A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984)
A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.
Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.
A species of fruit fly much used in genetics because of the large size of its chromosomes.
The relationship between two different species of organisms that are interdependent; each gains benefits from the other or a relationship between different species where both of the organisms in question benefit from the presence of the other.
Infections with bacteria of the family RICKETTSIACEAE.
A family of small, gram-negative organisms, often parasitic in humans and other animals, causing diseases that may be transmitted by invertebrate vectors.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
Proteins found in any species of insect.
ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.
Any of numerous winged hymenopterous insects of social as well as solitary habits and having formidable stings.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.
The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.
A genus of mosquitoes (CULICIDAE) frequently found in tropical and subtropical regions. YELLOW FEVER and DENGUE are two of the diseases that can be transmitted by species of this genus.
A superfamily of nematodes of the suborder SPIRURINA. Its organisms possess a filiform body and a mouth surrounded by papillae.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Members of the phylum Arthropoda, composed of organisms having a hard, jointed exoskeleton and paired jointed legs. It includes the class INSECTS and the subclass ARACHNIDA, many species of which are important medically as parasites or as vectors of organisms capable of causing disease in man.
The genetic complement of an insect (INSECTS) as represented in its DNA.
The number of males per 100 females.
Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species.
The relationships of groups of organisms as reflected by their genetic makeup.
An inactive stage between the larval and adult stages in the life cycle of insects.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Specialized cells in the invertebrates that detect and transduce light. They are predominantly rhabdomeric with an array of photosensitive microvilli. Illumination depolarizes invertebrate photoreceptors by stimulating Na+ influx across the plasma membrane.
Hormones secreted by insects. They influence their growth and development. Also synthetic substances that act like insect hormones.
One of the largest orders of mostly marine CRUSTACEA, containing over 10,000 species. Like AMPHIPODA, the other large order in the superorder Peracarida, members are shrimp-like in appearance, have sessile compound eyes, and no carapace. But unlike Amphipoda, they possess abdominal pleopods (modified as gills) and their bodies are dorsoventrally flattened.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Organs and other anatomical structures of non-human vertebrate and invertebrate animals.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
An extensive order of highly specialized insects including bees, wasps, and ants.
The process of germ cell development in the female from the primordial germ cells through OOGONIA to the mature haploid ova (OVUM).
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
The capacity to conceive or to induce conception. It may refer to either the male or female.
The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.
A genus of mosquitoes (CULICIDAE) commonly found in tropical regions. Species of this genus are vectors for ST. LOUIS ENCEPHALITIS as well as many other diseases of man and domestic and wild animals.
The total process by which organisms produce offspring. (Stedman, 25th ed)
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
A plant genus of the family MORACEAE. It is the source of the familiar fig fruit and the latex from this tree contains FICAIN.
Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.
The class Insecta, in the phylum ARTHROPODA, whose members are characterized by division into three parts: head, thorax, and abdomen. They are the dominant group of animals on earth; several hundred thousand different kinds having been described. Three orders, HEMIPTERA; DIPTERA; and SIPHONAPTERA; are of medical interest in that they cause disease in humans and animals. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p1)
The interactions between a host and a pathogen, usually resulting in disease.
The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.
The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.
A proto-oncogene protein and member of the Wnt family of proteins. It is expressed in the caudal MIDBRAIN and is essential for proper development of the entire mid-/hindbrain region.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
A nutritional reservoir of fatty tissue found mainly in insects and amphibians.
Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
Any method used for determining the location of and relative distances between genes on a chromosome.
Family of spider MITES, in the superfamily Tetranychoidea, suborder Trombidiformes.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
A steroid hormone that regulates the processes of MOLTING or ecdysis in insects.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Prominent lobed neuropils found in ANNELIDA and all ARTHROPODS except crustaceans. They are thought to be involved in olfactory learning and memory.
The normal length of time of an organism's life.
Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.
A genus of parasitic nematodes whose organisms live and breed in skin and subcutaneous tissues. Onchocercal microfilariae may also be found in the urine, blood, or sputum.
A layer of cells lining the fluid-filled cavity (blastocele) of a BLASTULA, usually developed from a fertilized insect, reptilian, or avian egg.
In a prokaryotic cell or in the nucleus of a eukaryotic cell, a structure consisting of or containing DNA which carries the genetic information essential to the cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
Specialized organs adapted for the reception of stimuli by the NERVOUS SYSTEM.
Genotypic differences observed among individuals in a population.
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Any blood or formed element especially in invertebrates.
The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.
The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)
Structures within the CELL NUCLEUS of insect cells containing DNA.
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The female sex chromosome, being the differential sex chromosome carried by half the male gametes and all female gametes in human and other male-heterogametic species.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Use of naturally-occuring or genetically-engineered organisms to reduce or eliminate populations of pests.
Insects that transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.
Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
A species of parasitic nematodes widely distributed throughout central Africa and also found in northern South America, southern Mexico, and Guatemala. Its intermediate host and vector is the blackfly or buffalo gnat.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Slender-bodies diurnal insects having large, broad wings often strikingly colored and patterned.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.
A mature haploid female germ cell extruded from the OVARY at OVULATION.
A large order of insects characterized by having the mouth parts adapted to piercing or sucking. It is comprised of four suborders: HETEROPTERA, Auchenorrhyncha, Sternorrhyncha, and Coleorrhyncha.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
"Asymmetrical Reinforcement and Wolbachia Infection in Drosophila". PLOS Biology. 4 (10): e325. doi:10.1371/journal.pbio.0040325 ...
It is also used in Wolbachia cell stain in Drosophila melanogaster.[citation needed] Giemsa stain is a classic blood film stain ...
"Association between Wolbachia and Spiroplasma within Drosophila neotestacea: an emerging symbiotic mutualism?". Molecular ... Beyond Drosophila, Spiroplasma of the apis, chrysopicola, citri, mirum, and poulsonii clades are found in many insects and ... The S. poulsonii strain of Drosophila melanogaster can also attack parasitoid wasps, but is not regarded as a primarily ... The S. poulsonii strain of Drosophila neotestacea protects its host against parasitic nematodes. This interaction is an example ...
"The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster". PLOS Biology. 6 (12): ... Ashburner has unique standing as a scholar and authority in the whole area of Drosophila research." "ASHBURNER, Prof. Michael ... Ashburner, Michael; Golic, Kent G.; Hawley, R. Scott (2005), Drosophila : a laboratory handbook (1st ed.), Plain View, N.Y.: ... Michael Ashburner (2006). Won for all: how the Drosophila genome was sequenced. Plainview, N.Y: Cold Spring Harbor Laboratory ...
An example of vertical transmission is seen in Drosophila melanogaster and its Wolbachia spp. symbionts. Corals have been found ...
This implies that Wolbachia establishes itself early in the females in order to ensure its transfer into further hosts, at the ... to Drosophila simulans (Diptera: Drosophilidae)". Heredity. 82 (2): 163-169. doi:10.1038/sj.hdy.6884610. Gottlieb, Yuval; ... Wolbachia is a cytoplasmically inherited intracellular bacterium. It can generally be found in the reproductive organs of its ... However, the bacterium, Wolbachia, has evolved with this species of wasp through vertical transfer to induce irreversible ...
Robert L. Glaser and Mark A. Meola investigated Wolbachia-induced resistance to West Nile virus (WNV) in Drosophila ... Glaser, Robert L.; Meola, Mark A. (2010-08-05). "The Native Wolbachia Endosymbionts of Drosophila melanogaster and Culex ... The WNV-resistance phenotype was then reversed by curing the fruit flies of Wolbachia. Since Wolbachia is also maternally ... Flies infected with Wolbachia were found to have a changed phenotype that caused resistance to WNV. The phenotype was found to ...
Wolbachia, a parasitic bacterial genus that affects a vast array of arthropod species such as Drosophila simulans, is common in ... Wolbachia causes speciation through reproductive isolation. Some hosts evolve with a dependency on Wolbachia for reproductive ... Wolbachia's main method of spreading is to be passed down through the generations in germ line tissues, but it is also capable ... Wolbachia species have been detected in many species of the Phytoseiidae, both in the field and in the lab. Although most ...
Maintenance of a male-killing Wolbachia in Drosophila innubila by male-killing dependent and male-killing independent ... Drosophila quinaria species group Mushroom-feeding Drosophila Jaenike, J. (1978). "An hypothesis to account for the maintenance ... known for his extensive work on mushroom-feeding Drosophila and the evolution of their inherited bacterial symbionts Wolbachia ... 2015). Keith Gull (ed.). "Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association". ...
... tabida is commensally infected with Wolbachia, and cannot reproduce in the absence of Wolbachia infection. As such, the ... The genus is best known for the Drosophila parasitoid Asobara tabida, which is notable as both a model for parasitoid wasp ... "Evolutionary interactions between Drosophila melanogaster and its parasitoid Asobara tabida." Heredity85.5 (2000): 450-458. ... "Host preference and survival in selected lines of a Drosophila parasitoid, Asobara tabida." Journal of Evolutionary Biology ...
January 2006). "Influence of Antibiotic Treatment and Wolbachia Curing on Sexual Isolation Among Drosophila melanogaster Cage ... Research in 2005 has shown that this rapid evolution of reproductive isolation may in fact be a relic of infection by Wolbachia ... William R. Rice and George W. Salt bred Drosophila melanogaster fruit flies using a maze with three different choices of ... Dodd, Diane M. B. (September 1989). "Reproductive Isolation as a Consequence of Adaptive Divergence in Drosophila pseudoobscura ...
This sensitivity is due to infection with σ (Sigma) virus, a rhabdovirus only capable of infecting Drosophila. Although this ... process is usually associated with viruses, recent research has shown that the Wolbachia bacterium is also capable of inserting ... Heritable traits that result from infection with foreign particles have also been identified in Drosophila. Wild-type flies ... the Hereditary CO2 Sensitivity Agent of Drosophila:Nucleotide Sequence of a cDNA Clone Encoding the Glycoprotein". Journal of ...
The relationship between Wolbachia and its host might not have always been mutualistic, as Drosophila populations once ... Wolbachia infection are the most common infection in arthropods today, and over 40% of arthropods have contracted it. Wolbachia ... rapid evolution of Wolbachia in natural populations of Drosophila". PLOS Biology. 5 (5): e114. doi:10.1371/journal.pbio.0050114 ... but without the Wolbachia infection. Wolbachia can also be used to transfer certain genes into the population to further ...
Kondo N, Nikoh N, Ijichi N, Shimada M, Fukatsu T (October 2002). "Genome fragment of Wolbachia endosymbiont transferred to X ... The researchers estimated that for some nematodes and Drosophila insects these genes had been acquired relatively recently. A ... A study found the genomes of 40 animals (including 10 primates, four Caenorhabditis worms, and 12 Drosophila insects) contained ... The adzuki bean beetle has acquired genetic material from its (non-beneficial) endosymbiont Wolbachia. New examples have ...
"Wolbachia utilizes host microtubules and Dynein for anterior localization in the Drosophila oocyte" PLOS Pathog 1 (2), e14 ( ... "Somatic stem cell niche tropism in Wolbachia" Nature 441 (7092), 509-512 (2006) PM Ferree, HM Frydman, JM Li, J Cao, E ...
"Wolbachia and the evolution of reproductive isolation between Drosophila recens and Drosophila subquinaria" (PDF), Evolution, ... This is the case for the hybridization between females of Drosophila simulans and Drosophila melanogaster males: the hybridized ... "Natural selection for reproductive isolation between Drosophila pseudoobscura and Drosophila persimilis", Evolution, 4 (2): 135 ... In some Drosophila crosses, the swelling of the female's vagina has been noted following insemination. This has the effect of ...
... has also played an important role in sequencing the genomes for certain Wolbachia strains. D. simulans eggs ... Wolbachia infections give insight into how certain species of Drosophila are related. Through the analysis of cytoplasmic ... Rousset, F.; Solignac, M. (July 1995). "Evolution of single and double Wolbachia symbioses during speciation in the Drosophila ... Rousset, F.; Solignac, M. (1995). "Evolution of single and double Wolbachia symbioses during speciation in the Drosophila ...
... can harbour bacterial symbionts including Wolbachia and notably Spiroplasma poulsonii. The S. poulsonii ... Drosophila neotestacea is a member of the Testacea species group of Drosophila. Testacea species are specialist fruit flies ... Play media Drosophila neotestacea and other mushroom-breeding Drosophila have been studied extensively for their interactions ... This loss of Diptericin B is also common to the related Drosophila testacea and Drosophila guttifera, but not the also-related ...
... is stably infected by a strain of male-killing Wolbachia bacteria. The association between Drosophila ... Drosophila innubila is a kind of mushroom-breeding Drosophila, and member of the Drosophila quinaria species group. Drosophila ... Unckless RL, Jaenike J (March 2012). "Maintenance of a male-killing Wolbachia in Drosophila innubila by male-killing dependent ... However, their relationship is very consistent across the overall Drosophila innubila species. Male-killing by these Wolbachia ...
For instance, infections of nematodes or of arthropods, including Drosophila, species of the rickettsial bacteria Wolbachia can ... Rubin, Gerald M., Lewis, Edward B.. A Brief History of Drosophila's Contributions to Genome Research (in The Drosophila Genome ... In the off-spring of crosses between Drosophila simulans and its island derivative Drosophila mauritiana, female hybrids are ... Kornberg, Thomas B., Krasnow, Mark A. The Drosophila Genome Sequence: Implications for Biology and Medicine (in The Drosophila ...
Wolbachia is a widespread bacterium that infects insect's organs, most commonly the reproductive organs. Wolbachia has been ... They can be considered the Drosophila of the parasitoid world, as they have been used for inundative releases and much of our ... However, when looking at the Wolbachia-host associations, the Trichogramma-Wolbachia form a monophyletic group based on several ... Finally, Wolbachia can influence gender determination in its hosts so that more females are successfully born. This results in ...
"Wolbachia and the Evolution of Reproductive Isolation Between Drosophila Recens and Drosophila Subquinaria". Evolution; ... This benefits the Wolbachia as they are passed on from mothers to their offspring. Drosophila recens is commonly infected with ... Drosophila bizonata, and Drosophila testacea species groups. Evolutionary studies in these various mushroom-feeding Drosophila ... Drosophila innubila is a species commonly infected with a Wolbachia bacterial endosymbiont that causes male-killing. Male- ...
... infection has been linked to viral resistance in Drosophila melanogaster, Drosophila simulans, and mosquito species. ... "Wolbachia" at the Encyclopedia of Life The Wolbachia Project at Vanderbilt University Images of Wolbachia. ... Wolbachia, especially Wolbachia-caused cytoplasmic incompatibility, may be important in promoting speciation. Wolbachia strains ... In Drosophila melanogaster, Wolbachia is found to mediate iron metabolism under nutritional stress and in Cimex lectularius, ...
The exact mechanisms of how Wolbachia perform modification and rescue are unknown. In Drosophila, the earliest effects caused ... As Wolbachia are only transmitted by females, this mechanism promotes the spread of Wolbachia and therefore keeps Wolbachia ... CI occurs when a Wolbachia infected male mates with a female that is infected by another Wolbachia strain (bidirectional CI) or ... The populations develop to a point where incompatibility would be maintained even in absence of Wolbachia. Wolbachia are not ...
O primeiro xenoma de Wolbachia que foi determinado foi o da especie que infecta á mosca Drosophila melanogaster.[24] Este ... "The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster". PLOS Biology 6 (12): ... Unha copia case completa do xenoma de Wolbachia encontrouse dentro do xenoma da mosca Drosophila ananassae e grandes segmentos ... As infeccións por Wolbachia foron asociadas coa resistencia viral na mosca Drosophila melanogaster e en especies de mosquitos. ...
In 1989, Dodd reported mating preferences in Drosophila that were induced by diet. It has recently been demonstrated that when ... For example, normal development of female wasps of the species Asobara tabida is dependent on Wolbachia infection. If "cured" ... Leftwich PT, Clarke NV, Hutchings MI, Chapman T (November 2017). "Gut microbiomes and reproductive isolation in Drosophila". ... Dodd DM (September 1989). "REPRODUCTIVE ISOLATION AS A CONSEQUENCE OF ADAPTIVE DIVERGENCE IN DROSOPHILA PSEUDOOBSCURA" (PDF). ...
They concluded that mosquito populations were reduced by about 95%. Fruit flies (Drosophila melanogaster) are model organisms ... Incompatible Insect Technique (IIT) - Wolbachia Maternal Effect Dominant Embryonic Arrest (Medea) X-Shredder There are concerns ... Chintapalli, Venkateswara R.; Wang, Jing; Dow, Julian A. T. (2007-06-01). "Using FlyAtlas to identify better Drosophila ... Powell, Jeffrey R. (1997-01-01). Progress and Prospects in Evolutionary Biology: The Drosophila Model. Oxford University Press ...
Wolbachia is a bacterium commonly present in insect species that can protect their hosts against viruses, including the dengue ... "Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila". Development. 138 (11): 2337-2346 ... Studies on the bacteria Wolbachia conducted by Luis Teixeira and his research group revealed that a single genomic change can ... Chrostek, Ewa; Teixeira, Luis (2015-02-10). "Mutualism Breakdown by Amplification of Wolbachia Genes". PLOS Biology. 13 (2): ...
New research is looking into the use of a bacterium called Wolbachia as a method of biocontrol. Studies show that invasion of ... The sequence indicates the species diverged from Drosophila melanogaster (the common fruit fly) about 250 million years ago, ... has started the Debug Project to infect males of this species with Wolbachia bacteria, interrupting the reproductive cycle of ... Dutra, HL; Rocha, MN; Dias, FB; Mansur, SB; Caragata, EP; Moreira, LA (June 8, 2016). "Wolbachia Blocks Currently Circulating ...
can be reproductive manipulators, but also defensive symbionts of Drosophila flies. In Drosophila neotestacea, S. poulsonii has ... These symbioses affect organisms with global impact, including Symbiodinium of corals, or Wolbachia of insects. Many insect ... Hamilton PT, Peng F, Boulanger MJ, Perlman SJ (January 2016). "A ribosome-inactivating protein in a Drosophila defensive ... thrive in their intermediate insect hosts because of an obligate endosymbiosis with Wolbachia spp[citation needed]. They can ...
Separate the name of parasites and hosts with ex., e.g. Wolbachia sp. ex. Drosophila melanogaster ... Avoid using codes for non-redundant names (e.g. write Drosophila melanogaster, not DMelan45GRX). However, it is acceptable ...
K Sterile insect technique and Wolbachia symbiosis as potential tools for the control of the invasive species Drosophila ... Sassu, F; Nikolouli, K; Caravantes, S; Taret, G; Pereira, R; Vreysen, MJB; Stauffer, C; Caceres, C Mass-Rearing of Drosophila ... K Combining sterile and incompatible insect techniques for the population suppression of Drosophila suzukii. ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 1 n/a -. NC_007354 Ecaj_0319 response regulator receiver:ATP- ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 0.19303 n/a -. NC_007760 Adeh_2745 ribose-5-phosphate ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 0.148349 n/a -. NC_009943 Dole_0416 filamentation induced by ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 0.153062 n/a -. NC_003295 RSc3440 DNA gyrase subunit B 60.07 ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 0.604081 n/a -. NC_008576 Mmc1_1573 HflK protein 33.69 ...
Wolbachia endosymbiont of Drosophila melanogaster Bacteria normal 1 n/a -. NC_009719 Plav_3270 alkyl hydroperoxide reductase/ ...
Whats the buzz on somatic Wolbachia infection? Using Drosophila melanogaster as a model organism to understand the control of ...
His current work is focused on the host-microbe interaction between Aedes aegypti and Wolbachia, exploring the mechanisms ... Anopheles gambiae and Drosophila melanogaster as model organisms. ...
Some prominent examples include Ophiocordyceps unilateralis (fungi), Toxoplasma gondii (protista), Wolbachia (bacteria), ... Influence of antibiotic treatment and Wolbachia curing on sexual isolation among Drosophila melanogaster cage populations. ... Some prominent examples include Ophiocordyceps unilateralis (fungi), Toxoplasma gondii (protista), Wolbachia (bacteria), ... The Wolbachia bacteria are widespread parasites of arthropods and nematodes and may influence their hosts mating behavior in a ...
"The foreign within: Drosophila-Spiroplasma interaction as a model of insect endosymbiosis". ... Wolbachia) which are less amenable to genetic studies.. Jeudi. 06/12/2018. 14h ... Surprisingly S. poulsonii cells are neither detected nor affected by the Drosophila immune system, but their proliferation is ... We have also provided strong evidences that the ability of Spiroplasma to protect Drosophila against infestation by parasitoid ...
Wolbachia-infected and Wolbachia-free populations of D. melanogaster were exposed to Drosophila C virus (a natural, and highly ... Wolbachia-infected flies were still substantially more resistant to DCV viruses than their Wolbachia-free counterparts. ... Cancer and loneliness in Drosophila. Drosophila flies may not be perceived as a quintessentially social animal, particularly ... Cancer and loneliness in Drosophila. Drosophila flies may not be perceived as a quintessentially social animal, particularly ...
In Drosophila, the fertilization of uninfected eggs by sperm from Wolbachia-infected males often […] ... Wolbachia are maternally inherited endosymbiontic bacteria that manipulate gamete compatibility in many arthropod species. ... Activation of Arp2/3 by WASp Is Essential for the Endocytosis of Delta Only during Cytokinesis in Drosophila, Cell Rep 2019 Jul ... Regulation of cortical stability by RhoGEF3 in mitotic sensory organ precursor cells in Drosophila, Biol Open 2017 Nov;. ...
He is studying drosophila immunity and fungal pathogenesis.. Citations:. Acuna, R., B. E. Padilla, C. P. Florez-Ramos, J. D. ... Wolbachia is an intracellular bacterial parasite/mutualist with complex host interactions. While LGT from bacteria to animals ... Dunning Hotopps team detected LGT from the bacterial endosymbionts Wolbachia in over 30% of sequenced arthropod genomes. ...
"Wolbachia utilizes host microtubules and Dynein for anterior localization in the Drosophila oocyte.", PLoS Pathog, vol. 1, no. ... H. M. Frydman, Li, J. M., Robson, D. N., and Wieschaus, E., "Somatic stem cell niche tropism in Wolbachia.", Nature, vol. 441, ... "Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition.", Development, vol. 136, no. 12 ...
Belles X: Beyond Drosophila: RNAi in vivo and functional genomics in insects. Annu Rev Entomol. 2010, 55: 111-128. 10.1146/ ... Hussain M, Frentiu FD, Moreira LA, ONeill SL, Asgari S: Wolbachia uses host microRNAs to manipulate host gene expression and ... Chawla G, Sokol NS: Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology ... Sokol NS, Xu P, Jan YN, Ambros V: Drosophila let-7 microRNA is required for remodeling of the neuromusculature during ...
Interests: Evolutionary genetics; Microbial-host interactions with emphasis on Wolbachia in arthropods, genetics of speciation ... Interests: Genetics of ecological adaptation in Drosophila; Evolutionary effects of deleterious mutations; Quantitative-genetic ... Interests: Genetics of speciation in Drosophila; Genetics and theory of adaptation; Population genetics ... Sex chromosome and dot chromosome evolution in Drosophila ...
Phylogenomics and analysis of shared genes suggest a single transition to mutualism in Wolbachia of nematodes. F Comandatore, D ... Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines. PD Keightley, U ...
Next Next post: Wolbachia infections in Aedes aegypti: The Bigfoot of endosymbionts. ... drosophila (7) endosymbionts (21) evolution (19) field work (10) genetic rescue (3) genetics (21) grasshoppers (5) ...
Dyctioptera,Mantidae,Infected by Wolbachia (1) *Erysiphe alphitoides,-induced volatile emissions scale with the degree of ... DMelSV,Incidence in Lines of Drosophila melanogaster Selected for Survival following Infection with Bacillus cereus (1) ...
Drosophila Ephydra Ephydridae Field Work Funding Goodman Hawaiian Drosophila Keys Kidwell Lapoint Limonia Magnacca Marrack ...
Drosophila Ephydra Ephydridae Field Work Funding Goodman Hawaiian Drosophila Keys Kidwell Lapoint Limonia Magnacca Marrack ...
Drosophila Ephydra Ephydridae Field Work Funding Goodman Hawaiian Drosophila Keys Kidwell Lapoint Limonia Magnacca Marrack ...
Drosophila Ephydra Ephydridae Field Work Funding Goodman Hawaiian Drosophila Keys Kidwell Lapoint Limonia Magnacca Marrack ...
Drosophila Ephydra Ephydridae Field Work Funding Goodman Hawaiian Drosophila Keys Kidwell Lapoint Limonia Magnacca Marrack ...
Fraisse, C., Puixeu Sala, G., & Vicoso, B. (2019). Pleiotropy modulates the efficacy of selection in drosophila melanogaster. ... Turelli, M., & Barton, N. H. (2017). Deploying dengue-suppressing Wolbachia: Robust models predict slow but effective spatial ... Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes ...
Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A. 2012 ;109(39):15553-9 ... Comparative Genomics of a Parthenogenesis-Inducing Wolbachia Symbiont. * The DNA sequence, annotation and analysis of human ... Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Res. 2014 ;24( ...
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 2014 ;159(1):200-14. * ... Comparative Genomics of a Parthenogenesis-Inducing Wolbachia Symbiont. * The DNA sequence, annotation and analysis of human ...
Comparative Genomics of a Parthenogenesis-Inducing Wolbachia Symbiont. * The DNA sequence, annotation and analysis of human ...
  • 9 ) found that the bacteria from the mosquito Aedes albopictus , transferred by injection into uninfected embryos of Drosophila simulans , confer complete CI on the adults. (pnas.org)
  • We have characterized this bacterium, by amplifying and sequencing its 16S rRNA gene, as being a member of the genus Wolbachia, an organism that is known to parasitize a range of insects including Drosophila simulans. (nih.gov)
  • To determine whether absence of cytoplasmic incompatibility in D. mauritiana was due to either the bacterial or host genome, we transferred bacteria from D. mauritiana into an uninfected strain of D. simulans, a host species known to express high levels of incompatibility with endogenous Wolbachia. (genetics.org)
  • These experiments indicate that in D. simulans and D. mauritiana expression of the cytoplasmic incompatibility phenotype is determined by the bacterial strain and that D. mauritiana harbors a neutral strain of Wolbachia. (genetics.org)
  • Wolbachia- mediated antiviral protection has been described to occur in Drosophila melanogaster and Drosophila simulans , flies which exhibit delayed mortality when challenged with RNA viruses, including Drosophila C virus (DCV), cricket paralysis virus, Flock House virus, and Nora virus ( 15 , 36 , 39 ). (asm.org)
  • Interestingly, some Wolbachia- containing flies, such as the D. simulans CO line which contains the Wolbachia strain w Au (CO- w Au), were better able to tolerate high titers of virus than Wolbachia- free flies ( 36 ). (asm.org)
  • When five D. simulans - Wolbachia combinations were screened for antiviral protection by viral challenge, three combinations were protected (CO- w Au, Me29- w Mel, and DSR- w Ri), whereas the other two were not (DSH- w Ha and N7NO- w No) ( 36 ). (asm.org)
  • This phenomenon can result in Wolbachia spreading through natural populations as previously demonstrated in Drosophila simulans. (lancs.ac.uk)
  • Here we describe another Wolbachia infection in D. simulans that does not cause cytoplasmic incompatibility. (lancs.ac.uk)
  • Thus our article should be corrected to report that new Wolbachia genome sequences were discovered in D. ananassae and D. simulans , but not in D. mojavensis . (biomedcentral.com)
  • Ballard JWO (2004) Sequential evolution of a symbiont inferred from the host: Wolbachia and Drosophila simulans. (els.net)
  • For example, they enable the Wolbachia strain infecting one species of fruit fly, Drosophila simulans , to maintain a stable 94% rate of infection in natural populations, even though an estimated 2.5% of the eggs are not infected. (asmblog.org)
  • Drosophila simulans is a species of fly closely related to D. melanogaster, belonging to the same melanogaster species subgroup. (wikipedia.org)
  • Drosophila simulans was found later to be closely related to two island endemics, D. sechellia and D. mauritiana. (wikipedia.org)
  • Cytoplasmic incompatibility causes egg and sperm cells to fail in creating viable offspring, a common feature in Wolbachia-infected D. simulans and D. mauritiana individuals. (wikipedia.org)
  • Infections of Wolbachia, a commonly infectious strain of bacteria observed in many insects such as Trichogramma and Muscidifurax uniraptor wasps, are transmitted between generations of Drosophila simulans. (wikipedia.org)
  • Wolbachia has formed a symbiotic relationship with D. simulans. (wikipedia.org)
  • Two separate Wolbachia infection events have occurred in the ancestors of D. simulans, suggesting the evolutionary advantage of Wolbachia infections to D. simulans. (wikipedia.org)
  • Wolbachia infections have significantly decreased virus-induced mortality in D. simulans. (wikipedia.org)
  • Drosophila simulans has also played an important role in sequencing the genomes for certain Wolbachia strains. (wikipedia.org)
  • D. simulans eggs were infected with the wRi Wolbachia strain in order to better understand how Wolbachia recombines. (wikipedia.org)
  • Further studies can help understand how Wolbachia strains coexist with D. simulans individuals. (wikipedia.org)
  • Drosophila pseudoobscura (X-linked meiotic driver genes causing female biased sex ratios) and D. melanogaster and D. simulans (the cytoplasmic maternally inherited bacterium Wolbachia causing reduced hatching success, CI). (exeter.ac.uk)
  • Wolbachia are known, in various species, to cause cytoplasmic incompatibility (CI): crosses between bacteria-infected males and uninfected females produce few offspring, whereas infected females, due to an unknown mechanism, are resistant and produce ample progeny ( 3 , 4 ). (pnas.org)
  • The bacteria have been reported in a number of Drosophila species, associated with varied degrees of CI, including only weak or no effects ( 10 - 14 ). (pnas.org)
  • Wolbachia are widespread maternally transmitted intracellular bacteria that infect most insect species and are able to alter the reproduction of innumerous hosts. (sciencemag.org)
  • Wolbachia bacteria are best known for their ability to manipulate host reproductive systems, leading to an increase in their frequency within insect populations over successive generations ( 20 , 35 , 40 , 44 ). (asm.org)
  • We have recently described a mutualistic symbiosis in which Wolbachia bacteria were shown to improve the fitness of some Drosophila melanogaster stocks. (semanticscholar.org)
  • To better understand how bacteria maintain symbiotic associations with animal hosts, we analyzed genome-wide gene expression for the endosymbiotic α-proteobacteria Wolbachia pipientis across the entire life cycle of Drosophila melanogaster . (g3journal.org)
  • Endosymbiotic Wolbachia bacteria use a conceptually similar strategy, associating with host germline determinants that promote inclusion of Wolbachia into maternal germline cells ( Serbus and Sullivan, 2007 ). (biologists.org)
  • The intracellular bacteria Wolbachia infect up to 40% of all insect species, including the vectors of prevalent infectious diseases such as Dengue and malaria. (bu.edu)
  • To investigate the role of the host cytoskeleton in the maternal transmission of the endoparasitic bacteria Wolbachia, we have characterized their distribution in the female germ line of Drosophila melanogaster. (princeton.edu)
  • During mid-oogenesis, Wolbachia exhibit a distinct concentration between the anterior cortex and the nucleus in the oocyte, where many bacteria appear to contact the nuclear envelope. (princeton.edu)
  • In live egg chambers, Wolbachia exhibit movement in nurse cells but not in the oocyte, suggesting that the bacteria are anchored by host factors. (princeton.edu)
  • In animals, most of the LGT events identified as originating from bacteria have occurred between Wolbachia bacteria and their various hosts. (biomedcentral.com)
  • Wolbachia are endosymbiont bacteria of the family Rickettsiacea that are widespread in invertebrates and occur between 20% and 60% of Neotropical insects. (scielo.br)
  • Wolbachia are intracellular obligatory bacteria of the family Rickettsiacea that occur in a wide range of arthropods and nematodes. (scielo.br)
  • The presence of Wolbachia in Anastrepha is therefore of considerable interest since these bacteria may be exploited as biological controls of pest insects, as suggested by Bourtzis (1). (scielo.br)
  • The widespread bacteria known to manipulate host reproductive output can do so by ramping up stem cell division and consequent egg production in Drosophila . (the-scientist.com)
  • Wolbachia are widespread bacteria that infect a variety of invertebrate species. (the-scientist.com)
  • Different strains of Wolbachia can cause infected males to produce sperm that kills uninfected eggs, induce parthenogenesis in infected females-eliminating the need for reproductive mating-and can even turn males into functional females that can pass the bacteria on to their offspring. (the-scientist.com)
  • To understand how Wolbachia induce this increase in egg production, Frydman's team examined the distribution of the bacteria inside flies infected with a Wolbachia strain called w Mau. (the-scientist.com)
  • The distribution of these bacteria in the Drosophila ovarian cells at different stages of oogenesis has been amply described. (biomedcentral.com)
  • Dedeine F, Vavre F, Fleury F, Loppin B, Hochberg ME, Bouletreau M (2001) Removing symbiotic Wolbachia bacteria specifically inhibits oogenesis in a parasitic wasp. (springer.com)
  • Evolutionary studies in these various mushroom-feeding Drosophila have contributed to understanding how symbiotic bacteria can drastically affect host evolution, the impact of various genetic elements in natural populations, and speciation. (wikipedia.org)
  • Specifically, we determined whether dietary nutrients affect the amount of Wolbachia bacteria carried by female flies. (prolekare.cz)
  • Varias especies son tan dependentes de Wolbachia , que non se poden reproducir se non teñen a bacteria nos seus corpos, e algunhas mesmo non poderían sobrevivir sen a bacteria. (wikipedia.org)
  • As moscas infectadas pola bacteria son máis resistentes a virus de ARN como o virus de Drosophila C , Nora virus , nodavirus Flock house, virus da parálise do grilo , virus Chikungunya , e virus do Nilo occidental . (wikipedia.org)
  • [ 21 ] No insecto Phyllonorycter blancardella (unha couza minadora de folas), a bacteria Wolbachia axuda aos hóspedes a producir áreas illadas verdes en follas de árbore que están amarelando, o que permite aos adultos continuar alimentándose mentres crecen ata converterse en formas adultas. (wikipedia.org)
  • New research shows that Drosophila flies infected with Wolbachia bacteria fare better than uninfected flies against several killer viruses. (newscientist.com)
  • Prevalence and diversity of Wolbachia bacteria infecting insect pests of stored products , 62 93-100. (gc.ca)
  • Review of treatment methods to remove Wolbachia bacteria from arthropods. (gc.ca)
  • Wolbachia are endosymbiotic bacteria that commonly infect arthropods, inducing certain phenotypes in their hosts. (scielo.br)
  • Wolbachia are maternally transmitted alpha-proteo-bacteria known to infect a wide range of arthropods and nematodes, where they can be found in either germ line or somatic tissues (Bandi et al . (scielo.br)
  • Mating insects infected with different strains of Wolbachia bacteria can also result in embryonic lethality 13 . (nature.com)
  • Forty-one stocks from 30 Drosophila species were surveyed for Wolbachia infection using PCR technology. (genetics.org)
  • Wolbachia , a maternally transmitted microorganism of the Rickettsial family, is known to cause cytoplasmic incompatibility, parthenogenesis, or feminization in various insect species. (pnas.org)
  • Wolbachia can be transferred by injection, within or between species ( 8 ). (pnas.org)
  • which is present in up to 40% of all insect species, has the ability to alter viral dynamics in both Drosophila spp. (asm.org)
  • Wolbachia is a maternally transmitted bacterium which is predicted to infect up to 70% of insect species ( 17 , 24 , 45 ). (asm.org)
  • Drosophila melanogaster and its close relatives have been extremely important model species in the development of population genetic models that serve to explain patterns of diversity in natural populations, a major goal of evolutionary biology. (nih.gov)
  • Wolbachia endosymbionts are globally dispersed throughout most insect species and are the causative agent in filarial nematode-mediated disease. (biologists.org)
  • As part of ongoing efforts to characterize complete genome sequences of microbial symbioints of Drosophila species, the Bergman Lab has been involved in mining complete genomes of the Wolbachia endosymbiont from whole-genome shotgun sequences of D. melanogaster . (uga.edu)
  • This work is inspired by Steve Salzberg and colleagues' pioneering paper in 2005 showing that Wolbachia genomes can be extracted from the whole-genome shotgun sequence assemblies of Drosophila species. (uga.edu)
  • The Neotropical fruit fly Drosophila paulistorum (Diptera: Drosophilidae) is a species complex in statu nascendi comprising six reproductively isolated semispecies, each harboring mutualistic Wolbachia strains. (biomedcentral.com)
  • Some of the functions associated with differentially expressed genes are known to be affected by Wolbachia in other species, such as metabolism and immunity, whereas others represent putative novel phenotypes involving muscular functions, pheromone signaling, and visual perception. (biomedcentral.com)
  • Wolbachia is a maternally inherited endosymbiont that is commonly found in insects, including a number of mosquito vector species. (mdpi.com)
  • This review outlines research on the prevalence of Wolbachia in mosquito vector species and the impact of antiviral effects in both naturally and artificially Wolbachia-infected mosquitoes. (mdpi.com)
  • We infected flies with two positive sense RNA viruses known to replicate in a range of Drosophila species (Drosophila C virus and Flock House virus) and measure the rate of death in Wolbachia positive and negative host lines with the same genetic background. (biomedcentral.com)
  • nov., a new species associated with male-lethality in Drosophila willistoni , a neotropical species of fruit fly. (nature.com)
  • On searching the D. willistoni traces, a substantial Wolbachia infection in this species was discovered and 2,291 sequences belonging to Wolbachia were found. (biomedcentral.com)
  • Salzberg SL, Dunning Hotopp JC, Delcher AL, Pop M, Smith DR, Eisen MB, Nelson WC: Serendipitous discovery of Wolbachia genomes in multiple Drosophila species. (biomedcentral.com)
  • The intracellular bacterial parasites of the genus Wolbachia are widespread among arthropod species. (hu-berlin.de)
  • Finally, (iv) we apply our models to a particular real-world speciation process of two sibling Drosophila species in North America, discuss emerging problems, and suggest future directions of research. (hu-berlin.de)
  • Now, I believe Wolbachia is tied into what is happening to vertebrate species (including North Atlantic right whales, Adelie penguins, and even humans). (infobarrel.com)
  • Wolbachia is like Dr. Jekyll and Mr. Hyde depending on the species that acquires it. (infobarrel.com)
  • Wolbachia are bacterial endosymbionts of many arthropod species in which they manipulate reproductive functions. (biomedcentral.com)
  • Here, using the model species Drosophila melanogaster , we used a combination of Genome Wide Association mapping (GWAS) and transcriptomic profiling to characterize whether genes associated with thermal tolerance are primarily involved in dynamic stress responses or preparatory processes that influence physiological condition at the time of thermal stress. (frontiersin.org)
  • Note that removal of Wolbachia by antibiotic treatment results in the loss of CI showing that the infected populations are indeed the same species. (els.net)
  • Calabria G, Máca J, Bächli G, Serra L, Pascual M (2010) First records of the potential pest species Drosophila suzukii (Diptera: Drosophilidae) in Europe. (springer.com)
  • Heath BD, Butcher RD, Whitfield WG, Hubbard SF (1999) Horizontal transfer of Wolbachia between phylogenetically distant insect species by a naturally occurring mechanism. (springer.com)
  • Here, we used the MultiLocus Sequence Typing system, to identify and characterize five Wolbachia strains infecting several species within the Nanos clypeatus dung beetle clade. (frontiersin.org)
  • The Drosophila quinaria species group is a speciose lineage of mushroom-feeding flies studied for their specialist ecology, their parasites, population genetics, and the evolution of immune systems. (wikipedia.org)
  • Quinaria species are part of the Drosophila subgenus. (wikipedia.org)
  • Quinaria group species such as Drosophila falleni are attracted to mushroom sites by cuing in on specific odourants that are common in rotting mushrooms, such as 1-pentanol, 1-octen-3-ol, and 3-methyl-1-butanol. (wikipedia.org)
  • Quinaria species are related to the Drosophila cardini, Drosophila bizonata, and Drosophila testacea species groups. (wikipedia.org)
  • In September 2020, a study of Drosophila sex pheromone communication sequenced the genomes of D. quinaria, and D. palustris, as well as many outgroup lineages of the Quinaria species group. (wikipedia.org)
  • One method to study these patterns has been to compare gene regulation amongst different Drosophila species. (wikipedia.org)
  • Wolbachia are obligate intracellular endosymbionts carried by an estimated 40% of all insect species, including the established model organism Drosophila melanogaster [ 17 - 20 ]. (prolekare.cz)
  • Wolbachia infections give insight into how certain species of Drosophila are related. (wikipedia.org)
  • Drosophila sechellia has significantly distinct mitochondrial DNA, further emphasizing the evolutionary differences between the three species. (wikipedia.org)
  • Wolbachia - which plagues two-thirds of all insect species - is best known for its gender-bending effects . (newscientist.com)
  • He wonders whether other insects experience the same benefit from Wolbachia infection, noting that the bacteria's effect on most insect species remains unknown. (newscientist.com)
  • So far, no endemic South American species of terrestrial isopods have been investigated for Wolbachia infection. (scielo.br)
  • Wolbachia found in both species were generally specific to one population, and five populations hosted two different Wolbachia 16S rDNA sequences. (scielo.br)
  • AMOVA analyses showed that most of the genetic variance was distributed among populations of each species rather than between species, and the phylogenetic analysis suggested that Wolbachia strains from Balloniscus cluster within Supergroup B, but do not form a single monophyletic clade, suggesting multiple infections for this group. (scielo.br)
  • Our results highlight the importance of studying Wolbachia prevalence and genetic diversity in Neotropical species and suggest that South American arthropods may harbor a great number of diverse strains, providing an interesting model to investigate the evolution of Wolbachia and its hosts. (scielo.br)
  • Terrestrial isopod species (Crustacea, Oniscidea) are widely infected with Wolbachia with prevalence reaching ~61% (~36 infected species) in this group (Bouchon et al . (scielo.br)
  • In both studies, the authors observed that the overall prevalence of Wolbachia was higher than that found in other studies in France with the same species (Cordaux et al . (scielo.br)
  • Wolbachia infects several species of mosquitoes, but none of the ones that cause human diseases. (discovermagazine.com)
  • Maybe Drosophila species which integrated different amounts of Wolbachia naturally or experimentally could be a start. (blogspot.com)
  • Wolbachia infections and the expression of cytoplasmic incompatibility in Drosophila sechellia and D. mauritiana. (genetics.org)
  • Various stocks of Drosophila mauritiana and D. sechellia were found to be infected with Wolbachia, a Rickettsia-like bacterium that is known to cause cytoplasmic incompatibility and other reproductive abnormalities in arthropods. (genetics.org)
  • In some situations Wolbachia confer a selective advantage upon infected females by inducing parthenogenesis, feminization of males, male-killing or sperm-egg cytoplasmic incompatibility. (biologists.org)
  • Microbes of the genus Wolbachia are transmitted by their hosts via the maternal parent and are responsible for cytoplasmic incompatibility among insect populations. (lancs.ac.uk)
  • It has recently been found that this is the case for some strains of Wolbachia , which both cause cytoplasmic incompatibility and protect their hosts against viruses. (biomedcentral.com)
  • Text-book examples include the association between Wolbachia strains inducing cytoplasmic incompatibility (CI) in their hosts. (frontiersin.org)
  • The infection is maintained through a process involving cytoplasmic incompatibility (CI) in which Wolbachia hinders uninfected individuals from producing offspring. (wikipedia.org)
  • Unidirectional cytoplasmic incompatibility (CI) results in a postfertilization incompatibility between Wolbachia -infected males and uninfected females. (asm.org)
  • The popcorn Wolbachia infection of Drosophila melanogaster: can selection alter Wolbachia longevity effects? (nih.gov)
  • Wolbachia popcorn (wMelPop), a life-shortening strain of Wolbachia, has been proposed as an agent for suppressing transmission of dengue fever following infection of the vectoring mosquito Aedes aegypti. (nih.gov)
  • This divergence was mostly associated with the host genetic background rather than the Wolbachia infection, although there were also interactions between the host and Wolbachia genomes. (nih.gov)
  • To understand the potential effect of Wolbachia on viral dynamics in nature, it is important to consider the impact of natural routes of virus infection on Wolbachia antiviral effects. (asm.org)
  • Using adult Drosophila strains, we show here that Drosophila - Wolbachia associations that have previously been shown to confer antiviral protection following systemic viral infection also confer protection against virus-induced mortality following oral exposure to Drosophila C virus in adults. (asm.org)
  • The differences in the outcome of virus infection are likely to influence viral dynamics in Wolbachia -infected insect populations in nature and could also have important implications for the transmission of arboviruses in mosquito populations. (asm.org)
  • on virus infection was first described in the Drosophila melanogaster host, where it was shown to protect against mortality induced by diverse viruses, including Drosophila C virus (DCV), cricket paralysis virus, and Flock House virus ( 2 , 3 ). (asm.org)
  • The impact of the presence of Wolbachia on virus infection can include two main effects: (i) interference with viral replication/accumulation, and/or (ii) protection against virus-induced mortality. (asm.org)
  • Wolbachia infection leads to an increase in the mitotic activity of germline stem cells (GSCs), as well as a decrease in programmed cell death in the germarium. (sciencemag.org)
  • Yet, Wolbachia abundance has been shown to vary greatly between individuals and the magnitude of the effects of infection on host life-history traits and protection against infection is correlated to within-host Wolbachia abundance. (lancs.ac.uk)
  • It is not yet understood how the presence of Wolbachia delays virus accumulation or how it contributes to host tolerance of viral infection. (asm.org)
  • We also investigated the prevalence of infection with the bacterial endosymbiont Wolbachia. (nih.gov)
  • Populations from Sub-Saharan Africa also differ in the prevalence of Wolbachia infection, with very low levels of infection compared to populations from the rest of the world. (nih.gov)
  • These findings suggest that the Wolbachia infection behaves like a neutral variant in populations. (lancs.ac.uk)
  • The infection may represent an evolutionary outcome of interactions between Wolbachia infections and their hosts. (lancs.ac.uk)
  • Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti , Science , 2009, vol. 323, pp. 141-144. (springer.com)
  • wMel-like and wMelCS-like Wolbachia strains differ in their frequencies and densities of hub infection. (bu.edu)
  • Early studies suggested that the reproductive incompatibility observed in D. paulistorum was due to a microbial infection [ 11 , 12 ], but it was only recently determined that the microbe in question is Wolbachia [ 8 ]. (biomedcentral.com)
  • Firstly, we discuss how Wolbachia and viruses both require specific host-derived structures, compounds, and processes to initiate and maintain infection. (mdpi.com)
  • There is significant overlap in these requirements, and infection with either microbe often manifests as cellular stress, which may be a key component of Wolbachia 's anti-viral effect. (mdpi.com)
  • Recent studies have shown that virus infection and transmission in insects can be impeded by co-infection with the bacterium Wolbachia pipientis. (mdpi.com)
  • Here, we report a further characterization of the phenotypic effects of this virulent Wolbachia infection on several life-history traits of Ae. (nih.gov)
  • We thank Therese Markow of the University of Arizona for bringing this error in the Trace Archive data to our attention, and Jack Werren of the University of Rochester for suggesting that D. willistoni might have a Wolbachia infection. (biomedcentral.com)
  • In the germarium, Wolbachia are distributed to all germ cells of the cyst, establishing an early infection in the cell destined to become the oocyte. (princeton.edu)
  • In this thesis, we analyze common criticisms of such a role by means of mathematical models, combining Wolbachia infection dynamics and host population genetics. (hu-berlin.de)
  • The ovary of fruit fly with Wolbachia (yellow) parasitic infection (left) compared to an ovary without an infection (right). (kenyon.edu)
  • Infection with Wolbachia is known to induce diploidization of haploid eggs and enables the production of females from unfertilized eggs. (springer.com)
  • We also examined the infection rate of the recipients due to cannibalism of Wolbachia -infected pupae. (springer.com)
  • Cordaux R, Michel-Salzat A, Bouchon D (2001) Wolbachia infection in crustaceans: novel hosts and potential routes for horizontal transmission. (springer.com)
  • Small Things Considered: Wolbachia Infection: A Good Thing? (asmblog.org)
  • Wolbachia Infection: A Good Thing? (asmblog.org)
  • Might it be that Wolbachia infection prevents deleterious infections by other organisms? (asmblog.org)
  • Thus, the Wolbachia protects the insects from serious infection by this fungus. (asmblog.org)
  • Both field and lab populations typically show 30-40% infection by DCV, the Drosophila C virus . (asmblog.org)
  • So, are the Wolbachia doing their Drosophila hosts a favor by defending them against DCV infection? (asmblog.org)
  • Using a natural system, we explore the effects of a Wolbachia-Plasmodium co-infection on mosquito fecundity. (cambridge.org)
  • Wolbachia , on the other hand, increases fecundity by roughly 10%, but does not alter the tolerance (fecundity-burden relationship) of mosquitoes to Plasmodium infection. (cambridge.org)
  • Our results showed a low Wolbachia infection rate and inferred the detected strains belong to either supergroups A and B. (biomedcentral.com)
  • Studying Wolbachia strains and their mechanisms of infection can provide insight into the complex phylogenetic relationships of arthropods. (wikipedia.org)
  • While hunting for genes that protected Drosophila from viral infection in general, she found a virus-resistant fly strain that turned out to be infected with Wolbachia . (newscientist.com)
  • Due to the non-cultivable nature of Wolbachia , the most common method for detecting infection is the enzymatic amplification of one or more Wolbachia gene fragments (O'Neill et al . (scielo.br)
  • The type of Wolbachia infection determines its effect on Drosophila melanogaster female fecundity via metabolism of juvenile hormone. (biologists.org)
  • Effects of Wolbachia infection and ovarian tumor mutations on Sex-lethal germline functioning in Drosophila. (berkeley.edu)
  • Somatic Wolbachia (Rickettsiales: Rickettsiaceae) levels in Culex quinquefasciatus and Culex pipiens (Diptera: Culicidae) and resistance to West Nile Virus infection. (wadsworth.org)
  • The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infection. (wadsworth.org)
  • West Nile virus infection of Drosophila melanogaster induces a protective RNAi response. (wadsworth.org)
  • Here, we report that Drosophila mauritiana infected with a native Wolbachia w Mau strain produces about four times more eggs than the noninfected counterpart. (sciencemag.org)
  • Characterization of Wolbachia in the N271 strain. (asm.org)
  • In this study, to further investigate the relationship between whole-fly Wolbachia density and the ability to mediate antiviral protection, tetracycline was used to decrease the abundance of the high-density, protective Wolbachia strain w Au prior to viral challenge. (asm.org)
  • Antiviral protection was lost when the density of the protective Wolbachia strain was decreased to an abundance similar to that of nonprotective Wolbachia strains. (asm.org)
  • Wolbachia did not extend longevity in all Drosophila genotypes, even though 16s rDNA sequences indicated that our Drosophila stocks were infected with the same Wolbachia strain. (semanticscholar.org)
  • For example, a virulent strain of Wolbachia has been shown to replicate inappropriately in the adult nervous system, causing paralysis and early death ( Min and Benzer, 1997 ). (biologists.org)
  • The pathogenic Wolbachia strain w MelPop is detected in the central nervous system, muscles, and retina of Drosophila melanogaster . (springer.com)
  • This study considers the influence of low (16°C) and high (29°C) temperature on the survival and lifespan of D. melanogaster females infected with the Wolbachia strain w MelPop. (springer.com)
  • Here, we carry out the first test as to whether a male-killing strain of Wolbachia also provides a direct benefit to its host by providing antiviral protection to its host Drosophila bifasciata . (biomedcentral.com)
  • In the first male-killing Wolbachia strain tested for antiviral effects, we found no evidence that it conferred protection against two RNA viruses. (biomedcentral.com)
  • Previously we reported the stable transinfection of the major dengue vector Aedes aegypti with a life-shortening Wolbachia strain (wMelPop-CLA) from the vinegar fly Drosophila melanogaster. (nih.gov)
  • In addition to influencing the invasion dynamics of this particular Wolbachia strain, we suggest that the negative impact of wMelPop-CLA on embryonic quiescence may have applied utility as a tool to reduce mosquito population size in regions with pronounced dry seasons or in regions that experience cool winters. (nih.gov)
  • The Wolbachia strain wMel did not affect the frequency of apoptosis in cells of the germarium. (biomedcentral.com)
  • The presence of the Wolbachia strain wMelPop in the D. melanogaster w1118 ovaries increased the number of germaria where cells underwent apoptosis in the checkpoint. (biomedcentral.com)
  • Our current study demonstrated that the Wolbachia strain wMelPop affects the egg chamber formation in the D. melanogaster ovaries. (biomedcentral.com)
  • There was no similar adverse effect in D. melanogaster Canton S infected with the Wolbachia strain wMel. (biomedcentral.com)
  • This was taken to mean that the observed increase in frequency of apoptosis was not the general effect of Wolbachia on germline cells of D. melanogaster , it was rather induced by the virulent Wolbachia strain wMelPop. (biomedcentral.com)
  • 8 What Defines a Strain of Wolbachia? (els.net)
  • We investigated methods of artificially inducing thelytoky by transferring thelytoky-inducing Wolbachia from wasps of the infected strain (the donor wasps) to wasps that had been cured of Wolbachia and to wasps of the uninfected strain (the recipient wasps). (springer.com)
  • When the researchers inoculated flies with spores from this fungus, Wolbachia -infected flies fared better than flies of the same strain that had been treated with tetracycline to cure them of their endosymbiont. (asmblog.org)
  • Finally, we demonstrate that the fidelity of asymmetric segregation to the self-renewing neuroblast is lower in the virulent Popcorn strain of Wolbachia . (biologists.org)
  • Popcorn (W Pop ), a virulent strain of Wolbachia , provides a particularly striking demonstration of the role of Wolbachia -specific factors as it over-replicates in adult neurons and muscle cells ultimately causing tissue degeneration and premature death ( Min and Benzer, 1997 ). (biologists.org)
  • A male-killing strain of Spiroplasma (strain Melanogaster Sex Ratio Organism (MSRO)) co-occurs with Wolbachia (strain wMel) in certain wild populations of the model organism Drosophila melanogaster. (unboundmedicine.com)
  • Now, O'Neill's team, together with Ary Hoffmann at the University of Melbourne, have infected A.aegypti mosquitoes with a strain of Wolbachia called wMel, which has spread through the world's fruit flies in the last 80 years. (discovermagazine.com)
  • Either way, here, at last, was a strain of Wolbachia that could turn Australia's mosquitoes into dead-ends for dengue. (discovermagazine.com)
  • Sinkins, Steven P., The Wolbachia strain wAu provides highly efficient virus transmission blocking in Aedes aegypti. (edu.au)
  • Wolbachia are maternally inherited bacterial endosymbionts that naturally infect a diverse array of arthropods. (lancs.ac.uk)
  • Wolbachia endosymbionts present a unique model for investigating the molecular underpinnings of host-symbiont interactions. (biologists.org)
  • Lateral gene transfer (LGT) from bacterial Wolbachia endosymbionts has been detected in ~20% of arthropod and nematode genome sequencing projects. (biomedcentral.com)
  • Wolbachia are maternally inherited bacterial endosymbionts that occupy many but not all tissues of adult insects. (biologists.org)
  • We focused on Wolbachia endosymbionts that are carried naturally in the germ cells of fruit flies. (prolekare.cz)
  • Though Wolbachia endosymbionts are naturally carried within germline cells of both male and female insects, Wolbachia are ultimately removed from sperm prior to completion of spermatogenesis [ 17 , 18 , 21 - 25 ]. (prolekare.cz)
  • Here we test for attenuation by selecting strains of Drosophila melanogaster infected with wMelPop for early and late reproduction in three independent outcrossed populations. (nih.gov)
  • successfully used f or the containment, suppression or ev en eradication of populations of insect pests. (deepdyve.com)
  • We discuss the potential mechanisms of this, and can seemingly discount protection against these viruses as a reason why this symbiont has spread through Drosophila populations. (biomedcentral.com)
  • In this work, we examined the ability of these primers to detect Wolbachia in Anastrepha populations from three regions in the State of São Paulo, southeastern Brazil. (scielo.br)
  • This might point to a positive fitness effects of the Wolbachia , which could help Wolbachia spread in populations," evolutionary geneticist Ary Hoffmann of The University of Melbourne, who was not involved in the research, wrote in an email to The Scientist . (the-scientist.com)
  • In bidirectional CI one of two different strains of Wolbachia are present in two populations of Drosophila . (els.net)
  • On the other hand, in natural populations of the closely-related D. melanogaster , the infecting Wolbachia doesn't interfere with host reproduction. (asmblog.org)
  • Since epizootics caused by pathogenic fungi are a major factor limiting insect populations in nature, a group of Russian researchers asked whether Wolbachia helped D. melanogaster stave off infections by a fungus. (asmblog.org)
  • We investigated the correlation between microsatellite- and pedigree-based coefficients of inbreeding and relatedness in laboratory populations of Drosophila melanogaster that had passed through bottlenecks to manipulate their genetic diversity. (wiley.com)
  • The Wolbachia Genome Consortium. (semanticscholar.org)
  • Our work provides comprehensive insight into the developmental dynamics of gene expression for a widespread endosymbiont in its natural host context, and shows that public gene expression data harbor rich resources to probe the functional basis of the Wolbachia-Drosophila symbiosis and annotate the transcriptional outputs of the Wolbachia genome. (g3journal.org)
  • While we do not disagree with the first conclusion, the authors base their second conclusion on the lack of homology detected between their improved CAF1 genome assembly attributed to D. ananassae and reference Wolbachia genomes. (g3journal.org)
  • While the consensus CAF1 genome assembly lacks any sequence similarity to the reference genome of the Wolbachia endosymbiont of Drosophila melanogaster ( w Mel), numerous studies from multiple laboratories provide experimental support for a large lateral/horizontal gene transfer (LGT) of a Wolbachia genome into this D. ananassae line. (g3journal.org)
  • As such, we strongly suspect that the original whole genome assembly was either constructed after the removal of all Wolbachia reads, or that Wolbachia sequences were directly removed from the contigs in the CAF1 assembly. (g3journal.org)
  • Although we do not disagree with the first conclusion, we were surprised to see that the authors stated that the Wolbachia sequences integrated into the D. ananassae genome are a minor contributor to expansion of the Muller F Element. (g3journal.org)
  • The authors base their conclusions on the lack of homology detected between their improvements to the CAF1 genome assembly attributed to D. ananassae and reference Wolbachia genomes. (g3journal.org)
  • In particular, the sequencing center responsible for two of the Drosophila genome projects (Agencourt Biosciences) mistakenly deposited 20,000 sequences from D. ananassae and labeled them as D. mojavensis . (biomedcentral.com)
  • Many of these transfers are large and contain a substantial part of the Wolbachia genome. (biomedcentral.com)
  • We find that multiple copies of the Wolbachia genome are transferred to the Drosophila nuclear genome in all three lines. (biomedcentral.com)
  • In the D. ananassae line from Indonesia, the copies of Wolbachia DNA in the nuclear genome are nearly identical in size and sequence yielding an even coverage of mapped reads over the Wolbachia genome. (biomedcentral.com)
  • In contrast, the D. ananassae lines from Hawaii and India show an uneven coverage of mapped reads over the Wolbachia genome suggesting that different parts of these LGTs are present in different copy numbers. (biomedcentral.com)
  • 2004) Phylogeneomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements. (els.net)
  • The genome of D. innubila was sequenced for a study in 2019, and boasts a very complete assembly rivalling that of the classic genetic model Drosophila melanogaster. (wikipedia.org)
  • As long as the host remains colonized by its Wolbachia endosymbiont, LGT can continue and Wolbachia DNA can accumulate in the Drosophila genome. (the-scientist.com)
  • Just how Wolbachia DNA inserts itself into the Drosophila genome is unclear. (the-scientist.com)
  • Three likely mechanisms include nonhomologous repair of a double-strand break (A), insertion of a fly retrotransposon into the Wolbachia genome followed by homologous recombination with another copy of the retrotransposon in the fly genome (B), and/or homologous recombination with a prior nuclear Wolbachia transfer (nuwt) (C). (the-scientist.com)
  • see for example how segment polarity in drosophila is controlled by neighboring cells, or how the gender of alligators is controlled by external temperature, or how plants exchange genetic material, or how aprox 8% human genome is comprised of retroviral DNA , the influence of gut microbiota of host phenotypes (e.g. (scholarpedia.org)
  • The dAPC2 start site was determined by the coincidence of the five longest Berkeley Drosophila Genome Project cDNAs and our 5′ rapid amplification of cDNA ends (RACE) cDNA products. (rupress.org)
  • Nucleosome organization in the Drosophila genome. (wadsworth.org)
  • What would be the prediction for the complete Wolbachia genome in Drosophila ananassae ? (blogspot.com)
  • However, evolutionary changes in the host and Wolbachia genomes might attenuate any life span effects mediated by wMelPop. (nih.gov)
  • In the process of generating these data we received several inquiries about the status of this project so, in the spirit of Open Science that makes genomics such a productive field, we have released the consensus sequences and alignments of 179 Wolbachia and 290 mitochondrial genomes from the DGRP and DPGP prior to publication of our manuscript. (uga.edu)
  • Evidence for a Wolbachia symbiont in Drosophila melanogaster. (nih.gov)
  • Here we use RNA-seq to study the impact of Wolbachia on D. paulistorum and investigate the hypothesis that the symbiont may play a role in host speciation. (biomedcentral.com)
  • The 16s rDNA sequence is over 98% identical to Wolbachia known from other insects. (pnas.org)
  • Wolbachia , a genus of the Rickettsial family, although not yet reported in mammals, is widespread among insects. (pnas.org)
  • Wolbachia , a maternally transmitted endosymbiont of insects, is increasingly being seen as an effective biological control agent that can interfere with transmission of pathogens, including dengue virus. (asm.org)
  • The most promising of these efforts employs Wolbachia , a maternally transmitted endosymbiotic bacterium naturally found in 40% of insects. (mdpi.com)
  • Wolbachia can spread through a population of insects while simultaneously inhibiting the replication of viruses within its host. (mdpi.com)
  • Between 20% and 60% of Neotropical insects are infected with Wolbachia (28). (scielo.br)
  • Wolbachia is a maternally transmitted endosymbiotic bacterium widespread in insects. (frontiersin.org)
  • In some insects, Wolbachia kills males and converts developing males to females. (newscientist.com)
  • The potential of virulent Wolbachia to modulate disease transmission by insects. (ajtmh.org)
  • We examined the effects of Spiroplasma MSRO and Wolbachia wMel on Drosophila survival against parasitism by two common wasps, Leptopilina heterotoma and Leptopilina boulardi, that differ in their host ranges and host evasion strategies. (unboundmedicine.com)
  • The symbiosis between Wolbachia and Drosophila is an excellent system to experimentally address these issues. (prolekare.cz)
  • in mosquitoes, Wolbachia can interfere with accumulation and transmission of important human pathogens, including dengue and Chikungunya viruses ( 7 - 17 ). (asm.org)
  • In mosquitoes, Wolbachia interferes with viral replication/accumulation, while in Drosophila , Wolbachia can interfere with viral replication/accumulation and/or protect flies from virus-induced mortality. (asm.org)
  • The density and distribution of Wolbachia in host tissues have been implicated as contributing factors by previous studies with both mosquitoes and flies. (asm.org)
  • Despite successes in using Wolbachia -transfected mosquitoes to limit dengue, Zika, and chikungunya transmission, the mechanisms behind pathogen-blocking have not been fully characterized. (mdpi.com)
  • This discovery pointed to a potential strategy to interfere with mosquito transmission of arboviruses by artificially infecting mosquitoes with Wolbachia. (mdpi.com)
  • The findings could have implications for the use of Wolbachia to control vector-borne diseases, an effort that has shown recent promise to limit the transmission of malaria and dengue transmission via mosquitoes, for example. (the-scientist.com)
  • Can Wolbachia modulate the fecundity costs of Plasmodium in mosquitoes? (cambridge.org)
  • Although Wolbachia- infected mosquitoes fare overall better than uninfected ones, Wolbachia does not confer a sufficiently high reproductive boost to mosquitoes to compensate for the reproductive losses inflicted by Plasmodium. (cambridge.org)
  • by screening field-collected adult mosquitoes using two Wolbachia -specific molecular makers. (biomedcentral.com)
  • adult mosquitoes using Wolbachia -specific 16S rDNA and its surface protein ( wsp ). (biomedcentral.com)
  • The National Environment Agency of Singapore released Wolbachia infected male mosquitoes last April in order to suppress the local population. (edu.au)
  • By May, the proportion of Wolbachia -infected mosquitoes had risen from nothing to 80 percent in Gordonvale and over 90 percent in Yorkeys Knob. (discovermagazine.com)
  • For the past five to seven years, our food chain has been infected via Wolbachia-infected Aedes male mosquito releases. (infobarrel.com)
  • Deploying dengue-suppressing Wolbachia : Robust models predict slow but effective spatial spread in Aedes aegypti. (escholarship.org)
  • Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti. (escholarship.org)
  • A new approach for dengue control has been proposed that relies on life-shortening strains of the obligate intracellular bacterium Wolbachia pipientis to modify mosquito population age structure and reduce pathogen transmission. (nih.gov)
  • While Plasmodium is known to frequently express its virulence by partially castrating its mosquito vectors, the effects of Wolbachia infections on mosquito fecundity are, in contrast, highly variable. (cambridge.org)
  • Totals of 113 (16.8%) and 89 (13.2%) individual mosquito samples were determined to be infected with Wolbachia using the wsp and 16S rDNA markers, respectively. (biomedcentral.com)
  • sample sequences were similar or identical to five known Wolbachia strains belonging to supergroups A and B while the majority of 16S rDNA sample sequences were similar to strains belonging to supergroup B. Overall, 80 (11.90%) individual mosquito samples showed positive amplifications in both markers and 69% showed congruence in supergroup identification (supergroup B). (biomedcentral.com)
  • O xénero identificouse por primeira vez en 1924 por Marshall Hertig e Simeon Burt Wolbach no mosquito Culex pipiens . (wikipedia.org)
  • At first, he thought he could get Wolbachia to carry an antibody against dengue virus, and spread it through a mosquito population. (discovermagazine.com)
  • Wolbachia doesn't spread from mosquito to mosquito. (discovermagazine.com)
  • improved contigs attributed to the Muller F element from the original CAF1 assembly, and used them to conclude that most of the sequence expansion of the fourth chromosome of D. ananassae is due to a higher transposon load than previously thought, but is not due to Wolbachia DNA integrations. (g3journal.org)
  • highlights that an assembly of the Wolbachia sequence reads and their mate pairs was erroneously attributed solely to the Wolbachia endosymbiont, albeit before we understood the extent of LGT in D. ananassae . (g3journal.org)
  • As such, we recommend that the sequences deposited at the National Center for Biotechnology Information (NCBI) under PRJNA13365 should not be attributed to Wolbachia endosymbiont of D. ananassae , but should have their taxonomy reclassified by NCBI as "Unclassified sequences. (g3journal.org)
  • as well as improvements they made, to conclude that most of the sequence expansion of the fourth chromosome of D. ananassae is due to a higher transposon load than previously thought, but is not due to Wolbachia DNA integrations. (g3journal.org)
  • Drosophila flies infected with five diverse strains of Wolbachia were screened for the ability to mediate antiviral protection. (asm.org)
  • The three protective Wolbachia strains were more closely related and occurred at a higher density within whole flies than the two nonprotective Wolbachia strains. (asm.org)
  • Although wild type flies of each semispecies are isolated from the others by both pre- and postmating incompatibilities, mating between semispecies and successful offspring development can be achieved once flies are treated with antibiotics to reduce Wolbachia titer. (biomedcentral.com)
  • Both viruses caused considerable mortality to D. bifasciata flies, with Drosophila C virus killing 43% more flies than the uninfected controls and Flock House virus killing 78% more flies than the uninfected controls. (biomedcentral.com)
  • The fts Z primer was the first primer used to detect Wolbachia in Anastrepha fruit flies. (scielo.br)
  • Studies in different regions of Brazil have detected Wolbachia in fruit flies of the genus Anastrepha (3, 4, 17, 23). (scielo.br)
  • Wolbachia -infected flies laid 3.5 to 4 times more eggs than uninfected individuals. (the-scientist.com)
  • A closer look at the activity of the cells within the niche revealed that the stem cells of Wolbachia -infected flies were dividing at a faster rate than their uninfected counterparts-about twice as quickly. (the-scientist.com)
  • Following the stem cells that divided and differentiated into egg cell precursors, the researchers found the answer: Compared with uninfected flies, the cells of Wolbachia -infested flies underwent only about half the amount of programmed cell death, a normal regulatory process of egg development. (the-scientist.com)
  • Based on the appearance in the electron microscope, there was no difference in morphological features of apoptotic cystocytes between Wolbachia -infected and uninfected flies. (biomedcentral.com)
  • Recently, two research labs (click here and here ) independently reported that if the adult flies are infected with Wolbachia before being challenged with the virus, they survive longer. (asmblog.org)
  • Following up on the serendipitous discovery, her team found that flies not infected with Wolbachia lasted less than a week when exposed to a Drosophila virus, while flies carrying Wolbachia lived up to two weeks. (newscientist.com)
  • For two other insect viruses, the difference was even starker, with Wolbachia -infected flies lasting weeks longer. (newscientist.com)
  • An ARC Discovery Project integrating aspects of nutrition, parasitism and gut microbiome on immunity in Drosophila flies in collaboration with Prof Steve Simpson and Dr Fleur Ponton at the University of Sydney, Australia. (lancaster.ac.uk)
  • Wolbachia also confers a weak, but significant, survival advantage to flies attacked by L. heterotoma. (unboundmedicine.com)
  • Since that discovery, Wolbachia -mediated antiviral effects have been demonstrated in a number of insect hosts and are being investigated as a way of limiting spread of arboviruses (reviewed in references 1 , 4 , 5 , and 6 ). (asm.org)
  • Wolbachia are transmitted from female hosts to their offspring, in a manner that is analogous to mitochondrial inheritance. (biologists.org)
  • Wolbachia have been found to participate in a range of biological interactions with arthropod hosts, from nutritional mutualism and protection against pathogens to various forms of reproductive parasitism [ 19 , 20 ]. (biomedcentral.com)
  • Wolbachia have high prevalence among arthropods, but they are often facultative for these hosts. (biomedcentral.com)
  • Wolbachia sequences used in this analysis were from infections in coleopteran ( Diabrotica ), dipteran ( Drosophila ), hymenopteran ( Muscidifurax ) and filarial worm ( Brugia ) hosts. (els.net)
  • If this were the only factor, the percentage of Wolbachia -infected hosts would decrease with each generation. (asmblog.org)
  • You may be acquainted with one of these factors-the strategies some Wolbachia use to manipulate the reproduction of their hosts and thereby increase the number of infected individuals. (asmblog.org)
  • That 2.5% may sound small, but it causes the percentage of Wolbachia -infected hosts to decline generation after generation. (asmblog.org)
  • Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. (cambridge.org)
  • We discuss the implications of these Wolbachia strains for the evolution and diversification of their dung beetle hosts in Madagascar. (frontiersin.org)
  • Members of the genus Spiroplasma associated with distantly related Drosophila hosts are known to engage in either reproductive parasitism (i.e., male killing) or defense against natural enemies (the parasitic wasp Leptopilina heterotoma and a nematode). (unboundmedicine.com)
  • Occurrence of Spiroplasma-mediated protection against distinct parasitoids in divergent Drosophila hosts suggests a general protection mechanism. (unboundmedicine.com)
  • Wolbachia is transmitted in the eggs of infected females, so it has evolved many strategies for reaching new hosts by screwing over dead-end males. (discovermagazine.com)
  • In: Ashburner M, Novitski E (eds) The genetics and biology of Drosophila . (springer.com)
  • This tropism is pervasive across the Drosophila genus, with the pattern of targeting being evolutionarily conserved. (bu.edu)
  • We then searched through the newly updated D. mojavensis sequences for the 114 Wolbachia sequences that we had originally reported, and found that all had been removed. (biomedcentral.com)
  • Fifteen new Wolbachia 16S rDNA sequences were detected. (scielo.br)
  • Therefore, the relationship between Wolbachia and host is generally regarded as symbiotic. (pnas.org)
  • The bacterial cell division gene, ftsZ, was used as a specific probe to show the presence of a symbiotic bacterium in two wild type strains of Drosophila melanogaster. (nih.gov)
  • On the Dec. 6th TWiV podcast , Vincent Racaniello and Dickson Despommier discuss the symbiotic bacterium Wolbachia, the origin of the 2009 influenza H1N1 virus, and 'the lure of original antigenic sin. (plos.org)
  • A) Schematic representation of Drosophila melanogaster ovaries, stages of oogenesis (germarium [g] and stages S2 to S14), and enlarged view of S10 egg chamber. (asm.org)
  • Our investigation indicates that gurken ( grk ), a host gene encoding a crucial axis determinant, has a cumulative, dosage-sensitive impact on Wolbachia growth and proliferation during Drosophila oogenesis. (biologists.org)
  • Wolbachia have the advantage that they can be studied in a well-established model system, Drosophila oogenesis. (biologists.org)
  • In addition, we identify mid-oogenesis as a period in the life cycle of Wolbachia in which bacterial replication occurs. (princeton.edu)
  • The pathways along which Wolbachia influences Drosophila oogenesis have been, so far, little studied. (biomedcentral.com)
  • In addition to its functional importance in Wolbachia transmission, the well-characterized molecular and cell biology of Drosophila oogenesis has provided considerable contextual information and experimental tools that can be applied to studies of Wolbachia -host interactions [ 18 , 26 - 30 ]. (prolekare.cz)
  • A host-parasite interaction suppresses oogenesis defects of Drosophila sex-determination gene mutants. (berkeley.edu)
  • 15 ). Drosophila mitochondrial gene primers were used for a positive control of the reaction. (pnas.org)
  • For example, primers for 16S rDNA (a ribosomal gene), fts Z (a regulatory gene of the bacterial cell cycle) and wsp (a gene for an cell membrane protein) have been used to study the phylogenetics of Wolbachia (2, 6, 18) and have led to the division of Wolbachia into eight taxonomic supergroups (A to H) (12, 13, 27). (scielo.br)
  • The ftsZ gene was extensively used by Werren and colleagues (27, 28) to detect Wolbachia , but several studies have demonstrated its low sensitivity (3, 9, 30, 31). (scielo.br)
  • Bownes M, Scott A, Shirras A (1988) Dietary components modulate yolk protein gene transcription in Drosophila melanogaster . (springer.com)
  • One of the most well-studied examples of lateral gene transfer (LGT) between microbe and animal is the transfer of DNA from an intracellular Wolbachia endosymbiont to its Drosophila host. (the-scientist.com)
  • Drosophila switch gene Sex-lethal can bypass its switch-gene target transformer to regulate aspects of female behavior. (berkeley.edu)
  • Evolution of the Drosophila feminizing switch gene Sex-lethal . (berkeley.edu)
  • Sexual back talk with evolutionary implications: stimulation of the Drosophila sex-determination gene Sex-lethal by its target transformer . (berkeley.edu)
  • Recruitment of the proneural gene scute to the Drosophila sex-determination pathway. (berkeley.edu)
  • Functioning of the Drosophila integral U1/U2 protein independent of U1 and U2 small nuclear ribonucleoprotein particles is revealed by snf + gene dose effects. (berkeley.edu)
  • In this study dynamin (encoded by the shibire gene) is shown to enhance activity-evoked peptide release at the Drosophila neuromuscular junction . (sdbonline.org)
  • They are primarily known for their manipulation of host reproductive biology, and recently, infections with Wolbachia have been proposed as a new strategy for controlling insect vectors and subsequent human-transmissible diseases. (lancs.ac.uk)
  • Even though Wolbachia infections are the largest pandemic on this planet, the cellular and molecular mechanisms for bacterial spreading in nature are still unknown. (bu.edu)
  • So, this suggests that this Wolbachia benefits its host by protecting it against RNA virus infections. (asmblog.org)
  • Widespread prevalence of wolbachia in laboratory stocks and the implications for Drosophila research. (semanticscholar.org)
  • 2008). Accurate estimates of Wolbachia prevalence are difficult to obtain, and both under and/or overestimation may occur. (scielo.br)
  • The various qualitative and quantitative effects seen in different Wolbachia -host combinations pose the question of what bacterium-host interactions are at play. (pnas.org)
  • Our results show fundamental interactions between diet composition, host diet selection, Wolbachia abundance and effects on host lifespan and fecundity. (lancs.ac.uk)
  • Wolbachia interactions that determine Drosophila melanogaster survival. (semanticscholar.org)
  • Unraveling the cellular and molecular bases of tissue tropism is fundamental to understanding Wolbachia-host interactions. (bu.edu)
  • Comparisons between mushroom-feeding Drosophila and D. melanogaster, and also between mushroom-specific Howardula parasitic nematodes and generalist nematodes could yield insight into how host-pathogen interactions alter olfactory preferences. (wikipedia.org)
  • While in many cases Wolbachia confers antiviral effects to its host organism, in some cases the presence of Wolbachia can enhance viral susceptibility ( 18 - 23 ). (asm.org)
  • Wolbachia endosymbiosis has been well characterized within the model organism Drosophila , in which protection against viral challenge has been observed ( 15 , 36 , 39 ). (asm.org)
  • In some Wolbachia -host combinations, a delay in the accumulation of viral particles was observed concurrently with a delay in mortality ( 15 , 36 , 39 ). (asm.org)
  • However, viral induced mortality was unaffected by the presence of Wolbachia . (biomedcentral.com)
  • As infeccións por Wolbachia foron asociadas coa resistencia viral na mosca Drosophila melanogaster e en especies de mosquitos. (wikipedia.org)
  • Wolbachia genes change the viral response of drosophila), etc. (scholarpedia.org)
  • Studies in the major genetic model organism Drosophila melanogaster are how the Wnt signalling pathway was first suspected. (wikipedia.org)
  • We show that although antiviral resistance is widespread across the Wolbachia phylogeny, the trait seems to have been lost or gained along some lineages. (biomedcentral.com)
  • Wolbachia -specific 16s rDNA primers were according to O'Neill et al . (pnas.org)
  • The primers for 16S rDNA, fts Z and wsp and the corresponding PCR conditions have been optimized to study the distribution of Wolbachia and their effect on the biology of Anastrepha in Brazil. (scielo.br)
  • These findings indicate that reliable PCR detection of Wolbachia requires the use of primers for 16S rDNA and wsp to avoid cross-reactions and false negatives, and that the fts Z primer needs to be redesigned to improve its selectivity. (scielo.br)
  • Phylogeny of Wolbachia and related groups derived from 1.3 kb of 16S rDNA sequence. (els.net)
  • Each individual sample was processed and screened for the presence of Wolbachia by selected markers, Wolbachia -specific 16S rDNA and its surface protein ( wsp ), under optimized PCR conditions and sequenced. (biomedcentral.com)
  • Sex-biased genes are often organized as small operons of uncharacterized genes and are mainly up-regulated in adult Drosophila males in an age-dependent manner. (g3journal.org)
  • If niche tropism is important for Wolbachia transmission through the germline, evolutionary theory predicts that there should be no selective pressure to maintain niche tropism in males. (bu.edu)
  • In Australian Eurema hecabe butterflies Wolbachia feminises genetic males and convert them into functional females (collaboration with Darrell Kemp at Macquarie University). (exeter.ac.uk)
  • In these conditions, Wolbachia can obscure studies of mitochondrial variation in the host population. (frontiersin.org)
  • The patterning of Drosophila wings has long been of interest to evolutionary biologists as understanding the genetic changes underlying wing patterning helps understand how evolution can act to promote novel designs. (wikipedia.org)
  • Wolbachia is a naturally occurring endosymbiont which can be maternally inherited and cause different reproductive alterations in its host to increase their transmission to the next generation [ 1 , 2 , 3 ]. (biomedcentral.com)
  • The mechanisms involved in Wolbachia -mediated antiviral effects have not yet been fully elucidated. (asm.org)
  • Image of several progressively more differentiated egg chambers (oldest at bottom) in Drosophila mauritiana. (the-scientist.com)
  • Wolbachia can infiltrate germline stem cells of the fruit fly Drosophila mauritiana , where it spurs increased cell division of gamete precursors and lower rates of cell death, according to a study published today (October 20) in Science Express . (the-scientist.com)
  • In the new study, cell biologist Horacio Frydman of Boston University and his colleagues showed Wolbachia can increase the number of eggs produced by D. mauritiana females. (the-scientist.com)
  • Image of a succession of progressively more differentiated egg chambers in Drosophila mauritiana, originating from the germarium (top). (the-scientist.com)
  • My guess is that when researchers start to look in more detail in other systems, they're going to find that Wolbachia are routinely manipulating stem cell biology. (the-scientist.com)
  • In summary, our results implicate that Wolbachia might be a frequent factor in host speciation, but usually only by contributing to overall reproductive isolation among other factors. (hu-berlin.de)
  • We have found that Wolbachia target the stem cell niches in the Drosophila ovary to enhance germline colonization and subsequent vertical transmission. (bu.edu)
  • The primary developmental units of the ovary that carry Wolbachia are referred to as egg chambers [ 27 , 28 ]. (prolekare.cz)
  • The Neotropical fruit fly Drosophila paulistorum (Diptera: Drosophilidae) is considered a classical example of incipient speciation. (biomedcentral.com)
  • Steiner, Florian M, Life-history traits and physiological limits of the alpine fly Drosophila nigrosparsa (Diptera: Drosophilidae): A comparative study. (edu.au)
  • Perhaps Wolbachia primes the mosquito's immune system to fight off other invaders, such as dengue virus. (discovermagazine.com)
  • It is therefore essential to better understand the factors that modulate Wolbachia abundance and effects on host fitness. (lancs.ac.uk)
  • The endosymbiotic bacterium Wolbachia spp. (asm.org)
  • O'Neill also found that Wolbachia had started to spread beyond the two suburbs into surrounding neighbourhoods. (discovermagazine.com)
  • This study indicates that Wolbachia -mediated protection may vary between larval and adult stages of a given Wolbachia -host combination and that the variations in susceptibility by life stage correspond with Wolbachia density. (asm.org)
  • In this paper, we focus on the effect of Wolbachia on the survival of the host, and we define protection as a reduction/delay in virus-induced mortality. (asm.org)
  • These findings may facilitate the development of Wolbachia biological control strategies and help to predict host- Wolbachia pairings that may interfere with virus-induced pathology. (asm.org)
  • This effect appears to be mediated by grk mRNA and its protein-binding partners Squid and Hrp48/Hrb27C, implicating the grk mRNA-protein (mRNP) complex as a rate-limiting host factor controlling Wolbachia titer. (biologists.org)
  • Wolbachia utilizes host microtubules and Dynein for anterior localization in the Drosophila oocyte. (princeton.edu)
  • These findings demonstrate that Wolbachia utilize the host microtubule network and associated proteins for their subcellular localization in the Drosophila oocyte. (princeton.edu)
  • Wolbachia -host LGT events are termed nuwts [ 6 ] for nu clear W olbachia t ransfers (pronounced: noot) following the established nomenclature for numts and nupts, nu clear p lastid t ransfers. (biomedcentral.com)
  • And a growing number of studies report that Wolbachia directly interferes with viruses and other pathogens inside the arthropod host. (infobarrel.com)
  • The red lines indicate representative Wolbachia lineages that have specialized in manipulating host reproduction. (els.net)
  • Wolbachia host genera are shown in parentheses. (els.net)
  • Crossed lines indicate two key biological differences: (1) Wolbachia have lost the ability to infect mammals and (2) have acquired the ability to alter host reproduction. (els.net)
  • Such observations suggest that this Wolbachia must be conferring some fitness on its host. (asmblog.org)
  • This centrosome association is microtubule-dependent and promotes an even Wolbachia distribution throughout the host embryo. (biologists.org)
  • Insights into mechanisms of Wolbachia segregation during host mitosis have come from studying initial mitotic divisions in early Drosophila embryogenesis. (biologists.org)
  • Effects of tetracycline and rifampicin treatments on the fecundity of the Wolbachia-infected host, Tribolium confusum (Coleoptera: Tenebrionidae) , 109(3), 1458-1464. (gc.ca)
  • 2. CI-inducing Wolbachia has the potential to affect the population dynamics of their host via reduced offspring production. (exeter.ac.uk)
  • The host protective effects exhibited by Spiroplasma and Wolbachia are additive and may provide the conditions for such cotransmitted symbionts to become mutualists. (unboundmedicine.com)
  • We found that the majority of Wolbachia genes are expressed stably across the D. melanogaster life cycle, but that 7.8% of Wolbachia genes exhibit robust stage- or sex-specific expression differences when studied in the whole-organism context. (g3journal.org)
  • Differentially-expressed Wolbachia genes are typically up-regulated after Drosophila embryogenesis and include many bacterial membrane, secretion system, and ankyrin repeat-containing proteins. (g3journal.org)
  • We also speculate that the observed differential expression of genes associated with chemical communication and reproduction may be associated with the emergence of pre- and postmating barriers between semispecies, which supports a role for Wolbachia in the speciation of D. paulistorum . (biomedcentral.com)
  • Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes. (berkeley.edu)
  • Wolbachia (stained in green) are highly concentrated in the GSCN, at the tip of the germarium. (the-scientist.com)
  • It is known that Wolbachia are abundant in the somatic stem cell niche of the Drosophila germarium. (biomedcentral.com)
  • Here we address the question whether or not the presence of Wolbachia in germarium cells can affect the frequency of cyst apoptosis in the checkpoint. (biomedcentral.com)
  • The Drosophila Wnt signalling pathway regulates wing development. (wikipedia.org)
  • An extracellular activator of the Drosophila JAK/STAT pathway is a sex-determination signal element. (berkeley.edu)
  • H uman β-catenin (βcat) 1 and its Drosophila homologue Armadillo (Arm) are key effectors of the conserved Wingless (Wg)/Wnt signal transduction pathway (for review see Gumbiner 1998 ). (rupress.org)
  • Windpipe Controls Drosophila Intestinal Homeostasis by Regulating JAK/STAT Pathway via Promoting Receptor Endocytosis and Lysosomal Degradation. (stembook.org)
  • Electron microscopy and confocal imaging techniques demonstrated a substantial accumulation of Wolbachia in the germline stem cell niche (GSCN), where the stem cells that form the females' eggs are stored. (the-scientist.com)