AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
Dimethyl SulfoxideMethionine Sulfoxide ReductasesCryoprotective AgentsLeukemia, Erythroblastic, AcuteOxidoreductasesDimethylformamideSolventsIron-Sulfur ProteinsSulfoxidesEthylene GlycolHydroxidesCryopreservationFriend murine leukemia virusLeukemia, ExperimentalSulfuric Acid EstersCell DifferentiationRhodobacter sphaeroidesFreezingMethionineKineticsDimethyl SuberimidateAcetamidesSafroleSulfidesPteridinesHydroxyl RadicalButyric AcidFormamidesPropylene GlycolMethanolOxidation-ReductionCell LineAnaerobiosisFree RadicalsButyratesAcetonitrilesGlycerolDimethyl AdipimidateDiapause, InsectMolybdenumTungsten CompoundsTissue PreservationTretinoinLeukemia, Promyelocytic, AcuteShewanella putrefaciensFenthionMolecular Sequence DataBenzidinesMagnetic Resonance SpectroscopyEscherichia coliMethylaminesTumor Cells, CulturedHL-60 CellsTetradecanoylphorbol AcetateCoenzymesErythropoiesisDiaminesHair Cells, AmpullaGlobinsWaterGranulocytesMetalloproteins16,16-Dimethylprostaglandin E2TungstenAcetoneEthylene GlycolsPterinsDose-Response Relationship, DrugHeminShewanellaGeotrichosisFree Radical ScavengersLeukemia, Myeloid, AcuteHydrogen PeroxideCell DivisionElectron Spin Resonance Spectroscopy
Dimethyl Sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Methionine Sulfoxide Reductases
Reductases that catalyze the reaction of peptide-L-methionine -S-oxide + thioredoxin to produce peptide-L-methionine + thioredoxin disulfide + H(2)O.
Cryoprotective Agents
Substances that provide protection against the harmful effects of freezing temperatures.
Leukemia, Erythroblastic, Acute
A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
Oxidoreductases
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Dimethylformamide
Solvents
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
Iron-Sulfur Proteins
A group of proteins possessing only the iron-sulfur complex as the prosthetic group. These proteins participate in all major pathways of electron transport: photosynthesis, respiration, hydroxylation and bacterial hydrogen and nitrogen fixation.
Sulfoxides
Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)
Ethylene Glycol
A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
Hydroxides
Inorganic compounds that contain the OH- group.
Cryopreservation
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
Friend murine leukemia virus
A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) producing leukemia of the reticulum-cell type with massive infiltration of liver, spleen, and bone marrow. It infects DBA/2 and Swiss mice.
Leukemia, Experimental
Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
Sulfuric Acid Esters
Organic esters of sulfuric acid.
Cell Differentiation
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Rhodobacter sphaeroides
Spherical phototrophic bacteria found in mud and stagnant water exposed to light.
Freezing
Liquids transforming into solids by the removal of heat.
Methionine
A sulfur-containing essential L-amino acid that is important in many body functions.
Kinetics
The rate dynamics in chemical or physical systems.
Dimethyl Suberimidate
The methyl imidoester of suberic acid used to produce cross links in proteins. Each end of the imidoester will react with an amino group in the protein molecule to form an amidine.
Acetamides
Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.
Safrole
A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
Sulfides
Chemical groups containing the covalent sulfur bonds -S-. The sulfur atom can be bound to inorganic or organic moieties.
Pteridines
Compounds based on pyrazino[2,3-d]pyrimidine which is a pyrimidine fused to a pyrazine, containing four NITROGEN atoms.
Hydroxyl Radical
The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.
Butyric Acid
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Formamides
A group of amides with the general formula of R-CONH2.
Propylene Glycol
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Methanol
A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
Oxidation-Reduction
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Cell Line
Established cell cultures that have the potential to propagate indefinitely.
Anaerobiosis
The complete absence, or (loosely) the paucity, of gaseous or dissolved elemental oxygen in a given place or environment. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Free Radicals
Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Butyrates
Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.
Acetonitriles
Compounds in which a methyl group is attached to the cyano moiety.
Glycerol
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
Dimethyl Adipimidate
Bifunctional cross-linking agent that links covalently free amino groups of proteins or polypeptides, including those in cell membranes. It is used as reagent or fixative in immunohistochemistry and is a proposed antisickling agent.
Diapause, Insect
Seasonal suspension of insect growth development. It can be either induced by environmental cues (e.g., PHOTOPERIOD) or as a facultative part of the life cycle in order to time development with seasonal changes.
Molybdenum
A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)
Tungsten Compounds
Inorganic compounds that contain tungsten as an integral part of the molecule.
Tissue Preservation
The process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Tretinoin
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
Leukemia, Promyelocytic, Acute
An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
Shewanella putrefaciens
A species of SHEWANELLA noted for its ability to reduce iron and manganese anaerobically.
Fenthion
Potent cholinesterase inhibitor used as an insecticide and acaricide.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Benzidines
Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.
Magnetic Resonance Spectroscopy
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Methylamines
Tumor Cells, Cultured
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
HL-60 Cells
A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)
Tetradecanoylphorbol Acetate
A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
Coenzymes
Small molecules that are required for the catalytic function of ENZYMES. Many VITAMINS are coenzymes.
Erythropoiesis
The production of red blood cells (ERYTHROCYTES). In humans, erythrocytes are produced by the YOLK SAC in the first trimester; by the liver in the second trimester; by the BONE MARROW in the third trimester and after birth. In normal individuals, the erythrocyte count in the peripheral blood remains relatively constant implying a balance between the rate of erythrocyte production and rate of destruction.
Diamines
Organic chemicals which have two amino groups in an aliphatic chain.
Hair Cells, Ampulla
Sensory cells in the ampullary crest of each of the semicircular ducts, with their apical STEREOCILIA embedded in a wedge-shaped gelatinous cupula. These hair cells sense the movement of ENDOLYMPH resulting from angular acceleration of the head, and send signals via the VESTIBULAR NERVE to the brain to maintain balance.
Globins
A superfamily of proteins containing the globin fold which is composed of 6-8 alpha helices arranged in a characterstic HEME enclosing structure.
Water
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Granulocytes
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
Metalloproteins
Proteins that have one or more tightly bound metal ions forming part of their structure. (Dorland, 28th ed)
16,16-Dimethylprostaglandin E2
A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.
Tungsten
Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. It is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
Acetone
A colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.
Ethylene Glycols
An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.
Pterins
Compounds based on 2-amino-4-hydroxypteridine.
Dose-Response Relationship, Drug
The relationship between the dose of an administered drug and the response of the organism to the drug.
Hemin
Chloro(7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N(21),N(22),N(23),N(24)) ferrate(2-) dihydrogen.
Shewanella
A genus of gram-negative, facultatively anaerobic rods. It is a saprophytic, marine organism which is often isolated from spoiling fish.
Geotrichosis
Infection due to the fungus Geotrichum.
Free Radical Scavengers
Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
Hydrogen Peroxide
A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
Cell Division
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Electron Spin Resonance Spectroscopy
A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING.

Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells. (1/2132)

CTCF is a transcriptional repressor of the c-myc gene. Although CTCF has been characterized in some detail, there is very little information about the regulation of CTCF activity. Therefore we investigated CTCF expression and phosphorylation during induced differentiation of human myeloid leukemia cells. We found that: (i) both CTCF mRNA and protein are down-regulated during terminal differentiation in most cell lines tested; (ii) CTCF down-regulation is retarded and less pronounced than that of c-myc; (iii) CTCF protein is differentially phosphorylated and the phosphorylation profiles depend on the differentiation pathway. We concluded that CTCF expression and activity is controlled at transcriptional and post-transcriptional levels.  (+info)

Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide. (2/2132)

Epithelial cells from non-cancerous mammary tissue in response to exposure to chemical carcinogens or transfection with oncogenes exhibit hyperproliferation and hyperplasia prior to the development of cancer. Aberrant proliferation may, therefore, represent a modifiable early occurring preneoplastic event that is susceptible to chemoprevention of carcinogenesis. The synthetic retinoid N-(4-hydroxyphenyl)retinamide (HPR), has exhibited preventive efficacy in several in vitro and in vivo breast cancer models, and represents a promising chemopreventive compound for clinical trials. Clinically relevant biochemical and cellular mechanisms responsible for the chemopreventive effects of HPR, however, are not fully understood. Experiments were performed on preneoplastic human mammary epithelial 184-B5/HER cells derived from reduction mammoplasty and initiated for tumorigenic transformation by overexpression of HER-2/neu oncogene, to examine whether HPR inhibits aberrant proliferation of these cells and to identify the possible mechanism(s) responsible for the inhibitory effects of HPR. Continuous 7-day treatment with HPR produced a dose-dependent, reversible growth inhibition. Long-term (21 day) treatment of 184-B5/HER cells with HPR inhibited anchorage-dependent colony formation by approximately 80% (P < 0.01) relative to that observed in the solvent control. A 24 h treatment with cytostatic 400 nM HPR produced a 25% increase (P = 0.01) in G0/G1 phase, and a 36% decrease (P = 0.01) in S phase of the cell cycle. HPR treatment also induced a 10-fold increase (P = 0.02) in the sub-G0 (apoptotic) peak that was down-regulated in the presence of the antioxidant N-acetyl-L-cysteine. Treatment with HPR resulted in a 30% reduction of cellular immunoreactivity to tyrosine kinase, whereas immunoreactivity to p185HER remained essentially unaltered. HPR exposure resulted in time-dependent increase in cellular metabolism of the retinoid as evidenced by increased formation of the inert metabolite N-(4-methoxyphenyl)-retinamide (MPR) and progressive increase in apoptosis. Thus, HPR-induced inhibition of aberrant proliferation may be caused, in part, by its ability to inhibit HER-2/neu-mediated proliferative signal transduction, retard cell cycle progression and upregulate cellular apoptosis.  (+info)

Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations. (3/2132)

High-dose busulphan-containing chemotherapy regimens have shown high response rates in children with relapsed or refractory neuroblastoma, Ewing's sarcoma and medulloblastoma. However, the anti-tumour activity of busulfan as a single agent remains to be defined, and this was evaluated in athymic mice bearing advanced stage subcutaneous paediatric solid tumour xenografts. Because busulphan is highly insoluble in water, the use of several vehicles for enteral and parenteral administration was first investigated in terms of pharmacokinetics and toxicity. The highest bioavailability was obtained with busulphan in DMSO administered i.p. When busulphan was suspended in carboxymethylcellulose and given orally or i.p., the bioavailability was poor. Then, in the therapeutic experiments, busulphan in DMSO was administered i.p. on days 0 and 4. At the maximum tolerated total dose (50 mg kg(-1)), busulphan induced a significant tumour growth delay, ranging from 12 to 34 days in the three neuroblastomas evaluated and in one out of three medulloblastomas. At a dose level above the maximum tolerated dose, busulphan induced complete and partial tumour regressions. Busulphan was inactive in a peripheral primitive neuroectodermal tumour (PNET) xenograft. When busulphan pharmacokinetics in mice and humans were considered, the estimated systemic exposure at the therapeutically active dose in mice (113 microg h ml(-1)) was close to the mean total systemic exposure in children receiving high-dose busulphan (102.4 microg h ml(-1)). In conclusion, busulphan displayed a significant anti-tumour activity in neuroblastoma and medulloblastoma xenografts at plasma drug concentrations which can be achieved clinically in children receiving high-dose busulphan-containing regimens.  (+info)

Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. (4/2132)

Conjugated linoleic acid (CLA; 18:2) is a group of isomers (mainly 9-cis, 11-trans and 10-trans, 12-cis) of linoleic acid. CLA is the product of rumen fermentation and can be found in the milk and muscle of ruminants. Animals fed CLA have a lower body fat content. The objective of this study was to establish the possible mechanisms by which CLA affects adipogenesis. 3T3-L1 is a well-established cell line that is used extensively in studying adipocyte biology. These cells typically grow in a culture medium until they reach confluence, at which time they are induced to differentiate by hormonal treatment (d 0). Treatment of 3T3-L1 cells with 25 to 100 micromol/L CLA inhibited differentiation in a dose-dependent manner, while linoleic acid treatment did not differ from DMSO-treated controls. Continuous treatment from d -2, -1, 0 or 2 to d 8 and treatment from d -2 to d 0 and from d 0 to d 2 inhibited differentiation. Differentiation was monitored morphologically (oil Red-O staining), enzymatically (reduction of activity of glycerol-3-phosphate dehydrogenase), and by northern analysis of peroxisome proliferator-activated receptor gamma2, CCAAT/enhancer binding protein alpha and adipocyte specific protein 2 mRNA. CLA inhibited cell proliferation of nonconfluent cells but did not affect cell division of confluent cells, as indicated by 5-bromo-2'-deoxyuridine incorporation and mitochondria metabolism. Therefore, CLA inhibited differentiation before confluence and during induction. However, cellular proliferation was only inhibited prior to induction. These results imply that fat reduction caused by CLA treatment may be attributed to its inhibition of both proliferation and differentiation of preadipocytes in animals.  (+info)

Flow cytometric cell cycle analysis of cultured porcine fetal fibroblast cells. (5/2132)

Normal development of nuclear transfer embryos is thought to be dependent on transferral of nuclei in G0 or G1 phases of the cell cycle. Therefore, we investigated the cell cycle characteristics of porcine fetal fibroblast cells cultured under a variety of cell cycle-arresting treatments. This was achieved by using flow cytometry to simultaneously measure cellular DNA and protein content, enabling the calculation of percentages of cells in G0, G1, S, and G2+M phases of the cell cycle. Cultures that were serum starved for 5 days contained higher (p < 0.05) percentages of G0+G1 (87.5 +/- 0. 7) and G0 cells alone (48.3 +/- 9.7) compared with rapidly cycling cultures (G0+G1: 74.1 +/- 3.0; G0: 2.8 +/- 1.2). Growth to confluency increased (p < 0.05) G0+G1 percentages (85.1 +/- 2.8) but did not increase G0 percentages (6.0 +/- 5.3) compared to those in cycling cultures. Separate assessment of small-, medium-, and large-sized cells showed that as the cell size decreased from large to small, percentages of cells in G0+G1 and G0 alone increased (p < 0.05). We found 95.2 +/- 0.3% and 72.2 +/- 12.0% of small serum-starved cells in G0+G1 and G0 alone, respectively. Cultures were also treated with cell cycle inhibitors. Treatment with dimethyl sulfoxide (1%) or colchicine (0.5 microM) increased percentages of cells in G0 (24.8 +/- 20.0) or G2+M (37.4 +/- 4.6), respectively. However, cells were only slightly responsive to mimosine treatment. A more complete understanding of the cell cycle of donor cells should lead to improvements in the efficiency of nuclear transfer procedures.  (+info)

In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin. (6/2132)

The effects of NAMI-A (imidazolium trans-imidazoledimethyl sulfoxide-tetrachlororuthenate) are compared with cisplatin on tumor cells cultured in vitro at doses of 1 to 100 microM and on tumor metastases in vivo at maximum tolerated doses. Using mouse tumors that metastasize to the lungs, NAMI-A given i.p. for 6 consecutive days at 35 mg/kg/day, was effective independently of the tumor line being treated and of the stage of metastasis growth. Conversely, cisplatin (2 mg/kg/day for 6 days) was as effective as NAMI-A on MCa mammary carcinoma and TS/A adenocarcinoma and less effective than NAMI-A on Lewis lung carcinoma. Cisplatin reduced body weight gain and spleen weight during treatment and was much more toxic than NAMI-A on liver sinusoids, kidney tubules, and lung epithelium. In vitro NAMI-A caused a transient cell cycle arrest of tumor cells in the premitotic G2/M phase, whereas cisplatin caused a progressive dose-dependent disruption of cell cycle phases. Correspondingly, NAMI-A did not modify cell growth, whereas cisplatin caused a dose-dependent reduction of cell proliferation, as determined by sulforhodamine B test. Thus, NAMI-A, unlike cisplatin, is a potent agent for the treatment of solid tumor metastases as well as when these tumor lesions are in an advanced stage of growth. NAMI-A is endowed with a mechanism of action unrelated to direct tumor cell cytotoxicity, and such mechanism of action is responsible for a reduced host toxicity.  (+info)

Stable thiobarbituric acid chromophore with dimethyl sulphoxide. Application to sialic acid assay in analytical de-O-acetylation. (7/2132)

With dimethyl sulphoxide instead of butanol in the thiobarbituric acid assay for sialic acid, a non-fading chromophore with lambdamax. = 549 nm was produced in a homogeneous solution, allowing dilution of the test mixture in case of high colour yield. This test adapted well to studies on alkaline de-O-acetylation. Bovine and rat submaxillary mucins, and rabbit Tamm-Horsfall urinary sialoproteins contain O-acetyl isomers of neuramine acid that are resistant to the thiobarbituric acid assay. Alkaline de-O-acetylation converted resistant O-acetylneuraminic acid into thiobarbituric acid-reactive sialic acid, and such conversion paralleled de-O-acetylation as measured by the ferric hydroxamate method. The colour increment was similar when the alkaline treatment of bovine submaxillary mucin either preceded or followed the acid hydrolysis. Only alkaline preptreatment was effective with rat submaxillary mucin. By selecting optimal conditions for alkaline de-O-acetylation, O-acetyl isomers can be accurately assessed by the thiobarbituric acid assay.  (+info)

Regulation of IL-8RA (CXCR1) expression in polymorphonuclear leukocytes by hypoxia/reoxygenation. (8/2132)

Interleukin-8 (IL-8) is an important mediator of neutrophil (PMN) function and the type A IL-8 receptor (IL-8RA) mediates these pro-inflammatory signals. Hypoxia or hypoxia/reoxygenation (H/R) affects the production of IL-8, but no data is available regarding its effect on IL-8RA expression. The purpose of this study was to determine the effects of hypoxia and/or H/R on the expression of IL-8RA in PMN. We demonstrated that IL-8RA mRNA levels were similar under normoxic and hypoxic conditions but H/R resulted in a significant reduction in mRNA expression between 30 and 60 min. IL-8RA protein also decreased with reoxygenation of whole blood, which was altered by the addition of specific antioxidants. Therefore, H/R appears to attenuate the effect of IL-8 by down-regulating IL-8RA in PMN. These data show that changes in oxygen tension within the wound site not only affect the expression of inflammatory cytokines, but also control their actions by regulating their receptors.  (+info)

Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion model - Fingerprint -...Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion model - Fingerprint -...
Fingerprint Dive into the research topics of Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion model. Together they form a unique fingerprint. ...
https://scholars.uthscsa.edu/en/publications/effects-of-intravenous-dimethyl-sulfoxide-on-ischemia-evolution-i/fingerprints/
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Nrf2 Contributes to DMSO-induced Erythroid Differentiation in MEL Mouse Erythroleukemia Cells by Regulating EZH2 Expression--...Nrf2 Contributes to DMSO-induced Erythroid Differentiation in MEL Mouse Erythroleukemia Cells by Regulating EZH2 Expression--...
Objective To explore the role of Nrf2/EZH2 in mediating erythroid differentiation in mouse erythroleukemia cells under DMSO exposure. Methods MEL cells were treated with DMSO. Erythroid differentiation was detected by bezidine staining. The expression levels of Nrf2 and EZH2 were determined by western blotting. Results DMSO induced erythroid differentiation in MEL cells,along with significant induction of Nrf2 and EZH2 expression. TBHQ,a selective Nrf2 activator,increased the protein level of Nrf2.Interestingly,TBHQ also induced EZH2 expression. The lentiviral particle containing Nrf2 short hairpin RNA( shRNA) efficiently blocked TBHQ-induced EZH2 levels. Moreover,Nrf2 or EZH2 shRNA significantly inhibited DMSO-induced erythroid differentiation. Conclusion Nrf2 induction is involved in MELerythroid differentiation under DMSO exposure by regulating EZH2.
http://en.cnki.com.cn/Article_en/CJFDTotal-BJMY201711025.htm
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Rabbits treated for 13 weeks with large doses of known dimethyl sulfoxide metabolites did not develop the lenticular changes associated with dimethyl sulfoxide treatment. No hydration of the lens or other tissues could be detected in animals treated p.o. with dimethyl sulfoxide for 24 weeks. Dimethyl sulfoxide was shown to react with glutathione as well as eye lens proteins to yield dimethyl sulfide. A mechanism for dimethyl sulfoxide toxicity to the rabbit lens is postulated.. ...
https://jpet.aspetjournals.org/content/177/3/528
Dimethyl sulfoxide | 67-68-5Dimethyl sulfoxide | 67-68-5
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MSM Dimethylsulfone. Methylsulfonylmethane. Organic sulfur. MSM Dimetylosulfon. Metylosulfonylometan. Siarka organiczna 3kg -...MSM Dimethylsulfone. Methylsulfonylmethane. Organic sulfur. MSM Dimetylosulfon. Metylosulfonylometan. Siarka organiczna 3kg -...
DMSO dimethyl sulfoxide Dimethyl sulfoxide (DMSO, dimethyl sulfoxide), (CH3) 2SO is an organic chemical compound that belongs to the group of sulfoxides. It is used as a chemical reagent and solvent. DMSO is most commonly used in the form of a liquid aqueous solution with a concentration of 70-90% - usually externally, or in gels of various concentrations. Species: clean Specification Name: Dimethylsulfoxide Synonyms: DMSO, dimethyl sulfoxide, dimethyl sulfoxide, methylsulfoxide, methylsulfinylmethane, Genre: Clean Cleanliness: Clean min. 99.9% Chemical formula: (CH3) 2SO. Learn More ...
https://www.sklep.biomus.eu/gb/msm-methylsulfonylmethane-organic-sulfur/628-dimetylosulfon-msm-100g-5902409415582.html
Methylsulfonylmethane Review
Methylsulfonylmethane has a recommended dosage of 3,000mg. Do NOT buy until you read this REAL Methylsulfonylmethane Review. Methylsulfonylmethane...
https://reviews.trackmystack.com/supplements-Methylsulfonylmethane
April 2015 ~ Valley OBGYNApril 2015 ~ Valley OBGYN
During a bladder instillation, also called a bladder wash or bath, the bladder is filled with a solution that is held for varying periods of time, averaging 10 to 15 minutes, before being emptied. The only drug approved by the U.S. Food and Drug Administration (FDA) for bladder instillation is Dimethyl Sulfoxide (DMSO, RIMSO-50). DMSO treatment involves guiding a narrow tube called a catheter up the urethra into the bladder. A measured amount of DMSO is passed through the catheter into the bladder, where it is retained for about 15 minutes before being expelled. Treatments are given every week or two for 6 to 8 weeks and repeated as needed. Most people who respond to DMSO notice improvement 3 or 4 weeks after the first 6- to 8-week cycle of treatments. Highly motivated patients who are willing to catheterize themselves may, after consultation with their doctor, be able to have DMSO treatments at home. Self-administration is less expensive and more convenient than going to the doctors office. ...
https://valleyob.blogspot.com/2015/04/
Polysomal and nonpolysomal messenger RNA of noninduced and induced Friend erythroleukemic cells: analysis by cell-free...
Polyadenylated and nonpolyadenylated mRNA were prepared from polysomes and from the postribosomal supernatant of noninduced and DMSO-induced Friend cells. The mRNA preparations were translated in a wheat germ cell-free system and the in vitro synthesized proteins, fractionated by polyacrylamide gel electrophoresis, were compared by fluorography. The electrophoretic analysis shows that four preparations of poly (A) + RNA code for many different peptides and that most of these peptides are present in each of the poly (A) + RNA translation products. However, the electrophoretic patterns of these translation products differ in the relative amounts of peptides comigrating in the gel electrophoresis. After DMSO treatment, Friend cells show significative differences in the polysomal and nonpolysomal mRNA pools. With induction, globin becomes the most abundant product of the polysomal poly (A) + RNA, while the relative amounts of peptides coded by nonglobin polysomal poly (A) + RNA are reduced. In ...
https://www.meta.org/papers/polysomal-and-nonpolysomal-messenger-rna-of/6948732
DMSO Chemically Alters Cell Membranes to Slow Exocytosis and Increase the Fraction of Partial Transmitter ReleasedDMSO Chemically Alters Cell Membranes to Slow Exocytosis and Increase the Fraction of Partial Transmitter Released
Dimethyl sulfoxide (DMSO) is frequently used as a solvent in biological studies and as a vehicle for drug therapy; but the side effects of DMSO, especially on the cell environment, are not well understood, and controls with DMSO are not neutral at higher concentrations. Herein, electrochemical measurement techniques are applied to show that DMSO increases exocytotic neurotransmitter release, while leaving vesicular contents unchanged. In addition, the kinetics of release from DMSO-treated cells are faster than that of untreated ones. The results suggest that DMSO has a significant influence on the chemistry of the cell membrane, leading to alteration of exocytosis. A speculative chemical mechanism of the effect on the fusion pore during exocytosis is presented.
http://publications.lib.chalmers.se/publication/252799-dmso-chemically-alters-cell-membranes-to-slow-exocytosis-and-increase-the-fraction-of-partial-transm
Indian Patents. 250374:A GENE SIGNATURE FOR MONITORING CANCER PATIENTS TREATED WITH A COMBINATION OF GEMCITABINE AND P276-00
Panc-1 cells were seeded at a density of 2000 cells/well, in a 200 uL in tissue culture grade 96 well plate and allowed to recover for 24 hrs in a humidified 5% ± 0.2 CO2 incubator at 37 °C ± 0.5 °C. After 24 hrs, 1 uL of 200 X (200 times higher than required concentration is denoted as 200 X) compound (dissolved in neat DMSO), as per Table 1 and 2 was added to the wells. The final DMSO concentration was 0.5% in wells. The plate was incubated for 24hrs in humidified 5% + 0.2 CO2 incubator at 37 ± 0.5 °C. After 24 hrs the Minimum Essential Medium (MEM) from the Gemcitabine treated wells was removed and washed two times with fresh MEM and followed by addition of 200 uL of fresh MEM per well. 1 uL of 200 X (200 times higher than required concentration is denoted as 200 X) compound (dissolved in neat DMSO) was then added as per the Table 1 and 2 designs. The final DMSO concentration was 0.5% in wells which also served as the vehicle control for the study. After 72 hrs the plate was removed ...
https://www.allindianpatents.com/patents/250374-a-gene-signature-for-monitoring-cancer-patients-treated-with-a-combination-of-gemcitabine-and-p276-00
The fragmented and condensed nuclei are indicated with arrows, scale bar=20 m - UCHL1 inhibitor or siRNA downregulates the...The fragmented and condensed nuclei are indicated with arrows, scale bar=20 m - UCHL1 inhibitor or siRNA downregulates the...
Tianeptine 100 g/mL streptomycin at 37 C in 5% CO2. Cells had been treated with several concentrations of TBMS1 dissolved in dimethyl sulfoxide (DMSO) with your final DMSO focus of 0.5%. DMSO-treated cells had been used being a control. Cell viability evaluation Cell viability was dependant on the MTT assay as defined previously21. Quickly, DU145 Rabbit Polyclonal to Mnk1 (phospho-Thr385) and Computer3 cells had been seeded in 96-well tissues lifestyle plates and incubated within a CO2 incubator for 24 h, as well as the cells had been then subjected to different concentrations of TBMS1 (1C100 mol/L) for 24 h. Pursuing treatment, 10 L MTT reagent (5 mg/mL) was put into each well, and cells were incubated at 37 C for 4 h additional. Subsequently, 150 L DMSO was put into dissolve the formazan crystals, and absorbance was assessed at 570 nm within a microplate audience (Thermo Scientific, Varioskan Display, USA). The percentage cell viability was computed the following: The IC50 worth was computed ...
https://lxsustentavel.com/%EF%BB%BFthe-fragmented-and-condensed-nuclei-are-indicated-with-arrows-scale-bar20-m/
Plus itPlus it
Early membrane events in erythroid differentiation were investigated by means of cell electrophoresis utilizing cultured Friend erythroleukemia cell clones of different inducibility. The cell electrophoretic mobility decreased by 18% within 30 min of treatment with 1.5% dimethyl sulfoxide (DMSO) in highly inducible clones but not in noninducible clones. The reduced mobility persisted for 5 days of incubation with DMSO until hemoglobin synthesis. DMSO treatment for less than 16 hr and subsequent incubation without the drug resulted in the complete recovery of the mobility and no hemoglobin synthesis. Longer exposure to DMSO resulted in the loss of recovery of mobility and an increasing fraction of benzidine-positive cells seen on Day 5. Measurement of the electrophoretic mobility after the removal of acidic sugars by their specific enzymes suggested that hyaluronidase-sensitive negative charges were lost from the cell surface only in highly inducible clones. The mobility reduction associated with ...
http://cancerres.aacrjournals.org/content/39/3/1113
Chondroitin, glucosamine, and methylsulfonylmethane Uses, Side Effects & Warnings - Drugs.comChondroitin, glucosamine, and methylsulfonylmethane Uses, Side Effects & Warnings - Drugs.com
Physician reviewed chondroitin, glucosamine, and methylsulfonylmethane (MSM) patient information - includes chondroitin, glucosamine, and methylsulfonylmethane description, dosage and directions.
https://www.drugs.com/mtm/chondroitin-glucosamine-and-methylsulfonylmethane-msm.html
aisahiskar: Review NaturVet 240 Count Glucosamine DS with Methylsulfonylmethane Tablets for Dogsaisahiskar: Review NaturVet 240 Count Glucosamine DS with Methylsulfonylmethane Tablets for Dogs
In general as far as I know customers who bought NaturVet 240 Count Glucosamine DS with Methylsulfonylmethane Tablets for Dogs or other products in the Internet also were interested in reviews, cheap & lowest prices in outlets and stores, shipping, gift ideas, city deals, sales, coupons online, new, holiday & daily deals, bargain, best buy products including special offers on NaturVet 240 Count Glucosamine DS with Methylsulfonylmethane Tablets for Dogs, best deals, discount coupons, top & hot deals, great offers, last minute deals and so on ...
http://aisahiskar.blogspot.com/2014/02/review-naturvet-240-count-glucosamine.html
Towards enhancing the durability and strength of dentin-resin bond : the role of dimethyl sulfoxide (DMSO) as an alternative...
UTUShop » Kirjat ja julkaisut » Annales Universitatis Turkuensis » Towards enhancing the durability and strength of dentin-resin bond : the role of dimethyl sulfoxide (DMSO) as an alternative solvent in dental adhesives ...
https://utushop.utu.fi/p/3011-towards-enhancing-the-durability-and-strength-of-dentin-resin-bond-the-role-of-dimethyl-sulfoxide-dmso-as-an-alternative-solvent-in-dental-adhesives/
Cbd مع dmso
Transition Metal Complexes of Dimethyl Sulfoxide: The Preparation of Cu(DMSO) 2 Cl 2 and Ru(DMSO) 4 Cl 2 Introduction. The nature of dimethyl sulfoxide (DMSO, (CH 3) 2 SO) as a monodentate ligand is explored in this set of experiments. 1,2 DMSO can ligate metal atoms by bonding in one of two possible ways: through the oxygen atom or through the sulfur atom (Figure 1). DMSO, Dimethyl Sulfoxide, GC Headspace Grade, Fisher DMSO processed to high purity for accurate and repeatable determination of trace levels of residual solvents. Every lot is tested to ensure interference free baselines for interference free determination of Class 1, 2, and 3 residual solvents; 1 ppm max. of Class 1 Solvents, 10 ppm max. of Class 2 solvents, and 50 ppm max of Class 3 residual DMSO? - HealingWell.com Sep 09, 2014 · I heard about DMSO from Levi here posting about how one of the immediate effects was a firming of the stool and pain relief, and will be trying to reproduce these results at home. I purchased the 99.98% ...
https://cbdusajsp.web.app/cazoq/cbd-dmso168.html
Antitrypanosomal Activities of Proteasome Inhibitors | Antimicrobial Agents and ChemotherapyAntitrypanosomal Activities of Proteasome Inhibitors | Antimicrobial Agents and Chemotherapy
Bloodstream form T. brucei (TC221) and human myeloid leukemia HL-60 cells were grown axenically as described previously (11).. For toxicity tests, cells were seeded into 24-well plates at appropriate densities (104 trypanosomes/ml; 5 × 104 HL-60 cells/ml) in 1 ml of medium containing various concentrations (10−4 to 10−12 M) of proteasome inhibitors dissolved in 100% dimethyl sulfoxide (DMSO). The controls contained DMSO alone. In all experiments, the final DMSO concentration was 1%, which had no effect on the cell growth (11). After 48 h of incubation, living cells were counted with a Neubauer hemocytometer. The control cell counts were 106 trypanosomes/ml and 5 × 105 HL-60 cells/ml. Each experiment was set up in duplicate and repeated three times.. For detection of apoptosis, cells were exposed to proteasome inhibitors at various concentrations for 24 h, harvested by centrifugation, and fixed overnight with 70% ethanol at −20°C. Then, cells were washed twice with HBSS (Hanks balanced ...
https://aac.asm.org/content/46/6/2038
Dimethyl Sulfoxide - DMSO | EquiMed - Horse Health MattersDimethyl Sulfoxide - DMSO | EquiMed - Horse Health Matters
Learn why Dimethyl sulfoxide is used for emergency treatment of brain and spinal cord inflammation, endotoxemia, laminitas, and in the treatment of very sick, young foals.
https://equimed.com/drugs-and-medications/reference/dimethyl-sulfoxide-dmso
Decomposition of alpha-Chloro-Oximes in Dimethyl Sulphoxide,
The function of dimethyl sulfoxide (DMSO) as both an electrophilic and nucleophilic reagent has been well established. However, its reactions with substrates which are similarly biphilic have attracted little comment, even though they are of potential mechanistic and preparative interest. Discussed are the mechanisms involved in the heating of alpha-chloro-p-nitrobenzaldoxime in DMSO. (Author)(*OXIMES
http://oai.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=AD0738768
MAP kinase upregulation after hematopoietic differentiation: role of chemotaxis. - Semantic ScholarMAP kinase upregulation after hematopoietic differentiation: role of chemotaxis. - Semantic Scholar
Mitogen-activated protein kinase (MAPK) isoform p42 is known to be active in exponentially growing cells at several points of the cell cycle. A high basal activity was present in three cell lines representative of immature myeloid cells tested: uHL-60, AML-14, and MPD. However, DMSO-induced differentiation of HL-60 cells (dHL-60) and subsequent expression of the neutrophilic phenotype occurred with a concomitant reduction on the basal level of MAPK activity. Simultaneously, extracellular stimuli like the cytokine granulocyte/macrophage colony-stimulating factor (GM-CSF) induced a fast (|10 min) and robust response. In terms of MAPK activity, the more mature the cell was, the higher the corresponding activity, in the three differentiation series considered: AML-14 | 3D10; MPD | G-MPD; uHL-60 | dHL-60 | neutrophils. Interestingly, peripheral blood neutrophils expressed the highest (16-fold) MAPK activation level in response to GM-CSF. Finally, using the specific MAPK inhibitor PD-98059, we demonstrated
https://www.semanticscholar.org/paper/MAP-kinase-upregulation-after-hematopoietic-differ-Lehman-Paul/6b9895c6c63280ca4b173ba5257bf5057ef25471
September | 2014 | Liver X receptor
Cell growth inhibition assay and data analysis Cells were plated at appropriate density in 96 very well plates such they would remain in log growth with the finish of assay time. The cells had been allowed to attach overnight before getting exposed to Mek inhibitor CI 1040, UO126 or GSK1120212 for 72 h. Medication have been dissolved in dimethyl sulfoxide as 10 mM stock, and a set of 9 doses in 1,5 serial dilution was added in tripli cate wells. The last DMSO concentration from the taken care of well was 0. 3% or much less. The cell development was established utilizing Cell Titer Glo assay, with slight modification from the producers protocol at day 0 and day 3 of drug publicity. Briefly, Cell Titer Glo reagent was diluted with phosphate buffered saline as well as culture media was eliminated in the 96 well plate prior to including 50 ?l per well from the diluted Cell Titer Glo rea gent.. Luminescence in the assay was recorded making use of BIO TEK FLx800. Data calculations were manufactured in ...
https://liverxreceptor.com/2014/09
DIMETHYL SULFOXIDE - CAS - 67-68-5 (02190186) - MP BiomedicalsDIMETHYL SULFOXIDE - CAS - 67-68-5 (02190186) - MP Biomedicals
Dimethyl sulfoxide is used to enhance dermal absorption of many chemicals.A solvent for many organic and inorganic compounds including fats, carbohydrates, dyes, resins, and polymers.Used in antifreeze or hydraulic fluids and as a cryopreservative for cell cultures.Used in the oxidation of thiols and disulfides to sulfonic acids. Used as a PCR cosolvent to help improve yields, especially in long PCR. ...
https://www.mpbio.com/product.php?pid=02190186&country=223
SPECTRUM Dimethyl Sulfoxide,100mL,CAS 67-68-5 - 46AJ70|D1388-100ML - GraingerSPECTRUM Dimethyl Sulfoxide,100mL,CAS 67-68-5 - 46AJ70|D1388-100ML - Grainger
Looking for SPECTRUM Dimethyl Sulfoxide,100mL,CAS 67-68-5 (46AJ70)? Graingers got your back. Price:$154.50. Easy ordering & convenient delivery. Log-in or register for your pricing.
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The dependence of erythroid differentiation on cell replication in dim by A W. Wiens, P R. Clintock et al.The dependence of erythroid differentiation on cell replication in dim by A W. Wiens, P R. Clintock et al.
Wiens, A W.; Clintock, P R.; and Papaconstantinou, J, The dependence of erythroid differentiation on cell replication in dimethyl sulfoxide-treated friend leukemia- -virus-infected cells. (1976). Subject Strain Bibliography 1976. 2169 ...
https://mouseion.jax.org/ssbb1976/2169/
Source Naturals - Source Naturals - MSM (Methylsulfonylmethane) 750 mg - 60 tabs
MSM (Methylsulfonylmethane) 750 mg - 60 tabletsRecommended Use:2 to 4 tablets daily, or as recommended by your health care professional.MSM serves as an important source of bioavailable dietary sulfur, a mineral which plays a critical role in maintaining the integrity and elasticity of connective and other tissues. It is an important component in proteins found throughout the body such as in hair, nails, skin and tendons. Vitamin C helps support connective tissue, amino acid metabolism, hormone synthesis and is a key factor in the bodys natural defenses. MSM is a naturally occurring form of organic sulfur found mainly in protein-rich foods such as eggs, fish and lean meat. Taking MSM throughout the day helps to replenish the bodys supply of assimilable sulfur.Ingredients:WARNING: Keep out of the reach of children. Do not use if either tamper-evident seal is broken or missing. Store in a cool, dry place. Not for use by pregnant or nursing women.
http://www.totaldiscountvitamins.com/product/12883/source_naturals
Where to buy MSM Sulphur (Methylsulfonylmethane) for Joint Pain in Singapore? Vitadeals online health supplement store | Online...Where to buy MSM Sulphur (Methylsulfonylmethane) for Joint Pain in Singapore? Vitadeals online health supplement store | Online...
Methylsulfonylmethane, better known as MSM, is a rich source of dietary sulphur, and is a vital aid in reducing joint pain and arthritis symptoms. It is anti-inflammatory and helps recovery after exercise. Available in Singapore from Vitadeals.
https://vitadeals.sg/anti-inflammatory.html/piping-rock-msm-sulfur-1.html
St. Francis MSM (Methylsulfonylmethane) in Canada from $22.99 | Free Shipping over $49St. Francis MSM (Methylsulfonylmethane) in Canada from $22.99 | Free Shipping over $49
St. Francis MSM (Methylsulfonylmethane) is a natural anti-inflammatory sulfur compound thats great for arthritis, as well as being an immune system modulator.
https://www.vitamart.ca/st.-francis-msm-methylsulfonylmethane.html
MSM, Methylsulfonylmethane (90 tabs)MSM, Methylsulfonylmethane (90 tabs)
MSM, Methylsulfonylmethane, from Nature\s Sunshine Products traditionally used to support the structural and circulatory systems, connective tissue and healthy joints.
http://www.choosenaturalhealth.net/product/4059
Pure Organic Ingredients Methylsulfonylmethane Msm Powder 100% Pure And May Increase Joint & Connective Tissue Health...Pure Organic Ingredients Methylsulfonylmethane Msm Powder 100% Pure And May Increase Joint & Connective Tissue Health...
Pure Organic Ingredients Methylsulfonylmethane Msm Powder 100% Pure And May Increase Joint & Connective Tissue Health Respiratory & Digestive System | Reviews Online | PriceCheck
https://www.pricecheck.co.za/offers/168200892/Pure+Organic+Ingredients+Methylsulfonylmethane+Msm+Powder+100%25+Pure+And+May+Increase+Joint+%26+Connective+Tissue+Health+Respirator
Chondroitin/Glucosamine/Methylsulfonylmethane Support Group - Drugs.comChondroitin/Glucosamine/Methylsulfonylmethane Support Group - Drugs.com
Ask questions and get answers about Chondroitin/Glucosamine/Methylsulfonylmethane. Our support group helps people share their own experience. 10 news articles.
https://www.drugs.com/answers/support-group/chondroitin-glucosamine-methylsulfonylmethane/
What Are the Dangers of Methylsulfonylmethane? | Livestrong.comWhat Are the Dangers of Methylsulfonylmethane? | Livestrong.com
The supplement methylsulfonylmethane, sometimes called MSM, is a sulfur compound promoted as useful for health conditions involving pain and inflammation.
https://www.livestrong.com/article/506314-what-are-the-dangers-of-methylsulfonylmethane/
MMP9 and MMP2 Substrate (Fluorogenic) - PEPDAB011
Use:. This mmp substrate can be used to assess activity of MMP9 and MMP2. This mmp substrate has been used in enzymatic and cell based assays to assess activity of MMP9 and MMP2 since it is specific for this family of metalloproteinases. See our Product Sheets for its substrate specificity profile. Typically, the peptide is dissolved in DMSO to make a stock solution of about 10uM concentration. When used for in vitro assays, the substrate is often used at about 10mM concentration. Remember to keep the DMSO concentration in the final reaction at 1% or below, to avoid DMSO effects on the reaction, and remember to have an equivalent percentage of DMSO in the background wells. For use with the MMPs, the buffer should contain 50 mM Tris, pH 7.5, 150 mM NaCl, 2 mM CaCl2, 5 µM ZnSO4, and 0.01% Brij-35. Excitation and emission wavelengths are 485 and 530 nm respectively.. Molecular Weight:. 1423.4 g/mol. Purity:. Greater than 95% as assessed by HPLC and Mass Spectrometry.. Solubility:. 1 mg/ml in water ...
http://www.biozyme-inc.com/BioZymeWP/mmp9-and-mmp2-substrate-fluorogenic-pepdab011
MMP Substrate II (Fluorogenic) - PEPDAB061
Use:. This mmp substrate can be used to assess activity of enzymes in the MMP family. The peptide sequence was described originally as a biosensor for MT1-MMP or MMP14 in Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer. Ouyang M, et al. Cancer Res. 2010 Mar 15;70(6):2204-12. doi: 10.1158/0008-5472.CAN-09-3698″. It demonstrates reasonably strong activity against MT1-MMP or MMP14 and MMP3, but has the highest activity against MMP9 with specificity constants, kcat/Km (M-1s-1), ranging from approximately 103 to 106. See also our Product Sheets for its substrate specificity profile. This substrate is not processed by ADAM family members. Typically, the peptide is dissolved in DMSO to make a stock solution of about 10mM concentration. When used for in vitro assays, the substrate is often used at about 10uM concentration. Remember to keep the DMSO concentration in the final reaction at 1% or below, to avoid DMSO effects on the ...
http://www.biozyme-inc.com/BioZymeWP/mmp-substrate-ii-fluorogenic-pepdab061
Dimethyl SulphoxideDimethyl Sulphoxide
My first day using DMSO was a complete success. DMSO stings like sunburn at 100% dilution. It also turns the skin red just like sunburn. But that only lasts about 20 minutes. It gets itchy, prickly & stings. Then the stuff soaks into the skin - you dont rub it.. After 10 minutes the analgesic property is pretty much 100%. I could feel zero pain in my shoulder that has hurt for 11 weeks. I could even stretch in positions that would have dropped me to the floor in agony an hour earlier.. This analgesia lasts for 3-5 hours and is very pronounced. Yesterday I had the best workout I have had in 11 weeks - it was great.. You do need to be careful because there is such great pain reduction you dont want to forget you have an injury. The smell is there but not sickening to the user. I dont know how it would smell to another person. Probably quite bad.. As for the anti inflammatory effect it will take a couple of weeks to kick in I expect.. With DMSO you must be very careful not to contaminate it with ...
http://www.freefitnessguru.com/blog/tag/dimethyl-sulphoxide
Cytokines Induced by a Toll-Like Receptor 7 Agonist Potently Inhibit HBV RNA, DNA, and Antigen Levels in Primary Human...Cytokines Induced by a Toll-Like Receptor 7 Agonist Potently Inhibit HBV RNA, DNA, and Antigen Levels in Primary Human...
Results: The TLR7 agonist compound A (a close analog of GS-9620), had no direct antiviral activity in HBV-infected PHH, consistent with the lack of functional TLR7 in hepatocytes. In contrast, sustained exposure of HBV-infected PHH to TLR7-CM strongly reduced the levels of HBV DNA and HBeAg (>90%), as well as HBsAg and HBV RNA (>75%), without detectable toxicity. Reductions in viral parameters were observed when PHH were treated with TLR7-CM early (3 days) or late (13 days) post-infection, but were not induced by media from control DMSO-treated PBMCs. We next compared the durability of short (3 day) and long (10 day) treatment of HBV-infected PHH with TLR7-CM. Short duration treatment (days 3-6 post-infection) only transiently reduced HBeAg. In contrast, prolonged treatment (days 3-13 post-infection) induced more sustained suppression of HBeAg, with rebound still incomplete 7 days after removal of TLR7-CM (day 20). A survey of cytokines in TLR7-CM identified recombinant IFN-α2a as a potent ...
http://www.natap.org/2014/AASLD/AASLD_139.htm
AID 780551 - Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of mRNA ratio of bcl2...AID 780551 - Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of mRNA ratio of bcl2...
BioAssay record AID 780551 submitted by ChEMBL: Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of mRNA ratio of bcl2 to bax at 10 uM after 2 days by RT-PCR method relative to DMSO-treated control.
https://pubchem.ncbi.nlm.nih.gov/bioassay/780551
March | 2015 | Alk Pathway
SAHA was bought as being a dry powder and reconstituted in dimethyl sulfoxide at 0. five M and stored at 20C. Proliferation assay Each cell lines have been plated at minimal seed onto a 24 properly plate. This was allowed overnight incubation. The fol lowing day, the media was eliminated and replaced with media containing preset concentrations of valproate or SAHA. These Inhibitors,Modulators,Libraries have been incubated for 72 hrs. At that point, the media was removed and media containing no remedy but supplemented with 10% Alamar blue was extra. This was allowed to incubate for three hours at which stage absorbance was go through at 570 and 600 nm. Each problem had four replicates. The ratio of absorb ance at 570 to 600 nm was scaled from zero for that no cell wells to 100% to the no therapy wells. The data have been analyzed by t test making use of JMP Statistical Application.. Expression evaluation Cells were grown in 25 cm2 T flasks and treated with valproate from 0 mM to 5 mM while SAHA ...
https://alkpathway.com/2015/03/
Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by...Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by...
The |i|Journal of Biomedical Optics|/i| (JBO) is an open access journal that publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.
https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-13/issue-02/021105/Penetration-kinetics-of-dimethyl-sulphoxide-and-glycerol-in-dynamic-optical/10.1117/1.2899153.full?SSO=1
dimethyl sulfone - methylsulfonylmethane Summary Report | CureHunterdimethyl sulfone - methylsulfonylmethane Summary Report | CureHunter
dimethyl sulfone: MSM is abreviation; a normal oxidative metabolite product of dimethyl sulfoxide (DMSO) found in foods; RN given refers to unlabeled cpd;
http://www.curehunter.com/public/keywordSummaryC025910-dimethyl-sulfone-methylsulfonylmethane.do
Benefits of MSM | The Ultimate Health University
The health benefits of MSM are numerous, and as such it has become a very popular natural treatment for arthritis and related ailments.. Methylsulfonylmethane - its quite a mouthful, but MSM, a naturally occurring sulfur compound, can be a safe and effective natural remedy against the inflammation of rheumatoid arthritis, osteoarthritis, fibromyalgia and gout, not to mention allergies. For centuries people have visited hot springs rich in the natural element sulfur to soothe muscle aches and pains, so it makes sense that they would seek out the health benefits of MSM to soothe similar ailments today.. Where exactly does MSM come from? In a nutshell - microscopic plankton release sulfur into the ocean, where the element becomes DMS (dimethyl sulfide.) It is then converted into its relatives DMSO (dimethyl sulfoxide) and MSM. Because, it is soluble in water, MSM eventually makes its way into the root systems of plants. When we include fresh, unprocessed plants in our diet, we reap the health ...
https://theultimatehealthuniversity.com/benefits-of-msm/
DMSO | Define DMSO at Dictionary.comDMSO | Define DMSO at Dictionary.com
DMSO definition, dimethyl sulfoxide: a liquid substance, C 2 H 6 OS, used in industry as a solvent and paint and varnish remover; proposed as an analgesic and anti-inflammatory in musculoskeletal disorders. See more.
http://www.dictionary.com/browse/dmso?qsrc=2446
The Tetraheme Cytochrome CymA Is Required for Anaerobic Respiration with Dimethyl Sulfoxide and Nitrite in Shewanella...The Tetraheme Cytochrome CymA Is Required for Anaerobic Respiration with Dimethyl Sulfoxide and Nitrite in Shewanella...
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https://www.infona.pl/resource/bwmeta1.element.acs-doi-10_1021_bi034456f
Select The Best MSM 4 lbs | Adams Horse SuppliesSelect The Best MSM 4 lbs | Adams Horse Supplies
MSM (Methylsulfonylmethane) is a metabolite of DMSO (dimethyl sulfoxide) found in nature. Found extensively in nature, DMSO has been used as a carrier for various compounds. The strong odor, along with the resultant foul breath and skin irritations that r
https://www.adamshorsesupplies.com/select-the-best-msm-4-lbs-1831185
Dimethyl SulfoxideDimethyl Sulfoxide
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/cbook.cgi?Source=1948DOU2001-2002&Units=SI&Mask=1A8F
佐々木 典康 (Noriyasu Sasaki) - Endothelium-Dependent and -Independent Vasodilator Effects of Dimethyl Sulfoxide in Rat Aorta - 論文 -...佐々木 典康 (Noriyasu Sasaki) - Endothelium-Dependent and -Independent Vasodilator Effects of Dimethyl Sulfoxide in Rat Aorta - 論文 -...
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https://researchmap.jp/read0142879/published_papers/14206349?lang=ja
WHAT DMSO DOES? - ChelationCure
DMSO tends to build up white blood cells and increase immune production of MIF (migration inhibitory factors) of macrophages. Thus, the immune system is made more effective by allowing macrophages to move more quickly. Thus DMSO modulates lymphocytes, and it therefore reactivates the production of MIF. It also diminishes allergic reactions by unfolding the cell membrane and making more cell receptor sites available to attachment by specific antigens.. The modulating effect of DMSO on lymphocytes also tends to increase the production of lymphokines (chemical immune cell mediators) such as interferon. It potentiates cell mediated immunity and can be effective in multiple sclerosis, systemic lupus, erythematosus, rheumatoid arthritis, thyroiditis, ulcerative colitis, cancer, etc.. This is not a drug in the usual sense, since a drug treats disease symptoms. DMSO treats altered cellular function or damaged cells. The cells become healed and restored by changing and stabilizing the water structure ...
https://chelationcure.com/what-dmso-does/
Difference between revisions of YBR033W - SGD-Wiki
The graph above shows the effect of 3% DMSO on YBR033W. From the data represented the average doubling rate for the YBR033W knockout strain without DMSO was 634 minutes. When DMSO is added the average doubling time increased to 1292 minutes. This shows that 3% DMSO did add stress to this knockout strain. The average doubling time of WT:BY4735 without DMSO was 514 minutes. The average doubling rate for WT:BY4735 with DMSO was 1529 minutes. If we compare the average doubling rate of WT:BY4735 with DMSO to YBR033W with DMSO we can see that without the YBR033W gene the yeast was able to grow more quickly under DMSO induced stress. ...
https://wiki.yeastgenome.org/index.php?title=YBR033W&diff=next&oldid=401996
6 Health Benefits of MSM (Methylsulfonylmethane) - ArticleCity.com6 Health Benefits of MSM (Methylsulfonylmethane) - ArticleCity.com
Originally posted on https://www.ageless-nutrition.com/6-health-benefits-of-msm-methylsulfonylmethane/ Although it might be a bit of a mouthful,
https://www.articlecity.com/blog/6-health-benefits-of-msm-methylsulfonylmethane/
Dimethyl sulfoxideDimethyl sulfoxide
... (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is the sulfoxide most ... Dimethyl sulfoxide is produced industrially from dimethyl sulfide, a by-product of the Kraft process, by oxidation with oxygen ... "Dimethyl sulfoxide (DMSO) waste residues and municipal waste water odor by dimethyl sulfide (DMS): the North-East WPCP plant of ... ISBN 3-609-48040-8 Wikimedia Commons has media related to dimethyl sulfoxide. International Chemical Safety Card 0459 Dimethyl ...
https://en.wikipedia.org/wiki/Dimethyl_sulfoxide
Dimethyl sulfoxide (data page)Dimethyl sulfoxide (data page)
monograph 3249 "Dimethyl Sulfoxide (DMSO) -- Technical". Atofina Chemicals, inc. Retrieved 26 May 2007. "Pure Component ... This page provides supplementary chemical data on dimethyl sulfoxide. The handling of this chemical may incur notable safety ...
https://en.wikipedia.org/wiki/Dimethyl_sulfoxide_(data_page)
Dichlorotetrakis(dimethylsulfoxide)ruthenium(II)Dichlorotetrakis(dimethylsulfoxide)ruthenium(II)
Dichlorotetrakis(dimethyl sulfoxide) ruthenium(II) describes coordination compounds with the formula RuCl2(dmso)4, where DMSO ... Enzo Alessio (2004). "Synthesis and reactivity of Ru-, Os-, Rh-, and Ir-halide-sulfoxide compounds". Chem. Rev. 104 (9): 4203- ... B. R. James; E. Ochiai; G.I. Rempel (1971). "Ruthenium (II) halide dimethylsulphoxide complexes from hydrogenation reactions". ... I. Bratsos; E. Alessio (2010). "Ruthenium(II) Chloro Complexes of dimethylsulfoxide". Inorganic Syntheses. 35: 148-152. doi: ...
https://en.wikipedia.org/wiki/Dichlorotetrakis(dimethylsulfoxide)ruthenium(II)
Potomac horse feverPotomac horse fever
... intravenous dimethyl sulfoxide; administration of products such as Biosponge or activated charcoal via nasogastric tube to bind ...
https://en.wikipedia.org/wiki/Potomac_horse_fever
Swern oxidationSwern oxidation
... which will oxidize the dimethyl sulfide back to dimethyl sulfoxide or to dimethyl sulfone, both of which are odourless and ... Tidwell, T. T. (1990). "Oxidation of alcohols by activated dimethyl sulfoxide and related reactions: An update". Synthesis ( ... ISBN 0-387-23607-4. Mancuso, A. J.; Swern, D. (1981). "Activated dimethyl sulfoxide: Useful reagents for synthesis". Synthesis ... Omura, Kanji; Sharma, Ashok K.; Swern, Daniel (1976). "Dimethyl Sulfoxide-Trifluoroacetic Anhydride. New Reagent for Oxidation ...
https://en.wikipedia.org/wiki/Swern_oxidation
Trifluoroacetic anhydrideTrifluoroacetic anhydride
"Dimethyl Sulfoxide-Trifluoroacetic Anhydride. New Reagent for Oxidation of Alcohols to Carbonyls". J. Org. Chem. 41 (6): 957- ... it reduces sulfoxides to sulfides. Trifluoroacetic anhydride is the recommended desiccant for trifluoroacetic acid. Sigma- ...
https://en.wikipedia.org/wiki/Trifluoroacetic_anhydride
CarbanionCarbanion
Bordwell, Frederick G. (1988). "Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): ... "Acidity of Strong Acids in Water and Dimethyl Sulfoxide". The Journal of Physical Chemistry A. 120 (20): 3663-3669. Bibcode: ... These values below are pKa values determined in dimethylsulfoxide (DMSO), which has a broader useful range (~0 to ~35) than ...
https://en.wikipedia.org/wiki/Carbanion
Bordwell thermodynamic cycleBordwell thermodynamic cycle
"Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): 456-463. doi:10.1021/ar00156a004 ...
https://en.wikipedia.org/wiki/Bordwell_thermodynamic_cycle
FluoreneFluorene
F. G. Bordwell (1988). "Equilibrium acidities in dimethyl sulfoxide solution". Acc. Chem. Res. 21 (12): 456-463. doi:10.1021/ ...
https://en.wikipedia.org/wiki/Fluorene
Sulfonic acidSulfonic acid
Bordwell, Frederick G. (1988). "Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): ...
https://en.wikipedia.org/wiki/Sulfonic_acid
MethaneMethane
Bordwell, Frederick G. (1988). "Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): ...
https://en.wikipedia.org/wiki/Methane
IndeneIndene
"Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): 456-463. doi:10.1021/ar00156a004 ...
https://en.wikipedia.org/wiki/Indene
AcetoneAcetone
Bordwell, Frederick G. (1988). "Equilibrium acidities in dimethyl sulfoxide solution". Accounts of Chemical Research. 21 (12): ... Acetone (2-propanone or dimethyl ketone), is an organic compound with the formula (CH3)2CO. It is the simplest and smallest ...
https://en.wikipedia.org/wiki/Acetone
Organobromine compoundOrganobromine compound
Dennis P. Bauer; Roger S. Macomber (1975). "Iodide catalysis of oxidations with dimethyl sulfoxide. Convenient two-step ...
https://en.wikipedia.org/wiki/Organobromine_compound
Diethyl malonateDiethyl malonate
Olmstead, William N.; Bordwell, Frederick G. (1980). "Ion-pair association constants in dimethyl sulfoxide". The Journal of ...
https://en.wikipedia.org/wiki/Diethyl_malonate
Treatment of equine lamenessTreatment of equine lameness
Dimethyl sulfoxide (DMSO) is a chemical solvent. It is used topically to reduce inflammation associated with an acute injury- ... Toxicity of dimethyl sulfoxide, alone and in combination. Ann. NY Acad. Sci. 1975;243:98. Smith, Roger KW. "Mesenchymal stem ... Wood DC, Wood J. Pharmacologic and biochemical considerations of dimethyl sulfoxide. Ann. NY Acad. Sci. 1975;243:7. Gorog P, ... Antiarthritic and antithrombotic effects of topically applied dimethyl sulfoxide. Ann. NY Acad. Sci. 1975;243:91. Rubin LE. ...
https://en.wikipedia.org/wiki/Treatment_of_equine_lameness
Benzoic acidBenzoic acid
Olmstead, William N.; Bordwell, Frederick G. (1980). "Ion-pair association constants in dimethyl sulfoxide". The Journal of ...
https://en.wikipedia.org/wiki/Benzoic_acid
Devon W. MeekDevon W. Meek
"Transition Metal Ion Complexes of Dimethyl Sulfoxide". Journal of the American Chemical Society. 82 (23): 6013-6016. doi: ... His MS and Ph.D. were received at the University of Illinois at Urbana-Champaign, where he studied sulfoxide complexes of ... 7-dimethyl-4,6-octanedione". Inorganic Chemistry. 6 (6): 1105-1110. doi:10.1021/ic50052a009. ISSN 0020-1669. Green, Lisa M.; ...
https://en.wikipedia.org/wiki/Devon_W._Meek
Poly(methyl acrylate)Poly(methyl acrylate)
It is soluble in dimethyl sulfoxide (DMSO). PMA is water-sensitive and unlike PMMA, is not stable against alkalies. It is used ...
https://en.wikipedia.org/wiki/Poly(methyl_acrylate)
Kolbe nitrile synthesisKolbe nitrile synthesis
This type of reaction together with dimethyl sulfoxide as a solvent is a convenient method for the synthesis of nitriles. The ... An Advantageous Nucleophilic Displacement in Dimethyl Sulfoxide". Journal of Organic Chemistry. 25 (6): 877-879. doi:10.1021/ ...
https://en.wikipedia.org/wiki/Kolbe_nitrile_synthesis
MethylsulfonylmethaneMethylsulfonylmethane
Morton JI, Siegel BV (November 1986). "Effects of oral dimethyl sulfoxide and dimethyl sulfone on murine autoimmune ... The spectrum of biological effects of dimethyl sulfoxide (DMSO) and MSM differ, but those of DMSO may be mediated, at least in ... Oxidation of dimethyl sulfoxide produces the sulfone, both under laboratory conditions and metabolically. Because of its ... Kocsis JJ, Harkaway S, Snyder R (January 1975). "Biological effects of the metabolites of dimethyl sulfoxide". Annals of the ...
https://en.wikipedia.org/wiki/Methylsulfonylmethane
Albright-Goldman oxidationAlbright-Goldman oxidation
Dimethyl sulfoxide/acetic anhydride serves as oxidizing agent. The reaction does not proceed further to the carboxylic acid. ... The following figure shows the reaction mechanism: First, dimethyl sulfoxide (1) reacts with acetic anhydride to form a ... 33-36, ISBN 978-0-470-28662-3 J. Donald Albright, Leon Goldman (1967), "Dimethyl sulfoxide-acid anhydride mixtures for the ... The latter reacts upon elimination of acetic acid and dimethyl sulphide to the aldehyde. The Albright-Goldman oxidation is a ...
https://en.wikipedia.org/wiki/Albright–Goldman_oxidation
Sodium methylsulfinylmethylideSodium methylsulfinylmethylide
... and dialkali salts of dimethyl sulfone, dimethyl sulfoxide, and related compounds". J. Organomet. Chem. 59: 53-64. doi:10.1016/ ... "The Dimethyl Sulfoxide (DMSO) Anion - Dimsyl Ion" (PDF). Gaylord Chemical Corporation. October 2007. Archived from the original ... is the sodium salt of the conjugate base of dimethyl sulfoxide. This unusual salt has some uses in organic chemistry as a base ... "One-pot synthesis of β-keto sulfones and β-keto sulfoxides from carboxylic acids". J. Org. Chem. 54 (23): 5620-5623. doi: ...
https://en.wikipedia.org/wiki/Sodium_methylsulfinylmethylide
Shar Pei feverShar Pei fever
Colchicine and dimethyl sulfoxide are most commonly used. Dogs taking colchicine must be monitored closely for signs of bone ...
https://en.wikipedia.org/wiki/Shar_Pei_fever
TetraphenylporphyrinTetraphenylporphyrin
Incorporation into Teteraphenylporphine in Dimethyl Sulfoxide". Inorg. Chem. 20 (11): 3763-3765. doi:10.1021/ic50225a038.{{cite ...
https://en.wikipedia.org/wiki/Tetraphenylporphyrin
Peptide synthesisPeptide synthesis
Tam JP, Wu CR, Liu W, Zhang JW (1991). "Disulfide bond formation in peptides by dimethyl sulfoxide. Scope and applications". J ... "Total synthesis of human insulin by regioselective disulfide formation using the silyl chloride-sulfoxide method". Journal of ...
https://en.wikipedia.org/wiki/Peptide_synthesis
Acid strengthAcid strength
The following are strong acids in aqueous and dimethyl sulfoxide solution. The values of p K a {\displaystyle \mathrm {p} K_{{\ ... such as a molecule of water or dimethyl sulfoxide (DMSO), to such an extent that the concentration of the undissociated species ... An important example of a solvent which is more basic than water is dimethyl sulfoxide, DMSO, ( CH 3 ) 2 SO {\displaystyle {\ce ... "Acidity of strong acids in water and dimethyl sulfoxide". J. Phys. Chem. A. 120 (20): 3663-3669. Bibcode:2016JPCA..120.3663T. ...
https://en.wikipedia.org/wiki/Acid_strength
Tricarbon monoxideTricarbon monoxide
Dimethyl sulfoxide oxidises the CCCO ligand to carbon suboxide./ C3O deposits a reddish-black film on glass. The reaction of ... Roger Brown heated 3,5-dimethyl-1-propynolpyrazole to over 700 °C to make C3O. Also pyrolysis of 5,5'-bis(2,2-dimethyl-4,6- ...
https://en.wikipedia.org/wiki/Tricarbon_monoxide
Perchloric acidPerchloric acid
"Acidity of Strong Acids in Water and Dimethyl Sulfoxide". The Journal of Physical Chemistry A. American Chemical Society (ACS ...
https://en.wikipedia.org/wiki/Perchloric_acid
Transition metal sulfoxide complexTransition metal sulfoxide complex
The most common sulfoxide ligand is dimethyl sulfoxide (dmso). Many sulfoxides are known because an enormous range of organic ... Chiral sulfoxides are configurationally stable. One example is methyl phenyl sulfoxide. Sulfoxides can bind to metals by the ... S-bonded sulfoxides are only found for soft metal centers, such as Ru(II). Complexes with both O- and S-bonded sulfoxide ... A transition metal sulfoxide complex is a coordination complex containing one or more sulfoxide ligands. The inventory is large ...
https://en.wikipedia.org/wiki/Transition_metal_sulfoxide_complex
DMSO reductaseDMSO reductase
... is a molybdenum-containing enzyme that catalyzes reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS ... "Direct oxygen atom transfer in the mechanism of action of Rhodobacter sphaeroides dimethyl sulfoxide reductase", Journal of the ... "Crystal structure of dimethyl sulfoxide reductase from Rhodobacter capsulatus at 1.88 A resolution". Journal of Molecular ...
https://en.wikipedia.org/wiki/DMSO_reductase
PyrobaculumPyrobaculum
Multiple dimethyl sulfoxide-molybdopterin (DMSO-MPT) oxidoreductase genes, which are implicated in the reduction of sulfur and ...
https://en.wikipedia.org/wiki/Pyrobaculum
SulfoxideSulfoxide
For example, dimethyl sulfide is oxidized to dimethyl sulfoxide and then further to dimethyl sulfone. Unsymmetrical sulfides ... and dimethyl sulfoxide (DMSO), a common solvent. Sulfoxides feature relatively short S-O distances. In DMSO, the S-O distance ... Thomas R, Shoemaker CB, Eriks K (1966). "The Molecular and Crystal Structure of Dimethyl Sulfoxide, (H3C)2SO". Acta Crystallogr ... Sulfoxides are oxidized derivatives of sulfides. Examples of important sulfoxides are alliin, a precursor to the compound that ...
https://en.wikipedia.org/wiki/Sulfoxide
Lead(II) iodideLead(II) iodide
S The sulfur is then washed with dimethyl sulfoxide. Lead iodide prepared from cold solutions of Pb2+ and I− salts usually ...
https://en.wikipedia.org/wiki/Lead(II)_iodide
Per- and polyfluoroalkyl substancesPer- and polyfluoroalkyl substances
The study reported that heating PFCAs in an 8 to 1 mixture of dimethyl sulfoxide and water at 80-120 °C (176-248 °F) in the ... via heating in a polar aprotic solvent such as dimethyl sulfoxide. ...
https://en.wikipedia.org/wiki/Per-_and_polyfluoroalkyl_substances
Ionic liquidIonic liquid
IL 1-butyl-3-methylimidazolium chloride dissolves freeze dried banana pulp and with an additional 15% dimethyl sulfoxide, lends ...
https://en.wikipedia.org/wiki/Ionic_liquid
Paint stripperPaint stripper
Dimethyl sulfoxide is a less toxic alternative solvent used in some formulations. Unfortunately, these alternative stripping ... often dimethyl esters of shorter dicarboxylic acids, sometimes aminated, for example, adipic acid or glutamic acid), aromatic ...
https://en.wikipedia.org/wiki/Paint_stripper
Paul Marks (scientist)Paul Marks (scientist)
MSKCC Paul Marks Prize website Marks, P. A.; Breslow, R. (2007). "Dimethyl sulfoxide to vorinostat: Development of this histone ...
https://en.wikipedia.org/wiki/Paul_Marks_(scientist)
Finkelstein reactionFinkelstein reaction
Such reactions usually employ polar solvents such as dimethyl formamide, ethylene glycol, and dimethyl sulfoxide. Alkyl halides ...
https://en.wikipedia.org/wiki/Finkelstein_reaction
Reversible inhibition of sperm under guidanceReversible inhibition of sperm under guidance
... with 120 µl of the solvent dimethyl sulfoxide. The copolymer is made by irradiation of the two monomers with a dose of 0.2 to ...
https://en.wikipedia.org/wiki/Reversible_inhibition_of_sperm_under_guidance
DictyoptereneDictyopterene
... A Dictyopterene B Dictyopterene C Dictyopterene C' Dictyopterene D (pre-ectocarpene) Dimethyl sulfide Ectocarpene ... "MIRC reactions using sulfoxides and synthesis of dictyopterene A". Arkivoc (vi): 91-103. ISSN 1424-6376. v t e (All articles ...
https://en.wikipedia.org/wiki/Dictyopterene
Sucrose estersSucrose esters
... but was later substituted with dimethyl sulfoxide or DMSO, which is less hazardous and cheaper. This process produces a mixture ...
https://en.wikipedia.org/wiki/Sucrose_esters
MTT assayMTT assay
A solubilization solution (usually either dimethyl sulfoxide, an acidified ethanol solution, or a solution of the detergent ...
https://en.wikipedia.org/wiki/MTT_assay
Ganem oxidationGanem oxidation
The reaction is an enhancement of the Kornblum oxidation protocol, which was originally developed using dimethyl sulfoxide or ...
https://en.wikipedia.org/wiki/Ganem_oxidation
Denaturation (biochemistry)Denaturation (biochemistry)
... dimethyl sulfoxide (DMSO), propylene glycol, and urea. These chemical denaturing agents lower the melting temperature (Tm) by ...
https://en.wikipedia.org/wiki/Denaturation_(biochemistry)
Pentavalent uranyl complexesPentavalent uranyl complexes
Dimethyl Sulfoxide orN,N-Dimethylformamide)". Inorg. Chem. 42 (4): 1031-1038. doi:10.1021/ic0260926. PMID 12588135. Mizuoka, K ...
https://en.wikipedia.org/wiki/Pentavalent_uranyl_complexes
Dinoroseobacter shibaeDinoroseobacter shibae
... shibae is able to grow anaerobically using electron acceptors nitrate and dimethyl sulfoxide. It has a complete denitrification ...
https://en.wikipedia.org/wiki/Dinoroseobacter_shibae
Solvent effectsSolvent effects
... and dimethyl sulfoxide (DMSO) and water. Many carbonyl compounds exhibit keto-enol tautomerism. This effect is especially ...
https://en.wikipedia.org/wiki/Solvent_effects
AmyloseAmylose
Molecular Weight and Solubility in Dimethyl Sulfoxide-Based Solvents". Journal of Agricultural and Food Chemistry. 54 (6): 2320 ...
https://en.wikipedia.org/wiki/Amylose
Wishin and Hopin (Greys Anatomy)Wishin' and Hopin' (Grey's Anatomy)
... was in fact the solvent dimethyl sulfoxide. Ellis is diagnosed with a heart condition, in which surgery or medication are ...
https://en.wikipedia.org/wiki/Wishin'_and_Hopin'_(Grey's_Anatomy)
SulfoleneSulfolene
... in replacement for dimethyl sulfoxide (DMSO), which is often used but difficult to separate and poorly reusable. As a model ...
https://en.wikipedia.org/wiki/Sulfolene
CurcuminoidCurcuminoid
... s are soluble in dimethyl sulfoxide (DMSO), acetone and ethanol, but are poorly soluble in lipids. It is possible to ...
https://en.wikipedia.org/wiki/Curcuminoid
Sulfate-reducing microorganismSulfate-reducing microorganism
... and dimethyl sulfoxide (DMSO). In terms of electron donor, this group contains both organotrophs and lithotrophs. The ...
https://en.wikipedia.org/wiki/Sulfate-reducing_microorganism
SoringSoring
Dimethyl sulfoxide (DMSO) is sometimes added to increase the effect. The treated area is then often wrapped in plastic while ...
https://en.wikipedia.org/wiki/Soring
Gaylord Chemical CorporationGaylord Chemical Corporation
The company has manufactured dimethyl sulfoxide (DMSO) and dimethyl sulfide (DMS) continuously since the early 1960s. Prior to ... The crude dimethyl sulfide product was purified by distillation and could then be used to produce DMSO. When Gaylord closed its ... The company maintains both Kosher and Halal certificates for its facility, due in part to the use of dimethyl sulfide (DMS) as ... The chemical process formerly used in Bogalusa to manufacture DMSO and dimethyl sulfide (DMS) was unique in that it ultimately ...
https://en.wikipedia.org/wiki/Gaylord_Chemical_Corporation
NitroethaneNitroethane
The Kornblum modification of this reaction uses sodium nitrite in either a dimethyl sulfoxide or dimethylformamide solvent. Via ... Establishment of an absolute scale of acidities in dimethyl sulfoxide solution". Journal of the American Chemical Society. 97 ( ...
https://en.wikipedia.org/wiki/Nitroethane
BismuthBismuth
Näslund, Jan; Persson, Ingmar; Sandström, Magnus (2000). "Solvation of the Bismuth(III) Ion by Water, Dimethyl Sulfoxide, N,N'- ...
https://en.wikipedia.org/wiki/Bismuth
Dimethyl sulfoxide anhydrous, = 99.9 67-68-5Dimethyl sulfoxide anhydrous, = 99.9 67-68-5
Dimethyl sulfoxide anhydrous, ≥99.9%; CAS Number: 67-68-5; EC Number: 200-664-3; Synonyms: DMSO; Linear Formula: (CH3)2SO; find ... For information on dimethyl sulfoxide miscibility, please visit the following link:. Dimethyl Sulfoxide Miscibility/ ... Dimethyl Sulfoxide is an apolar protic solvent that is generally used as a reaction medium and reagent in organic reactions. ... Dimethyl Sulfoxide may be used as an oxidant for the conversion of isonitriles into isocyanates. DMSO activated by oxalyl ...
https://www.sigmaaldrich.com/BR/pt/product/sial/276855
Domoso (Dimethyl Sulfoxide) PfizerDomoso (Dimethyl Sulfoxide) Pfizer
G04BX13 - Dimethyl Sulfoxide*M02AX03 - Dimethyl Sulfoxide. Pharmaceutical companies: manufacturers, researchers, developers, ... Dimethyl Sulfoxide. Available forms, composition and doses of Domoso:. *Gel; Topical; Dimethyl Sulfoxide 90%*Solution; Topical ...
https://drugs-about.com/drugs-d/domoso.html
Dimethyl Sulfoxide Badge, Lab Analysis Included - AFC InternationalDimethyl Sulfoxide Badge, Lab Analysis Included - AFC International
Dimethyl Sulfoxide Badge, Lab Analysis Included quantity. Add to cart. SKU: OV-325 Categories: Advanced Chemical Sensors Inc, ...
https://afcintl.com/p/dimethyl-sulfoxide-badge-lab-analysis-included/
Dimethyl sulfoxide influx in turbot embryos exposed to a vitrification protocol | - CCMARDimethyl sulfoxide influx in turbot embryos exposed to a vitrification protocol | - CCMAR
Cabrita, E, Robles, V, Chereguini, O, de Paz, P, Anel, L, Herráez, ...
https://ccmar.ualg.pt/en/node/4833
DIMETHYL SULFOXIDE 67-68-5, China DIMETHYL SULFOXIDE 67-68-5 Manufacturers, China DIMETHYL SULFOXIDE 67-68-5 Suppliers -...
... provide DIMETHYL SULFOXIDE 67-68-5 product and the products related with China DIMETHYL SULFOXIDE 67-68-5 - phytotechlab ... China DIMETHYL SULFOXIDE 67-68-5 Suppliers and China DIMETHYL SULFOXIDE 67-68-5 Manufacturers, ... Dimethyl sulfoxide;DMSO;Methyl sulphoxide;methyl sulfoxide B&J brand 1 L;methyl sulfoxide absolute over molecular sieve (H2O ... Send your inquiry to DIMETHYL SULFOXIDE supplier. Enter your inquiry here and then click Send. Enter between 20 to 3,000 ...
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ChemIDplus - 67-68-5 - IAZDPXIOMUYVGZ-UHFFFAOYSA-N - Dimethyl sulfoxide [USAN:USP:INN:BAN] - Similar structures search,...ChemIDplus - 67-68-5 - IAZDPXIOMUYVGZ-UHFFFAOYSA-N - Dimethyl sulfoxide [USAN:USP:INN:BAN] - Similar structures search,...
Dimethyl sulfoxide [USAN:USP:INN:BAN] - Similar structures search, synonyms, formulas, resource links, and other chemical ... Substance Name: Dimethyl sulfoxide [USAN:USP:INN:BAN]. RN: 67-68-5. UNII: YOW8V9698H. InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N. ... Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation. ...
https://chem.nlm.nih.gov/chemidplus/rn/67-68-5
Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive...Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive...
Dimethyl sulfoxide (DMSO) is frequently used at a concentration of up to 95% in the formulation of antiherpetic agents because ... From: Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive ...
https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-2-9/figures/4
Dimethyl Sulfoxide CAS 67-68-5 | Odour Threshold ValueDimethyl Sulfoxide CAS 67-68-5 | Odour Threshold Value
... for Dimethyl Sulfoxide CAS 67-68-5. Download free legacy OTVs or order a traceable EROM OTV value measured according to ... Dimethyl Sulfoxide CAS 67-68-5. 10,00€. - 2.000,00€. The OTV C value is available for free. You can access the Free OTV value ...
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Effect of fructose, sucrose, and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. :: MPG.PuReEffect of fructose, sucrose, and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. :: MPG.PuRe
... and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. ... Effect of fructose, sucrose, and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. Krasteva, N., Krustev, R ... and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. The Journal of Physical Chemistry B, 105(6), 1185-1190 ...
https://pure.mpg.de/pubman/faces/ViewItemFullPage.jsp?itemId=item_1930180
Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats<...
Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats. Inflammation. 2017 Apr 1;40 ... Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats. / Tsung, Yu Chi; Chung, ... Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats. In: Inflammation. 2017 ; ... Tsung, YC, Chung, CY, Wan, HC, Chang, YY, Shih, PC, Hsu, HS, Kao, MC & Huang, CJ 2017, Dimethyl Sulfoxide Attenuates Acute ...
https://tmu.pure.elsevier.com/en/publications/dimethyl-sulfoxide-attenuates-acute-lung-injury-induced-by-hemorr
China Shandong Shengtai instrument co.,ltd latest company cases about Dimethyl sulfoxide crystal point tester solutionChina Shandong Shengtai instrument co.,ltd latest company cases about Dimethyl sulfoxide crystal point tester solution
... ltd latest company case about Dimethyl sulfoxide crystal point tester solution. ... dimethyl sulfoxide) required ℃ :. ≥ 18.35, so anhydride level of dimethyl sulfoxide crystallization point tester needs to use a ... Dimethyl sulfoxide in liquid form is highly associative.. Polar solvents have strong water absorption and permeability to the ... Abstract: Properties of dimethyl sulfoxide: a transparent, colorless, odorless, slightly bitter liquid, very low toxicity.. It ...
https://www.lab-testinstruments.com/cases/dimethyl-sulfoxide-crystal-point-tester-solution-2776.html
Macular Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agentsMacular Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agents
Lack of effect of dimethyl sulphoxide (DMSO) on amyloid deposits in lichen amyloidosis. Br J Dermatol. 1988 Sep. 119(3):409-10 ... Ozkaya-Bayazit E, Kavak A, Gungor H, Ozarmagan G. Intermittent use of topical dimethyl sulfoxide in macular and papular ... Pandhi R, Kaur I, Kumar B. Lack of effect of dimethylsulphoxide in cutaneous amyloidosis. J Dermatolog Treat. 2002 Mar. 13(1): ... DMSO, an oxidation product of dimethyl sulfide, is an exceptional solvent possessing a number of commercial uses. Not an FDA- ...
https://www.medscape.com/answers/1102860-174627/which-medications-in-the-drug-class-topical-anti-inflammatory-agents-are-used-in-the-treatment-of-macular-amyloidosis
Interstitial Cystitis Medication: Antihistamines, 1st Generation, Antidepressants, TCAs, Analgesics, Urinary, Urologics, Other,...Interstitial Cystitis Medication: Antihistamines, 1st Generation, Antidepressants, TCAs, Analgesics, Urinary, Urologics, Other,...
Instillation therapy may use dimethyl sulfoxide (DMSO). It may also use cauterizing agents for the removal of granulation ... Dimethyl sulfoxide (DMSO) provides anti-inflammatory action, membrane penetration, antifungal activity, cryoprotective effects ... Maintenance of the response to dimethyl sulfoxide treatment using hyperbaric oxygen in interstitial cystitis/painful bladder ...
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Dimethyl Sulfoxide,Methionine Sulfoxide,Aldicarb SulfoxideDimethyl Sulfoxide,Methionine Sulfoxide,Aldicarb Sulfoxide
Methionine Sulfoxide Causes severe irritation and burns. May Be harmful if swallowed. Avoid breathing vapor or dust. Use with ...
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DMSO 99.9% purity (Dimethyl sulfoxide, 100ml) | Theresa HiggoDMSO 99.9% purity (Dimethyl sulfoxide, 100ml) | Theresa Higgo
DMSO is an organo-sulfur compound with the formula (CH3)2SO. This by-product of the paper making process was discovered in Germany in the late 19th century. Its a colorless liquid that gained attention for its ability to penetrate skin and other biological membranes. It was discovered DMSO could be used as a transportation device to pass small molecules through skin. Since then, scientists have researched the potential benefits and risks of using DMSO to treat a variety of conditions. This research is ongoing. Benefits: DMSO has been used topically to decrease pain speed the healing of wounds muscle and skeletal injuries It is also used topically to treat painful conditions such as: headache inflammation osteoarthritis rheumatoid arthritis and severe facial pain called tic douloureu Application: DMSO is best applied with a neutral carrier, such as coconut oil.DMSO also assists topical products to penetrate the skin efficiently Recommended dosage: We recommend starting with one drop of DMSO added
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Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier<...Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier<...
Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier. / Neuwelt, E. A.; Barnett, P.; Barranger, J ... Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier. In: Unknown Journal. 1983 ; Vol. 12, No. 1 ... Neuwelt EA, Barnett P, Barranger J, McCormick C, Pagel M, Frenkel E. Inability of dimethyl sulfoxide and 5-fluorouracil to open ... Neuwelt, E. A., Barnett, P., Barranger, J., McCormick, C., Pagel, M., & Frenkel, E. (1983). Inability of dimethyl sulfoxide and ...
https://ohsu.pure.elsevier.com/en/publications/inability-of-dimethyl-sulfoxide-and-5-fluorouracil-to-open-the-bl-2
Global Dimethyl Sulfoxide Market Size, Share | Industry Report 2028Global Dimethyl Sulfoxide Market Size, Share | Industry Report 2028
Dimethyl Sulfoxide Market major factor expected to drive growth is increasing demand for dimethyl sulfoxide in pharmaceuticals ... Global Dimethyl Sulfoxide Market: Region Analysis. The dimethyl sulfoxide market in North America is expected to account for ... Global Dimethyl Sulfoxide Market: Overview. Dimethyl sulfoxide (DMSO) is an organic compound that contains sulfur and has ... Global Dimethyl Sulfoxide Market: Dynamics. Increasing demand for dimethyl sulfoxide in pharmaceuticals as a topical analgesic ...
https://marketresearch.biz/report/dimethyl-sulfoxide-market/covid-19-impact/
Sell Dimethyl Sulfoxide 100g - Kimia Farmasi | GAEL VADA INDONESIA TangerangSell Dimethyl Sulfoxide 100g - Kimia Farmasi | GAEL VADA INDONESIA Tangerang
Jual Dimethyl Sulfoxide 100ml - Kimia Farmasi dengan harga Rp 123.00 dari GAEL VADA INDONESIA ... Specification of Dimethyl Sulfoxide 100g - Kimia Farmasi. Selling Dimethyl Sulfoxide for all regions in Indonesia such as ...
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DMSQ - Dimethyl Sulphoxide Archives - Australian Pesticides MapDMSQ - Dimethyl Sulphoxide Archives - Australian Pesticides Map
Australia is the stolen lands of Aboriginal & Torres Strait Islander people and sovereignty of these lands was never ceded. We pay respect to Elders, past and present, and acknowledge the pivotal role that Aboriginal & Torres Strait Islander people continue to play within the Australian community. All content produced for australianmap.net is licensed ...
https://pesticides.australianmap.net/chemicals/dmsq-dimethyl-sulphoxide/
Registration Dossier - ECHARegistration Dossier - ECHA
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/15007/7/6/3
High Quality Dimethyl Sulfoxide Dmso Manufacturer and Supplier, Factory | Baoran ChemicalHigh Quality Dimethyl Sulfoxide Dmso Manufacturer and Supplier, Factory | Baoran Chemical
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Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution) for interstitial cystitis...
Dive into the research topics of Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution ... Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution) for interstitial cystitis/ ...
https://okayama.pure.elsevier.com/en/publications/efficacy-and-safety-of-intravesical-instillation-of-krp-116d-50-d/fingerprints/
Flammability limit - WikipediaFlammability limit - Wikipedia
Dimethyl sulfide IA −49 °C Dimethyl sulfoxide 2.6-3 42 IIIB 88-95 °C 215 °C ...
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DMSO, dimethyl sulfoxide; E, ethanol; G, glutaraldehyde; H, hypochlorite; I, incidin, IP, isopropanol; M, medium, M+, medium ...
https://wwwnc.cdc.gov/eid/article/22/9/16-0664-f1
A permeability barrier surrounds taste buds in lingual epitheliaA permeability barrier surrounds taste buds in lingual epithelia
Dimethyl Sulfoxide Grant support * R01 DC006308/DC/NIDCD NIH HHS/United States ...
https://pubmed.ncbi.nlm.nih.gov/25209263/?dopt=Abstract
Search ResultsSearch Results
Zha, Q.; Nishimura, T.; Meisels, G.G., Unimolecular dissociation of energy-selected dimethyl sulfoxide, Int. J. Mass Spectrom. ...
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Listing of Drugs Currently Regulated as New Drugs (The New Drugs List) - Canada.caListing of Drugs Currently Regulated as New Drugs (The New Drugs List) - Canada.ca
Dimethyl Sulfoxide. Dinoprostone. Diphenidol and its salts. Diphenoxylate and its salts. Dipivefrin and its salts. ...
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DMSOSulfideMethyl sulfoxideReagentSigma-AldrichSucroseAnti-inflammatoryAmyloidosisIndonesiaProductTesterLiquidSpecificationsChemical formulaEffectMarketProductsSolutionsApplicationRangeSolventMethanolSolventsCerebrospinal fluidTrehaloseSodiumIntravesicalSalmonellaPFASSerumNIOSHTopicalMutagenicityVehicle ControlSchiffNutritionalWaterSymptomsJournalStudies
DMSO17
  • Dimethyl sulfoxide (DMSO) possesses anti-inflammatory and antioxidative capacities. (elsevier.com)
  • DMSO, an oxidation product of dimethyl sulfide, is an exceptional solvent possessing a number of commercial uses. (medscape.com)
  • Amyloidosis presented with whitening and loss of hair which improved after dimethylsulfoxide (DMSO) treatment. (medscape.com)
  • Instillation therapy may use dimethyl sulfoxide (DMSO). (medscape.com)
  • It has been suggested that the intravenous administration of dimethyl sulfoxide (DMSO) or 5-fluorouracil (5-FU) can accomplish the same thing in a less invasive manner. (elsevier.com)
  • Dimethyl sulfoxide (DMSO) is an organic compound that contains sulfur and has colorless appearance and high melting point. (marketresearch.biz)
  • Moreover, rapid industrialization, increasing demand for electronic grade DMSO, and growing demand for dimethyl sulfoxide in chemicals, agrochemical, and others are among some of the other factors expected to fuel growth of the dimethyl sulfoxide market in years to come. (marketresearch.biz)
  • However, stringent regulations regarding use of DMSO for veterinary and pharmaceutical purposes is a major factor which may restrain growth of the dimethyl sulfoxide market. (marketresearch.biz)
  • The dimethyl sulfoxide market in North America is expected to account for major revenue share contribution in the target market, owing to increasing demand for pharmaceutical and electronic grade DMSO. (marketresearch.biz)
  • This study aimed to evaluate the effect of dentin pretreatment by Dimethyl Sulfoxide ( DMSO ) on the bond strength and microleakage of a universal bonding agent to dentin . (bvsalud.org)
  • The health effects reported by the health care worker s were thought to be associated with an activity specific to the BMT: the infusing of patients with a solution containing stem cells and dimethyl sulfoxide (DMSO). (cdc.gov)
  • Lack of effect of dimethyl sulphoxide (DMSO) on amyloid deposits in lichen amyloidosis. (medscape.com)
  • The drug was initially dissolved in dimethyl sulfoxide (DMSO) (final concentration was 2%) and brought to the final volume with corn oil. (springeropen.com)
  • The substances were tested at concentrations of up to 400 micrograms (microg) per plate using dimethyl-sulfoxide (DMSO) as the solvent and up to 2,000microg/plate using Tween-80 as the solvent. (cdc.gov)
  • MSM (methylsulfonylmethane) is a natural compound found in plants and animals, MSM is a normal oxidation product of dimethyl sulfoxide (DMSO), and is a part of the natural global sulfur cycle. (humannaturellc.com)
  • cheap jordans shoes DMSO (dimethyl sulfoxide) and selenium have proven strong in this area. (restorationministrie.se)
  • Apoptosis is the most well known processes by compounds were prepared as 3mg/ml concentration which cell death is mediated by at least 14 members of stock solutions in dimethyl sulfoxide (DMSO). (medicinelakex1.com)
Sulfide1
  • It is produced from dimethyl sulfide and by-product of the Kraft process in presence of oxygen or nitrogen dioxide. (marketresearch.biz)
Methyl sulfoxide1
Reagent1
  • Dimethyl Sulfoxide is an apolar protic solvent that is generally used as a reaction medium and reagent in organic reactions. (sigmaaldrich.com)
Sigma-Aldrich1
  • Diaminobenzidine tetrahydrochloride 58 sigma aldrich D9628-5G 3,4-Dihydroxy-L-phenylalanine 59 sigma aldrich 340200-25G 3-Amino-5-methylpyrazole 60 sigma aldrich 68524-100MG 4-(4-Hydroxyphenyl)-2-butanone 61 sigma aldrich D15405-5G 4,5-Diamino-2,6-dimercaptopyrimidine 62 sigma aldrich D17807-25G 4,5-Diamino-6-hydroxy-2-mercaptopyrimidine 63 sigma aldrich D176605-5G 4,5-Dimethyl-1,2-phenylenediamine 64 sigma aldrich D8417-5MG 4? (safirazmakian.com)
Sucrose1
  • Effect of fructose, sucrose, and dimethyl sulfoxide on the equilibrium thickness of DMPC foam films. (mpg.de)
Anti-inflammatory1
  • Increasing demand for dimethyl sulfoxide in pharmaceuticals as a topical analgesic, an antioxidant, and an anti-inflammatory is a major factor expected to drive growth of the target market in the next coming years. (marketresearch.biz)
Amyloidosis1
  • Ozkaya-Bayazit E, Kavak A, Gungor H, Ozarmagan G. Intermittent use of topical dimethyl sulfoxide in macular and papular amyloidosis. (medscape.com)
Indonesia1
  • Selling Dimethyl Sulfoxide for all regions in Indonesia such as Jakarta, Bandung, Bali, Medan, and other parts of Indonesia. (gudangbahankimia.com)
Product2
  • The global dimethyl sulfoxide market report has been segmented on the basis of product type, application, and region. (marketresearch.biz)
  • 2. Ideal substitute of highly toxic product such as phosgene, dimethyl sulfate, and methyl chloroformate. (sinochemi.com)
Tester1
  • 18.35, so anhydride level of dimethyl sulfoxide crystallization point tester needs to use a high-precision crystallization point tester to detect, the measurement accuracy must reach 0.01 degrees, ST406B automatic crystallization point determination meaning fully meet the standards and accuracy requirements. (lab-testinstruments.com)
Liquid1
Specifications1
  • The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. (lookchem.com)
Chemical formula1
Effect1
  • The effect of dentin surface pretreatment using dimethyl sulfoxide on the bond strength of a universal bonding agent to dentin. (bvsalud.org)
Market2
  • "Global Dimethyl Sulfoxide Market Analysis Trends, Applications, Analysis, Growth, and Forecast to 2028 " is a recent report generated by MarketResearch.biz. (marketresearch.biz)
  • Increasing demand for dimethyl sulfoxide as a solvent in chemical reactions owing to its various properties is another factor expected to support revenue growth of the global dimethyl sulfoxide market. (marketresearch.biz)
Products1
  • Crystallization point of dimethyl sulfoxide was determined according to GB/T7533 standard method for determination of crystallization point of organic chemical products. (lab-testinstruments.com)
Solutions1
  • Asphalt samples were extracted with methylene chloride, evaporated to dryness for total mass determination, and dosing solutions were prepared in dimethyl sulfoxide. (cdc.gov)
Application1
  • Ultrastructural studies of barrier restoration in epidermis of hairless mice following dimethyl sulfoxide application. (cdc.gov)
Range1
  • Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation. (nih.gov)
Solvent5
  • Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction. (sigmaaldrich.com)
  • Dimethyl sulfoxide is an organic compound that is used as a solvent for various applications. (remedysnutrition.com)
  • If the absorbance so measured exceeds 2.0 at any point in range 280-350 m[micro], inclusive, dilute the extract and the solvent control, respectively, to twice their volume with dimethyl sulfoxide and remeasure the absorbance. (fda.gov)
  • The mice were administrated daily with solvent dimethyl sulfoxide, EGCG, and EGCG-P separately through intraperitoneal injection for 20 days. (greenmedinfo.com)
  • Dichtel's team targeted this head group by heating the PFAS in dimethyl sulfoxide - an unusual solvent for PFAS destruction - with sodium hydroxide, a common reagent. (scitechdaily.com)
Methanol2
  • Bis(3,5-dimeth-oxy-2-{[2-(pyridin-2-yl)ethyl-imino-?N]-meth-yl}phenolato-?O)bis-(dimethyl sulfoxide)-manganese(III) perchlorate methanol 0.774-solvate. (omicsdi.org)
  • Safinamide mesylate is freely soluble in water, methanol and dimethyl sulfoxide. (rxlist.com)
Solvents1
  • 1,2,3,4-butanetetracarboxylic acid was used to partially crosslink the hydroxyl groups of cellulose, thereby changing mechanical properties of the membranes and the interactions with solvents, ethanol and dimethyl sulfoxide, and solutes. (metu.edu.tr)
Cerebrospinal fluid1
  • Cyclophosphamide plasma and cerebrospinal fluid kinetics with and without dimethyl sulfoxide. (sigmaaldrich.com)
Trehalose1
  • Cryopreservation of C. elegans and Other Nematodes with Dimethyl Sulfoxide and Trehalose. (nih.gov)
Sodium2
  • The efficacy of diclofenac sodium topical solution 1.5% w/w with dimethyl sulfoxide (TDiclo) has been established as superior to placebo and comparable with oral NSAIDs in the management of OA. (nih.gov)
  • Viscosities of the ternary solution dimethyl sulfoxide/water/sodium chloride at subzero temperatures and their application in cryopreservation. (iifiir.org)
Intravesical1
  • sup.4] Intravesical mitomycin, thiotepa and dimethyl sulfoxide have been reported as possible causative agents. (thefreedictionary.com)
Salmonella1
  • Genetic Toxicity Evaluation of Dimethyl Sulfoxide in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
PFAS1
  • Soaking carboxylic PFAS in dimethyl sulfoxide and then adding lye, water and heat causes "the carboxylic acid group that is found across this entire class of compounds to fall off," Dichtel said. (medshoppehhs.com)
Serum1
  • Rat hepatocytes were cryopreserved optimally by freezing them at 1 degrees C/min to -80 degrees C in cryoprotectant medium containing either 20% (v/v) dimethylsulfoxide (Me2SO) and 25% (v/v) fetal calf serum in Leibowitz L15 medium (Me2SO cryoprotectant) or 25% (v/v) vitrification solution (containing Me2SO, acetamide, propylene glycol and polyethylene glycol) in Leibowitz L15 medium (VS25). (nih.gov)
NIOSH1
  • Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). (lookchem.com)
Topical1
  • Ozkaya-Bayazit E, Kavak A, Gungor H, Ozarmagan G. Intermittent use of topical dimethyl sulfoxide in macular and papular amyloidosis. (medscape.com)
Mutagenicity1
  • An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dimethyl sulfoxide (67-68-5). (nih.gov)
Vehicle Control1
  • Dimethyl sulfoxide has been used as a vehicle control to culture and induce hepatic stellate cells (HSCs) activation in vivo . (sigmaaldrich.com)
Schiff1
  • The Zn atom in the title acetonitrile solvate, [Zn(C 34 H 42 N 4 O 2 )(C 2 H 6 OS)]·CH 3 CN, exists in a distorted square-pyramidal geometry with the basal plane defined by the N 2 O 2 atoms of the tetra-dentate Schiff base and with the dimethyl sulfoxide O atom in the apical position. (iucr.org)
Nutritional1
  • In the nutritional world, Dimethyl sulfoxide can be used topically to help with burns, wounds, and inflammation. (remedysnutrition.com)
Water1
  • Confusing cause and effect: Energy-entropy compensation in the preferential solvation of a nonpolar solute in dimethyl sulfoxide/water mixtures. (mpg.de)
Symptoms1
  • Dimethyl sulfoxide may help relieve symptoms. (medscape.com)
Journal1
  • Effects of Dimethyl Sulfoxide and Mutations on the Folding of Abeta(25-35) Peptide: Molecular Dynamics Simulations', Biomacromolecular Journal , 2(2), pp. 177-190. (bmmj.org)
Studies1
Macular Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agents
Macular Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agents (medscape.com)
DMSO 99.9% purity (Dimethyl sulfoxide, 100ml) | Theresa Higgo
DMSO 99.9% purity (Dimethyl sulfoxide, 100ml) | Theresa Higgo (healthwellnessandaesthetics.com)
Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories
Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories (cdc.gov)
(emedicine.medscape.com)
RCSB PDB - 7BLU: Notum_Maybridge_56
RCSB PDB - 7BLU: Notum_Maybridge_56 (rcsb.org)
RCSB PDB - 4J1C: CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((S)-2-amino-5,5-difluoro-4...
RCSB PDB - 4J1C: CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((S)-2-amino-5,5-difluoro-4... (rcsb.org)
RCSB PDB - 3G72: Design and Preparation of Potent, Non-Peptidic, Bioavailable Renin Inhibitors
RCSB PDB - 3G72: Design and Preparation of Potent, Non-Peptidic, Bioavailable Renin Inhibitors (rcsb.org)
PDF) Feasibility of using dried plant specimens for DNA barcoding. A case study of the Juncaceae
PDF) Feasibility of using dried plant specimens for DNA barcoding. A case study of the Juncaceae (researchgate.net)
Molecules | Free Full-Text | Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors...
Molecules | Free Full-Text | Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors... (mdpi.com)
Metilsulfonilmetano (MSM): MedlinePlus suplementos
Metilsulfonilmetano (MSM): MedlinePlus suplementos (medlineplus.gov)
Cancers | Free Full-Text | Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia
Cancers | Free Full-Text | Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia (mdpi.com)
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease | Neurology
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease | Neurology (n.neurology.org)
Plus it
Plus it (jpet.aspetjournals.org)
Bardoxolone methyl induces apoptosis and autophagy and inhibits epithe | DDDT
Bardoxolone methyl induces apoptosis and autophagy and inhibits epithe | DDDT (dovepress.com)
Plus it
Plus it (jpet.aspetjournals.org)
Stereodivergent total synthesis of rocaglaol initiated by synergistic dual-metal-catalyzed asymmetric allylation of benzofuran...
Stereodivergent total synthesis of rocaglaol initiated by synergistic dual-metal-catalyzed asymmetric allylation of benzofuran... (cell.com)
Interstitial cystitis: MedlinePlus Medical Encyclopedia
Interstitial cystitis: MedlinePlus Medical Encyclopedia (medlineplus.gov)
Tjp1 (tight junction protein 1) - Rat Genome Database
Tjp1 (tight junction protein 1) - Rat Genome Database (rgd.mcw.edu)
Search Results
Search Results (webbook.nist.gov)
Eastern Equine Encephalomyelitis Virus Infection in a Horse from California - Volume 8, Number 3-March 2002 - Emerging...
Eastern Equine Encephalomyelitis Virus Infection in a Horse from California - Volume 8, Number 3-March 2002 - Emerging... (wwwnc.cdc.gov)
Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome |...
Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome |... (nature.com)
Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia | Blood Cancer...
Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia | Blood Cancer... (nature.com)
Lichen Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agents
Lichen Amyloidosis Medication: Antihistamines, Topical anti-inflammatory agents (emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
Nonbacterial Prostatitis Medication: Antibiotics, Alpha-Adrenergic Blocking Agents, 5-Alpha Reductase Inhibitors, Nonsteroidal...
Nonbacterial Prostatitis Medication: Antibiotics, Alpha-Adrenergic Blocking Agents, 5-Alpha Reductase Inhibitors, Nonsteroidal... (emedicine.medscape.com)
(emedicine.medscape.com)
DailyMed - Search Results for Trametinib
DailyMed - Search Results for Trametinib (dailymed.nlm.nih.gov)
Oranges for Symptoms With Stem Cell Reinfusions
Oranges for Symptoms With Stem Cell Reinfusions (medscape.com)
The N-of-1 Clinical Trial
The N-of-1 Clinical Trial (medscape.com)