Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Polyethylenes: Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.Polyethylene: A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.Glycols: A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.Ethylene Glycols: An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.Cathartics: Agents that are used to stimulate evacuation of the bowels.Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)Crystallization: The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Chemical Precipitation: The formation of a solid in a solution as a result of a chemical reaction or the aggregation of soluble substances into complexes large enough to fall out of solution.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Hydrogels: Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Liposomes: Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.Particle Size: Relating to the size of solids.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.Antigen-Antibody Complex: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.Excipients: Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.X-Ray Diffraction: The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Hip Prosthesis: Replacement for a hip joint.Tannins: Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS). The two main types are HYDROLYZABLE TANNINS and CONDENSED TANNINS. Historically, the term has applied to many compounds and plant extracts able to render skin COLLAGEN impervious to degradation. The word tannin derives from the Celtic word for OAK TREE which was used for leather processing.Lactulose: A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)Polyethylene Terephthalates: Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.Surface-Active Agents: Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.Therapeutic Irrigation: The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.Laxatives: Agents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION.Propylene Glycols: Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.Solvents: Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)Colonoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the colon.Anhydrides: Chemical compounds derived from acids by the elimination of a molecule of water.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Magnesium Oxide: Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.Protoplasts: The protoplasm and plasma membrane of plant, fungal, bacterial or archaeon cells without the CELL WALL.Dextrans: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.Molecular Weight: The sum of the weight of all the atoms in a molecule.Adsorption: The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.Polyglactin 910: A polyester used for absorbable sutures & surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.Nephelometry and Turbidimetry: Chemical analysis based on the phenomenon whereby light, passing through a medium with dispersed particles of a different refractive index from that of the medium, is attenuated in intensity by scattering. In turbidimetry, the intensity of light transmitted through the medium, the unscattered light, is measured. In nephelometry, the intensity of the scattered light is measured, usually, but not necessarily, at right angles to the incident light beam.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Micelles: Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.Hydrogel: A network of cross-linked hydrophilic macromolecules used in biomedical applications.Fecal Impaction: Formation of a firm impassable mass of stool in the RECTUM or distal COLON.Polyethyleneimine: Strongly cationic polymer that binds to certain proteins; used as a marker in immunology, to precipitate and purify enzymes and lipids. Synonyms: aziridine polymer; Epamine; Epomine; ethylenimine polymer; Montrek; PEI; Polymin(e).Poloxamer: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)Chromium Alloys: Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Complement Activating Enzymes: Enzymes that activate one or more COMPLEMENT PROTEINS in the complement system leading to the formation of the COMPLEMENT MEMBRANE ATTACK COMPLEX, an important response in host defense. They are enzymes in the various COMPLEMENT ACTIVATION pathways.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Nanocapsules: Nanometer-sized, hollow, spherically-shaped objects that can be utilized to encapsulate small amounts of pharmaceuticals, enzymes, or other catalysts (Glossary of Biotechnology and Nanobiotechnology, 4th ed).Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)Cell Fusion: Fusion of somatic cells in vitro or in vivo, which results in somatic cell hybridization.Kinetics: The rate dynamics in chemical or physical systems.Osmosis: Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane.Osmotic Pressure: The pressure required to prevent the passage of solvent through a semipermeable membrane that separates a pure solvent from a solution of the solvent and solute or that separates different concentrations of a solution. It is proportional to the osmolality of the solution.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Pharmaceutic Aids: Substances which are of little or no therapeutic value, but are necessary in the manufacture, compounding, storage, etc., of pharmaceutical preparations or drug dosage forms. They include SOLVENTS, diluting agents, and suspending agents, and emulsifying agents. Also, ANTIOXIDANTS; PRESERVATIVES, PHARMACEUTICAL; COLORING AGENTS; FLAVORING AGENTS; VEHICLES; EXCIPIENTS; OINTMENT BASES.Nanomedicine: The branch of medicine concerned with the application of NANOTECHNOLOGY to the prevention and treatment of disease. It involves the monitoring, repair, construction, and control of human biological systems at the molecular level, using engineered nanodevices and NANOSTRUCTURES. (From Freitas Jr., Nanomedicine, vol 1, 1999).Pharmaceutical Vehicles: A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)Cryoprotective Agents: Substances that provide protection against the harmful effects of freezing temperatures.Dendrimers: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Povidone: A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.Barbital: A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression.Serum Albumin, Bovine: Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)Phosphatidylethanolamines: Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and ethanolamine and 2 moles of fatty acids.Emulsions: Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Tissue Adhesives: Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.Acetabulum: The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).Cellulose, Oxidized: A cellulose of varied carboxyl content retaining the fibrous structure. It is commonly used as a local hemostatic and as a matrix for normal blood coagulation.Methods: A series of steps taken in order to conduct research.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Viscosity: The resistance that a gaseous or liquid system offers to flow when it is subjected to shear stress. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Arthroplasty, Replacement, Hip: Replacement of the hip joint.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Mannitol: A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.Half-Life: The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Blood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Intestinal Absorption: Uptake of substances through the lining of the INTESTINES.Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Senna Extract: Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.Metal Nanoparticles: Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Hypovolemia: An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).Spectroscopy, Fourier Transform Infrared: A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.Ethylene Oxide: A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)Picolines: A group of compounds that are monomethyl derivatives of pyridines. (From Dorland, 28th ed)Succinimides: A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet-tasting compounds that are used as chemical intermediates and plant growth stimulants.Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)Simethicone: A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.Polylysine: A peptide which is a homopolymer of lysine.Nanospheres: Spherical particles of nanometer dimensions.Polynucleotide Ligases: Catalyze the joining of preformed ribonucleotides or deoxyribonucleotides in phosphodiester linkage during genetic processes. EC 6.5.1.Osmolar Concentration: The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.Knee Prosthesis: Replacement for a knee joint.ChymotrypsinogenCross-Linking Reagents: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.DimethylformamidePhosphates: Inorganic salts of phosphoric acid.Complement C1q: A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.Calorimetry, Differential Scanning: Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.Gastrointestinal Transit: Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Diffusion: The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Lespedeza: A plant genus of the family FABACEAE.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Femur Head: The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)Skin Absorption: Uptake of substances through the SKIN.Polyglycolic Acid: A biocompatible polymer used as a surgical suture material.Chitosan: Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.Hydrophobic and Hydrophilic Interactions: The thermodynamic interaction between a substance and WATER.Zirconium: Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)Electrophoresis, Polyacrylamide Gel: Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.Orbital Implants: Rounded objects made of coral, teflon, or alloplastic polymer and covered with sclera, and which are implanted in the orbit following enucleation. An artificial eye (EYE, ARTIFICIAL) is usually attached to the anterior of the orbital implant for cosmetic purposes.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.Biological Processes: Biological activities and function of the whole organism in human, animal, microorgansims, and plants, and of the biosphere.Permeability: Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.Polymerization: Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.Countercurrent Distribution: A method of separation of two or more substances by repeated distribution between two immiscible liquid phases that move past each other in opposite directions. It is a form of liquid-liquid chromatography. (Stedman, 25th ed)Freezing: Liquids transforming into solids by the removal of heat.Organ Preservation Solutions: Solutions used to store organs and minimize tissue damage, particularly while awaiting implantation.Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Genes, araC: Regulatory genes which encode a cyclic AMP receptor protein required for L-arabinose utilization in E. coli. It is an example of positive control or regulation of gene expression in the bacterial operon.Centrifugation: Process of using a rotating machine to generate centrifugal force to separate substances of different densities, remove moisture, or simulate gravitational effects. It employs a large motor-driven apparatus with a long arm, at the end of which human and animal subjects, biological specimens, or equipment can be revolved and rotated at various speeds to study gravitational effects. (From Websters, 10th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Hip Joint: The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.Cell Line, Tumor: A cell line derived from cultured tumor cells.Gels: Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.Freeze Drying: Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Enema: A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Ostreidae: A family of marine mollusks in the class BIVALVIA, commonly known as oysters. They have a rough irregular shell closed by a single adductor muscle.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Emulsifying Agents: SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid.Hepatovirus: A genus of PICORNAVIRIDAE causing infectious hepatitis naturally in humans and experimentally in other primates. It is transmitted through fecal contamination of food or water. HEPATITIS A VIRUS is the type species.Butylene Glycols: 4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.Magnesium Hydroxide: An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Metabolic Clearance Rate: Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.Membranes, Artificial: Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.Chromatography, Gel: Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.Polymethacrylic Acids: Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.Catalase: An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Cell Membrane Permeability: A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Ammonium Sulfate: Sulfuric acid diammonium salt. It is used in CHEMICAL FRACTIONATION of proteins.
Granulocyte colony-stimulating factor
Insuficiència renal crònica - Viquipèdia, l'enciclopèdia lliure
Polyethylene glycol-electrolyte solution (PEG-ES): MedlinePlus Drug Information
Polyethylene Glycol-Electrolyte Solution (MoviPrep, Plenvu) - Drugs.com
Polyethylene Glycol 3350 Dosage Guide with Precautions - Drugs.com
Polyethylene Glycol 3350 With Electrolytes - Side Effects, Dosage, Interactions - Drugs - Everyday Health
Polymers | Free Full-Text | Transparent Low Molecular Weight Poly(Ethylene Glycol) Diacrylate-Based Hydrogels as Film Media for...
Amphiphilic drug persuaded collapse of polyvinylpyrrolidone and poly(ethylene glycol) chains: a dynamic light scattering study.
An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene...
Life Brand Clearlax Laxative Powder for Oral Solution Contains Polyethylene Glycol 3350 119g | Shoppers Drug Mart®
Balloon-Occluded Transcatheter Arterial Chemoembolization (b-TACE) for Hepatocellular Carcinoma Performed with Polyethylene...
Polyethylene Glycol 3350 And Electrolytes (Oral Route) Description and Brand Names - Mayo Clinic
Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma...
DailyMed - PEG-3350, SODIUM CHLORIDE, SODIUM BICARBONATE AND POTASSIUM CHLORIDE- polyethylene glycol 3350, sodium chloride,...
Peg-3350, potassium chloride, sodium bicarbonate, sodium chloride / polyethylene glycol 3350; potassium chloride; sodium...
Synthesis and drug release of star shape poly(benzyl L-aspartate)-b-poly(ethylene glycol) copolymers with POSS cores-何斌
Synthesis and characterization of methoxy poly(ethylene glycol)-O-chitosan-polyethylenimine as a noviral carrier for gene...
Mircera (Epoetin Beta And Methoxy Polyethylene Glycol) - Side Effects, Interactions, Uses, Dosage, Warnings | Everyday Health
MoviPrep, PlenVu (polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid) dosing, indications, interactions, adverse...
Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against...
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) - Full Text View - ClinicalTrials.gov
Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic...
Nanomaterials | Free Full-Text | Gold Rod-Polyethylene Glycol-Carbon Dot Nanohybrids as Phototheranostic Probes | HTML
Polyethylene Glycol 3350, Sodium And Potassium Salts (Oral Route) Description and Brand Names - Mayo Clinic
Methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa for anemia in non-dialysis-dependent CKD: a systematic review ...
Frontiers | Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential...
Efficacy of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) Compared to Interferon Alfa-2B in Participants With...
Patent WO2012162019A1 - Thiobis phenolic antioxidant/polyethylene glycol blends - Google Patents
Polyethylene Glycol/electrolyte (Colyte, GoLYTELY) | Davis's Drug Guide
November 2017 - When do the patents on POLYETHYLENE GLYCOL 3350; POTASSIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE;...
SUNMARK CLEARLAX (polyethylene glycol 3350 powder, for solution) | Healthgrades.com
Starting polyethylene glycol-electrolyte solutionTaking polyethylene glycMirceraHydrophilicGolytelyInteract with polyethylene glycol-electrolyte solution2019PolymersMiraLaxNanoparticlesElectrolyteDevelopment of Polyethylene GlycolConstipationDosageMethoxy polyethylene glycolElectrolytes for Oral SolutionPolymerHydrogelsBowel3350 comesLaxativesPEGsDavis's Drug GuideLactic acidPropylene GlycolLaxative solutionTake polyethylenePreparationSodium bicarbonateEncapsulationChitosanDavis-Drug-GuideEfficacy of a novelMacrogolInteractionsLactuloseClinicalErythropoiesis-stimulCopolymerTumorEtherEthylene oxideMedicationPolyalkylenePhenolicCyclodextrinPhospholipid
Starting polyethylene glycol-electrolyte solution1
- Do not take other drugs within 1 hour of starting polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
Taking polyethylene glyc2
- If you become pregnant while taking polyethylene glycol 3350, call your doctor. (medlineplus.gov)
- What should I avoid while taking polyethylene glycol 3350? (mymedsbuy.com)
Mircera3
- On June 7, 2018, the Food and Drug Administration approved methoxy polyethylene glycol-epoetin beta (Mircera, Vifor Pharma Inc.) for the treatment of pediatric patients 5 to 17 years of age on hemodialysis who are converting from another ESA after. (medworm.com)
- Mircera (methoxy polyethylene glycol-epoetin beta) is an erythropoiesis-stimulating agent (ESA). (centerwatch.com)
- Mircera belongs to a group of drugs called erythropoiesis-stimulating agent (ESA). (rxwiki.com)
Hydrophilic5
- Using an in vitro guinea pig spinal cord injury model, we have shown that polyethylene glycol (PEG), a hydrophilic polymer, can significantly accelerate and enhance the membrane resealing process to restore membrane integrity following controlled compression. (nih.gov)
- Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. (sigmaaldrich.com)
- 6-8 Among these materials poly(ethylene glycol) (PEG) is a widely used and thoroughly studied hydrophilic protein repelling polymer. (rsc.org)
- The development of liposomes coated with the hydrophilic polymer polyethylene glycol (PEG) greatly broadened the application of liposomes ( Woodle and Lasic, 1992 ). (aspetjournals.org)
- The nanoparticle's "corona" can be functionalized with hydrophilic polymers, targeting molecules, therapeutic Drugs, and image contrast agents. (scirp.org)
Golytely5
- Studies on animal model have suggested that polyethylene glycol 3350-electrolyte solution (GOLYTELY) is effective in clearing gut bacteria and reducing the ammoniagenesis in colon. (clinicaltrials.gov)
- Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. (clinicaltrials.gov)
- This study is being done to find out if the laxative polyethylene glycol (also known as GoLYTELY® or Miralax®) can treat your hepatic encephalopathy (confusion due to your liver disease and/or cirrhosis) better and/or more safely than lactulose (another laxative). (clinicaltrials.gov)
- In this study, the investigators will evaluate if polyethylene glycol (GoLYTELY®) is more effective than lactulose on neurocognition (memory and thinking skills) and determine if it decreases the hospital stay. (clinicaltrials.gov)
- Polyethylene glycol electrolyte solution ( colyte ® , GoLYTELY ® , MoviPrep ® , NuLYTELY ® , TriLyte ® ) is a prescription medication licensed to empty the bowel before certain intestinal procedures, including a colonoscopy or a barium enema x-ray examination. (emedtv.com)
Interact with polyethylene glycol-electrolyte solution2
- This is not a list of all drugs or health problems that interact with polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Other drugs may interact with polyethylene glycol electrolyte solution, including prescription and over-the-counter medicines, vitamins, and herbal products. (everydayhealth.com)
20191
- 2019. https://www.drugguide.com/ddo/view/Davis-Drug-Guide/51622/all/polyethylene_glycol_electrolyte. (drugguide.com)
Polymers7
- We have studied the interaction between an amphiphilic drug, amitriptyline hydrochloride (AMT), and neutral polymers, polyvinylpyrrolidone (PVP) and poly(ethylene glycol) (PEG), using the dynamic light scattering (DLS) technique. (biomedsearch.com)
- Sterically stabilized liposome is characterized by a surface coating of polyethylene glycol (PEG) or other polymers that can reduce opsonization of the liposome by plasma proteins. (aacrjournals.org)
- Herein, a simple centrifugal spinning without the drawbacks of electrospinning was applied to fabricate polyethylene glycol-based PCM fibres with nano-SiC as a highly conductive filler, polyacrylonitrile as the supporting material, and N,N-dimethylformamide as the solvent to dissolve the polymers. (medworm.com)
- Polyethylene glycol (PEG) and related polymers (PEG phospholipid constructs) are often sonicated when used in biomedical applications. (wikipedia.org)
- New York, NY -- ( SBWIRE ) -- 12/08/2016 -- Polyethylene glycol (PEG) is one of the most frequently used non-ionic polymers in polymer-based drug delivery and other bioactivities. (sbwire.com)
- The existent scientific literature testifies for the various applications of polymers derived from polyethylene glycol (PEGs). (sbwire.com)
- Polyethylene glycol (PEG) is a family of long chain polymers attached to a glycerine backbone. (novusbio.com)
MiraLax3
- Taking miralax (polyethylene glycol) cause low potassium? (healthtap.com)
- Is it safe to take vitamin C supplements of 250mg with Propranolol, Levothyroxine and Miralax (polyethylene glycol)? (healthtap.com)
- Miralax ( polyethylene glycol ) dosed at 17 gm/day( a heaping tablespoon in 4-8 ounces of fluid) max 34gm/day. (healthtap.com)
Nanoparticles20
- Antibacterial activity of silver nanoparticles coated with different functionalizing agents i.e., polyethylene glycol, tween 80 and sodium dodecyl sulphate were evaluated on both normal and multi-drug resistant strains of bacteria. (ingentaconnect.com)
- Among these, poly- ethylene glycol coated nanoparticles were most effective in killing all the bacterial strains which includes Escherichia coli DH5 α , Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus and multi-drug resistant clinical isolates of Shigella spp . (ingentaconnect.com)
- The minimum inhibitory concentration of polyethylene glycol coated silver nanoparticles was also less compared to the other two sets of nanoparticles. (ingentaconnect.com)
- Consistence with that polyethylene glycol coated nanoparticles produced more intracellular reactive oxygen species in bacteria. (ingentaconnect.com)
- Thus our present investigation implicates the potential therapeutic use of silver nanoparticles as antibacterial agent particularly the polyethylene glycol coated one. (ingentaconnect.com)
- Long-circulating poly(ethylene glycol)-grafted gelatin nanoparticles customized for intracellular delivery of noscapine: preparation, in-vitro char. (nih.gov)
- Noscapine-enveloped gelatin nanoparticles and poly(ethylene glycol)-grafted gelatin nanoparticles were constructed and characterized. (nih.gov)
- It is to be noted that there is a 1.43-fold increase in the area under the curve up to the last sampling point for the noscapine-loaded poly(ethylene glycol)-grafted gelatin nanoparticles over the noscapine-loaded gelatin nanoparticles and a 13.09-fold increase over noscapine. (nih.gov)
- In this study, we developed poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles with variable molecular PEG weights (2, 10, or 20 kDa) to encapsulate antifungal amphotericin B (AmB) and to evaluate its in vitro efficacy in strains of Candida sp. (eurekaselect.com)
- Caroline Danziato Rodrigues, Diani Meza Casa, Luciana Facco Dalmolin, Luciana Erzinger Alves de Camargo, Najeh Maissar Khalil and Rubiana Mara Mainardes, "Amphotericin B-Loaded Poly(Lactide)-Poly(Ethylene Glycol)-Blend Nanoparticles: Characterization and In Vitro Efficacy and Toxicity", Current Nanoscience (2013) 9: 594. (eurekaselect.com)
- Abstract 4505: Preparation and anti-tumor growth of polyethylene glycol-poly lactic acid block copolymers sorafenib nanoparticles. (aacrjournals.org)
- Polyethylene glycol-poly lactic acid block copolymers sorafenib nanoparticles were prepared with nanometer precipitation method. (aacrjournals.org)
- Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. (nih.gov)
- Iron oxide nanoparticles have found widespread applications in different areas including cell separation, drug delivery and as contrast agents. (nih.gov)
- Due to water insolubility and stability issues, nanoparticles utilized for biological applications require coatings such as the commonly employed polyethylene glycol (PEG). (nih.gov)
- The anticancer drug doxorubicin (DOX) was encapsulated in the nanoparticles during preparation. (elsevier.com)
- Drug loading amounts and release behavior from prepared nanoparticles were investigated. (elsevier.com)
- The cell cytotoxicity of prepared nanoparticles was evaluated for receptor mediated drug delivery. (elsevier.com)
- Today nanoparticles based drug delivery or imaging agents are extremely being investigated as a very powerful tool in early diagnostics or treatment of different kinds of cancers including prostate malignancies. (scirp.org)
- Stereocomplexed poly(lactic acid)-poly(ethylene glycol) nanoparticles with dual-emissive boron dyes for tumor accumulation. (duke.edu)
Electrolyte42
- Polyethylene glycol-electrolyte solution (PEG-ES) is used to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) or barium enema (a test in which the colon is filled with a fluid and then x-rays are taken) so that the doctor will have a clear view of the walls of the colon. (medlineplus.gov)
- Polyethylene glycol-electrolyte solution (PEG-ES) comes as a powder to mix with water and take by mouth. (medlineplus.gov)
- What do I need to tell my doctor BEFORE I take Polyethylene Glycol-Electrolyte Solution? (drugs.com)
- If you have an allergy to polyethylene glycol or any other part of polyethylene glycol-electrolyte solution ( moviPrep , plenvu). (drugs.com)
- You must check to make sure that it is safe for you to take polyethylene glycol-electrolyte solution (moviPrep, plenvu) with all of your drugs and health problems. (drugs.com)
- What are some things I need to know or do while I take Polyethylene Glycol-Electrolyte Solution? (drugs.com)
- Tell all of your health care providers that you take polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- If you are over the age of 60, use polyethylene glycol-electrolyte solution (moviPrep, plenvu) with care. (drugs.com)
- You will need to talk about the benefits and risks of using polyethylene glycol-electrolyte solution (moviPrep, plenvu) while you are pregnant. (drugs.com)
- How is this medicine (Polyethylene Glycol-Electrolyte Solution) best taken? (drugs.com)
- Use polyethylene glycol-electrolyte solution (moviPrep, plenvu) as ordered by your doctor. (drugs.com)
- Take polyethylene glycol-electrolyte solution (moviPrep, plenvu) as your doctor has told you. (drugs.com)
- This includes when to take polyethylene glycol-electrolyte solution (moviPrep, plenvu), foods and drinks to avoid before the exam, and when to stop eating and drinking before the exam. (drugs.com)
- Talk with your doctor about how to take your other drugs with polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Mix with water as told before you take polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Drink clear liquids before, during, and after taking polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Do not eat solid food while taking polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Call your doctor if you are not able to finish polyethylene glycol-electrolyte solution (moviPrep, plenvu) before your exam. (drugs.com)
- Polyethylene glycol electrolyte solution is a laxative solution that increases the amount of water in the intestinal tract to stimulate bowel movements. (everydayhealth.com)
- Polyethylene glycol electrolyte solution is used to clean the bowel before colonoscopy, a barium x-ray, or other intestinal procedures. (everydayhealth.com)
- Polyethylene glycol electrolyte solution may also be used for purposes not listed in this medication guide. (everydayhealth.com)
- Polyethylene glycol electrolyte solution can cause dangerous or life-threatening side effects in people with these conditions. (everydayhealth.com)
- FDA pregnancy category C. It is not known whether polyethylene glycol electrolyte solution will harm an unborn baby. (everydayhealth.com)
- It is not known whether polyethylene glycol electrolyte solution passes into breast milk or if it could harm a nursing baby. (everydayhealth.com)
- Avoid taking other medications, vitamins, or mineral supplements within 1 hour before drinking polyethylene glycol electrolyte solution. (everydayhealth.com)
- Do not use other laxatives while using polyethylene glycol electrolyte solution unless your doctor has told you to. (everydayhealth.com)
- Polyethylene glycol electrolyte solution is a powder medicine that must be mixed with water before using it. (everydayhealth.com)
- polyethylene glycol/electrolyte is a topic covered in the Davis's Drug Guide . (drugguide.com)
- Davis's Drug Guide - OLD - USE 2.0 , www.drugguide.com/ddo/view/Davis-Drug-Guide/51622/all/polyethylene_glycol_electrolyte. (drugguide.com)
- What is the most important information I should know about polyethylene glycol electrolyte solution? (healthbanks.com)
- What should I discuss with my health care provider before taking polyethylene glycol electrolyte solution? (healthbanks.com)
- How should I take polyethylene glycol electrolyte solution? (healthbanks.com)
- The first watery stool should appear within 1 hour after you start drinking polyethylene glycol electrolyte solution. (healthbanks.com)
- Polyethylene glycol electrolyte solution will produce watery diarrhea. (healthbanks.com)
- In most cases, at least 3 liters of polyethylene glycol electrolyte solution is needed for the full effect. (healthbanks.com)
- Throw away any polyethylene glycol electrolyte solution you have not used within 24 to 48 hours after it was mixed (follow directions for your specific brand of this medicine). (healthbanks.com)
- No research has been done to determine if polyethylene glycol electrolyte solution would pass through human breast milk. (emedtv.com)
- However, it's still important to consult your healthcare provider if you are thinking of breastfeeding while using polyethylene glycol electrolyte solution. (emedtv.com)
- Can Women Take Polyethylene Glycol Electrolyte Solution While Breastfeeding? (emedtv.com)
- Therefore, if you are nursing a child, talk with your healthcare provider before taking polyethylene glycol electrolyte solution. (emedtv.com)
- However, because polyethylene glycol electrolyte solution has not been studied in women who are breastfeeding, every potential problem cannot yet be ruled out. (emedtv.com)
- Polyethylene glycol (PEG) 3350 solution without added electrolytes is an odourless osmotic laxative, which, unlike other colonic lavage solutions, carries no risk of salt absorption and hence no risk of electrolyte imbalance. (cfp.ca)
Development of Polyethylene Glycol1
- Some of the new experiments being done in the field of research & development such as the development of polyethylene glycol hydrogels which are used as adhesives for wound healing, wound closure, regenerative medicine tool with dopamine, tissue models and cell cultures will lead to opportunities for the polyethylene glycol market. (sbwire.com)
Constipation5
- Polyethylene glycol 3350 is used to treat occasional constipation. (medlineplus.gov)
- Polyethylene glycol 3350 is an osmotic laxative used for the treatment of occasional constipation in adults. (patientslikeme.com)
- Polyethylene glycol 3350 is a laxative solution, a completely different way to treat constipation. (mymedsbuy.com)
- Polyethylene glycol 3350 is used as a laxative to treat occasional constipation or irregular bowel movements. (mymedsbuy.com)
- Is polyethylene glycol safe and effective for chronic constipation in children? (bmj.com)
Dosage1
- Mahato, Ram I. (Dosage forms and drug delivery systems. (freepatentsonline.com)
Methoxy polyethylene glycol17
- Epoetin beta and methoxy polyethylene glycol is a combination medicine used to treat anemia (lack of red blood cells) and to reduce the need for blood cell transfusions. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol is used to treat anemia caused by chronic kidney disease in adults, or in children at least 5 years old who are on hemodialysis. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol may increase tumor growth or decrease survival time in people with certain types of cancer. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol should not be used to take the place of an emergency blood cell transfusion. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol may also be used for purposes not listed in this medication guide. (everydayhealth.com)
- Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using epoetin beta and methoxy polyethylene glycol. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol is injected under the skin or given as an infusion into a vein. (everydayhealth.com)
- Different reviews have focused on evaluating the safety and efficacy of methoxy polyethylene glycol-epoetin beta (MPG-EPO), a continuous erythropoietin receptor activator, in CKD patients regardless of dialysis dependency and others have studied this novel agent exclusively in CKD patients receiving dialysis. (springer.com)
- Information about drug Epoetin Beta-Methoxy Polyethylene Glycol includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. (medindia.net)
- The generic Epoetin Beta-Methoxy Polyethylene Glycol is manufactured by one company. (medindia.net)
- Medindia's drug directory has currently 55 Brands of Epoetin Beta-Methoxy Polyethylene Glycol listed . (medindia.net)
- Epoetin beta-methoxy polyethylene glycol(Epogen) generic is an erythropoiesis-stimulating agent, prescribed for anemia in people with chronic kidney failure. (medindia.net)
- Emergency Central , emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/109352/all/methoxy_polyethylene_glycol_epoetin_beta. (unboundmedicine.com)
- In this work we study the influence of PEG concentration in mixed 1,2-dimyristoyl- sn-glycero -3-phosphoethanolamine (DMPE) and 1,2-dimyristoyl- sn-glycero -3-phosphoethanol-amine- N -[methoxy(polyethylene glycol)-(DMPE-PEG2000) phospholipid monolayers on both the amount and the orientational ordering extent of the adsorbed proteins. (rsc.org)
- This study assessed the long-term efficacy, safety, and tolerability of intravenous (iv) or subcutaneous (sc) methoxy polyethylene glycol-epoetin beta in chronic kidney disease patients with renal anemia. (druglib.com)
- Eligible patients were those who were receiving stable maintenance therapy with methoxy polyethylene glycol-epoetin beta or erythropoiesis stimulating agents (ESAs) in Phase II or III clinical studies. (druglib.com)
- They continued to receive methoxy polyethylene glycol-epoetin beta or comparator ESAs at the same weekly dose and by the same route of administration (sc or iv) as in the qualifying studies. (druglib.com)
Electrolytes for Oral Solution1
- Polyethylene Glycol 3350 and Electrolytes for Oral Solution [package insert]. (emedtv.com)
Polymer2
- 11. The method of claim 1 , wherein the polymer backbone is selected from the group consisting of linear or branched poly(alkylene oxide), linear or branched poly(vinyl pyrrolidone), linear or branched poly(vinyl alcohol), linear or branched polyoxazoline, and linear or branched poly(acryloylmorpholine). (google.com)
- PLGA or poly (lactic-co-glycolic acid) could be a polymer that is employed during a host of Food and Drug Administration (FDA) approved therapeutic devices, thanks to its biodegradability and biocompatibility. (scirp.org)
Hydrogels8
- Hydrogels have shown a great potential as materials for drug delivery systems thanks to their usually excellent bio-compatibility and their ability to trap water-soluble organic molecules in a porous network. (mdpi.com)
- In this study, poly(ethylene glycol)-based hydrogels containing a model dye were synthesized by ultraviolet (UV-A) photopolymerization of low-molecular weight macro-monomers and the material properties (dye release ability, transparency, morphology, and polymerization kinetics) were studied. (mdpi.com)
- In recent years, macroporous hydrogels are sought after for a wide range of tissue engineering and drug delivery applications. (aiche.org)
- In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. (ac.rs)
- The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. (ac.rs)
- ydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. (ac.rs)
- Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems. (ac.rs)
- This study presents a new strategy of tuning the encapsulation efficiency and the release rate of protein drugs from a PLGA microsphere by filling the hollow core of the microsphere with poly(ethylene glycol) (PEG) hydrogels of varying cross-linking density. (illinois.edu)
Bowel8
- It may take 2 to 4 days for polyethylene glycol 3350 to produce a bowel movement. (medlineplus.gov)
- The polyethylene glycol (PEG) and electrolytes solution is used to cleanse the colon (bowel) before certain medical tests (eg, colonoscopy, barium enema X-ray exam) or colon surgery. (mayoclinic.org)
- The polyethylene glycol (PEG), sodium and potassium salts solution is used to cleanse the colon (bowel) before a medical test (eg, colonoscopy). (mayoclinic.org)
- Background - Polyethylene glycol-based bowel preparations (PEGBPs) are widely perceived as safe and effective alternatives to oral sodium phosphate for bowel cleansing prior to colonoscopy. (ices.on.ca)
- Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. (healthtap.com)
- You should not use polyethylene glycol 3350 if you have a bowel obstruction or intestinal blockage. (mymedsbuy.com)
- You should not use this medicine if you are allergic to polyethylene glycol, or if you have a bowel obstruction or intestinal blockage. (mymedsbuy.com)
- Polyethylene glycol 3350 should produce a bowel movement within 1 to 3 days of using the medication. (mymedsbuy.com)
3350 comes2
- Polyethylene glycol 3350 comes as a powder to be mixed with a liquid and taken by mouth. (medlineplus.gov)
- Polyethylene glycol 3350 comes in powder form, which is dissolved in water before use. (emedtv.com)
Laxatives2
- Polyethylene glycol 3350 is in a class of medications called osmotic laxatives. (medlineplus.gov)
- Increased manufacturing of eye drops and laxatives coupled with the growth of pharmaceutical industry has increased the use of polyethylene glycol as a solvent which will drive the growth for polyethylene glycol market in future. (sbwire.com)
PEGs2
- Solid dispersions of 10% w/w griseofulvin in different polyethylene glycols (PEGs) with or without incorporation of alkali dodecyl sulphates (MDS) were prepared by the melting method. (diva-portal.org)
- PEGs and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. (wikipedia.org)
Davis's Drug Guide3
- Davis's Drug Guide for Nurses App + Web from F.A. Davis and Unbound Medicine covers 5000+ trade name and generic drugs. (drugguide.com)
- In Davis's Drug Guide (16th edition). (drugguide.com)
- Hi my name is I am interested in setting up a Davis's Drug Guide site license for my institution. (drugguide.com)
Lactic acid1
- Methods:Polyethylene glycol-poly lactic acid block copolymers were synthesized with ring-opening polymerization technique as drug carrier material. (aacrjournals.org)
Propylene Glycol1
- The introduction of propylene glycol (PG) units, pure and mixed with ethylene glycol (EG) pendant chains, can additionally tune the characteristics of such gels. (ac.rs)
Laxative solution1
- for more details on how polyethylene glycol 3350 works in this laxative solution to prep the bowels for a colonoscopy and other gastrointestinal procedures. (emedtv.com)
Take polyethylene1
- Take polyethylene glycol 3350 exactly as directed. (medlineplus.gov)
Preparation3
- We describe the preparation of organic semiconducting nanofibers comprising a crystalline poly(di-n-hexylfluorene) core and a solvated, segmented corona consisting of polyethylene glycol in the center and polythiophene at the ends. (medworm.com)
- The use of levo-ornidazole in the preparation of anti-parasitic infection drug is provided. (freepatentsonline.com)
- It is demonstrated that levo-ornidazole is superior to dextro-ornidazole and racemic ornidazole in the therapeutic action against parasitization (especially trichomonas vaginalis infection and cecal amoeba infection), and thus it is more practicable to formulate L-ornidazole as anti-parasitic infection drugs, and particularly as drug preparations which are suitable for clinical uses, including oral preparation, intravenous preparation and vaginal preparation. (freepatentsonline.com)
Sodium bicarbonate1
- NDA 090019 describes PEG-3350, POTASSIUM CHLORIDE, SODIUM BICARBONATE, SODIUM CHLORIDE , which is a drug marketed by Mylan , Novel Labs Inc , Strides Pharma , and Breckenridge Pharm , and is included in four NDAs. (drugpatentwatch.com)
Encapsulation3
- The drug loading content and encapsulation efficiency increased with increasing the chain length of PBLA blocks. (polymer.cn)
- However, their use is often plagued by limited controllability of encapsulation efficiency, initial burst, and release rate of drug molecules, which cause unsatisfactory outcomes and several side effects including inflammation. (illinois.edu)
- The resulting PEG-PLGA core-shell microspheres exhibited (1) increased encapsulation efficiency, (2) decreased initial burst, and (3) a more sustained release of protein drugs, as the cross-linking density of the PEG gel core was increased. (illinois.edu)
Chitosan4
- A novel water-soluble chitosan (CS) derivative３methoxy poly(ethylene glycol)-O-chitosan- polyethylenimine(mPEG-O-CS-PEI), was synthesized by grafting polycationic polyethylenimine (PEI) and methoxy poly (ethylene glycol) (mPEG) onto chitosan, the copolymer was characterized and confirmed by 1H-NMR and FT-IR spectra. (nsti.org)
- Among the chitosan derivatives, cyclodextrin-grafted chitosan and poly(ethylene glycol)-grafted chitosan are excellent candidates for a range of biomedical, environmental decontamination, and industrial purposes. (frontiersin.org)
- This work discusses modifications including chitosan with attached cyclodextrin and poly(ethylene glycol), and the main applications of these chitosan derivatives in the biomedical field. (frontiersin.org)
- Among the diverse developing nanomaterials, biocompatible biodegradable dendrimers and chitosan or PLGA (Poly Lactic-co-Glycolic Acid) derivatives are more considered due to their safer profiles. (scirp.org)
Davis-Drug-Guide2
- Davis Drug Guide PDF. (drugguide.com)
- Medicine Central, im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/51621/all/polyethylene_glycol. (unboundmedicine.com)
Efficacy of a novel2
- This paper investigates in vivo efficacy of a novel drug eluting paste in glioblastoma. (nottingham.ac.uk)
- The authors prospectively evaluated the safety and efficacy of a novel polyethylene glycol (PEG) hydrogel sealant in patients undergoing elective cranial surgery with documented cerebrospinal fluid (CSF) leakage after sutured dural repair. (thejns.org)
Macrogol2
- Polyethylene glycol 450 lauryl ether is also known as Macrogol Lauril Ether . (e-lactancia.org)
- Macrogol, used as a laxative, is a form of polyethylene glycol. (wikipedia.org)
Interactions5
- The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (drugs.com)
- However, the presence of large molecules such as PEG on the liposomal surface may reduce the interactions of liposomes with cells and hinder entry of liposomes into the tumor tissue (11 , 12) , thereby possibly reducing the accumulation of liposomal drugs in the tumor tissue. (aacrjournals.org)
- Once again, would suggest that your pharmacist should have a computerized program that lists all drug interactions and therefore should be able to help you out. (healthtap.com)
- No drug interactions have been studied by the manufacturer. (rxwiki.com)
- Not all drug interactions are known or reported and new drug interactions are continually being reported. (rxwiki.com)
Lactulose3
- Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P. (clinicaltrials.gov)
- The purpose of this study is to evaluate whether the use of polyethylene glycol is superior and more safe in treating hepatic encephalopathy compared to lactulose and also to determine if treatment with polyethylene glycol will reduce the duration of hospital stay. (clinicaltrials.gov)
- Recently published study by Robert Rahimi, University of Texas Southwestern Medical Center found that polyethylene glycol is more effective in improving HE over the first 24 hours compared to lactulose and also may reduce duration of hospital stay. (clinicaltrials.gov)
Clinical5
- Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns. (semanticscholar.org)
- These regimens, though effective, do not completely eliminate HIV and the development of drug resistance is a major clinical problem. (clinicaltrials.gov)
- As you have not prescribed this drug earlier, you want to appraise the evidence before using it in your clinical practice. (bmj.com)
- Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. (cancer.gov)
- Drug information typically includes the drug name, approval status, indication of use, and clinical trial results. (centerwatch.com)
Erythropoiesis-stimul1
- The recommended initial dose of the drug for subjects not receiving erythropoiesis-stimulating agents (ESAs) is .6 mcg/kg body weight administered as a single IV or SC injection once every two weeks. (centerwatch.com)
Copolymer2
- Firstly, the block copolymer poly(benzyl L-aspartate)- b -poly(ethylene glycol) (PBLA- b -PEG) was synthesized via ring-opening polymerization of β-benzyl L-aspartate-N-carboxyanhydride (BLA-NCA) with α-Methoxy-ω-aminopoly(ethylene glycol) (mPEG-NH 2 ) as a macroinitiator. (polymer.cn)
- The NPs were created by means of stereocomplexation using a methoxy-terminated polyethylene glycol and poly(D-lactide) (mPEG-PDLA) block copolymer combined with iodide-substituted difluoroboron dibenzoylmethane-poly(L-lactide) (BF2dbm(I)PLLA). (duke.edu)
Tumor2
- At a dose of 10 mg/kg, although both liposomal groups were better than the free drug group in terms of clinically relevant parameters, including toxicity, tumor shrinkage, and survival, there was no difference between the two liposomal drug groups. (aacrjournals.org)
- Dr. Dewhirst has research interests in tumor hypoxia, angiogenesis, hyperthermia and drug transport. (duke.edu)
Ether3
- Polyethylene glycol 450 lauryl ether and breastfeeding. (e-lactancia.org)
- We do not have alternatives for Polyethylene glycol 450 lauryl ether . (e-lactancia.org)
- Different forms of PEG are also available, depending on the initiator used for the polymerization process - the most common initiator is a monofunctional methyl ether PEG, or methoxypoly(ethylene glycol), abbreviated mPEG. (wikipedia.org)
Ethylene oxide1
- Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers. (wikipedia.org)
Medication1
- You can also visit the Food and Drug Administration (FDA) website ( http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm ) or the manufacturer's website to obtain the Medication Guide. (medlineplus.gov)
Polyalkylene5
- Thiobis phenolic antioxidants are efficiently dry or melt blended with a tree-resistant, crosslinkable polyethylene by first forming a blend, preferably a dry blend, of the antioxidant with a polyalkylene glycol (PAG), and then mixing the blend with the polyethylene. (google.ca)
- 1. An additive mixture comprising at least one thiobis phenolic antioxidant and at least one polyalkylene glycol (PAG) of a weight average molecular weight of at least 1,000. (google.ca)
- 15. A method of mixing a solid thiobis phenolic antioxidant with polyethylene, the method comprising the steps of (A) mixing the thiobis phenolic antioxidant with polyalkylene glycol (PAG) to form a blend, and (B) mixing the blend with polyethylene. (google.ca)
- The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. (google.com)
- 2. The method of claim 1, wherein said polyalkylene oxide is polyethylene glycol. (google.com)
Phenolic3
- The incorporation of thiobis phenolic antioxidant and PAG blend into polyethylene provides the PE with high oxidative induction time (OIT) which is a measure of the oxidative stability of the PE. (google.ca)
- 16. The method of Claim 15 in which the thiobis phenolic antioxidant and PAG are first dissolved in a common solvent to form the blend, and then the solvent is removed prior to mixing the blend with polyethylene. (google.ca)
- 17. The method of Claim 15 in which the thiobis phenolic antioxidant and PAG are melt-mixed to form the blend prior to mixing the blend with polyethylene. (google.ca)
Cyclodextrin2
- Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin. (sigmaaldrich.com)
- Thus the aqueous solubility of trans-resveratrol was investigated in the presence of growing concentrations of polyethylene glycol (PEG) or β-cyclodextrin (βCD) as solubilizing excipients. (sigmaaldrich.com)
Phospholipid2
- Could a liposomal drug composed of phospholipid with a higher transition temperature, such as DSPC (14 , 15 , 16) , even without PEG coating have antitumor activity equivalent to or better than a sterically stabilized one? (aacrjournals.org)
- We report here the influence of the poly(ethylene glycol) (PEG) grafting density in model phospholipid monolayers on the adsorption behavior of bovine serum albumin and human fibrinogen, not only with respect to the amount of adsorbed protein, but also its orientational ordering on the surface. (rsc.org)
