Tumors or cancer of the DIGESTIVE SYSTEM.
Diseases in any part of the GASTROINTESTINAL TRACT or the accessory organs (LIVER; BILIARY TRACT; PANCREAS).
A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.
Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)
Properties and processes of the DIGESTIVE SYSTEM and DENTITION as a whole or of any of its parts.
Properties and processes of the DIGESTIVE SYSTEM as a whole or of any of its parts.
Biological actions and events that constitute the functions of the DIGESTIVE SYSTEM.
An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.
Congenital structural abnormalities of the DIGESTIVE SYSTEM.
Methods and procedures for the diagnosis of diseases or dysfunction of the digestive system or its organs or demonstration of their physiological processes.
Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Tumors or cancer of the LIVER.
Tumors or cancer of the STOMACH.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.

Gastrointestinal surgical workload in the DGH and the upper gastrointestinal surgeon. (1/276)

Workload implications of upper gastrointestinal (UGI) subspecialisation within the district general hospital (DGH) have been assessed by prospective data collection over a 12-month period in a DGH with six general surgeons serving a population of 320,000. The single UGI surgeon (UGIS) performed all ten oesophageal resections, ten of 11 gastric resections for malignancy and all eight pancreatic operations. He also performed 91 of the 182 cholecystectomies, 164 of the 250 endoscopic retrograde cholangiopancreatograms (ERCP) and all endoscopic procedures for the palliation of unresected oesophageal tumours. The UGIS was responsible for the management of all patients with severe pancreatitis, yet he also performed 51 colorectal resections over the 12-month period. Successful management of severely ill patients with upper GI disease requires consultant supervision on a day-to-day basis. If such UGI disease is to be managed in the DGH, two surgeons with UGI experience will be required if high quality care and reasonable working conditions are to be achieved. Such UGIS will continue to perform some colorectal surgery.  (+info)

Role of the surgical trainee in upper gastrointestinal resectional surgery. (2/276)

The 'New Deal' set out by the Department of Health in 1991, together with the introduction of specialist 6-year training grades by Calman in 1993, has resulted in a decrease in available training time for surgeons in the UK. There is also an emerging belief that surgical procedures performed by trainees might compromise patient outcome. This study examines the level of trainee experience in a specialist gastrointestinal unit and whether operation by a trainee surgeon adversely affects patient outcome. All patients in the University Department of Surgery, Royal Infirmary, Edinburgh, undergoing oesophagogastric, hepatic or pancreatic resection between January 1994 and December 1996 were entered into the study. The early clinical outcome (in-hospital mortality and morbidity, considered in three groups: anastomotic leak, other technique-related complications and non-technique-related complications) was evaluated with regard to the grade of surgeon (consultant or trainee) performing the operation. Of the 222 patients undergoing major upper gastrointestinal resection during the study period, 100 (45%) were operated on by trainees. Trainees were assisted and closely supervised by consultants in all but six resections. There was no major difference in mortality rate (consultant, 4.1% vs trainee, 5%), incidence of non-technique-related complications (consultant, 6.7% vs trainee, 7.1%), anastomotic leaks (consultant, 10.7% vs trainee, 5%) or technique-related complications (consultant, 18.9% vs trainee, 15%) between the two grades of surgeon. In a specialist unit, the early clinical outcome of patients undergoing major upper gastrointestinal resection by supervised trainees is no worse than in those operated on by consultants. Participation of trainees in such complex procedures enhances surgical training and does not jeopardise patient care.  (+info)

O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair. (3/276)

Early phase evaluation of anticancer drugs has traditionally used toxicity (usually hematological) rather than efficacy end points to establish appropriate dosing schedules. To establish a biochemical efficacy end point for overcoming alkylguanine DNA alkyltransferase (AGT)-mediated tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea, we performed a novel dose escalation clinical trial for the AGT-depleting agent O6-benzylguanine (BG). The dose of BG required to deplete AGT to undetectable levels (BMD(T)) in sequential computed tomography-guided tumor tissue biopsies before BG and 18 h after BG was determined. Thirty patients received doses of BG ranging from 10 to 120 mg/m2. In tumor tissue, AGT depletion >86% of baseline was demonstrated at all doses tested. Residual tumor AGT activity, present 18 h after BG doses of 10-80 mg/m2, was eliminated at the 120 mg/m2 dose and is thus the BMD(T) of BG. BG pharmacokinetics are characterized by the rapid, dose-independent clearance of BG from plasma Metabolism of BG to its biologically active metabolite, 8-oxo-benzylguanine (8-oxo-BG), was found. The t(1/2) of 8-oxo-BG is longer than BG. Plasma concentrations of 8-oxo-BG well above 200 ng/ml 18 h after the end of the BG infusion were observed at the highest dose levels tested and appeared to correlate with depletion of AGT activity to undetectable levels in tumor tissue. AGT activity in peripheral blood mononuclear cells at baseline did not correlate with tumor tissue AGT activity. Depletion of AGT activity to undetectable levels in peripheral blood mononuclear cells occurred at lower doses and was not a reliable predictor for tumor tissue depletion. No serious side effects were observed with administration of BG alone or in combination with 13 mg/m2 1,3-bis(2-chloroethyl)-1-nitrosourea. This is the first clinical study in which biochemical analyses from pre- and posttreatment tumor biopsies have been used as an efficacy end point for the clinical development of an anticancer agent. From our tumor tissue biopsy data, we have established that a BG dose of 120 mg/m2 infused over 1 h should be used in Phase II clinical trials.  (+info)

Multi-institutional randomized clinical study on the comparative effects of intracavital chemotherapy alone versus immunotherapy alone versus immunochemotherapy for malignant effusion. (4/276)

The current prospective randomized study was designed to compare the effects of intracavitary (i.c.) chemotherapy vs immunotherapy vs immunochemotherapy for malignant effusion. Between 1992 and 1995, a total of 42 patients with malignant effusion were registered, and 41 patients were eligible for statistical analysis. The primary diseases of the eligible patients included 27 gastric, four colorectal, four pancreatic, three lung, two liver and one oesophageal cancers. The patients with malignant effusion were randomly assigned into one of three i.c. therapeutic regimens: chemotherapy alone with weekly injection of anticancer agents (ACAs: cisplatin, mitomycin-C, adriamycin, etc.) (Group A, n = 13); immunotherapy alone with weekly injection of streptococcal preparation OK-432 (Group B, n = 14); or immunochemotherapy with ACAs and OK-432 (Group C, n = 14). The response of the effusion, patient survival and the kinetics of cytokines in the effusion were compared. There were no differences in the patients' backgrounds. The side-effects of the regimens included pain, anorexia, fever, leucopenia and anaemia and there were no differences in their incidence among the three groups. One patient died after cisplatin (CDDP) administration in Group A. Cytologic examination revealed that tumour cells in the effusion disappeared in 23% of Group A cases, 36% of Group B cases and 36% of Group C cases. The malignant effusion did not disappear in any of the Group A cases; however, the effusion disappeared in 29% of Group B cases and 43% of Group C cases (P = 0.03, Group A vs Group C). Furthermore, the 50% survival period was 1.6 months for Group A, 2.4 months for Group B and 3.5 months for Group C. The 6-month survival rate was 7% for Group A, 6% for Group B and 34% for Group C, and the 1-year survival rate was 0%, 0% and 17% respectively (P = 0.048, Group A vs Group C by the log-rank test). The analysis of the cytokine kinetics revealed a prominent increase in the level of interleukin-6 in the effusion in Group C. These results suggest that i.c. immunochemotherapy with OK-432 and ACAs may be more beneficial than i.c. chemotherapy alone or immunotherapy alone.  (+info)

Analyzing health surveys for cancer-related objectives. (5/276)

Large-scale health surveys conducted by government agencies record information on a large number of health-related variables. We review the use of these data for performing analyses that address cancer-related objectives. After describing the conduct of a large-scale health survey (the third National Health and Nutrition Examination Survey [NHANES III]), we discuss some of the issues involved in analyzing data collected in such a survey. In particular, the use of sample weights in the analysis and the importance of accounting for the complex survey design when estimating standard errors are discussed. Six applications are then presented that involve the following: 1) estimating demographic factors associated with snuff use, 2) estimating the association of type of health insurance with the probability of receiving a digital rectal examination, 3) estimating the association of body iron stores with the probability of later developing cancer, 4) estimating the changing rates of mammography screening in the United States between 1987 and 1992, 5) evaluating smoking and alcohol consumption as risk factors for digestive cancer by use of a population-based, case-control study, and 6) evaluating a randomized community-intervention experiment to encourage smoking cessation. These applications use data from the National Health Interview Survey, the NHANES I Epidemiologic Followup Study, the 1986 National Mortality Followback Survey, and the Community Intervention Trial for Smoking Cessation. The availability of public-use data files is discussed for surveys sponsored by the U.S. government that collect health-related information. We demonstrate that statistical methods and computer software are available for analyzing public-use data files of surveys to address different types of cancer-related objectives.  (+info)

High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion. (6/276)

The purpose of the study was to examine inter- and intrapatient variation in 5-fluorouracil (5-FU) plasma concentrations in adult cancer patients receiving a 3-day drug infusion. Fourteen patients received 1266 mg/m2 N-(phosphonacetyl)-L-aspartate (PALA) infused i.v. over 15 min on day 1, followed immediately by a loading dose of 500 mg/m2 calcium leucovorin over 30 min. Then a prolonged infusion of leucovorin at 500 mg/m2/day and 5-FU at 1750 mg/m2/day was administered as either a constant rate or as a circadian infusion over 72 h. During constant rate infusions, 5-FU concentrations within individuals varied by 1.7-fold, but no uniform time of peak or trough concentration was observed. Transformation of these data by setting the time of peak to 0 h and by expressing concentrations as the percentage of the 24-h mean value revealed a nonrandom distribution of the time from peak to trough with a median time of 12 h (P = 0.027). These transformed data were also successfully fit to a circadian cosinor function (P < 0.001). During multiple constant rate 5-FU infusions, the intrapatient variability was high; the times of peak 5-FU concentration occurred at the same approximate sampling time 43% of the time, and troughs coincided 17% of the time. No difference in clinical toxicity was observed when matched constant rate and circadian infusions of 5-FU were compared. High inter- and intrapatient variability exists in 5-FU plasma concentrations in adult cancer patients during constant rate infusions with no evidence of a consistent circadian rhythm in untransformed data.  (+info)

Fish consumption and cancer risk. (7/276)

BACKGROUND: Although several studies have investigated the relation between fish consumption and the risk of cardiovascular diseases, less attention has been paid to the relation between fish consumption and cancer risk. OBJECTIVE: The relation between frequency of consumption of fish and risk of selected neoplasms was analyzed by using data from an integrated series of case-control studies conducted in northern Italy between 1983 and 1996. DESIGN: The overall data set included the following incident, histologically confirmed neoplasms: oral cavity and pharynx (n = 181), esophagus (n = 316), stomach (n = 745), colon (n = 828), rectum (n = 498), liver (n = 428), gallbladder (n = 60), pancreas (n = 362), larynx (n = 242), breast (n = 3412), endometrium (n = 750), ovary (n = 971), prostate (n = 127), bladder (n = 431), kidney (n = 190), thyroid (n = 208), Hodgkin disease (n = 80), non-Hodgkin lymphomas (n = 200), and multiple myelomas (n = 120). Control subjects were 7990 patients admitted for acute, nonneoplastic conditions unrelated to long-term modifications of diet. Odds ratios (ORs) were computed for subsequent levels of fish consumption compared with no or occasional consumption (<1 serving/wk) by using multiple logistic regression, including terms for several covariates. RESULTS: There was a consistent pattern of protection against the risk of digestive tract cancers with fish consumption: oral cavity and pharynx, OR = 0.5 for the highest compared with the lowest level of consumption; esophagus, OR = 0.6; stomach, OR = 0.7; colon, OR = 0.6; rectum, OR = 0.5; and pancreas, OR = 0.7. There were inverse trends in risk of larynx (OR = 0.7), endometrial (OR = 0.8), and ovarian (OR = 0.7) cancers and multiple myeloma (OR = 0.5). No pattern of cancer risk in relation to fish consumption was observed for cancers of the liver, gallbladder, breast, bladder, kidney, or thyroid or for lymphomas. CONCLUSION: This study suggests that the consumption of even relatively small amounts of fish is a favorable indicator of the risk of several cancers, especially of the digestive tract.  (+info)

Nuclear retinoid acid receptor beta in bronchial epithelium of smokers before and during chemoprevention. (8/276)

BACKGROUND: Retinoids can reverse neoplastic lesions and prevent second primary tumors in the aerodigestive tract. These effects are thought to be mediated by nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), each receptor group including three subtypes (alpha, beta, and gamma). Previously, we found that RARbeta expression was suppressed in lung cancer. In this study, we investigated whether expression of RARbeta is modulated by chemopreventive intervention. METHODS: Using in situ hybridization, we analyzed RARbeta messenger RNA (mRNA) expression in bronchial biopsy specimens from heavy smokers, at baseline and after 6 months of treatment with 13-cis-retinoic acid (13-cis-RA) or placebo. Since we had previously detected RARbeta expression in 90% of bronchial specimens from nonsmokers, we considered loss of RARbeta mRNA expression in at least one of six biopsy specimens at baseline in this study to be aberrant. RESULTS: RARbeta mRNA expression was aberrant in 30 (85.7%) of 35 subjects in the 13-cis-RA group and in 24 (72.7%) of 33 subjects in the placebo group. After 6 months of 13-cis-RA treatment, the number of subjects who were RARbeta positive in all six biopsy specimens increased from five of 35 to 13 of 35 (2.6-fold), so that the percentage of individuals with aberrant RARbeta expression decreased to 62.9% (22 of 35), which represents a statistically significant difference from baseline expression (two-sided P =.01). In the placebo group, no statistically significant difference in RARbeta expression was observed between baseline and 6 months. RARbeta expression was not related to current smoking status or reversal of squamous metaplasia. CONCLUSIONS: These results indicate that RARbeta is an independent marker of response to 13-cis-RA and may serve as an intermediate biomarker in chemoprevention trials of upper aerodigestive tract cancers.  (+info)

'Digestive System Neoplasms' refer to new and abnormal growths of tissue in the digestive system that can be benign or malignant. These growths are also known as tumors, and they can occur in any part of the digestive system, including the esophagus, stomach, small intestine, large intestine (colon and rectum), liver, bile ducts, pancreas, and gallbladder. Neoplasms in the digestive system can interfere with normal digestion and absorption of nutrients, cause bleeding, obstruct the digestive tract, and spread to other parts of the body (metastasis) if they are malignant.

Benign neoplasms are not cancerous and do not usually spread to other parts of the body. They can often be removed surgically and may not require further treatment. Malignant neoplasms, on the other hand, are cancerous and can invade nearby tissues and organs and spread to other parts of the body. Treatment for malignant neoplasms in the digestive system typically involves a combination of surgery, radiation therapy, and chemotherapy.

The causes of digestive system neoplasms are varied and include genetic factors, environmental exposures, lifestyle factors (such as diet and smoking), and infectious agents. Prevention strategies may include maintaining a healthy diet, avoiding tobacco and excessive alcohol consumption, practicing safe sex, getting vaccinated against certain viral infections, and undergoing regular screenings for certain types of neoplasms (such as colonoscopies for colorectal cancer).

The digestive system, also known as the gastrointestinal (GI) tract, is a series of organs that process food and liquids into nutrients and waste. Digestive system diseases refer to any conditions that affect the normal functioning of this system, leading to impaired digestion, absorption, or elimination of food and fluids.

Some common examples of digestive system diseases include:

1. Gastroesophageal Reflux Disease (GERD): A condition where stomach acid flows back into the esophagus, causing symptoms such as heartburn, chest pain, and difficulty swallowing.
2. Peptic Ulcer Disease: Sores or ulcers that develop in the lining of the stomach or duodenum, often caused by bacterial infection or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
3. Inflammatory Bowel Disease (IBD): A group of chronic inflammatory conditions that affect the intestines, including Crohn's disease and ulcerative colitis.
4. Irritable Bowel Syndrome (IBS): A functional gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel habits.
5. Celiac Disease: An autoimmune disorder where the ingestion of gluten leads to damage in the small intestine, impairing nutrient absorption.
6. Diverticular Disease: A condition that affects the colon, characterized by the formation of small pouches or sacs (diverticula) that can become inflamed or infected.
7. Constipation: A common digestive system issue where bowel movements occur less frequently than usual or are difficult to pass.
8. Diarrhea: Loose, watery stools that occur more frequently than normal, often accompanied by cramps and bloating.
9. Gallstones: Small, hard deposits that form in the gallbladder, causing pain, inflammation, and potential blockages of the bile ducts.
10. Hepatitis: Inflammation of the liver, often caused by viral infections or toxins, leading to symptoms such as jaundice, fatigue, and abdominal pain.

These are just a few examples of digestive system disorders that can affect overall health and quality of life. If you experience any persistent or severe digestive symptoms, it is important to seek medical attention from a healthcare professional.

The digestive system is a complex group of organs and glands that process food. It converts the food we eat into nutrients, which the body uses for energy, growth, and cell repair. The digestive system also eliminates waste from the body. It is made up of the gastrointestinal tract (GI tract) and other organs that help the body break down and absorb food.

The GI tract includes the mouth, esophagus, stomach, small intestine, large intestine, and anus. Other organs that are part of the digestive system include the liver, pancreas, gallbladder, and salivary glands.

The process of digestion begins in the mouth, where food is chewed and mixed with saliva. The food then travels down the esophagus and into the stomach, where it is broken down further by stomach acids. The digested food then moves into the small intestine, where nutrients are absorbed into the bloodstream. The remaining waste material passes into the large intestine, where it is stored until it is eliminated through the anus.

The liver, pancreas, and gallbladder play important roles in the digestive process as well. The liver produces bile, a substance that helps break down fats in the small intestine. The pancreas produces enzymes that help digest proteins, carbohydrates, and fats. The gallbladder stores bile until it is needed in the small intestine.

Overall, the digestive system is responsible for breaking down food, absorbing nutrients, and eliminating waste. It plays a critical role in maintaining our health and well-being.

Nervous system neoplasms are abnormal growths or tumors that occur within the nervous system, which includes the brain, spinal cord, and peripheral nerves. These tumors can be benign (non-cancerous) or malignant (cancerous), and their growth can compress or infiltrate surrounding tissues, leading to various neurological symptoms. The causes of nervous system neoplasms are not fully understood but may involve genetic factors, exposure to certain chemicals or radiation, and certain viral infections. Treatment options depend on the type, location, and size of the tumor and can include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Peripheral nervous system (PNS) neoplasms refer to tumors that originate in the peripheral nerves, which are the nerves outside the brain and spinal cord. These tumors can be benign or malignant (cancerous). Benign tumors, such as schwannomas and neurofibromas, grow slowly and do not spread to other parts of the body. Malignant tumors, such as malignant peripheral nerve sheath tumors (MPNSTs), can invade nearby tissues and may metastasize (spread) to other organs.

PNS neoplasms can cause various symptoms depending on their location and size. Common symptoms include pain, weakness, numbness, or tingling in the affected area. In some cases, PNS neoplasms may not cause any symptoms until they become quite large. Treatment options for PNS neoplasms depend on several factors, including the type, size, and location of the tumor, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

The digestive system is a series of organs and glands that work together to break down food into nutrients, which the body can absorb and use for energy, growth, and cell repair. The process begins in the mouth, where food is chewed and mixed with saliva, which contains enzymes that begin breaking down carbohydrates.

The oral physiological phenomena refer to the functions and processes that occur in the mouth during eating and digestion. These include:

1. Ingestion: The process of taking food into the mouth.
2. Mechanical digestion: The physical breakdown of food into smaller pieces by chewing, which increases the surface area for enzymes to act on.
3. Chemical digestion: The chemical breakdown of food molecules into simpler substances that can be absorbed and utilized by the body. In the mouth, this is initiated by salivary amylase, an enzyme found in saliva that breaks down starches into simple sugars.
4. Taste perception: The ability to detect different flavors through specialized taste buds located on the tongue and other areas of the oral cavity.
5. Olfaction: The sense of smell, which contributes to the overall flavor experience by interacting with taste perception in the brain.
6. Salivation: The production of saliva, which helps moisten food, making it easier to swallow, and contains enzymes that begin the digestion process.
7. Protective mechanisms: The mouth has several defense mechanisms to protect against harmful bacteria and other pathogens, such as the flow of saliva, which helps wash away food particles, and the presence of antibacterial compounds in saliva.

The digestive system is a complex network of organs and glands that work together to break down food into nutrients, which are then absorbed and utilized by the body for energy, growth, and cell repair. The physiological phenomena associated with the digestive system include:

1. Ingestion: This is the process of taking in food through the mouth.
2. Mechanical digestion: This involves the physical breakdown of food into smaller pieces through processes such as chewing, churning, and segmentation.
3. Chemical digestion: This involves the chemical breakdown of food molecules into simpler forms that can be absorbed by the body. This is achieved through the action of enzymes produced by the mouth, stomach, pancreas, and small intestine.
4. Motility: This refers to the movement of food through the digestive tract, which is achieved through a series of coordinated muscle contractions called peristalsis.
5. Secretion: This involves the production and release of various digestive juices and enzymes by glands such as the salivary glands, gastric glands, pancreas, and liver.
6. Absorption: This is the process of absorbing nutrients from the digested food into the bloodstream through the walls of the small intestine.
7. Defecation: This is the final process of eliminating undigested food and waste products from the body through the rectum and anus.

Overall, the coordinated functioning of these physiological phenomena ensures the proper digestion and absorption of nutrients, maintaining the health and well-being of the individual.

The digestive system is a series of organs and glands that work together to break down food into nutrients, absorb those nutrients into the body, and eliminate waste. The following are the main processes involved in the digestive system:

1. Ingestion: This is the process of taking food into the mouth and chewing it to make it easier to swallow.
2. Mechanical digestion: This involves physically breaking down food into smaller pieces through chewing, churning, and segmentation movements of the muscles in the stomach and intestines.
3. Chemical digestion: This is the process of breaking down food molecules into simpler forms that can be absorbed by the body. This is accomplished by enzymes secreted by various glands, including the salivary glands, stomach, pancreas, and small intestine.
4. Absorption: Once food molecules are broken down into simple forms, they are absorbed into the bloodstream through the walls of the small intestine.
5. Distribution: The absorbed nutrients are then distributed to different cells and tissues throughout the body through the circulatory system.
6. Defecation: This is the process of eliminating waste products from the body through the rectum and anus.

Overall, the digestive system plays a critical role in maintaining health and providing the necessary nutrients for the body to function properly.

A digestive system fistula is an abnormal connection or passageway that forms between the organs of the gastrointestinal tract, such as the stomach, small intestine, colon, or rectum, and another organ, tissue, or the skin. Fistulas can develop as a result of injury, surgery, infection, inflammation, or cancer.

In the digestive system, fistulas can cause symptoms such as abdominal pain, diarrhea, fever, nausea, vomiting, and malnutrition. The severity of these symptoms depends on the location and size of the fistula, as well as the underlying cause. Treatment for a digestive system fistula may involve antibiotics to treat infection, nutritional support, and surgical repair of the fistula.

The gastrointestinal (GI) tract, also known as the digestive tract, is a continuous tube that starts at the mouth and ends at the anus. It is responsible for ingesting, digesting, absorbing, and excreting food and waste materials. The GI tract includes the mouth, esophagus, stomach, small intestine (duodenum, jejunum, ileum), large intestine (cecum, colon, rectum, anus), and accessory organs such as the liver, gallbladder, and pancreas. The primary function of this system is to process and extract nutrients from food while also protecting the body from harmful substances, pathogens, and toxins.

Clemastine is an antihistamine medication that is used to relieve symptoms of allergies, such as runny nose, sneezing, and itchy or watery eyes. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Clemastine is available in oral tablet and liquid forms, and is typically taken twice daily with a full glass of water.

Common side effects of clemastine include drowsiness, dry mouth, headache, and upset stomach. It is important to avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you. Clemastine may also cause dizziness, so it is best to avoid getting up too quickly from a sitting or lying position.

Like all medications, clemastine should be taken only as directed by your healthcare provider. It is important to inform them of any other medications you are taking, as well as any medical conditions you may have, as clemastine can interact with certain drugs and may not be suitable for everyone.

Gastrointestinal (GI) neoplasms refer to abnormal growths in the gastrointestinal tract, which can be benign or malignant. The gastrointestinal tract includes the mouth, esophagus, stomach, small intestine, large intestine, rectum, and anus.

Benign neoplasms are non-cancerous growths that do not invade nearby tissues or spread to other parts of the body. They can sometimes be removed completely and may not cause any further health problems.

Malignant neoplasms, on the other hand, are cancerous growths that can invade nearby tissues and organs and spread to other parts of the body through the bloodstream or lymphatic system. These types of neoplasms can be life-threatening if not diagnosed and treated promptly.

GI neoplasms can cause various symptoms, including abdominal pain, bloating, changes in bowel habits, nausea, vomiting, weight loss, and anemia. The specific symptoms may depend on the location and size of the neoplasm.

There are many types of GI neoplasms, including adenocarcinomas, gastrointestinal stromal tumors (GISTs), lymphomas, and neuroendocrine tumors. The diagnosis of GI neoplasms typically involves a combination of medical history, physical examination, imaging studies, and biopsy. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or immunotherapy.

Central nervous system (CNS) neoplasms refer to a group of abnormal growths or tumors that develop within the brain or spinal cord. These tumors can be benign or malignant, and their growth can compress or disrupt the normal functioning of surrounding brain or spinal cord tissue.

Benign CNS neoplasms are slow-growing and rarely spread to other parts of the body. However, they can still cause significant problems if they grow large enough to put pressure on vital structures within the brain or spinal cord. Malignant CNS neoplasms, on the other hand, are aggressive tumors that can invade and destroy surrounding tissue. They may also spread to other parts of the CNS or, rarely, to other organs in the body.

CNS neoplasms can arise from various types of cells within the brain or spinal cord, including nerve cells, glial cells (which provide support and insulation for nerve cells), and supportive tissues such as blood vessels. The specific type of CNS neoplasm is often used to help guide treatment decisions and determine prognosis.

Symptoms of CNS neoplasms can vary widely depending on the location and size of the tumor, but may include headaches, seizures, weakness or paralysis, vision or hearing changes, balance problems, memory loss, and changes in behavior or personality. Treatment options for CNS neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

The digestive system is a complex series of organs and glands that process food. Abnormalities in the digestive system can refer to a wide range of conditions that affect any part of the system, including the esophagus, stomach, small intestine, large intestine, liver, pancreas, and gallbladder. These abnormalities can be present at birth (congenital) or acquired later in life due to various factors such as infection, inflammation, injury, or disease.

Some examples of digestive system abnormalities include:

1. Gastroesophageal Reflux Disease (GERD): A condition where the stomach acid flows back into the esophagus, causing heartburn and damage to the esophageal lining.
2. Peptic Ulcers: Open sores that develop on the lining of the stomach or duodenum, often caused by bacterial infections or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
3. Inflammatory Bowel Disease (IBD): A group of chronic inflammatory conditions of the intestine, including Crohn's disease and ulcerative colitis.
4. Irritable Bowel Syndrome (IBS): A functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits.
5. Celiac Disease: An autoimmune disorder where the ingestion of gluten leads to damage in the small intestine.
6. Diverticulosis: The presence of small pouches or sacs that form on the lining of the intestine, which can become inflamed or infected (diverticulitis).
7. Hiatal Hernia: A condition where a portion of the stomach protrudes through the diaphragm into the chest cavity.
8. Hepatitis: Inflammation of the liver, often caused by viral infections or toxins.
9. Cirrhosis: A chronic liver disease characterized by scarring and loss of liver function, often due to long-term alcohol abuse or hepatitis.
10. Gallstones: Small, hard deposits that form in the gallbladder and can cause pain and inflammation.

These are just a few examples of gastrointestinal disorders, and there are many others. If you are experiencing symptoms such as abdominal pain, bloating, diarrhea, constipation, or difficulty swallowing, it is important to speak with your healthcare provider to determine the cause and develop an appropriate treatment plan.

Diagnostic techniques for the digestive system are medical tests and procedures used to diagnose and evaluate various conditions and diseases related to the gastrointestinal (GI) tract, including the esophagus, stomach, small intestine, large intestine, liver, gallbladder, pancreas, and associated organs. These techniques can be categorized into invasive and non-invasive methods.

Non-invasive diagnostic techniques:

1. Imaging tests: These include X-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), positron emission tomography (PET) scans, and ultrasounds. They help visualize the structure and function of the digestive organs without requiring any invasive procedures.
2. Laboratory tests: Blood, stool, and urine samples can be analyzed to detect signs of infection, inflammation, or other abnormalities related to digestive system disorders. Examples include complete blood count (CBC), liver function tests (LFTs), coagulation studies, and fecal occult blood test (FOBT).
3. Breath tests: These are used to diagnose conditions like lactose intolerance, small intestinal bacterial overgrowth (SIBO), or helicobacter pylori infection by analyzing the patient's exhaled air after consuming a specific substance.

Invasive diagnostic techniques:

1. Endoscopy: A thin, flexible tube with a light and camera attached to its end is inserted through the mouth or rectum to directly visualize the GI tract's inner lining. There are different types of endoscopies, such as gastroscopy (esophagus, stomach, and duodenum), colonoscopy (colon and rectum), sigmoidoscopy (lower part of the colon), and enteroscopy (small intestine).
2. Endoscopic ultrasound (EUS): This combines endoscopy with ultrasound technology to provide detailed images of the digestive organs' structure and surrounding tissues, allowing for accurate diagnosis and staging of conditions like cancer.
3. Biopsy: During an endoscopy or surgery, a small tissue sample can be taken from the affected area for further examination under a microscope to confirm a diagnosis or assess the severity of a condition.
4. Capsule endoscopy: A patient swallows a tiny camera-equipped capsule that transmits images as it passes through the GI tract, allowing doctors to diagnose conditions in the small intestine that may be difficult to reach with traditional endoscopes.
5. Imaging studies: Procedures like computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET) scans can provide detailed images of the digestive organs and help diagnose conditions like tumors, inflammation, or obstructions.

These diagnostic techniques help healthcare providers identify and manage various gastrointestinal conditions, ensuring appropriate treatment and improved patient outcomes.

Gastrointestinal diseases refer to a group of conditions that affect the gastrointestinal (GI) tract, which includes the organs from the mouth to the anus, responsible for food digestion, absorption, and elimination of waste. These diseases can affect any part of the GI tract, causing various symptoms such as abdominal pain, bloating, diarrhea, constipation, nausea, vomiting, and weight loss.

Common gastrointestinal diseases include:

1. Gastroesophageal reflux disease (GERD) - a condition where stomach acid flows back into the esophagus, causing heartburn and other symptoms.
2. Peptic ulcers - sores that develop in the lining of the stomach or duodenum, often caused by bacterial infection or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
3. Inflammatory bowel disease (IBD) - a group of chronic inflammatory conditions of the intestine, including Crohn's disease and ulcerative colitis.
4. Irritable bowel syndrome (IBS) - a functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits.
5. Celiac disease - an autoimmune disorder where the ingestion of gluten leads to damage in the small intestine.
6. Diverticular disease - a condition that affects the colon, causing diverticula (small pouches) to form and potentially become inflamed or infected.
7. Constipation - a common gastrointestinal symptom characterized by infrequent bowel movements, hard stools, and difficulty passing stools.
8. Diarrhea - a common gastrointestinal symptom characterized by loose, watery stools and frequent bowel movements.
9. Food intolerances and allergies - adverse reactions to specific foods or food components that can cause various gastrointestinal symptoms.
10. Gastrointestinal infections - caused by bacteria, viruses, parasites, or fungi that can lead to a range of symptoms, including diarrhea, vomiting, and abdominal pain.

The pancreas is a glandular organ located in the abdomen, posterior to the stomach. It has both exocrine and endocrine functions. The exocrine portion of the pancreas consists of acinar cells that produce and secrete digestive enzymes into the duodenum via the pancreatic duct. These enzymes help in the breakdown of proteins, carbohydrates, and fats in food.

The endocrine portion of the pancreas consists of clusters of cells called islets of Langerhans, which include alpha, beta, delta, and F cells. These cells produce and secrete hormones directly into the bloodstream, including insulin, glucagon, somatostatin, and pancreatic polypeptide. Insulin and glucagon are critical regulators of blood sugar levels, with insulin promoting glucose uptake and storage in tissues and glucagon stimulating glycogenolysis and gluconeogenesis to raise blood glucose when it is low.

The intestines, also known as the bowel, are a part of the digestive system that extends from the stomach to the anus. They are responsible for the further breakdown and absorption of nutrients from food, as well as the elimination of waste products. The intestines can be divided into two main sections: the small intestine and the large intestine.

The small intestine is a long, coiled tube that measures about 20 feet in length and is lined with tiny finger-like projections called villi, which increase its surface area and enhance nutrient absorption. The small intestine is where most of the digestion and absorption of nutrients takes place.

The large intestine, also known as the colon, is a wider tube that measures about 5 feet in length and is responsible for absorbing water and electrolytes from digested food, forming stool, and eliminating waste products from the body. The large intestine includes several regions, including the cecum, colon, rectum, and anus.

Together, the intestines play a critical role in maintaining overall health and well-being by ensuring that the body receives the nutrients it needs to function properly.

Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.

Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.

Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.

In anatomical terms, the stomach is a muscular, J-shaped organ located in the upper left portion of the abdomen. It is part of the gastrointestinal tract and plays a crucial role in digestion. The stomach's primary functions include storing food, mixing it with digestive enzymes and hydrochloric acid to break down proteins, and slowly emptying the partially digested food into the small intestine for further absorption of nutrients.

The stomach is divided into several regions, including the cardia (the area nearest the esophagus), the fundus (the upper portion on the left side), the body (the main central part), and the pylorus (the narrowed region leading to the small intestine). The inner lining of the stomach, called the mucosa, is protected by a layer of mucus that prevents the digestive juices from damaging the stomach tissue itself.

In medical contexts, various conditions can affect the stomach, such as gastritis (inflammation of the stomach lining), peptic ulcers (sores in the stomach or duodenum), gastroesophageal reflux disease (GERD), and stomach cancer. Symptoms related to the stomach may include abdominal pain, bloating, nausea, vomiting, heartburn, and difficulty swallowing.

A larva is a distinct stage in the life cycle of various insects, mites, and other arthropods during which they undergo significant metamorphosis before becoming adults. In a medical context, larvae are known for their role in certain parasitic infections. Specifically, some helminth (parasitic worm) species use larval forms to infect human hosts. These invasions may lead to conditions such as cutaneous larva migrans, visceral larva migrans, or gnathostomiasis, depending on the specific parasite involved and the location of the infection within the body.

The larval stage is characterized by its markedly different morphology and behavior compared to the adult form. Larvae often have a distinct appearance, featuring unsegmented bodies, simple sense organs, and undeveloped digestive systems. They are typically adapted for a specific mode of life, such as free-living or parasitic existence, and rely on external sources of nutrition for their development.

In the context of helminth infections, larvae may be transmitted to humans through various routes, including ingestion of contaminated food or water, direct skin contact with infective stages, or transmission via an intermediate host (such as a vector). Once inside the human body, these parasitic larvae can cause tissue damage and provoke immune responses, leading to the clinical manifestations of disease.

It is essential to distinguish between the medical definition of 'larva' and its broader usage in biology and zoology. In those fields, 'larva' refers to any juvenile form that undergoes metamorphosis before reaching adulthood, regardless of whether it is parasitic or not.

Tissue distribution, in the context of pharmacology and toxicology, refers to the way that a drug or xenobiotic (a chemical substance found within an organism that is not naturally produced by or expected to be present within that organism) is distributed throughout the body's tissues after administration. It describes how much of the drug or xenobiotic can be found in various tissues and organs, and is influenced by factors such as blood flow, lipid solubility, protein binding, and the permeability of cell membranes. Understanding tissue distribution is important for predicting the potential effects of a drug or toxin on different parts of the body, and for designing drugs with improved safety and efficacy profiles.

Liver neoplasms refer to abnormal growths in the liver that can be benign or malignant. Benign liver neoplasms are non-cancerous tumors that do not spread to other parts of the body, while malignant liver neoplasms are cancerous tumors that can invade and destroy surrounding tissue and spread to other organs.

Liver neoplasms can be primary, meaning they originate in the liver, or secondary, meaning they have metastasized (spread) to the liver from another part of the body. Primary liver neoplasms can be further classified into different types based on their cell of origin and behavior, including hepatocellular carcinoma, cholangiocarcinoma, and hepatic hemangioma.

The diagnosis of liver neoplasms typically involves a combination of imaging studies, such as ultrasound, CT scan, or MRI, and biopsy to confirm the type and stage of the tumor. Treatment options depend on the type and extent of the neoplasm and may include surgery, radiation therapy, chemotherapy, or liver transplantation.

Stomach neoplasms refer to abnormal growths in the stomach that can be benign or malignant. They include a wide range of conditions such as:

1. Gastric adenomas: These are benign tumors that develop from glandular cells in the stomach lining.
2. Gastrointestinal stromal tumors (GISTs): These are rare tumors that can be found in the stomach and other parts of the digestive tract. They originate from the stem cells in the wall of the digestive tract.
3. Leiomyomas: These are benign tumors that develop from smooth muscle cells in the stomach wall.
4. Lipomas: These are benign tumors that develop from fat cells in the stomach wall.
5. Neuroendocrine tumors (NETs): These are tumors that develop from the neuroendocrine cells in the stomach lining. They can be benign or malignant.
6. Gastric carcinomas: These are malignant tumors that develop from the glandular cells in the stomach lining. They are the most common type of stomach neoplasm and include adenocarcinomas, signet ring cell carcinomas, and others.
7. Lymphomas: These are malignant tumors that develop from the immune cells in the stomach wall.

Stomach neoplasms can cause various symptoms such as abdominal pain, nausea, vomiting, weight loss, and difficulty swallowing. The diagnosis of stomach neoplasms usually involves a combination of imaging tests, endoscopy, and biopsy. Treatment options depend on the type and stage of the neoplasm and may include surgery, chemotherapy, radiation therapy, or targeted therapy.

Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.

Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.

Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.

There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.

The "cause of death" is a medical determination of the disease, injury, or event that directly results in a person's death. This information is typically documented on a death certificate and may be used for public health surveillance, research, and legal purposes. The cause of death is usually determined by a physician based on their clinical judgment and any available medical evidence, such as laboratory test results, autopsy findings, or eyewitness accounts. In some cases, the cause of death may be uncertain or unknown, and the death may be classified as "natural," "accidental," "homicide," or "suicide" based on the available information.

Digestive system neoplasms are tumors which affect the digestive system. There are many different and various pathologic ... classification for digestive system neoplasms. Considering the part of the digestive system that they origin, they are ... Emerging findings indicate that bile acids have a carcinogenic role throughout the digestive system. Excessive exposure of ... "Viruses in Cancers of the Digestive System: Active Contributors or Idle Bystanders?". International Journal of Molecular ...
Progress in surgical techniques in digestive system neoplasms. 2013; -Gong Ji Surgery Forum; OCT 27, 2013; Shanghai, CHINA. S. ... Early experience with telemanipulative abdominal and cardiac surgery with the Zeus robotic system. In: European Surgery (ACA). ...
C06 for Digestive System Diseases and C06.301 for Digestive System Neoplasms; C04 for Neoplasms, C04.588 for Neoplasms By Site ... For example, the descriptor "Digestive System Neoplasms" has the tree numbers C06.301 and C04.588.274; C stands for Diseases, ... and C04.588.274 also for Digestive System Neoplasms. The tree numbers of a given descriptor are subject to change as MeSH is ...
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... and grading of neuroendocrine neoplasms arising in the digestive system". UpToDate. This topic last updated: Oct 29, 2019. Amin ... Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine (hormonal) and nervous systems. They most ... 2010). WHO Classification of Tumours of the Digestive System (4 ed.). Lyon: International Agency for Research on Cancer. pp. 13 ... Currently there is no one staging system for all neuroendocrine neoplasms. Well-differentiated lesions generally have their own ...
December 2021). "Volatile organic compounds as a potential screening tool for neoplasm of the digestive system: a meta-analysis ... The TNM staging system is also used. In a study of open-access endoscopy in Scotland, patients were diagnosed 7% in stage I, 17 ... The GLOBOCAN system is currently the most widely used method to compare these rates between countries, but African incidence ... The stomach is a muscular organ of the gastrointestinal tract that holds food and begins the digestive process by secreting ...
In Australia, the main hospital separations of 2004-05 were: Digestive system problems. Neoplasms. Injury/Poisoning. Pregnancy/ ... Circulatory system diseases. Neoplasms. Injury/Poisoning. "Discharges". Meteor Australian Institute of Health and Welfare. ...
Tumours of the pancreas: Pancreatic mucinous cystic neoplasm". Digestive System Tumours. Vol. 1 (5th ed.). Lyon (France). pp. ...
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... neoplasm of lymph nodes 197 Secondary malignant neoplasm of respiratory and digestive systems 198 Secondary malignant neoplasm ... in situ of other and unspecified sites 235 Neoplasm of uncertain behavior of digestive and respiratory systems 236 Neoplasm of ... pharynx 211 Benign neoplasm of other parts of digestive system 211.3 Colon Familial adenomatous polyposis 212 Benign neoplasm ... 140 Malignant neoplasm of lip 141 Malignant neoplasm of tongue 142 Malignant neoplasm of major salivary glands 143 Malignant ...
The major causes of death are diseases of the circulatory system, neoplasms, diseases of respiratory system and accidents and ... digestive system and circulation system. Infectious diseases are still the source of significant health problems, especially ... From 1921 to 1991, the Georgian health system was part of the Soviet system. Till 1995 health care system in Georgia was based ... "Georgia: Health system review." Health Systems in Transition. World Bank Group. 2017. Georgia Public Expenditure Review "Life ...
Tumours of the pancreas: Pancreatic serous cystadenoma". Digestive System Tumours. Vol. 1 (5th ed.). Lyon (France). pp. 303-306 ... mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because ... Serous cystic neoplasms that have spread ("metastasized") to another organ are considered malignant and are designated "serous ... In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and ...
As of 2018, the leading cause of death were diseases of cardiovascular system with 52,663 (51.8%) deaths, followed by neoplasms ... diseases of the digestive system with 3,204 (3.2%) deaths. As of 2018, a total of 2,806 people died by violence, of which 2,065 ... Other causes of death were diseases of respiratory system with 5,250 (5.2%) deaths, group of endocrine, nutritional and ...
Used to explore the immune system and genetic strains. They are low in cost, small size, fast reproduction rate, and able to ... The National Library of Medicine also explains how a neoplasm is difficult to diagnose at an early stage. Understanding the ... molecular mechanism of digestive tract tumorigenesis and searching for new treatments is the current research. Zebrafish and ... However, the lack of an adaptive immune system and their simple organs prevent worms from being used in several aspects of ...
... is highly resistant to digestive acids if ingested. Cats regularly ingest hair as part of their grooming behavior, ... Tumors that express keratin include carcinomas, thymomas, sarcomas and trophoblastic neoplasms. Furthermore, the precise ... List of cutaneous conditions caused by mutations in keratins List of keratins expressed in the human integumentary system List ...
Digestive system, Symptoms and signs: Digestive system and abdomen, Sounds by type, Abdomen). ... Some examples of diseases that may be associated with this symptom include carcinoid neoplasm and coeliac sprue. Louder rumbles ... Around two hours after the stomach has been emptied, it sends signals to the brain, which tells the digestive muscles to ... In rare instances, excessive abdominal noise may be a sign of digestive disease, especially when accompanied by abdominal ...
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... s may be used to investigate symptoms in the digestive system including nausea, vomiting, abdominal pain, difficulty ... Small intestine: small intestine neoplasms, smooth muscle tumors, sarcomas, polyps, lymphomas, inflammation, etc. Large ... A lens system that transmits the image from the objective lens to the observer, usually a relay lens system in the case of a ... and cancers of the digestive system. The procedure may also be used for treatment such as cauterization of a bleeding vessel, ...
Sung JY, Costerton JW, Shaffer EA (May 1992). "Defense system in the biliary tract against bacterial infection". Digestive ... Gore RM, Shelhamer RP (October 2007). "Biliary tract neoplasms: diagnosis and staging". Cancer Imaging. 7 Spec No A (Special ... Gallstone disease is considered to be one of the most common digestive diseases. It is prevalent regardless of ethnicity with ... "Definition & Facts for Gallstones , NIDDK". National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 2020-04 ...
... diseases of the digestive system List of ICD-9 codes 580-629: diseases of the genitourinary system List of ICD-9 codes 630-679 ... List of ICD-9 codes 001-139: infectious and parasitic diseases List of ICD-9 codes 140-239: neoplasms List of ICD-9 codes 240- ... diseases of the nervous system and sense organs List of ICD-9 codes 390-459: diseases of the circulatory system List of ICD-9 ... diseases of the musculoskeletal system and connective tissue List of ICD-9 codes 740-759: congenital anomalies List of ICD-9 ...
Diseases of the respiratory system 799-869.........................................Diseases of the digestive system. ... Neoplasms. Tumors. Oncology 680-688...................................Diseases of the locomotor system (Surgical treatment) 701 ... Class R:Medicine is a classification used by the Library of Congress Classification system. This page outlines the subclasses ... Diseases of the nervous system Including speech disorders 435-571...............................................Psychiatry 475- ...
Tumours of the pancreas". Digestive System Tumours. Vol. 1 (5th ed.). Lyon (France). pp. 295-372. ISBN 978-92-832-4499-8.{{cite ... The last type of exocrine tumors include pancreatic mucinous cystic neoplasms, which have fluid filled cavities. These types of ... which implies that they begin within the part of the pancreas responsible for creating digestive enzymes. Different subtypes of ...
Both surgery and advanced inoperable tumors often lead to digestive system disorders from a lack of the exocrine products of ... Pancreatic mucinous cystic neoplasms are a broad group of pancreas tumors that have varying malignant potential. They are being ... The 2010 WHO classification of tumors of the digestive system grades all the pancreatic neuroendocrine tumors (PanNETs) into ... A different TNM system for PanNETs has been proposed by the European Neuroendocrine Tumor Society. Apart from not smoking, the ...
Lymphomas are malignant neoplasms (cancers) arising from lymphocytes of the immune system. When they arise in the bowel tissue ... American Journal of Digestive Diseases. 6 (11): 1084-1114. doi:10.1007/BF02231137. PMID 14470233. S2CID 30610401. Marshak; et ...
Undigested objects such as seeds can pass through the human digestive system, and later germinate. One result of this is tomato ... ulcerative colitis and neoplasms (cancer). Also, feces may be analyzed for any fecal occult blood, which is indicative of a ... digestive system and general health. Normally human feces is semisolid, with a mucus coating. Small pieces of harder, less ... either from lower in the digestive tract, or from a more active source in the upper digestive tract. Alcoholism can also ...
Digestive system - The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion ( ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Circulatory system - The circulatory system, also called the cardiovascular system or the vascular system, is an organ system ... Genitourinary system - The genitourinary system, or urogenital system, are the organs of the reproductive system and the ...
Embryology of digestive system). ... Craniopharyngioma is a neoplasm which can arise from the ... It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system. Rathke's pouch, and therefore the ... Embryology at UNSW wwwhuman/hipower/HumB/b2l Histology image: 14101loa - Histology Learning System at Boston University Diagram ...
The new 2019 WHO classification and grading criteria for neuroendocrine tumors of the digestive system grades all the ... are neuroendocrine neoplasms that arise from cells of the endocrine (hormonal) and nervous system within the pancreas. PanNETs ... "The 2019 WHO classification of tumours of the digestive system". Histopathology. 76 (2): 182-188. doi:10.1111/his.13975. ISSN ... A different TNM system for PanNETs has been proposed by The European Neuroendocrine Tumor Society. Pancreatic neuroendocrine ...
Digestive system neoplasms are tumors which affect the digestive system. There are many different and various pathologic ... classification for digestive system neoplasms. Considering the part of the digestive system that they origin, they are ... Emerging findings indicate that bile acids have a carcinogenic role throughout the digestive system. Excessive exposure of ... "Viruses in Cancers of the Digestive System: Active Contributors or Idle Bystanders?". International Journal of Molecular ...
"Digestive System Neoplasms" by people in this website by year, and whether "Digestive System Neoplasms" was a major or minor ... "Digestive System Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Digestive System Neoplasms*Digestive System Neoplasms. *Digestive System Neoplasm. *Neoplasm, Digestive System ... Below are the most recent publications written about "Digestive System Neoplasms" by people in Profiles. ...
Retrieved from "https://ccmdb.kuality.ca/index.php?title=Digestive_system_NOS,_benign_neoplasm&oldid=143783" ... Mouth or pharynx or salivary glands, benign neoplasm ‎ (← links). *Colon (large intestine) or rectum or anus, benign neoplasm ... Endocrine neoplasm, Exposure, Eye, Female genital neoplasm, Fistula, Fracture, Fungus, GI ulcer, Gastroenteritis, ... Pancreas, benign neoplasm ‎ (← links). *Multiple endocrine adenomatosis (multiple endocrine neoplasia syndrome, MEN) ‎ (← links ...
Aims: Criteria for the interpretation of digestive system neuroendocrine neoplasms (NENs) continue to evolve. Although there ... Aims: Criteria for the interpretation of digestive system neuroendocrine neoplasms (NENs) continue to evolve. Although there ... Practice patterns for reporting digestive system neuroendocrine neoplasms: results from a large, comprehensive international ... This survey highlights current key grey areas in digestive system NEN evaluation, leading to variation in practice patterns. ...
Most pancreatic endocrine neoplasms discovered clinically are functional; ie, they secrete one or more hormonal products into ... Neoplasms of the endocrine pancreas can be divided into functional and nonfunctional varieties. ... Neoplasms of the Digestive System. 1998. Lippincott Raven:. *. Krausz Y, Bar-Ziv J, de Jong RB, et al. Somatostatin-receptor ... Neoplasms of the gastroenteropancreatic endocrine system. In: Holland JF, Frei E, Bast RC, eds. Cancer Medicine. Philadelphia, ...
Digestive System Neoplasms / complications* * Humans * Inflammatory Bowel Diseases / complications ...
RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.在哪里下载?这篇文献 ... RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.. Abstract ... RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system. ... Next-generation narrow band imaging system for colonic polyp detection: a prospective multicenter randomized trial. abstract: ...
Benign Neoplasm of the Digestive System. *Bruise of Face, Scalp, or Neck ... STELARA® may decrease the activity of your immune system and increase your risk for certain types of cancer. Tell your doctor ... STELARA® is a prescription medicine that affects your immune system. STELARA® can increase your chance of having serious side ... The viruses used in some types of live vaccines can spread to people with a weakened immune system, and can cause serious ...
Benign Neoplasm of the Digestive System. *Cancer. *Cholecystitis. *Cholecystitis and Gallstones. *Chronic Appendicitis ...
Categories: Digestive System Neoplasms Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Digestive System Neoplasms. Carcinoma, Neuroendocrine. Endocrine Gland Neoplasms. Neoplasms, Thoracic. Gastrointestinal ... Lymphedema Melanoma Merkel Cell Carcinoma Mesothelioma Multiple Myeloma Myelodysplastic Syndrome Myeloproliferative Neoplasms ...
Benign Neoplasm of the Digestive System ... View other providers who treat Benign Neoplasm of the Digestive ... healthDigestive healthSkin healthExercise and fitnessSleep disordersHeart healthTransgender healthHepatitis CType 2 diabetes ... healthDigestive healthSkin healthExercise and fitnessSleep disordersHeart healthTransgender healthHepatitis CType 2 diabetes ... and nutritionDigestive healthEndometriosisEczemaExercise and fitnessFibromyalgiaHeart attackHeart healthHepatitis CHypertension ...
Overview of dental conditions related to neoplasms and the digestive system *Introduction to CPT®, HCPCS Level II, and ... High-speed Internet access with supported computer operating systems and Internet/Web browsers ...
Benign Neoplasm of the Digestive System ... View other providers who treat Benign Neoplasm of the Digestive ... healthDigestive healthSkin healthExercise and fitnessSleep disordersHeart healthTransgender healthHepatitis CType 2 diabetes ... healthDigestive healthSkin healthExercise and fitnessSleep disordersHeart healthTransgender healthHepatitis CType 2 diabetes ... and nutritionDigestive healthEndometriosisEczemaExercise and fitnessFibromyalgiaHeart attackHeart healthHepatitis CHypertension ...
Learn about Pancreatic Neuroendocrine Neoplasms (pNENs), including symptoms, causes, and treatments. If you or a loved one is ... ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms of the digestive system: well ... Related Rare Diseases: Perivascular Epithelioid Cell Neoplasm, Acute Promyelocytic Leukemia, Primary Central Nervous System ... Pancreatic Neuroendocrine Neoplasms (pNENs). Print Last updated: January 04, 2017 Years published: 1990, 2000, 2011, 2014, 2017 ...
Benign neoplasm of endocrine pancreas D13.9 Benign neoplasm of ill-defined sites within the digestive system ... we instruct contractors and system maintainers to modify the claims processing systems at the national or local level through ... CRs are not policy, rather CRs are used to relay instructions regarding the edits of the various claims processing systems in ... Malignant neoplasm of intestinal tract, part unspecified D13.7 ... As clinical or administrative codes change or system or policy ...
pancreatic neoplasms. digestive system neoplasms. pancreatic diseases. digestive system diseases. pancreatic adenocarcinoma. ... Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Paclitaxel. Antineoplastic Agents, Phytogenic. ...
Association Between Anti-bacterial Drug Use and Digestive System Neoplasms: A Systematic Review and Meta-analysis ...
Nomenclature and classification of neuroendocrine neoplasms of the digestive system; in Bosman FT, Carniero F, Hruban RH, ... Anlauf M: Neuroendocrine neoplasms of the gastroenteropancreatic system: pathology and classification. Horm Metab Res 2011;43: ... Theise ND (eds): WHO Classification of Tumours of the Digestive System, ed 4. Lyon, IARC, 2010, pp 13-14. ... Around 25% of the NETs are localized in the bronchopulmonary system. Approximately 2% of all lung tumors are NETs. According to ...
Information about the SNOMED CT code 95089001 representing Neoplasm of uncertain behavior of soft palate. ... Mass of digestive structure 300855001. Neoplasm of digestive system 128348002. Neoplasm of digestive tract 128415001. Neoplasm ... Neoplasm of digestive system 128348002. Neoplasm of digestive tract 128415001. Neoplasm of soft palate 126807001. Neoplasm of ... Neoplasm of head 126631009. Neoplasm of palate 126805009. Neoplasm of uncertain behavior of palate 94975000. Neoplasm of ...
Additions D13.91 Familial adenomatous polyposis D13.99 Benign neoplasm of ill-defined sites within the digestive system [ ... Deletion: D13.9 Benign neoplasm of ill-defined sites within the digestive system] D48.110 Desmoid tumor of head and neck ... Diseases of the Digestive System ICD-10-CM Code Additions, Deletions, and Revisions ... Diseases of the Digestive System ICD-10-CM Code Additions, Deletions, and Revisions ...
Digestive System Neoplasms, Hernia, Inguinal, Esophageal Neoplasms, Crohn Disease, General Surgery ... Colorectal Surgery, Anus Neoplasms, Diverticulum, Video-Assisted Surgery, Inflammatory Bowel Diseases, ...
Deaths from other malignant neoplasms (digestive system, genitourinary, lymphatic, and hematopoietic tissue) were lower (non- ... as shown by increased incidences of alveolar/bronchiolar neoplasms and of hepatocellular neoplasms" (NTP 1986). ... based on increased incidences of alveolar/bronchiolar neoplasms (adenomas, carcinomas) and of hepatocellular neoplasms ( ... Integumentary system tumours "in the area of the mammary chain" occurred with a positive trend in males (subcutaneous tissue ...
Digestive System Neoplasms [C04.588.274]. *Gastrointestinal Neoplasms [C04.588.274.476]. *Intestinal Neoplasms [C04.588.274.476 ... "Sigmoid Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Sigmoid Neoplasms" by people in UAMS Profiles by year, and ... Below are the most recent publications written about "Sigmoid Neoplasms" by people in Profiles over the past ten years. ...
... neoplasms; certain infectious and parasitic diseases; diseases of the digestive system; and mental and behavior disorders ( ... diseases of the digestive system (RR 1.3, 95% CI 1.1-1.5); and diseases of the musculoskeletal system and connective tissue (RR ... neoplasms (RR 4.9, 95% CI 4.4-5.5); mental and behavior disorders (RR 3.1, 95% CI 2.4-4.1); diseases of the circulatory system ... and other parts of the central nervous system (CNS); respiratory and intrathoracic organs; digestive organs; breast; male and ...
Applications of Artificial Intelligence in Digestive System Neoplasms. Amino: A Web3 Sports, Health, and Fitness Ecosystem. ...
Digestive-system; Respiratory-system-disorders; Malignant-neoplasms; Mesothelial-cells; Asbestos-fibers ... comprised mainly of digestive (SMR=1.26, 95% CI 1.18 to 1.34, n=928; SIR=1.17, 95% CI 1.10 to 1.25, n=930) and respiratory (SMR ...
Pancreatic cancer is an insidious and rapidly progressing digestive system neoplasm. It ranks second among the causes of ... digestive system cancer-related death [1]. Pancreatic ductal adenocarcinoma (PDAC) is the most common pathological type, and ... Anatomic neoplasm subdivision. Head of pancreas. 145. 78.80. 106. 82.17. 39. 70.91. ... and Groupe Tumeurs Digestives of Unicancer, and PRODIGE Intergroup. FOLFIRINOX versus gemcitabine for metastatic pancreatic ...
Method 2, adjusted for age; diseases of the respiratory, digestive, circulatory, and genitourinary systems; endocrine diseases ... neoplasms and other diseases; history of admissions and antimicrobial drug use in the prior 3 mos. Method 3, adjusted for age; ...
  • His current research interests are related with the carcinogenesis and neoplasms of the digestive system, with a primary focus on colorectal neoplasms. (bjbms.org)
  • Digestive system neoplasms are tumors which affect the digestive system. (wikipedia.org)
  • Tumors or cancer of the DIGESTIVE SYSTEM. (rush.edu)
  • Patients with pancreatic neoplasms that have the histologic characteristics of a pancreatic endocrine tumor but no associated elevation in plasma hormone levels (excluding the pancreatic polypeptide level) and those without a recognizable clinical syndrome are considered to have nonfunctional pancreatic endocrine tumors. (medscape.com)
  • Although the term islet cell tumor is often used to identify neoplasms of the endocrine pancreas, this is a misnomer because many pancreatic neuroendocrine tumors do not develop directly from islet cells. (medscape.com)
  • Functional pancreatic endocrine neoplasms cause physiologic derangements related to the normal action of the hormonal product that the tumors overproduce. (medscape.com)
  • Neuroendocrine Tumors of the Bronchopulmonary System (Typical and Atypical Carcinoid Tumors): Current Strategies in Diagnosis and Treatment. (karger.com)
  • Gallbladder Cancer: A Single-Institution 10-Year Experience-Analysis of Adenocarcinoma Subtypes and Tumors Arising from Intracholecystic Papillary Neoplasms. (ouhsc.edu)
  • Neoplasms originating from the blood or bone marrow (leukemias and myeloproliferative disorders) are not considered solid tumors. (mycancergenome.org)
  • It is well documented that exposure to asbestos is strongly associated with malignant and nonmalignant respiratory diseases, including asbestosis, mesothelioma, and lung cancer, and to a lesser extent, with digestive cancers (ATSDR 2001). (cdc.gov)
  • 6. Previous history of demyelinating or inflammatory diseases of the central (CNS) or peripheral (PNS) nervous system. (who.int)
  • Because of its partnership with the Veterans Administration Northern California Health Care System, the HLVC provides one-stop care for patients with diseases of the heart, lungs and circulation. (health.mil)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • A benign or malignant neoplasm arising from tissues that do not include fluid areas. (mycancergenome.org)
  • Representative examples include epithelial neoplasms (e.g. lung carcinoma, prostate carcinoma, breast carcinoma, colon carcinoma), and neoplasms arising from the soft tissues and bones (e.g. leiomyosarcoma, liposarcoma, chondrosarcoma, osteosarcoma). (mycancergenome.org)
  • Most pancreatic endocrine neoplasms discovered clinically are functional-that is, they secrete one or more hormonal products into the blood, which leads to a recognizable clinical syndrome. (medscape.com)
  • Several other rare clinical syndromes have been proposed as possible functional endocrine syndromes associated with pancreatic neoplasms. (medscape.com)
  • A subset of these patients have neoplasms that secrete pancreatic polypeptide (ie, PPomas). (medscape.com)
  • The cells in pancreatic endocrine neoplasms are termed amine precursor uptake and decarboxylation (APUD) cells because they have a high amine content, are capable of amine precursor uptake, and contain an amino acid decarboxylase. (medscape.com)
  • [ 16 ] The fact that many gastrinomas and somatostatinomas are found close to, but not within, the pancreatic parenchyma supports the notion of the possible extrapancreatic development of these neoplasms. (medscape.com)
  • Pancreatic neuroendocrine neoplasms (pNENs) are an increasingly common group of malignancies that arise within the endocrine tissue of the pancreas. (rarediseases.org)
  • Pancreatic cancer is an insidious and rapidly progressing digestive system neoplasm. (aging-us.com)
  • Though cystic pancreatic neoplasms (CPNs) are being increasingly detected, their evaluation and management are still debated and have lead to publication of multiple guidelines for diagnostic work-up, indications for resection, and non-operative management with follow-up strategies of CPNs. (nih.gov)
  • Nonfunctioning neuroendocrine neoplasms can still cause symptoms relating to tumor size and location such as obstruction or internal bleeding. (rarediseases.org)
  • The factors of prognosis of malignant clear-cell neoplasms of the ovaries were revealed: the stage of the disease, the volume of surgery, the degree of tumor differentiation and the degree of cellular anaplasia. (inlibrary.uz)
  • Síndrome caracterizado por la triada de ÚLCERA PÉPTICA grava, hipersecreción de ÁCIDO GÁSTRICO y tumor secretor de GASTRINA, en el PÁNCREAS o en otros tejidos (GASTRINOMA). (bvsalud.org)
  • Viruses in Cancers of the Digestive System: Active Contributors or Idle Bystanders? (wikipedia.org)
  • Le Centre Fédéral d Expertise des Soins de Santé (KCE) et le Collège d Oncologie ont réalisé une mise à jour des recommandations de bonne pratique pour la prise en charge des cancers de l sophage et de l estomac, qui dataient de 2008. (docressources.info)
  • The mean age of the patients observed was 57.3 years (± 14.1), with a predominance of females and digestive system neoplasms as the main diagnosis. (rbfhss.org.br)
  • Despite the similarity of the clinical picture, diagnostic and therapeutic tactics, an extremely unfavorable prognosis for both forms of esophageal cancer, these malignant neoplasms have different risk factors, socio-geographic and ethnic characteristics, knowledge of which is necessary for the timely establishment of the diagnosis and preventive measures. (inlibrary.uz)
  • Neoplasms of the endocrine pancreas can be divided into functional and nonfunctional varieties. (medscape.com)
  • STELARA ® may decrease the activity of your immune system and increase your risk for certain types of cancer. (healthgrades.com)
  • It ranks second among the causes of digestive system cancer-related death [ 1 ]. (aging-us.com)
  • For the first time on a large clinical material, the results of the study of clinical and morphological features and prognostic factors of clear cell ovarian cancer and mixed malignant neoplasms of the ovaries with a mandatory clear cell component are presented. (inlibrary.uz)
  • Cancer of the digestive system is the most common cause of death among malignant neoplasms (Table 1). (inlibrary.uz)
  • According to the International Agency for Research on Cancer (IARC) for 2008, the incidence of cancer of the digestive system was 49.2 people per 100 thousand people per year, the mortality rate was 34.3 people per 100 thousand. (inlibrary.uz)
  • This graph shows the total number of publications written about "Sigmoid Neoplasms" by people in UAMS Profiles by year, and whether "Sigmoid Neoplasms" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Sigmoid Neoplasms" by people in Profiles over the past ten years. (uams.edu)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • There are many different and various pathologic classification for digestive system neoplasms. (wikipedia.org)
  • As in prior years, the majority (70.9%) of hospitalizations were associated with diagnoses in the categories of mental health disorders, pregnancy-related conditions, injury/poisoning, and digestive system disorders. (health.mil)
  • In 2020, 4 diagnostic categories accounted for 70.9% of all hospitalizations of active component members: mental health disorders (28.7%), pregnancy- and delivery-related conditions (25.1%), injury/poisoning (8.8%), and digestive system disorders (8.3%) (Table 1) . (health.mil)
  • In 2021, 4 diagnostic categories accounted for 71.2% of all hospitalizations of active component members: mental health disorders (31.3%), pregnancy- and delivery-related conditions (23.4%), injury/poisoning (8.7%), and digestive system disorders (7.8%) ( Table 1 ). (health.mil)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • Digestive System Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • Neoplasms that arise from endocrine tissue may also secrete hormones, resulting in excessive levels of these hormones in the body and potentially a wide variety of symptoms. (rarediseases.org)
  • Based on a comparative analysis of pure and mixed forms of clear cell neoplasms of the ovaries, their morphological signs and features of the clinical course of the disease were established. (inlibrary.uz)
  • This article provides a guide to the performance and interpretation of 68 Ga-DOTATATE PET/CT and describes its role in the diagnostic algorithm of neuroendocrine neoplasms and its overall utility in their management. (snmjournals.org)
  • Neuroendocrine neoplasms exhibit variable symptomatology, such as tumor mass effects or the biologic consequences of the bioactive amine secretion, frequently delaying diagnosis. (snmjournals.org)
  • Somatostatin receptor (SSR) imaging offers an opportunity to identify receptor-expressing neuroendocrine neoplasms (NENs) ( 2 , 3 ). (snmjournals.org)
  • The prognostic assessment of gastroenteropancreatic NENs has improved significantly since the introduction of the European Neuroendocrine Tumor Society and World Health Organization 2010 staging and grading systems. (snmjournals.org)
  • Reportability/Histology: Would a histology reading "Well-differentiated neuroendocrine neoplasm" of the appendix be reportable? (cancer.gov)
  • Well-differentiated neuroendocrine neoplasm" of the appendix is reportable. (cancer.gov)
  • WHO states on page 13 "The term 'neuroendocrine neoplasm' can be used synonymously with 'neuroendocrine tumor. (cancer.gov)
  • Neuroendocrine "tumor," or NET G1, is listed in the WHO classification as one of the malignant neoplasms of the appendix. (cancer.gov)
  • The WHO classification does not list well-differentiated neuroendocrine "neoplasm" of the appendix as a malignancy. (cancer.gov)
  • The clinical profiles, management, and prognostic factors of biliary mixed neuroendocrine nonneuroendocrine neoplasms: A systematic review of the literature. (nih.gov)
  • Neuroendocrine neoplasms of the appendix, colon and rectum. (nih.gov)
  • Molecular subtyping in pancreatic neuroendocrine neoplasms: New insights into clinical, pathological unmet needs and challenges. (nih.gov)
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
  • 21 per cent of deaths were caused by malignant neoplasms, 6.2 per cent - by external causes (in 2018, 55.4, 20.3, and 6.6 per cent respectively). (gov.lt)
  • Epidemiologic studies that estimated the effects of alcohol and tobacco consumption on the risk of cancers of the upper aero-digestive tract were identified from the MEDLINE database, 1966-2001. (cdc.gov)
  • 9. [Application of PET-CT in cancers of the digestive tract]. (nih.gov)
  • Rectal and Anorectal Narrowing (Strictures) The rectum is the final portion of the large intestine and marks the end of the digestive tract. (merckvetmanual.com)
  • A primary malignant neoplasm of epithelial liver cells. (wakehealth.edu)
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
  • A primary malignant neoplasm of the pancreatic islet cells. (icd10data.com)
  • Several other rare clinical syndromes have been proposed as possible functional endocrine syndromes associated with pancreatic neoplasms. (medscape.com)
  • At LA Integrative Gastroenterology & Nutrition , we treat a broad variety of conditions, ranging from traditional gastrointestinal disorders to ailments in other parts of the body that stem from the digestive system. (laintegrativegi.com)
  • Neoplasms of the endocrine pancreas can be divided into functional and nonfunctional varieties. (medscape.com)
  • A malignant endocrine neoplasm arising from islets of langerhans of the pancreas. (icd10data.com)
  • Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. (uams.edu)
  • This graph shows the total number of publications written about "Colorectal Neoplasms, Hereditary Nonpolyposis" by people in UAMS Profiles by year, and whether "Colorectal Neoplasms, Hereditary Nonpolyposis" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Colorectal Neoplasms, Hereditary Nonpolyposis" by people in Profiles over the past ten years. (uams.edu)
  • As in prior years, the majority (70.9%) of hospitalizations were associated with diagnoses in the categories of mental health disorders, pregnancy-related conditions, injury/poisoning, and digestive system disorders. (health.mil)
  • In 2020, 4 diagnostic categories accounted for 70.9% of all hospitalizations of active component members: mental health disorders (28.7%), pregnancy- and delivery-related conditions (25.1%), injury/poisoning (8.8%), and digestive system disorders (8.3%) (Table 1) . (health.mil)
  • The leading primary GI diagnoses were abdominal pain (4.7 million visits), nausea and vomiting (1.6 million visits), and functional disorders of the digestive system (0.7 million visits). (medscape.com)
  • Most pancreatic endocrine neoplasms discovered clinically are functional-that is, they secrete one or more hormonal products into the blood, which leads to a recognizable clinical syndrome. (medscape.com)
  • An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. (icd10data.com)
  • First-degree relatives of nonsmoking lung cancer cases were at 1.52-fold (95% CI, 1.02- 2.27) increased risk of cancer of the digestive system after adjustment for each relative's age, race, sex, and smoking status. (elsevierpure.com)
  • Appendix B, from the 1988 Vital Statistics of the United States mortality volume, provides a description of the mortality vital statistics system and cause of death coding. (cdc.gov)
  • 15. Clinical usefulness of 18-fluorodeoxyglucose positron emission tomography in the management of patients with nonpancreatic periampullary neoplasms. (nih.gov)
  • A subset of these patients have neoplasms that secrete pancreatic polypeptide (ie, PPomas). (medscape.com)