data it is important to determine these early by the use of in vitro systems. (chalmers.se)
  • The potential haemolytic effect of three chemotherapeutic drugs and aspirin was tested in vitro by gluthathione stability tests. (who.int)
Efficacy7
  • WASHINGTON, DC - The efficacy of valbenazine, a drug being tested for use in the treatment of tardive dyskinesia, does not depend on the underlying psychiatric illness being treated, nor does the drug destabilize psychiatric status, new phase 2 trial data show. (medscape.com)
  • Main objective: To compare the efficacy of conventional physiotherapy versus an approach based on a Core Stability Exercises (CSEs) program, in terms of dynamic balance, gait and functional rehabilitation at the end of the intervention (5 weeks) and in the long term (sustained effect over time at 3 and 6 months), in sub-acute post-stroke patients. (clinicaltrials.gov)
  • The goal of this study is to understand differences in regulatory requirements, bio-equivalence data, drug registration, approval process and, guidelines associated with the generic drug filing in the USA, India, and China and also provide enough information for the drug safety and efficacy in humans. (researchgate.net)
  • As a drug delivery system they enhance the therapeutic efficacy of the drug and minimize adverse effect and toxic reactions. (springer.com)
  • Coadministration with antibiotics decreases efficacy by altering colonic bacterial flora needed to convert sodium picosulfate to active drug. (medscape.com)
  • To qualify for inclusions in the list, a drug must be supported by sound and adequate data demonstrating safety, efficacy, and consistent performance in a variety of medical settings. (who.int)
  • A final section presents guiding principles intended to help small national drug regulatory authorities develop a system of legislative and administrative procedures that can assure quality, efficacy and safety, even when resources are limited. (who.int)
Pharmaceuticals1
  • The NDC Code 68382-500-16 is assigned to "Omeprazole " (also known as: "Omeprazole"), a human prescription drug labeled by "Zydus Pharmaceuticals (USA) Inc.". The product's dosage form is capsule, delayed release, and is administered via oral form. (hipaaspace.com)
Studies7
  • From drug compatibility and extractables and leachables studies to system performance and mechanical stability testing, we offer insight and support for all packaging challenges. (schott.com)
  • Several studies and a systematic review have shown that implementing core stability exercises may be a viable strategy for improving trunk performance and dynamic sitting balance, standing balance, and gait in post-stroke patients. (clinicaltrials.gov)
  • Hydrolysis, oxidation, reduction, and carboxylic acid are some of the most common reactions that occur during drug stability studies. (essayholic.com)
  • In two studies of childhood cancer specialists, one in 2015 and another in 2017 , two-thirds of pediatric oncologists reported that their patients' clinical care was compromised by drug shortages - exactly what Alice and her family were potentially facing. (statnews.com)
  • In this vital role, you will provide support to the Product Quality (PQ) organization as a subject matter expert of clinical and commercial product stability studies, and GMP data management. (biospace.com)
  • The Specialist Stability builds and monitors stability studies within quality systems (e.g. (biospace.com)
  • O Consultation on Regional Guidelines on Stability Studies of Medicines and Biologicals, held in Jeddah in February 2006. (who.int)
Variability1
  • A similar understanding of how species contribute to multiple forms of stability, e.g. variability, resilience, resistance, and persistence is lacking, yet similar mechanisms may prevail (Donohue et al. (qub.ac.uk)
Suspensions3
  • This study aims to determine whether tablet brand (i.e., formulation), concentration, storage conditions, as well as pH, impact the stability of compounded levothyroxine suspensions. (ijpc.com)
  • Using the three available brands of levothyroxine tablets, suspensions were compounded at concentrations of 15 µg/mL and 25 µg/mL and stored at 4°C and 22°C. Samples were withdrawn weekly for 4 weeks, and chemical stability was evaluated using high-performance liquid chromatographic analysis. (ijpc.com)
  • Drag racing suspensions and drag racing tires have gone hand-in-hand with the evolution of drag racing. (cartechbooks.com)
Purpose of stability1
  • The purpose of stability research is to investigate the law of change of the nature of the drug substance or preparation over time under the influence of temperature, humidity and other conditions, to provide a scientific basis for the production, packaging, storage, transportation conditions and determination of expiration date of the drug to ensure the safety and effectiveness of clinical drug use. (yuanyao-tech.com)
Study12
  • Our study demonstrated no significant loss of the designer drugs in water and urine at any of the investigated temperatures for 21 weeks. (erowid.org)
  • This study demonstrates that the designer drugs, MDA, MDMA and MDEA are stable when stored at -20 degrees C for 21 weeks, even in haemolysed whole blood. (erowid.org)
  • Conclusion: Based on the findings of this study, the results may have a significant impact on how some of the drugs are handled in the pre-hospital setting, especially, possible modification of the recommended expiration date specified by manufacturers to ensure patient safety. (northumbria.ac.uk)
  • This study was designed to investigate the color stability and copigmentation of four different berry juices enhanced by phenolic acids and commercial color enhancers. (nih.gov)
  • This study assess the effectiveness of core stability exercises performed in subacute phase of stroke. (clinicaltrials.gov)
  • Expected results: The study will provide useful information on the short and long term effects of a physiotherapy rehabilitation program based on core stability exercises, as well as the potential use of a mobile app to reinforce long term adherence to unsupervised home-based physiotherapy. (clinicaltrials.gov)
  • We have used ultraviolet melting techniques to study the effect on stability of incorporating the nucleoside analogue 2'-deoxy-3-deazaadenosine (d3cA) into the duplex 5'-d(CGCAATCG)-3'-d(GCGTTAGC). (ox.ac.uk)
  • It aims to simulation study the stability of the drug under short-term abnormal conditions that may be encountered during transportation and storage, and preliminarily predict the long-term stability of the sample under the specified storage conditions. (yuanyao-tech.com)
  • Products were subjected to a 3-month stability study. (who.int)
  • in the world and the preferred drug among children and In that sense, it is interesting to highlight the study adolescents, even when considering socioeconomic and Violence, Drugs and AIDS in Schools, which Unesco cultural differences among countries(1). (bvsalud.org)
  • Improper alcohol use in an early stage turns into a study, it is reported that alcohol is the most consumed predisposing factors for health, social and economic drugs in schools, involving about 2.5 million students. (bvsalud.org)
  • [ 56 ] In one study, withholding antithyroid drugs for just over 2 weeks before radioiodine treatment resulted in the lowest failure rate. (medscape.com)
Molecules4
  • However, the newly developed method will allow previously discarded drug molecules to be re-considered for use in a stable glass form. (clinicaltrialsarena.com)
  • Nanoemulsions are a colloidal particulate system in the submicron size range acting as carriers of drug molecules. (springer.com)
  • Removing water from a formulation (drying) to create a freeze-dried solid also presents a challenge to the stability of some large molecules. (biopharminternational.com)
  • During my PhD, my research work was focused on improving the drug delivery of hydrophobic drugs using carrier molecules such as polymeric micelles and surface active ionic liquid mixed micelles. (ncl.ac.uk)
Stable4
  • The drug was more stable at the higher concentration of 25 µg/mL than at 15 µg/mL. (ijpc.com)
  • XCH-830SD Multi-chamber Temp/RH Stability Chamber adopts quality imported components and manufacturing process, with stable and reliable performance, independent control and climatic test of three boxes and temperature and humidity control of A, B and C boxes. (thchamber.com)
  • Such measurements require stable encapsulation, that is no escape of the substrate into bulk solution during experiments, and a way to perturb protein stability without affecting the chaperonin system itself. (elifesciences.org)
  • Lyophilization, or freeze drying, is a well-recognized method for obtaining stable biologic drug products that have short shelf-lives in solution form. (biopharminternational.com)
Biologics1
  • Catalent Pharma Solutions is the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products. (catalent.com)
Destabilize2
  • The Saudi-Egyptian Consultation Committee stressed the rejection of regional interference in Arab internal affairs and attempts to destabilize the region's security and stability, reported a joint press release on Tuesday. (alarabiya.net)
  • The two sides also stressed the need to preserve Libya's stability, unity, and territorial integrity, rejecting foreign interference in its affairs and attempts to destabilize the internal and regional conditions by supporting terrorism and extremism. (alarabiya.net)
Core stability3
  • Half of participants will receive conventional physiotherapy, while the other half will receive core stability exercises and core stability exercises plus transcutaneous electrical nerve stimulation (TENS). (clinicaltrials.gov)
  • This group will be divided in two: core stability exercises (CSE) plus conventional therapy (CP) and CSE with transcutaneous electrical nerve stimulation (TENS) plus CP. (clinicaltrials.gov)
  • The guidelines seek to exemplify the core stability data package required for registration. (who.int)
Improve stability2
  • The implications of findings from an evaluation of drug stability depend on the particular drugs involved and the results of the analysis, but could include changes to manufacturing or storage procedures to improve stability, as well as expiration dates for products with shorter shelf lives. (essayholic.com)
  • 2012). Some phenols are used as sunscreen agents for skin protection, and as UV filters in cosmetic products and plastics to improve stability (e.g., benzophenone-3). (cdc.gov)
Regional stability1
  • We hope the relevant cooperation can be conducive to maintaining regional peace and promoting regional stability and prosperity," he said. (asianage.com)
Investigate4
  • Methods: A safe and practical solution had to be found and should be approved by the Production committee to investigate the thermal stability of a range of 13 medications over different periods of time (Table 1). (northumbria.ac.uk)
  • The purpose is to investigate the stability of the drugs during transportation, storage, and use. (yuanyao-tech.com)
  • The purpose is to investigate the stability of the drug by accelerating the chemical or physical change rate of the drug in the commercial packaging. (yuanyao-tech.com)
  • It is thus becoming imperative to investigate the various types of phase transformations a specific solid-state form of a drug may undergo. (smu.ac.za)
Product11
  • The QA person shall do a sampling of the drug product as per the below-mentioned procedure and shall keep the sample in a duly labelled sample container. (pharmabeginers.com)
  • The test product is placed in a sealed clean container, placed in the stability chamber at 60°C for 10 days, and samples are taken on the 5th and 10th days to test the relevant indicators. (yuanyao-tech.com)
  • If the test product changes significantly, perform the test in the same method at 40°C in the stability chamber. (yuanyao-tech.com)
  • Reducing oxygen content and regulating humidity safeguard product integrity and stability. (pharmtech.com)
  • Generic drugs are identical, indistinguishable within an acceptable bio-equivalent level for the innovator product name counterpart esteems to the 'Pharmacokinetics and Pharmacodynamics' properties. (researchgate.net)
  • In USA and India, in Module II there is complete information on the quality overall summary, but in China, there is complete information about a Drug substance, whereas in module III in USA and India there is complete information about Drug Substance and Drug Product, but in China, module III contains complete information about drug product only. (researchgate.net)
  • An emulgent, in addition to its emulsifying properties, should be nontoxic and its taste, odour and chemical stability should be compatible with the product. (springer.com)
  • LIMS), owns and handles product quality/stability data, may serve as a primary author on regulatory filings, and also directly participates in & supports site-based GMP inspections. (biospace.com)
  • The labeler code, product code, and package code segments of the National Drug Code number, separated by hyphens. (hipaaspace.com)
  • Indicates the type of product, such as Human Prescription Drug or Human OTC Drug. (hipaaspace.com)
  • General information about the drug product, including the proprietary and established name of the drug, the type of dosage form and route of administration to which the label applies, qualitative and quantitative ingredient information, the pharmacologic or therapeutic class of the drug, and the chemical name and structural formula of the drug. (hipaaspace.com)
Overdose3
  • The Health Equity in the Response to Drug Overdose webpage features actionable resources with reports, frameworks, guidance, and resource repositories from local, state, and national entities. (cdc.gov)
  • CDC and the National Association of County and City Health Officials (NACCHO) partnered to compile the literature available on health equity in the national drug overdose response. (cdc.gov)
  • She previously led CDC prescription drug overdose team and served as advisor to New York City's Health Commissioner. (cdc.gov)
Physical4
  • Researchers from the Universities of Cambridge and Copenhagen have developed a new method of predicting the physical stability of potential drug candidates, which could help in the development of more effective medications. (clinicaltrialsarena.com)
  • The stability of a drug is affected by both physical and chemical conditions. (essayholic.com)
  • It has improved physical stability. (springer.com)
  • Also, to critically assess the applicability of process analytical tools that may be sensitive enough to monitor not only chemical but also physical drug stability. (smu.ac.za)
Temperature2
  • While one data logger was fixed to the metal net divider at the back of the rapid response vehicle, each bag contained a radio-frequency identification (RFID) tag for tracing, two data loggers to measure the temperature and humidity every 10 minutes over a 3 to 12-month period, and an initial total of 15 drug samples (Table 1). (northumbria.ac.uk)
  • The addition of microparticles to the films was found to reduce the mucoadhesive capacity, peak detachment force, tensile strength and elasticity, but improved the stability at room temperature. (opinvisindi.is)
Thermal1
  • Besides, the thermal stability and organic solvent resistance were improved. (bvsalud.org)
Assess3
  • This short report uses 2010 to 2012 National Survey on Drug Use and Health (NSDUH) to assess any mental illness/serious mental illness and treatment among those ages 18 to 25 and major depressive episodes and treatment among those aged 16 to 17. (samhsa.gov)
  • The project will assess how species traits, e.g. body mass or linkage density, explain variation in their contribution to multiple forms of stability. (qub.ac.uk)
  • The project will combine experimental field and lab work with computer simulations to resolve and assess the stability of model marine food webs. (qub.ac.uk)
Homelessness1
  • [14] , [15] People experiencing homelessness or housing instability are also more likely to engage in activities associated with increased chances of HIV acquisition or transmission, including substance use, injection drug use, and having multiple sex partners-factors that can also contribute to higher rates of sexually transmitted infections (STIs) and hepatitis. (cdc.gov)
Medicines1
  • This success rate isn't due to new or cutting-edge medicines, but to decades-old and off-patent drugs for which there are no alternatives. (statnews.com)
Therapeutic1
  • Organized according to therapeutic group, the list includes information on route of administration, dosage forms, and strengths for each of 286 essential drugs. (who.int)
Quality3
  • It's important to consider important details like the ability to choose your own doctor, quality customer service and premium stability from year to year. (wellmark.com)
  • Development and validation of analytical methods such as Standard Operating Procedures (SOPs) to determine drug quality analysis. (ncl.ac.uk)
  • Where someone lives-both in terms of the stability, affordability, and quality of housing, and the characteristics of their neighborhood-can have a profound impact on their health and wellbeing. (cdc.gov)
Samples2
  • Results: Six medication bags have been specially prepared with the drug samples presented in Table 1. (northumbria.ac.uk)
  • SOP for Sampling procedure for withdrawal of Stability samples. (pharmabeginers.com)
Pharmacodynamic1
  • Lead compound optimization to improve the plasma stability of the compound helps to improve the pharmacokinetic and pharmacodynamic properties of the compound in vivo. (medicilon.com)
Vivo1
  • If only the liver metabolism stability of the compound is concerned and the plasma stability is ignored during the development of new drugs, the problem of in vivo stability of the compound may not be effectively solved. (medicilon.com)
Dose2
  • We cannot continue to overlook the economic drivers that lead to shortages of older drugs costing just dollars per dose that offer cures for cancer while newer chemotherapy agents costing hundreds of thousands of dollars that may prolong life by just a few months are rarely, if ever, in short supply. (statnews.com)
  • People with one high-activity copy and one low-activity copy have moderately reduced enzyme activity and are also at increased risk of this complication unless given a significantly lower dose of the drug. (medlineplus.gov)
Analytical1
  • A compound's plasma stability is often determined by an appropriate analytical method, such as LC-UV or LC-MS. (medicilon.com)
Substance2
  • Generally, the test substance of the bulk drug is placed in a suitable container (such as a weighing bottle or a petri dish) and spread into a thin layer ≤5mm thick, and the loose bulk drug is spread into a thin layer ≤10mm thick for testing. (yuanyao-tech.com)
  • Although you might assume that public attention to a drug would reflect underlying trends in use of that substance, that is often not the case. (reason.com)
Addiction1
  • Suffering from drug addiction and manic depression, Cobain had become destructive and suicidal, though his management and label were able to hide the extent of his problems from the public until April 8, 1994, when he was found dead of a self-inflicted shotgun wound. (sat-universe.com)
Widely1
  • Survey data released this month by the federal government cast doubt on a couple of widely accepted beliefs about drug use trends: 1) that the nation is in the midst of an escalating "heroin epidemic" and 2) that loosening marijuana prohibition encourages teenagers to smoke pot. (reason.com)
Factors1
  • Plasma stability is one of the important factors in the evaluation of drug readiness. (medicilon.com)
Acceptable2
  • For years drug warriors have been warning that easing up on marijuana, or even talking about it, would "send the wrong message" to the youth of America, encouraging them to smoke pot by making it seem safe and socially acceptable. (reason.com)
  • it is rapidly degraded in acid media, but has acceptable stability under alkaline conditions. (hipaaspace.com)
Determination2
  • In drug development, the determination of the stability of a compound in rat plasma and the plasma protein binding rate can provide a basis for clinical drug development and research of the compound and establish a corresponding detection method. (medicilon.com)
  • 13. Gedrange T, Hietschold V, Mai R, Wolf P, Nicklisch M, Harzer W. An evaluation of resonance frequency analysis for the determination of the primary stability of orthodontic palatal implants. (bvsalud.org)
Overdoses2
  • CDC and NACCHO identified tools and resources that can help health departments consider root causes of health inequities across populations and the interconnected system of upstream inequities when addressing drug overdoses in their jurisdictions. (cdc.gov)
  • Such clubs will save lives lost to overdoses through heroin tainted by fentanyl, "disrupt" profits for drug dealers from organized crime gangs, eliminate an avenue for money laundering and thereby make housing more affordable. (druglawreform.info)
Patients7
  • The emergency physician (EP) should strive to identify patients who might benefit from appropriate referrals for drug and alcohol problems. (medscape.com)
  • Even more worrisome, nearly 70 percent of the oncologists reported that their hospital or practice lacked any type of formal guidance for how to make decisions about which patients should get chemotherapy drugs that are in short supply. (statnews.com)
  • Many healthcare providers recommend that patients' TPMT activity levels be tested before thiopurine drugs are prescribed. (medlineplus.gov)
  • In recent years, with the increasing number of patients with depression , the efficient synthesis of the first-line antidepressant drug duloxetine intermediate (S-N,N-dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine, S-DHTP) has attracted great attention . (bvsalud.org)
  • For the first time, the list includes a selection of essential drugs needed for the palliative care of cancer patients. (who.int)
  • In general, higher dosages are required for patients who have large goiters, have low radioiodine uptake, or who have been pretreated with antithyroid drugs. (medscape.com)
  • Patients currently taking antithyroid drugs must discontinue the medication at least 2 days prior to taking the radiopharmaceutical. (medscape.com)
Data1
  • What data is necessary for an evaluation of drug stability? (essayholic.com)
Simulation2
  • Named in honor of Belmont Trustee Emeritus and Chairman of Clayton Associates, the late Clayton McWhorter, and his brother, the late pharmacist Fred McWhorter, McWhorter Hall offers a number of chemistry and research labs, a working retail pharmacy, Drug Information Center, simulation teaching labs and so much more. (belmont.edu)
  • The first and second floors of McWhorter Hall are home to state-of-the-art medical simulation spaces, a drug information center, Belmont's Health Services clinic and a licensed, state-of-the-art pharmacy, both of which serve students, faculty and staff. (belmont.edu)
Avoid2
  • People who complete drug rehab usually find that they must make a number of social sacrifices to avoid cravings and stay sober. (recoveryfirst.org)
  • Avoid or Use Alternate Drug. (medscape.com)
Discovery1
  • Cutaneous leishmaniasis drug discovery scheme. (ajtmh.org)
Pharmacy1
  • The Christy Houston Foundation Drug Information Center supports the College of Pharmacy and College of Health Sciences and Nursing faculty and staff in their educational efforts and trains students in medication information management. (belmont.edu)
Dosage1
  • The first part of the report provides updated information on several components of national drug policy necessary to assure that essential drugs, corresponding to essential health needs, are available at all times in adequate amounts and in the proper dosage.The seventh WHO model list of essential drugs is then presented, together with an explanation of changes made when revising the list. (who.int)
Sodium1
  • The pH control achieved by sodium citrate, either as an excipient in tablets or an additive during compounding, improved drug stability. (ijpc.com)
Chemical1
  • Redwood Bioscience is developing a precision protein-chemical engineering technology to produce next-generation antibody-drug conjugates and other semi-synthetic biotherapeutics. (catalent.com)
Evaluate1
  • To evaluate the effect on drug stability, pH modifiers were added to a suspension. (ijpc.com)
Drug Cuts Tardive Dyskinesia in Psychiatric Patients
Drug Cuts Tardive Dyskinesia in Psychiatric Patients (medscape.com)
Browsing by Subject Drug Stability
Browsing by Subject "Drug Stability" (extranet.who.int)
Promoting Health Equity | Drug Overdose | Injury Center
Promoting Health Equity | Drug Overdose | Injury Center (cdc.gov)
Browsing Technical documents by Subject Drug Stability
Browsing Technical documents by Subject "Drug Stability" (extranet.who.int)
Mandol (Cefamandole): Uses, Dosage, Side Effects, Interactions, Warning
Mandol (Cefamandole): Uses, Dosage, Side Effects, Interactions, Warning (rxlist.com)
The Effectiveness of Core Stability Exercises - Full Text View - ClinicalTrials.gov
The Effectiveness of Core Stability Exercises - Full Text View - ClinicalTrials.gov (clinicaltrials.gov)
Thoracoabdominal Aorta Replacement | Main Line Health
Thoracoabdominal Aorta Replacement | Main Line Health (mainlinehealth.org)
Search
Search (apps.who.int)
In the Spotlight June 2007
In the Spotlight June 2007 (pharmtech.com)
Article Metrics] Multi-access drug delivery network and stability | IJN
Article Metrics] Multi-access drug delivery network and stability | IJN (dovepress.com)
Drug shortages jeopardize the lives of children with cancer - STAT
Drug shortages jeopardize the lives of children with cancer - STAT (statnews.com)
Nanoemulsion: an advanced mode of drug delivery system | SpringerLink
Nanoemulsion: an advanced mode of drug delivery system | SpringerLink (link.springer.com)
Specialist Stability job with Amgen | 2628774
Specialist Stability job with Amgen | 2628774 (biospace.com)
ECCD - Course Hero
ECCD - Course Hero (coursehero.com)
Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment
Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment (medscape.com)
Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment
Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment (medscape.com)
Bispecific antibodies: a mechanistic review of the pipeline | Nature Reviews Drug Discovery
Bispecific antibodies: a mechanistic review of the pipeline | Nature Reviews Drug Discovery (nature.com)
Custom Research Labs Inc. - 616184 - 07/08/2022 | FDA
Custom Research Labs Inc. - 616184 - 07/08/2022 | FDA (fda.gov)
Frontiers | Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic...
Frontiers | Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic... (frontiersin.org)
Corpse Degradation of Farmed Fish Increases the Abundance of Antibiotic Resistance Genes but Exhibits the Temporal Stability |...
Corpse Degradation of Farmed Fish Increases the Abundance of Antibiotic Resistance Genes but Exhibits the Temporal Stability |... (researchsquare.com)
Genentech's glyco-engineered antibody to succeed Rituxan | Nature Biotechnology
Genentech's glyco-engineered antibody to succeed Rituxan | Nature Biotechnology (nature.com)
Stability of CPM in Two Musculoskeletal Pain Models
Stability of CPM in Two Musculoskeletal Pain Models (medscape.com)
Platinol-AQ (Cisplatin Injection): Uses, Dosage, Side Effects, Interactions, Warning
Platinol-AQ (Cisplatin Injection): Uses, Dosage, Side Effects, Interactions, Warning (rxlist.com)
Mixed Reviews on Rotational Stability of Toric IOLs
Mixed Reviews on Rotational Stability of Toric IOLs (medscape.com)
Plaque Stability on Statins Bolstered by 'Good' Calcification
Plaque Stability on Statins Bolstered by 'Good' Calcification (medscape.com)
Closed Kinetic Chain Upper Extremity Stability Test
Closed Kinetic Chain Upper Extremity Stability Test (medscape.com)
FDA OKs Attain Stability Quad Active-Fixation Left Heart Lead
FDA OKs Attain Stability Quad Active-Fixation Left Heart Lead (medscape.com)