Profile of neurohumoral agents on mesenteric and intestinal blood flow in health and disease. (1/1766)

The mesenteric and intestinal blood flow is organized and regulated to support normal intestinal function, and the regulation of blood flow is, in part, determined by intestinal function itself. In the process of the development and adaptation of the intestinal mucosa for the support of the digestive processes and host defense mechanisms, and the muscle layers for propulsion of foodstuffs, a specialized microvascular architecture has evolved in each tissue layer. Compromised mesenteric and intestinal blood flow, which can be common in the elderly, may lead to devastating clinical consequences. This problem, which can be caused by vasospasm at the microvascular level, can cause intestinal ischaemia to any of the layers of the intestinal wall, and can initiate pathological events which promote significant clinical consequences such as diarrhea, abdominal angina and intestinal infarction. The objective of this review is to provide the reader with some general concepts of the mechanisms by which neurohumoral vasoactive substances influence mesenteric and intestinal arterial blood flow in health and disease with focus on transmural transport processes (absorption and secretion). The complex regulatory mechanisms of extrinsic (sympathetic-parasympathetic and endocrine) and intrinsic (enteric nervous system and humoral endocrine) components are presented. More extensive reviews of platelet function, atherosclerosis, hypertension, diabetes mellitus, the carcinoid syndrome, 5-hydroxytryptamine and nitric oxide regulation of vascular tone are presented in this context. The possible options of pharmacological intervention (e.g. vasodilator agonists and vasoconstrictor antagonists) used for the treatment of abnormal mesenteric and intestinal vascular states are also discussed.  (+info)

A classification of permanent and significant disease for general practitioners. (2/1766)

A new simple classification of diseases seen in general practice is described. The system applies only to permanent conditions or those of continuing medical importance. It is not based on numerals from the International Classification of Disease nor on the College classification but includes a mnemonic. The system is easily adaptable.  (+info)

An innovative approach to reducing medical care utilization and expenditures. (3/1766)

In a retrospective study, we assessed the impact on medical utilization and expenditures of a multicomponent prevention program, the Maharishi Vedic Approach to Health (MVAH). We compared archival data from Blue Cross/Blue Shield Iowa for MVAH (n = 693) with statewide norms for 1985 through 1995 (n = 600,000) and with a demographically matched control group (n = 4,148) for 1990, 1991, 1994, and 1995. We found that the 4-year total medical expenditures per person in the MVAH group were 59% and 57% lower than those in the norm and control groups, respectively; the 11-year mean was 63% lower than the norm. The MVAH group had lower utilization and expenditures across all age groups and for all disease categories. Hospital admission rates in the control group were 11.4 times higher than those in the MVAH group for cardiovascular disease, 3.3 times higher for cancer, and 6.7 times higher for mental health and substance abuse. The greatest savings were seen among MVAH patients older than age 45, who had 88% fewer total patients days compared with control patients. Our results confirm previous research supporting the effectiveness of MVAH for preventing disease. Our evaluation suggests that MVAH can be safely used as a cost-effective treatment regimen in the managed care setting.  (+info)

Improving clinician acceptance and use of computerized documentation of coded diagnosis. (4/1766)

After the Northwest Division of Kaiser Permanente implemented EpicCare, a comprehensive electronic medical record, clinicians were required to directly document orders and diagnoses on this computerized system, a task they found difficult and time consuming. We analyzed the sources of this problem to improve the process and increase its acceptance by clinicians. One problem was the use of the International Classification of Diseases (ICD-9) as our coding scheme, even though ICD-9 is not a complete nomenclature of diseases and using it as such creates difficulties. In addition, the synonym list we used had some inaccurate associations, contributing to clinician frustration. Furthermore, the initial software program contained no adequate mechanism for adding qualifying comments or preferred terminology. We sought to address all these issues. Strategies included adjusting the available coding choices and descriptions and modifying the medical record software. In addition, the software vendor developed a utility that allows clinicians to replace the ICD-9 description with their own preferred terminology while preserving the ICD-9 code. We present an evaluation of this utility.  (+info)

Referrals by general internists and internal medicine trainees in an academic medicine practice. (5/1766)

Patient referral from generalists to specialists is a critical clinic care process that has received relatively little scrutiny, especially in academic settings. This study describes the frequency with which patients enrolled in a prepaid health plan were referred to specialists by general internal medicine faculty members, general internal medicine track residents, and other internal medicine residents; the types of clinicians they were referred to; and the types of diagnoses with which they presented to their primary care physicians. Requested referrals for all 2,113 enrolled prepaid health plan patients during a 1-year period (1992-1993) were identified by computer search of the practice's administrative database. The plan was a full-risk contract without carve-out benefits. We assessed the referral request rate for the practice and the mean referral rate per physician. We also determined the percentage of patients with diagnoses based on the International Classification of Diseases, 9th revision, who were referred to specialists. The practice's referral request rate per 100 patient office visits for all referral types was 19.8. Primary care track residents referred at a higher rate than did nonprimary care track residents (mean 23.7 vs. 12.1; P < .001). The highest referral rate (2.0/100 visits) was to dermatology. Almost as many (1.7/100 visits) referrals were to other "expert" generalists within the practice. The condition most frequently associated with referral to a specialist was depression (42%). Most referrals were associated with common ambulatory care diagnoses that are often considered to be within the scope of generalist practice. To improve medical education about referrals, a better understanding of when and why faculty and trainees refer and don't refer is needed, so that better models for appropriate referral can be developed.  (+info)

Formulary limitations and the elderly: results from the Managed Care Outcomes Project. (6/1766)

OBJECTIVE: To examine whether restrictive formularies are associated with differences in healthcare resource utilization, including number of office visits, prescriptions, and hospitalizations, and whether this association varies by age. STUDY DESIGN: Cross-sectional, longitudinal study. PATIENTS AND METHODS: Patients enrolled in one of six health maintenance organizations in six different states, three in the eastern and three in the western United States, were eligible for the study. Data from between 1309 and 3938 patients were available for analysis for each of the five diseases studied, for a total of 12,997 patients across all study diseases. Healthcare utilization by patients in the study included more than 99,000 office visits, 1000 hospitalizations, and 240,000 prescriptions. We used severity-adjusted prescription counts, prescription costs, office visit counts, and measures of inpatient hospital utilization to assess the effects of formulary limitations. RESULTS: We found positive, significant associations between the independent variable formulary limitations in drug class and the dependent variables measuring resource utilization. These associations were sometimes significantly greater for elderly patients after controlling for severity of illness and other variables. CONCLUSIONS: Common strategies for decreasing drug expenditures may be associated with higher severity-adjusted resource utilization. In specific areas, this association is more pronounced in the elderly.  (+info)

Environmental pathology: new directions and opportunities. (7/1766)

The National Institute of Environmental Health Sciences (NIEHS) supports a number of training programs for predoctoral and postdoctoral (D.V.M., M.D., Ph.D.) fellows in toxicology, epidemiology and biostatistics, and environmental pathology. At the Experimental Biology meeting in April 1997, the American Society of Investigative Pathology (ASIP) sponsored a workshop including directors, trainees, and other interested scientists from several environmental pathology programs in medical and veterinary colleges. This workshop and a related session on "Novel Cell Imaging Techniques for Detection of Cell Injury" revealed advances in molecular and cell imaging approaches as reviewed below that have a wide applicability to toxicologic pathology.  (+info)

History of medicine and concepts of health. (8/1766)

It was not until the exemplary social reform of the 19th century and the introduction of modern health insurance schemes that people started to consider health as some kind of basic right which could be ensured by insurance and doctors, rather than by individual responsibility. The recent explosion of health system costs in countries like Germany has given rise to an unprecedented situation whereby the limited capacities of insurance systems and state organizations are becoming more and more evident. Health economists are now questioning the feasibility of optimal medical treatment for everybody. One consequence of this situation is that people are being forced to recall the old virtue of individual responsibility for one's own physical and mental well-being. This article examines the nature of health from a historical point of view. The point is made that health is not the same thing as a life free from complaints, although this erroneous belief is wide-spread today. Galen himself identified a neutral physical state between health and illness (neutralitas), that could be observed in many people who could not be described as being either healthy or ill. It is necessary to accept this state as part of the natural fate of humankind and to understand that individual responsibility and the demands on society and insurance companies for well-being or absolute freedom from ailments are not one and the same thing.  (+info)

Acute disease An acute disease is a short-lived disease, like the common cold. Chronic disease A chronic disease is one that ... Primary disease A primary disease is a disease that is due to a root cause of illness, as opposed to secondary disease, which ... Secondary disease A secondary disease is a disease that is a sequela or complication of a prior, causal disease, which is ... Progressive disease Progressive disease is a disease whose typical natural course is the worsening of the disease until death, ...
... , named for British surgeon Percivall Pott who first described the symptoms in 1799, also known as Pott disease ... Media related to Pott's disease at Wikimedia Commons Pott's Disease of the Thoracic Spine (CS1 Danish-language sources (da), ... had Pott's disease. Masoaka shiki, japanese poet,author and literary critic had pott's disease Max Blecher's semi- ... has a character with Pott disease. Tuli, Surendar M. (June 22, 2013). "Historical aspects of Pott's disease (spinal ...
The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. The disease is endemic in ... Orf is primarily a disease of sheep and goats although it has been reported as a natural disease in humans, steenbok and ... Viral diseases". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 389. ISBN 978-0-323- ... Sheep and goat diseases, Chordopoxvirinae, Animal viral diseases, Virus-related cutaneous conditions). ...
"Lyme disease rashes and look-alikes". Lyme Disease. Centers for Disease Control and Prevention. 21 December 2018. Archived from ... "Lyme Disease Data and surveillance". Lyme Disease. Centers for Disease Control and Prevention. 5 February 2019. Archived from ... Dogs may also experience chronic joint disease if the disease is left untreated. However, the majority of cases of Lyme disease ... Treatment regimens for Lyme disease range from 14 days in early localized disease, to 14-21 days in early disseminated disease ...
Gastrointestinal diseases (abbrev. GI diseases or GI illnesses) refer to diseases involving the gastrointestinal tract, namely ... Other causes of chronic liver disease are genetic or autoimmune disease, such as hemochromatosis, Wilson's disease, autoimmune ... Liver disease may also be a result of lifestyle factors, such as fatty liver and NASH. Alcoholic liver disease may also develop ... Infectious liver disease may cause a fever. Chronic liver disease may result in a buildup of fluid in the abdomen, yellowing of ...
"Alfalfa Disease Resistance Index - Alforex Seeds". Alforex Seeds. 2019-09-19. Retrieved 2020-11-24. v t e (Articles with short ... In plant science, the disease package of a cultivar is the susceptibility/resistance of that cultivar, in vague overall terms. ... "Choosing Varieties & Hybrids for 2020 - Check Disease Resistance Ratings". Agronomic Crops Network. Ohio State University ... description, Short description matches Wikidata, All stub articles, Plant disease stubs, Plant pathogens and diseases). ...
International Statistical Classification of Diseases (WHO ICD-10) - Diseases of the eye and adnexa (ICD-10 codes H00-H59) ... This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known ... World Health Organization ICD-10 codes: Diseases of the eye and adnexa (H00-H59). [1]. Retrieved 2010-07-28. International ... H02.6) Xanthelasma of eyelid (H03.0*) Parasitic infestation of eyelid in diseases classified elsewhere Dermatitis of eyelid due ...
Blackleg and Other Clostridial Diseases Wikimedia Commons has media related to Blackleg (disease). (All articles with ... The most common causative agent is C. chauvoei, but the disease can also be caused by C. septicum, C. sordelli, and C. novyi. C ... Treatment is generally unrewarding due to the rapid progression of the disease, but penicillin is the drug of choice for ... The acute nature of the disease makes successful treatment difficult, and the efficacy of the commonly used vaccine is disputed ...
Cultural forms are said to involve a cultural belief or myth which plays a role in the genesis and spread of the disease in the ... For example, one physical disorder that causes loss of penile size is Peyronie's disease, where the tunica albuginea develops ... 1997). "The anatomy of the tunica albuginea in the normal penis and Peyronie's disease". The Journal of Urology. 157 (1): 276- ... It is called Disco Rog (Bengali: ডিস্কো রোগ) meaning weird disease or Jhinjhinani Rog (Bengali: ঝিনঝিনানি রোগ) meaning tingling ...
... is most commonly seen in the elderly, and is often described as senile degeneration of the conduction system. One ... Lev's disease is an acquired complete heart block due to idiopathic fibrosis and calcification of the electrical conduction ...
... a degenerative muscle disease also known as Charcot disease or Lou Gehrig's disease Charcot-Marie-Tooth disease, an inherited ... Charcot disease can refer to several diseases named for Jean-Martin Charcot, such as: Amyotrophic lateral sclerosis, ... Eponyms This disambiguation page lists articles associated with the title Charcot disease. If an internal link led you here, ... also known as Charcot joint disease or Charcot arthropathy Spinal osteoarthropathy, a rare abnormal bone growth disorder in ...
2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. James, William D.; Berger, ... Heck's disease, also known as Focal Epithelial Hyperplasia, is an asymptomatic, benign neoplastic condition characterized by ... Heck's disease)". Annali di Stomatologia. 4 (Suppl 2): 43. ISSN 1824-0852. PMC 3860189. PMID 24353818. James, William D.; ... Timothy; Elston, Dirk (2015). Andrews' Diseases of the Skin E-Book: Clinical Dermatology. Elsevier Health Sciences. p. 408. ...
... , also known as Kanzaki disease and alpha-N-acetylgalactosaminidase deficiency, is a rare disease found in ... Infants with Schindler disease tend to die within four years of birth; therefore, treatment for this form of the disease is ... "Schindler Disease". National Organization for Rare Disorders (NORD). Retrieved 2008-11-13. "Kanzaki disease". Genetic and rare ... "Schindler disease". International Advocate for Glycoprotein Storage Diseases. (International Society for Mannosidosis & Related ...
The disease is so rare that the National Organization for Rare Diseases does not even mention Copenhagen disease in their ... The disease is rare, with most cases found in Europe and very few cases reported in North America. Copenhagen disease gets its ... Although this disease does not lead to major neurological symptoms or pain, individuals living with Copenhagen disease may ... The initial stages of this disease closely resemble that of Scheuermann's disease, where "there is a disturbance in the zone of ...
... (SD) is an autosomal recessive lysosomal storage disease characterized by early physical impairment and ... Individuals with Salla disease usually survive into adulthood. Infantile free sialic acid storage disease (ISSD) Online ... Individuals with Salla disease may present with nystagmus as well as hypotonia, and difficulty coordinating voluntary movements ... The mutation causes sialic acid to build up in the cells.[citation needed] The disease is inherited in an autosomal recessive ...
... Discogs. Retrieved on 2010-02-02. Thug Disease at Allmusic Thug Disease at Discogs Thug Disease at Tower Records ... Thug Disease is a compilation presented by American rapper Spice 1. It was released December 17, 2002 on Rap Classics, and also ... "Thug Disease" - 0:18 "Pimps, Players, Hustlers" - 4:15 (Spice 1, Roscoe, Low Lifes & Michelob) "I'm Raw" - 3:06 (1 Da Boy) " ...
... known as Meige disease, has its onset around the time of puberty. Meige disease is also an autosomal dominant disease. It has ... Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease ... Milroy's disease (MD) is a familial disease characterized by lymphedema, commonly in the legs, caused by congenital ... This disease is more common in women and an association with the gene FLT4 has been described. FLT4 codes for VEGFR-3, which is ...
Even though the disease is more common in males, females can still be a carrier of the disease. As the result of a mutation in ... "Menkes Disease". NORD (National Organization for Rare Disorders). Retrieved 2022-10-10. Menkes Disease at eMedicine "Menkes ... "Role of optic microscopy for early diagnosis of Menkes disease". ResearchGate. Retrieved 2015-12-10. "Menkes disease: ... "Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes". J ...
... is a genetic extracellular matrix diseases of the skin characterized by puffy skin. Ehlers-Danlos syndrome List ...
... is the most common disease found in dogs and affects more than 80% of dogs aged three years or older. Its ... Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth ... Several conditions and diseases, including Down syndrome, diabetes, and other diseases that affect one's resistance to ... "Gum Disease". National Institute of Dental and Craniofacial Research. February 2018. Retrieved 13 March 2018. "Gum Disease ...
... and renal disease to help bolster the diagnosis of Kyrle disease. Other underlying diseases that Kyrle disease is observed with ... Kyrle disease is a rare disease unless there is a high count of patients with chronic kidney failure. The disease seems to be ... Kyrle disease is identified as a form of an acquired perforating disease. Other major perforating diseases are elastosis ... Due to the causes of Kyrle disease is unknown, the best way to prevent the disease is to prevent the disorders that are usually ...
Diagnosis of Eales Disease is mainly clinical with exclusion. Diagnosis of this disease can be complete through several ... The diagnosis of Eales disease can be broken down into several stages due to the regular progression of the disease. There are ... The exact cause of this disease is unknown but it appears to affect individuals that are from Asian subcontinents. This disease ... India Eales disease at eMedicine Namperumalsamy, Perumalsamy; Shukla, Dhananjay (2013). "Eales Disease". Retina. pp. 1479-1485 ...
As of June 2022, there is an ongoing outbreak of the disease in Florida. The CDC has identified 26 cases of the disease. Seven ... Centers for Disease Control and Prevention (June 2000). "Prevention and Control of Meningococcal Disease. Recommendations of ... The importance of the carrier state in meningococcal disease is well known. In developed countries the disease transmission ... citing public domain text from the CDC Centers for Disease Control and Prevention (2012). "Ch. 13: Meningococcal Disease". In ...
... (also called Iceland disease or epidemic neuromyasthenia) is the name used for an outbreak of fatigue symptoms ... Chronic fatigue syndrome Blattner R (1956). "Benign myalgic encephalomyelitis (Akureyri disease, Iceland disease)". J. Pediatr ... The disease was first diagnosed as poliomyelitis and the first case was reported on September 25, 1948, in Akureyri. During the ... 1] A disease epidemic in Iceland Simulating PolioMyelitis (Am. J. Epidemiol. (1950) 52 (2): 222-238) The Body: A Guide for ...
The disease was also described by the group of Ehl et al. TRIANGLE disease is caused by loss-of-function mutations in the gene ... The genetic model for this disease is loss-of-function. This means that for people with TRIANGLE disease, the gene TPP2 is ... This disease manifests as recurrent infection, autoimmunity, and neurodevelopmental delay. TRIANGLE disease was first described ... Consequently, individuals without functioning TPPII have severe disease. TRIANGLE disease is inherited in an autosomal ...
"Your Disease" is a song by the band Saliva and is from the band's second album Every Six Seconds. The song was featured in the ... "Your Disease" Official music video on YouTube (Use mdy dates from July 2023, Articles with short description, Short description ...
The disease tends to be gradually progressive. Symptoms such as weakness, ataxia, and dragging of the toes start in the rear ... The disease progresses to the front legs, but the symptoms are less severe. Neck pain is sometimes seen. Symptoms are usually ... Wobbler disease is definitively diagnosed by x-ray, nuclear scintigraphy or bone scan. X-rays will show channel widening or ... Wobbler disease is probably inherited in the Borzoi, Great Dane, Doberman, and Basset Hound. Instability of the vertebrae of ...
... is caused by iron deficiency in babies which are fed exclusively on cow's milk. It is characterized by a tower- ...
Diseases that have been vaccinated against using equine-origin antiserum, resulting in subsequent Theiler's disease, include: ... Theiler's disease is a viral hepatitis that affects horses. It is one of the most common cause of acute hepatitis and liver ... This disease was described in 1919 by Arnold Theiler, a South African veterinary surgeon, after vaccinating horses against ... Measuring levels of virus in the originally infected horses has shown that the disease can become chronic, with some horses ...
"Darier disease , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". Retrieved ... which is why the condition is also referred to as Darier-White disease. Linear Darier disease List of cutaneous conditions ... Diagnosis of Darier disease is often made by the appearance of the skin, family history, or genetic testing for the mutation in ... Darier's disease (DAR) is a rare, inherited skin disorder that presents with multiple greasy, crusting, thick brown bumps that ...
Meningococcal disease can refer to any illness that is caused by Neisseria meningitidis, also known as meningococcus bacteria. ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Meningococcal disease refers to any illness caused by bacteria called Neisseria meningitidis. These illnesses are often severe ... Risk for meningococcal disease when receiving a complement inhibitor. Receiving complement inhibitors such as eculizumab ( ...
Meningococcal disease can be rapidly fatal and should always be viewed as a medical emergency. As soon as disease is suspected ... Centers for Disease Control and Prevention. Public health dispatch: Update: assessment of risk for meningococcal disease ... Although meningococcal disease outbreaks can occur anywhere in the world, they are most common in the African meningitis belt, ... Meningococcal disease generally occurs 1-10 days after exposure and presents as meningitis in ≈50% of cases in the United ...
Get the facts about liver diseases, such as hepatitis, cancer, and cirrhosis. Know your risk and what you can do to prevent ... Inherited diseases, such as hemochromatosis and Wilson disease. Symptoms of liver disease can vary, but they often include ... Glycogen storage disease type III: MedlinePlus Genetics (National Library of Medicine) * Glycogen storage disease type VI: ... Diseases caused by drugs, poisons, or too much alcohol. Examples include fatty liver disease and cirrhosis. ...
Celiac disease (also known as celiac sprue and gluten-sensitive enteropathy) is a prevalent food hypersensitivity disorder of ... The Cribsiders talk about having a low threshold for testing a child for celiac disease, and which tests to order first. ...
Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ... History of genetic disease: the molecular genetics of Huntington disease - a history. Nat Rev Genet. 2005 Oct;6(10):766-73. doi ... Many people with Huntingtons disease develop involuntary jerking or twitching movements known as chorea. As the disease ... that causes Huntingtons disease involves a DNA segment known as a CAG trinucleotide repeat. . This segment is made up of a ...
... and communities fight disease and stay strong; and to protect the publics health. ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... Journal promoting the recognition of new and reemerging infections diseases around the world. ...
See an archive of all alzheimers disease stories published on Intelligencer. ... Südhof about a scandal rocking the world of Alzheimers research and how conceptions of the disease are changing. ... Südhof on how the benefits and limits of Lecanemab have changed his understanding of the disease. ...
Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... Work-Related Respiratory Diseases by NORA Industrial Sectors * Agriculture, Forestry, and Fishing Sector (AFF) ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Chronic obstructive pulmonary disease: Proportionate mortality ratio (PMR) adjusted for age, sex, and race by usual industry, U ...
Human Disease. Geographic Distribution. References. Remarks. References. History. Abbreviations. Information Exchange User ... Centers for Disease Control and Prevention. 1600 Clifton Rd. Atlanta, GA 30333, USA. 800-CDC-INFO (800-232-4636). Contact CDC- ... Centers for Disease Control and Prevention. CDC 24/7: Saving Lives. Protecting People.™ ...
It is an incurable disease with a long and progressive course. ... Alzheimer disease (AD) is an acquired disorder of cognitive and ... Mild Alzheimer disease. The disease begins to affect the cerebral cortex, memory loss continues, and changes in other cognitive ... A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimers disease. The Alzheimers Disease ... encoded search term (Alzheimer Disease) and Alzheimer Disease What to Read Next on Medscape ...
... you may be suffering from an autoimmune disease -- which means your immune system is attacking healthy tissue. ... Life With an Autoimmune Disease If you have general, lingering symptoms, you may be suffering from an autoimmune disease -- ... Rheumatoid arthritis, type I diabetes, psoriasis, alopecia, lupus, thyroid disease, Addisons disease, pernicious anemia, ... Immunoglobulin or antibodies are being used in children with the heart disease called Kawasaki disease, as well as Guillain- ...
Parkinson Disease: UXL Encyclopedia of Diseases and Disorders dictionary. ... PD is not by itself a fatal disease but gets worse over time; in the later stages of the disease, PD may cause complications ... "Unknown: Parkinson Disease ." UXL Encyclopedia of Diseases and Disorders. . Retrieved September 19, 2023 from ... People who have a parent or sibling with Parkinson disease have a slightly increased risk (5 percent) of developing the disease ...
The West Africa Ebola outbreak has led experts to consider what diseases might spark the next major infectious disease crisis. ... The 2011 film Contagion, a fictional portrayal of a global infectious-disease crisis, was based in part on Nipah, which infects ... In addition to beefing up medical capacity and surveillance for new diseases around the world, some specialists argue that the ... Nature canvassed infectious-disease specialists to find out which pathogens they thought would trigger the next global crisis, ...
What do I do if I think I may have Chagas disease?. If you suspect you have Chagas disease, consult your health-care provider. ... The parasite that causes the disease is in the bug feces. The bug generally poops on or near a person while it is feeding on ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... In areas of Latin America where human Chagas disease is an important public health problem, the bugs nest in cracks and holes ...
... information on Alzheimers disease and dementia symptoms, diagnosis, stages, treatment, care and support resources. ... Understanding Alzheimers Disease and Dementia. Alzheimers is the most common form of dementia. It causes problems with memory ... Learn how Alzheimers disease affects a persons memory and other brain functions in our interactive online tour. ... The Alzheimers Association is the leading voice for Alzheimers disease advocacy, fighting for critical Alzheimers research ...
... and common diseases to help prevent disease and improve human health. ... 2014) Respiratory disease in United States farmers. Occup Environ Med, 71:484-491. [Abstract Hoppin JA, Umbach DM, Long S, ... The impact of sex and sex hormones on lung physiology and disease: Lessons from animal studies. Am J Physiol Lung Cell Mol ... The impact of sex and sex hormones on lung physiology and disease: Lessons from animal studies. Am J Physiol Lung Cell Mol ...
GARD Rare Diseases Archive - Page 4 of 404 - National Organization for Rare Disorders ... NORD is not a medical provider or health care facility and thus can neither diagnose any disease or disorder nor endorse or ... Please note that NORD provides this information for the benefit of the rare disease community. ...
... how to prevent disease and immunizations. Checkups look for STDs in sexually active teenagers and inform teens about nutrition ... Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and ... Healthy Living and Disease Prevention. The importance of a healthy lifestyle in disease prevention is widely understood and ... Anyone who wishes to reduce their risk of getting the flu can be vaccinated, however the U.S. Centers for Disease Control and ...
Pain is not disease itself, but is what follows disease. According to my theory, disease is a belief, and where there is no ... Disease of a person is like that of a nation, each is governed by arbitrary laws and the governing of both is alike. Disease is ... HEALTH AND DISEASE. Disease is that part of the mind that can be compared to a wilderness. It is full of erroneous opinions and ... DISEASE 1. What is disease? It is false reasoning. True scientific wisdom is health and happiness. False reasoning is sickness ...
Lyme disease is spreading fast-is a vaccine on the way?. Several vaccines and new treatments are in the works as the ticks that ... "Disease in all of its forms has been with animals since the beginning of their evolution," says Ewan Wolff, a study co-author ... The disease might have then proven fatal for Dolly of its own accord, or its possible that a hungry predator saw the ailing ... A rough disease. Based on observations of living birds with airsacculitis, Woodruff and colleagues think that Dolly must have ...
Theres currently no cure for chronic obstructive pulmonary disease (COPD), but treatment can help slow the progression of the ...
Fellow, Division of Infectious Disease and Pediatrics, Harvard Medical School; Fellow, Division of Infectious Disease, Boston ... news Defining Difficult-to-Treat Inflammatory Bowel Disease * 2001/viewarticle/nhl-car-t-therapy-treats-concurrent-rheumatic- ... news CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease * 2001/viewarticle/aflibercept-biosimilars-show-comparability- ... Judge Dismisses Lyme Disease Lawsuit Against IDSA, Doctors, but the Ordeal Has Left Its Scars ...
Debt and Disease. Despite suffering a near-fatal economic blow from COVID-19, Argentinas government has managed to restructure ...
The Liver Center at UC San Diego Health is the regions leader in the treatment of acute and chronic liver diseases. ... June 26, 2023 . Liver Disease Care Study: Potential New Treatment Identified for Liver Disease. Researchers at the University ... Conditions such as viral hepatitis B or C, fatty liver disease, autoimmune liver disease and hemochromatosis can increase the ... Rohit Loomba Laboratory - fatty liver disease and nonalcoholic steatohepatitis.. *Find a Clinical Trial at UC San Diego Health ...
... shows climbing more than five flights of stairs daily is associated with a lower risk of atherosclerotic cardiovascular disease ... Climbing more than five flights of stairs daily is associated with a reduced risk of atherosclerotic cardiovascular disease ( ... Cases of ASCVD - defined as coronary artery disease (CAD), ischemic stroke, or acute complications - were identified via ... Stair Climbing Tied to Reduced Risk for Heart Disease - Medscape - Oct 19, 2023. ...
People living with Parkinsons disease (PD) can benefit from being physically active, especially when it comes to improving ... The Effects of Physical Activity in Parkinsons Disease: A Review. Journal of Parkinsons Disease, 2016; 6 (4): 685 DOI: ... A comprehensive review published in the Journal of Parkinsons Disease confirms that people living with Parkinsons disease (PD ... Parkinsons disease patients benefit from physical activity. Date:. November 15, 2016. Source:. IOS Press. Summary:. People ...
... prevents the formation of tangles of fibrous protein that are a hallmark of Alzheimers disease. ... Alzheimers disease is a progressive disease that eventually causes severe symptoms. Learn whether Alzheimers is a disability ... The disease is a neurological disorder in which the death of brain cells results in progressive memory loss and cognitive ... In Alzheimers disease, these tau molecules break away from the microtubules and begin to stick together to form threads and, ...
  • Centers for Disease Control and Prevention. (
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (
  • 2 years, meningococcal disease can have nonspecific symptoms. (
  • Symptoms of liver disease can vary, but they often include swelling of the abdomen and legs, bruising easily, changes in the color of your stool and urine, and jaundice , or yellowing of the skin and eyes. (
  • Why Do GI Symptoms Persist in Some Kids With Celiac Disease? (
  • Individuals with the adult-onset form of Huntington's disease usually live about 15 to 20 years after signs and symptoms begin. (
  • People with 36 to 39 CAG repeats may or may not develop the signs and symptoms of Huntington's disease, while people with 40 or more repeats almost always develop the disorder. (
  • The dysfunction and eventual death of neurons in certain areas of the brain underlie the signs and symptoms of Huntington's disease. (
  • If you have general, lingering symptoms, you may be suffering from an autoimmune disease -- which means your immune system is attacking healthy tissue. (
  • Your first symptoms of an autoimmune disease may be general, such as fatigue , low-grade fever, and difficulty concentrating, making autoimmune diseases difficult to diagnose at first. (
  • As the disease develops -- or more than one, as Rose points out -- vague symptoms start to appear, such as joint and muscle pain (very common), general muscle weakness, possible rashes or low-grade fever, trouble concentrating, or weight loss. (
  • It is a progressive disease, meaning that the symptoms get worse over time. (
  • Researchers are not yet certain, however, whether there are additional genes that play a role in the development of PD, and if so, how they interact to produce the symptoms of the disease. (
  • What is known is that the tremor and other muscle-related symptoms of Parkinson disease are caused by damage to a part of the brain called the substantia nigra. (
  • A respiratory disease infecting a sauropod dinosaur nicknamed Dolly would have likely produced symptoms such as coughing, labored breathing, nasal discharge, fever, and weight loss. (
  • There's currently no cure for chronic obstructive pulmonary disease (COPD), but treatment can help slow the progression of the condition and control the symptoms. (
  • What are the signs and symptoms of Pediatric Pancreas Disease? (
  • What Are the Signs & Symptoms of Powassan Virus Disease? (
  • While existing drug treatments help reduce the symptoms of Alzheimer's disease and improve people's quality of life, they neither slow its progression nor cure it. (
  • Ebola diseases symptoms can be sudden. (
  • It can be difficult to clinically distinguish Ebola diseases symptoms from other infectious diseases such as malaria, typhoid fever and meningitis. (
  • A person infected with an Ebolavirus cannot spread the disease until they develop symptoms. (
  • If the current results are replicated in live patients, the skin test could facilitate quicker diagnosis and the ability to start preventive treatments that slow disease progression before severe symptoms develop. (
  • People living with Parkinson's disease (PD) can benefit from being physically active, especially when it comes to improving gait and balance, and reducing risks of falls. (
  • The Rev. Jesse Jackson Sr. revealed in a statement Friday that he has been diagnosed with Parkinson's disease. (
  • The 76-year-old civil rights leader said he had found it difficult to perform routine tasks and after a battery of tests was diagnosed by his physicians with Parkinson's, a disease that ailed his father. (
  • From a reported link to COVID-19 to new options for diagnosis and treatment, several significant recent news items made Parkinson's disease this week's top trending clinical topic. (
  • In all cases, brain imaging showed reduced function of the nigrostriatal dopamine system, as is seen in Parkinson's disease. (
  • The authors of the article believe that COVID-19 may predispose patients to develop Parkinson's disease either sooner or later. (
  • In terms of preventing Parkinson's disease, a new study suggests that coffee consumption is associated with a reduced risk in a particular subset of individuals. (
  • The study showed that caffeine levels were lower in patients with Parkinson's disease compared with controls, but this difference was much greater in individuals with a mutation in the leucine-rich repeat kinase 2 ( LRRK2 ) gene. (
  • A separate study recently investigated how gene variants may affect Parkinson's disease risk after pesticide exposure. (
  • Findings suggest that the likelihood of developing the condition is associated with prior exposure to occupational pesticides, both with regard to sporadic cases and among patients who have a GBA genetic risk variant for Parkinson's disease. (
  • In more encouraging news, Parkinson's disease may soon be diagnosed using a skin test . (
  • The skin testing showed a high degree of sensitivity and specificity for the diagnosis of Parkinson's disease. (
  • A study found that apomorphine sublingual film was efficacious and generally safe and well tolerated for the on-demand treatment of off episodes in Parkinson's disease. (
  • From COVID-related concerns to new developments in prevention, diagnosis, and treatment, various findings contributed to Parkinson's disease becoming this week's top trending clinical topic. (
  • Trending Clinical Topic: Parkinson's Disease - Medscape - Nov 20, 2020. (
  • Features differentiating the 2 forms of inflammatory bowel disease (IBD) are summarized in Table 1, below. (
  • Academic achievement, attendance, and school-related quality of life in pediatric inflammatory bowel disease. (
  • Nikolaus S, Schreiber S. Diagnostics of inflammatory bowel disease. (
  • More recently, progressive degenerative brain disease (chronic traumatic encephalopathy [CTE]) has been recognized in athletes with a history of multiple concussions, as well as milder blows to the head that do not cause concussion. (
  • Pediatric pancreas disease can include acute (sudden) and chronic (ongoing) episodes of pancreatitis (inflammation of the pancreas). (
  • The Liver Center at UC San Diego Health is the region's leader in the treatment of acute and chronic liver diseases. (
  • Chronic kidney disease (CKD) is irreversible and progressive, leading the person to renal replacement therapy. (
  • A talk with Nobel laureate Thomas C. Südhof about a scandal rocking the world of Alzheimer's research and how conceptions of the disease are changing. (
  • Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging. (
  • Madhusoodanan S, Shah P, Brenner R, Gupta S. Pharmacological treatment of the psychosis of Alzheimer's disease: what is the best approach? (
  • Learn how Alzheimer's disease affects a person's memory and other brain functions in our interactive online tour. (
  • The Alzheimer's Association is the leading voice for Alzheimer's disease advocacy, fighting for critical Alzheimer's research and care initiatives at the state and federal level. (
  • A laboratory study has found that the asthma drug salbutamol prevents the formation of tangles of fibrous protein that are a hallmark of Alzheimer's disease. (
  • They note that the most common form of dementia is Alzheimer's disease, which accounts for 60-70% of all cases. (
  • In the United States, the National Institute on Aging estimate that more than 5.5 million people have Alzheimer's disease. (
  • Researchers at Lancaster University in the United Kingdom believe that tau could be a more promising drug target for Alzheimer's disease. (
  • In Alzheimer's disease, these tau molecules break away from the microtubules and begin to stick together to form threads and, eventually, tangles. (
  • The scientists from Lancaster University believe that compounds that prevent tau molecules from aggregating in this way could make promising treatments for Alzheimer's disease. (
  • The scientists ruled out dobutamine as a practical treatment for Alzheimer's disease because it requires injection, and its effects are very short-lived. (
  • This work is in the very early stages, and we are some way from knowing whether or not salbutamol will be effective at treating Alzheimer's disease in human patients," says Prof. David Middleton, one of the authors. (
  • Salbutamol has already undergone extensive human safety reviews, and if follow-up research reveals an ability to impede Alzheimer's disease progression in cellular and animal models, this drug could offer a step forward, whilst drastically reducing the cost and time associated with typical drug development. (
  • Because of very rapid disease progression, close periodic monitoring by the multidisciplinary team is needed, typically every 14 days to evaluate needs for symptomatic treatment. (
  • In response to an outstanding request from 2017 for the establishment of a day dedicated to Chagas disease, the Board recommended that the Seventy-second World Health Assembly consider a draft decision on the establishment of World Chagas Disease Day. (
  • The Seventy-second World Health Assembly, having considered document A72/55 Rev.1, decided to establish World Chagas Disease Day. (
  • Triatomine bugs are a type of reduviid bug that can carry Trypanosoma cruzi , the parasite that causes Chagas disease. (
  • In areas of Latin America where human Chagas disease is an important public health problem, the bugs nest in cracks and holes of substandard housing. (
  • Can I get Trypanosoma cruzi , the parasite that causes Chagas disease, from a triatomine bug? (
  • Although it is unusual for patients with Parkinson disease to suffer from dementia (loss of thinking and problem-solving abilities in the early stages of the disorder, some do develop dementia-including hallucinations-in its later stages. (
  • There are many different diseases that can cause respiratory infections, so the scientists had to narrow down the possibilities. (
  • It's very rare, so isn't as widely known as other infections that deer ticks can spread, like Lyme disease . (
  • Screen sexually active teenagers for sexually transmitted diseases ( STDs ) and HIV . (
  • Examples include fatty liver disease and cirrhosis . (
  • Conditions such as viral hepatitis B or C, fatty liver disease, autoimmune liver disease and hemochromatosis can increase the risk of developing cirrhosis and liver cancer. (
  • Rohit Loomba Laboratory - fatty liver disease and nonalcoholic steatohepatitis. (
  • In some tropical and subtropical countries, for example, poliomyelitis is a rare clinical disease, though a common infection, but unimmunized visitors to such countries often contract serious clinical forms of the disease. (
  • However, our results justify further testing of salbutamol and similar drugs in animal models of the disease and, eventually, if successful, in clinical trials. (
  • ABSTRACT We studied 48 patients with Behçet disease to determine the clinical spectrum of the disease. (
  • Recently, the association between Behçet nization after history taking and clinical ex- disease and hepatitis C virus (HCV) [ 4-6 ] amination. (
  • Farmer RG, Hawk WA, Turnbull RB Jr. Clinical patterns in Crohn's disease: a statistical study of 615 cases. (
  • an infectious disease caused by the protozoan Trypanosoma cruzi, occurring chiefly in tropical America and characterized by irregular fever, palpable lymph nodes, and often heart damage. (
  • Depression is an important consideration in the differential diagnosis of Alzheimer disease (AD). (
  • The diagnosis of genetic prion disease is established in a proband with suggestive findings and a heterozygous PRNP pathogenic variant identified by molecular genetic testing. (
  • Definitive diagnosis is difficult, even in living animals, but the way the dinosaur's bones responded to the disease tracks how living vertebrates react to the same ailment. (
  • Role of genetics in the diagnosis and prognosis of Crohn's disease. (
  • Disease data source: World Health Organization. (
  • That such different-seeming diseases as psoriasis and diabetes could stem from a common cause actually is a relatively new notion, according to Noel R. Rose, MD, PhD, professor of molecular microbiology and immunology and pathology at the Johns Hopkins University in Baltimore. (
  • Huntington's disease affects an estimated 3 to 7 per 100,000 people of European ancestry. (
  • Parkinson disease is a disorder that affects the patient's ability to move smoothly and at a normal rate. (
  • Ebola diseases (EBOD) are rare, but severe and often fatal viral diseases that affects humans and other primates. (
  • Both asymptomatic carriers and people with overt meningococcal disease can be sources of infection. (
  • Recurrent Lyme Disease: Old or New Infection? (
  • Tests such as imaging tests and liver function tests can check for liver damage and help to diagnose liver diseases. (
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (
  • Diseases caused by drugs, poisons, or too much alcohol. (
  • During the 2018-2020 Ebola virus disease (EVD) outbreak caused by Zaire ebolavirus in the Democratic Republic of the Congo, the first-ever multi-drug randomized control trial was conducted to evaluate the effectiveness and safety of drugs used in the treatment of EVD patients under an ethical framework developed in consultation with experts in the field and the DRC. (
  • Cardiovascular disease (CVD) is the number one cause of death in the modern world, with more people dying annually from CVDs than from any other cause. (
  • The idea originated following a poster symposium at the Annual 2015 Meeting of the American Association of Physical Anthropologists in St Louis, Missouri (The Bioarchaeology of Cardiovascular Disease), organized by Michaela Binder & Charlotte Roberts. (
  • Climbing more than five flights of stairs daily is associated with a reduced risk of atherosclerotic cardiovascular disease (ASCVD) of about 20%, new observational data suggest. (
  • There is, therefore, no case for recommending viral screening for HBV and HCV in Behçet disease patients at present. (
  • and major agents of viral hepatitis, we car- ried out a case-control study in Kerman, a Behçet disease, a multisystem vasculitis, is southern province in the Islamic Republic seen most frequently in Far Eastern and of Iran. (
  • Cases of ASCVD - defined as coronary artery disease (CAD), ischemic stroke , or acute complications - were identified via hospital records and death registry. (
  • NORD is not a medical provider or health care facility and thus can neither diagnose any disease or disorder nor endorse or recommend any specific medical treatments. (
  • Meningococcal disease progresses rapidly and has a case-fatality rate of 10%-15%, even with antimicrobial drug treatment. (
  • As the disease progresses, these movements become more pronounced. (
  • In other words, if your parents have a predisposition to autoimmune disease, you may, too. (
  • If you have one autoimmune disease, you may have more -- and you may have different ones than your parent did (or your siblings do). (
  • Another common characteristic of all autoimmune diseases is that it is thought that an outside agent is required to start the process. (
  • Even with a genetic tendency, a person may not develop an autoimmune disease without an environmental influence to set it off. (
  • Genetic prion disease is inherited in an autosomal dominant manner. (
  • Adult-onset Huntington's disease, the most common form of this disorder, usually appears in a person's thirties or forties. (
  • In rare cases, an individual with Huntington's disease does not have a parent with the disorder. (
  • People with the adult-onset form of Huntington's disease typically have 40 to 50 CAG repeats in the HTT gene, while people with the juvenile form of the disorder tend to have more than 60 CAG repeats. (
  • Individuals who have 27 to 35 CAG repeats in the HTT gene do not develop Huntington's disease, but they are at risk of having children who will develop the disorder. (
  • Parkinson disease is almost entirely a disorder of older adults. (
  • Other individuals with genetic prion disease may have the disorder as the result of a de novo PRNP pathogenic variant. (
  • Feline hyperthyroidism, usually characterized by weight loss, hyperactivity, and eventual heart disease, is now the leading hormonal disorder in cats. (
  • The disease is a neurological disorder in which the death of brain cells results in progressive memory loss and cognitive decline. (
  • What are the causes of Pediatric Pancreas Disease? (
  • The three major phenotypes of genetic prion disease are genetic Creutzfeldt-Jakob disease (gCJD), fatal familial insomnia (FFI), and Gerstmann-Sträussler-Scheinker (GSS) syndrome. (
  • The disease might have then proven fatal for Dolly of its own accord, or it's possible that a hungry predator saw the ailing dinosaur as an easy lunch. (
  • By contrast, rates of disease in Australia, Europe, South America, and the United States range from 0.10-2.4 cases per 100,000 population per year. (
  • The Cribsiders talk about having a low threshold for testing a child for celiac disease, and which tests to order first. (
  • Humans have a high degree of resistance to foot-and-mouth disease , for example, while the cattle and sheep with which they may be in close contact suffer in the thousands from it. (
  • Although meningococcal disease outbreaks can occur anywhere in the world, they are most common in the African meningitis belt, where large-scale epidemics occur every 5-12 years. (
  • The Hajj pilgrimage to Saudi Arabia also has been associated with outbreaks of meningococcal disease among returning pilgrims and their contacts, including 4 cases in travelers from the United States during a large Hajj-associated outbreak in 2000. (
  • The first cases of Ebola diseases were detected in two concomitants outbreaks in Sudan and in Zaire (now the Democratic Republic of the Congo) in 1976. (
  • Variants (also called mutations) in the HTT gene cause Huntington's disease. (
  • As the gene is passed from parent to child, the size of the CAG trinucleotide repeat may lengthen into the range associated with Huntington's disease (36 repeats or more). (
  • Your child may be born with pancreas disease if they inherit a gene mutation (permanent change). (
  • Your child is at risk for pancreas disease if they inherit the gene mutation. (
  • A variety of intestinal manifestations and extraintestinal manifestations (EIMs) also may be observed in conjunction with either Crohn disease or ulcerative colitis. (
  • In this context, the communication between the health professional and the user is essential, since it can make possible a better understanding of the disease and the therapeutics and the greater appropriation of (self) health care. (
  • What's involved with teen disease prevention? (
  • Teen disease prevention includes maintaining a healthy diet , exercising regularly, preventing injuries, and screening annually for potential health conditions that could adversely affect teenage health. (
  • Also, the number of tangles in the brain appears to be a much better indicator of the severity of the disease than the number of amyloid plaques. (
  • These findings not only offer new information about disease in the past, but also allow for new insights into the evolution and aetiology of CVDs through contextualized bioarchaeological studies and biomolecular approaches. (
  • Meningococcal disease refers to any illness caused by bacteria called Neisseria meningitidis . (
  • Powassan virus disease is an illness caused by a virus that can spread to people through the bite of an infected tick. (
  • Receiving complement inhibitors such as eculizumab (Soliris®) or ravulizumab (Ultomiris™) increases your risk for meningococcal disease. (
  • Unvaccinated travelers visiting meningitis belt countries and having prolonged contact with local populations during an epidemic are at greatest risk for meningococcal disease. (
  • People who have a parent or sibling with Parkinson disease have a slightly increased risk (5 percent) of developing the disease themselves. (
  • Who is at risk for pancreas disease? (
  • Risk stratification of emergency department patients with Crohn's disease could reduce computed tomography use by nearly half. (
  • He invents all sorts of disease to torment himself. (
  • Specimens such as this can help shed light on what sorts of diseases were affecting dinosaurs millions of years ago," says University of Wisconsin Oshkosh paleontologist Joseph Peterson , who was not part of the study team. (
  • Meningococcal disease generally occurs 1-10 days after exposure and presents as meningitis in ≈50% of cases in the United States. (
  • A less common form of Huntington's disease known as the juvenile form begins in childhood or adolescence. (
  • Meningococcal disease is hyperendemic in this region, and periodic epidemics during the dry season (December-June) reach an incidence of up to 1,000 cases per 100,000 population. (
  • Worldwide, the frequency of Parkinson disease is thought to be about 120 persons in every 100,000. (