Compounds with two triple bonds. Some of them are CYTOTOXINS.
Rhodium. A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh. (Dorland, 28th ed)
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Effects of a lipoxygenase inhibitor, panaxynol, on vascular contraction induced by angiotensin II. (1/35)

We investigated whether a lipoxygenase inhibitor, panaxynol, affected the vascular contraction induced by angiotensin (Ang) II and the mean arterial pressure in spontaneously hypertensive rats (SHR). Panaxynol suppressed dose-dependently the contractile responses induced by 30 nM Ang II in isolated intact and endothelial cell-denuded aorta in the hamster. IC50 values in the intact and endothelial cell-denuded aorta were 23 and 20 microM, respectively. In SHR, the mean arterial pressure after injection of 30 and 60 mg/kg panaxynol was reduced, and the maximum hypotensive values were 23 and 48 mmHg, respectively. Thus, lipoxygenase products may affect the renin-angiotensin system.  (+info)

Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. (2/35)

Cerebral microvascular endothelial cells (CMVEC) form tubes when cocultured with astrocytes (AS). Therefore, it appears that AS may be important in mediating angiogenesis in the brain. We hypothesized that AS modulate CMVEC tube formation by releasing a soluble factor. Thymidine incorporation in cultured CMVEC increased 305% when incubated with 50% conditioned AS medium for 24 h [control: 52,755 +/- 4,838 counts per minute (cpm) per well, conditioned 161,082 +/- 12,099 cpm/well, n = 8]. Because our laboratory has previously shown that AS can produce epoxyeicosatrienoic acids (EETs), which are known mitogens, we investigated whether release of EETs by AS is responsible for tube formation in the CMVEC-AS coculture. AS were seeded on Lab-Tek slides, CMVEC were seeded on the AS the next day, and cultures were allowed to progress for another 5 days with and without cytochrome P-450 epoxygenase blockade by 17-octadecynoic acid (17-ODYA). Tube formation in cocultures receiving 17-ODYA was significantly inhibited compared with control (93.8%). These data suggest that tube formation requires the release of EETs by AS.  (+info)

Chemical constituents from the colombian medicinal plant Niphogeton ternata. (3/35)

Two coumarins and one polyacetylene, 5-0-(3-chloro-2-hydroxy-3-methylbutyl)-8-methoxypsoralen (1), 2',3'-dihydro-jatamansin (2), and 10-chloro-1-heptadecene-4,6-diyne-3,8,9-triol (3), along with 15 known compounds (4-18), were isolated from the methanol extract of Niphogeton ternata. Their structures were elucidated by spectroscopy.  (+info)

Synthesis of panax acetylenes: chiral syntheses of acetylpanaxydol, PQ-3 and panaxydiol. (4/35)

Acetylpanaxydol (1-Ac), PQ-3 (2) and panaxydiol (3) and their optical isomers were synthesized from L-(+)-diethyl tartrate. The absolute configurations of 1-Ac, 2 and 3 were determined to be 1-Ac (3R,9R,10S), 2 (9R,10S) and 3 (3R,10S), respectively, by comparisons of their optical rotations and the NMR data of their MTPA esters with those of natural products.  (+info)

Effects of the polyacetylene capillin on human tumour cell lines. (5/35)

We investigated the effects of capillin, a constituent of Artemisia monosperma, on four human tumour cell lines: colon carcinoma H729, pancreatic carcinoma MIA PaCa-2, epidermoid carcinoma of the larynx HEp-2 and lung carcinoma A549. Cells were treated with capillin to examine both the anti-proliferative and pro-apoptotic effects, as well as the molecular mechanism underlying these effects. Changes in cell proliferation, membrane permeability, macromolecular synthesis, glutathione (GSH), cell cycle and programmed cell death were evaluated. Capillin (1microM-10microM) inhibited cell proliferation and decreased macromolecular synthesis simultaneously, in a dose- and time-dependent manner. Co-incubation with L-buthionine sulfoximine (L-BSO) augmented the efficacy of capillin. Capillin modulated GSH levels, accumulated cells in the S+G2/M-phase of the cell cycle and induced cell death and DNA fragmentation, as indicated by flow cytometry, fluorescence microscopy and DNA fragmentation assay. These findings suggest that capillin has cytotoxic activity and can induce apoptosis in human tumour cell lines.  (+info)

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. (6/35)

We describe the synthesis and properties of a small molecule mimic of Smac, a pro-apoptotic protein that functions by relieving inhibitor-of-apoptosis protein (IAP)-mediated suppression of caspase activity. The compound binds to X chromosome- encoded IAP (XIAP), cellular IAP 1 (cIAP-1), and cellular IAP 2 (cIAP-2) and synergizes with both tumor necrosis factor alpha (TNFalpha) and TNF-related apoptosis-inducing ligand (TRAIL) to potently induce caspase activation and apoptosis in human cancer cells. The molecule has allowed a temporal, unbiased evaluation of the roles that IAP proteins play during signaling from TRAIL and TNF receptors. The compound is also a lead structure for the development of IAP antagonists potentially useful as therapy for cancer and inflammatory diseases.  (+info)

Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes. (7/35)

The effects of falcarindiol on the expression of inducible nitric oxide synthase (iNOS) induced by lipopolysaccharide/interferon-gamma (LPS/IFN-gamma) in rat primary astrocytes were investigated. The molecular mechanisms underlying falcarindiol that confers its effect on iNOS expression were also elucidated. Falcarindiol abrogated the LPS/IFN-gamma-mediated induction of iNOS by about 80%. Falcarindiol attenuated the induction of iNOS in a concentration-dependent manner. The inhibitory effect of falcarindiol on iNOS induction was attributable to decrease in the protein content and the mRNA level of iNOS. Treatment with 50 microM of falcarindiol for 30 min decreased LPS/IFN-gamma-induced nuclear factor-kappaB (NF-kappaB) activation by 32%. Treatment with 50 microM of falcarindiol for 60 min diminished the LPS/IFN-gamma-mediated activation of IkappaB kinase-alpha (IKK-alpha) and IKK-beta by 28.2 and 29.7%, respectively. Falcarindiol modulated the nuclear translocation of signal transducer and activator of transcription 1 (Stat1) in a time-dependent manner. Falcarindiol (50 microM) decreased the tyrosine phosphorylation of janus kinase 1 (JAK1) by 84.8% at 5 min. Falcarindiol also abrogated the tyrosine phoshorylation of JAK2 by 82.3% at 10 min.The present study demonstrates that falcarindiol attenuated the activation of IKK and JAK contributing to the blockade of activation of NF-kappaB and Stat1, thereby leading to the suppression of iNOS expression.  (+info)

Electrolyte effects on bilayer tubule formation by a diacetylenic phospholipid. (8/35)

A general effect by dissolved electrolytes to destabilize the curvature of bilayer tubules prepared from the diacetylenic phospholipid, 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine is not found. This observation discounts the role of an electrostatic interaction between polarization charges on the edges of a ferroelectric bilayer as a means by which the cylindrical curvature may be stabilized in these structures (de Gennes, P. G. 1987. C. R. Acad. Sci. Paris. 304:259-263). The solution-mediated ionic interactions of electrolytes with this phospholipid appear not to influence significantly the relative stability of the crystalline state of the tubule, but at high levels of a few salts, may affect the nucleation and growth of the crystalline bilayer. Curvature of the bilayer in these tubular structures apparently derives from an interaction that is not very sensitive to the presence of electrolytes. Cylindrical curvature may alternatively arise from a bending force within the bilayer that is intrinsic to the anisotropic packing of the lipid molecules (Helfrich, W., and J. Prost. 1988. Phys. Rev. A38:3065-3068; Chappell, J. S., and P. Yager. 1991. Chem. Phys. Lipids. In press), and may therefore be largely determined by the packing interactions within the hydrophobic region of the tubular bilayer.  (+info)

Diynes are organic compounds that contain two carbon-carbon triple bonds in their molecular structure. The general chemical formula for diynes is R-C≡C-C≡C-R, where R can be a hydrogen atom or any organic group. Diynes are important building blocks in organic synthesis and have been used to create complex molecules, nanomaterials, and pharmaceuticals. They are also of interest in materials science due to their unique electronic properties and potential applications in optoelectronics and photonics.

I'm sorry for any confusion, but "Rhodium" is not a medical term. It is a chemical element with the symbol Rh and atomic number 45. It is a rare, silvery-white, hard, corrosion-resistant, and chemically inert transition metal. It is found in small quantities in platinum or nickel ores along with some other rare metals.

It's primarily used in industrial applications, such as being a key component in catalytic converters in automobiles, which helps to reduce harmful emissions. It's also used in jewelry, electronics, and scientific instruments due to its properties of resistance to corrosion and heat.

If you have any medical terms or concepts that you would like me to explain, please let me know!

Cyclization is a chemical process that involves forming a cyclic structure or ring-shaped molecule from a linear or open-chain compound. In the context of medicinal chemistry and drug design, cyclization reactions are often used to synthesize complex molecules, including drugs, by creating rings or fused ring systems within the molecule's structure.

Cyclization can occur through various mechanisms, such as intramolecular nucleophilic substitution, electrophilic addition, or radical reactions. The resulting cyclized compounds may exhibit different chemical and biological properties compared to their linear precursors, making them valuable targets for drug discovery and development.

In some cases, the cyclization process can lead to the formation of stereocenters within the molecule, which can impact its three-dimensional shape and how it interacts with biological targets. Therefore, controlling the stereochemistry during cyclization reactions is crucial in medicinal chemistry to optimize the desired biological activity.

Overall, cyclization plays a significant role in the design and synthesis of many pharmaceutical compounds, enabling the creation of complex structures that can interact specifically with biological targets for therapeutic purposes.

Catalysis is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst, which remains unchanged at the end of the reaction. A catalyst lowers the activation energy required for the reaction to occur, thereby allowing the reaction to proceed more quickly and efficiently. This can be particularly important in biological systems, where enzymes act as catalysts to speed up metabolic reactions that are essential for life.

Molecular structure, in the context of biochemistry and molecular biology, refers to the arrangement and organization of atoms and chemical bonds within a molecule. It describes the three-dimensional layout of the constituent elements, including their spatial relationships, bond lengths, and angles. Understanding molecular structure is crucial for elucidating the functions and reactivities of biological macromolecules such as proteins, nucleic acids, lipids, and carbohydrates. Various experimental techniques, like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM), are employed to determine molecular structures at atomic resolution, providing valuable insights into their biological roles and potential therapeutic targets.

Related reactions occur with diynes. Furthermore, titanocene can catalyze C-C bond metathesis to form asymmetric diynes. Many ... and Zirconocenes Do with Diynes and Polyynes?". Chem. Rev. 33 (2): 119-129. doi:10.1021/ar9900109. PMID 10673320. Rosenthal, ...
Addition of a 1,5-diyne with an alkyne produces a benzocyclobutene, a strained structure that can then be induced to undergo ... Hsieh, J.-C.; Cheng, C.-H. (2005). "Nickel-Catalyzed Cocyclotrimerization of Arynes with Diynes; A Novel Method for Synthesis ... Sato, Y.; Tamura, T.; Mori, M. (2004). "Arylnaphthalene lignans through Pd-Catalyzed 2+2+2 cocyclization of arynes and diynes: ... Cyclisation carried out with a diyne and a separate alkyne affords greater control.[clarification needed] Using commercially ...
... (penta-1,4-diyne) is a chemical compound belonging to the alkynes. The compound is the structural isomer to 1,3- ... doi:10.1016/0040-4020(69)80026-8. H. D. Verkruijsse; M. Hasselaar (1974). "An Improved Synthesis of 1,4-Diynes". Synthesis. 4 ( ... Although long-chain and more complex 1,4-diynes had been synthesized successfully before, synthesis approaches starting from ...
One strategy to remedy this problem employs certain diynes: The selected reaction conditions also minimize the amount formed of ... Jen-Chieh Hsieh and Chien-Hong Cheng (2005). "Nickel-catalyzed cocyclotrimerization of arynes with diynes; a novel method for ... Cycloadditions of Terminal Diynes for the Synthesis of Substituted Cyclooctatetraenes Paul A. Wender and Justin P. Christy J. ... positions and reacts with a di-yne such as 1,7-octadiyne along with a nickel(II) bromide / zinc catalyst system (NiBr2 bis( ...
... is the organic compound with the formula (C6H5C2)2. It is a common diyne. It is the product of the coupling ... 3-Diynes". The Journal of Organic Chemistry. 70 (2): 703-706. doi:10.1021/jo048428u. PMID 15651824. Mills, O. S.; Shaw, B. W. ( ... Novel Syntheses of Conjugate Diynes and Disubstituted Ethynes". The Journal of Organic Chemistry. 65 (6): 1780-1787. doi: ...
2004). "How Large is the Conjugative Stabilization of Diynes?". J. Am. Chem. Soc. 126 (46): 15036-7. doi:10.1021/ja046432h. ...
... and Zirconocenes Do with Diynes and Polyynes?". Accounts of Chemical Research. 33 (2): 119-129. doi:10.1021/ar9900109. ISSN ...
T. K. Lane, B. R. D'Souza, J. Louie "2-Aminopyridines from Iron-Catalyzed Cycloaddition of Diynes and Cyanamides" J. Org. Chem ... She would use carbon dioxide mixed with different diynes to prepare different 2-pyrones. The simple reaction for the formation ... Taking all these chemical factors into account, the Ni/NHC catalyst can effectively couple diynes and nitriles to create ... "Efficient Nickel-Catalyzed [2 2 2] Cycloaddition of CO2and Diynes." Journal of the American Chemical Society 124.51 (2002): ...
"The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins". Journal of ...
2000). "What Do Titano- and Zirconocenes Do with Diynes and Polyynes?". Chemical Reviews. 33 (2): 119-129. doi:10.1021/ ...
2000). "What Do Titano- and Zirconocenes Do with Diynes and Polyynes?". Chemical Reviews. 33 (2): 119-129. doi:10.1021/ ...
... and other diynes with electron withdrawing substituents. The ideal arrangement of diynes in the solid state is a repeat ... This was achieved by exposing crystals of 1,6-bishydroxy hexa-2,4-diyne to UV light. Polymerization was assumed to occur ... Typically, this must occur in the solid state, because many diynes undergo both 1,2 and 1,4 polymerization in solution - such ... Synthesis of polydiacetylenes occurs through topochemical polymerization of 1,3-diynes. ...
2000). "What Do Titano- and Zirconocenes Do with Diynes and Polyynes?". Chemical Reviews. 33 (2): 119-129. doi:10.1021/ ...
Part I. cyclo-Tetradeca-1:3-diyne and Related Compounds". J. Chem. Soc.: 889. doi:10.1039/JR9590000889. Eglinton, G.; McRae, W ... Graham E. Jones, David A. Kendrick, Andrew B. Holmes (1987). "1,4-Bis(trimethylsilyl)buta-1,3-diyne". Organic Syntheses. 65: 52 ... can also form diynes Glaser, Carl (1870). "Untersuchungen über einige Derivate der Zimmtsäure" [Studies on some derivatives of ...
Graham E. Jones, David A. Kendrick, and Andrew B. Holmes (1987). "1,4-Bis(trimethylsilyl)buta-1,3-diyne". Organic Syntheses. 65 ... Trimethylsilylacetylene is a precursor to 1,4-bis(trimethylsilyl)buta-1,3-diyne, a protected form of 1,3-butadiyne. ...
Graham E. Jones, David A. Kendrick, and Andrew B. Holmes (1987). "1,4-Bis(trimethylsilyl)buta-1,3-diyne". Organic Syntheses. 65 ...
Chen, T.-A.; Liu, R.-S. (2011). "Synthesis of Polyaromatic Hydrocarbons from Bis(biaryl)diynes: Large PAHs with Low Clar ...
When the enyne moiety is incorporated into a 10-membered hydrocarbon ring (e.g. cyclodeca-3-ene-1,5-diyne in scheme 2) the ... In 2015 IBM scientists demonstrated that a reversible Masamune-Bergman cyclisation of diyne can be induced by a tip of an ... atomic force microscope (AFM). They also recorded images of individual diyne molecules during this process. When learning about ...
The reaction product is a 1,3-diyne or di-alkyne. The reaction mechanism involves deprotonation by base of the terminal alkyne ...
5-diyne antitumor antibiotic". J. Am. Chem. Soc. 114 (11): 4107-4110. doi:10.1021/ja00037a011. Hensens, O. D.; Giner, J.; ...
Molecules called ene-diynes feature a ring containing an alkene ("ene") between two alkyne groups ("diyne"). These compounds, e ... Diynes and triynes, species with the linkage RC≡C-C≡CR′ and RC≡C-C≡C-C≡CR′ respectively, occur in certain plants (Ichthyothere ... diyne" is used when there are two triple bonds, and so on. The position of unsaturation is indicated by a numerical locant ... Ene-diynes undergo rearrangement via the Bergman cyclization, generating highly reactive radical intermediates that attack DNA ...
The diyne reacts with dibutylstannane to give 1,1-dibutylstannacyclohexa-2,5-diene. The organotin compound undergoes As/Sn ...
... diyne" is used when there are two triple bonds, and so on. The position of unsaturation is indicated by a numerical locant ...
1,4-Diiodobuta-1,3-diyne is light sensitive and explosive if stored out of solution as a dry solid. It will undergo random 1,2 ... Diiodobutadiyne (1,4-diiodobuta-1,3-diyne) is a small molecule related to diacetylene. It is used in the creation of the ...
Chloride Complex as Highly Efficient Catalysts for the Synthesisof Alkynes in Water or in NMP and of Diynes in the Absence of ... 3-Diynes Via Sonogashira Coupling of Vinylidene Chloride Followed by Elimination. Preparation of 1,3-Decadiyne", Org. Synth., ...
This has led to literally hundreds of synthetic ene-diyne compounds being tested as drugs. For the discovery of the first ... For development of the "Bergman cyclization" of ene-diynes, which was ultimately recognized as a prototype for the first step ...
Novel bicyclization of enynes and diynes promoted by zirconocene derivatives and conversion of zirconabicycles into bicyclic ...
Garrod, B.; Lewis, B.G.; Coxon, D.T. (1978). "Cis-heptadeca-1,9-diene-4,6-diyne-3,8-diol, an antifungal polyacetylene from ... Falcarinol and falcarindiol (cis-heptadeca-1,9-diene-4,6-diyne-3,8-diol) are such compounds. This latter compound shows ...
Falcarinol Garrod, B. (1978). "Cis-heptadeca-1,9-diene-4,6-diyne-3,8-diol, an antifungal polyacetylene from carrot root tissue ...
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chemBlink ,, Chemical Listing ,, 1-Thia-6-selenacyclodeca-3,8-diyne,, Market Analysis Reports ...
The conditions for and products of thermolysis of 4-azahepta-1,6-diyne, (HC≡C-CH2)2NH, have been investigated by microwave, ... N2 - The conditions for and products of thermolysis of 4-azahepta-1,6-diyne, (HC≡C-CH2)2NH, have been investigated by microwave ... AB - The conditions for and products of thermolysis of 4-azahepta-1,6-diyne, (HC≡C-CH2)2NH, have been investigated by microwave ... abstract = "The conditions for and products of thermolysis of 4-azahepta-1,6-diyne, (HC≡C-CH2)2NH, have been investigated by ...
The content of the Repository, unless otherwise specified, is protected with a Creative Commons license: Attribution-Non Commercial-No Derivatives 4.0 ...
The corresponding terminal di-ynes H-C=C-R-C=CH (1b-4b) and their dinuclear platinum(II) complexes trans-[(Et3P)2(Ph)Pt-C=C-R-C ... The corresponding terminal di-ynes H-C=C-R-C=CH (1b-4b) and their dinuclear platinum(II) complexes trans-[(Et3P)2(Ph)Pt-C=C-R-C ... The corresponding terminal di-ynes H-C=C-R-C=CH (1b-4b) and their dinuclear platinum(II) complexes trans-[(Et3P)2(Ph)Pt-C=C-R-C ... The corresponding terminal di-ynes H-C=C-R-C=CH (1b-4b) and their dinuclear platinum(II) complexes trans-[(Et3P)2(Ph)Pt-C=C-R-C ...
This graph shows the total number of publications written about "Diynes" by people in this website by year, and whether "Diynes ... "Diynes" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject Headings) ... Below are the most recent publications written about "Diynes" by people in Profiles. ...
... Kathiravan, Suppan Linnaeus University, ... 3-diynes, themselves a functional class of interest in a range of application areas, to form isoquinolinonesan important ...
Polycyclotrimerization of internal diynes: synthesis of hyperbranched poly(alkenephenylenes). Kaitian Xu, Han Peng, Yi Huang, ... Polycyclotrimerization of internal diynes : synthesis of hyperbranched poly(alkenephenylenes). In: American Chemical Society, ... Polycyclotrimerization of internal diynes: synthesis of hyperbranched poly(alkenephenylenes). / Xu, Kaitian; Peng, Han; Huang, ... Polycyclotrimerization of internal diynes: synthesis of hyperbranched poly(alkenephenylenes). American Chemical Society, ...
Copper-catalyzed intermolecular formal (5 + 1) annulation of 1,5-diynes with 1,2,5-oxadiazoles One-carbon insertion into N-O ... Here, copper-catalyzed intermolecular formal (5 + 1) annulation of 1,5-diynes with 1,2,5-oxadiazoles is shown to facilitate one ...
Related reactions occur with diynes. Furthermore, titanocene can catalyze C-C bond metathesis to form asymmetric diynes. Many ... and Zirconocenes Do with Diynes and Polyynes?". Chem. Rev. 33 (2): 119-129. doi:10.1021/ar9900109. PMID 10673320. Rosenthal, ...
... cycloalkadienes by ring closing diyne- or enyne-yne metathesis/semi-reduction ... Lacombe, F., Radkowski, K., Seidel, G., & Fürstner, A. (2004). (E)-Cycloalkenes and (E,E)-cycloalkadienes by ring closing diyne ... E)-Cycloalkenes and (E,E)-cycloalkadienes by ring closing diyne- or enyne-yne metathesis/semi-reduction ...
Tahara, Y. K., Matsubara, R., & Shibata, T. (2015). [2+2+2] cycloaddition of sulfanylbenzene-tethered diynes with alkynes for ... Tahara, YK, Matsubara, R & Shibata, T 2015, [2+2+2] cycloaddition of sulfanylbenzene-tethered diynes with alkynes for the ... Dive into the research topics of [2+2+2] cycloaddition of sulfanylbenzene-tethered diynes with alkynes for the synthesis of ... N2 - An intermolecular [2+2+2] cycloaddition of sulfanyl- and sulfonylbenzene-tethered 1,6-diynes with alkynes using rhodium ...
Utilization of a Pt(ii) di-yne chromophore incorporating a 2,2′-bipyridine-5,5′-diyl spacer as a chelate to synthesize a green ... Dive into the research topics of Utilization of a Pt(ii) di-yne chromophore incorporating a 2,2′-bipyridine-5,5′-diyl spacer ...
Shimada, T.; Yamamoto, Y. Carbon-Carbon Bond Cleavage of Diynes through the Hydroamination with Transition Metal Catalysts. J. ...
... which are obtained by the reaction of diynes and a low-valent titanium complex, we anticipated that germole-containing π- ...
... trigger and the importance of gem-diaurated species in the gold-catalyzed hydroarylating-aromatization of arene-diynes. ...
Benzene, 1,1-(3-hexene-1,5-diyne-1,6-diyl)bis- (1 supplier). IUPAC Name: 6-phenylhex-3-en-1,5-diynylbenzene , CAS Registry ... Synonyms: Benzene, 1,1-(3-hexene-1,5-diyne-1,6-diyl)bis[2-methoxy-, AGN-PC-005UEE, CTK3E0705 Molecular Formula: C20H16O2. ... BENZENE, 1,1-(3-HEXENE-1,5-DIYNE-1,6-DIYL)BIS[2-METHOXY- (1 supplier). IUPAC Name: 1-methoxy-2-[6-(2-methoxyphenyl)hex-3-en-1, ... Benzene, 1,1-(3,4-diethynyl-3-hexene-1,5-diyne-1,6-diyl)bis-, (E)- (0 suppliers). 142761-76-0. ...
Diyne-containing PPVs: Solid-state properties and comparison of their photophysical and electrochemical properties with those ...
McDougall, Laura (2020) Design and synthesis of diyne constrained peptides for targeting protein-protein interactions. PhD ...
Titanium-Catalyzed [4+2] and [6+2] Cycloadditions of 1,4-Bis(trimethylsilyl)buta-1,3-diyne. Jan-Willem F. Kaagmana, Marco Repa ... 3-diyne. ChemInform 2010, 28, no. ,https://doi.org/10.1002/chin.199720042, ...
Sakai, Norio; Uchida, Naoki; Konakahara, Takeo: Facile and Selective Synthesis of Propargylic Amines and 1,6-Diynes: One-Pot ...
They show that the polymerizations are performed using a diyne, guanidine HCl, DMSO and O2 in the presence of CuCl, Cs2CO3 and ...
Mo, X.; Letort, A.; Roşca, D.-A.; Higashida, K.; Fürstner, A.: Site‐Selective trans‐Hydrostannation of 1,3‐ and 1,n‐Diynes: ...
Dank eines Softwareupdates des Logitech Harmony Skills für Amazon Alexa werden Sprachbefehle künftig noch einfacher. Nutzer müssen beispielsweise nicht mehr „Alexa, schalte den Fernseher ein mit Harmony" sagen, wenn sie eine Logitech Harmony Hub-basierte Fernbedienung zur Steuerung ihrer Alexa-fähigen Geräte mit ihrer Stimme verwenden. Mit dem neuen Harmony Smart Home Skill kann der Zusatz „mit Harmony" künftig weggelassen werden und Alexa versteht den Befehl trotzdem.. Auch Folgebefehle mit Kontextbezug sind durch das kostenlose Softwareupdate möglich. Nachdem sie beispielsweise ihren Smart TV mit der Logitech Harmony und ihrer Stimme gestartet haben, können Anwender mit einfachen Befehlen fortfahren wie „Alexa, mach lauter" oder "Alexa, schalte auf Kanal 3".. Das kostenlose Softwareupdate optimiert die Kommunikation über den Sprachassistenten von Amazon mit der Logitech Harmony Fernbedienung und ermöglicht es Nutzern und allen Familienmitgliedern, ihr Heimkino und ihre ...
This new reaction starts with aryl diynes and a sulfinate salt under copper-mediated conditions to form a new C-S bond and two ...
... alkyne 34 with the diyne 33 (J. Org. Chem. 2022, 87, 14909. DOI: 10.1021/acs.joc.2c01741). ...
Bicyclization of dienes, enynes, and diynes with Ti(ii) reagent. New developments towards asymmetric synthesis. F. Sato, H. ...
11 alkynes: 1-pentyne, 2-pentyne, pent-1-en-4-yne, (E/Z)-pent-3-en-1-yne, penta-1,2-dien-4-yne, penta-1,4-diyne, penta-1,3- ... diyne, pent-1-en-3-yne, 3-methylbut-1-yne, 2-methylbut-1-en-3-yne. (End). ...
Titanium-Catalyzed [4+2] and [6+2] Cycloadditions of 1,4-Bis(trimethylsilyl)buta-1,3-diyne. 1996, Vol. 61, Issue 12, pp. 1722- ...
How to Make a DIY NES Classic with Raspberry Pi, ASUS Tinker Board, and More. Rather than buying an NES Classic Mini, learn how ... to make a DIY NES Classic with a Raspberry Pi or ASUS Tinker Board running RetroPie, Recalbox, Lakka, Batocera, or Slash TV. ...
  • KAAGMAN J.-W. F., REP M., HORACEK M., SEDMERA P., CEJKA J., VARGA V., MACH K.: ChemInform Abstract: Titanium-Catalyzed (4 + 2) and (6 + 2) Cycloadditions of 1,4-Bis( trimethylsilyl)buta-1,3-diyne. (cas.cz)
  • Can buta-1,3-diyne show conjugation in both the unhybridised p orbitals? (stackexchange.com)
  • ‌52‌ ] Another example is Baeyer's preparation of 1,4-diphenylbuta-1,3-diyne derivatives [ ‌53‌ ] and the synthesis of buta-1,3-diyne and its dicarboxylic acid derivatives, [ ‌54‌ , ‌55‌ ] potassium hexacyanoferrate(III) being the oxidizing agent. (thieme.com)
  • Tahara, YK, Matsubara, R & Shibata, T 2015, ' [2+2+2] cycloaddition of sulfanylbenzene-tethered diynes with alkynes for the synthesis of multi-substituted dibenzothiophene derivatives ', Heterocycles , vol. 90, no. 2, pp. 1094-1110. (elsevierpure.com)
  • Site‐Selective trans‐Hydrostannation of 1,3‐ and 1,n‐Diynes: Application to the Total Synthesis of Typhonosides E and F, and a Fluorinated Cerebroside Analogue. (mpg.de)
  • The C-H activation/1,3-diyne strategy: highly selective direct synthesis of diverse bisheterocycles by Rh(III) catalysis. (research.com)
  • An intermolecular [2+2+2] cycloaddition of sulfanyl- and sulfonylbenzene-tethered 1,6-diynes with alkynes using rhodium catalysts gave dibenzothiophene derivatives in moderate to excellent yields. (elsevierpure.com)
  • Furthermore, titanocene can catalyze C-C bond metathesis to form asymmetric diynes. (wikipedia.org)
  • The development of a first row transition metal (cobalt)-based catalyst for the as yet unexplored CH activation-driven reaction of 1,3-diynes, themselves a functional class of interest in a range of application areas, to form isoquinolinonesan important structural motif in a number of biologically active substancesis presented. (diva-portal.org)
  • This new reaction starts with aryl diynes and a sulfinate salt under copper-mediated conditions to form a new C-S bond and two new C-C bonds, which involves the functionalization of an aromatic C-H bond and a formal [3+2] cycloaddition. (uwaterloo.ca)
  • Site-selective trans -Hydrostannation of 1,3- and 1, n -Diynes. (hokudai.ac.jp)
  • It is now used for the preparation of di- and oligoacetylenes, [ ‌49‌ , ‌51‌ ] and is highly suitable for the preparation of symmetrical diynes. (thieme.com)
  • This graph shows the total number of publications written about "Diynes" by people in this website by year, and whether "Diynes" was a major or minor topic of these publications. (wakehealth.edu)
  • Below are the most recent publications written about "Diynes" by people in Profiles. (wakehealth.edu)
  • Ungeheuer, F. Ring-Closing Alkyne Metathesis of 1,3-Diynes: Total Syntheses of Ivorenolide A and B & Studies towards the Total Synthesis of Rhizoxin D/Ringschluss-Alkin-Metathese von 1,3-Diinen: Totalsynthese von Ivorenolide A und B & Studien zur Totalsynthese von Rhizoxin D. Doktorarbeit, Technische Universität Dortmund, Dortmund, 2016. (mpg.de)
  • We have also developed a robust approach for the introduction of diyne linkers into peptides using ligand optimization to promote the Glaser reaction. (aps2022.org)
  • In addition, when performed in an intramolecular context, diyne linkers can be utilized as tethers or as staples to stabilize alpha helical structures. (aps2022.org)
  • Nouvelles perspectives en catalyse énantiosélective par les complexes d'Au(I) à contre-ions phosphates. (viaf.org)