Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Polyethylenes: Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.Polyethylene: A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.Glycols: A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.Ethylene Glycols: An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.Cathartics: Agents that are used to stimulate evacuation of the bowels.Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)Crystallization: The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Chemical Precipitation: The formation of a solid in a solution as a result of a chemical reaction or the aggregation of soluble substances into complexes large enough to fall out of solution.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Hydrogels: Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Liposomes: Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.Particle Size: Relating to the size of solids.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.Antigen-Antibody Complex: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.Excipients: Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.X-Ray Diffraction: The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Hip Prosthesis: Replacement for a hip joint.Tannins: Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS). The two main types are HYDROLYZABLE TANNINS and CONDENSED TANNINS. Historically, the term has applied to many compounds and plant extracts able to render skin COLLAGEN impervious to degradation. The word tannin derives from the Celtic word for OAK TREE which was used for leather processing.Lactulose: A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)Polyethylene Terephthalates: Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.Surface-Active Agents: Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.Therapeutic Irrigation: The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.Laxatives: Agents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION.Propylene Glycols: Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.Solvents: Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)Colonoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the colon.Anhydrides: Chemical compounds derived from acids by the elimination of a molecule of water.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Magnesium Oxide: Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.Protoplasts: The protoplasm and plasma membrane of plant, fungal, bacterial or archaeon cells without the CELL WALL.Dextrans: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.Molecular Weight: The sum of the weight of all the atoms in a molecule.Adsorption: The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.Polyglactin 910: A polyester used for absorbable sutures & surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.Nephelometry and Turbidimetry: Chemical analysis based on the phenomenon whereby light, passing through a medium with dispersed particles of a different refractive index from that of the medium, is attenuated in intensity by scattering. In turbidimetry, the intensity of light transmitted through the medium, the unscattered light, is measured. In nephelometry, the intensity of the scattered light is measured, usually, but not necessarily, at right angles to the incident light beam.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Micelles: Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.Hydrogel: A network of cross-linked hydrophilic macromolecules used in biomedical applications.Fecal Impaction: Formation of a firm impassable mass of stool in the RECTUM or distal COLON.Polyethyleneimine: Strongly cationic polymer that binds to certain proteins; used as a marker in immunology, to precipitate and purify enzymes and lipids. Synonyms: aziridine polymer; Epamine; Epomine; ethylenimine polymer; Montrek; PEI; Polymin(e).Poloxamer: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)Chromium Alloys: Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Complement Activating Enzymes: Enzymes that activate one or more COMPLEMENT PROTEINS in the complement system leading to the formation of the COMPLEMENT MEMBRANE ATTACK COMPLEX, an important response in host defense. They are enzymes in the various COMPLEMENT ACTIVATION pathways.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Nanocapsules: Nanometer-sized, hollow, spherically-shaped objects that can be utilized to encapsulate small amounts of pharmaceuticals, enzymes, or other catalysts (Glossary of Biotechnology and Nanobiotechnology, 4th ed).Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)Cell Fusion: Fusion of somatic cells in vitro or in vivo, which results in somatic cell hybridization.Kinetics: The rate dynamics in chemical or physical systems.Osmosis: Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane.Osmotic Pressure: The pressure required to prevent the passage of solvent through a semipermeable membrane that separates a pure solvent from a solution of the solvent and solute or that separates different concentrations of a solution. It is proportional to the osmolality of the solution.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Pharmaceutic Aids: Substances which are of little or no therapeutic value, but are necessary in the manufacture, compounding, storage, etc., of pharmaceutical preparations or drug dosage forms. They include SOLVENTS, diluting agents, and suspending agents, and emulsifying agents. Also, ANTIOXIDANTS; PRESERVATIVES, PHARMACEUTICAL; COLORING AGENTS; FLAVORING AGENTS; VEHICLES; EXCIPIENTS; OINTMENT BASES.Nanomedicine: The branch of medicine concerned with the application of NANOTECHNOLOGY to the prevention and treatment of disease. It involves the monitoring, repair, construction, and control of human biological systems at the molecular level, using engineered nanodevices and NANOSTRUCTURES. (From Freitas Jr., Nanomedicine, vol 1, 1999).Pharmaceutical Vehicles: A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)Cryoprotective Agents: Substances that provide protection against the harmful effects of freezing temperatures.Dendrimers: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Povidone: A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.Barbital: A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression.Serum Albumin, Bovine: Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)Phosphatidylethanolamines: Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and ethanolamine and 2 moles of fatty acids.Emulsions: Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Tissue Adhesives: Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.Acetabulum: The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).Cellulose, Oxidized: A cellulose of varied carboxyl content retaining the fibrous structure. It is commonly used as a local hemostatic and as a matrix for normal blood coagulation.Methods: A series of steps taken in order to conduct research.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Viscosity: The resistance that a gaseous or liquid system offers to flow when it is subjected to shear stress. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Arthroplasty, Replacement, Hip: Replacement of the hip joint.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Mannitol: A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.Half-Life: The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Blood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Intestinal Absorption: Uptake of substances through the lining of the INTESTINES.Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Senna Extract: Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.Metal Nanoparticles: Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Hypovolemia: An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).Spectroscopy, Fourier Transform Infrared: A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.Ethylene Oxide: A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)Picolines: A group of compounds that are monomethyl derivatives of pyridines. (From Dorland, 28th ed)Succinimides: A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet-tasting compounds that are used as chemical intermediates and plant growth stimulants.Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)Simethicone: A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.Polylysine: A peptide which is a homopolymer of lysine.Nanospheres: Spherical particles of nanometer dimensions.Polynucleotide Ligases: Catalyze the joining of preformed ribonucleotides or deoxyribonucleotides in phosphodiester linkage during genetic processes. EC 6.5.1.Osmolar Concentration: The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.Knee Prosthesis: Replacement for a knee joint.ChymotrypsinogenCross-Linking Reagents: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.DimethylformamidePhosphates: Inorganic salts of phosphoric acid.Complement C1q: A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.Calorimetry, Differential Scanning: Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.Gastrointestinal Transit: Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Diffusion: The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Lespedeza: A plant genus of the family FABACEAE.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Femur Head: The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)Skin Absorption: Uptake of substances through the SKIN.Polyglycolic Acid: A biocompatible polymer used as a surgical suture material.Chitosan: Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.Hydrophobic and Hydrophilic Interactions: The thermodynamic interaction between a substance and WATER.Zirconium: Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)Electrophoresis, Polyacrylamide Gel: Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.Orbital Implants: Rounded objects made of coral, teflon, or alloplastic polymer and covered with sclera, and which are implanted in the orbit following enucleation. An artificial eye (EYE, ARTIFICIAL) is usually attached to the anterior of the orbital implant for cosmetic purposes.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.Biological Processes: Biological activities and function of the whole organism in human, animal, microorgansims, and plants, and of the biosphere.Permeability: Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.Polymerization: Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.Countercurrent Distribution: A method of separation of two or more substances by repeated distribution between two immiscible liquid phases that move past each other in opposite directions. It is a form of liquid-liquid chromatography. (Stedman, 25th ed)Freezing: Liquids transforming into solids by the removal of heat.Organ Preservation Solutions: Solutions used to store organs and minimize tissue damage, particularly while awaiting implantation.Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Genes, araC: Regulatory genes which encode a cyclic AMP receptor protein required for L-arabinose utilization in E. coli. It is an example of positive control or regulation of gene expression in the bacterial operon.Centrifugation: Process of using a rotating machine to generate centrifugal force to separate substances of different densities, remove moisture, or simulate gravitational effects. It employs a large motor-driven apparatus with a long arm, at the end of which human and animal subjects, biological specimens, or equipment can be revolved and rotated at various speeds to study gravitational effects. (From Websters, 10th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Hip Joint: The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.Cell Line, Tumor: A cell line derived from cultured tumor cells.Gels: Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.Freeze Drying: Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Enema: A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Ostreidae: A family of marine mollusks in the class BIVALVIA, commonly known as oysters. They have a rough irregular shell closed by a single adductor muscle.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Emulsifying Agents: SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid.Hepatovirus: A genus of PICORNAVIRIDAE causing infectious hepatitis naturally in humans and experimentally in other primates. It is transmitted through fecal contamination of food or water. HEPATITIS A VIRUS is the type species.Butylene Glycols: 4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.Magnesium Hydroxide: An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Metabolic Clearance Rate: Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.Membranes, Artificial: Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.Chromatography, Gel: Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.Polymethacrylic Acids: Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.Catalase: An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Cell Membrane Permeability: A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Ammonium Sulfate: Sulfuric acid diammonium salt. It is used in CHEMICAL FRACTIONATION of proteins.
Patel SS, Benfield P (Jun 1996). "New drug profile: pegaspargase (Polyethylene Glycol L-Asparaginase)". Clinical ... The drug is manufactured by Exelead, Inc. It is used in the treatment of acute lymphoblastic leukemia. PEGylation "UNM Cancer ... Drug Deliv. Rev. 55 (10): 1293-302. doi:10.1016/S0169-409X(03)00110-8. PMID 14499708. ...
Polyethylene glycol was chosen as the polymer. A team of Davis, Theodorus Van Es, Nicholas C. Palczuk, and Abraham Abuchowski ... a powerful and flexible strategy to improve the drug delivery". Current Drug Metabolism. 13 (1): 105-119. doi:10.2174/ ... Methoxy polyethylene glycol-epoetin beta (Mircera) - PEGylated form of erythropoietin to combat anemia associated with chronic ... is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called ...
"BestBETs: Is polyethylene glycol safe and effective for chro.." Retrieved 2007-09-06. Roerig JL, Steffen KJ, Mitchell JE, ... It has not been approved by the Food and Drug Administration for use in the United States, but it is in development by Shire ... Solutions of polyethylene glycol and electrolytes (sodium chloride, sodium bicarbonate, potassium chloride, and sometimes ... Di Palma JA, Cleveland MV, McGowan J, Herrera JL (2007). "A randomized, multicenter comparison of polyethylene glycol laxative ...
Biggers, K; Scheinfeldt, N (2008). "Pegloticase, a polyethylene glycol conjugate of uricase for the potential intravenous ... "FDA approves new drug for gout". FDA. September 14, 2010. Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, ... The drug is administered by infusion intravenously. It was developed by Savient Pharmaceuticals. In September 2010, the FDA ... These PEG chains consist of about 225 ethylene glycol units each (10 kg/mol PEG). Dalbeth, N; Merriman, TR; Stamp, LK (22 ...
"Highly extensible, tough, and elastomeric nanocomposite hydrogels from poly (ethylene glycol) and hydroxyapatite nanoparticles ... The best method of drug loading is dependent on the structures of the drug to be bound. Also, drug loading can occur as the ... Nanoparticles can generally carry drugs in two ways: drugs can either be bound to the outside of the nanoparticles or packed ... Depending on the method of inserting drugs into the material, for example, dissolved, encased, or attached, the drug carrier ...
... polyarylates and copolymers with poly(ethylene glycol)". Advanced Drug Delivery Reviews. 55 (4): 447-66. doi:10.1016/S0169-409X ... This characteristic can be taken advantage of and used to create new selective cancer-fighting drugs and to prevent cross- ... The remaining production of amino acids is used in the synthesis of drugs and cosmetics. Similarly, some amino acids ... Industrial uses include the production of drugs, biodegradable plastics, and chiral catalysts. The first few amino acids were ...
Polyethylene Glycol) studding the outside of the membrane. The PEG coating, which is inert in the body, allows for longer ... the drug will also be neutralized, allowing it to freely pass through a membrane. These liposomes work to deliver drug by ... "Specific targeting with poly (ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric ... Lipid bilayer Targeted drug delivery Azotosome Torchilin, V (2006). "Multifunctional nanocarriers". Advanced Drug Delivery ...
Gold nanoparticles in chemotherapy
To effectively target the malignant cells, the AuNPs were conjugated by polyethylene glycol, a process known as PEGylation. ... Gold nanoparticles that act as drug delivery systems in conjugation with chemotherapeutic drugs typically range in size from 10 ... Another way in which AuNPs can be used in cancer therapy is as agents for targeted drug delivery. Research shows that AuNPs can ... Drug vectorization requires greater specificity, and are synthesized within the single digit measurements ranging from 3-7 nm.[ ...
The polyethylene glycol coating results in preferential concentration of doxorubicin in the skin. However, this also results in ... Investigational Sarcoma Drug GPX-150 Gets Orphan Drug Designation. 2016 Archived 2016-01-24 at the Wayback Machine. "Drug ... Unlike Doxil, the Myocet liposome does not have a polyethylene glycol coating, and therefore does not result in the same rate ... There is a pegylated (polyethylene glycol coated) liposome-encapsulated form of doxorubicin, sold as Doxil. It was developed to ...
Polyethylene glycol (PEG) in a LISS solution removes water from the system and thus concentrates the antibodies present. PEG ... In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug. For example ... False-positive results may occur more frequently with the use of polyethylene glycol due to its strong agglutination ... Examples of potentiators include albumin, LISS (low ionic-strength saline) and PEG (polyethylene glycol). Potentiators are also ...
For example, radiolabeled polyethylene glycol coated hexadecylcyanoacrylate nanospheres targeted and accumulated in a rat ... Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB. Modalities for drug delivery/ ... Kreuter, Jörg (2014). "Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?". Advanced Drug ... Löscher, Wolfgang; Potschka, Heidrun (2005). "Drug resistance in brain diseases and the role of drug efflux transporters". ...
Nomenclature of monoclonal antibodies
An antibody can be PEGylated (attached to molecules of polyethylene glycol) to slow down its degradation by enzymes and to ... Adalimumab is a drug targeting TNF alpha. Its name can be broken down into ada-lim-u-mab. Therefore, the drug is a human ... This shows that the drug is a human monoclonal antibody acting against tumors. The name of benralizumab, a drug designed for ... "Drug Dictionary: Glembatumumab vedotin". National Cancer Institute. "ATC/DDD Classification (final)". WHO Drug Information. ...
... synthetic polymers such as polyethylene glycol, and carbon nanotubes. Antibody-drug conjugates such as Brentuximab vedotin and ... 18 (41). Gerber, HP; Senter, PD; Grewal, IS (2009). "Antibody drug-conjugates targeting the tumor vasculature: Current and ... and delivering drugs to targeted cells. Bioconjugation is a crucial strategy that links these modified biomolecules with ... ranging from the simple and nonspecific use of a fluorescent dye marker to the complex design of antibody drug conjugates. As a ...
Follicular dendritic cell sarcoma
Sharpe, Miriam; Easthope, Stephanie E.; Keating, Gillian M.; Lamb, Harriet M. (2002). "Polyethylene glycol-liposomal ... Although this drug still cannot strictly target cancer cells, cancer cells have a higher average turnover of microtubules ... Prednisone, the last drug in the CHOP combination therapy is a corticosteroid that acts as an immunosuppressant decreasing ... The more we know about acquired capabilities of cancer, the more we can target those pathways, put new drugs on the market, and ...
... which binds the drug and the antibody. Maleimides linked to polyethylene glycol chains are often used as flexible linking ... or a synthetic polymer such as polyethylene glycol. Human hemoglobin chemically modified with maleimide-polyethylene glycol is ... For instance, emerging promising targeted drug therapies, antibody-drug conjugates, are constituted of three main components: a ... Attaching the other end of the polyethylene chain to a bead or solid support allows for easy separation of protein from other ...
"Self-assembled targeted nanoparticles based on transferrin-modified eight-arm-polyethylene glycol-dihydroartemisinin conjugate ... Dihydroartemisinin is used to treat malaria, generally as a combination drug with piperaquine. In a systematic review of ... Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is ... Current Drug Targets. 7 (4): 407-21. doi:10.2174/138945006776359412. PMID 16611029. Cabello, Christopher M.; Lamore, Sarah D.; ...
Continuous erythropoietin receptor activator
Mircera is similar to the previous synthetic EPO drugs, except that it is connected to a chemical called polyethylene glycol ( ... Methoxy polyethylene glycol-epoetin beta had been approved by the European Commission in August 2007, and was made available in ... methoxy polyethylene glycol-epoetin beta) for the treatment of anemia in patients with chronic kidney disease, including in ... CERA has generally been well tolerated in clinical trials. Like all previous generations of EPO, the drug has ...
These include long-acting interferon bound to polyethylene glycol (pegylated interferon) and the oral nucleoside analogues. ... In the United States, herbal and dietary supplements - unlike pharmaceutical drugs - are unregulated by the Food and Drug ... These populations include people who are: Intravenous drug users (past or current) Intranasal illicit drug users HIV-positive ... and intravenous drug injection. A history of intravenous drug injection is the most important risk factor for chronic hepatitis ...
Bristol stool scale
In a randomised controlled study, the scale is used to study the response to two laxatives: Macrogol (polyethylene glycol) and ... in one study was also used to titrate the dose more finely than one drug (colestyramine) in subjects with diarrhoea and faecal ... Controlled Comparison of Low-Dose Polyethylene Glycol 3350 plus Electrolytes with Ispaghula Husk in the Treatment of Adults ... Controlled Comparison of Low-Dose Polyethylene Glycol 3350 plus Electrolytes with Ispaghula Husk in the Treatment of Adults ...
Network of Excellence for Functional Biomaterials
... such as polyethylene glycol (PEG), poly(lactic-co-glycolic acid) (PLGA), poly(lactic acid) (PLA), polyvinyl alcohol (PVA), ... NFB is continuously developing new technologies for use in gene delivery and drug delivery using a wide range of clinically ... NFB is also using natural and synthetic hollow microspheres to encapsulate anti-fibrotic drugs and incorporate them into ... NFB develops nano-fibrous meshes with well-defined nanotopography and drug loading capabilities to enhance functional repair. ...
... polyethylene glycol is linked to the interferon molecule to make the interferon last longer in the body. Approval for PEGylated ... These PEGylated drugs are injected once weekly, rather than administering two or three times per week, as is necessary for ... Both hepatitis B and hepatitis C are treated with IFN-α, often in combination with other antiviral drugs. Some of those treated ... For example, in January 2001, the Food and Drug Administration (FDA) approved the use of PEGylated interferon-alpha in the USA ...
... polyethylene glycol, hydrogels and glycerinated gelatin. The type of material used depends on the type of suppository, the type ... "Muse Suppository - Facts and Comparisons". Drugs.com. Retrieved 4 January 2013. Doyle, D., "Per Rectum: A History of Enemata", ... of drug and the conditions in which the suppository will be stored. In 1991, Abd-El-Maeboud and his colleagues conducted a ...
This is achieved by giving the patient large amounts of a polyethylene glycol solution. The osmotically balanced polyethylene ... Many drug molecules are made toxic in the liver, and the genetic variability of certain liver enzymes makes the toxicity of ... Its major uses are to treat ingestion of sustained release drugs, toxins not absorbed by activated charcoal (e.g., lithium, ... However, charcoal is ineffective against metals such as sodium, potassium, and lithium, and alcohols and glycols; it is also ...
1999). "In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized polyethylene glycol ... For prolonged drug delivery to the treatment site, implantation of these drug loaded artificial cells would be more cost ... When the poly-anionic cellulose sulphate solution is immersed in a second, poly-cationic solution (e.g. pDADMAC), a semi- ... The polymers used for islet microencapsulation are alginate, chitosan, polyethylene glycol (PEG), agarose, sodium cellulose ...
The conjugation of polyethylene glycol (PEG) chains to potential drug candidates extends the stability against proteases in ... polyethylene glycol) chains or reactive groups for further synthesis (see applications). The aldehyde tag is an artificial ... Rideout, D. (1994) Self-assembling drugs: a new approach to biochemical modulation in cancer chemotherapy. Cancer Invest. 12, ... and ketones as a chemical reporter in bioorthogonal applications has been applied in self-assembly of cell-lysing drugs, the ...
Polyethylene glycol (PEG) hydrogels Poly (2-hydroxyethyl methacrylate) (PHEMA) hydrogels Polyethylene glycol(PEG) polymers are ... Adhesion in a specifically targeted region will cause for a localized drug delivery and an increased concentration of the drug ... Smart hydrogels in drug delivery: Smart hydrogels are sensitive to stimuli such as changes in temperature or pH. Changes in the ... PEG hydrogels are not toxic to the body, do not elicit an immune response, and have been approved by the US Food and Drug ...
... polyethylene glycol polymers, custom dental splints Platelet transfusions (only if bleeding is severe; risk of platelet ... Dental hygiene lessens gingival bleeding Avoidance of antiplatelet agents such as aspirin and other anti-inflammatory drugs ( ... may be necessary if excessive or prolonged bleeding has caused anemia Hepatitis B vaccine Antifibrinolytic drugs such as ... alloimmunization) Recombinant factor VIIa, AryoSeven or NovoSeven FDA approved this drug for the treatment of the disease on ...
... phosphate ester of alkylaryloxy polyethylene glycol) ◦Methylbenzethonium chloride ◦Nonylphenoxypoly (ethyleneoxy) ethanoliodine ... In the US, triclosan is regulated as a pesticide by EPA and as a drug by FDA. EPA generally regulates uses on solid surfaces, ... Food and Drug Administration (2016) FDA issues final rule on safety and effectiveness of antibacterial soaps. Available at: ... Food and Drug Administration (17 June 1994). "Federal Register Notice: Tentative Final Monograph for OTC Healthcare Antiseptic ...
In this technique, drug particles are enveloped in a plasma membrane-bound vesicle. Folate is attached to polyethylene glycol ... Targeted drug therapy is advantageous because it deposits the drug at the specific location where it can be most useful in ... Leamon CP (December 2008). "Folate-targeted drug strategies for the treatment of cancer". Curr Opin Investig Drugs. 9 (12): ... While some drugs and radioimaging agents are delivered to cells as folate conjugates in a one-to-one folate-to-conjugate ratio ...
Polymers are used for the delivery of drugs and proteins. Some types of polymers being tested now are poly(ethylene glycol) ( ... Many enzymes in the body decompose the drug if the drug is taken by other means. The polymer-drug N-(2-Hydroxypropyl) ... Polymer-drug conjugates are drug molecules held up in polymer molecules. The polymer molecules are used as the delivery system ... "Targeted Drug Delivery by Novel Polymer-drug Conjugates Containing Linkers Cleavable by Disease-associated Enzymes." [email protected] ...
Calcium channel blocker
... and polyethylene glycol may be used to decontaminate the gut. Efforts for gut decontamination may be extended to within 8 hours ... He named this herbal drug "Zarnab" and used it as a cardiac remedy. This was the first known use of a calcium channel blocker ... through calcium channels. Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease ... Calcium Channel Antagonists". Poisoning & drug overdose (6th ed.). McGraw-Hill Medical. ISBN 978-0071668330. .. ...
... s are used in firefighting and pipelines (liquid drag reducing agents). Alkali surfactant polymers are used to ... The polyether groups often comprise ethoxylated (polyethylene oxide-like) sequences inserted to increase the hydrophilic ... Octaethylene glycol monododecyl ether. *Pentaethylene glycol monododecyl ether. Alkylphenol ethoxylates (APEs or APEOs). ...
"U.S. Food and Drug Administration. U.S. Food and Drug Administration. Retrieved 2 October 2015.. .mw-parser-output cite. ... Examples of lining materials include zinc oxide eugenol, zinc phosphate, glass ionomer cement, zinc poly-carboxylate and resin. ... Mercury has properties of a bacteriostatic agent whereas certain methacrylate polymers (for example TEGMA, triethylene glycol ... "Food and Drug Administration. Retrieved 19 April 2015.. *^ "Final opinion on dental amalgam". European Commission. 2 June 2015 ...
Polyethylene (PE) Polyethylene terephthalate (PET). Polyol. Polypropylene (PP). Polystyrene (PS). Styrene butadiene (SBR). ... ethylene glycol - via ethylene oxide hydration *engine coolant - ethylene glycol, water and inhibitor mixture ... Pharmaceutical drugs. Specialty and industrial chemicals. Specialty and industrial gases. Inks, dyes and printing supplies. ... polyethylene - polymerized ethylene; LDPE, HDPE, LLDPE. *ethanol - via ethylene hydration (chemical reaction adding water) of ...
Despite solubility in propylene glycol it is unlikely to replace water in saponificaction due to propylene glycol primary ... Page 168 in: The Detection of poisons and strong drugs. Author: Wilhelm Autenrieth. Publisher: P. Blakiston's son & Company, ... Common materials that are compatible with sodium hydroxide and often utilized for NaOH storage include: polyethylene (HDPE, ... a man who worked for drug cartels admitted disposing of over 300 bodies with it. Sodium hydroxide is a dangerous chemical ...
Certain additives, such as polyethylene glycol or polyethylenimine, can improve the aspect ratio of the ZnO nanowires. ... "U.S. Food and Drug Administration.. *^ Mitchnick, M. A.; Fairhurst, D.; Pinnell, S. R. (1999). "Microfine zinc oxide (Z-cote) ... 2004). "Photoprotection of poly(ethylene-naphthalate) by zinc oxide coating". Surface and Coatings Technology. 180-181: 71-75. ... Plastics, such as polyethylene naphthalate (PEN), can be protected by applying zinc oxide coating. The coating reduces the ...
"International Drug Price Indicator Guide. Retrieved 8 December 2016.. *^ Hamilton, Richart (2015). Tarascon Pocket ... Methoxy polyethylene glycol-epoetin beta. *Peginesatide. Iron supplements. *Ferrous ascorbate. *Ferrous aspartate ... Mannitol is on the World Anti-Doping Agency's banned drug list due to concerns that it may mask other drugs. ... Mannitol is used as a cutting agent in various drugs that are used intranasally (snorted), such as cocaine. A mixture of ...
... polyethylene (PE), or glycol-modified polyethylene terephthalate (PETg). Cyclic olefin resins are generally amorphous and are ... In the US, blister packs are mainly used for packing physician samples of drug products or for over-the-counter (OTC) products ... The PE (polyethylene) forms a soft intermediate layer between the rigid PVC and PVDC layers. Triplex specifications exists in ... A tamper-evident package, according to the regulations of the Food and Drug Administration (21 CFR § 211.132), "is one having ...
One of the more common methods of antifouling comes from growing polymer chains from a surface, often by poly(ethylene glycol) ... leading to increased drag of up to 60%. The drag increase has been seen to decrease speeds by up to 10%, which can require ... The N-substituted glycine is structurally similar to ethylene glycol and is hydrophilic, so easily dissolves in water. In ... Other mechanisms impacted by biofouling include microelectrochemical drug delivery devices, papermaking and pulp industry ...
Asidi amino, kamusi elezo huru
"Polymers derived from the amino acid l-tyrosine: polycarbonates, polyarylates and copolymers with poly(ethylene glycol)". ... "Advanced Drug Delivery Reviews 55 (4): 447-466. doi:10.1016/S0169-409X(03)00038-3 . PMID 12706045 . http://linkinghub.elsevier. ... Low, K. C.; Wheeler, A. P.; Koskan, L. P. (1996). Commercial poly(aspartic acid) and Its Uses, Advances in Chemistry Series 248 ...
Methoxy polyethylene glycol-epoetin beta (CERA/Mircera). *Peginesatide. *Pegol sihematide (EPO-018B) ... Kieseier BC (June 2011). "The mechanism of action of interferon-β in relapsing multiple sclerosis". CNS Drugs. 25 (6): 491-502 ... Hebenstreit D, Horejs-Hoeck J, Duschl A (May 2005). "JAK/STAT-dependent gene regulation by cytokines". Drug News & Perspectives ...
Methoxy polyethylene glycol-epoetin beta (CERA/Mircera). *Peginesatide. *Pegol sihematide (EPO-018B) ... The TRAIL gene as a drug target. TIC10 (which causes expression of TRAIL) was investigated in mice with various tumour ... The TRAIL receptors as a drug target. In clinical trials only a small proportion of cancer patients responded to various ... Cormier Z (February 2013). "Small-molecule drug drives cancer cells to suicide". Nature. 494. doi:10.1038/nature.2013.12385.. ...
WHO Model List of Essential Medicines
the square box applies to epoetin alfa, beta and theta, darbepoetin alfa, methoxy polyethylene glycol-epoetin beta,and their ... World Health Organization (1977). The selection of essential drugs : report of a WHO expert committee [meeting held in Geneva ... Rose, K; Anker, JNVd (2010). Guide to Paediatric Drug Development and Clinical Research. Karger Medical and Scientific ...
The lipid shell is also covered with a polyethylene glycol (PEG) layer. PEG prevents microbubble aggregation and makes the ... Drug Delivery: drugs can be incorporated into the microbubble's lipid shell. The microbubble's large size relative to other ... drug delivery vehicles like liposomes may allow a greater amount of drug to be delivered per vehicle. By targeted the drug- ... "Drugs in R&D, Volume 3, Number 5, 2002, pp. 306-309(4). Adis International. Retrieved 2010-03-08.. ...
Chemical burns from skin exposures can be decontaminated by washing with polyethylene glycol, isopropyl alcohol, or ... "drugs.com.. *^ "How Does Our Lip Balm Work". Carmex. Archived from the original on 18 February 2015. Retrieved 18 February 2015 ... and polyethylene glycol/industrial methylated spirits in the treatment of acute phenol burns". Annals of Emergency Medicine. 21 ... a comparison of the relative efficacy of water versus polyethylene glycol/industrial methylated spirits". Toxicol Appl ...
An experiment comparing the permeability of quantum dots coated in polyethylene glycol (PEG), PEG-amine, and carboxylic acid ... Drug Discovery. 3 (2): 115-124. doi:10.1038/nrd1304. PMID 15040576.. *^ Gao, X.; Cui, Y.; Levenson, R.; Chung, L.; Nie, S. ( ... Transdermal patches have been limited to administer a small number of drugs, such as nicotine, because of the limitations in ... Development of techniques that increase skin permeability has led to more drugs that can be applied via transdermal patches and ...
Granulocyte colony-stimulating factor
... but it has not been approved by the Food and Drug Administration for use in the United States. The drug has also been tested ... Polyethylene glycol (macrogol). *Sodium phosphate. *Sodium sulfate. *Sodium tartrate. *Sorbitol. Enemas. *Bisacodyl ... Prucalopride, brand name Resolor / DuphaPro among others, is a drug acting as a selective, high affinity 5-HT4 receptor agonist ... Frampton, J. E. (2009). "Prucalopride". Drugs. 69 (17): 2463-2476. doi:10.2165/11204000-000000000-00000. PMID 19911858.. ...
Liquid paraffin (drug)
Polyethylene glycol (macrogol). *Sodium phosphate. *Sodium sulfate. *Sodium tartrate. *Sorbitol. Enemas. *Bisacodyl ... This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.. *v ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Liquid_paraffin_(drug)&oldid=870518405" ...
pegylation: covalent attachment of polyethylene glycol (PEG) using a pegylation reagent, typically to the N-terminus or the ... a b Substance Abuse and Mental Health Services Administration, Results from the 2013 National Survey on Drug Use and Health: ... Ruffle JK (November 2014). "Molecular neurobiology of addiction: what's all the (Δ)FosB about?". Am J Drug Alcohol Abuse. 40 (6 ... The addictive phenotype can be lifelong, with drug craving and relapse occurring even after decades of abstinence. Post- ...
Silicon naphthalocyanine attached to copolymer PEG-PCL (poly(ethylene glycol)-block-poly(ε-caprolactone)) accumulates ... "Metal-Based Drugs. 2008: 276109. doi:10.1155/2008/276109. ISSN 0793-0291. PMC 2535827. PMID 18815617.. This article contains ... The drug targets the neovasculature that is caused by the condition. Photoimmunotherapy. Photoimmunotherapy is an ... Selbo, PK; A Hogset; L Prasmickaite; K Berg (2002). "Photochemical internalisation: a novel drug delivery system". Tumour Biol ...
"Microscopic Dynamics of Polyethylene Glycol Chains Interacting with Silica Nanoparticles". Physical Review Letters. 110 (17): ... a trigger for drug release. The presence of the model drug was established by fluorescence spectroscopy and the same holds for ... Such drug carrier particles possess additional choice of the axial ratio, the curvature, and the "all-sweeping" hydrodynamic- ... Nano tubes are also used for carrying drugs in general therapy and in tumor therapy in particular. The role of them is to ...
Methoxy polyethylene glycol-epoetin beta (CERA/Mircera). *Peginesatide. *Pegol sihematide (EPO-018B) ... Drug Interactions of Erythropoietin Alfa at Drugs.com *^ Hardell L, Walker MJ, Walhjalt B, Friedman LS, Richter ED (March 2007 ... In addition, on March 9, 2007, drug manufacturers agreed to new black box warnings about the safety of these drugs. ... Manufacturers were asked to suspend drug rebate programs for physicians and to also suspend marketing the drugs to patients. ...
In 1956 DuPont introduced polyether polyols, specifically poly(tetramethylene ether) glycol, and BASF and Dow Chemical started ... Regulatory information can be found in the Code of Federal Regulations Title 21 (Food and Drugs) and Title 40 (Protection of ... A special class of polyether polyols, poly(tetramethylene ether) glycols, which are made by polymerizing tetrahydrofuran, are ... distillation bottoms with glycols such as diethylene glycol. These low molecular weight, aromatic polyester polyols are used in ...
Esters of fatty acids with more complex alcohols, such as sorbitol, ethylene glycol, diethylene glycol, and polyethylene glycol ... "Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems". NeuroRx. 2 (1): 54-62. ... "Role of monocarboxylate transporters in drug delivery to the brain". Curr. Pharm. Des. 20 (10): 1487-98. doi:10.2174/ ...
Insuficiència renal crònica - Viquipèdia, l'enciclopèdia lliure
29] The U.S. Food and Drug Administration states that no "significant difference" has been found between milk from treated and ... The cow is considered [poly-estrous], which means that she will continue to undergo regular estrous cycles until death unless ... section of the PHE is added to remove the remaining heat with a mixture of chilled pure water and propylene glycol. These ... "U.S. Food and Drug Administration. 12 February 2003. Archived from the original on 21 February 2008. Retrieved 26 September ...
Type 1 (polyethylene terephthalate) is commonly found in soft drink and water bottles. Type 2 (high-density polyethylene) is ... The terephthalate diester can be used with ethylene glycol to form a new polyester polymer, thus making it possible to use the ... Type 4 (low-density polyethylene) is found in shopping bags, squeezable bottles, tote bags, clothing, furniture, and carpet. ... "Life Cycle Analysis of Distributed Recycling of Post-consumer High Density Polyethylene for 3-D Printing Filament". Journal of ...
Polyethylene Glycol 3350: MedlinePlus Drug Information
Polyethylene Glycol 3350: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Take polyethylene glycol 3350 exactly as directed.. Polyethylene glycol 3350 may be habit-forming. Do not take a larger dose, ... Before taking polyethylene glycol 3350,. *tell your doctor and pharmacist if you are allergic to polyethylene glycol or any ... Polyethylene glycol 3350 is used to treat occasional constipation. Polyethylene glycol 3350 is in a class of medications called ...
Polyethylene glycol-electrolyte solution (PEG-ES): MedlinePlus Drug Information
Polyethylene glycol-electrolyte solution (PEG-ES): learn about side effects, dosage, special precautions, and more on ... Polyethylene glycol-electrolyte solution (PEG-ES) comes as a powder to mix with water and take by mouth. Certain PEG-ES ... Polyethylene glycol-electrolyte solution (PEG-ES) is used to empty the colon (large intestine, bowel) before a colonoscopy ( ... Polyethylene glycol-electrolyte solution (PEG-ES). pronounced as (pol ee eth i leen) (glye col) ...
Polyethylene Glycol-Electrolyte Solution (MoviPrep, Plenvu) - Drugs.com
Easy-to-read patient leaflet for Polyethylene Glycol-Electrolyte Solution (MoviPrep, Plenvu). Includes indications, proper use ... Polyethylene Glycol-Electrolyte Solution (MoviPrep, Plenvu). Generic Name: Polyethylene Glycol-Electrolyte Solution (MoviPrep, ... Polyethylene glycol 3350 and electrolytes (Advanced Reading). *Polyethylene glycol 3350, electrolytes, and ascorbic acid ( ... More about polyethylene glycol 3350 with electrolytes. *Polyethylene glycol 3350 with electrolytes Side Effects ...
Polyethylene Glycol 3350 Dosage Guide with Precautions - Drugs.com
Detailed Polyethylene Glycol 3350 dosage information for adults. Includes dosages for Constipation and Bowel Preparation; plus ... Bowel Preparation MiraLax, senna, polyethylene glycol 3350, bisacodyl, Dulcolax, Senokot, erythromycin, neomycin, More... ... Constipation MiraLax, Colace, docusate, magnesium oxide, senna, polyethylene glycol 3350, bisacodyl, Metamucil, More... ... Constipation, Acute MiraLax, polyethylene glycol 3350, lactulose, docusate / senna, GlycoLax, Generlac, More... ...
Polyethylene Glycol 3350 With Electrolytes - Side Effects, Dosage, Interactions - Drugs - Everyday Health
Polyethylene glycol electrolyte solution is a laxative solution that increases the amount of water in the intestinal tract to ... Other drugs may interact with polyethylene glycol electrolyte solution, including prescription and over-the-counter medicines, ... You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition ... About Drugs A-Z. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members ...
Polymers | Free Full-Text | Transparent Low Molecular Weight Poly(Ethylene Glycol) Diacrylate-Based Hydrogels as Film Media for...
In this study, poly(ethylene glycol)-based hydrogels containing a model dye were synthesized by ultraviolet (UV-A) ... Hydrogels have shown a great potential as materials for drug delivery systems thanks to their usually excellent bio- ... poly(ethylene glycol) diacrylate; photodynamic therapy hydrogels; drug release; photopolymerization; photosensitizer; poly( ... Transparent Low Molecular Weight Poly(Ethylene Glycol) Diacrylate-Based Hydrogels as Film Media for Photoswitchable Drugs by ...
Amphiphilic drug persuaded collapse of polyvinylpyrrolidone and poly(ethylene glycol) chains: a dynamic light scattering study.
We have studied the interaction between an amphiphilic drug, amitriptyline hydrochloride (AMT), and neutral polymers, ... Polyethylene Glycols / chemistry*. Povidone / chemistry*. Scattering, Radiation*. Sodium Compounds / chemistry. Solutions. ... 0/Bromides; 0/Polyethylene Glycols; 0/Sodium Compounds; 0/Solutions; 50-48-6/Amitriptyline; 7647-15-6/sodium bromide; 9003-39-8 ... may be helpful to design the drug delivery systems for the antidepressant drugs as the higher concentration of these drugs is ...
An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene...
Life Brand Clearlax Laxative Powder for Oral Solution Contains Polyethylene Glycol 3350 119g | Shoppers Drug Mart®
Learn more about Life Brand Clearlax Laxative Powder for Oral Solution Contains Polyethylene Glycol 3350 119g in Antacids & ... Laxatives, Everyday Medicines & First Aid with Shoppers Drug Mart ... SHOPPERS DRUG MART EMAILS Join the Shoppers Drug Mart email ... Life Brand Clearlax Laxative Powder for Oral Solution Contains Polyethylene Glycol 3350 119g. ... Shoppers Drug Mart Inc. 243 Consumers Road, Toronto, Ontario M2J 4W8 www.shoppersdrugmart.ca ...
Balloon-Occluded Transcatheter Arterial Chemoembolization (b-TACE) for Hepatocellular Carcinoma Performed with Polyethylene...
Lucatelli P (2018) Polyethylene glycol (PEG)-epirubicin loaded drug-elunting embolic (DEE)-TACE procedures utilizing a combined ... The aim of this study is to describe our experience with b-TACE performed with polyethylene-glycol epirubicin-loaded drug- ... for Hepatocellular Carcinoma Performed with Polyethylene-Glycol Epirubicin-Loaded Drug-Eluting Embolics: Safety and Preliminary ... The embolization was then performed, according to our routine clinical practice, with drug-eluting microsphere (Lifepearl, ...
Polyethylene Glycol 3350 And Electrolytes (Oral Route) Description and Brand Names - Mayo Clinic
... www.mayoclinic.org/drugs-supplements/polyethylene-glycol-3350-and-electrolytes-oral-route/description/drg-20062627 ... The polyethylene glycol (PEG) and electrolytes solution is used to cleanse the colon (bowel) before certain medical tests (eg, ... Information about this polyethylene-glycol-3350-and-electrolytes-oral-route. Pregnancy Category. Explanation. ... Drug Interactions Although certain medicines should not be used together at all, in other cases two different medicines may be ...
Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma...
Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma ... Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma ... Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma ... Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma ...
DailyMed - PEG-3350, SODIUM CHLORIDE, SODIUM BICARBONATE AND POTASSIUM CHLORIDE- polyethylene glycol 3350, sodium chloride,...
View Label Archives for this drug. PEG-3350, SODIUM CHLORIDE, SODIUM BICARBONATE AND POTASSIUM CHLORIDE- polyethylene glycol ... polyethylene glycol 3350 (UNII: G2M7P15E5P) (polyethylene glycol 3350 - UNII:G2M7P15E5P) polyethylene glycol 3350. 420 g in 4 L ... Get Label RSS Feed for this Drug. PEG-3350, SODIUM CHLORIDE, SODIUM BICARBONATE AND POTASSIUM CHLORIDE- polyethylene glycol ... 7 DRUG INTERACTIONS 7.1 Drugs that May Lead to Fluid and Electrolyte Abnormalities 7.2 Potential for Altered Drug Absorption ...
Peg-3350, potassium chloride, sodium bicarbonate, sodium chloride / polyethylene glycol 3350; potassium chloride; sodium...
National Drug Code. Package Code. Package. PEG-3350, POTASSIUM CHLORIDE, SODIUM BICARBONATE, SODIUM CHLORIDE. polyethylene ... polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. FOR SOLUTION;ORAL. 090019. ANDA. Lupin ... The generic ingredient in PEG-3350, POTASSIUM CHLORIDE, SODIUM BICARBONATE, SODIUM CHLORIDE is polyethylene glycol 3350; ... Additional details are available on the polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride ...
Synthesis and drug release of star shape poly(benzyl L-aspartate)-b-poly(ethylene glycol) copolymers with POSS cores-何斌
Synthesis and drug release of star shape poly(benzyl L-aspartate)-b-poly(ethylene glycol) copolymers with POSS cores ... Firstly, the block copolymer poly(benzyl L-aspartate)-b-poly(ethylene glycol) (PBLA-b-PEG) was synthesized via ring-opening ... 关键字：star shape poly(benzyl L-aspartate)-b-poly(ethylene glycol) copolymers. 论文来源：期刊. 具体来源：Macromol. Biosci. 2014, 14(2): 289-97 ... Quercetin was used as a model drug and trapped in the micelles to study the potency of micelles as drug carriers. The drug ...
Synthesis and characterization of methoxy poly(ethylene glycol)-O-chitosan-polyethylenimine as a noviral carrier for gene...
... and methoxy poly (ethylene glycol) (mPEG) onto chitosan, the copolymer was characterized and confirmed by 1H-NMR and FT-IR ... ethylene glycol)-O-chitosan- polyethylenimine(mPEG-O-CS-PEI), was synthesized by grafting polycationic polyethylenimine (PEI) ... Drug & Gene Delivery Chapter 5. Synthesis and characterization of methoxy poly(ethylene glycol)-O-chitosan-polyethylenimine as ... A novel water-soluble chitosan (CS) derivative３methoxy poly(ethylene glycol)-O-chitosan- polyethylenimine(mPEG-O-CS-PEI), was ...
Mircera (Epoetin Beta And Methoxy Polyethylene Glycol) - Side Effects, Interactions, Uses, Dosage, Warnings | Everyday Health
Learn more about Mircera (Epoetin Beta And Methoxy Polyethylene Glycol) at EverydayHealth.com. ... Epoetin Beta And Methoxy Polyethylene Glycol), including what it is used for, warnings, reviews, side effects, and interactions ... Find Another Drug. Search prescription drugs, over-the counter medications, and supplements. CLEAR. ... This medicine is not for treating anemia caused by cancer chemotherapy. Epoetin beta and methoxy polyethylene glycol may ...
MoviPrep, PlenVu (polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid) dosing, indications, interactions, adverse...
... polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid), frequency-based adverse effects, comprehensive interactions, ... Drugs & Diseases. polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid (Rx). Brand and Other Names:MoviPrep, Plenvu ... polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid (Rx). *. Sections polyethylene glycol/electrolytes/sodium ... polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid (MoviPrep%2C PlenVu)) and polyethylene glycol/electrolytes/ ...
Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against...
Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against ... Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against ... Methods: Poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG) self-sintering paste was loaded with the ... Glioblastoma, Drug Delivery Systems, Neurosurgery. Schools/Departments:. University of Nottingham, UK , Faculty of Medicine and ...
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) - Full Text View - ClinicalTrials.gov
Drug: Polyethylene Glycol 3350 If subject is randomized to this group, one time dose of one gallon polyethylene glycol 3350 ... Drug Information available for: Lactulose Polyethylene glycol 400 Polyethylene Macrogol Genetic and Rare Diseases Information ... Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) (HELP). The safety and scientific validity of this study is ... The purpose of this study is to evaluate whether the use of polyethylene glycol is superior and more safe in treating hepatic ...
Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic...
Active Comparator: Polyethylene glycol 3350-electrolyte solution (GoLYTELY®) Drug: Polyethylene glycol 3350-electrolyte ... Drug Information available for: Lactulose Polyethylene Macrogol GoLytely Electrolytes Genetic and Rare Diseases Information ... Polyethylene glycol for hepatic encephalopathy: a new solution to purge an old problem? JAMA Intern Med. 2014 Nov;174(11):1734- ... This study is being done to find out if the laxative polyethylene glycol (also known as GoLYTELY® or Miralax®) can treat your ...
Nanomaterials | Free Full-Text | Gold Rod-Polyethylene Glycol-Carbon Dot Nanohybrids as Phototheranostic Probes | HTML
... nanosized luminescent material using the incorporation of red emissive carbon dots on gold nanorods through polyethylene glycol ... Drug Deliv. Rev. 2013, 65, 1951-1963. [Google Scholar] [CrossRef] [PubMed]. *Sun, M.; Xu, L.; Ma, W.; Wu, X.; Kuang, H.; Wang, ... Polyethylene glycol (PEG) is a biocompatible polymer that has been used for an extremely wide range of products, ranging from ... Beijing, China). Thiolated and methoxyl terminated polyethylene glycol (mPEG-SH, molecular weight 1000 Da), Thiolated and ...
Polyethylene Glycol 3350, Sodium And Potassium Salts (Oral Route) Description and Brand Names - Mayo Clinic
Methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa for anemia in non-dialysis-dependent CKD: a systematic review ...
Drugs. 2008;68:1139-56.PubMedCrossRefGoogle Scholar. *. 33.. Macdougall IC. New anemia therapies: translating novel strategies ... Methoxy polyethylene glycol-epoetin beta: worth waiting for or a novelty worn off? Expert Opin Pharmacother. 2009;10:1509-14. ... Methoxy polyethylene glycol-epoetin beta: a review of its use in the management of anaemia associated with chronic kidney ... Anemia CERA Chronic kidney disease EPO Erythropoiesis stimulating agent Methoxy polyethylene glycol-epoetin beta Pre-dialysis ...
Frontiers | Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential...
This work discusses modifications including chitosan with attached cyclodextrin and poly(ethylene glycol), and the main ... This work discusses modifications including chitosan with attached cyclodextrin and poly(ethylene glycol), and the main ... Among the chitosan derivatives, cyclodextrin-grafted chitosan and poly(ethylene glycol)-grafted chitosan are excellent ... ethylene glycol)-grafted chitosan are excellent candidates for a range of biomedical, environmental decontamination, and ...
Efficacy of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) Compared to Interferon Alfa-2B in Participants With...
Have history of substance abuse, such as alcohol, intravenous drugs and inhaled drugs. ... Efficacy of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) Compared to Interferon Alfa-2B in Participants With ... Efficacy of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) Compared to Interferon Alfa-2B in Participants With ... Comparison of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) vs. Interferon Alfa-2B for Treatment of Adult ...
Patent WO2012162019A1 - Thiobis phenolic antioxidant/polyethylene glycol blends - Google Patents
... crosslinkable polyethylene by first forming a blend, preferably a dry blend, of the antioxidant with a polyalkylene glycol (PAG ... The incorporation of thiobis phenolic antioxidant and PAG blend into polyethylene provides the PE with high oxidative induction ... and then mixing the blend with the polyethylene. ... Molded drag reduction coatings. US4101445. 22 Sep 1976. 18 Jul ... Though the polyethylene glycol is preferred, other polyalkylene glycols or mixtures of polyalkylene glycols may be used instead ...
Polyethylene Glycol/electrolyte (Colyte, GoLYTELY) | Davis's Drug Guide
... in Daviss Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, ... Find information on Polyethylene Glycol/electrolyte (Colyte, GoLYTELY) ... "Polyethylene Glycol/electrolyte." Daviss Drug Guide, 16th ed., F.A. Davis Company, 2019. Daviss Drug Guide - OLD - USE 2.0, ... polyethylene glycol/electrolyte is a topic covered in the Daviss Drug Guide. To view the entire topic, please sign in or ...
November 2017 - When do the patents on POLYETHYLENE GLYCOL 3350; POTASSIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE;...
SUNMARK CLEARLAX (polyethylene glycol 3350 powder, for solution) | Healthgrades.com
Starting polyethylene glycol-electrolyte solutionTaking polyethylene glycMirceraHydrophilicGolytelyInteract with polyethylene glycol-electrolyte solution2019PolymersMiraLaxNanoparticlesElectrolyteDevelopment of Polyethylene GlycolConstipationDosageMethoxy polyethylene glycolElectrolytes for Oral SolutionPolymerHydrogelsBowel3350 comesLaxativesPEGsDavis's Drug GuideLactic acidPropylene GlycolLaxative solutionTake polyethylenePreparationSodium bicarbonateEncapsulationChitosanDavis-Drug-GuideEfficacy of a novelMacrogolInteractionsLactuloseClinicalErythropoiesis-stimulCopolymerTumorEtherEthylene oxideMedicationPolyalkylenePhenolicCyclodextrinPhospholipid
Starting polyethylene glycol-electrolyte solution1
Taking polyethylene glyc2
- On June 7, 2018, the Food and Drug Administration approved methoxy polyethylene glycol-epoetin beta (Mircera, Vifor Pharma Inc.) for the treatment of pediatric patients 5 to 17 years of age on hemodialysis who are converting from another ESA after. (medworm.com)
- Mircera (methoxy polyethylene glycol-epoetin beta) is an erythropoiesis-stimulating agent (ESA). (centerwatch.com)
- Mircera belongs to a group of drugs called erythropoiesis-stimulating agent (ESA). (rxwiki.com)
- Using an in vitro guinea pig spinal cord injury model, we have shown that polyethylene glycol (PEG), a hydrophilic polymer, can significantly accelerate and enhance the membrane resealing process to restore membrane integrity following controlled compression. (nih.gov)
- Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. (sigmaaldrich.com)
- 6-8 Among these materials poly(ethylene glycol) (PEG) is a widely used and thoroughly studied hydrophilic protein repelling polymer. (rsc.org)
- The development of liposomes coated with the hydrophilic polymer polyethylene glycol (PEG) greatly broadened the application of liposomes ( Woodle and Lasic, 1992 ). (aspetjournals.org)
- The nanoparticle's "corona" can be functionalized with hydrophilic polymers, targeting molecules, therapeutic Drugs, and image contrast agents. (scirp.org)
- Studies on animal model have suggested that polyethylene glycol 3350-electrolyte solution (GOLYTELY) is effective in clearing gut bacteria and reducing the ammoniagenesis in colon. (clinicaltrials.gov)
- Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. (clinicaltrials.gov)
- This study is being done to find out if the laxative polyethylene glycol (also known as GoLYTELY® or Miralax®) can treat your hepatic encephalopathy (confusion due to your liver disease and/or cirrhosis) better and/or more safely than lactulose (another laxative). (clinicaltrials.gov)
- In this study, the investigators will evaluate if polyethylene glycol (GoLYTELY®) is more effective than lactulose on neurocognition (memory and thinking skills) and determine if it decreases the hospital stay. (clinicaltrials.gov)
- Polyethylene glycol electrolyte solution ( colyte ® , GoLYTELY ® , MoviPrep ® , NuLYTELY ® , TriLyte ® ) is a prescription medication licensed to empty the bowel before certain intestinal procedures, including a colonoscopy or a barium enema x-ray examination. (emedtv.com)
Interact with polyethylene glycol-electrolyte solution2
- This is not a list of all drugs or health problems that interact with polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Other drugs may interact with polyethylene glycol electrolyte solution, including prescription and over-the-counter medicines, vitamins, and herbal products. (everydayhealth.com)
- We have studied the interaction between an amphiphilic drug, amitriptyline hydrochloride (AMT), and neutral polymers, polyvinylpyrrolidone (PVP) and poly(ethylene glycol) (PEG), using the dynamic light scattering (DLS) technique. (biomedsearch.com)
- Sterically stabilized liposome is characterized by a surface coating of polyethylene glycol (PEG) or other polymers that can reduce opsonization of the liposome by plasma proteins. (aacrjournals.org)
- Herein, a simple centrifugal spinning without the drawbacks of electrospinning was applied to fabricate polyethylene glycol-based PCM fibres with nano-SiC as a highly conductive filler, polyacrylonitrile as the supporting material, and N,N-dimethylformamide as the solvent to dissolve the polymers. (medworm.com)
- Polyethylene glycol (PEG) and related polymers (PEG phospholipid constructs) are often sonicated when used in biomedical applications. (wikipedia.org)
- New York, NY -- ( SBWIRE ) -- 12/08/2016 -- Polyethylene glycol (PEG) is one of the most frequently used non-ionic polymers in polymer-based drug delivery and other bioactivities. (sbwire.com)
- The existent scientific literature testifies for the various applications of polymers derived from polyethylene glycol (PEGs). (sbwire.com)
- Polyethylene glycol (PEG) is a family of long chain polymers attached to a glycerine backbone. (novusbio.com)
- Taking miralax (polyethylene glycol) cause low potassium? (healthtap.com)
- Is it safe to take vitamin C supplements of 250mg with Propranolol, Levothyroxine and Miralax (polyethylene glycol)? (healthtap.com)
- Miralax ( polyethylene glycol ) dosed at 17 gm/day( a heaping tablespoon in 4-8 ounces of fluid) max 34gm/day. (healthtap.com)
- Antibacterial activity of silver nanoparticles coated with different functionalizing agents i.e., polyethylene glycol, tween 80 and sodium dodecyl sulphate were evaluated on both normal and multi-drug resistant strains of bacteria. (ingentaconnect.com)
- Among these, poly- ethylene glycol coated nanoparticles were most effective in killing all the bacterial strains which includes Escherichia coli DH5 α , Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus and multi-drug resistant clinical isolates of Shigella spp . (ingentaconnect.com)
- The minimum inhibitory concentration of polyethylene glycol coated silver nanoparticles was also less compared to the other two sets of nanoparticles. (ingentaconnect.com)
- Consistence with that polyethylene glycol coated nanoparticles produced more intracellular reactive oxygen species in bacteria. (ingentaconnect.com)
- Thus our present investigation implicates the potential therapeutic use of silver nanoparticles as antibacterial agent particularly the polyethylene glycol coated one. (ingentaconnect.com)
- Long-circulating poly(ethylene glycol)-grafted gelatin nanoparticles customized for intracellular delivery of noscapine: preparation, in-vitro char. (nih.gov)
- Noscapine-enveloped gelatin nanoparticles and poly(ethylene glycol)-grafted gelatin nanoparticles were constructed and characterized. (nih.gov)
- It is to be noted that there is a 1.43-fold increase in the area under the curve up to the last sampling point for the noscapine-loaded poly(ethylene glycol)-grafted gelatin nanoparticles over the noscapine-loaded gelatin nanoparticles and a 13.09-fold increase over noscapine. (nih.gov)
- In this study, we developed poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles with variable molecular PEG weights (2, 10, or 20 kDa) to encapsulate antifungal amphotericin B (AmB) and to evaluate its in vitro efficacy in strains of Candida sp. (eurekaselect.com)
- Caroline Danziato Rodrigues, Diani Meza Casa, Luciana Facco Dalmolin, Luciana Erzinger Alves de Camargo, Najeh Maissar Khalil and Rubiana Mara Mainardes, "Amphotericin B-Loaded Poly(Lactide)-Poly(Ethylene Glycol)-Blend Nanoparticles: Characterization and In Vitro Efficacy and Toxicity", Current Nanoscience (2013) 9: 594. (eurekaselect.com)
- Abstract 4505: Preparation and anti-tumor growth of polyethylene glycol-poly lactic acid block copolymers sorafenib nanoparticles. (aacrjournals.org)
- Polyethylene glycol-poly lactic acid block copolymers sorafenib nanoparticles were prepared with nanometer precipitation method. (aacrjournals.org)
- Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. (nih.gov)
- Iron oxide nanoparticles have found widespread applications in different areas including cell separation, drug delivery and as contrast agents. (nih.gov)
- Due to water insolubility and stability issues, nanoparticles utilized for biological applications require coatings such as the commonly employed polyethylene glycol (PEG). (nih.gov)
- The anticancer drug doxorubicin (DOX) was encapsulated in the nanoparticles during preparation. (elsevier.com)
- Drug loading amounts and release behavior from prepared nanoparticles were investigated. (elsevier.com)
- The cell cytotoxicity of prepared nanoparticles was evaluated for receptor mediated drug delivery. (elsevier.com)
- Today nanoparticles based drug delivery or imaging agents are extremely being investigated as a very powerful tool in early diagnostics or treatment of different kinds of cancers including prostate malignancies. (scirp.org)
- Stereocomplexed poly(lactic acid)-poly(ethylene glycol) nanoparticles with dual-emissive boron dyes for tumor accumulation. (duke.edu)
- Polyethylene glycol-electrolyte solution (PEG-ES) is used to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) or barium enema (a test in which the colon is filled with a fluid and then x-rays are taken) so that the doctor will have a clear view of the walls of the colon. (medlineplus.gov)
- Polyethylene glycol-electrolyte solution (PEG-ES) comes as a powder to mix with water and take by mouth. (medlineplus.gov)
- What do I need to tell my doctor BEFORE I take Polyethylene Glycol-Electrolyte Solution? (drugs.com)
- If you have an allergy to polyethylene glycol or any other part of polyethylene glycol-electrolyte solution ( moviPrep , plenvu). (drugs.com)
- You must check to make sure that it is safe for you to take polyethylene glycol-electrolyte solution (moviPrep, plenvu) with all of your drugs and health problems. (drugs.com)
- What are some things I need to know or do while I take Polyethylene Glycol-Electrolyte Solution? (drugs.com)
- Tell all of your health care providers that you take polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- If you are over the age of 60, use polyethylene glycol-electrolyte solution (moviPrep, plenvu) with care. (drugs.com)
- You will need to talk about the benefits and risks of using polyethylene glycol-electrolyte solution (moviPrep, plenvu) while you are pregnant. (drugs.com)
- How is this medicine (Polyethylene Glycol-Electrolyte Solution) best taken? (drugs.com)
- Use polyethylene glycol-electrolyte solution (moviPrep, plenvu) as ordered by your doctor. (drugs.com)
- Take polyethylene glycol-electrolyte solution (moviPrep, plenvu) as your doctor has told you. (drugs.com)
- This includes when to take polyethylene glycol-electrolyte solution (moviPrep, plenvu), foods and drinks to avoid before the exam, and when to stop eating and drinking before the exam. (drugs.com)
- Talk with your doctor about how to take your other drugs with polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Mix with water as told before you take polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Drink clear liquids before, during, and after taking polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Do not eat solid food while taking polyethylene glycol-electrolyte solution (moviPrep, plenvu). (drugs.com)
- Call your doctor if you are not able to finish polyethylene glycol-electrolyte solution (moviPrep, plenvu) before your exam. (drugs.com)
- Polyethylene glycol electrolyte solution is a laxative solution that increases the amount of water in the intestinal tract to stimulate bowel movements. (everydayhealth.com)
- Polyethylene glycol electrolyte solution is used to clean the bowel before colonoscopy, a barium x-ray, or other intestinal procedures. (everydayhealth.com)
- Polyethylene glycol electrolyte solution may also be used for purposes not listed in this medication guide. (everydayhealth.com)
- Polyethylene glycol electrolyte solution can cause dangerous or life-threatening side effects in people with these conditions. (everydayhealth.com)
- FDA pregnancy category C. It is not known whether polyethylene glycol electrolyte solution will harm an unborn baby. (everydayhealth.com)
- It is not known whether polyethylene glycol electrolyte solution passes into breast milk or if it could harm a nursing baby. (everydayhealth.com)
- Avoid taking other medications, vitamins, or mineral supplements within 1 hour before drinking polyethylene glycol electrolyte solution. (everydayhealth.com)
- Do not use other laxatives while using polyethylene glycol electrolyte solution unless your doctor has told you to. (everydayhealth.com)
- Polyethylene glycol electrolyte solution is a powder medicine that must be mixed with water before using it. (everydayhealth.com)
- polyethylene glycol/electrolyte is a topic covered in the Davis's Drug Guide . (drugguide.com)
- Davis's Drug Guide - OLD - USE 2.0 , www.drugguide.com/ddo/view/Davis-Drug-Guide/51622/all/polyethylene_glycol_electrolyte. (drugguide.com)
- What is the most important information I should know about polyethylene glycol electrolyte solution? (healthbanks.com)
- What should I discuss with my health care provider before taking polyethylene glycol electrolyte solution? (healthbanks.com)
- How should I take polyethylene glycol electrolyte solution? (healthbanks.com)
- The first watery stool should appear within 1 hour after you start drinking polyethylene glycol electrolyte solution. (healthbanks.com)
- Polyethylene glycol electrolyte solution will produce watery diarrhea. (healthbanks.com)
- In most cases, at least 3 liters of polyethylene glycol electrolyte solution is needed for the full effect. (healthbanks.com)
- Throw away any polyethylene glycol electrolyte solution you have not used within 24 to 48 hours after it was mixed (follow directions for your specific brand of this medicine). (healthbanks.com)
- No research has been done to determine if polyethylene glycol electrolyte solution would pass through human breast milk. (emedtv.com)
- However, it's still important to consult your healthcare provider if you are thinking of breastfeeding while using polyethylene glycol electrolyte solution. (emedtv.com)
- Can Women Take Polyethylene Glycol Electrolyte Solution While Breastfeeding? (emedtv.com)
- Therefore, if you are nursing a child, talk with your healthcare provider before taking polyethylene glycol electrolyte solution. (emedtv.com)
- However, because polyethylene glycol electrolyte solution has not been studied in women who are breastfeeding, every potential problem cannot yet be ruled out. (emedtv.com)
- Polyethylene glycol (PEG) 3350 solution without added electrolytes is an odourless osmotic laxative, which, unlike other colonic lavage solutions, carries no risk of salt absorption and hence no risk of electrolyte imbalance. (cfp.ca)
Development of Polyethylene Glycol1
- Some of the new experiments being done in the field of research & development such as the development of polyethylene glycol hydrogels which are used as adhesives for wound healing, wound closure, regenerative medicine tool with dopamine, tissue models and cell cultures will lead to opportunities for the polyethylene glycol market. (sbwire.com)
- Polyethylene glycol 3350 is used to treat occasional constipation. (medlineplus.gov)
- Polyethylene glycol 3350 is an osmotic laxative used for the treatment of occasional constipation in adults. (patientslikeme.com)
- Polyethylene glycol 3350 is a laxative solution, a completely different way to treat constipation. (mymedsbuy.com)
- Polyethylene glycol 3350 is used as a laxative to treat occasional constipation or irregular bowel movements. (mymedsbuy.com)
- Is polyethylene glycol safe and effective for chronic constipation in children? (bmj.com)
Methoxy polyethylene glycol17
- Epoetin beta and methoxy polyethylene glycol is a combination medicine used to treat anemia (lack of red blood cells) and to reduce the need for blood cell transfusions. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol is used to treat anemia caused by chronic kidney disease in adults, or in children at least 5 years old who are on hemodialysis. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol may increase tumor growth or decrease survival time in people with certain types of cancer. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol should not be used to take the place of an emergency blood cell transfusion. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol may also be used for purposes not listed in this medication guide. (everydayhealth.com)
- Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using epoetin beta and methoxy polyethylene glycol. (everydayhealth.com)
- Epoetin beta and methoxy polyethylene glycol is injected under the skin or given as an infusion into a vein. (everydayhealth.com)
- Different reviews have focused on evaluating the safety and efficacy of methoxy polyethylene glycol-epoetin beta (MPG-EPO), a continuous erythropoietin receptor activator, in CKD patients regardless of dialysis dependency and others have studied this novel agent exclusively in CKD patients receiving dialysis. (springer.com)
- Information about drug Epoetin Beta-Methoxy Polyethylene Glycol includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. (medindia.net)
- The generic Epoetin Beta-Methoxy Polyethylene Glycol is manufactured by one company. (medindia.net)
- Medindia's drug directory has currently 55 Brands of Epoetin Beta-Methoxy Polyethylene Glycol listed . (medindia.net)
- Epoetin beta-methoxy polyethylene glycol(Epogen) generic is an erythropoiesis-stimulating agent, prescribed for anemia in people with chronic kidney failure. (medindia.net)
- Emergency Central , emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/109352/all/methoxy_polyethylene_glycol_epoetin_beta. (unboundmedicine.com)
- In this work we study the influence of PEG concentration in mixed 1,2-dimyristoyl- sn-glycero -3-phosphoethanolamine (DMPE) and 1,2-dimyristoyl- sn-glycero -3-phosphoethanol-amine- N -[methoxy(polyethylene glycol)-(DMPE-PEG2000) phospholipid monolayers on both the amount and the orientational ordering extent of the adsorbed proteins. (rsc.org)
- This study assessed the long-term efficacy, safety, and tolerability of intravenous (iv) or subcutaneous (sc) methoxy polyethylene glycol-epoetin beta in chronic kidney disease patients with renal anemia. (druglib.com)
- Eligible patients were those who were receiving stable maintenance therapy with methoxy polyethylene glycol-epoetin beta or erythropoiesis stimulating agents (ESAs) in Phase II or III clinical studies. (druglib.com)
- They continued to receive methoxy polyethylene glycol-epoetin beta or comparator ESAs at the same weekly dose and by the same route of administration (sc or iv) as in the qualifying studies. (druglib.com)
Electrolytes for Oral Solution1
- 11. The method of claim 1 , wherein the polymer backbone is selected from the group consisting of linear or branched poly(alkylene oxide), linear or branched poly(vinyl pyrrolidone), linear or branched poly(vinyl alcohol), linear or branched polyoxazoline, and linear or branched poly(acryloylmorpholine). (google.com)
- PLGA or poly (lactic-co-glycolic acid) could be a polymer that is employed during a host of Food and Drug Administration (FDA) approved therapeutic devices, thanks to its biodegradability and biocompatibility. (scirp.org)
- Hydrogels have shown a great potential as materials for drug delivery systems thanks to their usually excellent bio-compatibility and their ability to trap water-soluble organic molecules in a porous network. (mdpi.com)
- In this study, poly(ethylene glycol)-based hydrogels containing a model dye were synthesized by ultraviolet (UV-A) photopolymerization of low-molecular weight macro-monomers and the material properties (dye release ability, transparency, morphology, and polymerization kinetics) were studied. (mdpi.com)
- In recent years, macroporous hydrogels are sought after for a wide range of tissue engineering and drug delivery applications. (aiche.org)
- In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. (ac.rs)
- The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. (ac.rs)
- ydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. (ac.rs)
- Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems. (ac.rs)
- This study presents a new strategy of tuning the encapsulation efficiency and the release rate of protein drugs from a PLGA microsphere by filling the hollow core of the microsphere with poly(ethylene glycol) (PEG) hydrogels of varying cross-linking density. (illinois.edu)
- It may take 2 to 4 days for polyethylene glycol 3350 to produce a bowel movement. (medlineplus.gov)
- The polyethylene glycol (PEG) and electrolytes solution is used to cleanse the colon (bowel) before certain medical tests (eg, colonoscopy, barium enema X-ray exam) or colon surgery. (mayoclinic.org)
- The polyethylene glycol (PEG), sodium and potassium salts solution is used to cleanse the colon (bowel) before a medical test (eg, colonoscopy). (mayoclinic.org)
- Background - Polyethylene glycol-based bowel preparations (PEGBPs) are widely perceived as safe and effective alternatives to oral sodium phosphate for bowel cleansing prior to colonoscopy. (ices.on.ca)
- Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. (healthtap.com)
- You should not use polyethylene glycol 3350 if you have a bowel obstruction or intestinal blockage. (mymedsbuy.com)
- You should not use this medicine if you are allergic to polyethylene glycol, or if you have a bowel obstruction or intestinal blockage. (mymedsbuy.com)
- Polyethylene glycol 3350 should produce a bowel movement within 1 to 3 days of using the medication. (mymedsbuy.com)
- Polyethylene glycol 3350 is in a class of medications called osmotic laxatives. (medlineplus.gov)
- Increased manufacturing of eye drops and laxatives coupled with the growth of pharmaceutical industry has increased the use of polyethylene glycol as a solvent which will drive the growth for polyethylene glycol market in future. (sbwire.com)
- Solid dispersions of 10% w/w griseofulvin in different polyethylene glycols (PEGs) with or without incorporation of alkali dodecyl sulphates (MDS) were prepared by the melting method. (diva-portal.org)
- PEGs and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. (wikipedia.org)
Davis's Drug Guide3
- Davis's Drug Guide for Nurses App + Web from F.A. Davis and Unbound Medicine covers 5000+ trade name and generic drugs. (drugguide.com)
- In Davis's Drug Guide (16th edition). (drugguide.com)
- Hi my name is I am interested in setting up a Davis's Drug Guide site license for my institution. (drugguide.com)
- We describe the preparation of organic semiconducting nanofibers comprising a crystalline poly(di-n-hexylfluorene) core and a solvated, segmented corona consisting of polyethylene glycol in the center and polythiophene at the ends. (medworm.com)
- The use of levo-ornidazole in the preparation of anti-parasitic infection drug is provided. (freepatentsonline.com)
- It is demonstrated that levo-ornidazole is superior to dextro-ornidazole and racemic ornidazole in the therapeutic action against parasitization (especially trichomonas vaginalis infection and cecal amoeba infection), and thus it is more practicable to formulate L-ornidazole as anti-parasitic infection drugs, and particularly as drug preparations which are suitable for clinical uses, including oral preparation, intravenous preparation and vaginal preparation. (freepatentsonline.com)
- The drug loading content and encapsulation efficiency increased with increasing the chain length of PBLA blocks. (polymer.cn)
- However, their use is often plagued by limited controllability of encapsulation efficiency, initial burst, and release rate of drug molecules, which cause unsatisfactory outcomes and several side effects including inflammation. (illinois.edu)
- The resulting PEG-PLGA core-shell microspheres exhibited (1) increased encapsulation efficiency, (2) decreased initial burst, and (3) a more sustained release of protein drugs, as the cross-linking density of the PEG gel core was increased. (illinois.edu)
- A novel water-soluble chitosan (CS) derivative３methoxy poly(ethylene glycol)-O-chitosan- polyethylenimine(mPEG-O-CS-PEI), was synthesized by grafting polycationic polyethylenimine (PEI) and methoxy poly (ethylene glycol) (mPEG) onto chitosan, the copolymer was characterized and confirmed by 1H-NMR and FT-IR spectra. (nsti.org)
- Among the chitosan derivatives, cyclodextrin-grafted chitosan and poly(ethylene glycol)-grafted chitosan are excellent candidates for a range of biomedical, environmental decontamination, and industrial purposes. (frontiersin.org)
- This work discusses modifications including chitosan with attached cyclodextrin and poly(ethylene glycol), and the main applications of these chitosan derivatives in the biomedical field. (frontiersin.org)
- Among the diverse developing nanomaterials, biocompatible biodegradable dendrimers and chitosan or PLGA (Poly Lactic-co-Glycolic Acid) derivatives are more considered due to their safer profiles. (scirp.org)
Efficacy of a novel2
- This paper investigates in vivo efficacy of a novel drug eluting paste in glioblastoma. (nottingham.ac.uk)
- The authors prospectively evaluated the safety and efficacy of a novel polyethylene glycol (PEG) hydrogel sealant in patients undergoing elective cranial surgery with documented cerebrospinal fluid (CSF) leakage after sutured dural repair. (thejns.org)
- The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (drugs.com)
- However, the presence of large molecules such as PEG on the liposomal surface may reduce the interactions of liposomes with cells and hinder entry of liposomes into the tumor tissue (11 , 12) , thereby possibly reducing the accumulation of liposomal drugs in the tumor tissue. (aacrjournals.org)
- Once again, would suggest that your pharmacist should have a computerized program that lists all drug interactions and therefore should be able to help you out. (healthtap.com)
- No drug interactions have been studied by the manufacturer. (rxwiki.com)
- Not all drug interactions are known or reported and new drug interactions are continually being reported. (rxwiki.com)
- Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P. (clinicaltrials.gov)
- The purpose of this study is to evaluate whether the use of polyethylene glycol is superior and more safe in treating hepatic encephalopathy compared to lactulose and also to determine if treatment with polyethylene glycol will reduce the duration of hospital stay. (clinicaltrials.gov)
- Recently published study by Robert Rahimi, University of Texas Southwestern Medical Center found that polyethylene glycol is more effective in improving HE over the first 24 hours compared to lactulose and also may reduce duration of hospital stay. (clinicaltrials.gov)
- Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns. (semanticscholar.org)
- These regimens, though effective, do not completely eliminate HIV and the development of drug resistance is a major clinical problem. (clinicaltrials.gov)
- As you have not prescribed this drug earlier, you want to appraise the evidence before using it in your clinical practice. (bmj.com)
- Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. (cancer.gov)
- Drug information typically includes the drug name, approval status, indication of use, and clinical trial results. (centerwatch.com)
- Firstly, the block copolymer poly(benzyl L-aspartate)- b -poly(ethylene glycol) (PBLA- b -PEG) was synthesized via ring-opening polymerization of β-benzyl L-aspartate-N-carboxyanhydride (BLA-NCA) with α-Methoxy-ω-aminopoly(ethylene glycol) (mPEG-NH 2 ) as a macroinitiator. (polymer.cn)
- The NPs were created by means of stereocomplexation using a methoxy-terminated polyethylene glycol and poly(D-lactide) (mPEG-PDLA) block copolymer combined with iodide-substituted difluoroboron dibenzoylmethane-poly(L-lactide) (BF2dbm(I)PLLA). (duke.edu)
- At a dose of 10 mg/kg, although both liposomal groups were better than the free drug group in terms of clinically relevant parameters, including toxicity, tumor shrinkage, and survival, there was no difference between the two liposomal drug groups. (aacrjournals.org)
- Dr. Dewhirst has research interests in tumor hypoxia, angiogenesis, hyperthermia and drug transport. (duke.edu)
- Polyethylene glycol 450 lauryl ether and breastfeeding. (e-lactancia.org)
- We do not have alternatives for Polyethylene glycol 450 lauryl ether . (e-lactancia.org)
- Different forms of PEG are also available, depending on the initiator used for the polymerization process - the most common initiator is a monofunctional methyl ether PEG, or methoxypoly(ethylene glycol), abbreviated mPEG. (wikipedia.org)
- Thiobis phenolic antioxidants are efficiently dry or melt blended with a tree-resistant, crosslinkable polyethylene by first forming a blend, preferably a dry blend, of the antioxidant with a polyalkylene glycol (PAG), and then mixing the blend with the polyethylene. (google.ca)
- 1. An additive mixture comprising at least one thiobis phenolic antioxidant and at least one polyalkylene glycol (PAG) of a weight average molecular weight of at least 1,000. (google.ca)
- 15. A method of mixing a solid thiobis phenolic antioxidant with polyethylene, the method comprising the steps of (A) mixing the thiobis phenolic antioxidant with polyalkylene glycol (PAG) to form a blend, and (B) mixing the blend with polyethylene. (google.ca)
- The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. (google.com)
- 2. The method of claim 1, wherein said polyalkylene oxide is polyethylene glycol. (google.com)
- The incorporation of thiobis phenolic antioxidant and PAG blend into polyethylene provides the PE with high oxidative induction time (OIT) which is a measure of the oxidative stability of the PE. (google.ca)
- 16. The method of Claim 15 in which the thiobis phenolic antioxidant and PAG are first dissolved in a common solvent to form the blend, and then the solvent is removed prior to mixing the blend with polyethylene. (google.ca)
- 17. The method of Claim 15 in which the thiobis phenolic antioxidant and PAG are melt-mixed to form the blend prior to mixing the blend with polyethylene. (google.ca)
- Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin. (sigmaaldrich.com)
- Thus the aqueous solubility of trans-resveratrol was investigated in the presence of growing concentrations of polyethylene glycol (PEG) or β-cyclodextrin (βCD) as solubilizing excipients. (sigmaaldrich.com)
- Could a liposomal drug composed of phospholipid with a higher transition temperature, such as DSPC (14 , 15 , 16) , even without PEG coating have antitumor activity equivalent to or better than a sterically stabilized one? (aacrjournals.org)
- We report here the influence of the poly(ethylene glycol) (PEG) grafting density in model phospholipid monolayers on the adsorption behavior of bovine serum albumin and human fibrinogen, not only with respect to the amount of adsorbed protein, but also its orientational ordering on the surface. (rsc.org)