Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
Infestation with parasitic worms of the helminth class.
Infestation of animals with parasitic worms of the helminth class. The infestation may be experimental or veterinary.
The treatment of immune system diseases by deliberate infestation with helminths. This therapy is partly based on the HYGIENE HYPOTHESIS which states that the absence of parasites increases immune dysregulation because of the lack of stimulation of REGULATORY T-CELLS.
Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
A genus of nematode worms comprising the whipworms.
Immunoglobulins produced in a response to HELMINTH ANTIGENS.
Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.
A superfamily of nematode parasitic hookworms consisting of four genera: ANCYLOSTOMA; NECATOR; Bunostomum; and Uncinaria. ANCYLOSTOMA and NECATOR occur in humans and other mammals. Bunostomum is common in ruminants and Uncinaria in wolves, foxes, and dogs.
Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
Proteins found in any species of helminth.
A species of intestinal nematode parasites which occur most commonly in mice. Infection is by ingesting larvae. This particular species is used extensively in immunological research.
Infections with nematodes of the order STRONGYLIDA.
Infections by nematodes, general or unspecified.
A subclass of segmented worms comprising the tapeworms.
Determination of parasite eggs in feces.
A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
A species of trematode blood flukes of the family Schistosomatidae. It is common in the Nile delta. The intermediate host is the planorbid snail. This parasite causes schistosomiasis mansoni and intestinal bilharziasis.
Infections with unicellular organisms formerly members of the subkingdom Protozoa.
A superfamily of nematodes of the suborder SPIRURINA. Its organisms possess a filiform body and a mouth surrounded by papillae.
A genus of trematode flukes belonging to the family Schistosomatidae. There are over a dozen species. These parasites are found in man and other mammals. Snails are the intermediate hosts.
Infections with true tapeworms of the helminth subclass CESTODA.
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
A genus of intestinal nematode parasites belonging to the superfamily HELIGMOSOMATOIDEA, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits. Infection is usually through the skin.
Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.
Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.
Class of parasitic flukes consisting of three subclasses, Monogenea, Aspidogastrea, and Digenea. The digenetic trematodes are the only ones found in man. They are endoparasites and require two hosts to complete their life cycle.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Deoxyribonucleic acid that makes up the genetic material of helminths.
A species of helminth commonly called the sheep liver fluke. It occurs in the biliary passages, liver, and gallbladder during various stages of development. Snails and aquatic vegetation are the intermediate hosts. Occasionally seen in man, it is most common in sheep and cattle.
Infections caused by infestation with worms of the class Trematoda.
A common parasite of humans in the moist tropics and subtropics. These organisms attach to villi in the small intestine and suck blood causing diarrhea, anorexia, and anemia.
The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
The unconsolidated mineral or organic matter on the surface of the earth that serves as a natural medium for the growth of land plants.
A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
Infections or infestations with parasitic organisms. They are often contracted through contact with an intermediate vector, but may occur as the result of direct exposure.
Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
A parasite of carnivorous mammals that causes TRICHINELLOSIS. It is especially common in rats and in swine fed uncooked garbage. Human infection is initiated by the consumption of raw or insufficiently cooked pork or other meat containing the encysted larvae.
A species of parasitic nematode widely distributed in tropical and subtropical countries. The females and their larvae inhabit the mucosa of the intestinal tract, where they cause ulceration and diarrhea.
Infection with tapeworms of the genus Hymenolepis.
The study of parasites and PARASITIC DISEASES.
A genus of large tapeworms.
Infection of humans or animals with hookworms of the genus NECATOR. The resulting anemia from this condition is less severe than that from ANCYLOSTOMIASIS.
A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.
A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
A superfamily of strongyles or roundworms which are parasites in the intestinal tract of equines, pigs, rodents, and primates (including man). It includes the genera Cyasthostomum, Ransomus, Globocephalus, OESOPHAGOSTOMUM, and STRONGYLUS.
The genetic complement of a helminth (HELMINTHS) as represented in its DNA.
Infection with nematodes of the genus STRONGYLOIDES. The presence of larvae may produce pneumonitis and the presence of adult worms in the intestine could lead to moderate to severe diarrhea.
The smallest species of TAPEWORMS. It is the only cestode that parasitizes humans without requiring an intermediate host.
Drugs used to treat or prevent parasitic infections.
An infection with TRICHINELLA. It is caused by eating raw or undercooked meat that is infected with larvae of nematode worms TRICHINELLA genus. All members of the TRICHINELLA genus can infect human in addition to TRICHINELLA SPIRALIS, the traditional etiological agent. It is distributed throughout much of the world and is re-emerging in some parts as a public health hazard and a food safety problem.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
A genus of nematode intestinal parasites that consists of several species. A. duodenale is the common hookworm in humans. A. braziliense, A. ceylonicum, and A. caninum occur primarily in cats and dogs, but all have been known to occur in humans.
Invertebrate organisms that live on or in another organism (the host), and benefit at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
An anthelmintic used in most schistosome and many cestode infestations.
A species of parasitic nematode usually found in domestic pigs and a few other animals. Human infection can also occur, presumably as result of handling pig manure, and can lead to intestinal obstruction.
Simultaneous infection of a host organism by two or more pathogens. In virology, coinfection commonly refers to simultaneous infection of a single cell by two or more different viruses.
A genus of small tapeworms of birds and mammals.
Infection with tapeworms of the genus Taenia.
Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
A superfamily of parasitic nematodes which requires one or two intermediate arthropod hosts before finally being eaten by the final host. Its organisms occur rarely in man.
An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).
A republic in western Africa, south of MALI and BURKINA FASO, bordered by GHANA on the east. Its administrative capital is Abidjan and Yamoussoukro has been the official capital since 1983. The country was formerly called Ivory Coast.
Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.
A species of trematode blood flukes of the family Schistosomatidae which occurs at different stages in development in veins of the pulmonary and hepatic system and finally the bladder lumen. This parasite causes urinary schistosomiasis.
Infection by flukes of the genus Echinostoma.
Infection by round worms of the genus TOXOCARA, usually found in wild and domesticated cats and dogs and foxes, except for the larvae, which may produce visceral and ocular larva migrans in man.
Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.
A white threadlike worm which causes elephantiasis, lymphangitis, and chyluria by interfering with the lymphatic circulation. The microfilaria are found in the circulating blood and are carried by mosquitoes.
A genus of parasitic nematodes widely distributed as intestinal parasites of mammals.
Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.
Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
A supergroup (some say phylum) of ameboid EUKARYOTES, comprising ARCHAMOEBAE; LOBOSEA; and MYCETOZOA.
A human disease caused by the infection of parasitic worms SCHISTOSOMA HAEMATOBIUM. It is endemic in AFRICA and parts of the MIDDLE EAST. Tissue damages most often occur in the URINARY TRACT, specifically the URINARY BLADDER.
Diseases that are underfunded and have low name recognition but are major burdens in less developed countries. The World Health Organization has designated six tropical infectious diseases as being neglected in industrialized countries that are endemic in many developing countries (HELMINTHIASIS; LEPROSY; LYMPHATIC FILARIASIS; ONCHOCERCIASIS; SCHISTOSOMIASIS; and TRACHOMA).
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
The science dealing with the establishment and maintenance of health in the individual and the group. It includes the conditions and practices conducive to health. (Webster, 3d ed)
The branch of medicine concerned with diseases, mainly of parasitic origin, common in tropical and subtropical regions.
An order of nematodes of the subclass SECERNENTEA. Its organisms are characterized by a single, ventral excretory gland and a relatively stout, short body.
A tri-benzene-ammonium usually compounded with zinc chloride. It is used as a biological stain and for the dyeing and printing of textiles.
Infection of humans or animals with hookworms of the genus ANCYLOSTOMA. Characteristics include anemia, dyspepsia, eosinophilia, and abdominal swelling.
Science dealing with the properties, distribution, and circulation of water on and below the earth's surface, and atmosphere.
A genus of parasitic nematodes whose organisms are distributed in Central and South America. Characteristics include a smooth cuticle and an enlarged anterior end.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
Parasitic infestation of the human lymphatic system by WUCHERERIA BANCROFTI or BRUGIA MALAYI. It is also called lymphatic filariasis.
A phylum of acoelomate, bilaterally symmetrical flatworms, without a definite anus. It includes three classes: Cestoda, Turbellaria, and Trematoda.
A superfamily of parasitic nematodes consisting of several genera. ENTEROBIUS, which occurs in humans, and Oxyuris, which occurs in horses, are two of the most common. Other genera are: Skrjabinema, Passalurus, Dermatoxys, and Probstmayria.
A species of tapeworm (TAPEWORMS) infecting RATS and MICE but rarely causing disease in humans. Its life cycle involves RODENTS as the definitive host and BEETLES as the intermediate host.
An order of nematodes of the subclass SECERNENTEA. Its organisms possess two or three pairs of dorsolateral caudal papillae.
A species of parasitic nematode found in the intestine of dogs. Lesions in the brain, liver, eye, kidney, and lung are caused by migrating larvae. In humans, these larvae do not follow normal patterns and may produce visceral larva migrans (LARVA MIGRANS, VISCERAL).
The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.
Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
A superfamily of nematodes. Most are intestinal parasites of ruminants and accidentally in humans. This superfamily includes seven genera: DICTYOCAULUS; HAEMONCHUS; Cooperia, OSTERTAGIA; Nematodirus, TRICHOSTRONGYLUS; and Hyostrongylus.
A genus of intestinal flukes of the family Echinostomatidae which consists of many species. They occur in man and other vertebrates. The intermediate hosts are frequently mollusks.

The Caenorhabditis elegans sex determination gene mog-1 encodes a member of the DEAH-Box protein family. (1/700)

In the Caenorhabditis elegans hermaphrodite germ line, the sex-determining gene fem-3 is repressed posttranscriptionally to arrest spermatogenesis and permit oogenesis. This repression requires a cis-acting regulatory element in the fem-3 3' untranslated region; the FBF protein, which binds to this element; and at least six mog genes. In this paper, we report the molecular characterization of mog-1 as well as additional phenotypic characterization of this gene. The mog-1 gene encodes a member of the DEAH-box family. Three mog-1 alleles possess premature stop codons and are likely to be null alleles, and one is a missense mutation and is likely to retain residual activity. mog-1 mRNA is expressed in both germ line and somatic tissues and appears to be ubiquitous. The MOG-1 DEAH-box protein is most closely related to proteins essential for splicing in the yeast Saccharomyces cerevisiae, but splicing appears to occur normally in a mog-1-null mutant. In addition to its involvement in the sperm-oocyte switch and control of fem-3, zygotic mog-1 is required for robust germ line proliferation and for normal growth during development. We suggest that mog-1 plays a broader role in RNA regulation than previously considered.  (+info)

The nuclear receptor superfamily has undergone extensive proliferation and diversification in nematodes. (2/700)

The nuclear receptor (NR) superfamily is the most abundant class of transcriptional regulators encoded in the Caenorhabditis elegans genome, with >200 predicted genes revealed by the screens and analysis of genomic sequence reported here. This is the largest number of NR genes yet described from a single species, although our analysis of available genomic sequence from the related nematode Caenorhabditis briggsae indicates that it also has a large number. Existing data demonstrate expression for 25% of the C. elegans NR sequences. Sequence conservation and statistical arguments suggest that the majority represent functional genes. An analysis of these genes based on the DNA-binding domain motif revealed that several NR classes conserved in both vertebrates and insects are also represented among the nematode genes, consistent with the existence of ancient NR classes shared among most, and perhaps all, metazoans. Most of the nematode NR sequences, however, are distinct from those currently known in other phyla, and reveal a previously unobserved diversity within the NR superfamily. In C. elegans, extensive proliferation and diversification of NR sequences have occurred on chromosome V, accounting for > 50% of the predicted NR genes.  (+info)

Reticulate evolution and the origins of ribosomal internal transcribed spacer diversity in apomictic Meloidogyne. (3/700)

Among root knot nematodes of the genus Meloidogyne, the polyploid obligate mitotic parthenogens M. arenaria, M. javanica, and M. incognita are widespread and common agricultural pests. Although these named forms are distinguishable by closely related mitochondrial DNA (mtDNA) haplotypes, detailed sequence analyses of internal transcribed spacers (ITSs) of nuclear ribosomal genes reveal extremely high diversity, even within individual nematodes. This ITS diversity is broadly structured into two very different groups that are 12%-18% divergent: one with low diversity (< 1.0%) and one with high diversity (6%-7%). In both of these groups, identical sequences can be found within individual nematodes of different mtDNA haplotypes (i.e., among species). Analysis of genetic variance indicates that more than 90% of ITS diversity can be found within an individual nematode, with small but statistically significant (5%-10%; P < 0.05) variance distributed among mtDNA lineages. The evolutionarily distinct parthenogen M. hapla shows a similar pattern of ITS diversity, with two divergent groups of ITSs within each individual. In contrast, two diploid amphimictic species have only one lineage of ITSs with low diversity (< 0.2%). The presence of divergent lineages of rDNA in the apomictic taxa is unlikely to be due to differences among pseudogenes. Instead, we suggest that the diversity of ITSs in M. arenaria, M. javanica, and M. incognita is due to hybrid origins from closely related females (as inferred from mtDNA) and combinations of more diverse paternal lineages.  (+info)

Acoel flatworms: earliest extant bilaterian Metazoans, not members of Platyhelminthes. (4/700)

Because of their simple organization the Acoela have been considered to be either primitive bilaterians or descendants of coelomates through secondary loss of derived features. Sequence data of 18S ribosomal DNA genes from non-fast evolving species of acoels and other metazoans reveal that this group does not belong to the Platyhelminthes but represents the extant members of the earliest divergent Bilateria, an interpretation that is supported by recent studies on the embryonic cleavage pattern and nervous system of acoels. This study has implications for understanding the evolution of major body plans, and for perceptions of the Cambrian evolutionary explosion.  (+info)

Characterization of endonuclease activity from excretory/secretory products of a parasitic nematode, Trichinella spiralis. (5/700)

Double-stranded endonuclease activity was demonstrated for the first time in the excretory/secretory (ES) products of a parasitic nematode, Trichinella spiralis, which can reorganize host muscle cells. The endonuclease introduced double-stranded breaks to the native DNA. The ES double-stranded endonuclease(s) was sequence nonspecific, with a pH optimum below 6, and required divalent cations as a cofactor. Its activity was inhibited by the Zn2+ ion. It was detected mainly in the ES products of the infective-stage larvae of T. spiralis collected at 37 degrees C and was present in much smaller amounts in samples collected at 43 degrees C and in the products of T. pseudospiralis, a nonencapsulated species. The activity of endonuclease was blocked by antibodies against ES products. Zymographic analysis showed that the endonuclease activity was associated with at least three molecular forms, designated approximately 25, 30 and 58 kDa, respectively.  (+info)

The C. elegans homeodomain gene unc-42 regulates chemosensory and glutamate receptor expression. (6/700)

Genes that specify cell fate can influence multiple aspects of neuronal differentiation, including axon guidance, target selection and synapse formation. Mutations in the unc-42 gene disrupt axon guidance along the C. elegans ventral nerve cord and cause distinct functional defects in sensory-locomotory neural circuits. Here we show that unc-42 encodes a novel homeodomain protein that specifies the fate of three classes of neurons in the Caenorhabditis elegans nervous system: the ASH polymodal sensory neurons, the AVA, AVD and AVE interneurons that mediate repulsive sensory stimuli to the nematode head and anterior body, and a subset of motor neurons that innervate head and body-wall muscles. unc-42 is required for the expression of cell-surface receptors that are essential for the mature function of these neurons. In mutant animals, the ASH sensory neurons fail to express SRA-6 and SRB-6, putative chemosensory receptors. The AVA, AVD and AVE interneurons and RME and RMD motor neurons of unc-42 mutants similarly fail to express the GLR-1 glutamate receptor. These results show that unc-42 performs an essential role in defining neuron identity and contributes to the establishment of neural circuits in C. elegans by regulating the transcription of glutamate and chemosensory receptor genes.  (+info)

Analysis of calsequestrin gene expression using green fluorescent protein in Caenorhabditis elegans. (7/700)

The calsequestrin gene of Caenorhabditis elegans is expressed in body-wall muscle cells during muscle development. In order to study the body-wall muscle specific regulation of the calsequestrin gene expression, approximately 2 kb upstream sequences of the calsequestrin gene were analyzed. Transcriptional fusion constructs utilizing green fluorescent protein as a reporter gene were made and microinjected to produce germ-line transformed transgenic C. elegans. The expression of green fluorescent protein was observed in the body-wall muscles of live transgenic animals under fluorescence microscopy. Deletion analyses of upstream sequences have revealed a putative promoter sequence and a regulatory element which appeared to enhance reporter gene expression. Both sequence elements are juxtaposed to constitute a 260 bp regulatory region approximately 260 bp upstream from the putative translational initiation codon. Several possible binding sites for transcription factors were identified including the sites for YY1 and NF-W2, a muscle specific zinc finger transcription factor, and an ubiquitous enhancer binding protein, respectively. Interestingly, this region also contains a 20 bp sequence element identical to those found in the mouse dystrophin gene, which suggests a possible role of this regulatory region in muscle specific gene regulation.  (+info)

Control of schistosomiasis pathology by combination of Sm28GST DNA immunization and praziquantel treatment. (8/700)

Today the control of schistosomiasis infection relies only on the use of praziquantel (PZQ) chemotherapy. However, PZQ treatment cannot prevent reinfection and progressive development of the pathology. We assessed in a mouse model the efficiency of a combined therapy, based on the combination of PZQ chemotherapy with Schistosoma mansoni 28-kDa glutathion S-transferase (Sm28GST) DNA vaccination, designed to limit the pathology. Following this combined therapy, the long-term survival of the mice was significantly enhanced in comparison with the survival of mice either vaccinated only or treated with PZQ only. In addition, the development of the pathology observed in the control groups was almost completely prevented in the vaccinated-PZQ-treated mice and was associated with a dramatic reduction of egg deposition in the tissues. We showed that PZQ treatment induced the unmasking of the native GST enzyme at the surface of the worms, thus permitting its neutralization by the antibodies raised by DNA immunization. This study provides insights into the synergistic mechanisms involved in an immunointervention strategy associated with chemotherapy for the control of a chronic infection and its associated pathology.  (+info)

GNC CoQ-10 - 100 mg: Coenzyme Q-10 Dietary Supplement GNC CoQ-10 supports heart health* and is beneficial for those taking Statin drugs. 120 soft gels 100 mg per serving Statin drugs can reduce the amount of natural CoQ-10 within the body. Supplementing with CoQ-10 helps replenish CoQ-10 levels within the body. CoQ-10
Product Page for CoQ-10 Enzyme 200 mg 30 Softgels made by schiff offering price, ingredients and full item description from betterlife
Leandro X. et, al, Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vaccine Development, https://doi.org/10.1021/acs.jproteome.9b00531 Nov. 15, 2019.. Schistosomes are blood-dwelling helminth parasites that cause schistosomiasis, a debilitating disease resulting in inflammation and, in extreme cases, multiple organ damage. Major challenges to control the transmission persist, and the discovery of protective antigens remains of critical importance for vaccine development. Rhesus macaques can self-cure following schistosome infection, generating antibodies that target proteins from the tegument, gut, and esophagus, the last of which is the least investigated. We developed a dissection technique that permitted increased sensitivity in a comparative proteomics profiling of schistosome esophagus and gut. Proteome analysis of the male schistosome esophagus identified 13 proteins encoded by microexon genes ...
An apparatus for killing insects in produce, which comprises an outer container; means for dividing a space enclosed by the outer container into first and second internal chambers; means for supporting a plurality of bulk produce bins in the first internal chamber; first and second air passage means for selectively allowing passage of air between the first internal chamber and the second internal chamber; means for circulating air in the second internal chamber successively through one of the air passage means, the first internal chamber, the other of the air passage means, and back into the second internal chamber; and means for heating the circulating air.
JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research. Watch our scientific video articles.
TY - JOUR. T1 - Report of the second internal workshop on human chromosome 5 mapping. AU - Westbrook, C. A.. AU - Neuman, W. L.. AU - Mcpherson, John Douglas. AU - Camper, S.. AU - Wasmuth, J.. AU - Plaetke, R.. AU - Williamson, R.. PY - 1992. Y1 - 1992. UR - http://www.scopus.com/inward/record.url?scp=0026677059&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026677059&partnerID=8YFLogxK. M3 - Article. C2 - 1362532. AN - SCOPUS:0026677059. VL - 61. SP - 226. EP - 231. JO - Cytogenetic and Genome Research. JF - Cytogenetic and Genome Research. SN - 1424-8581. IS - 4. ER - ...
Meaning and definition of the name Bandit. Learn the meaning of Bandit, learn about the origin of the name Bandit and find other information about the name Bandit.
36 playing cards to target compare and contrast. Print and laminate cards...stack and have students take turns drawing. Player/team with the most cards at the end is the winner. Also contains a visual cue for similarities and differences as well as a compare and contrast worksheet.
Perkara itu diumumkan oleh timbalan ketua pesuruhjaya SPRM (pengurusan dan profesionalisme), Datuk Zakaria Jaafar dalam satu sidang akhbar di ibupejabat suruhanjaya itu di Putrajaya hari ini ...
Septins are guanosine-5-triphosphate-binding proteins involved in wide-ranging cellular processes including cytokinesis, vesicle trafficking, membrane remodelling and scaffolds, and with diverse binding partners. Precise roles for these structural proteins in most processes often remain elusive. Identification of small molecules that inhibit septins could aid in elucidating the functions of septins and has become increasingly important, including the description of roles for septins in pathogenic phenomena such as tumorigenesis. The plant growth regulator forchlorfenuron, a synthetic cytokinin known to inhibit septin dynamics, likely represents an informative probe for septin function. This report deals with septins of the human blood fluke Schistosoma mansoni and their interactions with forchlorfenuron. Recombinant forms of three schistosome septins, SmSEPT5, SmSEPT7.2 and SmSEPT10, interacted with forchlorfenuron, leading to rapid polymerization of filaments. Culturing developmental stages ...
This module is particularly useful for those who are interested in morphological species identification of major plant-parasitic nematodes.
Effect of Sorghum-Sudangrass and Velvetbean Cover Crops on Plant-Parasitic Nematodes Associated with Potato Production in Florida
C57BL/6J mice were fed under four different experimental conditions for 17 weeks: normal diet (ND), high fat diet (HFD), HFD with 5% RJ, and HFD with 5% honey bee larva powder (BL). Spontaneous locomotor activity, hepatic triglyceride (TG) content, and blood parameters were examined. Gene and protein expressions of thermogenic uncoupling protein 1 (UCP1) and mitochondrial cytochrome c oxidase subunit IV (COX-IV) in BAT and WAT were investigated by qPCR and Western blotting analysis, respectively ...
Above: A nematode seen under a microscope. UF/IFAS photo by Tyler Jones.. A parasite is an organism that lives on or inside of another organism, weakening its host but usually not killing it. This feature distinguishes it from a parasitoid, which typically does kill its host.. Words related to parasite include parasitic (adjective), parasitism (noun) and parasitize (verb). Obligate parasitism occurs when an organism can only survive by its parasitic relationships with another organism.. Plant-parasitic nematodes are one example of a parasitic bug. These nematodes are very small and may only be visible with a microscope. Like other nematodes, plant-parasitic nematodes live in the soil, where they feed on plants.. Many of these parasitic nematodes attack plants from the outside with a spear-like body part called a stylet. Because of this behavior we call them ectoparasites, parasites that live on the outside of their host.. Other nematodes live inside a plant, making them endoparasites. Root-knot ...
Platyhelminthes tutorial all along with the key concepts of Characteristics of Platyhelminthes, Triploblastic Condition of Platyhelminthes, Acoelomate Condition, Classification of Flatworms, Structure Adults, Life Cycle of Tape Worm and Life cycle of Taenia
Get 24/7 Phylum Platyhelminthes Homework Help Online from experts on Transtutors.com. ✓25% discount ✓100% Cashback* ✓3254+ Phylum Platyhelminthes Experts. Ask Now ! Get 100% error-free solutions at affordable prices
Foreword. Foreword to the first edition. Preface. Preface to the first edition. 1 Introduction or Exploration. Exercises. 2 Main Ideas: Gittins Index. 2.1 Introduction. 2.2 Decision processes. 2.3 Simple families of alternative bandit processes. 2.4 Dynamic programming. 2.5 Gittins index theorem. 2.6 Gittins index. 2.7 Proof of the index theorem by interchanging bandit portions. 2.8 Continuous-time bandit processes. 2.9 Proof of the index theorem by induction and interchange argument. 2.10 Calculation of Gittins indices. 2.11 Monotonicity conditions. 2.12 History of the index theorem. 2.13 Some decision process theory. Exercises. 3 Necessary Assumptions for Indices. 3.1 Introduction. 3.2 Jobs. 3.3 Continuous-time jobs. 3.4 Necessary assumptions. 3.5 Beyond the necessary assumptions. Exercises. 4 Superprocesses, Precedence Constraints and Arrivals. 4.1 Introduction. 4.2 Bandit superprocesses. 4.3 The index theorem for superprocesses. 4.4 Stoppable bandit processes. 4.5 Proof of the index theorem ...
The Belly Bandit post-pregnancy wrap might help your tummy return to its former glory faster. Learn more in this Belly Bandit wrap review.
Buy Smokey and the Bandit [Includes Digital Copy] [UltraViolet] [Blu-ray] 1977 online and read movie reviews at Best Buy. Free shipping on thousands of items.
Magazin online Primadrogherie.ro. Cumpără online Q-absorb (CoQ-10 100mg) (30 capsule), Jarrow Formulas la cel mai bun preț. Află promoția noastră. Dorești consiliere telefonică? Îți răspundem cu drag la 0732.258.382
Use your best strategy and get rid of the animals trying to destroy your territory. Place your tools and click on BEGIN RAID to let the animals come and kill them automatically. Play with your mouse.
abstract = {We have identified and characterized a Macrophage Migration Inhibitory Factor (MIF) family member in the Lophotrochozoan invertebrate, Biomphalaria glabrata, the snail intermediate host of the human blood fluke Schistosoma mansoni. In mammals, MIF is a widely expressed pleiotropic cytokine with potent pro-inflammatory properties that controls cell functions such as gene expression, proliferation or apoptosis. Here we show that the MIF protein from B. glabrata (BgMIF) is expressed in circulating immune defense cells (hemocytes) of the snail as well as in the B. glabrata embryonic (Bge) cell line that has hemocyte-like features. Recombinant BgMIF (rBgMIF) induced cell proliferation and inhibited NO-dependent p53-mediated apoptosis in Bge cells. Moreover, knock-down of BgMIF expression in Bge cells interfered with the in vitro encapsulation of S. mansoni sporocysts. Furthermore, the in vivo knock-down of BgMIF prevented the changes in circulating hemocyte populations that occur in ...
Two species-specific PCR primer pairs were developed for identifying the two nematode species, Bursaphelenchus xylophilus and B. mucronatus. The primer pairs were developed from the sequence of ribosomal DNA (rDNA) repeats to produce DNA fragments of different lengths by PCR amplification. The DNA fragments for B. mucronatus and B. xylophilus were 210 bp and 557 bp, respectively. When mixed, neither primer pair inhibited the PCR amplification of the other. Five isolates of B. xylophilus and four isolates of B. mucronatus showed different band profiles of PCR products between the two species, but identical profiles among isolates of the same species.
Pine wilt disease (PWD) is a complex disease integrating three major agents: the pathogenic agent, the pinewood nematode Bursaphelenchus xylophilus; the insect-vector Monochamus spp.; and the host pine tree, Pinus sp. Since the early 80s, the notion that another pathogenic agent, namely bacteria, may play a role in PWD has been gaining traction, however the role of bacteria in PWD is still unknown. The present work supports the possibility that some B. xylophilus-associated bacteria may play a significant role in the development of this disease. This is inferred as a consequence of: (i) the phenotypic characterization of a collection of 35 isolates of B. xylophilus-associated bacteria, in different tests broadly used to test plant pathogenic and plant growth promoting bacteria, and (ii) greenhouse experiments that infer the pathogenicity of these bacteria in maritime pine, Pinus pinaster. The results illustrate the presence of a heterogeneous microbial community associated with B. xylophilus and the
Molecular Phylogeny of Geographical Isolates of Bursaphelenchus xylophilus Implications on the Origin and Spread of this Species in China and Worldwide
Bursaphelenchus luxuriosae n. sp. is described and figured. Specimens were collected from a 2-week-old culture on Botrytis cinerea. The new species is characterised by a body length of 897 (710-1159) μm in the female and 745 (621-887) μm in the male, relatively robust body (a = 33-39 in the female and 27-30 in the male), stylet ca 14 (11-16) μm long, four lines in the lateral field, the large (27-30 μm) arcuate spicule with a terminal cucullus, seven (2 + 1 + 2 + 2) male caudal papillae, the long, well developed vulval flap and the shape of the female tail which is long, tapered, and ventrally bent when killed by heat with an irregular or roughened dorsal contour near the tip and an irregular terminus. The new species is considered to belong to the Bursaphelenchus xylophilus group of the genus Bursaphelenchus and is most closely related to B. conicaudatus and B. fraudulentus in spicule shape, vulval flap and 'a' values of males and females. It is easily distinguished from these two species
...AMES Iowa -- There are numerous plant-parasitic nematodes in the worl...Now Iowa State University researchers have contributed to the release...Sequencing the genome is a critical step toward comprehensively unders... This is considered to be one of if not the most important plant-para...,ISU,researchers,help,map,first,plant-parasitic,nematode,genome,sequence,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
The blood flukes Schistosoma mansoni and Schistosoma japonicum inflict immense suffering as agents of human schistosomiasis. Previous investigations have found the nervous systems of these worms contain abundant immunoreactivity ...
Mutations in the clk-1 gene of the nematode Caenorhabditis elegans result in an average slowing of a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging. In yeast, a CLK-1 homologue is absolutely required …
Barker, K.R., G.A. Pederson, and G.L. Windham. 1998. Plant and Nematode Interactions. ASA, CSSA, and SSSA, Madison, WI.. Bird, A.F. and J. Bird. 1991. The Structure of Nematodes, Second edition.Academic Press Inc. London.. Blaxter, M.L., P. De Ley, J.R. Garey, L.X. Liu, P. Scheldeman, A. Vierstraete, J.R. Vanfleteren, L.Y. Mackey, M. Dorris, L.M. Frisse, J.T. Vida, K.W. Thomas, K.W. 1998. A molecular evolutionary framework for the phylum nematoda. Nature 392:71-75.. Campbell, J.F. and H.K. Kaya. 1999. How and why a parasitic nematode jumps. Nature 397: 485-486.. Chen, Z.X., and D.W. Dickson. 2004. Nematology: Advances and Perspectives Vol. 1: Nematode Morphology, Physiology and Ecology. CABI:Walllingford.. Chen, Z.X., S.Y. Chen, and D.W. Dickson. 2004. Nematology: Advances and Perspectives Vol. II: Nematode Management and Utilization. CABI:Wallingford.. Fisher, J.M. and D.J. Raski. 1967. Feeding of Xiphinema index and X. diversicaudatum. Proceeding of the Helminthological Society of Washington ...
Phylum Platyhelminthes Habit and habitat: Members of this phylum are mainly ectoparasite or endoparasite of other organisms but a few species are free livi
Find details on Taenia multiceps in dogs including diagnosis and symptoms, active forms, resting forms, clinical effects, treatment and more. All information is peer reviewed.
Hey all, Im on the verge of getting a new Macbook Pro and among the annoyances I know of (no DVD = no replacing it with a second internal HD) Im wondering about the ones I dont? I know there was talk about switching Izzy fully over to AV Foundation but...
Increasing attacks by groups of bandits along the main routes through Nigers northern Agadez region threaten the security of travellers and jeopardize safe transport and commerce.
Bandit, the worlds heaviest raccoon, died Saturday at his owners house in Palmerton, ending an eventful 10-year life that included international attention and listings as a Guinness World Record
The genome of the microscopic worm Caenorhabditis briggsae has been sequenced, and shows some remarkable differences from the genome of the better known - and physically similar - C. elegans.
Fangrrls is about kicking down doors, breaking boundaries and celebrating female fans with fun, witty and entertaining content ...
1. Baldwin, J.G., Nadler, S.A., and Wall, D.H. 1997. Nematodes: Pervading the Earth and Linking all Life. Pp. 176-191. In: Raven, P.H. (ed.). National Academy Press, Washington, D.C. 625 pp.. 2. Bargmann, C. I. 1998. Neurobiology of the Caenorhabditis elegans genome. Science 282:2028-2033.. 3. Bargmann, C. I. And Mori, I. 1997. Chemotaxis and Thermotaxis. Pp. 717-737. In: Riddle, D.L., Blumenthal, T., Meyer, B.J. and Priess, J.R. (eds). C. elegans II. Cold Spring Harbor Laboratory Press, Plainview, NY 1222 pp.. 4. Bird, D.M. and Opperman, C. H. 1998. Caenorhabditis elegans. J. Nematol. 30:299-308.. 5. Bird, D.M., Opperman, C.H., Jones S.J.M., and Baillie, D.L. 1999. The Caenorhabditis elegans gemome: a guide in the post genomics age. Annu. Rev. Phytopathol. 37:247-265.. 6. Blaxter, M. 1998. Caenorhabditis elegans is a nematode. Science 282:2041-2046.. 7. Blaxter, M. and Bird, D. 1997. Parasitic nematodes. Pp. 851-878. In: Riddle, D.L., Blumenthal, T., Meyer, B.J. and Priess, J.R. (eds). C. ...
Define phylum Platyhelminthes. phylum Platyhelminthes synonyms, phylum Platyhelminthes pronunciation, phylum Platyhelminthes translation, English dictionary definition of phylum Platyhelminthes. Noun 1. phylum Platyhelminthes - flatworms Platyhelminthes animal kingdom, Animalia, kingdom Animalia - taxonomic kingdom comprising all living or extinct...
Pine wilt disease (PWD) caused by pine wood nematode (PWN), Bursaphelenchus xylophilus, is the most destructive diseases of pine and poses a threat of serious economic losses worldwide. Although several of the mechanisms involved in disease progression have been discovered, the molecular response of Pinus massoniana to PWN infection has not been explored. We constructed four subtractive suppression hybridization cDNA libraries by taking time-course samples from PWN-inoculated Masson pine trees. One-hundred forty-four significantly differentially expressed sequence tags (ESTs) were identified, and 124 high-quality sequences with transcriptional features were selected for gene ontology (GO) and individual gene analyses. There were marked differences in the types of transcripts, as well as in the timing and levels of transcript expression in the pine trees following PWN inoculation. Genes involved in signal transduction, transcription and translation and secondary metabolism were highly expressed after 24
Supplementary MaterialsTable S1: Gene Ontology mappings for clusters. expansin proteins. Introduction Expressed sequence tags (ESTs) have proven to be one of the most rapid routes to gene discovery of any organism for which a cDNA library is available [1]. In addition, large-scale EST analysis can be used to estimate gene expression levels in specific life stages or tissues and are useful tools for annotation of genome sequences [1], [2]. EST analysis has been widely applied to study the biology of nematodes. Over 1.5 million ESTs from more than 63 species, including free-living nematodes, animal-parasitic and plant-parasitic species are available in dbEST (GenBank, 1 October 2012). To date, over 125,000 EST sequences from twenty different plant-parasitic nematodes are in dbEST. This information is of great significance for studying nematode biology, especially for the identification of effectors. Plant-parasitic nematode effectors, defined Maraviroc distributor here as proteins secreted by the ...
272 common core vocabulary cards for grades K-5. (Specific grade is included on each card). Have students use the word in a sentence, give a synonym, define the word in their own words or complete a vocabulary map (included in the packet). Great for
Ovarele şi testiculele sunt perechi iar la suprafaţa corpului sunt prezente papile adezive şi papile senzitive. La cestodari corpul este unitar, foliaceu sau în formă de desen platyhelminthes, lipsit de scolex şi de organe de fixare. Scopul lectiei:.
Is a sexy masked bandit/cat burglar too much to ask for? Really, Universe? REALLY? Just one of these, just ONE in the rats nest of banditry that is My Neighborhood? Guess not, eh? Well, let me tell you about the cat burglar/bandit who broke into my apartment recently. S/he/it looked nothing like any of the…
Flatworm: Flatworm, any of the phylum Platyhelminthes, a group of soft-bodied, usually much flattened invertebrates. A number of flatworm species are free-living, but about 80 percent of all flatworms are parasitic-i.e., living on or in another organism and securing nourishment from it. They are bilaterally
The nematode Caenorhabditis elegans may hold the key to brain-like computational architectures: Si elegans will provide the scientific community with a reconfigurable, scalable and modular neuromimetic open-access computational platform to explore neural principles that give rise to complex behaviour and to derive a neuro-inspired technological blueprint for a new era of brain-like computational architectures.The Si elegans project started on April 1st 2013. ...
The distinguishing characteristics of this method are well-developed metacorpus from J2 to adult, a short stylet 11-15 μm in adults, typically 1mm in length. Females have the vulva located two-thirds body length and have a vulval flap. Females have a long post uterine sac and a rounded tail. Males have seven papillae in the tail region, distinct spicules, and bursa shaped as a spade. [3]. ...
A system comprising an ice-cream or a screen, and arranged to ensure the sealing and / or anti-scratch protection of an apparatus for displaying information visible to a user through the ice or the screen, comprises a first layer of material (1) made of unbreakable transparent plastic polymer, the first layer of material (1) being arranged on said apparatus so that a first face is arranged on the information side and a second face on the user side. The system comprises a second layer of transparent glass material (2) having an anti-scratch surface, in particular a sapphire crystal, superimposed on the first layer (1) by means of positioning means (8), the second layer (2) having an external face arranged on the user side and a second internal face arranged on the information side. The positioning means (8) comprise a protuberance or a groove arranged on the outer periphery of the first material (1) so that these positioning means (8) surround the second layer of material (2) which covers the first
Written By Jenny Pavlovic. We lost Bandit to multiple myeloma in March, and our little pack continues to find its way. When Bandits body was failing and I realized he was in pain, it became apparent that he was ready to go. But I could tell he was concerned about how we would manage without him. So we spent time with him doing things he wanted to do for one last time, and cherished our last hours together. I reassured him that we didnt want him to be in pain any longer, and that somehow we would get along without him. Bandit wanted us to be happy and celebrate life.. Australian Cattle Dogs usually live longer than ten years, so whenever I begin to wish that wed had more time, I remember that a miracle brought us together in the first place. One step this way or that and our life together would not have happened at all. Im grateful we had that chance meeting.. Over the past ten years, I think Bandit has influenced my life more than any other being. We lived together day in and day out. He ...
Since 1999, Bandits Goalie School has prided itself on training, educating and mentoring some of the best goalies in North America. The relationships that ha...
This uncovered version is the original tummy tucker that started the craze! Engineered with unique, medical-grade elastic, our powerful, latex-free, post-pregnancy secret can be adjusted to fit around the belly, waist and hips to create the ultimate slimming result. Our unique and powerful Stretch and Compress™ technology creates a garment that can help you shrink down to your pre-pregnancy size. ...
The bandits were banished from the farm. We released them in fields far, far away from our ducks.. Much more happened this week that I hope to eventually get the opportunity to share. My weekly blogging schedule has been a bit derailed by the 500 preschoolers I have 45 days to meet, a rapidly approaching deadline for an article, the start of a new semester, and the contemplation of how I wind up in these situations.. ...
Rather than me going through the notes and boring you, today you will be using this website to go over the notes, videos, and pictures at your own speed. You will gather notes through answering questions which gives you examples of questions I could ask on the simple invertebrates test while adapting my notes to fully address the question. Feel free to use other materials/videos to explore these phylum and help clarify if you need. If you would like me to check on any of your answers/diagrams, please let me know ...
The main focus of our research is the study of neuronal function and dysfunction, using the nematode Caenorhabditis elegans as a model organism. Among...
What happens when you cross post-apocalyptic vehicular combat, dualing armies of biker clones, a surf rock soundtrack that sounds right out of Six String Samurai, and more explosions than Michael Bays wet dreams?
RM400 juta untuk mengendalikan pilihan raya untuk 222 kerusi Parlimen bermaksud purata kos untuk pengendalian sebuah kawasan Parlimen ialah RM1.8 juta! Ini merupakan satu angka yang besar memandangkan had perbelanjaan untuk seseorang calon yang bertanding di peringkat Parlimen hanyalah RM200 ribu, kata Loke dalam sidang media di lobi Parlimen pagi ini. ...
... are of major medical and veterinary importance since they act as vectors of parasites (helminths, mainly trematodes ... Immunological, cytogenetical, enzyme electrophoresis studies, and DNA-based approaches have demonstrated extensive homoplasy in ...
Hunt P. W.; Lello J. (2012). "How to make DNA count: DNA-based diagnostic tools in veterinary parasitology". Veterinary ... Of all the known helminth species, the most important helminths with respect to understanding their transmission pathways, ... Specific helminths can be identified through microscopic examination of their eggs (ova) found in faecal samples. The number of ... Helminths may cause iron-deficiency anemia. This is most severe in heavy hookworm infections, as Necator americanus and ...
Citing examples of the Schistosoma mansoni, a parasitic worm whose eggs release a protein which can bind to DNA and replicate ... alongside it, and Helminths, parasitic worms which have been used to treat autoimmune disorders, as possibilities for ...
Co-infection with DNA viruses such as HTLV-1, herpes simplex virus-2, varicella zoster virus and cytomegalovirus may enhance ... Frequent exposure to helminth infections, which are endemic in Africa, activates individual immune systems, thereby shifting ... 1986). "Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses". PNAS. 83 (24): 9759 ... Both reverse transcription of the HIV-1 genome and the rate of transcription of proviral DNA rely upon the activation state of ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[citation needed] DNA ... Other infectious organisms which cause cancer in humans include some bacteria (e.g. Helicobacter pylori ) and helminths (e.g. ... The altered DNA base can cause errors during DNA replication that have mutagenic and carcinogenic potential. Thus H. pylori- ... DNA is nucleophilic; therefore, soluble carbon electrophiles are carcinogenic, because DNA attacks them. For example, some ...
... 500 mg twice daily resulted in a decrease in serum HBV DNA in all of 4 HBeAg-positive patients, with undetectable ... It is also an effective treatment option for infections caused by other protozoa and helminths (e.g., Entamoeba histolytica, ... Seven of 8 HBeAg-negative patients treated with nitazoxanide 500 mg twice daily had undetectable HBV DNA and 2 had loss of ... Nitazoxanide also inhibits the replication of a broad range of other RNA and DNA viruses including respiratory syncytial virus ...
DNA samples would be required when pet licenses come up for renewal. Within a year, a database of some 12,500 registration- ... Clinically infected people have helminth infection and rarely blindness. Motocrotte - motorcycle-based solution for cleaning ... The Germans consider DNA testing to match poop to pooch". Science. Popular Science. Retrieved 2006-06-06. "The Scoop on Poop". ... The Germans consider DNA testing to match poop to pooch". Science. Popular Science. Retrieved 2006-06-06. Svobodová V, Svoboda ...
... , or T. leonina, is an ascarid nematode, a worldwide distributed helminth parasite which is in a division of ... Petrigh, R. S.; Martínez, J. G.; Mondini, M.; Fugassa, M. H. (2019). "Ancient parasitic DNA reveals Toxascaris leonina presence ... List of parasites (human) Toxocariasis Maizels RM, Yazdanbakhsh M (2003). "Immune regulation by helminth parasites: cellular ...
For example, helminth infections cause potent and highly polarized immune response characterized by increased T-helper cell ... Recent research has focused on the development of a DNA-based tool that can be used for diagnosis of infection, specific ... As compared to other helminths, hookworm is able to survive in much hotter conditions and was highly prevalent throughout the ... Knowles SC (August 2011). "The effect of helminth co-infection on malaria in mice". Int. J. Parasitol. 41 (10): 1041-51. doi: ...
They can be either RNA or DNA viruses consisting of a single or double strand of genetic material (RNA or DNA respectively), ... Many types of helminth including flukes and cestodes have complete life cycles involving two or more hosts. By far the largest ... Various species of helminth castrate their hosts (such as insects and snails). This may happen directly, whether mechanically ... Much of the thinking on types of parasitism has focussed on terrestrial animal parasites of animals, such as helminths. Those ...
eggs In cases where the intact bodies of parasites are not found, protein or DNA from the parasite may still be present. ... Endoparasites (such as protozoans and helminths), tend to be found inside the host, while ectoparasites (such as ticks, lice ... In some cases, relatively intact soft-bodied adult helminths and ectoparasitic arthropods have been found. All of these forms ... Dittmar K, Mamat U, Whiting M, Goldmann T, Reinhard K, Guillen S (2003). "Techniques of DNA-studies on prehispanic ...
Dubey, J.P.; Pande, B.P. (1964). "A note on some helminths of the wild duck (Anas poecilorhyncha)". Indian Journal of ... A 2014 study, however, shows that there is discordance between the phylogenies obtained using nuclear DNA sequences; the Indian ... Other trematodes recorded in the species include Psilochasmus oxyurus while helminths include Opisthorchis obsequens, ... Mitochondrial DNA. 26 (2): 265-266. doi:10.3109/19401736.2013.823191. ISSN 1940-1736. PMID 24021013. S2CID 37147471. Jain, G. P ...
They also fight helminth (worm) colonization and may be slightly elevated in the presence of certain parasites. Eosinophils are ... High concentrations of these DNA traps are known to cause cellular damage, as the granules they contain are responsible for the ... After maturation, eosinophils circulate in blood and migrate to inflammatory sites in tissues, or to sites of helminth ... where the breaking of the cell releases eosinophilic granules found in extracellular DNA traps. ...
Brooker S, Clements AC, Bundy DA (2006). Global epidemiology, ecology and control of soil-transmitted helminth infections. Adv ... Recent research has focused on the development of a DNA-based tool that can be used for diagnosis of infection, specific ... Knowles SC (August 2011). "The effect of helminth co-infection on malaria in mice". Int. J. Parasitol. 41 (10): 1041-51. doi: ... The term "hookworm" is sometimes used to refer to hookworm infection.[11] A hookworm is a type of parasitic worm (helminth). ...
Sequencing DNA from an environmental sample is known as metagenomics. Sewage also contains environmental persistent ... and Parasites such as helminths and their eggs (e.g. ascaris (roundworm), ancylostoma (hookworm), trichuris (whipworm)) Sewage ... Much more sensitive and specific testing can be accomplished with DNA sequencing, such as when looking for rare organisms, ...
M. squamulosus is one of 8 genera of lizards in southern Africa that have been reported to harbor helminths These helminths ... More recent molecular phylogenetic analysis of mitochondrial DNA and nuclear DNA markers determined that it did not group with ... Mayer, W.; Pavlicev, M. (2007). "The phylogeny of the family Lacertidae (Reptilia) based on nuclear DNA sequences: Convergent ... ISSN 0040-4403 Goldberg, Stephen; Bursey, Charles (2002). "Helminths of seven species of lacertid lizards from southern Africa ...
115-119 Echi, P. C., Suresh, K., Sanil, G., Iyaji, F. O., Nwani, C. D., & Ejere, V. C. (2015). Mitochondrial DNA resolution of ... "Helminth parasites of pirarucu, Arapaima gigas (Schinz, 1822) (Osteoglossiformes: Arapaimidae) from Araguaia River, State of ...
Biological Invasions 14:127-137.[2]. Pavljuchenko, O. V. (2005) The first record of the helminth Aspidogaster conchicola ( ... Discovery and DNA Barcoding of the Invasive Chinese Pond Mussel Sinanodonta Woodiana in Myanmar". Tropical Conservation Science ...
Many times, viral pathogens enter the lytic cycle; this is when the virus inserts its DNA or RNA into the host cell, replicates ... Pathogens include bacteria, fungi, protozoa, helminths, and viruses. Each of these different types of organisms can then be ... The lysogenic cycle, however, is when the viral DNA is incorporated into the host genome, allowing it to go unnoticed by the ... Viruses can also infect the host with virulent DNA, which can affect normal cell processes (transcription, translation, etc.), ...
... dna, cruciform MeSH D13.444.308.300 - dna, fungal MeSH D13.444.308.315 - dna, helminth MeSH D13.444.308.324 - dna, intergenic ... dna adducts MeSH D13.444.308.142 - dna, a-form MeSH D13.444.308.148 - dna, algal MeSH D13.444.308.150 - dna, antisense MeSH ... dna, bacterial MeSH D13.444.308.227 - dna, c-form MeSH D13.444.308.243 - dna, catalytic MeSH D13.444.308.283 - dna, circular ... dna, plant MeSH D13.444.308.435.275 - dna, chloroplast MeSH D13.444.308.442 - dna, protozoan MeSH D13.444.308.442.200 - dna, ...
It was conceived as a large scale DNA sequencing centre to participate in the Human Genome Project, and went on to make the ... WormBase ParaSite, a database for the genomics for parasitic helminths (both Nematodes and Platyhelminthes). Scientific ... "Genetics lab told to hand back African tribes' DNA". sanger.ac.uk Coordinates: 52°05′N 0°11′E / 52.083°N 0.183°E / 52.083; ... It is also part of the GENCODE and ENCODE research programmes to create an encyclopaedia of DNA elements.[citation needed] The ...
Morgan, E.R.; Shaikenov, B.; Torgerson, P.R.; Medley, G.F.; Milner-Gulland, E.J. (2005). "Helminths of saiga antelopes in ... "Ancient DNA sequences point to a large loss of mitochondrial genetic diversity in the saiga antelope (Saiga tatarica) since the ... "Mitochondrial DNA variation and population structure of the Critically Endangered saiga antelope Saiga tatarica". Oryx. 40: 103 ...
They do not contain any DNA or RNA and cannot replicate other than to convert already existing normal proteins to the misfolded ... Helminths) are macroparasites that can be seen by the naked eye. Worms live and feed in their living host, receiving ... This type of pathogen is not cellular, and is instead composed of either RNA (Ribonucleic acid), or DNA (Deoxyribonucleic acid ...
PCR and RFLP are used to detect and amplify parasite DNA found in the feces, blood, or tissue of the host. These techniques are ... foetus Trypanosoma brucei Trypanosoma equiperdum Veterinary helminthology is focused on veterinary important helminth parasites ... Molecular biological methods involve studying the DNA of the parasite in order to identify it. ...
Shimalov, V. V.; Shimalov, V. T. "Helminth fauna of snakes (Reptilia, Serpentes) in Belorussian Polesye". Parasitology, 86 (4 ... as inferred from mitochondrial DNA sequence data]. Molecular Ecology, 15 (2006), 3425-3437 ...
2006). "Mitochondrial DNA variation and population structure of the Critically Endangered saiga antelope Saiga tatarica". Oryx ... Morgan, E.R.; Shaikenov, B.; Torgerson, P.R.; Medley, G.F.; Milner-Gulland, E.J. (2005). "Helminths of saiga antelopes in ... Zhao ShaSha i inni, Microsatellite and mitochondrial DNA assessment of the genetic diversity of captive Saiga antelopes (Saiga ... "Ancient DNA sequences point to a large loss of mitochondrial genetic diversity in the saiga antelope (Saiga tatarica) since ...
DNA fingerprinting can differentiate between D. medinensis and D. insignis, which is important to efforts to eradicate ... The effort to eradicate infections has focused mainly stopping the helminth at various points in its life cycle. Preventative ...
Helminth eggs that are indicated in wastewater and sludge come from soil-transmitted helminths (STHs) which include Ascaris ... and sequenced the DNA of the fungi the soil contained. They found eight indicator species for soil pH: four that were only ... These methods make it possible for helminth ova to be within the healthy requirements of ≤1 helminth ova per liter. Dehydration ... protozoa and helminths) and can in extreme cases survive for several years in soil. Typically, helminth eggs are found in water ...
Viruses can be either RNA or DNA viruses consisting of a single or double strand of genetic material (RNA or DNA) respectively ... "Helminth Parasites". Australian Society of Parasitology. Retrieved 9 October 2017.. *^ "Pathogenic Parasitic Infections". PEOI ... Various species of helminth castrate their hosts (such as insects and snails). This may be directly, whether mechanically by ... It infects its host, Escherichia coli, by injecting its DNA through its tail, which attaches to the bacterium's surface. ...
Later, DNA sequencing of acanthocephalans sampled form the mole crab Emerita analoga in the Pacific and E. talpoida in the ... Karl A. Mayer, Murray D. Dailey & Melissa A. Miller (2003). "Helminth parasites of the southern sea otter Enhydra lutris nereis ... DNA sequences were used to test whether the species Profilicollis bullocki in South America was genetically distinct from ...
An ancient DNA study published in 2015 characterized the rapidly evolving mitochondrial control region of one of these ... Krone, O., Stjernberg, T., Kenntner, N., Tataruch, F., Koivusaari, J., & Nuuja, I. (2006). Mortality factors, helminth burden, ... Studies of microsatellite and mitochondrial DNA in white-tailed eagles from north-central Europe have shown that the recovering ... and classification of the Accipitridae based on DNA sequences of the RAG‐1 exon. Journal of Avian Biology, 38(5), 587-602. ...
... as well as of protozoan and helminth parasites.[30] Bacterial diseases carried by fleas include murine or endemic typhus[29]: ... 18S and 28S ribosomal DNA, cytochrome oxidase II, and elongation factor 1-alpha) for 128 flea taxa from around the world. The ...
"DNA India. 19 November 2014. Retrieved 10 March 2015.. *^ "More than 40m Pakistanis defecate openly: Unicef - Pakistan". Dawn. ... 2014). "Effectiveness of a rural sanitation programme on diarrhoea, soil-transmitted helminth infection, and child malnutrition ...
2004). "Helminth infection modulates the development of allergen-induced airway inflammation". Int. Immunol. 16 (4): 585-96. ... In systemic lupus there are autoantibodies to DNA, which cannot evoke a T cell response, and limited evidence for T cell ... 2008). "Helminth Infection with Litomosoides sigmodontis Induces Regulatory T Cells and Inhibits Allergic Sensitization, Airway ... Induction of autoantibodies against tyrosinase-related proteins following DNA vaccination: Unexpected reactivity to a protein ...
Parasites carried include cysts of protozoa, e.g. Entamoeba histolytica and Giardia lamblia and eggs of helminths; e.g., ... "In Kimura H, Suzuki A (eds.). New Research on DNA Damages. New York: Nova Science Publishers. pp. 1-47. ISBN 978-1-60456-581-2 ... Oxidative DNA damage 8-hydroxydeoxyguanosine in houseflies was found in one study to increase with age and reduce life ... Holmes GE, Bernstein C, Bernstein H (September 1992). "Oxidative and other DNA damages as the basis of aging: a review". ...
From the Dolan DNA Learning Center of Cold Spring Harbor Laboratory.. *RNAi screens in C. elegans in a 96-well liquid format ... "RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects". Parasitology. 134 (Pt 5 ... so it does not modify or change DNA in a deleterious effect.[166] SiRNA can also be used to produce a specific response in a ... nine miRNAs have been identified as epigenetically altered and effective in down regulating DNA repair enzymes.[32] ...
Since the gene rearrangement leads to an irreversible change in the DNA of each cell, all progeny (offspring) of that cell ... parasites including helminths and toxins.[2] Like cytotoxic T cells, most of the CD4+ helper cells die on resolution of ... Diversity is generated by a cytosine deaminase-mediated rearrangement of LRR-based DNA segments.[34] There is no evidence for ...
Do Dolan DNA Learning Center do Cold Spring Harbor Laboratory.. *Cribado de RNAi en C. elegans en formato líquido de 96 pozos e ... "RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects". Parasitology 134 (Pt 5): ... "Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing". Nucleic Acids Res 34 (21): 6233-46. PMC ...
... found in DNA upstream of each constant region gene (except in the δ-chain). The DNA strand is broken by the activity of a ... helminths, allergens). ... "Roles of nonhomologous DNA end joining, V(D)J recombination, ... RAG proteins play an important role with V(D)J recombination in cutting DNA at a particular region.[39] Without the presence of ... and class switch recombination in chromosomal translocations". DNA Repair (Amst.). 5 (9-10): 1234-1245. doi:10.1016/j.dnarep. ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[33] DNA damages are ... Other infectious organisms which cause cancer in humans include some bacteria (e.g. Helicobacter pylori [2][3]) and helminths ( ... a b Bernstein C, Prasad AR, Nfonsam V, Bernstein H. (2013). DNA Damage, DNA Repair and Cancer, New Research Directions in DNA ... www.intechopen.com/books/new-research-directions-in-dna-repair/dna-damage-dna-repair-and-cancer ...
Transformation involves the transfer of DNA from a donor cell to a recipient cell and the integration of the donor DNA into the ... Some eukaryotic organisms, including a number of protozoa and helminths, are human parasites. ... They do not contain any DNA or RNA and cannot replicate other than to convert already existing normal proteins to the misfolded ... Viruses are small particles, typically between 20 and 300 nanometers in length,[15] containing RNA or DNA. Viruses require a ...
Helminth's relationship to humans as hosts should be classified as mutualistic or symbiotic.[citation needed] ... "Combination of apigenin treatment with therapeutic HPV DNA vaccination generates enhanced therapeutic anti tumor effects". J. ... Co-evolution with helminths has shaped some of the genes associated with Interleukin expression and immunological disorders, ... Reddy A, Fried B (January 2009). "An update on the use of helminths to treat Crohn's and other autoimmunune diseases". ...
Smith, J. D.; Addison, E. M.; Joachim, D. G.; Smith, L. M.; Quinn, N. W. S. (1986). "Helminth parasites of Canada lynx (Felis ... Schwartz, M. K.; Mills, L. S.; McKelvey, K. S.; Ruggiero, L. F.; Allendorf, F. W. (2002). "DNA reveals high dispersal ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[citation needed] DNA ... Other infectious organisms which cause cancer in humans include some bacteria (e.g. Helicobacter pylori [2][3]) and helminths ( ... The altered DNA base can cause errors during DNA replication that have mutagenic and carcinogenic potential. Thus H. pylori- ... DNA is nucleophilic; therefore, soluble carbon electrophiles are carcinogenic, because DNA attacks them. For example, some ...
Liu GH, Gasser RB, Nejsum P, Wang Y, Chen Q, Song HQ, Zhu XQ (2013). "Mitochondrial and nuclear ribosomal DNA evidence supports ... which is a type of helminth. The name whipworm refers to the shape of the worm; they look like whips with wider "handles" at ... there is currently a paucity of research devoted to encoding the DNA of each and every species. As a result, Trichuris species ... studies have been conducted to differentiate similar Trichuris species based on mitochondrial DNA differences, a much more ...
... gastric fluid acidification to expel helminths. IL-5 from CD4 T cells will activate eosinophils to attack helminths. IL-10 ... IL-10 from CD4 T cells activate NK cells' ADCC to apoptose virus-infected cells and to induce host as well as viral DNA ... Th9 cells are claimed to be an IL9 (interleukin 9)-producing T cell subset focused on defending helminth infections.[20] ... These cells undergo abortive infection with HIV.[23] Cell death is triggered when the host cell detects HIV foreign DNA ...
Toxocariasis: A helminth infection of humans caused by the dog or cat roundworm, Toxocara canis or Toxocara cati ... Initial studies of incomplete DNA sequences[29] suggested the existence of five clades:[30] ... An analysis of the mitochondrial DNA suggests that the following groupings are valid[35] ...
Docile moose may suffer from brain worm, a helminth which drills holes through the brain in its search for a suitable place to ... Ludt, C. J.; Schroeder, W.; Rottmann, O.; Kuehn, R. (2004). "Mitochondrial DNA phylogeography of red deer (Cervus elaphus)". ... Randi, E.; Mucci, N.; Claro-Hergueta, F.; Bonnet, A.; Douzery, E. J. P. (2001). "A mitochondrial DNA control region phylogeny ... "Mitochondrial DNA phylogeography of red deer (Cervus elaphus)". Molecular Phylogenetics and Evolution. 31 (3): 1064-83. doi: ...
Helminths of Nyala, Tragelaphus angasii, in Natal". The Onderstepoort Journal of Veterinary Research. 58 (4): 275-80. PMID ... Mitochondrial DNA analysis revealed the presence of a unique haplotype in individuals from each location. The conclusions were ... A study of the helminths from 77 nyalas from four game reserves in Natal revealed the presence of ten nematode species and four ... Willows-Munro, S.; Robinson, T. J.; Matthee, C. A. (June 2005). "Utility of nuclear DNA intron markers at lower taxonomic ...
DNA evidence from sub-fossil remains of teeth and jawbones of Neolithic pigs shows that the first domestic pigs in Europe had ... Young animals are vulnerable to helminths like Metastrongylus, which are consumed by boars through earthworms and cause death ... BBC News, "Pig DNA reveals farming history" 4 September 2007. The report concerns an article in the journal PNAS ... "Ancient DNA, pig domestication, and the spread of the Neolithic into Europe" (PDF). Proceedings of the National Academy of ...
Morgan, E.R.; Shaikenov, B.; Torgerson, P.R.; Medley, G.F.; Milner-Gulland, E.J. (2005). "Helminths of saiga antelopes in ... "Mitochondrial DNA variation and population structure of the Critically Endangered saiga antelope Saiga tatarica". Oryx. 40 ... "Ancient DNA sequences point to a large loss of mitochondrial genetic diversity in the saiga antelope (Saiga tatarica) since ...
Helminths (worms)[edit]. Helminth organisms (also called helminths or intestinal worms) include: Tapeworms[edit]. Common name ... DNA virus. HBV (B). RNA virus. CBV. HAV (A). HCV (C). HDV (D). HEV (E). HGV (G). ... DNA virus. HBV Hepatocellular carcinoma. HPV Cervical cancer. Anal cancer. Penile cancer. Vulvar cancer. Vaginal cancer. ... DNA virus. Human polyomavirus 2 Progressive multifocal leukoencephalopathy. RNA virus. MeV Subacute sclerosing panencephalitis ...
The presence of helminth parasites in the gastrointestinal tract of the little brown bat is most common in the spring and fall ... Based on a 2007 study using mitochondrial and nuclear DNA, it is part of a Nearctic clade of mouse-eared bats. Its sister taxon ... inferred from mitochondrial and nuclear DNA genes". Molecular Phylogenetics and Evolution. 43 (1): 32-48. doi:10.1016/j.ympev. ...
... found in DNA upstream of each constant region gene (except in the δ-chain). The DNA strand is broken by the activity of a ... helminths, allergens). ... "Roles of nonhomologous DNA end joining, V(D)J recombination, ... RAG proteins play an important role with V(D)J recombination in cutting DNA at a particular region.[39] Without the presence of ... Casali P, Zan H (2004). "Class switching and Myc translocation: how does DNA break?". Nat. Immunol. 5 (11): 1101-1103. PMID ...
Multicellular organisms and intestinal worms (helminths) such as Schistosoma spp., Wuchereria bancrofti, Necator americanus ( ... Recent developments in using DNA to identify separate species and to investigate the relationship between groups at various ... discovered the only known helminth that, without treatment, is capable of indefinitely reproducing within a host and causes the ...
Transformation involves the transfer of DNA from a donor cell to a recipient cell and the integration of the donor DNA into the ... Some eukaryotic organisms, including a number of protozoa and helminths, are human parasites (i.e., they cause various ... This expels the pathogen's DNA, making it incapable of producing proteins and causing the bacteria to die. A class of bacteria ...
Reduced DNA damage; ameliorates the hepatic and intestinal damage. Reduced worm and egg count. [21]. ... Decreased cytokine-induced chromosomal aberrations and DNA damage. Significant reduction in. chromosomal aberrations. [20]. ...
DNA samples isolated from pinch biopsies were PCR amplified for sequencing through a validated protocol [31]. The V4 region of ... 2011) Probiotic helminth administration in relapsing-remitting multiple sclerosis: a phase 1 study. Mult Scler 17: 743-754. [ ... 9. Allen JE, Maizels RM (2011) Diversity and dialogue in immunity to helminths. Nat Rev Immunol 11: 375-388. [PubMed] ... Indeed, there is evidence that experimental helminth treatment can ameliorate symptoms in IBD patients [2], [3] and in mice [4] ...
DNA, Helminth. Grant support. *F32-GM089007/GM/NIGMS NIH HHS/United States ...
Antigens, Helminth / genetics * Bile Acids and Salts / physiology * China * DNA, Helminth / genetics* ...
DNA, Complementary * Enzyme Activation * Enzyme Precursors / metabolism * HeLa Cells * Helminth Proteins / metabolism ...
There is evidence that helminth infections skew the host immune system of human and animals to T-helper type 2 (Th2) and induce ... Experimental: DNA and protein 4mg DNA and 600 mcg protein formulated with Alum co-administration (IM) at Month 0, 1 and 6 in ... Biological: DNA DNA co-administered with protein at month 0, 1 and 6 ... Biological: DNA DNA co-administered with protein at month 0, 1 and 6 ...
Buy a discounted Hardcover of Helminth Zoonoses online from Australias leading online bookstore. ... Booktopia has Helminth Zoonoses, CURRENT TOPICS IN VETERINARY MEDICINE AND ANIMAL SCIENCE by S. Geerts. ... Echinococcus granulosus from Kenya using cloned DNA markers.- Kinetics of molecular transfer across the tegument of ... Although the life cycles of most helminths of zoonotic importance are well known, there are still major gaps in our knowledge ...
We used an unmatched case-control design to calculate the odds ratios for helminth infection in children with at least one ... Weighted odds ratio stratified by age group for helminth infection in cases versus controls was 0.50 (95% confidence interval ... At the end, all pupils submitted a stool sample for microscopic investigation for helminth eggs. ... Helminth infection rate in cases was 21 of 115 (18.3%) compared with 456 of 1,327 (34.4%) in controls. ...
A Comparison with a Flotation-Based Technique and an Investigation of Variability in DNA Detection Naomi E. Clarke, Stacey ... Quantitative Evaluation of a Handheld Light Microscope for Field Diagnosis of Soil-Transmitted Helminth Infection Isaac I. ... A total of 91 Kato-Katz thick smears were examined by experienced microscopists and helminth eggs were counted and expressed as ... Appropriate diagnostic techniques are crucial to global soil-transmitted helminth (STH) control efforts. The recommended Kato- ...
While each helminth species completes a distinct life cycle within the host, several helminths incite significant lung disease ... While each helminth species completes a distinct life-cycle within the host, several helminths incite significant lung disease ... The impact of helminths on the pulmonary immune response involves a sophisticated orchestration and activation of the host ... The impact of helminths on the pulmonary immune response involves a sophisticated orchestration and activation of the host ...
... we recommend that these aspects of the protocol should be adopted by any stool sampling and DNA extraction protocol for dow … ... The choice of DNA extraction kit significantly affects the outcome of NAATs. Given the clear benefit of bead beating and our ... Isothermal diagnostic assays for the detection of soil-transmitted helminths based on the SmartAmp2 method. Rashwan N, Diawara ... ethanol and extracted by four DNA extraction protocols. The DNA extraction protocols include the QIAamp DNA Stool Mini kit ...
0 (DNA, Helminth); 0 (DNA, Ribosomal Spacer); 0 (RNA, Ribosomal, 18S); EC 1.9.3.1 (Electron Transport Complex IV). ... DNA de Helmintos/qu mica. DNA de Helmintos/isolamento & purifica o. DNA Espa ador Riboss mico/qu mica. Dictyocaulus/anatomia & ... DNA Mitocondrial/gen tica. Europa (Continente). Fran a. Genoma Mitocondrial. Filogenia. An lise de Sequ ncia de DNA. ... found in a nearby cave and containing large amounts of Bovinae DNA. We show that the Bovinae mitochondrial DNA sequences from ...
0 (DNA, Helminth); 0 (DNA, Ribosomal). [Em] M s de entrada:. 1706. ... DNA de Helmintos/qu mica. DNA de Helmintos/gen tica. DNA Riboss mico/qu mica. DNA Riboss mico/gen tica. Feminino. Pulm o/ ... DNA de Protozo rio/gen tica. Didelphis/parasitologia. RNA Riboss mico 18S/gen tica. Trypanosomatina/gen tica. ... An lise de Sequ ncia de DNA. Am rica do Sul. Infec es por Strongylida/diagn stico. Infec es por Strongylida/parasitologia. ...
DNA-Binding Proteins / biosynthesis, genetics, physiology*. Gene Expression Regulation / physiology. Genes, Helminth / genetics ... 0/Caenorhabditis elegans Proteins; 0/DAF-2 protein, C elegans; 0/DNA-Binding Proteins; 0/Hypoxia-Inducible Factor 1; 0/Metals, ... 8267607 - Transcription factors dna-binding activity in rat thymocytes undergoing apoptosis after.... 9121557 - Abnormal ...
Interestingly, both authors have reported that L. sporogenes reduced chromosomal aberrations and DNA damage induced by ... Other Helminths. In addition to the aforementioned helminth infections, other roundworms, like hookworms and Strongyloides, are ... Hence, helminth parasites are of significant concern to public health and food safety. Furthermore, helminths also infect a ... 2. Trends of Probiotics against Helminth Zoonosis. Zoonotic helminth infections are still remaining a challenge posing a ...
Ciprofloxaxin is an example of which type of DNA gyrase inhibitor?. Which family of helminth is always hermaphroditic?. ...
... we screened an additional 370 DNA extracts for these helminths only. Of these 370 samples, 2 DNA extracts yielded positive ... Of these fecal DNA extracts, a negative inhibition and extraction control excluded 37 samples. We tested 224 DNA extracts for ... We found no samples to contain helminth eggs or larvae. Sufficient sample for DNA extraction was available for 631 (99.5%) ... We stored DNA extracts at −80°C and sent them to the CDC for real-time PCR analysis. At CDC, each sample was initially tested ...
Some of the protocols require DNA sequence data, whereas others were developed independently of whole-genome sequence data. ... FISH Mapping for Helminth Genome Hirohisa Hirai, Yuriko Hirai. Pages 379-394 ... Random Mutagenesis Strategies for Construction of Large and Diverse Clone Libraries of Mutated DNA Fragments ...
Real-time RT-PCR was performed using SYBR Green PCR Master Mix for 38 cycles on an Opticon ΙΙ DNA engine (MJ Research). β-Actin ... Helminth stimulated macrophages are an important source of TNF-α in coinfected mice. We have recently observed that helminth ... 1⇓). Helminth infection alone also induces increased colonic macrophage accumulation (Fig. 1⇓C). More significantly, helminth ... helminth infection and helminth infection-induced-Th2 cytokine responses have been suggested to affect macrophages by inducing ...
Time-saving lesson video on Helminths & Immunity with clear explanations and tons of step-by-step examples. Start learning ... DNA & RNA. 11:46. Motility. 11:24. Plasma Membrane. 16:11. Antibody & Antigen Recognition. 15:50. ... helminth influence on immunity, types of chronic tissue helminth infection, pathogen co-existence and immunity, and helminths ... She discusses the immune system, autoimmunity and helminth infection, coevolution of helminths and immunity, the localized ...
Helminth eggs are about 40 microns or larger in size. Helminths in Drinking water in developing countries often is scarce and ... Viruses are genetic material (RNA or DNA) surrounded by a protein protective coating. Viruses are considerably smaller than ... Helminths Schistosomiasis Schistosoma Venous circulation of human; urine, feces, dogs, cats, pigs, cattle, horses, field mice, ... The most common microbes found in water fall into four categories: bacteria, protozoa, viruses, and helminths. A few examples ...
Elevated eosinophils often indicative of a helminth. infestation. - Eosinophil mitochondrial DNA and proteins form. structure ... Attack parasitic helminths by attaching to their surface. - Secrete toxins that weaken or kill the helminth. - ...
Helminth infection suppresses T-cell immune response to HIV-DNA-based vaccine in mice. Vaccine 24:5211-9. ... "Phase I Dose-Escalation Clinical Trial to Evaluate the Safety and Immunogenicity of the EP HIV-1090 DNA Vaccine in Healthy, HIV ...
Saccone, C., Gissi, C., Reyes, A., Larizza, A., Sbisà, E. and Pesole, G. (2002). Mitochodrial DNA in metazoa: degree of freedom ... Rausch, R. L. and Hilliard, D. K. (1970). Studies on the helminth fauna of Alaska. XLIX. The occurrence of Diphyllobothrium ... Nakao, M., Yokoyama, N., Sako, Y., Fukunaga, M. and Ito, A. (2002). The complete mitochondrial DNA sequence of the cestode ... Brown, W. M., Prager, E. M., Wang, A. and Wilson, A. C. (1982). Mitochondrial DNA sequences of primates: tempo and mode of ...
Ontology (2) GO (2) DNA sequence (1) EMBL (1) Protein domain (3) InterPro (2) Pfam (1) All databases (6) Download RDF ... RG Helminth Genomes Consortium; RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313,WBParaSite:HPLM ... RN [3] {ECO:0000313,EMBL:VDO23390.1, ECO:0000313,Proteomes:UP000268014} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC ... DNA. DR WBParaSite; HPLM_0000451401-mRNA-1; HPLM_0000451401-mRNA-1; HPLM_0000451401. DR Proteomes; UP000038042; Genome Assembly ...
Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts. ... Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel. ... Ginkgo biloba L. Leaf Extract Protects HepG2 Cells Against Paraquat-Induced Oxidative DNA Damage. ...
Presentation] Helminths suppress streptozotocin-induced diabetes via STAT6- and IL-10-independent mechanisms2014. *. Author(s) ... Journal Article] Use of cell-free circulating schistosome DNA in serum, urine, semen, and saliva to monitor a case of ... By comparison of multiple helminth species, we tried to find essential factors for anti-inflammatory properties of parasitic ... The findings obtained in our research partially elucidated the anti-inflammatory effects of helminths and would contribute to ...
Which helminths are known to sit in the gut, consume energy and cause weight loss? ... What is the only helminth that can complete its life cycle in a human host? ...
Helminths (cestodes, trematodes, nematodes, and acanthocephalans). *Preservation in 70-90% ethanol or glycerol-ethanol (10% ... glycerol in 70% ethanol) is preferred as this allows for DNA extraction and molecular identification, if deemed necessary ... as examination of different life stages and sexes of helminths/arthropods may assist in accurate diagnosis. If you would like ...
Residual DNA/RNA deriving from cultured cells - Total amount of DNA: 1.7-3.7 μg/dose, the 80% of which was human (Human fetal ... Other microbial contaminants - Proteobacteria, nematode-helminth. *Processing residues of genetic material - NO ... Residual DNA/RNA deriving from cultured cells - Total amount of DNA: 1.7-3.7 μg/dose, the 80% of which was human (Human fetal ... Considering that, for example, the flu vaccine contains approximately 15mcg of antigen per strain, the DNA/RNA levels ...
  • The secondary objective of the trial is to evaluate the effect of S. mansoni infection on the immunogenicity of the combination of DNA-HIV-PT123 and AIDSVAX® B/E vaccine regimen. (clinicaltrials.gov)
  • The proposed vaccine trial will generate safety, tolerability and immunogenicity data of a vaccination regimen with simultaneous administration of a candidate HIV DNA vaccine (DNA-HIV-PT123) and a gp120 protein vaccine (AIDSVAX®B/E). This will be the first HIV vaccine trial to prospectively evaluate the impact of the S. mansoni infection on safety and immune responses to HIV vaccines. (clinicaltrials.gov)
  • The relationship between intestinal helminth infection and susceptibility to malaria remains unclear. (ajtmh.org)
  • We used an unmatched case-control design to calculate the odds ratios for helminth infection in children with at least one attack of malaria (cases) and children with no malaria episodes during the study (controls). (ajtmh.org)
  • Helminth infection rate in cases was 21 of 115 (18.3%) compared with 456 of 1,327 (34.4%) in controls. (ajtmh.org)
  • The negative association between helminth infection and malaria may be of importance in the design of deworming programs. (ajtmh.org)
  • The Newton Nm1 microscope may be a useful tool for the detection and quantification of soil-transmitted helminth infection in clinical, epidemiologic, and public health settings. (ajtmh.org)
  • Further delineation of the convoluted interface between helminth infection and the pulmonary host immune responses is critical to the development of novel therapeutics that are critically needed to prevent the significant global morbidity caused by these parasites. (frontiersin.org)
  • Host organs such as the lungs are a frequent target of helminth infection. (frontiersin.org)
  • PCR performed on 224 fecal samples for all soil-transmitted helminths and on 370 samples for only Necator americanus and Strongyloides stercoralis identified 1 S. stercoralis infection. (cdc.gov)
  • Nowadays, one of the most prevalent zoonotic diseases is infection with helminth parasites, which infect about one-third of the human population worldwide. (hindawi.com)
  • Infection with helminths usually tends to be chronic rather than acute infection, although there can be acute manifestations after initial infection in naive hosts. (hindawi.com)
  • To dissect the mechanisms by which helminths modulate the host's response to enteric bacteria and bacteria-mediated intestinal inflammation, we have recently established a coinfection model and shown that coinfection with the helminth Heligmosomoides polygyrus exacerbates colitis induced by infection with the Gram-negative bacterial pathogen Citrobacter rodentium . (jimmunol.org)
  • These results demonstrate that helminth infection can impair host protection against concurrent enteric bacterial infection and promote bacteria-induced intestinal injury through a mechanism that involves the induction of alternatively activated macrophages. (jimmunol.org)
  • Helminth infection has been shown to dampen Th1 reactions to other infections ( 1 , 2 , 3 , 4 ). (jimmunol.org)
  • She discusses the immune system, autoimmunity and helminth infection, coevolution of helminths and immunity, the localized impact, immune modulation, response, helminth influence on immunity, types of chronic tissue helminth infection, pathogen co-existence and immunity, and helminths and autoimmunity in mice. (educator.com)
  • Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts. (nih.gov)
  • Fasciolosis is an important parasitic zoonosis considered the most important helminth infection of ruminants in tropical countries. (degruyter.com)
  • In the present study, a simple PCR test for the detection of A. sidemi infection in European bison based on DNA from third stage infective larvae (L3) has been optimized. (biomedcentral.com)
  • It is possible to detect A. sidemi infection in European bison using DNA from L3. (biomedcentral.com)
  • Helminth infection suppresses T-cell immune response to HIV-DNA-based vaccine in mice. (harvard.edu)
  • We find that after helminth infection, or immunization with helminth antigens, reactive lymphoid organs of 4get IL-4/GFP reporter mice contain populations of IL-4/GFP-expressing CD4 + T cells that display the TFH markers CXCR5, PD-1, and ICOS. (rupress.org)
  • Th2 cells and their associated cytokines IL-4 and IL-13 play a crucial role in promoting host survival during infection with parasitic helminths that have tissue-dwelling phases ( 8 ), and they can mediate expulsion of intestinal helminths ( 9 ). (rupress.org)
  • This helminth infection was recorded in Norht America dated up to 10,000 years B.P. (Moore et al. (bioline.org.br)
  • show that intestinal helminth infection, caused by parasitic worms, protects IBD-susceptible mice from developing the disease. (sciencemag.org)
  • The greatest incidence of each of these diseases is in sub-Saharan Africa, where helminth infection is endemic ( 1 , 2 ). (asm.org)
  • To evaluate the influence of helminth infection on vaccines, we can evaluate the ability to induce vaccine-specific immune responses in helminth-infected recipients or in recipients who have been treated with immune-biasing helminth antigens ( 11 - 13 ). (asm.org)
  • Specifically, helminth infection has been shown to suppress immune responses to a Th1-type vaccine and impair the expansion of pathogen-specific cytotoxic CD8 + T cell (cytotoxic T lymphocyte [CTL]) responses ( 18 - 20 ). (asm.org)
  • showing suppression of tetanus-specific responses in schistosome-infected children ( 8 ), helminth infection may pose a significant problem for the development of virus-specific CTL and Th1-type HIV-1 vaccines ( 7 , 8 , 11 ). (asm.org)
  • One method to overcome helminth-induced vaccine suppression is to identify vaccine vectors that are capable of producing vaccine-specific responses irrespective of helminth infection. (asm.org)
  • Below this level, helminth infection in the community will progressively decline, ultimately to zero. (thefreedictionary.com)
  • Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. (wikipedia.org)
  • Many DNA viruses elicit host DDRs during infection and some viruses require the DDR for efficient replication. (prolekare.cz)
  • Given that E2F activity is often deregulated by infection with DNA viruses, these observations raise the possibility that an E2F1-mediated mechanism of DDR activation may be conserved among DNA viruses. (prolekare.cz)
  • In Ethiopia, the prevalence and distribution of helminth infection varies by different exposing risk factors. (readbyqxmd.com)
  • Schistosome infection and soil-transmitted helminths (STHs) are major public health problems in many developing countries where they contribute to the suffering of populations living in poor settings. (readbyqxmd.com)
  • A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection. (elifesciences.org)
  • Helminths are multicellular parasitic organisms belonging to a diverse taxonomic group of metazoans that compromise the phylum Platyhelminths, known as flatworms, including cestodes and trematodes, and Nematoda, known as roundworms, including Ascaris , hookworm, whipworms, filarial parasites, and others. (frontiersin.org)
  • Therefore, the aim of the present review is to raise attention and to summarize recent findings on probiotics research against helminth parasites of zoonotic significance. (hindawi.com)
  • Hence, helminth parasites are of significant concern to public health and food safety. (hindawi.com)
  • The Parasites of Homo sapiens - an Annotaed Checklist of the Protozoa, Helminths and Arthropods for which we are Home , 2nd Edn. (cambridge.org)
  • Considering the profound immune activation and dysregulation induced by helminth parasites, the overlapping geographic distributions of helminth and bacterial infections, and the potential to modulate bacteria-associated intestinal inflammation, we have recently established a coinfection model system to facilitate detailed analysis of the combined effects of helminth and bacterial pathogens on host responses. (jimmunol.org)
  • Owing to the control of insect vector populations, the safe disposal of human excrement, and the availability of efficacious drugs, helminth parasites have been largely eradicated as a public health concern in developed countries. (asm.org)
  • One consequence of this geopolitical segregation is that most of the world's pharmaceutical industries do not support active research and development programs on helminth parasites that cause human disease. (asm.org)
  • Many helminth parasites are long-lived and cause chronic infections. (asm.org)
  • Amongst these parasites, soil-transmitted helminths (STHs), including Ancylostoma duodenale and Necator americanus (hookworms), Ascaris sp. (biomedcentral.com)
  • Th2 response plays a major role in defense against extracellular parasites, particularly against gastrointestinal helminth infections. (mcponline.org)
  • Santos, C.P. & Gibson, D.I. 2015: Checklist of the Helminth Parasites of South American Bats. (wikimedia.org)
  • A checklist of the helminth parasites of sympatric rodents from two Mayan villages in Yucatán, México. (wikimedia.org)
  • Helminth parasites of Australasian monotremes and marsupials. (wikimedia.org)
  • Helminth parasites ensure their survival by regulating host immunity through mechanisms that dampen inflammation. (asm.org)
  • Hunter-gatherers were found to be less infected by helminths, whereas agricultural groups showed comparatively higher prevalences of intestinal parasites in archaeological sites in the United States (Reinhard 1992). (bioline.org.br)
  • We provide the first evidence in Mola species of the occurrence of larval forms of two helminth parasites typically known from the Atlantic Ocean, suggesting a potential long-distance migration of the examined host fish. (frontiersin.org)
  • Drug resistance in helminth parasites has incurred several difficulties to livestock industry and ranked among the top public health concerns. (bioportfolio.com)
  • Helminth parasites bias immune responses to the CD4 + Th2 type and can be immune suppressive ( 3 - 10 ). (asm.org)
  • A total of 120 gastro-intestinal tracts and 960 faecal samples were examined to assess the prevalence and seasonal changes in the gastro-intestinal helminth parasites of Red Sokoto (maradi) goats slaughtered at Ibadan between May 1991 and April 1992. (semanticscholar.org)
  • As baby grows bigger the more likely to be infested with intestinal parasites, worms helminths. (bucurestitu.ro)
  • Her research interests are focused primarily on the evolution, epidemiology, behaviour and control of helminth and protozoan parasites of humans and animals. (rvc.ac.uk)
  • There is evidence that helminth infections skew the host immune system of human and animals to T-helper type 2 (Th2) and induce immunosuppression. (clinicaltrials.gov)
  • Furthermore, the influence of helminth infections on the development of protective antibody responses remains unclear. (clinicaltrials.gov)
  • We evaluated the Newton Nm1, a commercially available handheld light microscope and compared it with conventional light microscopy for the diagnosis of soil-transmitted helminth infections. (ajtmh.org)
  • Together, the impact of helminth infections contributes to more than 12 million disability adjusted life years (DALYS), a measure of significant global mortality and morbidity ( 2 ). (frontiersin.org)
  • For some human helminth infections, such as paragonomiasis, the adult stage of the parasite takes up its final residence in the lung ( 3 ). (frontiersin.org)
  • This paper is a comprehensive, concise, and an up to date review about probiotics effect and mechanisms against helminth infections of zoonotic importance. (hindawi.com)
  • However, the effects of these beneficial microorganisms in helminth infections remain largely unexplored. (hindawi.com)
  • State-of-the-art research on beneficial effects of bacteria on helminth infections and their proposed mechanisms of action is thoroughly discussed. (hindawi.com)
  • Mental and growth stunting among children is also a big problem with helminth infections. (hindawi.com)
  • The distribution of several pathogenic helminth infections coincides geographically with many devastating microbial diseases, including enteric bacterial infections. (jimmunol.org)
  • The major importance of helminth infections includes not only the direct pathogenic effect of the worms but also the modulatory role of the parasite on the host immune system, which may alter the response to other Ags or pathogens and cause additional immunopathology. (jimmunol.org)
  • The immune response that develops during this time often proceeds to cause pathologic changes that in many helminth infections are the primary cause of disease. (asm.org)
  • Treat Helminth infections first, or concurrently? (cpnhelp.org)
  • Parasitic helminth infections cause production losses in farm animals worldwide. (biomedcentral.com)
  • Importantly, Th2 responses are associated with the development of strong antibody responses, particularly IgG1 and IgE, which in certain helminth infections are implicated in resistance to reinfection ( 10 - 12 ). (rupress.org)
  • Infections of Intestinal Helminth at Two Species of Field Mice, Apodemus agrarius and A. Peninsulae, in Gangwondo and Chungcheongnam-do, Korea. (medindia.net)
  • Parasitic infections and resource economy of Danish Iron Age settlement through ancient DNA sequencing. (medindia.net)
  • I am very interested in how common and persistent infections (endemic), like gut helminths, may alter the likelihood of epidemic diseases emerging and spreading in populations. (cardiff.ac.uk)
  • 2012. Co-infections of malaria and soil-transmitted helminths in localities with different levels of urbanisation in the Mount Cameroon region [Poster] . (cardiff.ac.uk)
  • In addition, blood and stool samples were analysed for the presence of Plasmodium, filarial roundworm, intestinal protozoan, and helminth infections. (readbyqxmd.com)
  • Helminth co-infections are common in sub-Saharan Africa. (readbyqxmd.com)
  • Building on a previous community-based study on human cysticercosis in Malanga village, we investigated co-infections with Taenia solium, soil-transmitted helminths (STHs) and Schistosoma spp and associated risk factors in a random subsample of 330 participants. (readbyqxmd.com)
  • The most common microbes found in water fall into four categories: bacteria, protozoa, viruses, and helminths. (waterencyclopedia.com)
  • While studies have shown fungal communities to be significant modulators of human health, information on the prevalence of taxa such as protozoa and helminths has been limited to a small number of species for which targeted molecular diagnostics are available. (biomedcentral.com)
  • Sequencing of these regions revealed protozoa in all stool samples from children with SAM and helminths in most, including several eukaryotes previously implicated in malnutrition and diarrheal disease. (biomedcentral.com)
  • In spite of the availability of modern broad-spectrum anthelmintic drugs, the prevention and control of helminth zoonoses remain a challenge to human and veterinary parasitologists and to physicians and veterina- rians working on the field. (booktopia.com.au)
  • Prevention and control of helminth parasitic zoonosis is possible, from a simple application of hygiene and sanitation to regular deworming with anthelmintic drugs. (hindawi.com)
  • While each helminth species completes a distinct life cycle within the host, several helminths incite significant lung disease. (frontiersin.org)
  • Furthermore, helminths also infect a wide range of animal species and bring about direct and indirect economic losses to livestock production [ 3 ]. (hindawi.com)
  • By comparison of multiple helminth species, we tried to find essential factors for anti-inflammatory properties of parasitic helminths. (nii.ac.jp)
  • Species-specific amplification by PCR of ribosomal DNA from some equine strongyles. (springer.com)
  • A species specific satellite DNA of Drosophila guanche , Z. (springer.com)
  • Burrows, P.R., 1988, The differentiation of Globodera pallida from G. rostochiensis using species-specific DNA probes, Nematologica (Abstract. (springer.com)
  • The species-specific primers generated a 406 bp fragment, and A. sidemi DNA could be detected at concentrations of 0.1 pg/μl. (biomedcentral.com)
  • 1992). Helminth species that normally hatch out of their eggs and leave feces are trapped by drying, providing records of hookworm (Araújo et al. (bioline.org.br)
  • For species identification, helminths are either cleared in lactophenol (nematodes and small acanthocephalans) or stained (trematodes, cestodes, and large acanthocephalans) using Harris' hematoxylin or Semichon's carmine. (jove.com)
  • Helminths are keyed to species by examining different structures ( e.g . male spicules in nematodes or the rostellum in cestodes). (jove.com)
  • Taxonomic identification, especially to species, can be very time consuming and might require the submission of specimens to an expert or DNA analysis. (jove.com)
  • The use of helminth species as biological tags for the sunfish is also discussed. (frontiersin.org)
  • Sublethal antimicrobial exposure can trigger DNA damage and genomic instability across the diversity of microbial pathogens, including bacterial and fungal species. (prolekare.cz)
  • Microbial species contend with numerous environmental perturbations that can lead to DNA damage, including exposure to direct damage by ultraviolet (UV) light, or damage by chemical compounds. (prolekare.cz)
  • In this section, we discuss general mechanisms by which antimicrobials can damage DNA, and strategies employed by microbial species to repair this damage. (prolekare.cz)
  • Murine studies suggest that the presence of some species of intestinal helminths is associated with changes in host microbiota composition and diversity. (asm.org)
  • Cellular DNA is constantly bombarded by insults from both intrinsic sources, such as reactive oxygen species, and extrinsic sources, like genotoxic chemicals. (prolekare.cz)
  • Blouin M (2002) Molecular prospecting for cryptic species of nematodes: mitochondrial DNA versus internal transcribed spacer. (springer.com)
  • DNA sequence data were used to examine phylogenetic relationships between six species of economically important Tetranychidae mites:Eotetranychus carpini (Oudemans),E. pruni (Reck),Tetranychus pacificus McGregor,T. mcdanieli McGregor,T. turkestani Ugarov & Nikolski andT. (semanticscholar.org)
  • Helminths are parasitic worms, an evolutionarily ancient and diverse group of metazoan organisms, which include cestode tapeworms, nematode roundworms, and trematode flukes. (hindawi.com)
  • Faye Rodgers is a bioinformatician working on helminths â parasitic worms that cause a range of diseases. (rio-negocios.com)
  • ATM activation leads to the phosphorylation of numerous proteins that ultimately signal cell cycle arrest and DNA repair and/or apoptosis. (prolekare.cz)
  • This inherent ability of helminths to induce Th2 responses has led to interest in them from both the perspective of elucidation of the underlying mechanisms that lead to Th2 response development and in terms of understanding Th2 response function. (asm.org)
  • helminths and antigens derived from them inherently induce Th2-polarized responses ( 13 ). (rupress.org)
  • We will look at specific examples by which antimicrobial treatment, through DNA damage and cellular responses, can induce genetic perturbations ranging from small nucleotide mutationsto gross chromosomal rearrangements [ 1 , 4 ]. (prolekare.cz)
  • Even low doses of antimicrobials can directly or indirectly induce DNA damage and alterations ( Fig. 1 ). (prolekare.cz)
  • As pathogens in the body, helminths induce an immune response. (wikipedia.org)
  • Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms that infect at least one billion people globally living in extreme poverty. (frontiersin.org)
  • The four major types of helminths are "roundworms" (nematodes), "thorny-headed worms" (acanthocephalans), "flukes" (trematodes), and "tapeworms" (cestodes). (jove.com)
  • Blouin M (1998) Mitochondrial DNA, diversity in nematodes. (springer.com)
  • Consistent with a relationship between Th2 and TFH cells, IL-4 protein production, reported by expression of huCD2 in IL-4 dual reporter (4get/KN2) mice, was a robust marker of TFH cells in LNs responding to helminth antigens. (rupress.org)
  • Though both DNA-HIV-PT123 and AIDSVAX®B/E and the combination of the two vaccines have been evaluated in humans and have shown to be safe and well tolerated, this is the first time the combination regimen is being evaluated in HIV-1 uninfected African populations with and without S. mansoni. (clinicaltrials.gov)
  • In humans, T helper cells and eosinophils respond to helminth infestation. (wikipedia.org)
  • A DNA extraction and preservation protocol that yields sufficient and qualitative DNA is pivotal for the success of any nucleic acid amplification test (NAAT), but it still poses a challenge for soil-transmitted helminths (STHs), including Ascaris lumbricoides, Trichuris trichiura and the two hookworms (Necator americanus and Ancylostoma duodenale). (cdc.gov)
  • Ascaris and hookworm were the most common helminths detected, with prevalence rates of 14 (12.2%) and 6 (5.2%) among cases compared with 333 (25.1%) and 132 (10.0%) in controls, respectively ( P = 0.001). (ajtmh.org)
  • With improved sanitation and economic development, soil-transmitted helminths (STH), including the hookworms Ascaris lumbricoides and Trichuris trichiura , were presumed to have been eliminated. (cdc.gov)
  • Viruses are genetic material (RNA or DNA) surrounded by a protein protective coating. (waterencyclopedia.com)
  • Some of the protocols require DNA sequence data, whereas others were developed independently of whole-genome sequence data. (springer.com)
  • Antimicrobial-induced ROS, such as hydroxyl radicals, damage DNA through the formation of DNA strand breaks, and the incorporation of oxidized guanine residues into the genome [ 13 , 14 ]. (prolekare.cz)
  • Repair of damaged DNA is critical for microbial survival, yet certain DNA damage repair pathways may introduce mutations into the genome. (prolekare.cz)
  • All living organisms are continually exposed to agents that damage their DNA, which threatens the integrity of their genome. (asmscience.org)
  • Therefore, there is a potential that helminth infected populations may not generate the desired immune responses to vaccines designed to drive Th1-type and cytotoxic T-cell responses. (clinicaltrials.gov)
  • This ability to attenuate damaging Th1-driven inflammatory responses in the host ( 5 , 6 , 7 , 8 ) has prompted the evaluation of helminth as a therapeutic agent for the treatment of some immune-mediated disorders, including certain types of inflammatory bowel diseases ( 9 ). (jimmunol.org)
  • Although Mbd2 is widely expressed in gastrointestinal immune cells and is implicated in regulating intestinal cancer, anti-helminth responses and colonic inflammation, the Mbd2-expressing cell types that control these responses are incompletely defined. (exeter.ac.uk)
  • While vaccine development has advanced from attenuated organism to recombinant protein or use of plasmid DNA, the development of new adjuvants that safely increase immune responses has not kept pace. (asm.org)
  • demonstrated that mice infected with Schistosoma mansoni were unable to mount significant HIV-1 vaccine-specific T cell responses to a plasmid DNA HIV-1 vaccine, even when the vaccine was enhanced ( 11 ). (asm.org)
  • We also explore downstream cellular responses to DNA damage, including DNA repair. (prolekare.cz)
  • In bacteria, DNA damage may lead to up-regulation of an SOS response, error-prone translesion DNA synthesis, or other stress responses that result in mutations including single nucleotide polymorphisms (SNPs) and the movement of mobile genetic elements. (prolekare.cz)
  • In fungi, treatment with antifungals can lead to DNA damage, resulting in homologous recombination and loss of heterozygosity (LOH), or other cellular stress responses, leading to unequal chromosomal segregation during mitosis and aneuploidy. (prolekare.cz)
  • DNA damage resulting from intrinsic or extrinsic sources activates DNA damage responses (DDRs) centered on protein kinase signaling cascades. (prolekare.cz)
  • Cell signalling systems, such as adaptive and oxidative stress responses, although not DNA repair pathways per se, are nevertheless essential to counteract DNA damage and mutagenesis. (asmscience.org)
  • A total of 15 protein sequences with high homology to known eukaryotic TIMPs were predicted from the complement of sequence data available for parasitic helminths and subjected to in-depth bioinformatic analyses. (biomedcentral.com)
  • The phosphorylated STAT6 dimer translocates to the nucleus, binds to TTCN 4 GAA-containing DNA sequences, and activates IL-4-responsive genes ( 10 , 11 , 18 , 19 ). (mcponline.org)
  • Nadler, S.A. 1998: Phylogenetic relationships of the Acanthocephala inferred from 18S ribosomal DNA sequences. (wikimedia.org)
  • DNA sequences dated thousand years ago, recovered from archaeological material, means the possibility to study parasite-host relationship coevolution through time. (bioline.org.br)
  • Phylogeography of skinks ( Chalcides ) in the Canary Islands inferred from mitochondrial DNA sequences. (vertebradosibericos.org)
  • Berenit Mendoza for the preparation of specimens for SEM, and Laura Márquez for support obtaining DNA sequences. (springer.com)
  • Sublethal doses of antimicrobial agents can directly or indirectly damage DNA in bacteria and fungi. (prolekare.cz)
  • Although the life cycles of most helminths of zoonotic importance are well known, there are still major gaps in our knowledge especially in the fields of epidemiology, diagnosis and treat- ment The International Colloquium on Helminth Zoonoses held at the Institute of Tropical Medicine, Antwerp, 11-12 December 1986, laid emphasis on more recent advances made in the control and epidemiology of these zoonotic diseases. (booktopia.com.au)
  • In helminth epidemiology, the critical mean wormload in a community, below which the helminth mating frequency is too low to maintain reproduction. (thefreedictionary.com)
  • Parasitic helminths, or worms, comprise a diverse group of metazoan organisms that infect billions of people and their domesticated animals worldwide ( 22 ). (asm.org)
  • The impact of helminths on the pulmonary immune response involves a sophisticated orchestration and activation of the host innate and adaptive immune cells. (frontiersin.org)
  • The results showed clear differences in DNA concentration across both DNA extraction kits, which varied across both STHs. (cdc.gov)
  • Soil-transmitted helminths (STHs) are widespread in underdeveloped countries. (readbyqxmd.com)
  • Real time PCR assays were used to detect DNA of soil-transmitted helminths (STHs), T. (readbyqxmd.com)
  • DNA sequencing techniques have also confirmed the presence of commensal meiofauna in the GI tract that may be important in promoting health and disease.1 Certain types of meiofauna (e.g. helminths and Blastocystis ) are thought to protect against IBD by suppressing inflammation, and others believe that increased fungal diversity may contribute to GI diseases, including IBD. (scienceblog.com)
  • Laser microirradiation experiments revealed that the H3K27me3 mark, but not the KDM6B protein, colocalise with γH2AX-positive sites of DNA damage in differentiating ESCs. (biologists.org)
  • Second, antimicrobials may interact with their target protein in a manner that directly induces DNA damage. (prolekare.cz)
  • Antiprotozoan drugs include those that affect protein synthesis, are metabolites, and inhibit DNA synthesis in the organism. (coursehero.com)
  • DNA damage resulting from these challenge produces a complex protein kinase signaling cascade that promotes repair of the damaged DNA and activates cell cycle checkpoints or apoptosis [1] . (prolekare.cz)
  • A central mediator of certain DNA damage response (DDR) pathways is the ataxia telangiectasia mutated (ATM) protein kinase [2] . (prolekare.cz)
  • Their genomes are circular, double-stranded DNA that is associated with much less protein than eukaryotic genomes. (gopetsamerica.com)
  • The whipworm Trichuris suis is a widespread helminth parasite of pigs. (asm.org)
  • We found no samples to contain helminth eggs or larvae. (cdc.gov)
  • In medical terms, intestinal helminth helminths tratament eficient are larvae eggs them. (bucurestitu.ro)
  • A new DNA microarray tool for the examination of S. stercoralis biology has been developed and provides new and valuable insights regarding differences between infective and noninfective S. stercoralis larvae. (pubmedcentralcanada.ca)
  • We developed the first DNA microarray for this parasite and used it to compare infective third-stage larvae (L3i) with non-infective first stage larvae (L1). (pubmedcentralcanada.ca)
  • Intermediate Host An organism that harbors the larval or asexual stage of helminth or protozoan. (coursehero.com)
  • In parasitic helminths, such as hookworms, TIMPs have been proposed to play key roles in the host-parasite interplay, including invasion of and establishment in the vertebrate animal hosts. (biomedcentral.com)
  • A detailed understanding of the molecular biology of parasitic helminths, and in particular of the structure and function of key genes and gene products playing essential roles in host-parasite interactions, could provide a basis for the design of novel therapeutics. (biomedcentral.com)
  • No parasite DNA was found in any of the sputa of our patient group. (biomedcentral.com)
  • Helminths tratament eficient seeds are a popular and highly effective treatment against intestinal worms, helping to treat Giardia, tapeworms and pinworms. (bucurestitu.ro)
  • Let's talk about helminth worms, for instance, or enzymes with crab claws to unhinge bacteria, and secrets in dirt. (rutgers.edu)
  • In this lesson, our instructor Catherine Carpenter gives an introduction on helminths and immunity. (educator.com)
  • Prevalence and seasonal changes in the gastro-intestinal helminths of Nigerian goats. (semanticscholar.org)
  • Preservation in 70-90% ethanol or glycerol-ethanol (10% glycerol in 70% ethanol) is preferred as this allows for DNA extraction and molecular identification, if deemed necessary following morphologic examination. (cdc.gov)
  • Finally, deep sequencing of bacterial 16S rRNA revealed changes to the composition of microbial communities attached to the intestinal mucosa following helminth treatment. (pubmedcentralcanada.ca)
  • 2. Microbial stool analysis using DNA identification: Gastrointestinal microbiota imbalance (dysbiosis) is a common and significant finding in IBD. (townsendletter.com)
  • Microbial Stool Analysis Using DNA Identification. (townsendletter.com)
  • Here we investigate general mechanisms by which antimicrobials can damage microbial DNA. (prolekare.cz)
  • Despite zoonotic helminth diseases being still a challenge to the public health and the agriculture industries globally, they were still neglected in both human and veterinary medicine. (hindawi.com)
  • Consequently, the use of beneficial microorganisms, probiotics, is becoming interesting for its prophylactic or therapeutic application against several diseases including helminths. (hindawi.com)
  • The findings obtained in our research partially elucidated the anti-inflammatory effects of helminths and would contribute to development of lowly pathogenic helminth-based therapy on inflammatory diseases in the future. (nii.ac.jp)
  • Currently, knowledge of helminth TIMPs is limited to a small number of studies on canine hookworms, whereas no information is available on the occurrence of TIMPs in other parasitic helminths causing neglected diseases. (biomedcentral.com)
  • The ability to repair DNA damage and maintain genomic integrity is fundamental to survival of both bacterial and fungal pathogens. (prolekare.cz)
  • Antimicrobial-induced DNA damage in bacterial and fungal pathogens. (prolekare.cz)
  • These findings suggest that helminth treatment in primates can ameliorate colitis by restoring mucosal barrier functions and reducing overall bacterial attachment, and also by altering the communities of attached bacteria. (pubmedcentralcanada.ca)
  • For bacteria, the SOS response is the global response to DNA damage. (prolekare.cz)
  • At the end, all pupils submitted a stool sample for microscopic investigation for helminth eggs. (ajtmh.org)
  • A total of 91 Kato-Katz thick smears were examined by experienced microscopists and helminth eggs were counted and expressed as eggs per gram of stool (EPG). (ajtmh.org)
  • In the present study, using our in vivo coinfection model as well as in vitro approaches, we test the hypothesis that the phenotypic and functional alterations in macrophages induced by the helminth-driven T cell response may contribute to the observed alterations in the response to C. rodentium . (jimmunol.org)
  • If multiple whole specimens are in question, please submit all available specimens, as examination of different life stages and sexes of helminths/arthropods may assist in accurate diagnosis. (cdc.gov)
  • Journal Article] Use of cell-free circulating schistosome DNA in serum, urine, semen, and saliva to monitor a case of refractory imported schistosomiasis haematobia. (nii.ac.jp)
  • Characterization of the hydatid disease organism, Echinococcus granulosus from Kenya using cloned DNA markers. (booktopia.com.au)
  • Eukaryotic Cells A cell having DNA inside a distinct membrane-enclosed nucleus. (coursehero.com)
  • These interact in a complex way to contribute towards both health and the development of disease - interactions that are only now being elucidated thanks to the application of advanced DNA sequencing technology in this field. (scienceblog.com)
  • Despite repeated negative stool examinations for any intestinal pathogen, the diagnosis was established by the detection of F. hepatica DNA in stool and pus aspirate samples. (bvsalud.org)
  • They require some expertise on recognizing the different organs and being able to differentiate helminths from other tissue debris or gut contents. (jove.com)
  • DNA analysis of the individual's gastrointestinal microbiota along with food allergy testing provided individualized guidance for interventions. (townsendletter.com)
  • Helminth induced morbidity is largely due to the direct impact of the helminth on host tissues and indirectly from the host inflammatory response reflecting the complex helminth-host interface. (frontiersin.org)
  • Type material of Acanthocephala, Nematoda and other non-helminths phyla (Cnidaria, Annelida, and Arthropoda) housed in the Helminthological Collection of the Oswaldo Cruz Institute/ FIOCRUZ (CHIOC), Rio de Janeiro, Brazil, from 1979 to 2016. (wikimedia.org)
  • He was a member of the HVTN protocol development team for a "Phase I Dose-Escalation Clinical Trial to Evaluate the Safety and Immunogenicity of the EP HIV-1090 DNA Vaccine in Healthy, HIV-1-Uninfected Adult Participants. (harvard.edu)
  • It is alarming to see the quantity of DNA/RNA amounts found in the MMRV vaccine. (ageofautism.com)
  • Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: en. (biomedsearch.com)
  • We observe that inhibition of the H3K27 demethylase activity induces DNA damage along with activation of the DNA damage response (DDR) and cell death in differentiating but not in undifferentiated ESCs. (biologists.org)
  • An example of this is the antibiotic bleomycin, which binds DNA and directly induces double-strand breaks by a mechanism that is not fully understood [ 5 ]. (prolekare.cz)