Chlorinated hydrocarbons containing heteroatoms that are present as contaminants of herbicides. Dioxins are carcinogenic, teratogenic, and mutagenic. They have been banned from use by the FDA.
Compounds that contain a BENZENE ring fused to a furan ring.
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
A chemical by-product that results from burning or incinerating chlorinated industrial chemicals and other hydrocarbons. This compound is considered an environmental toxin, and may pose reproductive, as well as, other health risks for animals and humans.
High temperature destruction of waste by burning with subsequent reduction to ashes or conversion to an inert mass.
Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.
The discarding or destroying of garbage, sewage, or other waste matter or its transformation into something useful or innocuous.
The total amount of a chemical, metal or radioactive substance present at any time after absorption in the body of man or animal.
Phenols substituted with one or more chlorine atoms in any position.
Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading.
Plugs or cylinders made of cotton, sponge, or other absorbent material. They are used in surgery to absorb fluids such as blood or drainage.
Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.
The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.
Hydrocarbon compounds with one or more of the hydrogens replaced by CHLORINE.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment.
Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.
Food products manufactured from poultry.
A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.
High-molecular-weight insoluble polymers that contain functional cationic groups capable of undergoing exchange reactions with anions.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Uncontrolled release of a chemical from its containment that either threatens to, or does, cause exposure to a chemical hazard. Such an incident may occur accidentally or deliberately.
Pesticides or their breakdown products remaining in the environment following their normal use or accidental contamination.
The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, or during a 24-hour period in the general population, which does not appear to cause appreciable harm, whether immediate or delayed for any period, in the target population. (From Lewis Dictionary of Toxicology, 1st ed)
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE.
A CHROMATOGRAPHY method using supercritical fluid, usually carbon dioxide under very high pressure (around 73 atmospheres or 1070 psi at room temperature) as the mobile phase. Other solvents are sometimes added as modifiers. This is used both for analytical (SFC) and extraction (SFE) purposes.
Phylum of green nonsulfur bacteria including the family Chloroflexaceae, among others.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A greenish-yellow, diatomic gas that is a member of the halogen family of elements. It has the atomic symbol Cl, atomic number 17, and atomic weight 70.906. It is a powerful irritant that can cause fatal pulmonary edema. Chlorine is used in manufacturing, as a reagent in synthetic chemistry, for water purification, and in the production of chlorinated lime, which is used in fabric bleaching.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.
The fifth planet in order from the sun. It is one of the five outer planets of the solar system. Its sixteen natural satellites include Callisto, Europa, Ganymede, and Io.
Garbage, refuse, or sludge, or other discarded materials from a wastewater treatment plant, water supply treatment plant, and air pollution control facility that include solid, semi-solid, or contained material. It does not include materials dissolved in domestic sewage, irrigation return flows, or industrial discharges.
Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)
Small solar system planetary bodies including asteroids. Most asteroids are found within the gap lying between the orbits of Mars and Jupiter.
The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.
Printed publications usually having a format with no binding and no cover and having fewer than some set number of pages. They are often devoted to a single subject.
An agency in the Executive Branch of the Federal Government. It was created as an independent regulatory agency responsible for the implementation of federal laws designed to protect the environment. Its mission is to protect human health and the ENVIRONMENT.
Substances or organisms which pollute the water or bodies of water. Use for water pollutants in general or those for which there is no specific heading.

Relationships between environmental organochlorine contaminant residues, plasma corticosterone concentrations, and intermediary metabolic enzyme activities in Great Lakes herring gull embryos. (1/575)

Experiments were conducted to survey and detect differences in plasma corticosterone concentrations and intermediary metabolic enzyme activities in herring gull (Larus argentatus) embryos environmentally exposed to organochlorine contaminants in ovo. Unincubated fertile herring gull eggs were collected from an Atlantic coast control site and various Great Lakes sites in 1997 and artificially incubated in the laboratory. Liver and/or kidney tissues from approximately half of the late-stage embryos were analyzed for the activities of various intermediary metabolic enzymes known to be regulated, at least in part, by corticosteroids. Basal plasma corticosterone concentrations were determined for the remaining embryos. Yolk sacs were collected from each embryo and a subset was analyzed for organochlorine contaminants. Regression analysis of individual yolk sac organochlorine residue concentrations, or 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQs), with individual basal plasma corticosterone concentrations indicated statistically significant inverse relationships for polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans (PCDDs/PCDFs), total polychlorinated biphenyls (PCBs), non-ortho PCBs, and TEQs. Similarly, inverse relationships were observed for the activities of two intermediary metabolic enzymes (phosphoenolpyruvate carboxykinase and malic enzyme) when regressed against PCDDs/PCDFs. Overall, these data suggest that current levels of organochlorine contamination may be affecting the hypothalamo-pituitary-adrenal axis and associated intermediary metabolic pathways in environmentally exposed herring gull embryos in the Great Lakes.  (+info)

Effects of dioxins on human health: a review. (2/575)

The toxicity of 2,3,7,8-tetrachlorodibenzodioxin (TCDD) has been known since 1950s. TCDD is a by-product of herbicide 2,4-dichloroacetophenol (2,4-D) and 2,4,5-trichloroacetophenol (2,4,5-T), but it was first found in fryash of municipal incinerator in 1979 in Japan. In 1998, the survey of municipal incinerators revealed that 105 out of 1,641 produced above the allowed emission level of 80 ng TEQ/m3. Total annual release of dioxins is estimated to be about 5,000 g TEQ in 1997 in Japan. Japanese government started a comprehensive survey for dioxin levels in milk and blood of residents around incinerators, and their health effects. Human effects by dioxin exposures in Western countries were mostly acute and at high level in accidentally and/or occupationally. Health effects of low-dose and long lasting exposure has not been well understood. Certain amount of polychlorinated dibenzo-p-dioxins (PCDD), dibenzofurans (PCDF) and polychlorinated biphenyls (PCB) is accumulated in our body. Mother's milk is also contaminated by PCDD/PCDF. Health effects of the polychlorinated chemicals are summarized, and the necessity of regulations and recommendations for making a guideline is discussed in this review.  (+info)

Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation. (3/575)

The aryl hydrocarbon receptor (AHR) and the alpha-class hypoxia inducible factors (HIF1alpha, HIF2alpha, and HIF3alpha) are basic helix-loop-helix PAS (bHLH-PAS) proteins that heterodimerize with ARNT. In response to 2,3,7,8-tetrachlorodibenzo-p-dioxin, the AHR. ARNT complex binds to "dioxin responsive enhancers" (DREs) and activates genes involved in the metabolism of xenobiotics, e.g. cytochrome P4501A1 (Cyp1a1). The HIF1alpha.ARNT complex binds to "hypoxia responsive enhancers" and activates the transcription of genes that regulate adaptation to low oxygen, e.g. erythropoietin (Epo). We postulated that activation of one pathway would inhibit the other due to competition for ARNT or other limiting cellular factors. Using pathway specific reporters in transient transfection assays, we observed that DRE driven transcription was markedly inhibited by hypoxia and that hypoxia responsive enhancer driven transcription was inhibited by AHR agonists. When we attempted to support this cross-talk model using endogenous loci, we observed that activation of the hypoxia pathway inhibited Cyp1a1 up-regulation, but that activation of the AHR actually enhanced the induction of Epo by hypoxia. To explain this unexpected additivity, we examined the Epo gene and found that its promoter harbors DREs immediately upstream of its transcriptional start site. These experiments outline conditions where inhibitory and additive cross-talk occur between the hypoxia and dioxin signal transduction pathways and identify Epo as an AHR-regulated gene.  (+info)

Removal of dibenzofuran, dibenzo-p-dioxin, and 2-chlorodibenzo-p-dioxin from soils inoculated with Sphingomonas sp. strain RW1. (4/575)

Removal of dibenzofuran, dibenzo-p-dioxin, and 2-chlorodibenzo-p-dioxin (2-CDD) (10 ppm each) from soil microcosms to final concentrations in the parts-per-billion range was affected by the addition of Sphingomonas sp. strain RW1. Rates and extents of removal were influenced by the density of RW1 organisms. For 2-CDD, the rate of removal was dependent on the content of soil organic matter (SOM), with half-life values ranging from 5.8 h (0% SOM) to 26.3 h (5.5% SOM).  (+info)

Repression of dioxin signal transduction in fibroblasts. Identification Of a putative repressor associated with Arnt. (5/575)

Heterodimeric complexes of basic helix-loop-helix/PAS transcription factors are involved in regulation of diverse physiological phenomena such as circadian rhythms, reaction to low oxygen tension, and detoxification. In fibroblasts, the basic helix-loop-helix/PAS heterodimer consisting of the ligand-inducible dioxin receptor and Arnt shows DNA-binding activity, and the receptor and Arnt are able to activate transcription when fused to a heterologous DNA-binding domain. However, fibroblasts are nonresponsive to dioxin with regard to induction mediated by the DNA response element recognized by the receptor and Arnt. Here we demonstrate that Arnt is associated with a fibroblast-specific factor, forming a complex that is capable of binding the dioxin response element. This factor may function as a repressor since negative regulation of target gene induction appears to be abolished by inhibition of histone deacetylase activity by trichostatin A. Finally, the negative regulatory function of this factor appears to be restricted for dioxin signaling since Arnt was able to mediate, together with hypoxia-inducible factor-1alpha, transcriptional activation in hypoxic cells. Taken together, these data suggest that fibroblast-specific inhibition of dioxin responsiveness involves recruitment by Arnt of a cell type- and signaling pathway-specific corepressor associated with a histone deacetylase.  (+info)

Aromatic hydrocarbon nuclear translocator as a common component for the hypoxia- and dioxin-induced gene expression. (6/575)

Aromatic hydrocarbon nuclear translocator (Arnt) is an ubiquitously expressed protein that contains basic helix-loop-helix (bHLH) and Per-AhR-Arnt-Sim (PAS) motifs. Other bHLH-PAS proteins, hypoxia-inducible factor-1alpha (HIF-1alpha) and aromatic hydrocarbon receptor (AhR) mediate hypoxia- and dioxin-signal pathway, respectively. Arnt has been identified as a heterodimerization partner for AhR. AhR/Arnt heterodimer binds the regulatory region of xenobiotic-induced genes and activates their transcription. Here, in vivo results provide evidence that Arnt is involved in not only xenobiotic- but also hypoxia-induced transcriptional activation. In hypoxic condition, Arnt dimerizes with HIF-1alpha to make HIF-1alpha/Arnt heterodimer which is able to bind hypoxia-responsive DNA elements. The HIF-1alpha/Arnt heterodimer functions as a transactivator for hypoxia-inducible genes. Given that the expression of Arnt is limited, HIF-1alpha may compete with AhR for recruiting Arnt as a heteromeric partner. Consistent with this idea, the results indicate that the hypoxic activation of HIF-1alpha reduces dioxin-induced AhR's function on the dioxin-responsive reporter gene and the endogenous gene.  (+info)

A functional 4-hydroxysalicylate/hydroxyquinol degradative pathway gene cluster is linked to the initial dibenzo-p-dioxin pathway genes in Sphingomonas sp. strain RW1. (7/575)

The bacterium Sphingomonas sp. strain RW1 is able to use dibenzo-p-dioxin, dibenzofuran, and several hydroxylated derivatives as sole sources of carbon and energy. We have determined and analyzed the nucleic acid sequence of a 9,997-bp HindIII fragment downstream of cistrons dxnA1A2, which encode the dioxygenase component of the initial dioxygenase system of the corresponding catabolic pathways. This fragment contains 10 colinear open reading frames (ORFs), apparently organized in one compact operon. The enzymatic activities of some proteins encoded by these genes were analyzed in the strain RW1 and, after hyperexpression, in Escherichia coli. The first three ORFs of the locus, designated dxnC, ORF2, and fdx3, specify a protein with a low homology to bacterial siderophore receptors, a polypeptide representing no significant homology to known proteins, and a putative ferredoxin, respectively. dxnD encodes a 69-kDa phenol monooxygenase-like protein with activity for the turnover of 4-hydroxysalicylate, and dxnE codes for a 37-kDa protein whose sequence and activity are similar to those of known maleylacetate reductases. The following gene, dxnF, encodes a 33-kDa intradiol dioxygenase which efficiently cleaves hydroxyquinol, yielding maleylacetate, the ketoform of 3-hydroxy-cis,cis-muconate. The heteromeric protein encoded by dxnGH is a 3-oxoadipate succinyl coenzyme A (succinyl-CoA) transferase, whereas dxnI specifies a protein exhibiting marked homology to acetyl-CoA acetyltransferases (thiolases). The last ORF of the sequenced fragment codes for a putative transposase. DxnD, DxnF, DxnE, DxnGH, and DxnI (the activities of most of them have also been detected in strain RW1) thus form a complete 4-hydroxysalicylate/hydroxyquinol degradative pathway. A route for the mineralization of the growth substrates 3-hydroxydibenzofuran and 2-hydroxydibenzo-p-dioxin in Sphingomonas sp. strain RW1 thus suggests itself.  (+info)

Chlorella accelerates dioxin excretion in rats. (8/575)

We investigated the effects of Chlorella on fecal excretion of polychlorinated dibenzo-p-dioxin (PCDD) congeners and polychlorinated dibenzofuran (PCDF) congeners in Wistar rats administered the rice oil that caused Yusho disease, as a substitute for purified dioxin. The rats were fed 4 g of a control diet or a 10% Chlorella diet containing 0.2 mL of the rice oil once during the 5-d experimental period. The amounts of PCDD and PCDF congeners excreted in feces from d 1 to 5 in the group fed 10% Chlorella were 0.2-11.3 and 0.3-12.8 times greater (P < 0.05), respectively, than those of the control group. We then investigated the fecal excretion of PCDD and PCDF congeners from d 8 to 35 in rats administered 0.5 mL of the rice oil. Rats consumed the basal diet for 1 wk. After 1 wk, they consumed either the basal diet or the 10% Chorella diet. The fecal excretions of PCDD and PCDF congeners in the group fed 10% Chlorella were 0.3-3.4 and 0.5-2.5 times greater (most, P < 0.05), respectively, than those of the control group. Thus, the fecal excretions of PCDD and PCDF congeners were greater in rats fed Chlorella. These findings suggest that the administration of Chlorella may be useful in preventing gastrointestinal absorption and for promoting the excretion of dioxin already absorbed into tissues. Moreover, these findings suggest that Chlorella might be useful in the treatment of humans exposed to dioxin.  (+info)

Dioxins and dioxin-like compounds (DLCs) are compounds that are highly toxic environmental persistent organic pollutants (POPs). They are mostly by-products of various industrial processes - or, in case of dioxin-like PCBs and PBBs, part of intentionally produced mixtures. They include: Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo-p-dioxin. There are 75 PCDD congeners, differing in the number and location of chlorine atoms, and seven of them are especially toxic, the most dangerous being 2,3,7,8-Tetrachlorodibenzodioxin (TCDD) Polychlorinated dibenzofurans (PCDFs), or furans. PCDFs are derivatives of dibenzofuran. There are 135 isomers, ten have dioxin-like properties. Polychlorinated/polybrominated biphenyls (PCBs/PBBs), derived from biphenyl, of which twelve are dioxin-like. Under certain conditions PCBs may form dibenzofurans/dioxins through partial oxidation. Finally, dioxin may refer to 1,4-Dioxin proper, the basic chemical unit of the ...
Dioxins and dioxin-like polychlorinated biphenyls (DL-PCBs) are hazardous toxic, ubiquitous and persistent chemical compounds, which can enter the food chain and accumulate up to higher trophic levels. Their determination requires sophisticated methods, expensive facilities and instruments, well-trained personnel and expensive chemical reagents. Ideally, real-time monitoring using rapid detection methods should be applied to detect possible contamination along the food chain in order to prevent human exposure. Sensor technology may be promising in this respect. This review gives the state of the art for detecting possible contamination with dioxins and DL-PCBs along the food chain of animal-source foods. The main detection methods applied (i.e., high resolution gas-chromatography combined with high resolution mass-spectrometry (HRGC/HRMS) and the chemical activated luciferase gene expression method (CALUX bioassay)), each have their limitations. Biosensors for detecting dioxins and related compounds,
Dioxins and dioxin-like polychlorinated biphenyls (DL-PCBs) are hazardous toxic, ubiquitous and persistent chemical compounds, which can enter the food chain and accumulate up to higher trophic levels. Their determination requires sophisticated methods, expensive facilities and instruments, well-trained personnel and expensive chemical reagents. Ideally, real-time monitoring using rapid detection methods should be applied to detect possible contamination along the food chain in order to prevent human exposure. Sensor technology may be promising in this respect. This review gives the state of the art for detecting possible contamination with dioxins and DL-PCBs along the food chain of animal-source foods. The main detection methods applied (i.e., high resolution gas-chromatography combined with high resolution mass-spectrometry (HRGC/HRMS) and the chemical activated luciferase gene expression method (CALUX bioassay)), each have their limitations. Biosensors for detecting dioxins and related compounds,
Dioxins refers to a group of persistent chlorinated chemical compounds that have similar chemical structures and properties, and have similar biological characteristics, including toxicity. Food Standards Australia New Zealand (FSANZ) has conducted an analytical survey of dioxins in a range of food sampled in Australia with the purpose of assessing the level of risk to human health associated with the dietary exposure of the Australian population to dioxins. The overall conclusion of this report is that, on the basis of the available data, taking into account all the inherent uncertainties and limitations, the public health and safety risk for all Australians from exposure to dioxins from foods is very low.. Dioxins includes the polychlorinated dibenzodioxins (PCDDs or dioxins), the closely related polychlorinated dibenzofurans (PCDFs or furans) and polychlorinated biphenyls (dioxin-like PCBs, or PCBs). These compounds can accumulate in the body fat of animals and humans and have a tendency ...
TY - JOUR. T1 - Concentrations of dioxins and other organochlorines (PCBs, DDTs, HCHs) in human milk from Seveso, Milan and a Lombardian rural area in Italy. T2 - A study performed 25 years after the heavy dioxin exposure in Seveso. AU - Weiss, J.. AU - Päpke, O.. AU - Bignert, A.. AU - Jensen, S.. AU - Greyerz, E.. AU - Agostoni, C.. AU - Besana, R.. AU - Riva, E.. AU - Giovannini, M.. AU - Zetterström, Rolf. PY - 2003/4/1. Y1 - 2003/4/1. N2 - Aim: To investigate whether those who were exposed to high levels of the dioxin TCDD 25 years ago in Seveso, northern Italy still have higher than the expected levels of dioxins in their fat stores, and to investigate the concentrations of dioxins in the breast milk of mothers in Seveso and in two other regions in Italy. The load of vertically transmitted dioxins to the next generation, if being breastfed, was also investigated. Methods: As there may be a synergistic effect of mixtures of organic chlorines, the concentrations of pesticides such as DDTs ...
Dioxins and polychlorinated biphenyls (PCBs) are toxic chemicals that persist in the environment and accumulate in the food chain. Their presence in the environment in Europe has declined since the 1970s, following concerted efforts by public authorities and industry.. In the context of EFSAs work, dioxins refers to two groups of compounds: Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Dioxins have no technological or other use, but are generated in a number of thermal and industrial processes as unwanted and often unavoidable by-products. In contrast to dioxins, PCBs had widespread use in numerous industrial applications, and were produced in large quantities for several decades with an estimated total world production of 1.2-1.5 million tonnes, until they were banned in most countries by the 1980s.. Dioxins and PCBs are found at low levels in many foods. Longer-term exposure to these substances has been shown to cause a range of adverse effects on the nervous, immune ...
Dioxins and polychlorinated biphenyls (PCBs) are toxic chemicals that persist in the environment and accumulate in the food chain. Their presence in the environment in Europe has declined since the 1970s, following concerted efforts by public authorities and industry.. In the context of EFSAs work, dioxins refers to two groups of compounds: Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Dioxins have no technological or other use, but are generated in a number of thermal and industrial processes as unwanted and often unavoidable by-products. In contrast to dioxins, PCBs had widespread use in numerous industrial applications, and were produced in large quantities for several decades with an estimated total world production of 1.2-1.5 million tonnes, until they were banned in most countries by the 1980s.. Dioxins and PCBs are found at low levels in many foods. Longer-term exposure to these substances has been shown to cause a range of adverse effects on the nervous, immune ...
Dioxins are extremely widespread, toxic and persistent pollutants, as well as a major concern for human health. The Aryl hydrocarbon receptor (Ahr) is the key component in the metabolic response to dioxins. Ahr is a cytoplasmic bHLH-PAS transcription factor that, upon binding with dioxin, translocates to the nucleus. There it forms a complex with the Ah receptor nuclear transloator (Arnt), another bHLH-PAS protein, and binds to the eight-nucleotide XRE motif to control gene expression. Previous work with Ahr knock-out mice revealed the existence of dioxin-independent activity for Ahr in development, but the relationship between the two activities of Ahr remains unclear. Our work uses Drosophila to clarify this question, which is central for therapies seeking inactivation of Ahr. The Drosophila Ahr homologue, spineless(ss), does not bind dioxins, however, it physically interacts with Tango (Tgo), Arnts fly homologue, and controls gene expression through the XRE motif during development. Here I ...
Industrial activities: Dioxin is not produced or used commercially in the United States. It is a contaminant formed during the production of some chlorinated organic compounds, including a few herbicides such as Silvex. Over the past decade, EPA and industry have been working together to dramatically reduce the production of dioxin and its release to the environment.. Although environmental levels of dioxins have decreased in the last 30 years, dioxins are extremely persistent compounds and break down very slowly. In fact, a large part of current exposures to dioxins in the United States is due to releases that occurred decades ago (e.g., pollution, fires).. Even if all human-generated dioxins were eliminated, low levels of naturally produced dioxins would remain. EPA and its government partners are looking for ways to further reduce dioxins entering the environment and to reduce human exposure to them.. Other ways dioxins are produced:. Burning: Combustion processes such as waste incineration ...
Maximum levels set by the European Commission for thesum of dioxins (WHO-PCDD/F-TEQ) for marine oils (fish body oil, fish liver oil and oils of other marine organisms intended for human consumption): 1.75 ng/kg fat. #Maximum levels set by the European Commission for thesum of dioxins and dioxin like PCBs (WHO-PCDD/F-PCB-TEQ) for marine oils (fish body oil, fish liver oil and oils of other marine organisms intended for human consumption): 6.0 ng/kg fat. # Dioxins (sum of polychlorinated dibenzo-para-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), expressed as World Health Organisation (WHO) toxic equivalent using the WHO-toxic equivalency factors (WHO-TEFs)) and sum of dioxins and dioxin-like PCBs (sum of PCDDs, PCDFs and polychlorinated biphenyls (PCBs), expressed as WHO toxic equivalent using the WHO-TEFs). WHO-TEFs for human risk assessment based on the conclusions of the World Health Organization (WHO) - International Programme on Chemical Safety (IPCS) expert meeting which was ...
All groups of dioxin-like compounds are persistent in the environment.[61] Very few soil microbes nor animals are able to break down effectively the PCDD/Fs with lateral chlorines (positions 2,3,7, and 8). This causes very slow elimination. However scientists at Martin Luther University recently found that a type of bacteria Dehalococcoides CBDB1 can extract the chlorine from dioxin compounds in the absence of oxygen.[62][63] Ultraviolet light is able to slowly break down these compounds. Lipophilicity (tendency to seek for fat-like environments) and very poor water solubility make these compounds move from water environment to living organisms having lipid cell structures. This is called bioaccumulation. Increase in chlorination increases both stability and lipophilicity. The compounds with the very highest chlorine numbers (e.g. octachlorodibenzo-p-dioxin) are, however, so poorly soluble that this hinders their bioaccumulation.[61] Bioaccumulation is followed by biomagnification. Lipid-soluble ...
An urgent review is underway after an ABC Four Corners investigation found elevated levels of dangerous dibenzo-para-dioxins - dioxins - in a generic version of 24D, one of Australias most widely used herbicides. 2,4-D is used in many commercial products including; Bayer All-In-One, Nufarm, Kuziherb, Hi-Yield, Weedtrine, Aqua-Kleen, Barrage, Plantgard, Lawn-Keep, Planotox, Malerbane, Speedzone and Dupont 24D. While this latest scare focuses on commercially used chemicals, it is likely that domestic-use herbicides and pesticides contain the same dioxins.. Dioxins are one of the most toxic chemical compounds in the world - Australian authorities dont routinely test for them - dioxins break down extremely slowly in the environment, they bioaccumulate - collect in fatty tissue - becoming concentrated in animals higher up the food chain. Dioxins are almost exclusively man-made. In herbicides 2,4-D is used widely to control many types of broadleaf weed, and belongs to the Dirty Dozen Persistent ...
INDIUM: One of the common reasons for halogen elimination in electronics is based around the possibility that halogens can form dioxins when that halogenated product is burned. Dioxins are...
Survey Methodology. The principal mechanism for the entry of dioxins into the environment in Ireland is by low-level emissions from multiple combustion sources to the atmosphere, with subsequent deposition onto vegetation such as grass. Any dioxins on grass ingested by cows tend to concentrate in the milk fat. Hence, sampling for dioxin levels in the milk of grazing cows is the approach adopted. The survey was carried out between June and early August 2011, during the peak outdoor grazing season, by taking a series of milk samples mainly from representative regional dairies. Additional samples were also taken from localities that might be seen as areas of potential risk of raised dioxin levels.. The WHO Toxic Equivalent is the current internationally recognised system for comparing dioxin toxicities of different samples. Samples were tested for dioxins only and for dioxins and PCBs combined and the levels found were well below the EU limit in milk and milk products. In view of the increased ...
TY - JOUR. T1 - Dioxin exposure and age of pubertal onset among Russian boys. AU - Korrick, Susan A.. AU - Lee, Mary M.. AU - Williams, Paige L.. AU - Sergeyev, Oleg. AU - Burns, Jane S.. AU - Patterson, Donald G.. AU - Turner, Wayman E.. AU - Needham, Larry L.. AU - Altshul, Larisa. AU - Revich, Boris. AU - Hauser, Russ. PY - 2011/9/1. Y1 - 2011/9/1. N2 - Background: Animal data demonstrate associations of dioxin, furan, and polychlorinated biphenyl (PCB) exposures with altered male gonadal maturation. It is unclear whether these associations apply to human populations. bjectives: We investigated the association of dioxins, furans, PCBs, and corresponding toxic equivalent (TEQ) concentrations with pubertal onset among boys in a dioxin-contaminated region. ethods: Between 2003 and 2005, 499 boys 8-9 years of age were enrolled in a longitudinal study in Chapaevsk, Russia. Pubertal onset [stage 2 or higher for genitalia (G2+) or testicular volume (TV) , 3 mL] was assessed annually between ages 8 ...
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: Battelle Columbus TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) DATE: 07/14/03 EXPERIMENT: 96007 TEST: 05 TIME: 14:21:29 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: GAVAGE NTP: C96007F ------------------------------------------------------------------------------------------------------------------------------------ REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: BATTELLE COLUMBUS TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) DATE: 07/14/03 EXPERIMENT: 96007 TEST: 05 TIME: 14:35:48 SPECIES: RATS, SPRAGUE-DAWLEY TEST TYPE: TWO YEAR ROUTE: ORAL GAVAGE NTP: 96007F CONT: NO1-ES-75411 CAS: 57117-31-4 MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE TWO YEAR ORAL GAVAGE STUDY OF TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) ...
The Minnesota Department of Health (MDH) has prepared this memo in response to your January 28, 2003, request for guidance on dioxin, as well as to identify a consistent approach for agencies and programs to assess the carcinogenic health risks from exposure to dioxin-like compounds. Guidance for assessing the noncancer health risks is still under development and will not be addressed in this memo. Because of the uncertainties associated with the toxicities of dioxin mixtures, MDH uses a conservative approach to evaluate potential risks. As more data become available, MDH re-evaluates and revises its risk assessment methods and procedures, as appropriate. Dioxin-like Compounds. The term dioxins is used to refer to a family of complex but related chlorinated compounds with similar chemical structures and biological activity. The polychlorinated dibenzo-p-dioxins (PCDDs) include 75 individual compounds, the polychlorinated dibenzofurans (PCDFs) include 135 individual compounds, and the ...
compliance testing with regard to the action levels and maximum levels for dioxins, dioxin-like PCBs and non-dioxin-like PCBs Recommendation 2014/633/EU. Feed:
Three Case Studies from Mad Cows and Mothers Milk: Dioxins, or Chemical Stigmata; Hamburger Hell; & Mothers Milk By: Cameron A. Straughan June 29, 2002 I chose to read Mad Cows and Mothers Milk mainly because it deals in depth with risk communication concerning PCBs and Dioxins - something I have had ample experience with.…
Dioxins are a group of persistent environmental pollutants (POPs) that comprise of chlorinated organic chemicals. These airborne particles can deposit on plants or in water, and animals can accumulate these highly toxic molecules in their fat.
To gather the droplets, Dr Hanano and his colleagues first softened up their date stones by soaking them in water for two weeks. That done, they ground them up and centrifuged the result. This process separated the droplets from the rest of the gunk as a creamy emulsion. It was then a question of testing the emulsions ability to extract dioxins from water. As the group report in Frontiers in Plant Science, it did this well. The droplets phospholipid membranes proved no barrier to the passage of dioxins, which accumulated satisfactorily in the oil. One of Dr Hananos collaborators, Denis Murphy of the University of South Wales, in Britain, describes the droplets as acting like little magnets for dioxins. Within a minute, he says, virtually all the dioxins are sucked out of a solution. It is very fast. ...
As the measurements of PCDD/PCDFs are complex, there is no reliable estimation of emissions in most of low- and middle-income countries. In order to help countries identify sources of emissions and to estimate release of PCDD/PCDFs, the United Nations Environment Program (UNEP) has established a Toolkit for Identification and Quantification of Releases of Dioxins, Furans and Other Unintentional Persistent Organic Pollutants (POPs) [21, 22]. The main objective of the Toolkit is to estimate the PCDD/PCDFs emissions from existing sources to the air, water, land, residue, and other products [22]. Therefore, emissions of PCDD/PCDFs were estimated by the methods proposed by the UNEP Toolkit, which consists of five-steps [21-23]. They are 1) the use of screening matrix to identify the major source categories of PCDD/PCDFs, 2) controlling subcategories to determine present activities and sources in the country, 3) collection of detailed information on the processes and classifying processes into similar ...
In preparation for a study of the relative oral bioavailability of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in soils (typically containing less than 1 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD] toxic equivalents [TEQ]), the background concentrations of PCDD/ Fs and selected polychlorinated biphenyls (PCBs) were measured in liver and adipose tissue from female Sprague-Dawley rats and juvenile swine after 30 d of ingesting laboratory chow. The measured concentrations of TCDD and other PCDD/Fs in rat livers were severalfold less than previously reported in the literature for control (unexposed) laboratory rodents. The concentrations of PCDD/Fs and selected PCBs in livers of swine were three- to fourfold lower than those reported for rats. The lower concentrations found in this study compared to previous findings may be due to inadvertent laboratory contamination in previous studies or to declining levels of PCDD/Fs in laboratory feed, which parallel the declines in ...
MONDAY, Dec. 30, 2019 (HealthDay News) -- Decades-banned pesticides apparently continue to interfere with fetal growth during U.S. pregnancies, a new study reports.. DDT was banned in 1972 in the United States, but low levels of it and other organic chemical pollutants can still be found in the blood of pregnant American women, researchers reported online Dec. 30 in JAMA Pediatrics.. Women carrying even low levels of these pollutants had slightly smaller fetuses than women whose exposure to the chemicals was less, results showed.. The most consistent effects seemed to come from DDT and related pesticides, said study co-author Pauline Mendola, an investigator at the U.S. National Institute of Child Health and Human Development.. Bones seem to be more affected, she said. Head circumference and femur length were more often impacted than other growth measures.. This study looked at persistent organic pollutants -- chemicals once used in agriculture, pest control, manufacturing and industrial ...
MONDAY, Dec. 30, 2019 (HealthDay News) -- Decades-banned pesticides apparently continue to interfere with fetal growth during U.S. pregnancies, a new study reports.. DDT was banned in 1972 in the United States, but low levels of it and other organic chemical pollutants can still be found in the blood of pregnant American women, researchers reported online Dec. 30 in JAMA Pediatrics.. Women carrying even low levels of these pollutants had slightly smaller fetuses than women whose exposure to the chemicals was less, results showed.. The most consistent effects seemed to come from DDT and related pesticides, said study co-author Pauline Mendola, an investigator at the U.S. National Institute of Child Health and Human Development.. Bones seem to be more affected, she said. Head circumference and femur length were more often impacted than other growth measures.. This study looked at persistent organic pollutants -- chemicals once used in agriculture, pest control, manufacturing and industrial ...
NTP Experiment-Test: 96007-05 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04 Study Type: CHRONIC TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) Date: 07/14/03 Route: GAVAGE Time: 14:46:46 31 WEEK SSAC RATS Facility: Battelle Columbus Laboratory Chemical CAS #: 57117-31-4 Lock Date: 07/25/02 Cage Range: All Reasons For Removal: 25017 Scheduled Sacrifice Removal Date Range: 11/03/99 - 11/04/99 Treatment Groups: Include All Note: Animals arranged according to CID number Page 1 NTP Experiment-Test: 96007-05 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04 Study Type: CHRONIC TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) Date: 07/14/03 Route: GAVAGE Time: 14:46:46 __________________________________________________________________________________________________________________________________ , 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, , , DAY ON TEST , 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, , , , 2, 1, 1, 1, 1, 1, 2, 2, 2, 2, 1, 1, 1, 1, 1, 2, , , ...
Dioxin. Computer model of a molecule of the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Atoms are represented as spheres and are colour-coded: carbon (lilac), chlorine (green), hydrogen (white) and oxygen (red). Dioxins are a family of toxic by-products of a number of industrial processes, including burning waste, heating metals and bleaching paper and textiles. They have no industrial use themselves. They are persistent organic pollutants (POPs) and build up over time in living tissue (bioaccumulation). Long-term high-level exposure can cause birth defects, cancer and a higher risk of diabetes. TCDD is one of the most toxic of the dioxins. - Stock Image A654/0038
Residents from a San Jacinto riverfront community stood together on Tuesday to express concern that one of the most polluted properties in Harris County could be breached by a storm, spreading dioxin contamination widely. Dioxins, which some health experts consider the most toxic compounds created by man, are heavily present in the sediments of the San Jacinto River near the community of Highlands, where two former paper plants dumped waste into pits. The location of these industrial dump sites had been forgotten for years until Texas parks and wildlife officers, looking for the source of dioxins in Galveston Bay, rediscovered the partially underwater pits in 2005. According to the Environmental Protection Agency, International Paper is the company responsible for the actions of Champion Paper, which generated the pulp-related waste. Waste Management was not affiliated with MIMC during that period, never operated MIMC, never owned the San Jacinto River Waste Site property and was never involved in
In response to the recent discovery of dangerous levels of dioxins in animal feed produced in Germany, Phenomenex has announced its publication of a method for analysing the chemicals using high-resolution gas chromatography with mass spectrometric detection.
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ultra-trace levels.
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ultra-trace levels.
After the Japan disaster, the workers undergoing the task of clearing millions of tonnes of debris face threats from asbestos and dioxins.
Get the latest dioxins removal (air and climate) news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
There have been many studies about dioxin but there is a lot that we do not know about how dioxin affects people. For example, we do not know how much dioxin affects a person or how long a person has to be exposed for before they are affected. Animal studies show cancer, immune, reproductive, and developmental effects but the evidence of non-cancer effects in people is limited.. The most well studied dioxin is called 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In animal research, dioxin seems to be a strong promoter (helps it along) and weak initiator (starter) for the development of cancer. This means that cancer development following dioxin exposure may depend on other causes of cancer like tobacco use.. The Institute of Medicine of the National Academy of Sciences in the United States of America regularly reviews the evidence about dioxin exposure and health. It makes a list of conditions that it accepts as being associated with dioxin exposure. It accepts the following conditions as being ...
The CYP1A1 and CYP1B1 genes are members of aromatic hydrocarbon receptor battery genes. The expression of these genes, therefore, is thought to be induced concomitantly through the activation of aromatic hydrocarbon receptor. In agreement with this concept, both CYP1A1 and CYP1B1 mRNAs were induced by the treatment of human blood monocytes with dioxins or PAHs in vitro (11 , 12) . The subjects whose leukocytes were analyzed in this study were workers occupationally exposed to dioxins at waste incinerators (9) . Thus, we expected that both CYP1A1 and CYP1B1 mRNAs might be induced by environmental exposure to dioxins. However, we found that the expression of only CYP1B1 mRNA was induced, whereas the expression of CYP1A1 mRNA was not induced. The reason accounting for the fact that only CYP1B1 mRNA was induced is not known at present.. After the first report on the significant association between AHH inducibility in human lymphocytes and the bronchogenic cancer risk (3) , many papers have appeared ...
One study conducted by the Environmental Protection Agency discovered that human fat cells contain dioxin and traces of four solvents. Whats more, 90 percent of them included three more dioxins, while 83 percent PCBs (industrial chemicals).. Dioxins are chemicals dangerous for your health, formed during combustion, as well as pulp bleaching and other industrial processes.. They can cause a wide range of health complications, so the body stores them in fat cells to prevent them from roaming free and causing organ damage. Bit, this leads to another serious problem.. The first thing to understand is that toxins can be fat-, or water-soluble. They include different pesticides, preservatives, food additives, plastics, pollutants, and heavy metals.. Now, the next thing is the function of bile. This liver fluid breaks down fat and removes old erythrocytes (red blood cells) from the body.. The gut is permeable during digestion, allowing the lymph to identify absorbed fat and take it to the liver for ...
In 1996, dioxins were discovered in ball clay as a result of an investigation to determine the sources of elevated dioxin levels in two chicken samples from a national survey of poultry. The investigation indicated that the contamination source was ball clay added to chicken meal as an anti-caking agent. The purpose of this study was to evaluate another potential exposure scenario associated with ball clay, namely its use in ceramic art studios. This exploratory investigation makes preliminary exposure estimates that can be used to evaluate whether more detailed follow-up analyses will be needed ...
Dioxins and PCBs can be carcinogenic at minimal here levels of exposure eventually. These substances are determined and measured in a single of two classes, dioxin-like PCBs and full PCBs. Even though the U.S. FDA has not established a limit for PCBs in supplements, the worldwide Business for EPA and DHA (GOED) has founded a guideline making it possible for for no more than three picograms of dioxin-like PCBs for each gram of fish oil ...
en] Among the different analytical tools proposed as an alternative to the very expensive gas chromatography high-resolution mass spectrometry (GC-HRMS) analyses of polychlorodibenzo-p-dioxin and polychlorodibenzofurans, Chemically Activated LUciferase gene eXpression (CALUX) in vitro cell bioassay is very promising. It allows the analyses of a high number of samples since it is relatively fast, inexpensive, and sensitive. However, this technique is not yet widely applied for screening or environmental monitoring. The main reasons are probably the lack of validation and the difficulty in interpreting the global biological response of the bioassay. In this paper, the strict quality control criteria set up for the validation of CALUX are described. The validation has shown good repeatability (relative standard deviation (RSD) = 9%) and good within-lab reproducibility (RSD = 15%) of the results. The quantification limit, in the conditions applied in this paper, is 1.25 pg CALUX-TEQ/g fat. ...
In the northwestern Icelandic town of Isafjordur, milk is causing pandemonium. A local milk marketing board recently tested one farms milk for the presence of harmful chemicals. Dioxin, and dioxin-like compounds, were found to be present in amounts higher than the recommended maximum levels, threatening the future of local farmers, and angering residents.
sam wrote: ---- Food for thought: PVC production has almost tripled in the last fifteen years. Yet, dioxin exposure has dropped by over 75% in the last decade; I am talking the total biologically available as a function of TEQ. Seems to me that if the PVC industry was the smoking The reports on dioxin exposure are independent university research efforts or government studies (US and Europe), *not* from the PVC industry. ---- aside from phillips response questioning the 75% drop in exposure; as to pvc sources contribution we need to look at a more complete picture than what gp has managed to extract from that industry. pcdd/f attributable to pvc come from the complete life cycle, not just the pcdd/f produced at the pvc & edc plants. and since pvc production skyrocketed only recently, how much of the increase has gone through its life cycle and been incinerated? also, a certain fraction of pcdd/f created at production will not contribute to exposure for a long time (ie that portion landfilled, as ...
Of course, paper has many uses. Its everywhere; books, newspapers, wallpaper, lampshades, cups, plates, paper bags, hats, insulation, filters, toilet paper, kites, playing cards, origami. It has been a transformative material.The downside is that paper production is a massive, global polluter on land, water and air. It is the third largest industrial, polluter in North America, the fifth biggest user of energy and uses more water per ton of product than any other industry.Paper in landfill sites accounts for around 35% of all waste by weight. Recycling helps but even the deinking process produces pollutants. Paper production still uses chlorine and chlorine based chemicals and dioxins are an almost inevitable part of the paper production process. Water pollution is perhaps the worst, as pulp mill waste water contains is oxygen hungry and contains an array of harmful chemicals and harmful gases and greenhouse gases are also emitted. It may seem as though reforestation is a plus, but these are ...
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Polychlorinated dioxins, dibenzofurans (PCDD/PCDF) and polychlorinated biphenyls (PCBs), are persistent organic pollutants (POPs) that bioaccumulate in lipids and may enter the food chain through animal products. Recently, Polish authorities discovered a free range farm whose eggs exceeded national standards for dioxin contamination two-fold. Piskorska-Pliszczynska et al.1 evaluated samples from that farm to determine the likely source of the dioxin exposure and to quantify the bioaccumulation of PCDD/Fs and PCBs in the tissues and eggs of the affected hens. They took specimens from the commercial feed and the soil of the free range areas. A veterinarian also performed necropsies and sampled muscle, abdominal fat, liver tissue, ovarian follicles, and whole eggs present in the oviducts. The researchers identified 35 PCDD/F and PCB congeners of interest, including dioxin-like polychlorinated biphenyls (DL-PCBs) and non-dioxin-like polychlorinated biphenyls (NDL-PCBs), using gas chromatography ...
Dive into the research topics of Development of toxic equivalency factors for PCB congeners and the assessment of TCDD and PCB mixtures in rainbow trout. Together they form a unique fingerprint. ...
Free Public Domain Picture: U.S. Ambassador David B. Shear speaks at the Environmental Remediation of Dioxin Contamination at Danang Airport Project Launch | ID: 13989043215339
Figure 6: Hypothetical diagrams of the effect of Bakumondo-to. (a) After ligation of dioxins to the AhR, the receptor translocates from the cytosol to the nucleus, binds to DRE, and activates transcription of CYP1A1, mucin and other genes in bronchiolar Clara cells. Excess mucin production from Clara cells by dioxins is supposed to be responsible at least in part for respiratory symptoms of Yusho patients. (b) Active ingredients in Bakumondo-to would block activation of the AhR by competitive interference with the interaction between dioxins and the AhR, and inhibit transcription of mucin in Clara cells, leading to improvement of respiratory symptoms of Yusho patients ...
Dioxins and dioxin-like chemicals are predominantly produced by thermal processes such as incineration and combustion at concentrations in the range of 10-100 ng of I-TEQ/kg (I-TEQ = international toxic equivalents). In this work, a new approach for the removal of dioxins from high-temperature vapor streams using facilitated supported ionic liquid membranes (SILMs) is proposed. The use of ceramic membranes containing specific ionic liquids, with extremely low volatility, for dioxin removal from incineration sources is proposed owing to their stability at very high temperatures. Supported liquid membranes were prepared by successfully immobilizing the ionic liquids tri-C₈-C₁₀-alkylmethylammonium dicyanamide ([Aliquat][DCA]) and 1-n-octyl-3-methylimidazolium dicyanamide ([Omim][DCA]) inside the porous structure of ceramic membranes. The porous inorganic membranes tested were made of titanium oxide (TiO₂), with a nominal pore size of 30 nm, and aluminum oxide (Al₂O₃), with a nominal ...
Persistent organic pollutants (POPs) are fat soluble chemical substances that persist in the environment and bioaccumulate in the food chain. Through long-range environmental transportation by air, water and migratory species they are transferred to new locations distant from the source of release and might cause adverse effects to human health and to the environment. POPs comprise pesticides, industrial chemicals and unwanted by-products. The European Commission has implemented food and feed legislations concerning maximum permitted levels (MPLs) of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs), dioxin-like polychlorinated biphenyls (DLPCBs), polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs). Fish and consequently fishmeal and fish oil has been identified as one of the most important contributors to the level of dioxins and DL-PCBs in food and feed products. Fish caught in some of the North-European fishing areas contain high dioxin and PCB levels resulting ...
Polychlorinated dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls are persistent environmental pollutants which ubiquitously occur as complex mixtures and accumulate in the food and feed chain due to their high lipophilic properties. Of the 419 possible congeners, only 29 share a common mechanism of action and cause similar effects, the so called dioxin-like compounds. Dioxin-like compounds evoke a broad spectrum of biochemical and toxic responses, i.e. enzyme induction, dermal toxicity, hepatotoxicity, immunotoxicity, carcinogenicity as well as adverse effects on reproduction, development, and the endocrine system in laboratory animals and in humans. Most, if not all, of the aforementioned responses, are mediated by the aryl hydrocarbon receptor. In the present work, the elicited biochemical effects of a selection of dioxin-like compounds and the non dioxin-like PCB 153 were examined in mouse (in vivo) and in human liver cell models (in vitro). Emphasis was given to the main ...
The United States Environmental Protection Agency (US EPA) has been in the process of conducting a reassessment of the health damaging effects of dioxin exposure for the past decade. In 2000, the agency published a draft risk characterization that attributed a 1 in 1000 upper-bound excess cancer risk to average background levels of dioxin exposure.. Several federal government agencies, including: the US Department of Agriculture, the US Food and Drug Administration, the US Department of Health and Human Services, and the EPA, are represented on the Interagency Working Group on Dioxin. These parties have developed a paper entitled Questions and Answers About Dioxins that provides basic information for the public on the matter of exposure and adverse health effects.. The Institute of Medicine (IoM) published, Dioxins and Dioxin-Like Compounds in the Food Supply: Strategies to Decrease Exposure , in 2003. The critical message of this report is that current levels of dioxins and dioxin-like ...
The polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), popularlycalled dioxins, are persistent pollutants with widespread occurrence in the environment aswell as in human food and tissues. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the mosttoxic dioxin, as well as other dioxin-like compounds induce a broad spectrum ofbiochemical and toxic effects, many of which occur at extremely low doses orconcentrations. Thus, there is a great need for an appropriate human health riskassessment However, due to several uncertainties, such as species differences in sensitiviyand the great number of dioxin-like compounds, it is urgent that the mechanisms behindthe toxic effects which are critical for human low-dose exposure are elucidated, i.e., effectson reproduction, fetal development, immune function, and tumour development. Theessential nutrient vitamin A, which acts as a hormone, is needed for proper reproduction,development, immune function, and can also affect tumour development. In ...
Boys had been recruited at age 8 or 9 years, and pubertal stage was assessed yearly based on testicular volume and genital maturity according to the Tanner Stages, a scale of physical development. Both the boys and their mothers provided blood samples for genetic and contaminant analyses at the study outset, and health, lifestyle, and diet data were collected through questionnaires.. Previous analyses had indicated that serum concentrations of dioxins and dioxin-like compounds were associated with later pubertal onset among these boys. The current study, conducted when the boys had reached age 12 or 13 years, investigated whether genetic variations modified this outcome.. The investigation included 392 boys and involved 337 SNPs identified in 46 genes and 2 intergenic regions (stretches of DNA between protein-coding genes) that may influence pubertal onset or the biological response to dioxins. The association of serum dioxins with later pubertal onset was confirmed, and two statistical methods ...
You probably havent heard anything about this group of toxic chemicals for almost six years. Formed during combustion processes such as waste incineration, theyre known to increase the likelihood of cancer after long-term low level exposure. At higher levels, dioxins can be disfiguring or deadly. It was six years ago that the world first saw a clear example of the damage that dioxins can cause. The face of former Ukrainian President Viktor Yushchenko was heavily scarred, the effect of a chloracne outbreak after suspected dioxin poisoning. He might have been poisoned with as little as a drop and significant amounts of poison could remain in his system for the rest of his life. Wikipedia paints a much scarier portrait of the 70+ isomers of highly toxic, man-made organic compounds. Byproducts of some industrial processes and waste incineration, dioxins are fat-soluble, so they tend to accumulate in the tissues of the animals who encounter them and it can take many years for the compounds to ...
Epidemiological studies suggest that exposure to persistent organic pollutants such as organochlorines might induce cardiovascular disorders and diabetes. Some of these organochlorines, such as dioxins and some dioxin-like PCBs, have been characterised as anti-estrogenic due to their inhibition of estrogenic-induced responses. In the present pilot study, 40 female rats were subjected to either exposure to the dioxin-like 3,3,4,4,5-pentachlorobiphenyl (PCB 126) or vehicle, as well as ovariectomy (OVX) or sham operation in a 2 x 2 factorial design over 12 weeks to explore potential interactions between estrogen status and PCB 126 exposure on cardiovascular risk factors. PCB 126 increased heart weight and serum cholesterol levels in both groups. PCB 126 increased blood pressure in the sham-operated animals only. In conclusion, PCB 126 exposure in female rats resulted in effects on cardiovascular risk factors, such as serum cholesterol, blood pressure, and heart weight. Of these effects of PCB ...
Johns Hopkins has recently sent this out in its newsletters. This information is being circulated at Walter Reed Army Medical Center as well. Dioxin chemicals causes cancer, especially breast cancer. Dioxins are highly poisonous to the cells of our bodies. Dont freeze your plastic bottles with water in them as this releases dioxins from the plastic. Recently, Dr. Edward Fujimoto, Wellness Program Manager at Castle Hospital , was on a TV program to explain this health hazard. He talked about dioxins and how bad they are for us.. He said that we should not be heating our food in the microwave using plastic containers. This especially applies to foods that contain fat. He said that the combination of fat, high heat, and plastics releases dioxin into the food and ultimately into the cells of the body. Instead, he recommends using glass, such as Corning Ware, Pyrex or ceramic containers for heating food. You get the same results, only without the dioxin. So such things as TV dinners, instant ramen ...
Toxic dioxins and furans can accumulate through industrial processes. SGS dioxin and furan analysis can accurately measure trace quantities to improve your site safety. Find out more.
So far we have looked at the disturbing unreliability of the existing pro-TDF studies, the special problems posed by burning tires in paper mill boilers, and the alarming lack of knowledge about a wide range of potential dangers that tire incineration may pose to the health and safety of our communities and the environment. This next section will take a closer look at the existing record and find that even based on the limited knowledge that exists, it is already clearly evident that tire incineration is dangerous.. Below is a breakdown of some of the condemning test data, organized by chemical groupings:. Dioxins and Furans. Dioxins are highly toxic and cause serious health problems, including infertility, learning disabilities, endometriosis, sexual reproductive disorders, birth defects, damage to the immune system and cancer. Dioxin is fat-soluble and once its released into the outside environment, it readily climbs up the food chain, causing average meat and dairy-product consumers to get ...
The Formosa Plastics Corporation plant is located near Illiopolis, between Springfield and Decatur along I-72. On April 23, 2004, an explosion occurred at the plant followed by a fire that burned for several days. Illinois EPA, along with other agencies, have worked to test air quality during and after the fire, water quality in creeks and streams near the site and the safety of the drinking water supply. Illinois EPA will continue to have a long-term presence at the site in the form of oversight regarding site investigation and proper cleanup of contamination.. Dioxins and other chlorinated chemicals may have been formed during the smoldering phases of the fire at the plant. A few initial samples were taken to test for dioxins on the site. In addition, initial sampling of 13 public and private properties was performed on June 30, 2004 by Formosa, with oversight by Illinois EPA. The results of those screening samples showed the presence of low levels of dioxins. Illinois EPA requested that ...
INTERNATIONAL. IARC releases monograph on benzene. OECD…. …Draft test guidelines. …Risks of mixed exposures. …Validation studies of two in vitro test methods (skin corrosion and eye irritation). …Updated reporting templates. JECFA reports on food contaminants. WHO Expert Committee on Drug Dependence reviews a range of drugs including cannabis. EUROPE. REACH…. …Member State Committee (MSC) deliberations on substances of very high concern (SVHCs). …Draft recommendation for authorisation list. …Testing proposals involving vertebrate animals. …ECHA to derive occupational exposure limits. Classification and labelling…. …Proposal for harmonised classification and labelling. …RAC opinions on harmonised classification and labelling. Biocidal Products Regulation. …BPC opinions on seven active substances. EFSA…. …Evaluation of propylene glycol esters of fatty acids as a food additive. …Consideration of dioxins and dioxin-like polychlorinated biphenyls. …Assessment of ...
July 25, 2014. By Marie Zhuikov. Researchers already know that dioxin (a byproduct of burned plastics and industrial processes) is toxic and can contribute to cancer and heart problems in humans, but now they know it can impact a fishs nose tissue. Why should we care? Because fish use their noses to navigate through water and to find streams for spawning.. Wisconsin Sea Grant-funded researcher, Michael Carvan, Shaw associate scientist at the University of Wisconsin-Milwaukee School of Freshwater Sciences, has been studying the impacts of dioxin on rainbow trout (Oncorhynchus mykiss) and zebrafish (Danio rerio). Although zebrafish are not a Great Lakes species like the trout, researchers use them because they are a hardy lab fish about which much is known.. Carvan and his research team fed both young rainbow trout and zebrafish food containing different levels of TCDD (tetrachlorodibenzo-p-dioxin) over a six-week period. They chose to work on juvenile fish because few studies for dioxin exposure ...
in Accreditation and Quality Assurance (2006), 11(1-2), 38-43. In the determination of contaminants (dioxins, polychlorinated biphenyls, polyaromatic hydrocarbons), cell-based assays are useful methods for screening purposes: they are mainly characterized by high ... [more ▼]. In the determination of contaminants (dioxins, polychlorinated biphenyls, polyaromatic hydrocarbons), cell-based assays are useful methods for screening purposes: they are mainly characterized by high sample throughput and lower costs than the Mass Spectrometry (MS)-based methods. Although cell-based assays can be sensitive enough for the determination of dioxins and related substances in agreement with the presently tolerable limits in food and feed (Regulation No. 2375/2001/EC and Directive 2003/57/EC respectively), their lack of specificity make their use rather questionable in control laboratories. In this paper, we present and compare results obtained from the analysis of a limited number of feed samples by both gas ...
The Department continued to work in the Urban Rivers Team. The team focuses on the Woonasquatucket River until priority issues such as dioxins are controlled.. The Woonasquatucket River watershed encompasses most of the Town of Smithfield as well as parts of North Smithfield, Glocester, Johnston, and Providence. The 18 mile river arises in a rural area, flows into increasingly urbanized territory and ends at Waterplace Park in Providence. The River suffers from the cumulative impacts of industrial contaminants such as dioxins and PCBs in urban stretches. Other problems include excess nutrient loading, abandoned industrial sites, litter and illegal dumping of solid waste. While some stretches of the urban river bank are surprisingly healthy, others are degraded and provide poor habitat.. In 1999, the Department began work with the American Heritage River Steering Committee, the Urban Rivers Team, and the USEPA River Navigator to coordinate watershed efforts and to produce a State of the Watershed ...
PVC produces HCl upon combustion almost quantitatively related to its chlorine content. Extensive studies in Europe indicate that the chlorine found in emitted dioxins is not derived from HCl in the flue gases. Instead, most dioxins arise in the condensed solid phase by the reaction of inorganic chlorides with graphitic structures in char-containing ash particles. Copper acts as a catalyst for these reactions.[55] Studies of household waste burning indicate consistent increases in dioxin generation with increasing PVC concentrations.[56] According to the EPA dioxin inventory, landfill fires are likely to represent an even larger source of dioxin to the environment. A survey of international studies consistently identifies high dioxin concentrations in areas affected by open waste burning and a study that looked at the homologue pattern found the sample with the highest dioxin concentration was typical for the pyrolysis of PVC. Other EU studies indicate that PVC likely accounts for the ...
PVC produces HCl upon combustion almost quantitatively related to its chlorine content. Extensive studies in Europe indicate that the chlorine found in emitted dioxins is not derived from HCl in the flue gases. Instead, most dioxins arise in the condensed solid phase by the reaction of inorganic chlorides with graphitic structures in char-containing ash particles. Copper acts as a catalyst for these reactions.[54]. Studies of household waste burning indicate consistent increases in dioxin generation with increasing PVC concentrations.[55] According to the EPA dioxin inventory, landfill fires are likely to represent an even larger source of dioxin to the environment. A survey of international studies consistently identifies high dioxin concentrations in areas affected by open waste burning and a study that looked at the homologue pattern found the sample with the highest dioxin concentration was typical for the pyrolysis of PVC. Other EU studies indicate that PVC likely accounts for the ...
For those of you w/ WWW access, check it out at http://www.epa.gov/OST/fishadvice/facts.html Heres teh text (w/out the cool maps) The Alliance for Environmental Technology is, of course, highlighting this part: ...The total number of advisories for dioxins was 54 in 1993, then rose to 63 in 1994, held steady at 63 in 1995, and declined to 60 advisories in 1996. Dioxins are one of several chemical contaminants for which advisories have been rescinded by some states, in part because many pulp and paper mills have changed their processes. ... Note that we in MN lead the U.S, pack w/ 709 -- 693 due to mercury! ================ United States Environmental Protection Office of Water EPA-823-97-007 Agency Mail Code 4305 June 1997 ---------------------------------------------------------------------------- [Image] Fact Sheet Update: Listing of Fish and Wildlife Advisories Summary The 1996 update for the database, Listing of Fish and Wildlife Advisories (LFWA), is now available from the U.S. ...
Summary/Abstract The aryl hydrocarbon receptor (AhR) is known for mediating the toxicity of environmental pollutants such as dioxins and numerous dioxin-like compounds. Due to the widespread occurrence in our environment and the high toxic potential, these contaminants are of concern to promote malignancies including breast cancer. More recently it has been found that the AhR may also act as a critical receptor protein in tumor promotion independent from exogenous ligands, which is based on immune tolerance and increased survival in cancer cells. Consequently, the AhR has emerged as an attractive target for new drugs in cancer therapy. Furthermore, the AhRs action is restricted by a specific repressor protein, the AhR Repressor (AhRR). The AhRR is a ligand-independent, transcriptionally inactive AhR-like protein and is thought to repress AhR signaling. While AhRR effectively blocks AhR, the role of AhRR as a tumor suppressor gene is only poorly understood. We established a transgenic mouse ...
Dioxins are found in meat, poultry, fish and even in milk. In just six months of breast feeding, a baby in the U.S. will, on average, consume the EPAs maximum lifetime dose of dioxin.1 these toxins get passed on to humans from the plants animals eat. They are stored in the fatty tissues and then we n turn eat it. Then it stores in our fat, and creates a build-up.. Of course we are all digesting these poisons, but if you look through the Canadian Cancer Statistics for 2011, featuring a study on Colorectal Cancer, produced by the Canadian Cancer Society, it says, The estimated incidence rates for all cancers combined continue to be highest for the maritime provinces and Quebec and lowest in British Columbia.2 Its easy enough to why this is, when you take the north-west prevailing winds into consideration. Based on current incidence rates, 40% of women and 45% of men in Canada will develop cancer during their lifetimes. But this expectancy increases the farther east you live.. Watch this ...
Svante Arrhenius väg 8, Stockholm. Arrheniuslaboratoriet, Svante Arrhenius väg 16, Stockholm (Unit for Analytical and Toxicological Chemistry). Mailing address: ...
The fact that the molecular mechanisms of dioxin toxicity are still poorly understood complicates dioxin risk assessment. Only one mechanism of dioxin action, the direct induction of CYP1A1, has been elucidated in detail (5). However, despite its direct regulation by the AHR, CYP1A1 induction is not predictive of dioxin toxicity.. A useful tool for studying the mechanisms of dioxin toxicity is the large sensitivity difference in TCDD-induced lethality between H/W and L-E rat strains. Although there is a large sensitivity difference in certain endpoints of TCDD toxicity (e.g. acute lethality, wasting, and hepatotoxicity), other responses, such as induction of CYP1A1, remain similar between these strains (3). A wide range of clinical chemistry variables and biochemical parameters have been investigated in an effort to rationalize the differences between these two strains, but no clear molecular factors responsible for TCDD resistance in the H/W rat strain have been identified.. The aim of this ...
Postdoctoral Training, Harvard Medical School. BUMC Research Profile. Recent studies have demonstrated that a number of common environmental pollutants (i.e. aromatic hydrocarbons, dioxins, PCBs) compromise the immune system as well as induce cancer. Like immunosuppressive therapeutics (e.g. steroids), these compounds induce thymic atrophy, decrease resistance to infectious agents and transplantable tumors, reduce bone marrow cellularity, alter lymphocyte homing, impair B cell antibody responses, decrease cytotoxic T cell activity, inhibit natural killer activity and decrease cytokine production. Immunotoxicity mediated by extremely low concentrations of environmental pollutants is regulated by an intracellular aromatic hydrocarbon receptor (AhR) which, when bound by hydrocarbons, dioxins, or PCBs, translocates to the nucleus, activates gene promoters, and induces transcription of a number of genes including proto-oncogenes and cytokine genes. Although the endogenous AhR ligand is unknown, work ...
Adhere to stringent environmental regulation with our comprehensive range of reference materials for dioxin & furan testing. 500+ products available online.
Fish with the high levels of dioxins are Baltic herring, Baltic salmon and Baltic sprats.. Under EC regulations that came into force on January 1 last year, the area in which fish are caught must now be specified.. Sweden and Finland have undertaken not to sell their fish to other European countries and, where they are still selling their fish domestically, health authorities must issue warnings to women of child-bearing age against regularly eating Baltic salmon or herring. Other consumers are being warned not to eat oily fish from the Baltic more than once a week. ...
One long-running battle centers on Mossville, a small African-American community founded in the 1790s across from Lake Charles, La.. Fourteen major industrial facilities surround the community, including an oil refinery, a coal plant, chemical manufacturers and one of the largest clusters of vinyl production facilities in the United States.. For 15 years, residents have been asking government and industry to relocate them from the powerful odors and toxic chemicals released by the plants, citing reports showing dangerous levels of dioxins in the air. Dioxins, researchers say, can cause cancer and reproductive damage and slow child development.. In 1998, the federal Agency for Toxic Substances and Disease Registry found that Mossville residents had an average dioxin blood level three times above that in the typical U.S. community.. The report, however, did not identify the source of the exposure. A later ATSDR report said residents in the neighboring parishes of Calcasieu and Lafayette had ...
More and more people are aware that eating certain types of seafood can increase your exposure to mercury, PCBs, dioxins and pesticides. Industrial activities have significantly elevated the amount of mercury and other toxics chemicals in the environment. Present in the air and water, these contaminants have made their way into some of the food we eat.. Mercury in fresh and marine waters is converted by bacteria into methylmercury, which is easily absorbed by animals as they feed and binds to fish protein. Methylmercury and persistent organic compounds, such as dioxins and PCBs, accumulate in fish tissue and become concentrated in fish high on the food chain. Residues of antibiotics and hormones used in aquaculture may be a cause for additional caution. However, there are still many seafood options that allow people to get the benefits of seafood without the risk of contaminants.. Health Canada, the U.S. Food and Drug Administration and the U.S. Environmental Protection Agency all issue warnings ...
Exposure to chlorinated dibenzo-p-dioxins (CDDs) (75 chemicals) occurs mainly from eating food that contains the chemicals. One chemical in this group, 2,3,7,8-tetrachlorodibenzo-p-dioxin or 2,3,7,8-TCDD, has been shown to be very toxic in animal studies. It causes effects on the skin and may cause cancer in people. This chemical has been found in at least 91 of 1,467 National Priorities List sites identified by the Environmental Protection Agency (EPA).
BKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. http://europa.eu.int/comm/environment/docum/01262_en.htm#bkh. Category 1 chemicals from Annex 1: Candidate list of 553 substances. http://europa.eu.int/comm/environment/docum/bkh_annex_01.pdf, Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998., Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. ...
Nicole Lozzi is a graduate student in law at the Catholic University of Piacenza (Italy), studying the Agro-food System (Agrisystem Doctoral School). Her research interests include food safety and food alerts in Europe and the United States. She became interested in comparing the legal and policy choices that form the basis for the current agrofood safety systems through observing several cases of food emergencies of public concern that occurred recently in Europe, including BSE, dioxin contamination, and bird flu.. ...
PVC is everywhere - in our houses, in our childrens toys, in the air and most concerning- in our food. Low exposures to dioxins from the manufacture and disposal of PVC cause mutations thus tumors in our bodies. Any molecule that is present in our bodies poses a risk of cancer. As a doctor from Columbia University said on the film: Zero exposure is best. Dioxins affect EVERYONE - not only those who live near the factories that create PVC (i.e. Lake Charles, Louisiana and Venice, Italy). PVC is the worst plastic from an environmental health perspective, posing great environmental and health hazards in its manufacture, product life and disposal. - MyHouseIsYourHouse.org (My House is Your House is the consumer education and advocacy campaign tied to Blue Vinyl.) ...
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The objective of this research project is to determine whether exposure to dioxins, a byproduct of industrial processes and an environmental contaminant, is associated with altered growth and sexual maturation in boys. Specific objectives include exploring whether physical growth is delayed and stunted, whether sexual maturation is delayed, and whether reproductive hormones are altered. Dioxin levels will be measured in blood samples drawn from the boys and their mothers. Yearly physical examinations will be performed to assess growth velocity and onset and tempo of sexual maturation. Questionnaire data will be collected on birth and medical history, as well as lifestyle factors. Statistical modeling will be used to explore the relationship between serum levels of dioxin and altered physical growth and sexual maturation.. ...
This video is an introduction to the United Nations Environment Programmes Dioxin Toolkit (2013). It offers a brief history of the Toolkit, including its relationship to the Stockholm Convention, and a step-by-step search of the Toolkit for information on identifying sources of dioxins and other unintentional POPs addressed by the Convention.. The presenter in the video is Pat Costner, B.S., M.S., who worked with IPEN primarily via IPENs Dioxin, Waste and PCBs Working Group. Ms. Costner was a member of the Stockholm Conventions Toolkit Expert Group, a Senior Scientist with Greenpeace, and a Science Advisor for the Global Alliance for Incinerator Alternatives (GAIA).. ...
柴油車排氣中戴奧辛控制技術與焚化爐產生戴奧辛的人體暴露之研究. Treatment Effectiveness of Dioxin Emission from Diesel Engine and Human Exposure from Exhaust of Incinerator. ...
The European Food Safety Authority has published a new report on levels of dioxins and polychlorinated biphenyls (PCBs) in food and feed. Canada Environment Siskinds LLP 16 Aug 2012
In 2012, the Texas Department of State Health Services delivered its public health assessment of dioxin in the waste pits. The report again warned of hazards posed to fish, but it dismissed the idea of contamination in neighborhoods soil or well water.. Rifai said UHs studies of river water and sediment could not be used to determine whether yards, parks or well water was safe. She is now working with the Galveston Bay Foundation, an independent nonprofit, and Harris County to conduct more testing after Harveys flooding.. The Matulas have two wells on the cottage property. For decades, they drank from the older, shallow well. About 10 years ago, they dug a deeper one.. After Sean Matula paid for testing, he asked state health officials to review the complex lab reports. They found dioxin in the older well to be more than twice what the EPA considers dangerous for humans of any age to drink. Dioxin levels in the newer well represented an increased risk of cancer for children and adults but ...
Aryl Hydrocarbon Receptor, Human, Health, Hormone, Luciferase, Estrogen, Humans, Phytoestrogens, Environment, Food, Inuit, Transactivation, Cell, Cells, Gene, Reporter Gene, Concentration, Bioassay, Dioxins, Pesticides
Quantification of PCDD/Fs and dioxin-like PCBs in small amounts of human serum using the sensitive H1L7.5c1 mouse hepatoma cell line: Optimization and analysis of human serum samples from adolescents of the Flemish human biomonitoring program FLEHS IICROESA, K; VAN LANGENHOVE, K; VAN LAREBEKE, N et al.Talanta (Oxford). 2011, Vol 85, Num 5, pp 2484-2491, issn 0039-9140, 8 p.Article ...
According to the EPA dioxin inventory, landfill fires are likely to represent an even larger source of dioxin to the ... Rigo, H. G.; Chandler, A. J.; Lanier, W.S. (1995). The Relationship between Chlorine in Waste Streams and Dioxin Emissions from ... Dioxins[edit]. Main article: Polychlorinated dibenzodioxins. PVC produces HCl upon combustion almost quantitatively related to ... Instead, most dioxins arise in the condensed solid phase by the reaction of inorganic chlorides with graphitic structures in ...
Dioxin contamination[edit]. The company gained attention as a manufacturer of the chemical, 245 trichlorophenol, a precursor of ... Problems continued with dioxin emission from the works incinerator which burned residues from the chlorination plant. This ... An explosion in a pilot plant in 1968 had killed a chemist and spread dioxins over the debris. 79 employees contracted ... the river gained the dubious distinction of being the most polluted in the world with regard to dioxins, 27 times higher than ...
In addition, the transformation of TCS during manufacturing leads to the production of dioxins into aquatic habitats. Dioxins ... "Dioxins". National Institute of Environmental Health Sciences. Retrieved 2020-03-09. Odabasi, Mustafa; Elbir, Tolga; Dumanoglu ...
Dioxin easily accumulates in the food chain. Dioxin enters the body by attaching to a protein called the aryl hydrocarbon ... "Hội Nạn nhân chất độc da cam/dioxin Việt Nam" [Vietnam Association for Victims of Agent Orange/Dioxin]. vava.org.vn (in ... which contained traces of the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD was a trace (typically 2-3 ppm, ranging ... The project studied dioxin (TCDD) levels in blood as well as in adipose tissue in a small group of Vietnam veterans who had ...
... more commonly known as dioxins. The article found flaws in the EPA studies and concluded that much higher levels of dioxins ... "Large amounts of dioxin, a toxic byproduct of hexachlorophene, had been accidentally mixed with motor oil and sprayed on roads ... DuPont's DeLisle plant is one of three titanium dioxide facilities produce the most dioxins in the United States, according to ... Subra found higher levels of dioxin and chromium levels in sediment samples from the facility. ATSDR found that in 2004, " ...
Arnold Schecter, Thomas A. Gasiewicz (July 4, 2003). Dioxins and Health. pp. 145-160. Albert J. Mauroni (July 2003). Chemical ... and/or used Agent Orange during and decades after the 1948-1960 Malayan conflict suffered from serious exposure of dioxin. ...
... dioxins and dibenzofurans; formaldehyde; inorganic lead; mercury compounds; nickel; POM (including PAHs); and styrene. Gebel, T ...
The impurity, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was a suspected carcinogen that may have affected the health of over ... Arnold Schecter, Thomas A. Gasiewicz (4 July 2003). Dioxins and Health. pp. 145-160. Albert J. Mauroni (July 2003). Chemical ... the conflict suffered from serious exposure to dioxin and Agent Orange, which also caused major soil erosion to areas of Malaya ...
Many Commonwealth personnel who handled and/or used Agent Orange during the conflict suffered from serious exposure to dioxin ... Arnold Schecter, Thomas A. Gasiewicz (4 July 2003). Dioxins and Health. pp. 145-160. Albert J. Mauroni (July 2003). Chemical ...
They are considered as contributors to overall dioxin toxicity, and the term dioxins and dioxin-like compounds is often used ... The name Dioxin Affair was coined from early misdiagnosis of dioxins as the primary contaminants, when in fact they turned out ... PCBs that have dioxin-like activity are known to cause a variety of teratogenic effects in animals. Exposure to PCBs causes ... "Dioxin Dorms - SUNY New Paltz :: SUNY Dorm Tests Toxic :: By Eric Francis :: Published by Planet Waves". dioxindorms.com. ...
Food, particularly from animals, is the principal source of human exposure to dioxins. Dioxins were present in Agent Orange, ... Dioxins and Health. Dioxins and Persistent Organic Pollutants. 3rd. John Wiley & Sons. pp. 579-618. doi:10.1002/9781118184141. ... Dioxins are typically emitted from the burning of hospital waste, municipal waste, and hazardous waste, along with automobile ... Dioxins have been associated with several adverse effects in humans, including immune and enzyme disorders, chloracne, and are ...
Usually a mixture of dioxin-like compounds is produced, therefore a more thorough treatise is under dioxins and dioxin-like ... Tuomisto, Jouko (2019) Dioxins and dioxin-like compounds: toxicity in humans and animals, sources, and behaviour in the ... Dioxins and dioxin-like compounds Toxic Equivalency NIOSH Pocket Guide to Chemical Hazards. "#0594". National Institute for ... Because people are usually exposed simultaneously to several dioxin-like chemicals, a more detailed account is given at dioxins ...
NIEHS dioxin fact sheet. *"Dioxins and Dioxin-like Compounds in the Food Supply: Strategies to Decrease Exposure" Archived 2004 ... The word "dioxins" may also refer to other similarly acting chlorinated compounds (see Dioxins and dioxin-like compounds). ... See also: 2,3,7,8-Tetrachlorodibenzodioxin; Dioxins and dioxin-like compounds; and 1,4-Dioxin ... Dioxin exposure incidentsEdit. See also: Dioxin controversy. *In 1949, in a Monsanto herbicide production plant for 2,4,5-T in ...
A 2004 review of studies of dioxin and endometriosis concluded that "the human data supporting the dioxin-endometriosis ... doi:10.1016/S0002-9378(15)30003-X. Bruner-Tran KL, Yeaman GR, Crispens MA, Igarashi TM, Osteen KG (May 2008). "Dioxin may ... Guo SW (2004). "The link between exposure to dioxin and endometriosis: a critical reappraisal of primate data". Gynecologic and ... Environment: Environmental toxins (e.g., dioxin, nickel) may cause endometriosis. Müllerianosis: A theory supported by foetal ...
Dioxins break down slowly. It still threatens public health at low levels. Since industry has mostly stopped producing dioxins ... They continued to burn 265,000 tons of dioxin-contaminated waste until 1997. Dioxins are a family of chemicals produced as a ... and dioxins. Dioxin was used as a waste oil in Times Beach, Missouri. Days after the chemicals were introduced to the community ... one of the largest contributors releasing harmful dioxins left in the United States is waste incineration. Dioxins have been ...
"Dioxins". National Institute of Environmental Health Sciences. Retrieved 2020-03-09.. *^ a b c Odabasi, Mustafa; Elbir, Tolga; ... the transformation of TCS during manufacturing leads to the production of dioxins into aquatic habitats. Dioxins have been ...
Dioxins. Some cattle raised in the United States feed on pastures fertilized with sewage sludge. Elevated dioxins may be ...
Dioxin • Polycyclic aromatic hydrocarbons • Radioactive contamination • Volatile organic compounds Waste - Electronic waste • ...
When confronted by the CDC, Bliss stated that he did not know where the dioxin could have come from. Because dioxin was a by- ... Results revealed dioxin concentrations as high as 0.3 ppm along the town's entire network of roads. On December 23, 1982, the ... In the same document, however, the CDC reported that the half-life of dioxin was one year. Based on this estimate, which was ... Today, the half-life of dioxin is estimated to be seven to eleven years. The EPA did not become heavily involved with the ...
PCP contains dioxins as contamination. Dioxins damage the human immune system. "foa.org" (PDF). Retrieved 2011-04-18. Guar in ... "Dioxins and their effects on human health". 2010-05-01. Retrieved 2012-02-08. Guar Gum Cultivation and Information Current guar ... In July 2007, the European Commission issued a health warning to its member states after high levels of dioxins were detected ...
In 2008, a dioxin poisoning event caused the 2008 Irish pork crisis in which Irish pork was recalled worldwide. Four Big ... Chawla, Raghav (2005). "Dioxin poisoning". Student BMJ. 13: 45-88. Seki, Yoshihiko; Kawanishi, Shosuke; Sano, Seiyo (1987). " ... Polychloronated Dibenzo-p-dioxins, and Polychlorinated Dibenzofurans as Endocrine Disrupters-What We Have Learned from Yusho ... "Long-Term Effects of Polychlorinated Biphenyls and Dioxins on Pregnancy Outcomes in Women Affected by the Yusho Incident". ...
"Dioxin Factsheet"; "Siyabona Theatre"; "The Word Becomes Cassette" by William Levy; "Tristam and Them" comic.(28pp) out of ...
NIEHS dioxin fact sheet "Dioxins and Dioxin-like Compounds in the Food Supply: Strategies to Decrease Exposure", a 2003 report ... The word "dioxins" may also refer to other similarly acting chlorinated compounds (see Dioxins and dioxin-like compounds). The ... Dioxins are present in cigarette smoke. Dioxin in cigarette smoke was noted as "understudied" by the US EPA in its "Re- ... Later, dioxins were found in Times Beach, Missouri and Love Canal, New York and Seveso, Italy. More recently, dioxins have been ...
TRI Dioxin and Dioxin-like Compounds Toxic Equivalency Reporting Rule - Proposed Rule (US EPA) Archived at webcitation on 2 ... With the TEFs, the toxicity of a mixture of dioxins and dioxin-like compounds can be expressed in a single number - the toxic ... Thus, TEF values for these compounds are in the process of review Dioxins and dioxin-like compounds Van den Berg M, Birnbaum LS ... Toxic equivalency factor (TEF) expresses the toxicity of dioxins, furans and PCBs in terms of the most toxic form of dioxin, 2, ...
During the production process carcinogenic byproducts, dioxins, are produced which are toxic to humans and animals. Dioxins ... US EPA, ORD (28 January 2014). "Learn about Dioxin". US EPA. Retrieved 17 December 2018. "Vegan Leather Isn't As Ethical As You ...
... were found to contain elevated levels of the cancer-causing chemical dioxin in November 2006. The dioxin was located in ... Barringer, Felicity (July 4, 2007). "E.P.A. and Dow in Talks on Dioxin Cleanup at Main Factory". The New York Times. Retrieved ... Agent Orange, a chemical defoliant containing dioxin, was also manufactured by Dow in New Plymouth, New Zealand, and Midland, ... Barringer, Felicity (July 18, 2007). "Michigan: Dioxin Deal". The New York Times. Retrieved 2008-04-17. "Superfund Alternative ...
The study tracked the origin of the dioxins using computer models from the sources that produced it and found that the dioxin ... Dioxins are very toxic and according to the World Health Organization, they can cause "reproductive and developmental problems ... "Dioxins and their effects on human health". World Health Organization. October 2016. Retrieved March 10, 2018. Lucas, Anne E. ... Barry Commoner, found that Inuit women in the Arctic in Nunavut, Canada were found to have high levels of dioxin in their ...
Retrieved from "https://en.wiktionary.org/w/index.php?title=dioxins&oldid=55337798" ...
Table of laboratory methods panels for Dioxins. Chemical. Specimen Type. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD). CAS No. ... Biomonitoring Factsheet: Dioxins, Furans and Dioxin-Like Polychlorinated Biphenyls. National Report on Human Exposure to ... Predictors of serum dioxins and PCBs among peripubertal Russian boys. Burns JS, Williams PL, Sergeyev O, Korrick S, Lee MM, ... Serum dioxins and polychlorinated biphenyls are associated with growth among Russian boys. Burns JS, Williams PL, Sergeyev O, ...
... a collective term for a group of environmental contaminants that includes certain dioxin, furan, and dioxin-like PCB ( ... Dioxins, a collective term for a group of environmental contaminants that includes certain dioxin, furan, and dioxin-like PCB ( ... Dioxins and furans are released into the air from combustion processes. The wide use of PCBs as dielectric and coolant fluids ... Dioxin Analysis Results/Exposure Estimates June 2006; Updated November 2007 *Non-TDS Foods Analyzed for PCDD/PCDFs in 2001-2003 ...
"Dioxin Controversy - What are Dioxins?". uow.edu.au.. *^ a b Sharon Beder. The dioxin controversy: spilling over into schools ... Dioxin screening[edit]. There are two main methods for screening of dioxins and dioxin-like compounds: *CALUX, or Chemical ... Finally, dioxin may refer to 1,4-Dioxin, the basic chemical unit of the more complex dioxins. This simple compound is not ... Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo-p-dioxin. There are 75 PCDD ...
Dioxins are chemical compounds that are hazardous to health. They are no longer produced in the U.S. but they are everywhere ... Sometimes the term dioxin is also used to refer to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), one of the most toxic dioxins. ... absorbs dioxins through skin contact with air, soil, or water. Dioxins in tampons and water bottles. Concerns have been raised ... Dioxin testing for humans is not routinely available. One way to reduce the personal risk from dioxins is by choosing lean ...
Dioxins have been ... read more. About DIOXINS: According to the U.S. Environmental Protection Agency (EPA), dioxins a family ... Synonym(s): DIOXIN; 2,3,7,8-TCDD; DIOKSYNY (POLISH) ; DIOXIN; DIOXIN (HERBICIDE CONTAMINANT) ; DIOXINE; NCI-C03714; TCDBD; TCDD ... About DIOXINS: According to the U.S. Environmental Protection Agency (EPA), dioxins a family of toxic chemicals that share a ... Dioxins have been characterized by EPA as likely human carcinogens and are anticipated to increase the risk of cancer at ...
FSIS conducts periodic surveys to gather information on dioxins, furans, and dioxin-like PCBs in U.S. meat and poultry products ... Page includes links to dioxin resources and historical information. ... DIOXIN FY2013 Survey: Dioxins and Dioxin-Like Compounds in the U.S. Domestic Meat and Poultry Supply (May 2015; PDF Only) ... DIOXIN 08 SURVEY: Dioxins and Dioxin-Like Compounds In the U.S. Domestic Meat and Poultry Supply (Oct 2009; PDF Only) ...
One chemical in this group, 2,3,7,8-tetrachlorodibenzo-p-dioxin or 2,3,7,8-TCDD, has been shown to be very toxic in animal ... Exposure to chlorinated dibenzo-p-dioxins (CDDs) (75 chemicals) occurs mainly from eating food that contains the chemicals. ... One chemical in this group, 2,3,7,8-tetrachlorodibenzo-p-dioxin or 2,3,7,8-TCDD, has been shown to be very toxic in animal ... CDDs are a family of 75 chemically related compounds commonly known as chlorinated dioxins. One of these compounds is called 2, ...
Biomonitoring Factsheet: Dioxins, Furans and Dioxin-Like Polychlorinated Biphenyls. National Report on Human Exposure to ... Body burden levels of dioxin, furans, and PCBs among frequent consumers of Great Lakes sport fish. The Great Lakes Consortium. ... Table of laboratory methods panels for Dioxins, Furans, coplanar polychlorinated biphenyls (PCBs). Chemical. Specimen Type. ... 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (OCDD). CAS No. 3268-87-9. serum or plasma. ...
... is moving forward on setting a safety limit for exposure to dioxin, a ubiquitous, highly toxic and carcinogenic chemical that ... Dioxin Timeline. EPAS Dioxin Assessment: No Safety Standard After Nearly Three Decades of Work. Dioxin and related dioxin-like ... Dioxin Timeline. EPAS Dioxin Assessment: No Safety Standard After Nearly Three Decades of Work. Dioxin and related dioxin-like ... 2003-2009 - Dioxin pollution in people. EWGs body burden studies have found dioxin and other chlorinated dioxins and furans in ...
Dioxin Science Plan (Last updated May 2009). *Dioxin Toxicity Equivalency Factors (TEFs) for Human Health (Last updated Dec ... Dioxin at Superfund Sites. This page provides information on dioxin contamination as it relates to the cleanup Superfund sites ... Environmental Assessment Publications on Dioxin. * IRIS Assessment: Reanalysis of Key Issues Related to Dioxin Toxicity and ... Cleanup Levels for Dioxin at Superfund Sites. This page summarizes information about risk assessment at Superfund sites with ...
Learn about Dioxin. Dioxin Key Facts. *Dioxins are called persistent organic pollutants (POPs), meaning they take a long time ... Most Toxic Dioxin. The most studied and most toxic of all dioxins is 2,3,7,8-tetrachlorodibenzo-p-dioxin. In 2012, EPA released ... FDAs Chemical Contaminants: Dioxin. *Questions and answers about dioxin and food safety - Dioxin Related Activities (Feb 2012) ... Where does dioxin come from?. Industrial activities: Dioxin is not produced or used commercially in the United States. It is a ...
Executive Summary of the Assessment of the health risk of dioxins ... Dioxins Links. *Factual links. Some of the websites providing factual information on Dioxins: *1.1 Some Q&As and FAQs on ... www.niehs.nih.gov/health/topics/agents/dioxins/ * Health Canada provides information on its environment site about dioxins and ... 2.2 Some of the sites advocating that dioxins present more risk. *2.3 Some of the sites advocating that dioxins present less ...
Toxicological profile for Chlorinated Dibenzo-p-dioxins (CDDs). Atlanta, GA: U.S. Department of Health and Human Services, ...
Dioxins are a group of toxic chemical compounds that are a by-product of industrial processes. They are pervasive in the ... Dioxin-related food safety disasters have regularly cropped up in the media over the past decade. Perhaps the most devastating ... Now that the EU has set the global standards for dioxin levels in food, should the U.S. government follow suit? While doing so ... On July 1, the European Union acted to mitigate these risks by imposing tough limits on the levels of dioxins in food and feed ...
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ... The analysis of dioxins is particularly demanding due to low level regulatory exposure limits and complex sample matrices ... New Methods for Pesticides, Dioxins, Microcystins, PCBs , PFASs, and PPCPs Pesticide Screening Application Solution with UNIFI ... Dioxins are persistent organic pollutants (POPs) formed during combustion processes and found throughout the environment. ...
Recommendation on monitoring of dioxins, dioxin-like PCBs and non-dioxin-like PCBs in foodstuffs - EUR-Lex ... Monitoring of dioxins and PCBs in food and feed. EU-wide data on the presence of dioxins and PCBs in the food chain are ... Dioxins and some PCBs referred to as dioxin-like PCBs (due to their similar toxicological properties) are often considered ... In 2001, the European Commission set for the first time maximum levels for dioxins, which were extended to dioxin-like PCBs in ...
The FDA recommends that tampons be free of dioxin and other chemicals, but tests show small but detectable levels of these ... The FDA recommends that tampons be free of dioxin and other chemicals, but tests show small but detectable levels of these ... Dioxins, Pesticides, and Fragrance Chemicals Detected in Tampons. The FDA recommends that tampons be free of dioxin, including ... "State-of-the art testing of tampons and tampon materials that can detect even trace amounts of dioxin has shown that dioxin ...
SGS dioxin and furan analysis can accurately measure trace quantities to improve your site safety. Find out more. ... Toxic dioxins and furans can accumulate through industrial processes. ... Environment Dioxins and Furans. Dioxins and furans are carcinogenic and so are some of the most regulated environmental ... Home › Environment › Air, Noise, Odor and Vibration › Laboratory Analysis › Specialty Analyses › Dioxins and Furans ...
Dioxin may refer to: 1,2-Dioxin or 1,4-Dioxin, two unsaturated heterocyclic 6-membered rings where two carbon atoms have been ... "dioxin" 1,4-Dioxane, the saturated analog Agent orange, of which TCDD is a marginal component Digoxin Dioxin affair, a 1999 ... in which two benzene rings are connected through two oxygen atoms Dioxins and dioxin-like compounds, a diverse range of ... the parent compound also known as dibenzodioxin or dibenzo-p-dioxin (molecular formula C12H8O2), ...
Dioxin may refer to 1,4-dioxin or p-dioxin, the basic chemical unit of the more complex dioxins. This simple compound is not ... "Dioxin Controversy - What are Dioxins?". uow.edu.au. Sharon Beder. The dioxin controversy: spilling over into schools, ... They include: Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo-p-dioxin. There ... Polychlorinated dibenzo-p-dioxins Polychlorinated dibenzofurans Polychlorinated biphenyls 1,4-dioxin Dioxins have different ...
Dow says theres no danger and the state has proposed easing dioxin cleanup standards. Meanwhile, the Environmental Protection ... it will say that dioxin is more dangerous than current regulations assume. Living On Earths science editor Diane Toomey ... Agency is expected to soon release its long-awaited report on dioxins health hazards, and by most accounts, ... environmentalists in Michigan have been pressuring the state to clean up what they say are dangerous levels of dioxin in the ...
Thursday, the state had announced that low levels of a highly toxic form of dioxin had been found in the ground water in one of ... The levels of dioxin are thousands of times lower than those found in Times Beach, Mo., and there is as yet no evidence that ... The level of dioxin found is so little, its like a shot glass of vermouth in 50,000 boxcars of gin, he said. Weve got ... The discovery of dioxin has jolted the residents of this community of 27,000. The Laurel Park landfill receives wastes from ...
Gene-Dioxin Interactions and Pubertal Onset in Boys: Findings from the Russian Childrens Study. Julia R. Barrett ... Dioxin Exposure and Cardiovascular Disease: An Analysis of Association. Valerie J. Brown ...
Mississippi jury has rejected a couples claim that dioxins from the DuPont Co.s plant on the Mississippi Gulf Coast were ... A Jones County, Mississippi jury has rejected a couples claim that dioxins from the DuPont Co.s plant on the Mississippi Gulf ... The Jones County jury found that DuPont "negligently released dioxins and arsenic from the DeLisle facility" but did not link ... Louis oysterman Glen Strong $14 million in damages after concluding dioxins from the DeLisle plant did cause his rare blood ...
Vietnam Study Finds Dioxin in Food Chain. Asia: Agent Orange defoliant used by U.S. in war has created environmental and health ... "Dioxin contamination related to Agent Orange was found in grass carp growing in fish ponds excavated out of the terrain in the ... Using research that ranged from satellite imagery to soil sampling, the firm found high levels of dioxin, an Agent Orange ... Dioxin is also found in high levels in fish and animal tissue. ...
The study, on the current dioxin exposure and health data in the EU, was co-funded by the European Commissions Environment ... The results of an EU-funded study on dioxin exposure and health are now available from an on-line report. ... Dioxin exposure and health. The results of an EU-funded study on dioxin exposure and health are now available from an on-line ... The report concludes that the daily intake of dioxins and dioxin-like compounds is still above recommended levels for some ...
What doesnt often make the news is the fact that dioxin pollution is far more widespread than political poisonings. ... The deadly chemical dioxin has hit the headlines with the poisoning of Ukrainian opposition leader Viktor Yuschenko. ... One of the biggest sources of dioxin is the commonly used plastic PVC (vinyl). Dioxins are created during the production, use ... Once created dioxins persist in the environment for many years.. What products in my home are made of PVC? From shower curtains ...
... *2.1 What are the principal source of exposure to dioxins?*2.1.1 How do dioxins enter ... 2.1 What are the principal source of exposure to dioxins?. **2.1.1 How do dioxins enter the human body? ... 2. How are humans exposed to dioxins?*2.1 What are the principal source of exposure to dioxins? ... dioxin) receptor in mediating the biological effects of dioxin. These data have been collected in many experimental models in ...
  • FDA has been monitoring specific foods with the goal of identifying ways to reduce dietary exposure to dioxin. (fda.gov)
  • The endocrine disrupting activity of dioxins is thought to occur as a down-stream function of AH receptor activation, with thyroid status in particular being a sensitive marker of exposure. (wikipedia.org)
  • Over 90 percent of human exposure to dioxins comes through food, mainly animal products, such as dairy, meat, fish, and shellfish. (medicalnewstoday.com)
  • Dioxins have been characterized by EPA as likely human carcinogens and are anticipated to increase the risk of cancer at background levels of exposure. (ewg.org)
  • Exposure to chlorinated dibenzo-p-dioxins (CDDs) (75 chemicals) occurs mainly from eating food that contains the chemicals. (cdc.gov)
  • After nearly 30 years of delays caused by pressure from chemicals and defense industries, the US Environmental Protection Agency (EPA) is moving forward on setting a safety limit for exposure to dioxin, a ubiquitous, highly toxic and carcinogenic chemical that people of all ages ingest daily with their food - starting at a mother's breast. (ewg.org)
  • The Environmental Working Group applauds the EPA for taking significant steps to set a long-overdue exposure limit for dioxin, a byproduct of combustion and various industrial processes that is found everywhere in the environment and in people's bodies. (ewg.org)
  • EWG researchers say, however, that the allowable exposure levels may well need to be tightened in the future because of growing evidence that dioxin is even more dangerous than scientists had thought. (ewg.org)
  • More recently, scientists have recognized that continuous, low-dose exposure to dioxin-like compounds, which include the notorious PCB's, is also a health threat. (ewg.org)
  • The EPA, which began its efforts to set safety limits for dioxin exposure almost 30 years ago, is focusing on a particular form called tetrachlorodibenzo-p-dioxin, or TCDD, the most toxic and best studied of this family of chemicals. (ewg.org)
  • EPA and its government partners are looking for ways to further reduce dioxins entering the environment and to reduce human exposure to them. (epa.gov)
  • The Environmental Protection Agency estimates that more than 95% of human dioxin exposure comes from dietary intake of animal fat. (ift.org)
  • According to the National Institute of Environmental Health Sciences, dioxin exposure can lead to increased cancer rates, reproductive and developmental problems, increased heart disease, and increased diabetes in humans. (ift.org)
  • In June 2002, EPA reported that two-thirds of Americans face an increased cancer risk as a result of exposure to toxic chemicals like dioxins. (ift.org)
  • EFSA staff ensures the continuity of data collection on dioxins and PCBs, integrating newly generated occurrence and exposure data into existing databases. (europa.eu)
  • With regard to dioxins and PCBs in feed, the CONTAM Panel also considers the level of carry over from feed to foods of animal origin and identifies feed materials which could be considered as sources of exposure. (europa.eu)
  • Studies show that dioxin collects in your fatty tissues, and according to a draft report by the US Environmental Protection Agency (EPA), dioxin is a serious public health threat that has no "safe" level of exposure! (mercola.com)
  • The results of an EU-funded study on dioxin exposure and health are now available from an on-line report. (europa.eu)
  • The study, on the current dioxin exposure and health data in the EU, was co-funded by the European Commission's Environment Directorate-General and has now been presented. (europa.eu)
  • The study, on the current dioxin exposure and health data in the EU, was co-funded by the European Commission's Environment Directorate-General and has now been presented to the Commission task force on dioxins. (europa.eu)
  • 2.1 What are the principal source of exposure to dioxins? (greenfacts.org)
  • Concerns over errors in a report on dioxin exposure in the New Plymouth suburb of Paritutu will be looked at by an expert reviewing the study, says the Minister of Health. (nzherald.co.nz)
  • Dioxin was in the defoliant sprayed over the jungles of Vietnam during the fighting there and thousands of veterans worry about the effects of possible exposure. (chicagotribune.com)
  • Food Standards Australia New Zealand (FSANZ) has conducted an analytical survey of dioxins in a range of food sampled in Australia with the purpose of assessing the level of risk to human health associated with the dietary exposure of the Australian population to dioxins. (foodstandards.gov.au)
  • The overall conclusion of this report is that, on the basis of the available data, taking into account all the inherent uncertainties and limitations, the public health and safety risk for all Australians from exposure to dioxins from foods is very low. (foodstandards.gov.au)
  • Long term high levels of exposure to dioxins have the potential to cause a range of toxic effects in animals and humans, including skin lesions, reproductive disorders and cancer. (foodstandards.gov.au)
  • The consumption of animal products with high fat content, such as meat and dairy products, can increase human exposure to dioxins. (foodstandards.gov.au)
  • For all age groups as well as for the lifetime exposure, the mean and 95th percentile monthly dietary exposures were below the Australian tolerable monthly intake for dioxins of 70 pg TEQ/kg body weight (bw)/month. (foodstandards.gov.au)
  • For the population group aged two years and above, representing a lifetime of exposure, mean estimated exposure to dioxins was 3.7-15.6 pg TEQ/kg bw/month (lower to upper bound). (foodstandards.gov.au)
  • Toddlers aged 2-4 years were estimated to have the highest exposure to dioxins (mean 6.2-36.7 and 95th percentile 12.1-66.2 pg TEQ/kg bw/month, lower to upper bound respectively) due to their higher food consumption relative to body weight. (foodstandards.gov.au)
  • The mean estimated dietary exposure to dioxins calculated for infants aged 9 months was 11.8-60.8 pg TEQ/kg bw/month (lower to upper bound). (foodstandards.gov.au)
  • In addition, concern has arisen in the small town of Kirkjubaejarklaustur, in South Iceland, where dioxin levels were recorded at 95 times the maximum exposure level in 2007. (globalissues.org)
  • And in Vestmannaeyjar, an island just off South Iceland, the dioxin level was 84 times the maximum exposure standard. (globalissues.org)
  • This study also provides evidence that the effect is dose-dependent (the higher the dioxin exposure, the bigger the effect) and male-mediated (the effect was observed in men with high dioxin exposure, not in women with high dioxin exposure). (reuters.com)
  • The Danish Environmental Protection Agency has requested an evaluation of health hazards by exposure to polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. (mst.dk)
  • Sources of human exposure to dioxins include food intake, drinking water, air inhalation and skin contact. (gov.hk)
  • Dietary intake is by far the most important and accounts for over 90% of dioxins exposure. (gov.hk)
  • Accidental exposure to large amount of dioxins could lead to the development of chloracne, a skin condition, excessive body hair and other skin lesions such as skin rashes and skin discolouration. (gov.hk)
  • Long-term exposure to dioxins is linked to impairment of the immune system, reproductive function, endocrine system and the developing nervous system. (gov.hk)
  • To accurately determine the risk of the population due to exposure to dioxins, an exposure assessment needs to be performed. (gov.hk)
  • In evaluating dietary exposure to dioxins, one needs to examine the dioxin levels in different food items and the food consumption amount in the population. (gov.hk)
  • Prevention of excessive exposure to dioxins should start with environmental control. (gov.hk)
  • As dioxins are mainly present in the fatty part of food, consuming low-fat products, trimming fat from meat and meat products, reducing the amount of animal fat used in food preparation and using cooking methods that reduce fat (e.g. broiling, baking) are useful measures to minimise dietary dioxin exposure. (gov.hk)
  • After more than 20 years of "assessment" the Environmental Protection Agency is finally expected later this month to release limits for safe exposure to dioxins, nasty industrial pollutants that cause cancer, among other health harms . (huffingtonpost.com)
  • Although dioxins are environmental contaminants, most dioxin exposure occurs through the diet, with over 95% coming through dietary intake of animal fats. (huffingtonpost.com)
  • Dioxin is considered a probable carcinogen at high enough levels, but the FDA said the danger was in cumulative lifetime exposure, not in eating a few chickens raised on the feed. (essential.org)
  • Sources of human exposure to dioxins include food intake, drinking water, air inhalation and skin contact, of which dietary intake is the most important source. (gov.hk)
  • As dioxins are mainly found in fat, the risk of dioxin exposure can be reduced by avoiding foods with a relatively high level of fat. (gov.hk)
  • The Department has also advised adults and children to avoid the risk of exposure to dioxin through skin by not camping, fishing, or picnicking near the San Jacinto River where the toxic waste ponds are located. (chron.com)
  • Infant Exposure to Dioxin-Like Compounds in Breast Milk. (questia.com)
  • Since these are the primary dietary sources of dioxins and since diet is the primary non-occupational exposure route, this is a critical issue for the farm family. (cornell.edu)
  • Cognitive functioning in preschool children is negatively impacted by in utero exposure to PCBs and dioxins (Patandin, et al, 1999). (cornell.edu)
  • Birth weight and postnatal growth until 3 months of age were impacted by in utero exposure to PCBs and dioxins (Patandin, et al, 1998). (cornell.edu)
  • For most New Zealanders, about 90 percent of dioxin exposure is through food. (healthed.govt.nz)
  • Small amounts of exposure can also occur from breathing in dioxin, skin absorption, and inadvertently eating or drinking contaminated soil or dust. (healthed.govt.nz)
  • This means that cancer development following dioxin exposure may depend on other causes of cancer like tobacco use. (healthed.govt.nz)
  • The Institute of Medicine of the National Academy of Sciences in the United States of America regularly reviews the evidence about dioxin exposure and health. (healthed.govt.nz)
  • It makes a list of conditions that it accepts as being associated with dioxin exposure. (healthed.govt.nz)
  • There is some evidence that dioxin exposure is associated with cancers of the respiratory system, prostate cancer, multiple myeloma, early onset transient peripheral neuropathy, porphyria cutanea tarda, Type II diabetes, hypertension, AL amyloidosis, and spina bifida in offspring. (healthed.govt.nz)
  • Many of these diseases are also associated with things other than dioxin exposure. (healthed.govt.nz)
  • Is there a medical test for dioxin exposure? (healthed.govt.nz)
  • A person who had a high level of exposure in the past may have a serum dioxin test which shows low or minimal levels of dioxin now. (healthed.govt.nz)
  • Are there any treatments for dioxin exposure? (healthed.govt.nz)
  • How can I reduce my current exposure to dioxins? (healthed.govt.nz)
  • Dioxin exposure has been linked to learning disabilities, reproductive problems, endometriosis and diabetes. (cnn.com)
  • The developing fetus and newborns, exposed through breast milk, are considered particularly vulnerable to dioxin exposure. (cnn.com)
  • We are being poisoned in NZ by low level exposure to Dioxin! (foodsafetynews.com)
  • The contribution of environmental biomonitoring with lichens to assess human exposure to dioxins. (springer.com)
  • A December 2007 PubMed search of English-language epidemiologic studies and their citations regarding dioxin exposure and CVD mortality provided the basis for the systemic review. (innovations-report.com)
  • Although a number of epidemiologic studies have examined the association of dioxin exposure with CVD morbidity or mortality, the authors found no published systematic reviews on this topic. (innovations-report.com)
  • EHP editor-in-chief Hugh A. Tilson, PhD, said, "With cardiovascular disease a leading cause of death in many countries, the potential role of dioxin exposure as a preventable risk factor could be of substantial interest. (innovations-report.com)
  • The U.S. Environmental Protection Agency's Office of Research and Development has found a University of Michigan dioxin exposure study to be of limited value in fully evaluating human exposure to levels of dioxin in the Tittabawassee River and Saginaw River and Bay. (eponline.com)
  • The University of Michigan Dioxin Exposure Study (UMDES) was conducted in response to community concerns that dioxin compounds from the Midland-based Dow Chemical Co. had contaminated the city and surrounding areas. (eponline.com)
  • Understanding these issues is critical when evaluating associations between exposure and blood dioxin levels in sensitive populations, including children. (eponline.com)
  • The new report shows a general decrease in dietary exposure to dioxins and dioxin-like PCBs in Europe, comparing 2008-2010 with 2002-2004, of at least 16 % and up to 79 % for the general population, with a similar decrease for toddlers and other children. (mondaq.com)
  • Exposure to non-dioxin-like PCBs, a sub-set of PCBs with different toxicological properties, also decreased. (mondaq.com)
  • Dioxin exposure during pregnancy impairs the development of mammary glands during pregnancy and may cause women to not produce enough milk for their newborns, a new study finds. (ecochildsplay.com)
  • The study, from the University of Rochester Medical Center, found that dioxin causes mammary cells to stop their cycle of proliferation as early as six days into pregnancy, and the effects of exposure can last through mid-pregnancy. (ecochildsplay.com)
  • Human exposure to dioxins is usually through diet, as the chemical enters the food chain through emissions settling on farmland, and through livestock and fish. (ecochildsplay.com)
  • Researchers found that in tissue samples from mice, a 50% decrease in new epithelial cells was seen after dioxin exposure, and because mammary gland cells have a high rate of growth during early to mid-pregnancy, this is an important finding. (ecochildsplay.com)
  • The group is also investigating a possible link between breast cancer and dioxin exposure. (ecochildsplay.com)
  • It's about personal ways to reduce your exposure to dioxin and similar problems. (lbbs.org)
  • According to the EPA report, not only does there appear to be no 'safe' level of exposure to dioxin, but levels of dioxin and dioxin-like chemicals have been found in the general US population that are 'at or near levels associated with adverse health effects. (lbbs.org)
  • What health effects are related to exposure to dioxin and dioxin-like compounds? (lbbs.org)
  • In the Netherlands, the pre- and postnatal exposure to dioxins have been studied prospectively since 1987. (uva.nl)
  • We observed no trend of increasing risk for any cause of death with increasing dioxin exposure. (biomedsearch.com)
  • According to the World Health Organization, dioxins are highly toxic and in addition to cancer, exposure to dioxins can damage the immune system, interfere with hormones, and lead to reproductive problems. (organicauthority.com)
  • People living near incinerators receive the highest doses of dioxin, which persists in fatty tissue for many years, but up to 90 percent of human dioxin exposure comes from food, particularly meat, fish, and dairy products. (social-ecology.org)
  • In some cases of short-term and long-term exposure to Dioxin, humans have been known to display signs of extreme chloracne, which is an acne-like condition that develops within months of the first intake of Dioxin. (creationwiki.org)
  • According to this analysis, dioxin exposure in children 1 to 5 years old exceeds EPA's reference dose and that children 6 to 11 years old have dioxin exposure that is virtually identical to the reference dose. (chej.org)
  • We know that over 95% of our daily exposure results from ingestion o f animal fat, primarily meat and dairy and that people who live near specific dioxin sources are exposed to even higher concentrations. (chej.org)
  • While the scientists limited the pregnant rats to small amounts of dioxin exposure, these levels are still high compared to most people's exposure from the environment. (beforeitsnews.com)
  • They chose to work on juvenile fish because few studies for dioxin exposure exist on this critical life-stage. (wisc.edu)
  • Carvan said their technique "more closely mimics actual environmental exposure to dioxin. (wisc.edu)
  • And as for the trouts' noses, testing whether their sense of smell was actually impaired by dioxin exposure was not part of Carvan's research, but he'd like to follow up to see if it leads to behavioral problems and perhaps impeded spawning success. (wisc.edu)
  • They are mostly by-products of various industrial processes - or, in case of dioxin-like PCBs and PBBs , part of intentionally produced mixtures. (wikipedia.org)
  • Under certain conditions PCBs may form dibenzofurans/dioxins through partial oxidation. (wikipedia.org)
  • Toxic equivalence factors (TEFs) exist for seven congeners of dioxins, ten furans and twelve PCBs. (wikipedia.org)
  • Incidents of contamination with PCBs are also often reported as dioxin contamination incidents since it is this toxic characteristic which is of most public and regulatory concern. (wikipedia.org)
  • It is important to note that TCDD, along with the other PCDDs, PCDFs and dioxin-like coplanar PCBs are not direct agonists or antagonists of hormones, and are not active in assays which directly screen for these activities such as ER-CALUX and AR-CALUX . (wikipedia.org)
  • A mixture of PCBs such as Aroclor may contain PCB compounds which are known estrogen agonists , but on the other hand are not classified as dioxin-like in terms of toxicity. (wikipedia.org)
  • Body burden levels of dioxin, furans, and PCBs among frequent consumers of Great Lakes sport fish. (cdc.gov)
  • The dioxin-like PCBs have both biphenyl rings in the same plane (flat appearance), which allows them to act like dioxins in the body. (epa.gov)
  • Dioxins and polychlorinated biphenyls (PCBs) are toxic chemicals that persist in the environment and accumulate in the food chain. (europa.eu)
  • In contrast to dioxins, PCBs had widespread use in numerous industrial applications, and were produced in large quantities for several decades with an estimated total world production of 1.2-1.5 million tonnes, until they were banned in most countries by the 1980s. (europa.eu)
  • Dioxins and PCBs are found at low levels in many foods. (europa.eu)
  • Dioxins and some PCBs referred to as dioxin-like PCBs (due to their similar toxicological properties) are often considered together within the context of public health. (europa.eu)
  • Other PCBs referred to as 'non dioxin-like PCBs' have a different mechanism of toxicity but can also cause adverse effects on health. (europa.eu)
  • EFSA collects and analyses occurrence data on dioxins and PCBs in food and feed. (europa.eu)
  • It produces bi-annual monitoring reports on the levels of dioxins and PCBs in food and feed. (europa.eu)
  • EFSA's Panel on Contaminants in the Food Chain (CONTAM) provides risk managers with scientific advice to inform their decision-making on the setting of maximum levels of dioxins and PCBs in food and feed. (europa.eu)
  • EFSA provides scientific advice and risk assessments on dioxins and PCBs for EU risk managers to help them assess the need for regulatory measures as regards the safety of contaminated food and feed. (europa.eu)
  • Make recommendations for the collection of further data on dioxins and PCBs that enable the refinement of risk assessments. (europa.eu)
  • EU-wide data on the presence of dioxins and PCBs in the food chain are collected and analysed in bi-annual reports. (europa.eu)
  • In 2001, the European Union adopted a strategy on dioxins and PCBs aimed at reducing contamination levels of these substances in the environment, in feed and in foodstuffs in order to ensure a high level of public health protection. (europa.eu)
  • In 2001, the European Commission set for the first time maximum levels for dioxins, which were extended to dioxin-like PCBs in 2006. (europa.eu)
  • Regulation EU 1259/2011 and Regulation EU 277/2012 recently updated them and set maximum levels for non dioxin-like PCBs in food and feed respectively. (europa.eu)
  • These regulations took account of recent data on the presence of dioxins and PCBs in food and feed published in two EFSA scientific monitoring reports in 2010, as well as an EFSA scientific opinion on the presence of non dioxin-like PCBs in feed and food. (europa.eu)
  • Member States are responsible for the monitoring of the levels of dioxins and PCBs in food. (europa.eu)
  • In 2010, EFSA received the mandate from the European Commission to collect and analyse, on a continuous basis, all available data on dioxins and PCBs in food and feed. (europa.eu)
  • If the dioxin-like PCBs (non-ortho and mono-ortho PCBs) are also considered, the daily TEQ intake can be a factor of 2-3 higher. (greenfacts.org)
  • Incidents of contamination with PCBs are often reported as dioxin contamination incidents since these are of most public and regulatory concern. (wikipedia.org)
  • Dioxins and PCBs belong to the group of compounds known as Persistent Organic Pollutants (POPs). (sigmaaldrich.com)
  • When planning treatments against diabetes, the body burden of PCBs and dioxins should be carefully considered, especially for women. (diabetesjournals.org)
  • Polychlorinated biphenyls (PCBs) and dioxins are persistent organic pollutants (POPs) with long half-lives in the human body, and they may act as endocrine disruptors and exhibit endocrine system effects ( 1 ). (diabetesjournals.org)
  • Dioxins' includes the polychlorinated dibenzodioxins (PCDDs or dioxins), the closely related polychlorinated dibenzofurans (PCDFs or furans) and polychlorinated biphenyls (dioxin-like PCBs, or PCBs). (foodstandards.gov.au)
  • FSANZ conducted a survey of both PCDD/Fs and for dioxin-like PCBs in a range of foods representative of the total diet. (foodstandards.gov.au)
  • The food survey analysed composite food samples for each of the 29 PCDD/F and PCBs, for which the WHO developed toxicity equivalency factors (TEFs) to the most toxic dioxin congener TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin). (foodstandards.gov.au)
  • Dioxin-like compounds are polychlorinated biphenyls, commonly known as dioxin-like PCBs, which behave like dioxin, so are generally classified with it in terms of toxicity. (globalissues.org)
  • Dioxins and dioxin-like compounds, including PCDDs, PCDFs and PCBs, are persistent organic pollutants (POPs) that are resistant to environmental degradation. (genome.jp)
  • The terrible news is that PCBs and dioxins were found to be dangerously high in certain foods. (notmilk.com)
  • One shows even less compassion to his or her own body by ingesting concentrated portions of dioxins and PCBs. (notmilk.com)
  • Polychlorinated dibenzo- p -dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are toxic and persistent organic pollutants that are able to enter the food chain, accumulate in the fat tissues of animals, and consequently pose a serious risk for human health. (springer.com)
  • Toxic equivalency factors for dioxin-like PCBs. (springer.com)
  • The European Food Safety Authority has published a new report on levels of dioxins and polychlorinated biphenyls (PCBs) in food and feed. (mondaq.com)
  • Dioxins and PCBs are persistent environmental pollutants which can accumulate in the food chain. (mondaq.com)
  • The toxicity of other dioxins and chemicals like PCBs that act like dioxin are measured in relation to TCDD. (lbbs.org)
  • Dioxins and PCBs are environmental pollutants, proven to be immunotoxic. (uva.nl)
  • Venapuncture was performed to assess hematological (Hemoglobin, thrombocytes, thrombopoietin) and immunological (leukocytes, leukocyte differentiation) parameters and the current serum levels of dioxin, dioxinlike(dl)-PCBs and PBDEs. (uva.nl)
  • Dioxins and furans are released into the air from combustion processes. (fda.gov)
  • Most tampons are made from cotton, rayon, or another pulp fiber, but these materials may contain toxic disinfection byproducts from the chlorine bleaching process, including dioxins and furans, as well as pesticides from non-organic cotton. (mercola.com)
  • Dioxins and furans are carcinogenic and so are some of the most regulated environmental contaminants. (sgs.com)
  • Produced inadvertently by industrial processes such as waste incineration, chemical manufacturing and paper bleaching, dioxins and furans can be found in the air, in water and contaminated soil. (sgs.com)
  • High-resolution mass spectrometry is the only legally accepted analytical technique for quantifying dioxins and furans. (sgs.com)
  • The AMESA-D utilizes the water cooled probe method with Isokinetic sampling system coupled with XAD-II adsorbent cartridge for Long-term sampling of dioxins (PCDD), furans (PCDF) and other persistent organic contaminant (POPs). (environmental-expert.com)
  • This book provides a tool for today's environmental researchers by focusing on an integrated approach to managing environmental pollution problems due to dioxins and furans. (routledge.com)
  • The overall objective of this book is not simply to provide a general reference, but to serve as a resource for developing approaches to managing environmental pollution problems due to dioxins and furans. (routledge.com)
  • Source and Formation of Dioxins and Furans. (routledge.com)
  • Global Contamination and Movement of Dioxins and Furans in Environment. (routledge.com)
  • Health Effects of Dioxins and Furans. (routledge.com)
  • Analytical Method for Dioxins and Furans. (routledge.com)
  • San Francisco Bay was placed on the State of California's 303(d) list of impaired waters in 1998 as a result of elevated concentrations of dioxins and furans (commonly referred to as 'dioxin') in fish. (sfei.org)
  • Understanding the performance of different lichen species as biomonitors of atmospheric dioxins and furans: potential for intercalibration. (springer.com)
  • Dioxins and furans were byproducts formed during the manufacture of chlorine-based products, including chlorophenolic compounds manufactured at the plant since the 1930s. (mlive.com)
  • Dow Chemical acknowledges that, for decades, its plant in Midland polluted the watershed with dioxins and furans - chemical byproducts that may cause cancer and damage reproductive and immune systems. (manufacturing.net)
  • Please explore our range of standards for dioxins and furans below and get in touch if you have questions about how we can support you in your analytical testing. (lgcstandards.com)
  • Dioxins and dioxin-like compounds ( DLCs ) are compounds that are highly toxic environmental persistent organic pollutants (POPs). (wikipedia.org)
  • Because dioxins refer to such a broad class of compounds that vary widely in toxicity, the concept of toxic equivalency factor (TEF) has been developed to facilitate risk assessment and regulatory control. (wikipedia.org)
  • In reference to their importance as environmental toxicants the term dioxins is used almost exclusively to refer to the sum of compounds (as TEQ) from the above groups which demonstrate the same specific toxic mode of action associated with TCDD . (wikipedia.org)
  • Dioxins are a group of highly toxic chemical compounds that are harmful to health. (medicalnewstoday.com)
  • CDDs are a family of 75 chemically related compounds commonly known as chlorinated dioxins. (cdc.gov)
  • Dioxins refers to a group of toxic chemical compounds that share certain chemical structures and biological characteristics (see figure 1). (epa.gov)
  • Although environmental levels of dioxins have decreased in the last 30 years, dioxins are extremely persistent compounds and break down very slowly. (epa.gov)
  • The National Center for Environmental Assessment of the US EPA provides a site on Dioxin and Related Compounds, including assessments and regulations. (greenfacts.org)
  • Dioxins are a group of toxic chemical compounds that are a by-product of industrial processes. (ift.org)
  • In the context of EFSA's work, 'dioxins' refers to two groups of compounds: Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). (europa.eu)
  • And my concern was that this technique has not yet been validated for dioxin-like compounds. (loe.org)
  • The report concludes that the daily intake of dioxins and dioxin-like compounds is still above recommended levels for some parts of the population. (europa.eu)
  • Recent studies from countries which started to implement measures to reduce dioxin emissions in the late 80s, such as The Netherlands, United Kingdom and Germany, clearly show decreasing PCDD/PCDF and PCB levels in food and consequently a significantly lower dietary intake of these compounds by almost a factor of 2 within the past 7 years. (greenfacts.org)
  • Dioxins and dioxin-like compounds (DLCs) are a group of chemical compounds that are persistent environmental pollutants (POPs). (wikipedia.org)
  • These compounds are metabolized rapidly, but continuous intake from food may cause similar receptor activation as the background levels of dioxins. (wikipedia.org)
  • Dioxins' refers to a group of persistent chlorinated chemical compounds that have similar chemical structures and properties, and have similar biological characteristics, including toxicity. (foodstandards.gov.au)
  • Several hundred of these compounds exist, however, as evaluated by the World Health Organisation (WHO) in 1998, 29 of the compounds (congeners) were considered to have similar 'dioxin-like' toxicity. (foodstandards.gov.au)
  • Dioxin, and dioxin-like compounds, were found to be present in amounts higher than the recommended maximum levels, threatening the future of local farmers, and angering residents. (globalissues.org)
  • Dioxins are highly toxic compounds produced as a byproduct in some manufacturing processes, notably herbicide production and paper bleaching. (globalissues.org)
  • The findings revealed increased levels of dioxin and dioxin-like compounds in the majority of the samples. (globalissues.org)
  • Dioxins are a group of polychlorinated aromatic compounds arising either naturally or as by-products of industrial activities e.g. metal smelting, molding or burning of chlorine-containing organic chemicals such as plastics. (gov.hk)
  • Different dioxin compounds have different degree of toxicity. (gov.hk)
  • Of all types of dioxin-related compounds that have been identified, the most toxic one is 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD). (gov.hk)
  • The World Health Organization (WHO) has set a tolerable daily intake (TDI) for dioxins and dioxin-like compounds at a range of 1 - 4 pg TEQ per kilogram of body weight (bw) per day in 1998. (gov.hk)
  • Following a further evaluation carried out in 2001, the Joint Food and Agriculture Organization / World Health Organization Expert Committee on Food Additives (JECFA) concluded that, in view of their long half-lives, tolerable intakes for dioxins and dioxin-like compounds should be expressed as a monthly value and allocated a Provisional Tolerable Monthly Intake (PTMI) of 70 pg WHO-TEQ/ kg bw per month. (gov.hk)
  • Medindia provides you with the latest news and research breakthroughs on Dioxins and Related Compounds. (medindia.net)
  • Dioxins are a group of polychlorinated aromatic compounds arising either naturally or as by-products of industrial activities, e.g. metal smelting, moulding or burning of chlorine-containing organic chemicals such as plastics. (gov.hk)
  • Dioxins are a family of highly toxic chemical compounds. (cnn.com)
  • Dioxins, environmental pollutants resulting from the production and combustion of chlorinated compounds, have been linked to an increase in ischemic heart disease (IHD) and cardiovascular disease (CVD) mortality rates, as reported in a review article in the November 2008 issue of the peer-reviewed journal Environmental Health Perspectives (EHP). (innovations-report.com)
  • Dioxin is formed by burning chlorine-based chemical compounds with hydrocarbons. (lbbs.org)
  • Residues in wood duck eggs, based on toxicity equivalency factors (TEFs) for combined compounds, ranged from 0.2 to 611 parts per trillion (ppt) wet mass (70% were the toxic isomer 2,3,7,8-tetrachlorodibenzo-p-dioxin (tetraCDD)) and were 50 times higher in eggs from near the point source than from an uncontaminated reference site 111 km away. (usgs.gov)
  • First discovered as a byproduct of the manufacture of herbicides such as 2,4-D and Agent Orange, dioxins (actually a group of 75 similar compounds) are formed whenever certain common organic chemicals come into contact with chlorine at high temperatures. (social-ecology.org)
  • Dioxins are organic compounds that are not produced intentionally but only as a product of other chemical procedures such as incineration, wood and fuel burning, combustion, and others. (creationwiki.org)
  • This page provides information on dioxin contamination as it relates to the cleanup Superfund sites. (epa.gov)
  • This page summarizes information about risk assessment at Superfund sites with dioxin contamination. (epa.gov)
  • A summary of information about cleanup work at Superfund sites with dioxin contamination. (epa.gov)
  • But as the public learns more about dioxin contamination in Midland, a debate is heating up. (loe.org)
  • Dioxin contamination related to Agent Orange was found in grass carp growing in fish ponds excavated out of the terrain in the vicinity of the former Aluoi Valley air base," Hatfield noted. (latimes.com)
  • 2.2 What are the other possible sources of dioxin contamination? (greenfacts.org)
  • We do this by analysing the unique chemical fingerprint of the dioxins, as this pattern is often an indication of the source of the contamination. (wur.nl)
  • Large swaths of its soil was removed and re-sodded due to dioxin contamination. (environmentreport.org)
  • Signs along the trail warn walkers about dioxin contamination in some of the park's soil. (environmentreport.org)
  • We found virtually no relationship between soil contamination and blood dioxin levels. (environmentreport.org)
  • SAGINAW, MICHIGAN - A find of dioxin at the bottom of the Saginaw River could be the highest level of such contamination ever discovered in the nation's rivers and lakes, according to a federal scientist involved in cleanup efforts downstream from a Dow Chemical Co. plant in Midland. (chicagotribune.com)
  • MIDLAND, MI -- The U.S. Environmental Protection Agency is seeking public comment before the next phase of The Dow Chemical Co.'s dioxin contamination cleanup begins. (mlive.com)
  • Dioxin contamination cleanup efforts started in 2012. (mlive.com)
  • Federal government says it's failed to reach a deal with Dow Chemical Co. for the study and interim cleanup of dioxin contamination in the Tittabawassee River system. (manufacturing.net)
  • Since then, high levels of dioxin have also been detected in both the Westman Islands and in Kirkjubæjarklaustur, and contamination of meat sold both here and abroad is likely. (grapevine.is)
  • Last week, an analysis uncovered dioxin contamination in pork meat. (organicauthority.com)
  • Last week, Harles and Jentzsch filed for bankruptcy, after the source of the contamination was found to be industrial oil containing dioxin that was mixed with oil intended for animal feed. (organicauthority.com)
  • A wetland in central Arkansas was contaminated with polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans and because the area was a major waterfowl habitat, we studied the effects of the contamination on nesting wood ducks (Aix sponsa) during 1988-90. (usgs.gov)
  • Wood ducks were sensitive to dioxin and furan contamination, and we recommend it as an indicator species for monitoring biological impacts from these contaminants. (usgs.gov)
  • In February 2012, EPA established a chronic oral reference dose (RfD) for noncancer effects for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is used as a reference dioxin. (usda.gov)
  • In essence, multiplying the amount of a particular congener with its TEF produces the amount toxicologically equivalent to TCDD, and after this conversion all dioxin-like congeners can be summed up, and the resulting toxicity equivalent quantity (TEQ) gives an approximation of toxicity of the mixture measured as TCDD. (wikipedia.org)
  • Chinese hamster ovary cells were transiently transfected with an AhR-responsive reporter gene, wild-type mouse AhR, or CA-AhR, treated with 10 nM 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) or vehicle alone (1% DMSO), and analyzed as described ( 9 ). (pnas.org)
  • The study found a mean level of 7.5 parts per trillion of 2,3,7,8 TCDD, the most toxic form of dioxin, in samples of breast milk from the 50 women. (nytimes.com)
  • The chemical blend included several types of tetrachlorodibenzo-p-dioxin (TCDD) that are linked to a range of health issues including decreased odds of male offspring. (reuters.com)
  • TCDD is the most toxic type of dioxin, according to the World Health Organization. (reuters.com)
  • We have used a high density microarray hybridization approach to characterize the transcriptional response of human hepatoma HepG2 cells to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). (nih.gov)
  • 2,3,7,8-Tetrachlorodibenzo-p -dioxin (TCDD), a widespread environmental contaminant and known endocrine disruptor, has been associated with alterations in ovarian function and steroid levels in animal studies. (lww.com)
  • Dioxins (most notably 2,3,7,8-tetrachlorodibenzo- p -dioxin, TCDD, Figure 6.1) and related halogenated aromatic hydrocarbons (e.g. poly-chlorinated biphenyls and dibenzofurans) are a class of man-made pollutants which are ubiquitously present in the environment. (springer.com)
  • The most well studied dioxin is called 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD). (healthed.govt.nz)
  • The most toxic compound is 2,3,7,8-tetrachlorodibenzo-p-dioxin or TCDD. (lbbs.org)
  • They are structurally comprised of two benzene rings joined by oxygen atoms, and they include these congeners: 10 dichlorodibenzo-p-dioxins (DCDD), 14 trichlorodibenzo-p-dioxins (TrCDD), and 22 tetrachlorodibenzo-p-dioxins (TCDD). (creationwiki.org)
  • A new study by Washington State University researchers found that TCDD dioxin, when exposed to one generation of pregnant rats, had a multi-generational effect resulting in a multitude of diseases. (beforeitsnews.com)
  • For this study, the researchers used a particular dioxin called TCDD-a major component of the herbicide Agent Orange made infamous by the Vietnam War as well as recent events in agribusiness . (beforeitsnews.com)
  • Carvan and his research team fed both young rainbow trout and zebrafish food containing different levels of TCDD (tetrachlorodibenzo- p -dioxin) over a six-week period. (wisc.edu)
  • Dioxins are highly poisonous chemicals that are everywhere in the environment. (medicalnewstoday.com)
  • In 1976, an industrial accident led to a cloud of toxic chemicals, including dioxins, affecting thousands of people in Italy. (medicalnewstoday.com)
  • According to the U.S. Environmental Protection Agency (EPA), dioxins a family of toxic chemicals that share a similar chemical structure and induce harm through a similar mechanism. (ewg.org)
  • Dioxins, Pesticides, and Fragrance Chemicals in Tampons? (mercola.com)
  • It's been shown to work quite well for some other kinds of chemicals, but not for the dioxins. (loe.org)
  • Dioxin is a general term that describes a group of 210 chemicals that are highly persistent in the environment. (environmental-expert.com)
  • Once called the deadliest of toxic chemicals, dioxin may be only a small hazard to human health and only a weak carcinogen if it is one at all. (chicagotribune.com)
  • Dioxins are toxic chemicals that naturally exist in the environment and can be released into the environment through forest fires, backyard burning of trash, certain industrial activities, and residue from past commercial burning of waste. (environmental-expert.com)
  • and Andrew C. Sigler, Champion International) thanked Reilly for his receptiveness to their ideas during the meeting January 23: "We were also encouraged by what we perceived as your willingness to move expeditiously to re-examine the potency of dioxin and chloroform in light of the important new information that has been submitted with respect to those chemicals," the paper company executives said. (ejnet.org)
  • The move comes after repeated requests from the environment council to subject dioxin and 21 other chemicals to immediate curbs under the Air Pollution Law. (japantimes.co.jp)
  • Dioxins are a group of chemicals. (healthed.govt.nz)
  • The Agriculture Department announced Thursday it will destroy all cattle at 21 farms that received feed contaminated by dioxins, a family of chemicals that can cause cancer if digested in sufficient quantity and duration. (manufacturing.net)
  • The Okinawa Defense Bureau recently found dioxin and other hazardous chemicals from barrels unearthed at a former U.S. military installation in the city of Okinawa, officials said Monday, suggesting they may have contained herbicides or agricultural chemicals. (fluoridealert.org)
  • Eggs with high dioxin levels were found in several German states because hens were allowed to roam on land contaminated with the chemicals. (thepoultrysite.com)
  • Dioxins belong to the persistent organic chemicals ("dirty dozen") the production and use of which was banned by the Stockholm Convention in 2001. (mondaq.com)
  • Dioxin is one of the most toxic chemicals known. (lbbs.org)
  • Average sperm counts of men living in the U.S. have fallen 50 percent since 1975, and while the link to dioxin may not yet be certain, no other family of chemicals is nearly as damaging or as pervasive. (social-ecology.org)
  • Though dioxins can be reduced they are very difficult to remove completely from a certain location because they are resistant to harmful chemicals . (creationwiki.org)
  • Because rainbow trout mature more slowly, the researchers were not able to determine TCDD's impact on that species' reproductive tract, but Carvan suspects that in areas where trout are exposed to significant amounts of dioxin or dioxin-like chemicals, their reproductive tracts would be impacted. (wisc.edu)
  • EWG research found that the amount of dioxin a nursing infant ingests daily is up to 77 times higher than the level the agency has defined as harmless to the endocrine and immune systems. (ewg.org)
  • Dr. Kimbrough said that the amount of dioxin an infant would acquire from the mother's milk would not be that much higher than it had already acquired in the mother's uterus. (nytimes.com)
  • Pretty scary stuff, and even scarier when you realize everyone eats a certain amount of dioxin every day. (huffingtonpost.com)
  • The amount of dioxin in a person's body naturally decreases over time. (healthed.govt.nz)
  • The amount of dioxin found ranged from 62 to 1,100 picograms per gram of sample. (fluoridealert.org)
  • Polychlorinated dibenzo-p-dioxins Polychlorinated dibenzofurans Polychlorinated biphenyls 1,4-dioxin Dioxins have different toxicity depending on the number and position of the chlorine atoms. (wikipedia.org)
  • There are 135 possible dibenzofurans, and 10 in which the lateral chlorines are dioxin-like. (wikipedia.org)
  • Dioxins, PCB's, dibenzofurans, and a variety of chemically-related pesticides are now widely recognized as "environmental hormones," which mimic the actions of vital molecular messengers in all living cells, and send systematically incorrect messages to every cell in every organ system of the body. (social-ecology.org)
  • Dioxins are highly toxic and can cause cancer, reproductive and developmental problems, damage to the immune system, and can interfere with hormones. (epa.gov)
  • Thursday, the state had announced that low levels of a highly toxic form of dioxin had been found in the ground water in one of the wells at the landfill - the first such discovery in Connecticut. (nytimes.com)
  • State tests revealed low levels - .00015 parts per billion - of a highly toxic form of dioxin in one of 12 areas sampled by the Department of Environmental Protection. (nytimes.com)
  • Open burning of trash is one of the leading sources of dioxins -- highly toxic pollutants that occur in the environment. (medindia.net)
  • Dioxin is highly toxic to some species of laboratory animals but far less so to others. (chicagotribune.com)
  • Dioxin is a highly toxic byproduct produced in the manufacture of many pesticides, and by the routine operation of all incinerators, metal smelters, and chlorine-using paper mills. (ejnet.org)
  • The Cabinet August 26 will take the nation's first step to deal with highly toxic dioxin emissions, which are 10 times higher here than in the U.S. or Europe. (japantimes.co.jp)
  • Polychlorinated dibenzo -p- dioxins (PCDDs), or simply dioxins. (wikipedia.org)
  • PCDDs are derivatives of dibenzo -p- dioxin . (wikipedia.org)
  • They include: Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. (wikipedia.org)
  • Analogously to PCDDs at least two lateral chlorines in each ring in positions 3,4, and/or 5 are needed for dioxin-like activity. (wikipedia.org)
  • Dioxins, a collective term for a group of environmental contaminants that includes certain dioxin, furan, and dioxin-like PCB (polychlorinated biphenyl) congeners, are found throughout the world. (fda.gov)
  • Call SGS today for a dioxin and furan analysis to ensure your site safety. (sgs.com)
  • Our dioxin and furan testing can identify where toxic emissions are occurring and help to improve the safety of your operations. (sgs.com)
  • We also monitor dioxin and furan levels in food and animal feed. (sgs.com)
  • Fully accredited at local and international level, we are recognized as one of the world's leading and most reliable laboratories for dioxin and furan testing. (sgs.com)
  • Continuous dioxin and furan emission monitoring by long-term sampling. (environmental-expert.com)
  • This book is a well organised treatise on identification and measurement of dioxins and furan in the environment. (routledge.com)
  • For references , please go to https://www.eea.europa.eu/data-and-maps/daviz/eionet/sandbox/LOT2%20-%20Daviz%20testing%20environment/change-in-dioxin-furan-emissions or scan the QR code. (europa.eu)
  • EPA's review found that the UMDES was well-suited to identify patterns of serum dioxin, furan and PCB levels among adults. (eponline.com)
  • Dioxins have different toxicity depending on the number and position of the chlorine atoms. (wikipedia.org)
  • EWG has submitted its analyses and recommendations to EPA's Science Advisory Board, which scheduled two public meetings in Washington in July and October 2010 to discuss EPA's long-awaited "Reanalysis of Key Issues Related to Dioxin Toxicity. (ewg.org)
  • They do not reach concentrations causing typical dioxin-like toxicity, however. (wikipedia.org)
  • By April, 1991, Reilly had geared up his agency for a major effort to reassess the toxicity of dioxin, just as the paper industry had requested. (ejnet.org)
  • 1. The EPA, in 1994, re-assessed the toxicity of dioxin, and confirmed the finding that it was the most toxic organic chemical known, with measurable health effects in our bodies at levels of as little as 10-15 ppt, cumulative over a lifetime. (lbbs.org)
  • In 1991, paper manufacturers and other industries pressured the EPA to undertake a systematic reassessment of the toxicity of dioxins, confident that the data could be found to justify a weakening of dioxin-based regulations. (social-ecology.org)
  • Fatty foods such as meat, poultry, seafood, milk, egg and their products are the major dietary sources of dioxins. (gov.hk)
  • Waste incinerators are common sources of dioxins, which form when paper, wood, and vinyl-based plastics are burned together. (social-ecology.org)
  • In the last 30 years, the Environmental Protection Agency (EPA) and other bodies have reduced the production of dioxin levels in the U.S. by 90 percent . (medicalnewstoday.com)
  • Plants, water, and air all contain low levels of dioxins. (medicalnewstoday.com)
  • Volcanoes, forest fires, and other natural sources have always given off dioxins, but in the 20th century, industrial practices have caused the levels to rise dramatically. (medicalnewstoday.com)
  • In 2008, contaminated animal feed led to pork products from Ireland containing over 200 times the permitted levels of dioxins. (medicalnewstoday.com)
  • Nine animal studies conducted between 1973 and 2008 show that dioxin is harmful at levels even lower than in the human studies on which EPA based its proposal. (ewg.org)
  • Even if all human-generated dioxins were eliminated, low levels of naturally produced dioxins would remain. (epa.gov)
  • The crisis involved food oil, used as an additive for numerous products, that was found to contain dangerously high levels of dioxins. (ift.org)
  • On July 1, the European Union acted to mitigate these risks by imposing tough limits on the levels of dioxins in food and feed. (ift.org)
  • Therefore, U.S. food exporters must begin testing their products before shipping them to the EU to ensure safe levels of dioxin and to stave off European regulatory action. (ift.org)
  • Screens identify whether or not dioxin levels meet EU criteria at a much lower cost than full-blown analytical tests, which provide more information than the EU requires. (ift.org)
  • Now that the EU has set the global standards for dioxin levels in food, should the U.S. government follow suit? (ift.org)
  • More recently, USDA's Food Safety and Inspection Service began testing meat and poultry to determine if dioxin levels in these products are above acceptable limits. (ift.org)
  • For years, environmentalists in Michigan have been pressuring the state to clean up what they say are dangerous levels of dioxin in the soil of Midland, where Dow Chemical Company is headquartered. (loe.org)
  • Years ago, soil sampling in Midland, Michigan revealed high levels of dioxin on the grounds of Dow Chemical and in nearby playgrounds and parks. (loe.org)
  • The levels of dioxin are thousands of times lower than those found in Times Beach, Mo. (nytimes.com)
  • Tests of residents' well water revealed high levels of certain industrial wastes, although no traces of dioxin. (nytimes.com)
  • Using research that ranged from satellite imagery to soil sampling, the firm found high levels of dioxin, an Agent Orange component, in the blood of Vietnamese born after the war, indicating that contaminants are being transferred through the food chain. (latimes.com)
  • Dioxin is also found in high levels in fish and animal tissue. (latimes.com)
  • This is despite the fact that dioxin levels have decreased in recent years in all countries for which data for the last 10 to 15 years are available. (europa.eu)
  • While it took an exceptionally high dose (1000 times the normal levels) to poison Mr Yuschenko the fact that we consume tiny amounts of dioxin everyday in the food we eat is frightening enough. (greenpeace.org)
  • Recently, the NHANES study in the U.S. showed striking dose-response relationships between the prevalence of diabetes and serum levels of six POPs, including PCB 153, dioxins, and organochlorine pesticides (OCPs) ( 11 ). (diabetesjournals.org)
  • Soot from wood smoke contains high levels of dioxin. (japantimes.co.jp)
  • The concentrations of all of the PCDD/F and PCB congeners were summed to give overall dioxin levels. (foodstandards.gov.au)
  • To investigate the role of hsp90 in dioxin signaling we have studied receptor function in a yeast strain where hsp90 expression can be down-regulated to about 5% relative to wild-type levels. (pnas.org)
  • At low levels of hsp90, ligand-dependent activation of the chimeric dioxin receptor construct was almost completely inhibited, whereas the activity of a similar chimeric construct containing the structurally related Arnt factor was not affected. (pnas.org)
  • Moreover, a chimeric dioxin receptor construct lacking the central ligand- and hsp90-binding region of the receptor showed constitutive transcriptional activity in yeast that was not impaired upon down-regulation of hsp90 expression levels. (pnas.org)
  • According to regulations of the European Commission, the executive arm of the European Union, maximum emission levels of dioxin should not exceed 0.1 ng/m3. (globalissues.org)
  • But, if dioxin levels were too high in 2007 at three plants, when did the dioxin pollution begin? (globalissues.org)
  • A study of breast milk from 50 mothers around the nation has found relatively high average levels of the toxic substance of dioxin, the study's author reported today. (nytimes.com)
  • Scientists at the environmental agency said that they were not surprised by the report because the levels of dioxin in the milk of American mothers was similar to that previously reported in studies in other industrialized countries and by the World Health Organization. (nytimes.com)
  • They said that the levels were consistent with studies conducted here of dioxin in body tissue. (nytimes.com)
  • Twenty years ago, it was first reported that men that had been exposed to high levels of dioxin as a result of an industrial accident in Seveso, Italy, on average fathered less boys than girls compared to men exposed to background levels of dioxin," said lead study author Andrea 't Mannetje, a public health researcher at Massey University in Wellington, New Zealand. (reuters.com)
  • In Hong Kong , the Food and Environmental Hygiene Department initiates follow up action for foods found to contain high levels of dioxins in the food surveillance program. (gov.hk)
  • The feds have further identified the highest levels in fish, followed by eggs, and then cheese, as Dr. Michael Greger* explains in his scary "Dioxins in the Food Supply" video . (huffingtonpost.com)
  • Consumed at high levels, dioxins are linked to various human ailments including reproductive problems and cancer. (huffingtonpost.com)
  • Meat with high levels of dioxin had been put on the market, including outside of Iceland, the country's Food and Veterinary Authority said, adding that it had launched an investigation into the matter. (medindia.net)
  • If the FDA doesn't believe the levels of dioxin in the affected chicken, eggs and catfish pose no risk, why are they requiring the poultry industry to test their products? (essential.org)
  • Fewer than 20 laboratories in the nation can test for such small levels of dioxin. (essential.org)
  • CRE is informed that the Risk Assessment may state that dioxin has adverse effects at or below background levels. (thecre.com)
  • Everyone has some dioxins in their body but levels in the general population are decreasing. (healthed.govt.nz)
  • Previous studies of the New Zealand population show that dioxin levels have dropped by as much as 70 percent in the ten years from the late 1980s. (healthed.govt.nz)
  • Dioxin levels in the environment peaked in the 1960s and '70s and have been declining since, according to studies . (cnn.com)
  • Ireland found much higher levels of cancer-causing dioxins in cattle than previously forecast, but insists the problem has been contained and poses no risk to beef-eaters. (manufacturing.net)
  • The Food Safety Authority of Ireland says it has found dioxin levels 100 to 400 times higher than legal limits in cattle at four farms. (manufacturing.net)
  • But although health experts say the dioxin found in German eggs was at levels too low to pose a threat to human health, the levels nevertheless exceeded government-set limits and have touched off a scare that Germany is still trying to contain. (foodsafetynews.com)
  • Elevated dioxin levels in and along the Tittabawassee River and downstream appear to be primarily attributable to liquid wastes that were discharged in the past directly into the river from the facility. (mlive.com)
  • It is uncertain how well the study represented people who participate in activities that could lead to elevated dioxin exposures, such as eating local fish and game with elevated dioxin levels. (eponline.com)
  • Thus, the UMDES data do not support analysis of the association between dioxin blood levels and possible health effects. (eponline.com)
  • Among the study's other findings: people living in the Midland-Saginaw area have higher blood dioxin levels than those in the reference area and national averages, and that properties in Midland-Saginaw tend to have higher soil dioxin levels than in the reference area. (eponline.com)
  • As has been found in other studies, it also found that higher blood dioxin levels were associated with demographic factors such as increased age, dietary choices and being overweight. (eponline.com)
  • The Minister for the Environment intends to launch an investigation into the causes and implications of high levels of dioxin in certain areas of Iceland. (grapevine.is)
  • Although health authorities believe the levels of dioxin ingested by people exposed to the chemical so far are not high enough to cause any health problems, the matter is still of grave concern to the government. (grapevine.is)
  • It shows that dioxin levels in food and feed are continuing to gradually drop, likely due to the spread and enforcement of stricter food standards and air emission controls. (mondaq.com)
  • The report contains one discouraging note: dioxin levels are higher in wild fish than in farmed fish, and higher in free range eggs than in battery eggs. (mondaq.com)
  • In the period 1987−1991 a cohort of mother−baby pairs was initiated to detect abnormalities in relation to dioxin levels in the mother's milk. (uva.nl)
  • Similarly, we found no relation between prenatal, nor current, dioxin levels and the hematological and the immunological parameters determined. (uva.nl)
  • Animals from a farm in whose pigs high levels of dioxin had been found were known to have been sent for slaughter in December before the closures were imposed. (thepoultrysite.com)
  • The local German agriculture ministry says illegal levels of dioxin were found in a pig farm. (organicauthority.com)
  • At doses already found in the fatty tissues of people all over the world, dioxins and related endocrine disrupters can alter levels of sex hormones, impair immune system function ("chemical AIDS" is a name given to dioxin in some quarters), reduce sperm counts, disturb fetal development -especially the proper development of sex organs-and increase the likelihood of learning disabilities. (social-ecology.org)
  • Through incineration and combustion, huge levels of dioxin disperse throughout the atmosphere . (creationwiki.org)
  • Some illnesses connected to inhalation of the levels of Dioxin are lung cancer, soft-tissue sarcomas, lymphomas, and stomach carcinomas. (creationwiki.org)
  • Dioxin Levels in Food - Where's the Beef? (chej.org)
  • This is remarkable because the EPA's health assessment on dioxin adds an important piece of new information that answers the question about the levels of dioxin in the American food supply. (chej.org)
  • This estimate was based on an EPA estimate of dioxin levels in food. (chej.org)
  • It is clear however that large numbers of the U.S. population, especially children, are being exposed to dioxin in food at levels that exceed EPA's reference dose. (chej.org)
  • We need to stop pretending that dioxin levels in food are not a problem and take this issue on. (chej.org)
  • We need better data on dioxin levels in food and how it gets there, and for EPA, FDA, and USDA to engage in this issue. (chej.org)
  • If I were looking at the effects of low levels of dioxin, I would absolutely investigate the nasal epithelium and gonad development," Carvan said. (wisc.edu)
  • Sometimes described as the most toxic contaminant ever found, dioxin has been linked to multiple outbreaks of disease and cancer triggered by high-level exposures at least as far back as 1949. (ewg.org)
  • EPA's "reanalysis" noted that these low-level exposures are all but unavoidable because dioxins are widespread in the environment, break down very slowly, build up in the food chain and accumulate in the tissues of animals, especially in fat. (ewg.org)
  • As a consequence, exposures begin in the womb when dioxins cross the placenta, and newborn infants begin to ingest them from the very first days of life. (ewg.org)
  • In fact, a large part of current exposures to dioxins in the United States is due to releases that occurred decades ago (e.g., pollution, fires). (epa.gov)
  • In 2009, former Administrator Lisa Jackson directed EPA to accelerate work underway to reassess the human health risks from exposures to dioxin. (epa.gov)
  • They told Reilly there is now a "prevailing view that low-level dioxin exposures do not pose a serious health threat. (ejnet.org)
  • They excluded studies of leather, flavor, and fragrance workers, whose occupational exposures typically include not only dioxin but also cardiotoxic methylmercury, arsenic and xylene. (innovations-report.com)
  • METHODS: We examined death rates among 773 workers exposed to chlorinated dioxins during PCP manufacturing from 1937 to 1980 using serum dioxin evaluations to estimate exposures to five dioxins. (biomedsearch.com)
  • EPA has argued for some time that dioxin exposures are going down and in 2009 EPA published a paper that estimated the daily average intake of dioxin to be only 0.54 pg TEQ/kg/day. (chej.org)
  • Learn more about dioxin in drinking water from this table of regulated drinking water contaminants . (epa.gov)
  • We are at the forefront of the development and application of methods indicating the presence of contaminants such as dioxins. (wur.nl)
  • Occasionally we detect concentrations in excess of the norm, in which case we immediately take action to determine the source of the dioxins to prevent any further spread of the contaminants. (wur.nl)
  • RMP studies of contaminants in Bay sport fish conducted every three years since 1994 have found that dioxin concentrations have remained unchanged over this time period and in some species, continue to greatly exceed screening values for human consumption. (sfei.org)
  • CONCLUSIONS: Other than possibly an increased risk of non-Hodgkin lymphoma, we find no other cause of death related to the mixture of the dioxin contaminants found in PCP. (biomedsearch.com)
  • Starting from 1999, the Food and Environmental Hygiene Department has been monitoring dioxins in foods. (gov.hk)
  • TOOMEY: Under Michigan law, dioxin soil concentrations greater than 90 parts per trillion may indicate a possible health hazard. (loe.org)
  • Overall, the concentration of dioxins in the surveyed foods was very low with the highest mean PCDD/F concentrations being found in peanut butter (0.035-0.235 pg TEQ/g fresh weight, lower to upper bound), butter (0.010-0.20 pg TEQ/g fresh weight) and fish fillets (0.08-0.13 pg TEQ/g fresh weight). (foodstandards.gov.au)
  • Our understanding of dioxin in the Bay is extremely limited, however, and improving this is a necessary first step in reducing concentrations in Bay fish and resultant health risks to fish-eating humans and wildlife. (sfei.org)
  • Have dioxin loadings/concentrations changed over time? (sfei.org)
  • Serum Dioxin Concentrations and Endometriosis: A Cohort Study in Seveso, Italy. (questia.com)
  • But on Sunday the EU Commission acknowledged that three chickens out of several samples it had tested showed dioxin concentrations of twice the legal limit, a British newspaper, the Telegraph, reported. (foodsafetynews.com)
  • The study included more than 900 participants and provided estimates of the distributions of dioxin concentrations in blood, soil and dust in the Midland-Saginaw area as well as a reference area for comparison 100 miles to the south. (eponline.com)
  • Dioxins have been found to cause cancer in laboratory animals at concentrations of only a few parts per trillion, a fact widely used by activists to press for more stringent regulation of incinerators and other industrial sources. (social-ecology.org)
  • Drinking water can contain dioxins if it has been contaminated by chemical waste from factories, or by other industrial processes. (medicalnewstoday.com)
  • Those human studies, conducted in 2008, explored the toxic legacy of a 1976 chemical plant explosion in Seveso, Italy, which exposed thousands of people to dioxin in unprecedented intensity and left large quantities of the chemical in the soil. (ewg.org)
  • And dioxins from its chemical plant came from making such products as saran wrap, Agent Orange, and various pesticides. (loe.org)
  • The deadly chemical dioxin has hit the headlines with the poisoning of Ukrainian opposition leader Viktor Yuschenko. (greenpeace.org)
  • Almost everyone has some level of dioxin in their blood because the toxic chemical is widespread in the environment and accumulates in the food chain. (greenpeace.org)
  • Dioxin is formed as an unintentional bi-product of many industrial processes involving chlorine, such as waste incineration, chemical and pesticide manufacturing, and pulp and paper bleaching. (environmental-expert.com)
  • Dioxins are extremely toxic chemical substances which can be transmitted into our food through the environment. (wur.nl)
  • When the 2 factories closed in the 1980s, they left a toxic stew that includes wood preservatives, pesticides, and dioxin, a chemical by product of many industrial processes. (loe.org)
  • Dioxin is one of the most toxic chemical substances known to man. (loe.org)
  • LIMA, Peru -- Traces of the cancer-causing chemical dioxin were found in 128 tons of powdered milk imported from Belgium and destined for a food program feeding poor schoolchildren, said Peruvian health officials this week. (wsj.com)
  • The dioxin came from a Dow chemical plant. (environmentreport.org)
  • Reuters Health) - Men exposed to dioxin, a chemical once common in herbicides, may be less likely to father boys than peers who didn't come in contact with this toxin, a recent study suggests. (reuters.com)
  • Thousands of ducks and a million duck eggs have been destroyed after the toxic chemical dioxin was found in eggs at a supermarket, the government said yesterday. (taipeitimes.com)
  • Dioxin is a toxic chemical that persists in the environment and is believed to cause cancer and birth defects. (taipeitimes.com)
  • Under the new rules, dioxin, a toxic chemical often detected in the vicinity of waste incinerators, will be designated as hazardous under the Air Pollution Law. (japantimes.co.jp)
  • An appeals court ruling has cleared the way for Harris County Attorney Vince Ryan's legal team to proceed with a lawsuit alleging that the San Jacinto River has been polluted with the dangerous chemical dioxin. (chron.com)
  • The County alleges that in the 1960s huge quantities of paper mill waste containing dioxin, the most poisonous chemical made by man, were dumped into pits along the river. (chron.com)
  • The agency's plans to quantify dioxin risks has pitted environmental groups, parent organizations and Vietnam veterans in favor of an assessment against the agriculture, food and chemical industries , which say the EPA report is unnecessary and will hurt businesses by triggering unfounded fears. (cnn.com)
  • Most of what you read is rubbish, propaganda put out by the chemical companies, 2,4,5-T and 2,4D are the main sources of Dioxin in the food chain! (foodsafetynews.com)
  • As has been reported, dioxin - a toxic chemical compound that was used among other applications to make the notorious herbacide Agent Orange - was first discovered in milk from the West Fjörds in December. (grapevine.is)
  • GERMANY - Germany has called for higher environmental standards on farms after free-range eggs were found to contain the cancer causing chemical dioxin. (thepoultrysite.com)
  • Dioxin is probably the single most toxic chemical consequence of all of Louisiana's-and the world's-industrial excess. (social-ecology.org)
  • For this reason, large amounts of dioxin have been exposed to the environment unintentionally as by-products of other chemical processes. (creationwiki.org)
  • Dioxin is used only in chemical research. (creationwiki.org)
  • Since 1945, Monsanto and Dow have sprayed 300 million pounds of dioxin-containing herbicides on 400 million acres of American land, which explains why the chemical is even found in animal products like eggs, dairy, and meat. (beforeitsnews.com)
  • The final review of the Paritutu dioxin serum study is expected to be released early next month. (nzherald.co.nz)
  • People can have their blood serum tested to see how much dioxin it contains today. (healthed.govt.nz)
  • Serum dioxin tests cannot predict if you will develop a disease, or the outcome of a disease that a person currently has. (healthed.govt.nz)
  • Enacting standards to match the EU standards would not only protect the general population from the health dangers of dioxins, but would also protect the food industry from the financial and public relations repercussions of a major dioxin scare. (ift.org)
  • The company, based in Uetersen, north-west of Hamburg, is under investigation by prosecutors and could also potentially face vast civil claims from 5,000 German farms that were closed down during the dioxin scare. (thepoultrysite.com)
  • The dioxin scare surfaced after 3,000 tonnes (over 6,600 pounds) of an animal feed additive sold in Germany were discovered to contain trace amounts of dioxin, leading officials to ban over 1,000 farms from selling eggs. (organicauthority.com)
  • And what they found that, lo and behold, only about 25 percent of the dioxin was actually extractable in the conditions of the human stomach. (loe.org)
  • The level of dioxin found is so little, it's like a shot glass of vermouth in 50,000 boxcars of gin,'' he said. (nytimes.com)
  • The Jones County jury found that DuPont "negligently released dioxins and arsenic from the DeLisle facility" but did not link the release to the death of the Ladners' daughter. (insurancejournal.com)
  • Another jury in Mississippi has found DuPont negligently releases dioxins and arsenic from its DeLisle facility," he said. (insurancejournal.com)
  • Tests have found people who lived near the Ivon Watkins-Dow factory which made 245-T from 1962 to 1987 had up to seven times more dioxin in their blood than other people. (nzherald.co.nz)
  • The four executives memorialized their meeting by sending Reilly a letter dated January 25th --a letter that (thanks to Greenpeace) found its way into the record of a public hearing on the dioxin reassessment which EPA held in Washington, D.C. November 15, 1991. (ejnet.org)
  • But since dioxin was found in the milk, we have stopped eating our produce,' he said. (globalissues.org)
  • Still, the findings add to results from research at the accident site in Italy, that also found the decrease in male births was more pronounced when people were exposed to larger amounts of dioxin, said Michele Marcus, a public health researcher at Emory University in Atlanta who wasn't involved in the New Zealand study. (reuters.com)
  • That's because dioxins are found in meat and dairy products, and most other foods. (huffingtonpost.com)
  • EDT) -- Temporary shutdowns at poultry plants idled hundreds of workers after federal inspectors found that dioxin-contaminated feed had been used by farmers producing chicken, eggs and catfish. (essential.org)
  • The Canadian study revealed that the level of dioxin found in cheese was 250% higher than that permitted by WHO. (notmilk.com)
  • More detailed information can be found in the book Dying From Dioxin by Lois Gibbs. (lbbs.org)
  • Dioxin was the primary toxic component of Agent Orange, was found at Love Canal in Niagara Falls, NY and was the basis for evacuations at Times Beach, MO and Seveso Italy. (lbbs.org)
  • Dioxin can also be found in natural fires. (creationwiki.org)
  • For example, a 2003 study by the National Academy of Science s Committee on Dioxin in Food found that children ages 1 to 5 were exposed to 1.09 pg TEQ/kg/day and children ages 6-11 years old were exposed to 0.69 pg TEQ/kg/day. (chej.org)
  • A recent research paper found that the average daily intake of dioxin in 207 pre-school aged children was 1.01 pg TEQ/kg/day, well above the EPA reference dose of 0.7 pg /kg day. (chej.org)
  • Carvan said the amounts of dioxin they exposed the fish to were, "high for the average fish in Lake Michigan, but they're not necessarily that high for a fish found in a polluted environment. (wisc.edu)
  • There are 75 possible congeners of polychlorinated dibenzo-p-dioxins, but only 7 of them have affinity for the AH receptor and are toxic via this mechanism. (wikipedia.org)
  • Dioxin has been linked to a range of health effects, including cancer and reproductive damage. (loe.org)
  • As a result, EPA scientists concluded a year ago that dioxin probably causes cancer in wildlife and humans, and that it harms the immune system and the reproductive systems in fish, birds, and mammals (including humans) at doses that are miniscule. (ejnet.org)
  • In addition, the receptor seems to mediate by as-yet-unresolved mechanisms a wide range of toxic effects by dioxins including birth defects, impaired reproductive capacity, and immune suppression ( 1 ). (pnas.org)
  • They also stressed that dioxin causes health problems other than cancer, including damage to the reproductive and immune systems. (nytimes.com)
  • Not only can dioxins and a wide variety of related substances cause cancer at extremely minute doses, but they have widespread damaging effects on the reproductive, immune, and nervous systems of people and animals. (social-ecology.org)
  • Dioxin is an industrial pollutant linked to cancer and reproductive disorders. (beforeitsnews.com)
  • According to EPA's 2006 Dioxin Inventory of Sources Report man-made emissions, including backyard and household trash burning, dominated releases in the United States. (epa.gov)
  • The GT90 Dioxin+ is designed specifically for long-term monitoring of dioxin emissions. (environmental-expert.com)
  • It is scheduled to adopt revised administrative ordinances for enforcing the Air Pollution Law and the Wastes Disposal and Public Cleaning Law, moves intended to curb high emissions of dioxin, an administrative vice ministerial meeting said August 25. (japantimes.co.jp)
  • It is hoped that the step will cut dioxin emissions by 90 percent within five years. (japantimes.co.jp)
  • Nature can produce dioxin-such as through volcanoes and forest fires-but human activities by far result in more emissions. (beforeitsnews.com)
  • The primary source of dioxin in most residential communities, and a growing concern, is wood smoke. (japantimes.co.jp)
  • What is the relative contribution of each loading pathway as a source of dioxin impairment in the Bay? (sfei.org)
  • The major source of dioxin in the environment (95%) comes from incinerators burning chlorinated wastes. (lbbs.org)
  • Monsanto and Dow herbicides, which the EPA has admitted as being the seventh greatest source of dioxin in the U.S. (beforeitsnews.com)
  • Over the past decade, EPA and industry have been working together to dramatically reduce the production of dioxin and its release to the environment. (epa.gov)
  • Paper manufacturers that use chlorine dioxide in their processes brought dioxin to surface water , but since then, guidelines have been put into motion to stop and reduce the production of dioxin now and later in the future. (creationwiki.org)
  • Cigarette smoke also contains small amounts of dioxins. (medicalnewstoday.com)
  • Small amounts of dioxin, which is an industrial waste product, are believed to cause no harm, but the body collects dioxin throughout life, and it is suspected of causing cancer in higher doses. (thepoultrysite.com)
  • Various amounts of Dioxin have a large effect on animals as well as humans. (creationwiki.org)
  • Executive Summary of the Assessment of the health risk of dioxins : re-evaluation of the Tolerable Daily Intake (TDI) produced in 1998. (greenfacts.org)
  • It`s true there are fresh data to support the revised assessment of dioxin. (chicagotribune.com)
  • Today the U.S. Environmental Protection Agency (EPA) finalized its non-cancer science assessment for dioxins, which was last reviewed in the 1980s. (environmental-expert.com)
  • In August, just 4 months into the multi-year study, Reilly told the NEW YORK TIMES how he expected the dioxin reassessment to turn out: "I don't want to prejudge the issue, but we are seeing new information on dioxin that suggests a lower risk assessment for dioxin should be applied," Reilly told the TIMES (August 15, 1991, pg. (ejnet.org)
  • The U.S. Environmental Protection Agency missed its self-imposed deadline to complete a dioxin health assessment by the end of January. (cnn.com)
  • The EPA planned to release a non-cancer health assessment of dioxin by January 31, with the cancer assessment following soon after. (cnn.com)
  • Another delay is unfortunate, but it is clear that the EPA has more work to do in order for the agency to release a complete and scientifically defensible dioxin assessment,' the American Chemistry Council, an industry group, said in a statement. (cnn.com)
  • Last year the USEPA completed and published the non-cancer portion of its health assessment for dioxin, one of the most toxic substances ever tested.This event passed without much fan-fare and little coverage by the media. (chej.org)
  • And there are other ways to be exposed to dioxin in soil, including inhalation and absorption through the skin, although Dow also downplays the dangers posed by those pathways. (loe.org)
  • In 1991, the Environmental Protection Agency used its emergency powers under the Federal Superfund Law, and began digging up dioxin-contaminated soil at one of the abandoned factories. (loe.org)
  • Today the area is known as Mount Dioxin, a reference to the huge pile of contaminated soil left behind. (loe.org)
  • A study done in the area suggests dioxin in soil might not be getting into people living there. (environmentreport.org)
  • To understand what's at stake over the science of dioxin and soil, I want to talk with Marcia Woodman. (environmentreport.org)
  • You see, eight years ago, the state tested soil for dioxin. (environmentreport.org)
  • So, Woodman worried dioxin might move from soil into her kids, and maybe they'd get cancer or some other disease. (environmentreport.org)
  • But, what if dioxin in soil is not getting into people nearby? (environmentreport.org)
  • The government's limit for dioxin 1,000 picograms per gram of soil. (fluoridealert.org)
  • As for soil samples taken from the site, none exceeded the government's dioxin limit, the bureau said. (fluoridealert.org)
  • Also, the site specific data collected by the study will not be relevant as EPA revises its national interim preliminary remediation goals for dioxin in soil. (eponline.com)
  • This action causes dioxin to pervade into soil and sediments in water. (creationwiki.org)
  • In the United States (U.S.), dioxins are not produced or used commercially, but they may result as a byproduct of other processes. (medicalnewstoday.com)
  • Chlorinated dioxins form as an unintended byproduct of waste incineration and a variety of industrial processes, including smelting, chlorine paper bleaching and pesticide manufacturing. (ewg.org)
  • Dioxin was a byproduct of the process, it said. (fluoridealert.org)
  • Researchers already know that dioxin (a byproduct of burned plastics and industrial processes) is toxic and can contribute to cancer and heart problems in humans, but now they know it can impact a fish's nose tissue. (wisc.edu)
  • USDA, with its government partners FDA and EPA, conducts periodic monitoring surveys for dioxins in meat and poultry. (usda.gov)
  • The recent dioxin crisis has left the shelves in the popular Bio Company store in Berlin's Kreuzberg district, virtually bare, as demand for organic meat and egg spikes suddenly. (medindia.net)
  • Yes, 90% of the dioxin you're exposed to is through meat and dairy products. (lbbs.org)
  • Known as persistent environmental pollutants (POPs), dioxins can remain in the environment for many years. (medicalnewstoday.com)
  • Dioxins are called persistent organic pollutants (POPs) , meaning they take a long time to break down once they are in the environment. (epa.gov)
  • People calling themselves "conservatives" in Congress are preparing to flay U.S. Environmental Protection Agency (EPA) scientists for their reassessment of dioxin --the agency's 4-year effort to determine the true hazards of dioxin. (ejnet.org)
  • As the agency moved to enforce those limits in the late 1980s, industrial dioxin-producers developed a strategy for reversing EPA's stance: They would force the agency to undertake a scientific reassessment of dioxin, a reassessment they evidently thought they could control. (ejnet.org)
  • As a direct result, EPA's "scientific reassessment" of dioxin was born. (ejnet.org)
  • The lead scientist on the EPA reassessment team, Dr. Linda Birnbaum, said she and her colleagues now consider dioxin an "environmental hormone" capable of disrupting a large number of bodily processes in fish, birds, and mammals, including humans. (ejnet.org)
  • at an SAB meeting May 16, 1995, parts of the dioxin reassessment were criticized. (ejnet.org)
  • Plaintiffs and EPA have agreed to settle the legal challenge to the agency's Dioxin Reassessment. (thecre.com)
  • With this litigation-related barrier removed, EPA may move rapidly to release the final Dioxin Reassessment for interagency review. (thecre.com)
  • The Chairman of EPA's Appropriations Committee in the House has requested that the agency defer release of the Dioxin Reassessment until the National Academy of Sciences has had time to complete an important related study. (thecre.com)
  • CRE Advisory Board Member Jim Tozzi and other plaintiffs filed suit against EPA October, 27, 2000, in a challenge to the agency s use of draft guidelines for carcinogen risk assessments, including the forthcoming and controversial EPA Dioxin Reassessment. (thecre.com)
  • The second action is EPA s reliance on the newer guidelines to support the agency s controversial dioxin reassessment. (thecre.com)
  • When dioxins enter the food chain, they are stored in animal fats. (medicalnewstoday.com)
  • Dioxin-related food safety disasters have regularly cropped up in the media over the past decade. (ift.org)
  • The U.S. does not enforce dioxin limits in food or feed-a curious situation, given the pervasiveness of this potent toxin. (ift.org)
  • EPA, the U.S. Dept. of Agriculture, and the Food and Drug Administration have noted that EU dioxin testing and the probability of penalties for U.S.-based food exporters will likely increase over the next few years. (ift.org)
  • The new regulations affect a big business: the U.S. exported more than $3.5 billion worth of food to the EU in 2000 and 14,171 metric tons of dairy products high in fat-and therefore potentially high in dioxin-in 2001. (ift.org)
  • Most food producers and exporters in the U.S. do not currently test for dioxins. (ift.org)
  • In addition, FDA, EPA, and the National Academy of Sciences are all examining dioxins in the food supply. (ift.org)
  • While the U.S. food industry may fear the financial impact of dioxin regulations, such laws are necessary to protect the health of both the population and the food industry itself. (ift.org)
  • Dioxins are extremely stable and consequently tend to accumulate in the food chain. (wikipedia.org)
  • Wageningen Food Safety Research is specialised in dioxins research. (wur.nl)
  • Wageningen Food Safety Research conducts research for the presence of dioxins in foods commissioned by the Dutch government or the business community. (wur.nl)
  • Dioxins enter the food chain when animals eat contaminated plants. (foodstandards.gov.au)
  • The dioxins are then absorbed into the animal fat, increasing in concentration as they migrate up the food chain. (foodstandards.gov.au)
  • Photo Gallery: Analysis of food for toxins or Dioxin, poultry giblets Author: Martin MoxterDate: 2010-11-24 Royalty Free photo versions - Maximum available. (tradebit.com)
  • Dioxin is an accumulative toxin and is not considered to be particularly toxic to humans unless a lot of produce containing it is consumed - as could well be the case for farmers, who tend to eat a lot of home-produced food. (globalissues.org)
  • Dr. Shecter said that the dioxin in mothers' milk came largely from food. (nytimes.com)
  • Dioxin tends to accumulate in the food chain and build up in the flesh of fish and cattle. (nytimes.com)
  • Some dioxin-related food crises occurred in overseas countries have raised considerable public attention and concern. (gov.hk)
  • In Hong Kong , the situation of dioxins in foods has been closely monitored by the Food and Environmental Hygiene Department. (gov.hk)
  • There is no international consensus on standard of dioxin level in food. (gov.hk)
  • Dietary intake of dioxins is estimated by assessing the level of dioxins in food and food consumption pattern of the population. (gov.hk)
  • Individual food item exceeding action level of dioxin monitoring does not imply presence of immediate health hazard. (gov.hk)
  • Unfortunately for the food industry, dioxins accumulate in the fatty tissues of animals that Americans consume. (huffingtonpost.com)
  • Animals absorb dioxin, which occurs naturally in the environment and moves through the food chain via the food animals consume, especially forages. (huffingtonpost.com)
  • a lobbying group, complete with the Orwellian name: The Food Industry Dioxin Working Group. (huffingtonpost.com)
  • Further, Steve Kopperud, coordinator for the Food Industry Dioxin Working Group is afraid the media will have a field day with the EPA limits. (huffingtonpost.com)
  • The U.S. Food and Drug Administration stressed that the dioxin was not enough to endanger consumers. (essential.org)
  • The Centre for Food Safety (CFS) has analysed different kinds of food samples (including crabs) for dioxins under its Total Diet Study and the report was released in 2011. (gov.hk)
  • Most dioxins are byproducts of industrial processes and get into the food chain, where they accumulate in fatty tissue. (cnn.com)
  • About 3,000 German farms were given the go-ahead to resume making food deliveries as an investigation continues into how dioxin got into animal feed and eggs, the BBC reported Sunday. (foodsafetynews.com)
  • Last week, Britain's Food Standards Agency warned consumers that some dioxin-tainted eggs might have been mixed with noncontaminated eggs to make liquid egg products used commercially in mayonnaise and cakes. (foodsafetynews.com)
  • But up to 6 million women either can't breastfeed, or don't produce enough milk for their child, and dioxin in our food chain may be to blame. (ecochildsplay.com)
  • 2. Beef is about the most dioxin-contaminated food, at about 1part per million million (or 1 picogram per gram of food). (lbbs.org)
  • Beef is the most dioxin-contaminated food according to EPA. (lbbs.org)
  • The government has repeatedly assured the public that there is no danger from the dioxin-contaminated food. (thepoultrysite.com)
  • When Dioxins enter the food chain , humans retain substances of it in their fatty tissue. (creationwiki.org)
  • Until publishing this report, EPA had sidestepped the question of setting a reference dose for dioxin because they knew if they did this, they could no longer deny the obvious - the average daily intake of dioxin in food exceeds our best measure of what's safe, EPA's reference dose. (chej.org)
  • Unfortunately, there is no consensus of how much dioxin exists in the food we eat. (chej.org)
  • Loss-of-function (gene-disruption) studies in mice have demonstrated that the AhR is involved in toxic effects of dioxins but have not yielded unequivocal results concerning the physiological function of the receptor. (pnas.org)
  • Dr. Shahare specializes in water quality monitoring and treatment for priority pollutants with special reference to pesticides, trihalomethanes, polychlorinated dioxins, and carbamates. (routledge.com)
  • Dioxins are mainly byproducts of industrial activities but can also be produced by natural events like volcanic eruptions and forest fires. (reuters.com)
  • A special version of the HYSPLIT model has been developed to simulate the atmospheric fate and transport of semivolatile pollutants such as PCDD/F (dioxin). (noaa.gov)
  • 2.1.2 What is the average intake of dioxins? (greenfacts.org)
  • The estimated dioxins intake is then compared with the PTMI established by JECFA to assess the associated health risk. (gov.hk)
  • Dividing this value by the average weight of an adult (70 kilograms), you get an average daily intake of dioxin of 0.94 TEQ pg/kg/d, 34% higher than the safe level. (chej.org)
  • There were about 1,000 parts per trillion of all forms of dioxin in the milk samples, Dr. Shecter said. (nytimes.com)
  • Despite this new reality," they said, "EPA has taken no tangible or timely steps to revisit its health criteria for dioxin, and has even failed to temper the Agency's zeal in acting on the worst risk estimates. (ejnet.org)
  • The agency's review was conducted under the dioxin science plan announced by Administrator Lisa P. Jackson this past May. (eponline.com)
  • The main characteristics of dioxins are that they are virtually insoluble in water but have a high affinity for lipids. (wikipedia.org)
  • Dioxins are virtually insoluble in water but have a relatively high solubility in lipids. (wikipedia.org)
  • Chlorine bleaching of pulp and paper and other industrial processes can create small quantities of dioxins in the environment. (epa.gov)
  • Dioxins have no technological or other use, but are generated in a number of thermal and industrial processes as unwanted and often unavoidable by-products. (europa.eu)
  • Dioxins are formed naturally and by some industrial processes. (healthed.govt.nz)
  • 2. How are humans exposed to dioxins? (greenfacts.org)
  • The authors wrote that future studies in both animals and humans should assess whether cardiovascular effects are present at environmentally relevant doses of dioxin. (innovations-report.com)
  • But officials maintain that the level of dioxin in the tainted eggs does not pose a real risk to humans. (organicauthority.com)
  • Serious health effects of Dioxin to humans can occur in several ways. (creationwiki.org)
  • According to University of Virginia biochemist Jennifer Wolstenholme (who was not involved in the study), humans and rats eliminate dioxin from their bodies differently. (beforeitsnews.com)
  • How can dioxin affect my health? (epa.gov)
  • Given the risks that dioxins pose to human health, it is remarkable that testing is just now being required. (ift.org)
  • Meanwhile, the Environmental Protection Agency is expected to soon release its long-awaited report on dioxin's health hazards, and by most accounts, it will say that dioxin is more dangerous than current regulations assume. (loe.org)
  • Because dioxins can be harmful to health, authorities have imposed emission limit values that need to be monitored. (environmental-expert.com)
  • The Infectious Disease Control division of the Directorate of Health has decided to monitor residents of Isafjordur, Kirkjubaejarklaustur, and Vestmannaeyjar for the presence of dioxin. (globalissues.org)
  • Dioxins are toxic byproducts of the manufacture of chlorine-based products, and some have been linked to cancer and other health problems. (chicagotribune.com)
  • According to the findings of the study, general population in Hong Kong would be unlikely to experience adverse health effects as a result of dioxins absorbed from our daily diet. (gov.hk)
  • Research shows that some dioxins have adverse health effects. (healthed.govt.nz)
  • How can dioxins affect my health? (healthed.govt.nz)
  • Shame on EPA Administrator Lisa Jackson for denying parents the information they need to protect their children from the health impacts of dioxin, said Lois Marie Gibbs, executive director of the Center for Health, Environment & Justice . (cnn.com)
  • A report released for public comment in September 1994 by the US Environmental Protection Agency clearly describes dioxin as a serious public health threat. (lbbs.org)
  • The public health impact of dioxin may rival the impact that DDT had on public health in the 1960's. (lbbs.org)
  • European health officials are now warning that the German dioxin outbreak may be worse than previously thought - extending beyond tainted eggs - and prompting some countries to take harsher action. (organicauthority.com)
  • This past March, Baton Rouge was the site of a gathering of nearly 600 anti-toxics and environmental justice activists, who met to plan a coordinated strategy against the growing threat of dioxin to public health and the environment. (social-ecology.org)