AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
DiastoleSystoleMyocardial ContractionVentricular Function, LeftEchocardiography, DopplerHeart VentriclesBlood Flow VelocityMitral ValveEchocardiographyVentricular FunctionDogsHeartCoronary CirculationModels, CardiovascularCardiac VolumeEchocardiography, Doppler, ColorEchocardiography, Doppler, PulsedHeart AuscultationStroke VolumeHemodynamicsVentricular Dysfunction, LeftCardiac-Gated Imaging TechniquesVentricular PressureBlood PressurePhonocardiographyKinetocardiographyTorsion, MechanicalElasticityPericardiumHeart SeptumVentricular Function, RightHeart RateAtrial Function, LeftMyocardiumEndocardiumFetal HeartHeart SoundsAtrial FunctionMitral Valve InsufficiencyMyocardial BridgingAortic Valve InsufficiencyElectrocardiographyHeart DiseasesMagnetic Resonance Imaging, CineCoronary VesselsHeart AtriaCardiomyopathy, RestrictivePulsatile FlowHypertrophy, Left VentricularTime FactorsAngiocardiographyDuctus ArteriosusMitral Valve StenosisCardiac CatheterizationAtrial Function, RightAortic ValvePapillary MusclesSarcomeresCardiac Pacing, ArtificialCardiomyopathy, DilatedEchocardiography, Three-DimensionalPulmonary ValveVentricular Dysfunction, RightComplianceConnectinHeart FailurePericarditis, ConstrictiveReference ValuesCineangiographyCardiac OutputVascular ResistanceRegional Blood FlowReproducibility of ResultsPressureSheepTricuspid ValveStress, MechanicalPulmonary Wedge PressureEchocardiography, TransesophagealElasticity Imaging TechniquesMyocytes, CardiacAortaCardiomyopathy, HypertrophicTricuspid Valve InsufficiencyImage Interpretation, Computer-AssistedPulseMyxomaUltrasonography, PrenatalTetralogy of FallotMotionObserver VariationImage Processing, Computer-AssistedPulmonary CirculationCardiomyopathiesPerfusionBiomechanical PhenomenaCardiomegalyHeart Valve ProsthesisBlood VolumeArteries
Diastole
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Systole
Period of contraction of the HEART, especially of the HEART VENTRICLES.
Myocardial Contraction
Contractile activity of the MYOCARDIUM.
Ventricular Function, Left
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Echocardiography, Doppler
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Heart Ventricles
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Blood Flow Velocity
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Mitral Valve
The valve between the left atrium and left ventricle of the heart.
Echocardiography
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Ventricular Function
The hemodynamic and electrophysiological action of the HEART VENTRICLES.
Dogs
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Heart
The hollow, muscular organ that maintains the circulation of the blood.
Coronary Circulation
The circulation of blood through the CORONARY VESSELS of the HEART.
Models, Cardiovascular
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
Cardiac Volume
The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.
Echocardiography, Doppler, Color
Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.
Echocardiography, Doppler, Pulsed
Echocardiography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.
Heart Auscultation
Act of listening for sounds within the heart.
Stroke Volume
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Hemodynamics
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Cardiac-Gated Imaging Techniques
Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.
Ventricular Pressure
The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.
Blood Pressure
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Phonocardiography
Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.
Kinetocardiography
The graphic recording of chest wall movement due to cardiac impulses.
Torsion, Mechanical
A twisting deformation of a solid body about an axis. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Elasticity
Resistance and recovery from distortion of shape.
Pericardium
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Heart Septum
This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.
Ventricular Function, Right
The hemodynamic and electrophysiological action of the right HEART VENTRICLE.
Heart Rate
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
Atrial Function, Left
The hemodynamic and electrophysiological action of the LEFT ATRIUM.
Myocardium
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Endocardium
The innermost layer of the heart, comprised of endothelial cells.
Fetal Heart
The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.
Heart Sounds
The sounds heard over the cardiac region produced by the functioning of the heart. There are four distinct sounds: the first occurs at the beginning of SYSTOLE and is heard as a "lubb" sound; the second is produced by the closing of the AORTIC VALVE and PULMONARY VALVE and is heard as a "dupp" sound; the third is produced by vibrations of the ventricular walls when suddenly distended by the rush of blood from the HEART ATRIA; and the fourth is produced by atrial contraction and ventricular filling.
Atrial Function
The hemodynamic and electrophysiological action of the HEART ATRIA.
Mitral Valve Insufficiency
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Myocardial Bridging
A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.
Aortic Valve Insufficiency
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities.
Magnetic Resonance Imaging, Cine
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
Coronary Vessels
The veins and arteries of the HEART.
Heart Atria
The chambers of the heart, to which the BLOOD returns from the circulation.
Cardiomyopathy, Restrictive
A form of CARDIAC MUSCLE disease in which the ventricular walls are excessively rigid, impeding ventricular filling. It is marked by reduced diastolic volume of either or both ventricles but normal or nearly normal systolic function. It may be idiopathic or associated with other diseases (ENDOMYOCARDIAL FIBROSIS or AMYLOIDOSIS) causing interstitial fibrosis.
Pulsatile Flow
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
Hypertrophy, Left Ventricular
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
Angiocardiography
Radiography of the heart and great vessels after injection of a contrast medium.
Ductus Arteriosus
A fetal blood vessel connecting the pulmonary artery with the descending aorta.
Mitral Valve Stenosis
Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.
Cardiac Catheterization
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Atrial Function, Right
The hemodynamic and electrophysiological action of the RIGHT ATRIUM.
Aortic Valve
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
Papillary Muscles
Conical muscular projections from the walls of the cardiac ventricles, attached to the cusps of the atrioventricular valves by the chordae tendineae.
Sarcomeres
The repeating contractile units of the MYOFIBRIL, delimited by Z bands along its length.
Cardiac Pacing, Artificial
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Cardiomyopathy, Dilated
A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
Echocardiography, Three-Dimensional
Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)
Pulmonary Valve
A valve situated at the entrance to the pulmonary trunk from the right ventricle.
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Compliance
Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
Connectin
A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line.
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Pericarditis, Constrictive
Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
Reference Values
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Cineangiography
Motion pictures of the passage of contrast medium through blood vessels.
Cardiac Output
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Vascular Resistance
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Regional Blood Flow
The flow of BLOOD through or around an organ or region of the body.
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Pressure
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Sheep
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Tricuspid Valve
The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.
Stress, Mechanical
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
Pulmonary Wedge Pressure
The blood pressure as recorded after wedging a CATHETER in a small PULMONARY ARTERY; believed to reflect the PRESSURE in the pulmonary CAPILLARIES.
Echocardiography, Transesophageal
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
Elasticity Imaging Techniques
Non-invasive imaging methods based on the mechanical response of an object to a vibrational or impulsive force. It is used for determining the viscoelastic properties of tissue, and thereby differentiating soft from hard inclusions in tissue such as microcalcifications, and some cancer lesions. Most techniques use ultrasound to create the images - eliciting the response with an ultrasonic radiation force and/or recording displacements of the tissue by Doppler ultrasonography.
Myocytes, Cardiac
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
Aorta
The main trunk of the systemic arteries.
Cardiomyopathy, Hypertrophic
A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
Tricuspid Valve Insufficiency
Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.
Image Interpretation, Computer-Assisted
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
Pulse
The rhythmical expansion and contraction of an ARTERY produced by waves of pressure caused by the ejection of BLOOD from the left ventricle of the HEART as it contracts.
Myxoma
A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)
Ultrasonography, Prenatal
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
Tetralogy of Fallot
A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.
Motion
Physical motion, i.e., a change in position of a body or subject as a result of an external force. It is distinguished from MOVEMENT, a process resulting from biological activity.
Observer Variation
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Image Processing, Computer-Assisted
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Pulmonary Circulation
The circulation of the BLOOD through the LUNGS.
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
Perfusion
Treatment process involving the injection of fluid into an organ or tissue.
Biomechanical Phenomena
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Cardiomegaly
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Heart Valve Prosthesis
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
Blood Volume
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
Arteries
The vessels carrying blood away from the heart.
Sarcoplasmic Reticulum
A network of tubules and sacs in the cytoplasm of SKELETAL MUSCLE FIBERS that assist with muscle contraction and relaxation by releasing and storing calcium ions.
Dilatation, Pathologic
The condition of an anatomical structure's being dilated beyond normal dimensions.
Laser-Doppler Flowmetry
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
Magnetic Resonance Imaging
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Prospective Studies
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Action Potentials
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
Pulmonary Artery
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Hyperemia
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Coronary Angiography
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Heart Neoplasms
Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
Coronary Stenosis
Narrowing or constriction of a coronary artery.
Ultrasonography, Doppler
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Ventricular Remodeling
The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.
Heart Conduction System
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
Ryanodine Receptor Calcium Release Channel
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Arrhythmias, Cardiac
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Dobutamine
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Gestational Age
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
Heart-Assist Devices
Small pumps, often implantable, designed for temporarily assisting the heart, usually the LEFT VENTRICLE, to pump blood. They consist of a pumping chamber and a power source, which may be partially or totally external to the body and activated by electromagnetic motors.
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Rabbits
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Linear Models
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.

Ambulatory blood pressure monitoring and progression in patients with IgA nephropathy. (1/2997)

BACKGROUND: Hypertension is a recognized marker of poor prognosis in IgA nephropathy. METHODS: The present study investigated the prevalence of white-coat hypertension, the diurnal rhythm of blood pressure (BP), the effectiveness of antihypertensive drug therapy, and the effect of the above on the progression of the kidney disease in IgA nephropathy. One hundred twenty-six IgA nephropathy patients were selected consecutively for 24-h ambulatory blood pressure monitoring (ABPM). Fifty-five patients were normotensive and 71 were treated hypertensives. Their antihypertensive drugs were angiotensin-converting enzyme inhibitors (ACEI) alone or in combination with calcium-channel blockers (CCB). RESULTS: The mean night-time BP of normotensives (108+/-9/67+/-6 mmHg) was significantly lower than their day-time BP (125+/-8/82+/-7 mmHg, P<0.05). There was no significant difference between the mean day-time and night-time BP in hypertensive patients (125+/-9/82+/-7 mmHg vs 128+/-10/85+/-9 mmHg). The circadian variation of BP was preserved ('dippers') in 82% of the normotensive and 7% of the hypertensive patients (P<0.001). There were 10 'white-coat hypertensives' among the patients classified as normotensives with ABPM (mean office blood pressure 149+/-7/96+/-8 mmHg, 24-h blood pressure 127+/-6/83+/-5 mmHg, P<0.05) and 14 among treated hypertensives (mean office BP 152+/-8/98+/-6 mmHg, 24-h BP 130+/-4/85+/-8 mmHg, P<0.05). There was no difference in mean day-time BP among normotensive and treated hypertensive patients (125+/-8/81+/-5 mmHg vs 128+/-10/85+/-9 mmHg). Hypertensives had significantly higher night-time BP (125+/-9/85+/-9 mmHg) than normotensives (108+/-9/67+/-6 mmHg, P<0.001). There was no difference in serum creatinine levels among the different groups at the time of the ABPM. However, thirty-six+/-4.1 months after the ABPM, hypertensive patients (n=52) had higher serum creatinine levels (124+/-32 micromol/l) than at the time of the ABPM (101+/-28 micromol/l). The serum creatinine of normotensive patients (n=43) did not change during the follow-up period. 'Non-dipper' normotensives (n=10) had significantly higher serum creatinine levels at the end of the follow-up period than at its beginning (106+/-17 micromol/l vs 89+/-18 micromol/l, P<0.05). There was no increase in serum creatinine of 'dipper' normotensives. The mean serum creatinine of 'white-coat hypertensives' was significantly higher at the end of the study period than at its beginning. CONCLUSIONS: There is no diurnal blood pressure variation in most of the hypertensive IgA nephropathy patients. ACEI and CCB treatment have better effect on day-time than night-time hypertension. The lack of the circadian rhythm and 'white-coat hypertension' seems to accelerate the progression of IgA nephropathy.  (+info)

Restriction of placental and fetal growth in sheep alters fetal blood pressure responses to angiotensin II and captopril. (2/2997)

1. We have measured arterial blood pressure between 115 and 145 days gestation in normally grown fetal sheep (control group; n = 16) and in fetal sheep in which growth was restricted by experimental restriction of placental growth and development (PR group; n = 13). There was no significant difference in the mean gestational arterial blood pressure between the PR (42.7 +/- 2.6 mmHg) and control groups (37.7 +/- 2.3 mmHg). Mean arterial blood pressure and arterial PO2 were significantly correlated in control animals (r = 0.53, P < 0.05, n = 16), but not in the PR group. 2. There were no changes in mean arterial blood pressure in either the PR or control groups in response to captopril (7.5 microg captopril min-1; PR group n = 7, control group n = 6) between 115 and 125 days gestation. After 135 days gestation, there was a significant decrease (P < 0.05) in the fetal arterial blood pressure in the PR group but not in the control group during the captopril infusion (15 microg captopril min-1; PR group n = 7, control group n = 6). 3. There was a significant effect (F = 14.75; P < 0.001) of increasing doses of angiotensin II on fetal diastolic blood pressure in the PR and control groups. The effects of angiotensin II were different (F = 8.67; P < 0.05) in the PR and control groups at both gestational age ranges. 4. These data indicate that arterial blood pressure may be maintained by different mechanisms in growth restricted fetuses and normally grown counterparts and suggests a role for the fetal renin-angiotensin system in the maintenance of blood pressure in growth restricted fetuses.  (+info)

Contribution of L-type Ca2+ current to electrical activity in sinoatrial nodal myocytes of rabbits. (3/2997)

The role of L-type calcium current (ICa,L) in impulse generation was studied in single sinoatrial nodal myocytes of the rabbit, with the use of the amphotericin-perforated patch-clamp technique. Nifedipine, at a concentration of 5 microM, was used to block ICa,L. At this concentration, nifedipine selectively blocked ICa,L for 81% without affecting the T-type calcium current (ICa,T), the fast sodium current, the delayed rectifier current (IK), and the hyperpolarization-activated inward current. Furthermore, we did not observe the sustained inward current. The selective action of nifedipine on ICa,L enabled us to determine the activation threshold of ICa,L, which was around -60 mV. As nifedipine (5 microM) abolished spontaneous activity, we used a combined voltage- and current-clamp protocol to study the effects of ICa,L blockade on repolarization and diastolic depolarization. This protocol mimics the action potential such that the repolarization and subsequent diastolic depolarization are studied in current-clamp conditions. Nifedipine significantly decreased action potential duration at 50% repolarization and reduced diastolic depolarization rate over the entire diastole. Evidence was found that recovery from inactivation of ICa,L occurs during repolarization, which makes ICa,L available already early in diastole. We conclude that ICa,L contributes significantly to the net inward current during diastole and can modulate the entire diastolic depolarization.  (+info)

Changes in porcine transmitral flow velocity pattern and its diastolic determinants during partial coronary occlusion. (4/2997)

OBJECTIVES: To define the mechanical determinants of transmitral flow and the effect of heart rate during regional ischemia. BACKGROUND: Myocardial ischemia changes the transmitral flow velocity pattern due to disease-induced changes in the heart's diastolic properties. METHODS: Regional ischemia was produced in 12 pigs by partially occluding the left anterior descending coronary artery until segment-length shortening in the ischemic region fell by 20%. Transmitral flow velocity patterns and their determinants were measured under two conditions, baseline and ischemia, at two heart rates, 70 and 90 beats/min. RESULTS: Regional ischemia had a significant effect on two determinants of filling: relaxation, which was slower, and chamber stiffness, which increased. These changes were associated with reduced contractility and increased myocardial stiffness, resulting in an early transmitral flow pattern that was flatter and narrower, but no change in the late flow pattern. Moderate increases in heart rate accelerated relaxation and decreased atrioventricular pressure gradient but had no effect on contractility or myocardial or chamber stiffness, resulting in an early transmitral flow pattern that was flatter and narrower and an increased late flow velocity. CONCLUSIONS: This model of regional ischemia leads to a flatter and narrower early transmitral flow velocity pattern and no change in late flow due to a combination of slowed left ventricular relaxation and increased chamber stiffness. Reflex increases in heart rate that accompany ischemia tend to mask this effect.  (+info)

Decreased left ventricular filling pressure 8 months after corrective surgery in a 55-year-old man with tetralogy of Fallot: adaptation for increased preload. (5/2997)

A 55-year-old man with tetralogy of Fallot underwent corrective surgery. Left ventricular filling pressure increased markedly with increased left ventricular volume one month after surgery, then decreased over the next 7 months, presumably due to increased left ventricular compliance.  (+info)

Cell death in acromegalic cardiomyopathy. (6/2997)

BACKGROUND: Prolonged untreated acromegaly leads to a nonspecific myopathy characterized by ventricular dysfunction and failure. However, the mechanisms responsible for the alterations of cardiac pump function remain to be defined. Because cell death is implicated in most cardiac disease processes, the possibility has been raised that myocyte apoptosis may occur in the acromegalic heart, contributing to the deterioration of ventricular hemodynamics. METHODS AND RESULTS: Ten acromegalic patients with diastolic dysfunction and 4 also with systolic dysfunction were subjected to electrocardiography, Holter monitoring, 2-dimensional echocardiography, cardiac catheterization, and biventricular and coronary angiography before surgical removal of a growth hormone-secreting pituitary adenoma. Endomyocardial biopsies were obtained and analyzed quantitatively in terms of tissue scarring and myocyte and nonmyocyte apoptosis. Myocardial samples from papillary muscles of patients who underwent valve replacement for mitral stenosis were used for comparison. The presence of apoptosis in myocytes and interstitial cells was determined by confocal microscopy with the use of 2 histochemical methods, consisting of terminal deoxynucleotidyl transferase (TdT) assay and Taq probe in situ ligation. Acromegaly was characterized by a 495-fold and 305-fold increase in apoptosis of myocytes and nonmyocytes, respectively. The magnitude of myocyte apoptosis correlated with the extent of impairment in ejection fraction and the duration of the disease. A similar correlation was found with the magnitude of collagen accumulation, indicative of previous myocyte necrosis. Myocyte death was independent from the hormonal levels of growth hormone and insulin-like growth factor-1. Apoptosis of interstitial cells did not correlate with ejection fraction. CONCLUSIONS: Myocyte cell death, apoptotic and necrotic in nature, may be critical for the development of ventricular dysfunction and its progression to cardiac failure with acromegaly.  (+info)

Hypertension treatment and the prevention of coronary heart disease in the elderly. (7/2997)

Both isolated systolic hypertension (>140 mm Hg/<90 mm Hg) and systolic/diastolic hypertension (>140 mm Hg/>90 mm Hg) are major risk factors for cardiovascular disease in the elderly. Specific antihypertensive drug therapy is available if lifestyle interventions fail to reduce blood pressure to a normal level. Diuretics and beta blockers both reduce the occurrence of adverse events related to cerebrovascular disease; however, diuretics are more effective in reducing events related to coronary heart disease. Treated patients are less likely to develop severe hypertension or congestive heart failure. In most instances, low-dose diuretic therapy should be used as initial antihypertensive therapy in the elderly. A long-acting dihydropyridine calcium channel blocker may be used as alternative therapy in elderly patients with isolated systolic hypertension. Trials are being conducted to evaluate the long-term effects of angiotensin converting enzyme inhibitors and angiotensin-II receptor blockers in elderly patients with uncomplicated hypertension.  (+info)

Early detection of anthracycline induced cardiotoxicity in asymptomatic patients with normal left ventricular systolic function: autonomic versus echocardiographic variables. (8/2997)

OBJECTIVE: To investigate left ventricular dysfunction in patients who had been treated with anthracycline based chemotherapy. METHODS: Autonomic function was compared with left ventricular diastolic function in 20 asymptomatic women with normal systolic function (left ventricular ejection fraction (LVEF) > 0.50) treated for breast cancer with high dose anthracycline based chemotherapy, and 20 age matched healthy controls. Left ventricular diastolic function was assessed echocardiographically by measuring the early peak flow velocity to atrial peak flow velocity ratio, isovolumic relaxation time, and deceleration time. Heart rate variability analysis was assessed for time domain and frequency domain parameters. RESULTS: The mean (SD) age of the patients was 45 (7) years and the mean LVEF was 0.59 (0.06). The time interval after the end of chemotherapy was 29 (27) months. One or more diastolic variables were abnormal in 50% of the patients. Heart rate variability was abnormal in 85% of patients. Mean values of both time domain and frequency domain parameters were decreased (p < 0.05), in particular the parasympathetic indices. CONCLUSIONS: Autonomic impairment occurs in a large proportion of asymptomatic patients with normal systolic left ventricular function after high dose anthracycline based chemotherapy. In particular, heart rate variability analysis may be a sensitive tool to identify the first signs of cardiotoxicity in these patients.  (+info)

Change in left ventricular diastolic filling patterns in patients with supraventricular tachycardia treated by radiofrequency...
TY - JOUR. T1 - Change in left ventricular diastolic filling patterns in patients with supraventricular tachycardia treated by radiofrequency ablation. T2 - A Doppler echocardiographic study. AU - Shyu, K. G.. AU - Lin, J. L.. AU - Chen, J. J.. AU - Ko, Y. L.. AU - Hwang, J. J.. AU - Tseng, Y. Z.. AU - Lien, W. P.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 1994/1/1. Y1 - 1994/1/1. N2 - To evaluate changes in left ventricular diastolic filling patterns resulting from radiofrequency ablation for supraventricular tachycardia (SVT), 44 patients with SVT undergoing radiofrequency ablation (study group), and 16 patients with SVT undergoing electrophysiologic study without ablation (control group) were studied by pulsed Doppler echocardiography. Peak early diastolic filling velocity (E), peak atrial filling velocity (A), and an E/A ratio were obtained from the transmitral flow velocity pattern before and 24-48 h after ablation or electrophysiologic study. In the study ...
https://tmu.pure.elsevier.com/en/publications/change-in-left-ventricular-diastolic-filling-patterns-in-patients
Relation Between Left Ventricular Diastolic Pressure and Myocardial Segment Length and Observations on the Contribution of...Relation Between Left Ventricular Diastolic Pressure and Myocardial Segment Length and Observations on the Contribution of...
A method is described for the continuous recording of changes in the length of a segment of left ventricular myocardium, and its advantages and limitations are discussed. The curve depicting the relation between ventricular diastolic pressure and simultaneous changes in the length of a myocardial segment is presented. For a given increment in pressure, the myocardial segment length increases more at low ventricular diastolic pressure than at high pressure. Atrial systole causes a substantial increase in myocardial segment length when the ventricle is on the sensitive part of its pressure-length curve.. ...
http://circres.ahajournals.org/content/8/5/1092
A new approach for evaluation of left ventricular diastolic function: Spatial and temporal analysis of left ventricular filling...
TY - JOUR. T1 - A new approach for evaluation of left ventricular diastolic function. T2 - Spatial and temporal analysis of left ventricular filling flow propagation by color M-mode Doppler echocardiography. AU - Takatsuji, Hiroya. AU - Mikami, Taisei. AU - Urasawa, Kazushi. AU - Teranishi, Jun Ichi. AU - Onozuka, Hisao. AU - Takagi, Chika. AU - Makita, Yasuhiro. AU - Matsuo, Hisashi. AU - Kusuoka, Hideo. AU - Kitabatake, Akira. PY - 1996/2. Y1 - 1996/2. N2 - Objectives. To evaluate left ventricular diastolic function and differentiate the pseudonormalized transmitral flow pattern from the normal pattern, the propagation of left ventricular early filling flow was assessed quantitatively using color M-mode Doppler echocardiography. Background. Because the propagation of left ventricular early filling flow is disturbed in the left ventricle with impaired relaxation, quantification of such alterations should provide useful indexes for the evaluation of left ventricular diastolic function Methods. ...
https://jhu.pure.elsevier.com/en/publications/a-new-approach-for-evaluation-of-left-ventricular-diastolic-funct-4
Potassium depletion exacerbates essential hypertension. Contribution of external forces to left ventricular diastolic pressure:...Potassium depletion exacerbates essential hypertension. Contribution of external forces to left ventricular diastolic pressure:...
Potassium depletion exacerbates essential hypertension. Contribution of external forces to left ventricular diastolic pressure: implications for the clinical use of the Starling law
http://www.readabstracts.com/Health/Potassium-depletion-exacerbates-essential-hypertension-Contribution-of-external-forces-to-left-ventr.html
Left Ventricular End-Diastolic Pressure-Volume Relationship in Se...: Ingenta ConnectLeft Ventricular End-Diastolic Pressure-Volume Relationship in Se...: Ingenta Connect
To estimate changes in compliance, we evaluated the effects of sepsis on the end-diastolic pressure-volume relationship (EDPVR) in the left ventricle of rats that had undergone an open thorax procedure. Sepsis was induced in male Wistar Hannover rats (n = 7; 240 to 270 g) by intraperitoneal administration of a slurry of cecal contents; control rats (n = 7) were given 5% dextrose only. On the third day after induction of sepsis, left ventricular (LV) pressure and LV dimensions were recorded simultaneously in animals of both groups. Using a micromanometer and ultrasonic crystals, measurements were obtained at baseline and during the increase of afterload. Blood samples were taken for determination of complete blood count, white blood cell differential count, and lactate concentration, and for bacteriologic examination. Septic rats lost weight, and developed changes in body temperature, ascites, and abscesses in the abdominal and thoracic cavities, gram-negative bacteremia, and increase in heart ...
http://www.ingentaconnect.com/content/aalas/cm/2003/00000053/00000005/art00005
The natural history of isolated left ventricular diastolic dysfunction<...
TY - JOUR. T1 - The natural history of isolated left ventricular diastolic dysfunction. AU - Brogan, Walter C.. AU - Hillis, L. David. AU - Flores, Eduardo D.. AU - Lange, Richard A.. PY - 1992. Y1 - 1992. N2 - study objective: To assess the natural history of isolated left ventricular diastolic dysfunction. materials and methods: Follow-up (average duration, 68 months) was obtained in 51 patients with isolated left ventricular diastolic dysfunction at cardiac catheterization, characterized by (1) an elevated left ventricular end-diastolic pressure; (2) normal left ventricular end-diastolic and end-systolic volumes; (3) normal left ventricular ejection fraction; (4) no coronary artery disease; and (5) no valvular disease. results: During follow-up, seven patients died, but only one died of cardiac causes. Of the 44 living subjects, 20 (45%) noted new-onset symptoms of congestive heart failure, with 11 (25%) of these requiring hospitalization, and 12 (27%) required hospitalization for recurrent ...
https://jhu.pure.elsevier.com/en/publications/the-natural-history-of-isolated-left-ventricular-diastolic-dysfun-5
Peak negative myocardial velocity gradient in early diastole as a noninvasive indicator of left ventricular diastolic function ...Peak negative myocardial velocity gradient in early diastole as a noninvasive indicator of left ventricular diastolic function ...
In this study we sought to assess the clinical significance of peak negative MVG derived from TDI as a noninvasive indicator of LV diastolic function. By comparing peak negative MVG among patients with or without impairment of systolic and diastolic performance, we have demonstrated that peak negative MVG reflected diastolic abnormalities in these patients. We have also found that peak negative MVG was relatively independent of preload alterations because peak negative MVG was unaltered, while the transmitral flow velocity indices were significantly altered, by passive leg lifting maneuver. Finally, we have found that peak negative MVG showed an improvement by volume-reducing therapy in contrast to the transmitral flow velocity indices, which apparently worsened toward an abnormal relaxation pattern. Thus, peak negative MVG may be a noninvasive indicator of LV diastolic function that is relatively independent of preload alterations, and thereby could be used for the follow-up of patients with ...
http://www.onlinejacc.org/content/32/5/1418
Effect of changes in ventricular relaxation on early diastolic coronary blood flow in canine hearts. | Circulation ResearchEffect of changes in ventricular relaxation on early diastolic coronary blood flow in canine hearts. | Circulation Research
Since the gradient between aortic pressure and left ventricular diastolic pressure is a major determinant of coronary blood flow, a change in left ventricular relaxation by its effect on early diastole could diminish early diastolic coronary flow. Two interventions that resulted in impaired left ventricular relaxation, hypothermia, and reperfusion following a left anterior descending coronary artery occlusion were studied to evaluate whether there were associated changes in coronary blood flow. With both interventions, there was a significant prolongation of left ventricular relaxation (p less than 0.01) accompanied by a significant decrease in early diastolic coronary blood flow (p less than 0.01). Verapamil did not have a significant effect on these hemodynamic changes during hypothermia. However, verapamil significantly blunted the effects of reperfusion following ischemia on ventricular relaxation (p less than 0.002) and early diastolic coronary blood flow (p less than 0.01). Thus, impaired ...
http://circres.ahajournals.org/content/61/5/747
Clinical Utility of Single-Beat E/e′ Obtained by Simultaneous Recording of Flow and Tissue Doppler Velocities in Atrial...Clinical Utility of Single-Beat E/e′ Obtained by Simultaneous Recording of Flow and Tissue Doppler Velocities in Atrial...
Atrial fibrillation (AF) is the most frequent form of arrhythmia, and the number of patients with AF has increased with the rapid aging of society (1). AF is an important risk factor for heart failure (2), wherein left ventricular (LV) diastolic function is more closely related to the symptoms, exercise tolerance, and prognosis of patients compared with systolic function (3,4). In the clinical setting, LV diastolic function is mainly evaluated by the transmitral flow velocity pattern using Doppler echocardiography. Evaluation of LV diastolic function is also needed in patients with AF which is extremely challenging because of the lack of atrial systolic transmitral flow wave and the irregularity of Doppler parameters caused by irregular R-R intervals (5-7).. As an alternative method for evaluating LV diastolic function, mitral annular velocity waveforms, which can be recorded using tissue Doppler echocardiography, have been used. The ratio of early diastolic transmitral flow velocity (E) to ...
http://imaging.onlinejacc.org/content/2/10/1147
Usefulness of tissue doppler and color M-mode indexes of left ventricular diastolic function in predicting outcomes in systolic...
TY - JOUR. T1 - Usefulness of tissue doppler and color M-mode indexes of left ventricular diastolic function in predicting outcomes in systolic left ventricular heart failure (from the ADEPT Study). AU - Troughton, Richard W.. AU - Prior, David L.. AU - Frampton, Christopher M.. AU - Nash, Patrick J.. AU - Pereira, Jeremy J.. AU - Martin, Maureen. AU - Fogarty, Annette. AU - Morehead, Annitta J.. AU - Starling, Randall C.. AU - Young, James B.. AU - Thomas, James D.. AU - Lauer, Michael S.. AU - Klein, Allan L.. PY - 2005/7/15. Y1 - 2005/7/15. N2 - The prognostic values of tissue Doppler imaging and color M-mode diastolic indexes were studied in 225 patients who had symptomatic systolic heart failure in the ADEPT study. The primary end point of death, transplantation, or hospitalization due to heart failure occurred in 65 patients and was independently predicted by shorter deceleration time, lower ratio of pulmonary vein systolic to diastolic velocity, and increasing levels of the ratios of ...
https://www.scholars.northwestern.edu/en/publications/usefulness-of-tissue-doppler-and-color-m-mode-indexes-of-left-ven
DIAFAX I+II-Effects of Inhalative Anesthetics on Left Ventricular Diastolic Function - Full Text View - ClinicalTrials.govDIAFAX I+II-Effects of Inhalative Anesthetics on Left Ventricular Diastolic Function - Full Text View - ClinicalTrials.gov
Anaesthetics may impair the diastolic function of the heart, but the importance of this finding for patients has not been sufficiently examined. Specially the effects on diastolic function in patients with diastolic dysfunction has to be determined. The aim of this study is to examine the effect of isoflurane (only part I), sevoflurane and desflurane (part I+II) on the diastolic left ventricular function by doppler echocardiography ...
https://clinicaltrials.gov/ct2/show/NCT00244517
Assessment of left ventricular diastolic functionAssessment of left ventricular diastolic function
In a number of patients with EF 60% or more, signs of heart failure are clinically detected. As a rule, such a condition is caused by LV diastolic dysfunction (impaired relaxation processes due to ischemia, cardiosclerosis, hypertrophy of the walls, pericardial effusion, etc.). According to a number of researchers, patients with signs of heart failure caused only by diastolic dysfunction constitute 15-25% of all patients with HF.. Diastolic dysfunction of the LV is estimated according to the results of a study of transmitral diastolic blood flow in a pulsed mode. Determine: 1. the maximum speed of the early peak of the diastolic filling M1, 2. the maximum speed in the atrial systole M2, 3. the integral of speed (area under the curve) of the early diastolic filling (VTI E), 4. the integral of the speed of atrial systole (VTI A), 5 LV isovolumetric relaxation time (IVRT), 6. time to slow the early diastolic filling (DT).. In the early stages of LV diastolic dysfunction with a slight increase in ...
https://your-cholesterol-faq.com/blog/assessment-of-left-ventricular-diastolic-function/
Left Ventricular Diastolic Dysfunction in Peritoneal Dialysis<...
TY - JOUR. T1 - Left Ventricular Diastolic Dysfunction in Peritoneal Dialysis. AU - Wu, Cho Kai. AU - Lee, Jen Kuang. AU - Wu, Yi Fan. AU - Tsai, Chia Ti. AU - Chiang, Fu Tien. AU - Hwang, Juey Jen. AU - Lin, Jiunn Lee. AU - Hung, Kuan Yu. AU - Huang, Jenq Wen. AU - Lin, Jou Wei. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Left ventricular diastolic dysfunction (LVDD) is common among patients undergoing peritoneal dialysis (PD). We examined the relationship between LVDD, major adverse cardiovascular events (MACE), and mortality in PD patients. A total of 149 patients undergoing PD with preserved left ventricular systolic function were included and followed for 3.5 years. LVDD was diagnosed (according to the European Society of Cardiology guidelines) by conventional and tissue Doppler echocardiography. Serum high-sensitivity C-reactive protein (hsCRP) was measured. The location and volume of adipose tissue were assessed by computed tomography (CT) at the level of the fourth lumbar vertebra. Subjects with ...
https://tmu.pure.elsevier.com/en/publications/left-ventricular-diastolic-dysfunction-in-peritoneal-dialysis
Relationship of diastolic intraventricular pressure gradients and aerobic capacity in patients with diastolic heart failure |...Relationship of diastolic intraventricular pressure gradients and aerobic capacity in patients with diastolic heart failure |...
Our study demonstrated an increase in LV relaxation during diastole (inferred from the absolute increase in IVPG) with exercise in both normal subjects and in patients with heart failure. However, this mechanism was significantly impaired in the heart failure group compared with normal subjects. We provided evidence for a strong relationship between the ability to augment the diastolic LV relaxation (represented by the delta IVPG) with exercise and the V̇o2 max. Our study also demonstrated that in patients with heart failure, the decreased ability to augment the diastolic relaxation is responsible for the inability to accommodate the increase in estimated preload during exercise, resulting in higher filling pressures.. Regional diastolic pressure differences have been identified in the left ventricle only recently and their importance in determining diastolic function now becomes evident. Ling and colleagues (25) described the suction effect that develops secondary to a pressure drop between ...
http://ajpheart.physiology.org/content/289/5/H2081?ijkey=1e549d459f173eef8fae62e529a14cfc5f8fe578&keytype2=tf_ipsecsha
eCite - Reliability of updated left ventricular diastolic function recommendations in predicting elevated left ventricular...eCite - Reliability of updated left ventricular diastolic function recommendations in predicting elevated left ventricular...
Reliability of updated left ventricular diastolic function recommendations in predicting elevated left ventricular filling pressure and prognosis
http://ecite.utas.edu.au/116525
Vasodilator Drugs: Acute Vasodilator Intervention - Nitroglycerin - Infectious Disease AdvisorVasodilator Drugs: Acute Vasodilator Intervention - Nitroglycerin - Infectious Disease Advisor
Nitroglycerin acts through the NO receptor to activate guanylyl cyclase to increase cGMP and perhaps through other yet undefined mechanisms.. IV nitroglycerin reduces left ventricular diastolic pressure, pulmonary capillary wedge pressure, right ventricular diastolic pressure and right atrial pressure. With continued advancement of dose, there is also a fall in systemic and pulmonary vascular resistance, with a consequent modest rise in cardiac output. Some of the improved hemodynamics is also related to a decrease in mitral regurgitation. Again, the hemodynamic effects are less dramatic than those noted for nitroprusside.. The hemodynamic responses to nitroglycerin tend to gradually decrease with time. Starting as early as 12 to 24 hours into the infusion, the central hemodynamic effects tend to gradually return toward baseline; increasing the dose (infusion rate) may be effective in reversing this trend, but not uniformly so.. This waning of the response has not been fully elucidated, but ...
https://www.infectiousdiseaseadvisor.com/home/decision-support-in-medicine/cardiology/vasodilator-drugs-acute-vasodilator-intervention-nitroglycerin/
Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults: The Atherosclerosis Risk in Communities Study |...Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults: The Atherosclerosis Risk in Communities Study |...
Background-While age-associated changes in LV diastolic function are well-recognized, limited data exist characterizing measures of diastolic function in older adults, including both reference ranges reflecting the older adult population and prognostically relevant values for incident HF, as well as their associations with circulating biomarkers of heart failure (HF) risk.. Methods-Among 5,801 elderly participants in the Atherosclerosis Risk in Communities (ARIC) study (age range 67-90, mean age 76 ± 5, 42% male, 21% black), we determined the continuous association of diastolic measures (TDI e, E/e, and left atrial size) with concomitant NT-proBNP and subsequent HF hospitalization or death. We also determined sex-specific 10th and 90th percentile limits for these measures using quantile regression in 401 participants free of prevalent cardiovascular disease and risk factors. Results-Each measure of diastolic function was robustly associated with NT-proBNP and incident HF or death. ARIC-based ...
http://circ.ahajournals.org/content/early/2016/12/07/CIRCULATIONAHA.116.024825
Pioglitazone improves left ventricular diastolic function in subjects with diabetes<...Pioglitazone improves left ventricular diastolic function in subjects with diabetes<...
TY - JOUR. T1 - Pioglitazone improves left ventricular diastolic function in subjects with diabetes. AU - Clarke, Geoffrey D. AU - Solis-Herrera, Carolina. AU - Molina-Wilkins, Marjorie. AU - Martinez, Sandra. AU - Merovci, Aurora. AU - Cersosimo, Eugenio. AU - Chilton, Robert J. AU - Iozzo, Patricia. AU - Gastaldelli, Amalia. AU - Abdul-ghani, Muhammad A. AU - Defronzo, Ralph A. PY - 2017/11/1. Y1 - 2017/11/1. N2 - OBJECTIVE To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS Twelve subjectswith T2Dand 12with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and myocardial perfusion were measured with [18F]fluoro-2-deoxy-D-glucose and [15O]H2O positron emission tomography before and after 24 weeks of pioglitazone treatment.Myocardial function and transmitral early diastolic relation/atrial contraction (E/A) flow ratio were ...
https://scholars.uthscsa.edu/en/publications/pioglitazone-improves-left-ventricular-diastolic-function-in-subj
Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular...Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular...
Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: The LIFE study Academic Article ...
http://vivo.med.cornell.edu/display/pubid33748522726
Abstract 706: Transient Pseudorestrictive Pattern of Transmitral Doppler Flow Pattern in Patients with Paroxysmal Atrial...Abstract 706: Transient Pseudorestrictive Pattern of Transmitral Doppler Flow Pattern in Patients with Paroxysmal Atrial...
Standard pulsed Doppler indices are inadequate for assessment of LV relaxation in patients with atrial fibrillation (AF). On the other hand, peak diastolic mitral annulus velocities (Ea) and color M-mode Doppler propagation velocity of mitral inflow (Vp) have been reported as reliable determinants of LV relaxation in those patients. There have been few reports on alteration of LV relaxation during paroxysmal AF. Thirty patients with paroxysmal AF were enrolled in this study. Standard 2 dimensional, color flow Doppler, and tissue Doppler echocardiography were performed before, during AF, and after conversion of AF within 24 hours. LV relaxation was compared among three periods. Early diastolic velocity of TMF (E-wave) was increased, and deceleration time was shortened significantly during AF. Furthermore, systolic velocity of pulmonary vein flow was decreased, and diastolic velocity was increased significantly during AF. These parameters returned to the baseline level after conversion of AF. On ...
http://circ.ahajournals.org/content/118/Suppl_18/S_603.2
Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers - Full Text View -...Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers - Full Text View -...
Impairment of relaxation, the early phase of ventricular diastole is the first stage of heart diastolic dysfunction. Left ventricular diastolic function can be determined noninvasively by Echo- Doppler - derived mitral valve flow velocities. The addition of pulmonary venous flow pattern enables more accurate assessment of left ventricle diastolic function. The role of the right ventricle in haemodynamic function of the heart is now emphasized. The right ventricle diastolic function can be assess by recording the Doppler tricuspid valve flow pattern. Impaired LV diastolic function usually precedes systolic dysfunction and may cause clinical signs of congestive heart failure. Cigarette smoking is one of the major risk factors for cardiovascular diseases. The aim of the study was to assess left and right ventricular diastolic function in healthy, young and slim smokers before and after smoking one cigarette.. Echocardiographic examination: before and after smoking one cigarette Echocardiographic ...
https://clinicaltrials.gov/ct2/show/NCT00395928
HKU Scholars Hub: Hyperthyroidism-induced left ventricular diastolic dysfunction: Implication in hyperthyroidism-related heart...HKU Scholars Hub: Hyperthyroidism-induced left ventricular diastolic dysfunction: Implication in hyperthyroidism-related heart...
Summary Background Heart failure occurs in 6% of hyperthyroid patients. Nonetheless, only half of those with hyperthyroidism-related heart failure have impaired left ventricular (LV) systolic function. Thus, diastolic dysfunction may play an important role in the pathogenesis. Methods and results We performed serial echocardiographic examinations in 70 consecutive patients with hyperthyroidism (39 ± 2 years, 47 women) to determine their diastolic function and repeated the examinations 6 months after achieving a euthyroid state. All patients had normal LV systolic function, but diastolic dysfunction was detected in 22 cases (mild: 3, moderate: 15 and severe: 4). The prevalence of diastolic dysfunction increased with age from 17·9% in patients ,40 years to 100% in those ,60 years. Increasing age was the only independent predictor for diastolic dysfunction in hyperthyroid patients. After achievement of a euthyroid state, most patients (16/22, 72%) had completely normalized diastolic function: ...
http://hub.hku.hk/handle/10722/137416
Tissue Doppler indices of diastolic function in critically ill patients and association with mortality - a systematic review. -...
Systolic impairment is well reported in critically ill patients but diastolic function has been relatively understudied. The objective of this review was to assess tissue Doppler indices of diastolic function in critically ill patients along with any association with mortality.A systematic review of articles in English using Medline, EMBASE, CINAHL and the Cochrane database of systematic reviews. Search terms included diastolic function, diastolic dysfunction, diastolic abnormal*, diastolic heart failure, diastolic filling, ventricular relaxation, pulmonary artery occlusion pressure, left ventricular filling pressure, cardiac dysfunction, intensive care, critical care, critically ill, critical illness, sepsis and septic shock. Only studies of critically ill adult patients (excluding post-cardiac surgical patients) whose diastolic function was assessed using tissue Doppler imaging were included. Study quality was assessed using a modified version of the Newcastle-Ottawa Scale (NOS).Nineteen studies were
https://www.ndorms.ox.ac.uk/publications/607555
Complications of myocardial infarction - Cardiac OutputComplications of myocardial infarction - Cardiac Output
Early ventricular fibrillation is not related to infarct size. After 24 h ischemic myocytes have either undergone necrosis or recovered, and the risk of ventricular fibrillation diminishes. The majority of the other complications occur in transmural infarcts. Cardiogenic shock is directly related to the proportion of the left ventricular muscle mass which has been lost. Large infarcts are more likely to be anterior because the left anterior descending coronary aretery supplies more than 60 per cent of the myocardial mass.. Cardiogenic shock may lead to an extension of the area of necrosis ( Fig, 2). Myocardial perfusion is dependent on the relation between aortic diastolic pressure and left ventricular cavity pressure. If aortic pressure falls and left ventricular diastolic pressure rises, subendocardial perfusion throughout the whole left ventricle falls; a circumferential zone of subendocardial necrosis occurs and the centers of the papillary muscles also undergo necrosis ( Fig,... . . 2). ...
https://www.alpfmedical.info/cardiac-output/complications-of-myocardial-infarction.html
Nonalcoholic Steatohepatitis (NASH) Impairs Ventricular Diastolic Distensibility And Function Independent Of Underlying Type 2...Nonalcoholic Steatohepatitis (NASH) Impairs Ventricular Diastolic Distensibility And Function Independent Of Underlying Type 2...
We use cookies to ensure that we give you the best experience on our website. If you click Continue well assume that you are happy to receive all cookies and you wont see this message again. Click Find out more for information on how to change your cookie settings ...
https://www.rdm.ox.ac.uk/publications/738611
Glycosylated hemoglobin and left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus | International...
Conclusion: Our findings indicate that myocardial damage in patients with diabetes affects diastolic function before systolic function.Even young patients with diabetics with normal systolic ventricular function have diastolic dysfunction, which serves as a marker of a diabetic cardiomyopathy. Diastolic impairment seems not to correlate with disease duration. HbA1c% can be a very good indicator of long term prognosis. Strong correlation exist between diastolic dysfunction and HbA1c%.. ...
http://recentscientific.com/glycosylated-hemoglobin-and-left-ventricular-diastolic-dysfunction-patients-type-2-diabetes-mellitus
Diastolic Stress Test | JACC: Cardiovascular ImagingDiastolic Stress Test | JACC: Cardiovascular Imaging
Diastolic dysfunction is a key factor in the pathogenesis of heart failure. Around 50% of cases of heart failure, the hemodynamic correlate of which is increased left ventricular filling pressure, are caused by diastolic dysfunction in the setting of apparently normal systolic function. Due to its high prevalence, diastolic dysfunction is often recognized as an incidental finding. Many patients have Doppler echocardiographic evidence of impaired diastolic function but do not have any symptoms of heart failure at rest. In many of these patients, symptoms of diastolic dysfunction occur only during exercise, as left ventricular filling pressure is normal at rest, but increases with exercise. This implies that filling pressures should also be measured during exercise. The diastolic stress test refers to the evaluation of diastolic function, either invasively or noninvasively, during exercise. This review focuses on the clinical need for diastolic stress testing, both invasively and noninvasively. ...
https://imaging.onlinejacc.org/content/13/1_Part_2/272
Sustained left ventricular diastolic dysfunction after exercise in patients with dilated cardiomyopathy | HeartSustained left ventricular diastolic dysfunction after exercise in patients with dilated cardiomyopathy | Heart
Although the exercise test was performed after diagnostic catheterisation after an interval of more than three days, non-specific effects of catheterisation and contrast medium might modify postexercise diastolic function. However, the interval between the diagnostic catheterisation and exercise test did not differ significantly among the groups (table 1). Thus the postexercise diastolic dysfunction in group 1 could not be attributed to the effect of catheterisation.. We performed echocardiography serially over a seven day period after exercise. Therefore it is possible that postexercise changes in Doppler indices in patients with dilated cardiomyopathy were a result of measurement errors or day to day variability. However, the mitral flow velocity profile was unchanged throughout the study in the normal subjects and in the dilated cardiomyopathy patients in group 2. Thus day to day variability of Doppler measurements were minimal. Bias related to echocardiographic analysis was also excluded, as ...
http://heart.bmj.com/content/80/3/263
The Pathophysiology of Heart Failure With Normal Ejection Fraction | JACC: Journal of the American College of CardiologyThe Pathophysiology of Heart Failure With Normal Ejection Fraction | JACC: Journal of the American College of Cardiology
In this study, we have performed a comprehensive assessment of systolic and diastolic ventricular function with new noninvasive techniques at rest and on exercise in HFNEF patients and have demonstrated a variety of abnormalities of both systolic and diastolic function. These include reduced radial and longitudinal myocardial systolic strain both at rest and on exercise, reduced systolic and diastolic longitudinal functional reserve (mitral annular velocities fail to rise normally), reduced ventricular systolic rotation at rest that fails to increase normally on exercise, delayed ventricular untwisting with further worsening on exercise associated with a reduced LV suction, and a consequent reduced stroke volume rise on exercise. Recent studies (12-14,37) using similar echocardiographic techniques to ours have elegantly demonstrated the close temporal, functional, and tightly coordinated relationships in normal patients between LV twist during systole, with accompanying mitral annular motion ...
http://www.onlinejacc.org/content/54/1/36?ijkey=29b3f4f69fb30f22d6858e462e244957cf980a1e&keytype2=tf_ipsecsha
Diastolic dysfunction was predictive of all cause mortality | Evidence-Based MedicineDiastolic dysfunction was predictive of all cause mortality | Evidence-Based Medicine
The study by Redfield et al lends further support to the concept that diastolic dysfunction is prevalent, causes symptoms of CHF, and is associated with increased mortality. Diastolic dysfunction refers to a pathologically non-compliant left ventricle (LV) in diastole, which is the result of the combination of slowed LV relaxation and increased stiffness caused by hypertension, diabetes, ischaemia, or a combination.1. The study uses a model of diastolic dysfunction that assumes temporal progression of dysfunction from mild to moderate to severe based on left heart filling patterns obtained by state of the art echo Doppler techniques. Some aspects of this approach are problematic. The temporal progression of diastolic dysfunction has not been shown, the use of echo Doppler parameters was obtained at only a single point in time, and the use of these filling patterns to reflect LV properties in a wide range of patients is not the standard of measurement. Although these limitations should be ...
http://ebm.bmj.com/content/8/5/157
Isolated Left Ventricular Filling Abnormalities May Predict Interleukin-2-Induced Cardiovascular Toxicity<...
TY - JOUR. T1 - Isolated Left Ventricular Filling Abnormalities May Predict Interleukin-2-Induced Cardiovascular Toxicity. AU - Citterio, G.. AU - Fragasso, G.. AU - Rossetti, E.. AU - Di Lucca, G.. AU - Bucci, E.. AU - Foppoli, M.. AU - Guerrieri, R.. AU - Matteucci, P.. AU - Polastri, D.. AU - Scaglietti, U.. AU - Tresoldi, M.. AU - Chierchia, S. L.. AU - Rugarli, C.. PY - 1996. Y1 - 1996. N2 - Interleukin-2 (IL-2) is a cytokine with proven activity against metastatic renal cell carcinoma (RCC) and malignant melanoma (MM). The intravenous administration of high-dose IL-2 is limited by important cardiovascular side effects such as hypotension, fluid retention, arrhythmias, and myocardial chemia, which often cause dose reduction and/or treatment withdrawal. The occurrence of these toxic events is not predicted by routine pretreatment examinations. The aim of the present study was to test the reliability of serial echocardiography in predicting subsequent cardiac adverse effects in patients ...
https://moh-it.pure.elsevier.com/en/publications/isolated-left-ventricular-filling-abnormalities-may-predict-inter
Russian Heart Failure Journal 2005year Diastolic dysfunction of left and right ventricles and possibilities for its correction...
The LV and right ventricular (RV) diastolic function was evaluated in 65 patients with degree II arterial hypertension (AH) (WHO/IAH?, mean age 50.6±1.2 years) using Doppler echoCG at rest and in cold stress. The study demonstrated a possibility for asynchronous development of ventricular diastolic dysfunction with its prevalence of 14.7% for LV and 23.5% for RV. Disorders of both LV and RV diastolic function were revealed in 26.5% of patients. The cold test considerably more frequently induced impairment of RV than LV diastolic function. Both LV and RV diastolic dysfunction can be sufficiently well corrected with lisinopril, nebivolol and amlodipine ...
http://lib.rushf.org/journals/RHFJ/2005/diastolicheskaya-disfunktsiya-levogo-i-pravogo-zheludochka-u-bolnykh-arterialnoy-gipertoniey-i-vozmo/
Insulin resistance and glycemic abnormalities are associated with deterioration of left ventricular diastolic function: a cross...Insulin resistance and glycemic abnormalities are associated with deterioration of left ventricular diastolic function: a cross...
The main finding of the present study is that IR is associated with LVDD independent of overt diabetes. These finding persist after adjustment for CAD, hypertension, age, sex, history of previous myocardial infarction, history of previous coronary angioplasty, EF and glycaemic control. To our knowledge, this is the first study that demonstrated an association in a population of patients without a history of diabetes focusing on the published current guidelines for the diagnosis of LVDD.. Furthermore, our date confirm the observations that T2DM is associated with LVDD [9], which is considered a precursor of diabetic cardiomyopathy. In addition, we were able to extend the findings in previous studies showing the association between LVDD and IGT.. These findings are in line with a limited number of studies that assessed the relationship between prediabetes and LVDD mainly in population based studies [11]. Nevertheless, there are some concerns about methodological issues involving the identification ...
https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-9-63
Role of Diastole in Left Ventricular Function, I: Biochemical and Biomechanical Events | American Journal of Critical Care |...Role of Diastole in Left Ventricular Function, I: Biochemical and Biomechanical Events | American Journal of Critical Care |...
Left ventricular diastolic function plays an important role in cardiac physiology. Lusitropy, the ability of the cardiac myocytes to relax, is affected by both biochemical events within the myocyte and biomechanical events in the left ventricle. β-Adrenergic stimulation alters diastole by enhancing the phosphorylation of phospholamban, a substrate within the myocyte that increases the uptake of calcium ions into the sarcoplasmic reticulum, increasing the rate of relaxation. Troponin I, a regulatory protein involved in the coupling of excitation to contraction, is vital to maintaining the diastolic state; depletion of troponin I can produce diastolic dysfunction. Other biochemical events, such as defects in the voltage-sensitive release mechanism or in inositol triphosphate calcium release channels, have also been implicated in altering diastolic tone. Extracellular collagen determines myocardial stiffness; impaired glucose tolerance can induce an increase in collagen cross-linking and lead to ...
https://aacnjournals.org/ajcconline/article-abstract/13/5/394/316/Role-of-Diastole-in-Left-Ventricular-Function-I
The participants were randomly assigned to receive the usual prim | Thrombin Inhibitors
The participants were randomly assigned to receive the usual primary care (control condition; n = 677) or screening with BNP testing (n = 697) and followed up until December 2011 (mean follow-up, 4.2 [SD, 1.2] years). Intervention-group participants, with BNP levels of 50 pg/mL Sirtinol clinical trial or higher, underwent. echocardiography and collaborative care between their primary care physician and specialist cardiovascular service. The primary end point was prevalence of asymptomatic systolic LV dysfunction, with or without newly diagnosed heart failure. Due to the slower than expected recruitment rates, the investigators extended the study period and redefined the primary endpoint to include significant LV diastolic dysfunction as determined by a ratio of mitral peak velocity. of early filling (E) to early diastolic mitral annular velocity (E) greater than 15.It is important to note that this change did not alter the validity of the study design. Secondary end points included emergency ...
http://thrombininhibitors.com/the-participants-were-randomly-assigned-to-receive-the-usual-prim
Plus itPlus it
This study, conducted in a cohort of never-treated and well-characterized hypertensive patients, showed that the worsening of glucose tolerance was associated with an impairment of left ventricular diastolic function. The main finding of this study is that 1-h postload plasma glucose in NGT subjects is associated with left ventricular diastolic dysfunction. This result persists after adjustment for all significant covariates reported in Table 3. Of interest and clinically relevant, NGT ≥155 subjects had significantly worse diastolic function compared with NGT,155 subjects and similar compared with IGT and T2D patients. To our knowledge, this is the first study that demonstrates this association, confirming the usefulness of early diagnosis in the stratification of overall cardiovascular risk; in addition, it highlights the links between early alterations of glucose tolerance and early alterations in cardiac function.. There is a consistent body of evidences demonstrating the association ...
http://care.diabetesjournals.org/content/34/10/2291
Plus itPlus it
Abstract Cardiovascular autonomic neuropathy (CAN) is one of the most serious complications of diabetes and has been weakly linked with left ventricular (LV) diastolic dysfunction. Previous studies that explored this association either suffer from inadequate definition of CAN or have mainly used conventional Doppler or nuclear techniques to investigate LV diastolic function. Tissue Doppler imaging (TDI) has evolved as a new quantitative tool for the assessment of cardiac systolic function, diastolic function, and the hemodynamics of LV filling. We sought to investigate conventional and TDI derived indices of LV systolic and diastolic function in type 1 patients with and without CAN, and also in normal control subjects. Our findings suggest that the presence of CAN seems to have an additive effect on LV diastolic dysfunction in type 1 diabetes.. ...
http://care.diabetesjournals.org/content/early/2007/11/13/dc07-1634
OpenEmory | Search ResultsOpenEmory | Search Results
Background: Patients with coronary microvascular dysfunction (CMD) often have diastolic dysfunction, representing an important therapeutic target. Ranolazine-a late sodium current inhibitor-improves diastolic function in animal models and subjects with obstructive coronary artery disease (CAD). Hypothesis: We hypothesized that ranolazine would beneficially alter diastolic function in CMD. Methods: To test this hypothesis, we performed retrospective tissue tracking analysis to evaluate systolic/diastolic strain, using cardiac magnetic resonance imaging cine images acquired in a recently completed, randomized, double-blind, placebo-controlled, crossover trial of short-term ranolazine in subjects with CMD and from 43 healthy reference controls. Results: Diastolic strain rate was impaired in CMD vs controls (circumferential diastolic strain rate: 99.9% ± 2.5%/s vs 120.1% ± 4.0%/s, P = 0.0003; radial diastolic strain rate: −199.5% ± 5.5%/s vs −243.1% ± 9.6%/s, P = 0.0008, case vs control). ...
https://open.library.emory.edu/publications/search/?keywords=control&keywords=eject&subject=Biology%2C+Physiology&keywords=cardiac
Predictors of subclinical diastolic dysfunction measured by MRI: multi-ethnic study of atherosclerosis (MESA) | Journal of...Predictors of subclinical diastolic dysfunction measured by MRI: multi-ethnic study of atherosclerosis (MESA) | Journal of...
Table 1 illustrates associations between risk factors with diastolic LV function. End diastolic volume (EDV) modified the relationship of gender and PFR. Mean PFR was therefore analyzed across quintiles of EDV and was found to be higher in females 386.35, [95%CI 382.53 to 390.17] compared to males 359.11 ml/s [95%CI 355.05 to 363.17] (Fig 1). Comapred to non-smokers smokers had lower peak filling rates. Compared to Whites, Hispanics were at a higher risk for diastolic dysfunction, Chinese ethnicity showed a relative protective effect after adjusting for all other risk factors. ...
https://jcmr-online.biomedcentral.com/articles/10.1186/1532-429X-11-S1-O15
Evolution and outcome of diastolic dysfunction | HeartEvolution and outcome of diastolic dysfunction | Heart
The division of diastolic dysfunction into three classes implies progression from one class to the next. However, to our knowledge, no previous studies have shown such progression to occur and the factors that influence this progression. In the current study, over 3.6 years, diastolic function remained stable in approximately half of the study population. Of the remainder, diastolic function deteriorated in 27% and improved in 21%. This suggests that in about half of these patients, diastolic function does not progress with time and the division into stages or classes of severity may erroneously suggest that progression naturally occurs from one stage to the next. From the multivariate model of the predictors of all-cause mortality, progression of diastolic dysfunction, age, clinical evidence of heart failure at the time of echocardiogram, the presence of a major co-morbidity, transmitral flow and diuretic use were each independently associated with outcome. Importantly, the subgroup of patients ...
http://heart.bmj.com/content/95/10/813
Diagnosing Left Ventricular Diastolic Dysfunction by Echocardiography : Reverend Bayes Lends a HandDiagnosing Left Ventricular Diastolic Dysfunction by Echocardiography : Reverend Bayes Lends a Hand
2010 (English)In: Journal of the American Society of Echocardiography, ISSN 0894-7317, E-ISSN 1097-6795, Vol. 23, no 2, 162-163 p.Article in journal (Other academic) Published ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:383388
Dyspnea and normal systolic function]. - MyScienceWorkDyspnea and normal systolic function]. - MyScienceWork
[Dyspnea and normal systolic function].: 30-50% of patients presenting with symptoms of congestive heart failure exhibit a near normal left ventricular systolic
https://www.mysciencework.com/publication/show/dyspnea-normal-systolic-function-28b38f26
Increased Systolic Performance With Diastolic Dysfunction in Adult Spontaneously Hypertensive Rats | HypertensionIncreased Systolic Performance With Diastolic Dysfunction in Adult Spontaneously Hypertensive Rats | Hypertension
To our knowledge, this is the first study comparing the contractile function in SHR with its normotensive control WKY using PV methodology. In addition, we assessed diastolic function in these animals by using this technique and two others. PV analysis is a useful approach for examining the intact chamber function independently of load.. Diastolic dysfunction was expected in the SHR, based on the increased wall thickness and fibrosis and the impaired relaxation and augmented chamber stiffness reported by others using this model.1,4,29 These alterations were detected in vivo in our study, based on the increased EDPVR, the restrictive pattern of the Doppler E/A ratio, and the leftward shift in the PV relation observed in the ex vivo experiments. Impaired relaxation was also detected in our hypertensive animals, as reflected by the prolonged τ and the fact that for a given maximal velocity of contraction (+dP/dt), maximal velocity of relaxation (−dP/dt) was decreased. Relaxation, an active ...
http://hyper.ahajournals.org/content/41/2/249
What parameters affect left ventricular diastolic flow propagation velocity? in vitro studies using color m-mode doppler...What parameters affect left ventricular diastolic flow propagation velocity? in vitro studies using color m-mode doppler...
Insufficient data describe the relationship of hemodynamic parameters to left ventricular (LV) diastolic flow propagation velocity (Vp) measured using color M-mode Doppler echocardiography.. Go to the Article ...
https://vivitrolabs.com/company/cited-publications/what-parameters-affect-left-ventricular-diastolic-flow-propagation-velocity-in-vitro-studies-using-color-m-mode-doppler-echocardiography/
Mechanism of Abnormal JVF Patterns and Jugular Pulse Contours in Restriction to Ventricular Filling - Cardiac Physical...Mechanism of Abnormal JVF Patterns and Jugular Pulse Contours in Restriction to Ventricular Filling - Cardiac Physical...
Fig. 21. The varying severity of restriction to diastolic ventricular filling is shown with lines to indicate the ventricular diastolic pressure elevations and their timing in diastole. In mild form, the pressure increase is during atrial contraction (AC) at end diastole (line #1). As restriction gets worse, the pre-a wave pressure starts to rise gradually and earlier and earlier in diastole. This progression is shown as four successive lines (lines #2). When severe, it may be total during mid and late diastole, restricting flow into the RV beginning with the slow filling phase (SF). There will be very rapid inflow only during early diastole or the rapid filling phase (RF) followed by a rapid rise in pressure with no further flow producing the classic dip and plateau or the square root pattern (line #3). This is typical for chronic constrictive pericarditis. If the restriction is severe and involves also the RF phase, the pressures rise quickly in the RV in early diastole limiting inflow ...
https://www.mitchmedical.us/cardiac-physical-examination/mechanism-of-abnormal-jvf-patterns-and-jugular-pulse-contours-in-restriction-to-ventricular-filling.html
Heart diastolic dysfunction || blog.manicurex.ru
While diastolic heart failure refers to the clinical syndrome of heart failure in the setting of a normal ejection fraction. Diagnosis, prognosis. Diastolic dysfunction. Quence of diastolic dysfunction. Heart diastolic dysfunction diastolic heart failure, a major cause of morbidity and mortality, is defined as symptoms of heart failure in a patient with preserved left ventricular function. Recommendations for the Evaluation of Left Ventricular. Patients with diastolic heart failure, as well as those with diastolic dysfunction and little or no congestion, exhibit exercise intolerance for two principal reasons. New concepts in diastolic dysfunction and diastolic heart failure. Diastolic Function by Echocardiography. ...
http://blog.manicurex.ru/appomneau/heart-diastolic-dysfunction7481.php
PRIME PubMed | Right ventricular diastolic function 15 to 35 years after repair of tetralogy of Fallot. Restrictive physiology...PRIME PubMed | Right ventricular diastolic function 15 to 35 years after repair of tetralogy of Fallot. Restrictive physiology...
PubMed journal article: Right ventricular diastolic function 15 to 35 years after repair of tetralogy of Fallot. Restrictive physiology predicts superior exercise performance. Download Prime PubMed App to iPhone, iPad, or Android
https://www.unboundmedicine.com/medline/citation/7882487/Right_ventricular_diastolic_function_15_to_35_years_after_repair_of_tetralogy_of_Fallot__Restrictive_physiology_predicts_superior_exercise_performance_
Russian Heart Failure Journal 2008year Left ventricle diastolic function in patients with sick sinus syndrome
Urgency. In patients with sick sinus syndrome (SSS), symptoms of heart failure result from pronounced bradycardia and the failure to increase sinus rhythm adequately during exercise. Aim. Evaluating parameters of LV diastolic function in patients with SSS before and after the surgery of electric cardiostimulator (ECS) implantation. Materials and methods. Study enrolled 37 patients with SSS who were randomized to three groups: group 1, patients with type 1 LV diastolic dysfunction (DD); group 2, patients with type 2 LV DD; group 3, patients without LV DD. EchoCG was performed before and after ECS implantation. Results. The ECS implantation improved LV diastolic function in patients with type LV DD. The ECS implantation did not influence the LV diastolic function in patients with SS in advanced type 2 LV DD or with normal LV diastolic function ...
http://lib.rushf.org/journals/RHFJ/2008/912/
Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study | Clinical Research...Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study | Clinical Research...
Clinical trial for NIDDM , Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study
https://www.centerwatch.com/clinical-trials/listings/211196/diabetes-mellitus-type-2-teneligliptin-on-progressive-left/
Effect of ischemic arrest on left ventricular relaxation, diastolic stiffness and contractility<...
TY - JOUR. T1 - Effect of ischemic arrest on left ventricular relaxation, diastolic stiffness and contractility. AU - Schaff, Hartzell V. AU - Flaherty, J. T.. AU - Fredricksen, J. W.. PY - 1977. Y1 - 1977. N2 - The effect of ischemic arrest (IA) on ventricular relaxation and the diastolic pressure-volume (P/V) relationship was studied in 17 isolated, perfused, isovolumic feline hearts. During one hour of IA, nine hearts were maintained at normothermia (NIA) and eight were cooled to 27°C hypothermia (HIA). Maximum dP/dt was used as an index of contractility. P/V curves were inscribed by constant volume infusion into an intraventricular balloon and plotted according to the equation Pd = βe (dVd), where Pd = end diastolic pressure; Vd = end diastolic volume; (stiffnes constant) = slope of in Pvs Vd; and β = InP intercept at Vd = 0. To normalize for initial cavity size, curves were replotted as Pd vs (Vd-Vo)/V0, where Vo = volume at Pd of 10 mm Hg. Left ventricular relaxation was assessed by ...
https://mayoclinic.pure.elsevier.com/en/publications/effect-of-ischemic-arrest-on-left-ventricular-relaxation-diastoli
Prognostic significance of left ventricular diastolic dysfunction in patients with left ventricular hypertrophy and systemic...
Patients with hypertension and left ventricular (LV) hypertrophy commonly have impaired diastolic filling. However, it remains unknown whether changes in LV diastolic filling variables are associated with cardiovascular morbidity and mortality. In this study, 778 patients with hypertension with electrocardiographic LV hypertrophy who underwent echocardiography at baseline and annually thereafter during randomized losartan- or atenolol-based antihypertensive treatment were followed for a mean of 4.6 years. The composite cardiovascular end point was the first occurrence of fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, and cardiovascular mortality. Antihypertensive therapy resulted in an increase in the prevalence of normal transmitral flow pattern from 28% to 46% of patients. Although antihypertensive treatment often resulted in a marked increase in the prevalence of normal mitral valve flow pattern, this was not associated with reduced cardiovascular morbidity and mortality ...
https://research.regionh.dk/rigshospitalet/en/publications/prognostic-significance-of-left-ventricular-diastolic-dysfunction-in-patients-with-left-ventricular-hypertrophy-and-systemic-hypertension-the-life-study
Pressure-Volume with Medical Diagnostic Ultrasound Imaging - Patent applicationPressure-Volume with Medical Diagnostic Ultrasound Imaging - Patent application
0068] In act 48, a value for a parameter is output. This value is another example of the output of act 44. The value is derived from the pressure and/or volume information, either instantaneous or as a function of time. For example, beat-to-beat parameters, such as stroke volume (SV), contractility (e.g., ejection fraction, SV/EDV, and/or dp/dt Max), preload (EDV or EDP), afterload (aortic and ventricular pressure), compliance (dV/dP), ventricular stiffness (inverse of compliance), and/or elastance (dP/dV), are calculated. As another example, parameters derived from ESPVR and EDPVR, such as PVA Pressure-volume area and/or PE Potential energy, are calculated. In yet another example, processed parameters, such as ESPVR end-systolic pressure-volume relationship, EDPVR end-diastolic pressure-volume relationship, PRSW Preload-recruitable stroke work, DPdtmax vs Ved dPdt max against end-diastolic volume relationship, and/or Emax maximal elastance (computed from the time-varying elastance data), are ...
http://www.patentsencyclopedia.com/app/20130245441
Effects of catecholamine stress on diastolic function and myocardial energetics in obesity. - Department of Physiology, Anatomy...
BACKGROUND: Obesity is characterized by impaired cardiac energetics, which may play a role in the development of diastolic dysfunction and inappropriate shortness of breath. We assessed whether, in obesity, derangement of energetics and diastolic function is further altered during acute cardiac stress. METHODS AND RESULTS: Normal-weight (body mass index, 22±2 kg/m(2); n=9-17) and obese (body mass index, 39±7 kg/m(2); n=17-46) subjects underwent assessment of diastolic left ventricular function (cine magnetic resonance imaging volume-time curve analysis) and cardiac energetics (phosphocreatine/ATP ratio; (31)P-magnetic resonance spectroscopy) at rest and during dobutamine stress (heart rate increase, 65±22% and 69±14%, respectively; P=0.61). At rest, obesity was associated with a 22% lower peak filling rate (P|0.001) and a 15% lower phosphocreatine/ATP ratio (1.73±0.40 versus 2.03±0.28; P=0.048). Peak filling rate correlated with fat mass, left ventricular mass, leptin, waist-to-hip ratio, and
https://www.dpag.ox.ac.uk/publications/312942
Pseudonormalization definition | Drugs.comPseudonormalization definition | Drugs.com
Definition of pseudonormalization. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
https://www.drugs.com/dict/pseudonormalization.html
Chronic systemic inflammation accompanies impaired ventricular diastolic function, detected by Doppler imaging, in patients...Chronic systemic inflammation accompanies impaired ventricular diastolic function, detected by Doppler imaging, in patients...
We sought to evaluate the relationship between plasma cytokine levels (sCD14, tumor necrosis factor [TNF]-alpha, and interleukin [IL]-6) and tissue Doppler derived indices of left ventricular systolic and diastolic function in patients with newly diagnosed heart failure. We enrolled 101 consecutive patients (mean age 65+/-13 years) with newly diagnosed heart failure who were hospitalized in our institute. Echocardiographic assessment was performed in all patients during the third day of their initial hospitalization. The pulsed tissue Doppler imaging (TDI) of the systolic and diastolic function of mitral annulus was characterized by the systolic wave Smv, and the diastolic waves: Emv and Amv. Left atrial kinetic energy (LAKE), an index of left atrial function, was calculated using the equation 1/2 x LASV x 1.06 x Amv(2); where LASV is left atrial systolic volume. Furthermore the ratio E/Emv and the flow propagation velocity were also calculated; where E is the rapid mitral filling wave, detected ...
https://scholars.latrobe.edu.au/display/publication502274
I have bicuspid aortic valve mild AR mildAs with mild lv diastolic dysfunction. I am ta...I have bicuspid aortic valve mild AR mildAs with mild lv diastolic dysfunction. I am ta...
I have bicuspid aortic valve mild AR mildAs with mild lv diastolic dysfunction. I am taking embeta xr 75 mg in a day for arrythemia. Please give me suggestions.
https://www.lybrate.com/question/1391731353/hv-bicuspid-aortic-valve-mild-ar-mildas-mild-lv-diastolic-dysfunction-taking-embeta-xr-75-mg-arrythemia-suggestions?lpt=PS-CPV
Preoperative tissue Doppler imaging and diastolic filling patterns on postoperative new-onset atrial fibrillation in...Preoperative tissue Doppler imaging and diastolic filling patterns on postoperative new-onset atrial fibrillation in...
Citation counts are provided from Web of Science and CrossRef. The counts may vary by service, and are reliant on the availability of their data. Counts will update daily once available.. ...
https://ccforum.biomedcentral.com/articles/10.1186/cc6472/metrics
Most recent papers with the keyword doppler echo to measure lv filling pressures | Read by QxMDMost recent papers with the keyword doppler echo to measure lv filling pressures | Read by QxMD
We investigated the impact of lowering blood pressure (BP) with azelnidipine, a newly developed calcium channel blocker, generation on the left ventricular (LV) diastolic function and LV filling pressure by assessing non-invasive indices derived from echo Doppler study. This study evaluated 232 hypertensive patients with diastolic dysfunction. This study had two groups: (1) in which azelnidipine was administered to patients as a first-line therapy, and (2) in which amlodipine was converted to azelnidipine. Early diastolic mitral annulus velocity (e, cm s(-1)), the ratio of peak E velocity to e velocity (E/e ratio) and level of brain natriuretic peptide (BNP) were measured before and, an average of, 8 months after azelnidipine treatment ...
https://www.readbyqxmd.com/keyword/51359
Left ventricular diastolic dysfunction is associated with cerebral infarction in young hypertensive patients: A retrospective...Left ventricular diastolic dysfunction is associated with cerebral infarction in young hypertensive patients: A retrospective...
Young ischemic stroke (YIS) refers to ischemic stroke occurring in patients aged 45 or under and its incidence is increasing annually (14). The reason is probably its characteristics of early onset, early disability and high recurrence. At present, YIS accounts for an estimated 5-10% of all cases of CI and the most common pathogenetic origin of the disease is atherosclerosis caused by hypertension (21). The pathogenic effect of hypertension has been indicated to be directly correlated with its severity and duration, which indicates a connection between hypertension and an increased risk of YIS (22).. Young patients pay insufficient attention to blood pressure and frequently remain untreated (23). This long-term elevation of peripheral blood pressure increases cardiac after-loading, while increased peripheral vasoconstriction tension and retention of sodium and water increase myocardial oxygen consumption, deteriorate myocardial compliance and augment ventricular end-diastolic pressure (24). As a ...
https://www.spandidos-publications.com/10.3892/etm.2020.9189?text=fulltext
Plus itPlus it
Background: Systolic heart failure (HF) is frequently accompanied by diastolic dysfunction and sleep-disordered breathing (SDB). We evaluated, whether auto-servo ventilation (ASV, BiPAP ASV, Philips Respironics) improves echocardiographic measures of diastolic function in patients with systolic HF and SDB.. Methods: 32 patients with stable systolic HF and concomitant diastolic dysfunction (age 66±9y, LVEF 30±7%, NYHA class II 72%) and SDB (AHI 48±19/h, 53% OSA) were randomized to either ASV (n=19) or optimal medical treatment alone (control, n=13). Polysomnography and echocardiography was performed at baseline and after 12 weeks.. Results: AHI improved significantly more in the ASV group compared to the control group (-38±18 vs. -0.2±13.2/h, P,0.001). At baseline, 24 (75%) patients had impaired left ventricular relaxation, and 8 (25%) had a pseudonormalized filling pattern. At the 12-weeks control visit, diastolic function as assessed by the isovolumetric relaxation time (IVRT, -10.3±26.1 ...
http://erj.ersjournals.com/content/40/Suppl_56/P881
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Left ventricular diastolic dysfunction is highly prevalent, tends to worsen over time, and is associated with advancing age. Worsening diastolic function can be detected even in apparently healthy persons, the conclusion by the authors of a recent article published in JAMA.. Randomly selected participants 45 years or older (N = 2042) underwent clinical evaluation, medical record abstraction, and echocardiography (examination 1 [1997-2000]). Diastolic left ventricular function was graded as normal, mild, moderate, or severe by validated Doppler techniques. After 4 years, participants were invited to return for examination 2 (2001-2004). The cohort of participants returning for examination 2 (n = 1402 of 1960 surviving [72%]) then underwent follow-up for ascertainment of new-onset heart failure (2004-2010).. During the 4 years between examinations, diastolic dysfunction prevalence increased from 23.8% to 39.2%:. ...
https://www.cardiachealth.org/diastolic-dysfunction-and-risk-of-heart-failure/
type 2 diabetes - liver and coronary heart ailment in diabetic issues [Aditi Kothiyal]
Nonalcoholic fatty liver illness (NAFLD) can be a issue [[http://​robertfkennedyjr.net/​form-two-diabetes-induce-and-remedy/​,http://​www.diettalk.com]] ​ wherein the liver has as well substantially unwanted fat. Commonly it can be not deadly, but it surely may become infected. In nondiabetics it has been related to a heart disorder regarded as left ventricular diastolic dysfunction. The remaining ventricle on the heart pumps blood coming from the lungs via the still left atrium. Blood pumped through the remaining ventricle travels in the aorta, a big artery, from where by it travels throughout the body. In left ventricular diastolic dysfunction,​ LVDD, the left ventricle does not fill thoroughly involving beats. This may trigger fluid to again up in the still left atrium together with the lungs. This problem is known as heart failure. Investigators at College and Azienda Ospedaliera Universitaria Integrata of Verona and other investigate centers in Italy, executed a examine to ...
http://www.et.iitb.ac.in/~aditi/doku.php?id=type_2_diabetes_-_liver_and_coronary_heart_ailment_in_diabetic_issues&rev=1444730631&do=diff
Predictors of early cardiac changes in patients with type 1 diabetes mellitus: An echocardiography-based study | Bosnian...Predictors of early cardiac changes in patients with type 1 diabetes mellitus: An echocardiography-based study | Bosnian...
In patients with type 1 diabetes mellitus (T1DM) imaging studies have demonstrated an increased prevalence of left ventricular diastolic dysfunction and increased left ventricular mass (LVM) unrelated to arterial hypertension and ischemic heart disease. The aim of our study was to identify potential predictors of early subclinical changes in cardiac chamber size and function in such patients. Sixty-one middle-aged asymptomatic normotensive patients with T1DM were included in the study. Conventional and tissue Doppler echocardiography was performed and fasting serum levels of glucose, glycated hemoglobin (HbA1c), lipids, and creatinine were measured. We found moderate bivariate correlations of body mass index (BMI) with left atrial volume (r = 0.47, p , 0.01), LVM (r = 0.42, p , 0.01), left ventricular relative wall thickness (r = 0.32, p = 0.01), and all observed parameters of diastolic function of both ventricles. The five-year average value of HbA1c weakly correlated with the Doppler index of ...
https://bjbms.org/ojs/index.php/bjbms/article/view/4250
Diagnostic Criteria for Diastolic Heart Failure - MedicalCRITERIA.comDiagnostic Criteria for Diastolic Heart Failure - MedicalCRITERIA.com
Clinical symptoms and signs, supporting chest radiography, typical clinical response to diuretics with or without elevated left ventricular filling pressure, or low cardiac index.. ‡- Left ventricular ejection fraction of 50 percent or more within 72 hours of event.. §- Abnormal left ventricular relaxation or filling or distensibility indices on catheterization.. References:. ...
https://medicalcriteria.com/web/cardiastolic/
Improved Diastolic Function Is Associated With Higher Cardiac Output in Patients With Heart Failure Irrespective of Left...Improved Diastolic Function Is Associated With Higher Cardiac Output in Patients With Heart Failure Irrespective of Left...
Diastolic dysfunction, which is the key pathophysiological mechanism in HFpEF, is also considered a potential pathophysiological factor of HFrEF.23 In the present study, EDPVR normalization was significantly associated with higher CO regardless of EF in high‐EDP patients. Furthermore, there were no differences in the degree of change in CO among EF groups, suggesting that diastolic dysfunction exerts a similar hemodynamic effect regardless of EF. Although several previous articles have mentioned the importance of diastolic dysfunction in HFrEF,24, 25 this study is the first to demonstrate its quantitative impact on CO. This finding highlights the profound impact of diastolic dysfunction on hemodynamics in patients with HFrEF.. Previous studies26, 27 used the same single‐point EDPVR estimation method as we used in the current study. In those studies, α and β were defined as the diastolic curve fitting constant and stiffness constant, respectively. Those studies reported that the both α and ...
http://jaha.ahajournals.org/content/6/3/e003389
Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction - Danish...Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction - Danish...
Diastolic dysfunction is frequently seen after myocardial infarction and is characterized by a disproportionate increase in filling pressure during exercise to maintain stroke volume. We hypothesized that sildenafil would reduce filling pressure during exercise in patients with diastolic dysfunction after myocardial infarction ...
http://www.forskningsdatabasen.dk/catalog/239882222
Is it best to reFOCUS on basic echocardiography in the emergency department? | The Ultrasound Journal | Full TextIs it best to reFOCUS on basic echocardiography in the emergency department? | The Ultrasound Journal | Full Text
We read the article of Betcher et al. [1] regarding the feasibility of measuring stroke volume and diastolic function parameters with transthoracic echocardiography (TTE) in the emergency department (ED). While this is clearly stated as a feasibility study, we are honestly questioning the real utility of taking all these measurements, since nearly all patients can be managed without this information on the trenches, reasoning basic echo findings in context with the history and physician examination, without the need of adding complexity, spending extra time, or exposing patients to technique errors or interpretation mistakes. Mentors and trainees must understand (and thus focus on setting the bases of training accordingly) that a well-performed basic echocardiogram (with the addition of the information provided by lung ultrasound, which provides valuable data when showing the mere presence of B lines and/or pleural effusions, answering a simple clinical question in terms of wet vs. dry lungs ...
https://theultrasoundjournal.springeropen.com/articles/10.1186/s13089-018-0102-7
Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with...Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with...
Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein.
https://scholars.duke.edu/display/pub673407
Welcome To IndiaHeartBeat.Com Indias Leading Online Doctor Directory, Live HelpWelcome To IndiaHeartBeat.Com Indias Leading Online Doctor Directory, Live Help
Each heartbeat has a systolic component and a diastolic component. The heart first contracts and pumps blood out of the ventricular chambers (Systolic phase) and then goes through a phase of relaxation which allows blood to refill the ventricles (Diastolic Phase). According to this report, even when the systolic function is normal, diastolic dysfunction (DD) has been associated with an increased risk of death from cardiovascular and other reasons. The researchers in this study attempted to determine if the mortality risk associated with DD was an independent risk factor for increased risk for death in the presence of a normal systolic function. They also set out to determine whether this held true for milder cases of DD as well. The researchers began to understand the clinical relevance of the presence of diastolic dysfunction and degree of DD in patients who had normal ejection fraction who underwent outpatient echocardiography. They used echocardiography since it is one of the most common ...
https://www.indiaheartbeat.com/news-highlights/1.html?year=2011&month=06
Beneficial Effects of Angiotensin-(1-7) Against Deoxycorticosterone Acetate-Induced Diastolic Dysfunction Occur Independently...Beneficial Effects of Angiotensin-(1-7) Against Deoxycorticosterone Acetate-Induced Diastolic Dysfunction Occur Independently...
Here, we show that in vivo Ang-(1-7) protective signaling against DOCA-induced diastolic dysfunction occurs independently of its lowering BP effects and is mediated at the cardiomyocyte level by the activation of molecular pathways involved in Ca2+ handling, hypertrophy, and cell survival. By dissociating the BP effect of Ang-(1-7), we were capable of showing that BP attenuation in TG-DOCA represents a minor component of Ang-(1-7) beneficial effects. In addition, we show that Ang-(1-7) protective signaling occurs even under conditions of moderately high BP because TG-DOCA rats were hypertensive. Altogether, these findings provide the mechanistic input necessary to develop new strategies for clinical use of Ang-(1-7) alone or in combination with other drugs in patients with diastolic heart failure (HF).. Clinical studies have demonstrated the importance of MR antagonists for the prognostic improvement of patients with chronic HF.16,17 Preclinical data have shown strong evidence that Ang-(1-7) ...
http://hyper.ahajournals.org/content/66/2/389
Evaluation of LVDD by CCTA with Dual-source CT in Type 2 DiaEvaluation of LVDD by CCTA with Dual-source CT in Type 2 Dia
Background: Left ventricular diastolic dysfunction (LVDD) is a common abnormality among patients in T2DM. Aims: We aimed to evaluate the feasibility
http://www.currentmedicalimagingreviews.com/articles/176987/evaluation-of-lvdd-by-ccta-with-dual-source-ct-in-type-2-diabetes-mellitus-patients
US7527599B2 - Method of determining cardiac indicators - Google Patents
A system and method for determining indicators of left ventricular function, and for determining the effectiveness of a cardiac therapy are disclosed. The indicators of left ventricular function can include isovolumetric relaxation time and the negative slope of a V wave obtained from measuring changes in left atrial pressure during diastole. The apparatus may include a catheter comprising an inflatable balloon for insertion into the esophagus of an individual, a compressor device for pressurizing the balloon, and a means for sensing and recording pressure changes on the balloon.
https://patents.google.com/patent/US7527599B2/en
Systole & Diastole | Caracas Game Jam 2017Systole & Diastole | Caracas Game Jam 2017
Two players must pump a human heart by clicking two buttons in coordination: one acts as the systole movement, the other as the diastole. Pictures indicate what the character is doing, so the players must reproduce the heart rate according to the activity (e.g., running). The heart will receive damage (and eventually die) if the players press their buttons at the same time or if they play the wrong rhythm. When they keep pumping the heart to match the correct heartbeat for a short amount of time, they pass to a new activity. Aim for a high score! Tried in Chrome & Firefox. Best played with headphones ...
http://www.caracasgamejam.com/2013/systole-diastole
About the K.G. Jebsen Centre for Cardiac Research - Institute of Clinical Medicine
Traditionally, heart failure is associated with reduced pumping capacity of the heart. However, deteriorated filling of the heart, known as diastolic dysfunction, has recently been acknowledged as a prominent cause of HF, accounting for nearly 50% of all cases.. Diastolic dysfunction is linked to increased stiffness of the myocardium, and is highly relevant in patients with for instance aortic stenosis, hypertension, diabetes and cardiomyopathies.. There is currently no effective medical treatment for diastolic dysfunction. This suggests that important pathological mechanisms remain unknown. Our primary objective is therefore to identify the key mechanisms underlying diastolic dysfunction.. ...
https://www.med.uio.no/klinmed/english/research/centres/kgj-cardiac-research/about/index.html
Leaning About Diastolic Hypertension Issues
I clicked here to discover what in the heck diastolic hypertension is and how to treat it. Everyone knows about high blood pressure, and how it can cause a host
http://www.madisoncountyhealthdepartment.org/leaning-about-diastolic-hypertension-issues/1264/
Diastolic dysfunction brings on heart failure | Health24Diastolic dysfunction brings on heart failure | Health24
A common form of heart trouble called diastolic dysfunction appears to worsen over time and may lead to an increased risk of heart failure, new research shows.
https://www.health24.com/Medical/Heart/News/Diastolic-dysfunction-brings-on-heart-failure-20120721
Chest pain in a middle-aged maleChest pain in a middle-aged male
The acute ECG (first one at top) clearly shows the previous MI (Q-waves). The T-waves are upright. Is this pseudonormalization? No. Over weeks to months and certainly years, inverted T-waves of MI normalize as part of the natural history of the ECG in MI (Although, in LV aneurysm, they often remain with shallow invertion). So before this acute event the T-waves were likely upright ...
http://hqmeded-ecg.blogspot.com.au/2014/04/chest-pain.html
Cardiac Cycle - Systole & Diastole - Cardiology - Environment Manipur
now, today well be talking about the cardiac cycle. and the cardiac cycle well be discussing in two fashions, and one way we will discussing cardiac cycle while I will be doing different diagrams and in second phase, Well discuss the cardiac cycle Uhhhhh, When I will be presenting the errands during the cardiac cycle Graphically So first of all, ...
https://environmentmanipur.com/cardiac-cycle-systole-diastole-cardiology/
DiastoleDiastole
Atrial diastole is the relaxing of the atria, and ventricular diastole the relaxing of the ventricles. The term originates from ... Early diastole is a suction mechanism between the atrial and ventricular chambers. Then, in late ventricular diastole, the two ... Sabbah, H. N.; Stein, P. D. (1981). "Pressure-diameter relations during early diastole in dogs. The role of suction in Diastole ... Diastole (/daɪˈæstəli/ dy-AST-ə-lee) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling ...
https://en.wikipedia.org/wiki/Diastole
Diastole (gastropod)Diastole (gastropod)
Species in the genus Diastole include: [1] Diastole bryani H. B. Baker, 1938 Diastole conula (Pease, 1861) Diastole exposita ( ... Diastole futunae H. B. Baker, 1938 Diastole glaucina Baker, 1938 Diastole lamellaxis Baker, 1938 Diastole lauae H. B. Baker, ... 1938 Diastole rurutui H. B. Baker, 1938 Diastole savaii Baker, 1938 Diastole schmeltziana (Mousson, 1865) Diastole simonei ... Thach & F. Huber, 2017 (taxon inquirendum) Diastole subcarinata Solem, 1959 Diastole tenuistriata Preece, 1995 Diastole tongana ...
https://en.wikipedia.org/wiki/Diastole_(gastropod)
Diastole tenuistriataDiastole tenuistriata
... is a species of air-breathing land snails or semi-slugs, terrestrial pulmonate gastropod mollusks in the ... Preece, R.C. (1996). "Diastole tenuistriata". IUCN Red List of Threatened Species. 1996: e.T6524A12787385. doi:10.2305/IUCN.UK. ... Diastole (gastropod), Fauna of the Pitcairn Islands, Molluscs of Oceania, Vulnerable fauna of Oceania, Gastropods described in ...
https://en.wikipedia.org/wiki/Diastole_tenuistriata
Hawking (band)Hawking (band)
Diastole 05. Systole [1] Ghettoblaster Magazine, June 24, 2015. [2] MusicBox Pete June 29, 2015 "Hawking Introduces Us To Math ...
https://en.wikipedia.org/wiki/Hawking_(band)
List of Oceanian animals extinct in the HoloceneList of Oceanian animals extinct in the Holocene
Mollusc Specialist Group (1996). "Diastole matafaoi". IUCN Red List of Threatened Species. 1996: e.T6523A12787323. doi:10.2305/ ...
https://en.wikipedia.org/wiki/List_of_Oceanian_animals_extinct_in_the_Holocene
Mount Matafao different snailMount Matafao different snail
The Mount Matafao different snail, scientific name Diastole matafaoi, was a species of air-breathing land snails or semi-slugs ... Mollusc Specialist Group (1996). "Diastole matafaoi". IUCN Red List of Threatened Species. 1996: e.T6523A12787323. doi:10.2305/ ... Diastole (gastropod), Extinct gastropods, Extinct animals of Oceania, Fauna of American Samoa, Molluscs of Oceania, Extinct ...
https://en.wikipedia.org/wiki/Mount_Matafao_different_snail
Ragavendra R. BaligaRagavendra R. Baliga
Energizing diastole. Heart Fail Clin. 2008 Jan;4(1):ix-xiii. Review. PMID 18313619. Baliga RR, Young JB. Never too late to ...
https://en.wikipedia.org/wiki/Ragavendra_R._Baliga
Alfons SiewertAlfons Siewert
Siewert, A. K. (December 1922). "Über aktive Diastole" [About active diastole]. Zeitschrift für die Gesamte Experimentelle ... He also conducted studies on the biochemical changes in urine as a result of eating meat in 1912, and on diastole in 1922 ...
https://en.wikipedia.org/wiki/Alfons_Siewert
Diastolic functionDiastolic function
During diastole, the ventricle of heart must remain elastic or compliant enough and have capacity to hold incoming blood to ... Brutsaert, D. L.; Sys, S. U. (1989-10-01). "Relaxation and diastole of the heart". Physiological Reviews. 69 (4): 1228-1315. ...
https://en.wikipedia.org/wiki/Diastolic_function
SystoleSystole
In late ventricular diastole, the atrial chambers contract and send blood to the larger, lower ventricle chambers. This flow ... Both valves are pressed open during the late stages of ventricular diastole; see Wiggers diagram at the P/QRS phase (at right ... Atrial systole lasts approximately 100 ms and ends prior to ventricular systole, as the atrial muscle returns to diastole. The ... Atrial systole occurs late in ventricular diastole and represents the contraction of myocardium of the left and right atria. ...
https://en.wikipedia.org/wiki/Systole
HypodiastoleHypodiastole
"diastole, n." Oxford University Press (Oxford), 1895. Nicolas, Nick. "Greek Unicode Issues: Punctuation Archived November 20, ... lower separation [mark]'), also known as a diastole, was an interpunct developed in late Ancient and Byzantine Greek texts ...
https://en.wikipedia.org/wiki/Hypodiastole
Wiggers diagramWiggers diagram
Ventricular systole Cardiac diastole ECG The EKG complex. P=P wave, PR=PR interval, QRS=QRS complex, QT=QT interval, ST=ST ...
https://en.wikipedia.org/wiki/Wiggers_diagram
Heart murmurHeart murmur
These differ in the part of the heartbeat they make sound, during systole, or diastole. Yet, continuous murmurs create sound ... This causes collision with the mitral inflow during diastole. As such, the mitral valve orifice narrows. This results in ...
https://en.wikipedia.org/wiki/Heart_murmur
Ventricle (heart)Ventricle (heart)
During diastole, the ventricles relax and fill with blood again. The left ventricle receives oxygenated blood from the left ...
https://en.wikipedia.org/wiki/Ventricle_(heart)
Mitral valveMitral valve
During left ventricular diastole, after the pressure drops in the left ventricle due to relaxation of the ventricular ... In normal conditions, blood flows through an open mitral valve during diastole with contraction of the left atrium, and the ... Left atrial contraction (left atrial systole) (during left ventricular diastole) causes added blood to flow across the mitral ... Type IIIa pertains to restrictive motion during systole and diastole. Type IIIb pertains to restrictive motion during systole. ...
https://en.wikipedia.org/wiki/Mitral_valve
Mitral stenosisMitral stenosis
... diastole, and the pressures in the left atrium and the left ventricle during ventricular diastole will be equal. The result is ... As the heart rate increases, the amount of time that the ventricle is in diastole and can fill up with blood (called the ... Normally, the mitral valve is about 5 cm2 during diastole. Any decrease in area below 2 cm2 causes mitral stenosis. Early ... In normal cardiac physiology, the mitral valve opens during left ventricular diastole, to allow blood to flow from the left ...
https://en.wikipedia.org/wiki/Mitral_stenosis
Functional murmurFunctional murmur
Occurs during systole or continuously during both systole and diastole. (Murmurs occurring only during diastole are usually ...
https://en.wikipedia.org/wiki/Functional_murmur
Edgar SnowEdgar Snow
Diastole Hospital Hill, Inc., University of Missouri-Kansas City, 1985. Farnsworth, Robert. Edgar Snow's Journey South of the ...
https://en.wikipedia.org/wiki/Edgar_Snow
Amyloid cardiomyopathyAmyloid cardiomyopathy
This limits ventricular filling during diastole, which increases end-diastolic volume. This can lead to a variety of cardiac ...
https://en.wikipedia.org/wiki/Amyloid_cardiomyopathy
Cardiac cycleCardiac cycle
Atrial systole overlaps the end of the diastole, occurring in the sub-period known as ventricular diastole-late (see cycle ... Starting with the Diastole period: the low-volume plateau of "Isovolumic relaxation" stage, followed by a rapid rise and two ... This period is best viewed at the middle of the Wiggers diagram-see the panel labeled "Diastole". Here it shows pressure levels ... It consists of two periods: one during which the heart muscle relaxes and refills with blood, called diastole, following a ...
https://en.wikipedia.org/wiki/Cardiac_cycle
Admittance and conductance in cardiac performanceAdmittance and conductance in cardiac performance
"Volume catheter parallel conductance varies between end-systole and end-diastole". IEEE Trans Biomed Eng. 54 (8): 1480-9. doi: ...
https://en.wikipedia.org/wiki/Admittance_and_conductance_in_cardiac_performance
HemodynamicsHemodynamics
P I = v s y s t o l e − v d i a s t o l e v m e a n {\displaystyle PI={\frac {v_{systole}-v_{diastole}}{v_{mean}}}} Resistance ... What is left at the end of diastole (EDV) minus the stroke volume make up the end diastolic volume (ESV). Circulatory system of ... Blood velocities in arteries are higher during systole than during diastole. One parameter to quantify this difference is the ...
https://en.wikipedia.org/wiki/Hemodynamics
Heart failure with preserved ejection fractionHeart failure with preserved ejection fraction
During diastole, the ventricular pressure falls from the peak reached at the end of systole. When this pressure falls below the ... Diastole has four phases: isovolumetric relaxation, rapid filling, diastasis and atrial contraction. All of these phases can be ... In diastolic heart failure, the volume of blood contained in the ventricles during diastole is lower than it should be, and the ... Mathematics describing the relationship between the ratio of Systole to Diastole in accepted terms of End Systolic Volume to ...
https://en.wikipedia.org/wiki/Heart_failure_with_preserved_ejection_fraction
Bowditch effectBowditch effect
As the heart rate becomes more robust, and the length of diastole decreases, the Na+/K+-ATPase, which removes the Na+ brought ... This occurs because of the decreased length of diastole with positive chronotropy. With an increased intracellular Ca++ ...
https://en.wikipedia.org/wiki/Bowditch_effect
Contractile vacuoleContractile vacuole
The stage in which water flows into the CV is called diastole. The contraction of the contractile vacuole and the expulsion of ...
https://en.wikipedia.org/wiki/Contractile_vacuole
Pulsus bisferiensPulsus bisferiens
In severe aortic regurgitation, additional blood reenters the left ventricle during diastole. This added volume of blood must ...
https://en.wikipedia.org/wiki/Pulsus_bisferiens
Aortic valve replacementAortic valve replacement
During cardiac diastole (when the heart chamber gets bigger) the aortic valve closes. Aortic stenosis most commonly is the ... connective tissue disorders such as Marfan syndrome or Ehlers-Danlos lead to imperfect closure of the valve during diastole, ...
https://en.wikipedia.org/wiki/Aortic_valve_replacement
Windkessel effectWindkessel effect
... where td is the time of the start of diastole and P(td) is the blood pressure at the start of diastole. This model is only a ... During diastole there is no blood inflow since the aortic (or pulmonary valve) is closed, so the Windkessel can be solved for P ... An example for the two-element model is shown below, where I(t) is depicted as an input signal during systole and diastole. ... Systole is represented by the sin function, while flow during diastole is zero. s represents the duration of the cardiac cycle ...
https://en.wikipedia.org/wiki/Windkessel_effect
Trypanosoma cruziTrypanosoma cruzi
This change in repolarization inhibits the heart from relaxing and properly entering diastole. Changes in the ventricular ...
https://en.wikipedia.org/wiki/Trypanosoma_cruzi
History of continuous noninvasive arterial pressureHistory of continuous noninvasive arterial pressure
On the other hand, during diastole, the blood volume in the finger is decreased; as a result the PID-controller decreases the ...
https://en.wikipedia.org/wiki/History_of_continuous_noninvasive_arterial_pressure
Diastole (vanha projekti) - Out of night lifeDiastole (vanha projekti) - Out of night life
... MP3 Heavy Metal ... Diastole (vanha projekti). www.mikseri.net/artists/ ...
https://www.mikseri.net/artists/diastole-vanha-projekti/out-of-night-life/252799/?displ_lang=en
DIASTOLE | Meaning & Definition for UK English | Lexico.comDIASTOLE | Meaning & Definition for UK English | Lexico.com
UK English definition of DIASTOLE along with additional meanings, example sentences, and ways to say. ... It relaxes slowly in early diastole and offers greater resistance to filling in late diastole, so that diastolic pressures are ... Coronary blood flow occurs during diastole, and as the heart rate increases diastole shortens. ... Systole is that part of the hearts pumping cycle when it contracts and pushes blood out, the pulse if you like, and diastole ...
https://www.lexico.com/definition/diastole
LOINC 18153-7 - Right ventricular anterior wall Thickness during diastole by USLOINC 18153-7 - Right ventricular anterior wall Thickness during diastole by US
LOINC Code 18153-7 Right ventricular anterior wall Thickness during diastole by US ... Thickness.diastole. Property. Len. Time. Pt. System. Heart.ventricle.right.anterior wall. Scale. Qn. Method. US. Additional ... Spessore.diastole:. Len:. Pt:. Cuore.ventricolo.destro.parete anteriore:. Qn:. Ecografia. pt-BRPortuguese (Brazil). Espessura. ... 18153-7Right ventricular anterior wall Thickness during diastole by USActive. Fully-Specified Name. Component. ...
https://loinc.org/loinc/18153-7/
The Echocardiographer and Diastole<...
The Echocardiographer and Diastole. / DAVIDSON, WILLIAM R.. In: Echocardiography, Vol. 9, No. 3, 05.1992, p. 287.. Research ... DAVIDSON, WILLIAM R. / The Echocardiographer and Diastole. In: Echocardiography. 1992 ; Vol. 9, No. 3. pp. 287. ... The Echocardiographer and Diastole. Echocardiography. 1992 May;9(3):287. https://doi.org/10.1111/j.1540-8175.1992.tb00471.x ... R. (1992). The Echocardiographer and Diastole. Echocardiography, 9(3), 287. https://doi.org/10.1111/j.1540-8175.1992.tb00471.x ...
https://pennstate.pure.elsevier.com/en/publications/the-echocardiographer-and-diastole
Resultat #1882112 - Estimation of End-Diastole in Cardiac Spectral Doppler Using Deep Learning - Cristin Resultat #1882112 - Estimation of End-Diastole in Cardiac Spectral Doppler Using Deep Learning - Cristin
Estimation of End-Diastole in Cardiac Spectral Doppler Using Deep Learning ...
https://app.cristin.no/results/show.jsf?id=1882112
DIASTOLE EVENTS | diastoleDIASTOLE EVENTS | diastole
Diastole Scholars Center is covered by the new UMKC policy on a smoke- and tobacco-free campus.. ...
https://www.diastole.org/diastole-events
Diastole
... So like I spend half my time doing strenuous physical activity, and the other half lying on the chaise covered in ...
http://www.allapoppy.com/2010/01/diastole.html
Cardiac Auscultation in the Older AdultCardiac Auscultation in the Older Adult
Listen to Late Diastole. An extra sound in late diastole suggests an S4 gallop (usually right ventricular). ... Listen to Early Diastole. Hearing an extra sound suggests an S3 gallop (usually right ventricular), an opening snap, the ...
https://www.medscape.com/viewarticle/756829_3
Favorable effects of non-instrumental resistance training on fat distribution and metabolic profiles in healthy elderly peopleFavorable effects of non-instrumental resistance training on fat distribution and metabolic profiles in healthy elderly people
This study examined the effect of a 12-week non-instrumental resistance training program using body weight as a load (RT-BW) on body composition, fat distribution and metabolic profiles in elderly males and females. Healthy, non-diabetic, elderly volunteers (22 males and 30 females) aged 65-82 years …
https://pubmed.ncbi.nlm.nih.gov/17219171/?dopt=Abstract
Optison (Perflutren Protein-Type A Microspheres): Uses, Dosage, Side Effects, Interactions, WarningOptison (Perflutren Protein-Type A Microspheres): Uses, Dosage, Side Effects, Interactions, Warning
Intensity at End-Diastole. Intensity at End-Systole. Intensity at End-Diastole. Intensity at End-Systole. ... Optison significantly increased the length of endocardial border that could be visualized both at end-systole and end-diastole ...
https://www.rxlist.com/optison-drug.htm
Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal SystemExercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System
Ventricular diastole. *. This phase begins with the opening of the atrioventricular (AV) valves. The mitral valve (located ... At the end of the diastole, left atrial contractions cause an increase in left atrial pressure, thus again creating a pressure ... The cardiac cycle is divided into 2 phases: ventricular diastole and ventricular systole. ...
http://emedicine.medscape.com/article/88484-overview
Systole - WikipediaSystole - Wikipedia
Atrial systole occurs late in ventricular diastole and represents the contraction of myocardium of the left and right atria. ... Atrial systole lasts approximately 100 ms and ends prior to ventricular systole, as the atrial muscle returns to diastole.[4] ... Both valves are pressed open during the late stages of ventricular diastole; see Wiggers diagram at the P/QRS phase (at right ... When, in late ventricular diastole, the atrial chambers contract, they send blood down to the larger, lower ventricle chambers ...
https://en.wikipedia.org/wiki/Systole_
Article | PfizerArticle | Pfizer
If you have atopic dermatitis-the most common type of eczema-you may be all too familiar with the periodic flare-ups and the itching that often is worse at night and can interfere with sleep. Along with atopic dermatitis, you may have other co-occurring conditions such as food allergies or asthma. You may also have an increased risk for co-existing conditions such as skin infections, heart disease, cancer, depression or anxiety. These issues can have both an emotional and social impact on your life. ...
https://www.pfizer.com/news/articles?featured_stories_keywords_filter=17166
Mouse Echocardiography | FUJIFILM VisualSonicsMouse Echocardiography | FUJIFILM VisualSonics
Learn how you can perform reliable echocardiograms for translational cardiovascular research in small animals, in vivo with resolution down to 30 microns.
https://www.visualsonics.com/application/preclinical/cardiology?field_application_tid=2&date=2021-11
Fairness in Cardiac Magnetic Resonance Imaging: Assessing Sex and Racial Bias in Deep Learning-based Segmentation | medRxivFairness in Cardiac Magnetic Resonance Imaging: Assessing Sex and Racial Bias in Deep Learning-based Segmentation | medRxiv
End diastole. EF. Ejection fraction. ES. End systole. LV. Left ventricle. References. *1.↵. Constantinides, Panos Fitzmaurice ... The dataset consisted of end-diastole and end-systole short-axis cine CMR images of 5,903 subjects from the UK Biobank database ... from cine short-axis CMR slices at end-diastole (ED) and end-systole (ES). This model was chosen as it has performed well ...
https://www.medrxiv.org/content/10.1101/2021.07.19.21260749v2.full
Hemodynamic force assessment by cardiovascular magnetic resonance in HFpEF: A case-control substudy from the HFpEF stress trial...Hemodynamic force assessment by cardiovascular magnetic resonance in HFpEF: A case-control substudy from the HFpEF stress trial...
Top: Traced left ventricular contours in 2/3/4 chamber view (CV) orientations in end-diastole and -systole in a patient with ... Top: Traced left ventricular contours in 2/3/4 chamber view (CV) orientations in end-diastole and -systole in a patient with ... LV contours were manually traced at end-systole (ES) and end-diastole (ED). The tracking algorithm was then applied to ... this research addresses specific phases within systole and diastole. This may explain why subtle differences were detected ...
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964
CIRCULATORY Flashcards by Sydnee Sparks | BrainscapeCIRCULATORY Flashcards by Sydnee Sparks | Brainscape
diastole period when specific chambers of the heart relax after a contraction ...
https://www.brainscape.com/flashcards/circulatory-6587937/packs/10438994
0-1 Chapter 19 the heart Flashcards by Dennis Dickenson | Brainscape0-1 Chapter 19 the heart Flashcards by Dennis Dickenson | Brainscape
during diastole, ventricles expand. -their pressure drops below that of the atria. -AV valves open and blood flows into the ... during ventricular diastole, blood in the aorta surges back toward the heart and into the openings of the coronary arteries. • ... diastole becomes too brief for adequate filling. -both stroke volume and cardiac output are reduced ... early ventricular diastole. -when T wave ends and the ventricles begin to expand ...
https://www.brainscape.com/flashcards/0-1-chapter-19-the-heart-1325851/packs/2441214
Table 2 - Trypanosoma cruzi in Persons without Serologic Evidence of Disease, Argentina - Volume 9, Number 12-December 2003 -...
... left ventricular diameter in diastole; LVEF, left ventricular ejection fraction; ND, not determinate. ...
https://wwwnc.cdc.gov/eid/content/9/12/1558-t2.htm
These highlights do not include all the information needed to use DEFINITY safely and effectively. See full prescribing...These highlights do not include all the information needed to use DEFINITY safely and effectively. See full prescribing...
Table 3 MEAN (SD) ENDOCARDIAL BORDER LENGTH (CM) BY BOTH APICAL 2- AND 4-CHAMBER VIEWS AT END-SYSTOLE AND END-DIASTOLE BY STUDY ... The mean change in border length from baseline at end-diastole was statistically significant for all readers in the apical 4- ... kg of activated DEFINITY increased the length of endocardial border that could be measured at both end-systole and end-diastole ... measured by videodensitometry at end-diastole and end-systole). ... Mean(SD) at End-Diastole. Mean(SD) at End-Systole. Reader 1. ...
https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=8ab9c79c-1b5c-4e86-899c-cc74686f070a&type=display
DailyMed - DEFINITY RT- perflutren injection, suspensionDailyMed - DEFINITY RT- perflutren injection, suspension
Table 3 MEAN (SD) ENDOCARDIAL BORDER LENGTH (CM) BY BOTH APICAL 2- AND 4-CHAMBER VIEWS AT END-SYSTOLE AND END-DIASTOLE BY STUDY ... The mean change in border length from baseline at end-diastole was statistically significant for all readers in the apical 4- ... kg of activated DEFINITY increased the length of endocardial border that could be measured at both end-systole and end-diastole ... measured by videodensitometry at end-diastole and end-systole). ... Mean(SD) at End-Diastole. Mean(SD) at End-Systole. Reader 1. ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7b9de6ab-a3ac-40c9-8103-139dc7a464a2
Simulation of the Frank-Starling Law of the HeartSimulation of the Frank-Starling Law of the Heart
It has two peaks: a large early mitral flow in early diastole and a small late mitral flow in late diastole. The latter ... Note the "hump" in AtP in late diastole. Note also that the early mitral flow commences when AtP = VP. The higher is this ... If atrium is not contracting, there is no "hump" in AtP in late diastole. However, also in this condition the early mitral flow ... The time course of cardiovascular variables during a single systole and diastole is presented in Figure 5, in columns A, B, and ...
https://www.hindawi.com/journals/cmmm/2012/267834/
Blood Pressure, Left Ventricular Geometry, and Systolic Function in Children Exposed to Inorganic Arsenic | Environmental...Blood Pressure, Left Ventricular Geometry, and Systolic Function in Children Exposed to Inorganic Arsenic | Environmental...
... posterior wall thickness in diastole (PWTD), and interventricular septum thickness in diastole (IVSTD). Left ventricular mass ( ... Measurements were obtained for aortic root diameter (ARD), left atrial diameter (LAD), LV internal diameter in diastole (LVIDD ... Abbreviations: ARD, aortic root diameter; GM, geometric mean; IVSTD, interventricular septum thickness in diastole; LAD, left ... posterior wall thickness in diastole; RWT, relative wall thickness. a. According to Daniels et al. (1995) and Hirth et al. ( ...
https://ehp.niehs.nih.gov/doi/10.1289/ehp.1307327
Johannes Jan Struijk - Publications - Aalborg Universitys Research PortalJohannes Jan Struijk - Publications - Aalborg University's Research Portal
Nielsen, J. B., Kühl, J. T., Pietersen, A., Graff, C., Lind, B., Struijk, J., Olesen, M. S., Sinner, M. F., Bachmann, T. N., Haunsø, S., Nordestgaard, B. G., Ellinor, P. T., Svendsen, J. H., Kofoed, K. F., Køber, L. & Holst, A. G., 2015, In: Heart Rhythm. 12, 9, p. 1887-1895. Research output: Contribution to journal › Journal article › Research › peer-review ...
https://vbn.aau.dk/en/persons/102981/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle
Publications | Ahmed M. Gharib, M.D. | NIDDKPublications | Ahmed M. Gharib, M.D. | NIDDK
Coronary MR angiography at 3T during diastole and systole.. Gharib AM, Herzka DA, Ustun AO, Desai MY, Locklin J, Pettigrew RI, ...
https://www.niddk.nih.gov/about-niddk/staff-directory/biography/gharib-ahmed/publications
Expert Review of the Vieques Heart Study Summary Report for the Vieques Heart Study Expert Panel Review | Vieques, Puerto Rico ...Expert Review of the Vieques Heart Study Summary Report for the Vieques Heart Study Expert Panel Review | Vieques, Puerto Rico ...
d. LV septal thickness (end-diastole; standard way). e. LV septal thickness (end-systole). f. LV posterior wall (end-diastole; ... l. Mitral valve DE amplitude (early diastole). m. Pericardial thickness (end-diastole) from standard, non-magnified - Mode ... A study of 18 healthy subjects using MR imaging found the average pericardial thickness to be 1.2 mm (± 0.5 mm) in diastole and ... h. LV internal dimension (end-diastole). i. LV internal dimension (end-systole). j. Mitral valve E-point-septal-separation. k. ...
http://www.atsdr.cdc.gov/sites/vieques/heart_study_summary.html
Heart and Circulatory System (for Teens) - Ann & Robert H. Lurie Childrens Hospital of Chicago (XML)Heart and Circulatory System (for Teens) - Ann & Robert H. Lurie Children's Hospital of Chicago (XML)
The second phase is called diastole (pronounced: die-AS-tuh-lee). This is when the atrioventricular valves open and the ...
https://www.kidshealth.org/LurieChildrens/en/teens/heart.html
Bicuspid Aortic Valve: Background, Pathophysiology, EpidemiologyBicuspid Aortic Valve: Background, Pathophysiology, Epidemiology
In diastole, hammocking (prolapse) of the valve cusps occurs. The short-axis view shows the irregular sclerotic margins. This ... Two-dimensional echocardiogram of typical bicuspid aortic valve in diastole and systole. Valve margins are thin and pliable and ... Parasternal short-axis echocardiographic view in diastole, showing bicuspid aortic valve with nearly equal cusp size and right- ...
https://emedicine.medscape.com/article/893523-overview
Glucagon-Like Peptide-1 Analog Liraglutide Protects against Diabetic Cardiomyopathy by the Inhibition of the Endoplasmic...Glucagon-Like Peptide-1 Analog Liraglutide Protects against Diabetic Cardiomyopathy by the Inhibition of the Endoplasmic...
... peak early transmitral filling velocity during early diastole; A: peak transmitral atrial filling velocity during late diastole ...
https://www.hindawi.com/journals/jdr/2013/630537/
Apis Mellifica chest symptoms by Hering - ABC HomeopathyApis Mellifica chest symptoms by Hering - ABC Homeopathy
Blowing sound with the diastole.. Pulse accelerated, full and strong; feeble, scarcely perceptible at wrist; at times ...
https://abchomeopathy.com/r.php/Apis/chest/Hering
Systole and diasAtrial diastolePhase of the cardiac cycleCardiacRelaxationVentriclesPhasesAortaContractionRepresentation of bloodHeartbeatHeartAorticLeftBlood PressureTimeLongerEarly diastoleEchocardiographyVenous flowOccursThicknessPulmonaryCoronary arteriesRelaxesAtrial systoleVentricular systoleRelaxation phaseSeptalPulseVelocityCephaladVentricleDiastolic pressureBeatsFlowPressurePeriodTimePumpLateSoundPhaseWallShort
Systole and dias4
  • Since blood flow through the heart is continuous rather than periodic, the terms 'systole' and 'diastole' are used to describe the periods when blood enters and leaves the heart, respectively. (staminacomfort.com)
  • Diagram showing the phases of the cardiac cycle: systole and diastole. (staminacomfort.com)
  • In M mode were obtained, at the end of systole and diastole, the internal dimension of the left ventricle, the thickness of the interventricular septum and posterior wall of the left ventricle, according to Lombard (1984). (vin.com)
  • Ventricular Pumping during Systole and Diastole. (thegatheringbaltimore.com)
Atrial diastole1
Phase of the cardiac cycle2
  • Diastole is the phase of the cardiac cycle when the heart relaxes following contraction or systole. (news-medical.net)
  • Systole is the contraction phase of the cardiac cycle, and diastole is the relaxation phase. (thegatheringbaltimore.com)
Cardiac6
  • The cardiac cycle consists of three parts: diastole, systole, and diastasis. (staminacomfort.com)
  • The cardiac cycle is divided into two phases: diastole and systole. (staminacomfort.com)
  • The order is: atrial systole → ventricular systole → cardiac diastole. (wikipedia.org)
  • This increase in preload occurs simultaneously with diastole which happens to be the time during the cardiac cycle in which coronary perfusion occurs. (wikipedia.org)
  • The cardiac cycle refers to all of the events that occur from the beginning of one heartbeat to the beginning of the next and can be divided into two parts: a period of relaxation known as diastole and a period of contraction known as systole. (thegatheringbaltimore.com)
  • It can be calculated by multiplying the total peripheral resistance by the cardiac output and it can vary from a maximum value during systoles and a minimum value during diastoles 23 . (bvsalud.org)
Relaxation3
  • Diastole is the time of heart ventricular relaxation after blood is ejected into the aorta and pulmonary trunk. (staminacomfort.com)
  • Systole is the contraction of the heart to pump blood out, while diastole is the relaxation of the heart following contraction. (staminacomfort.com)
  • During the Mid-to-Late Diastole, the heart is in complete relaxation, and the pressure in the heart is low. (proprofs.com)
Ventricles5
  • Diastole is the period between heartbeats when the ventricles are relaxed. (staminacomfort.com)
  • At the end of diastole, the muscles of the heart tighten up again, causing the ventricles to squeeze during systole. (staminacomfort.com)
  • During diastole, the ventricles are relaxed so that blood can flow back into them. (staminacomfort.com)
  • The ventricles begin to fill during ventricular diastole. (proprofs.com)
  • Diastole is when the ventricles relax and fill with blood pumped into them by the atria. (heartandstrokehealth.com)
Phases1
Aorta3
  • During diastole, the walls of the left ventricle relax and allow blood to return to the heart from the aorta and pulmonary trunk. (staminacomfort.com)
  • Imaging of endovascular flow patterns in the abdominal aorta is challenging, due to the anatomical position of these arteries and flow velocities ranging between 1 m/s and backward flow during diastole. (utwente.nl)
  • reduced and reversed flow during diastole in the descending aorta in combination with clinical signs. (hindawi.com)
Contraction2
  • Diastole also includes the time before the next contraction (systole) begins. (staminacomfort.com)
  • Diastole begins when the atria begin to relax after contraction. (staminacomfort.com)
Representation of blood1
  • Left, streamline representation of blood flow velocities during early diastole in volunteer 7. (utwente.nl)
Heartbeat2
  • The period from initiation of systole to completion of diastole is called one heartbeat. (staminacomfort.com)
  • Then the heart muscle relaxes (called diastole ) before the next heartbeat. (howstuffworks.com)
Heart6
  • Diastole is more complexly related to heart rate and lasts longer at low heart rates . (staminacomfort.com)
  • The cycle of the heart starts with diastole. (staminacomfort.com)
  • Describe the Lub Dub of the heart: Systole vs Diastole. (booksbydan.com)
  • When the heart muscle relaxes (stops pushing in), this is called diastole . (wikipedia.org)
  • Systole is when the heart is squeezing out blood and diastole is when it is filling up with blood. (medlineplus.gov)
  • Diastolic dysfunction is a heart condition that affects the organ's capacity to fill with an adequate amount of blood during diastole. (news-medical.net)
Aortic1
  • The second sound -- the "DUB" -- is made by the aortic and pulmonary valves closing at the beginning of diastole (di-AS-toe-lee). (heartandstrokehealth.com)
Left2
  • The peak pressure is called systole , and the pressure that is maintained even while the left ventricle is relaxing is called diastole . (vernier.com)
  • Left ventricular cavity size was determined at end-diastole and end-systole. (bmj.com)
Blood Pressure14
  • Can I Take Benadryl With High Blood Pressure diastole and systole blood pressure SC-Freising Volleyball food to avoid when you have high blood pressure Flomax And Blood Pressure. (volleyball-freising.de)
  • Tomorrow s headlines will be O Neal is blood pressure medication safe during pregnancy not optimistic about diastole and systole blood pressure this year s rookie Li Yi , but after Barkley s remarks, the headlines food to avoid when you have high blood pressure Viagra And High Blood Pressure will become Barkley thinks Lee He is an all time shooter, even comparable to Ray Allen. (volleyball-freising.de)
  • Naturally, Ellis would not say that Li diastole and systole blood pressure Yi in front of him reminded himself of the backcourt player they chose when he was in the Warriors, even though he told the management that he did not want the team to choose a point guard. (volleyball-freising.de)
  • Don t talk diastole and systole blood pressure Will Benadryl Lower Blood Pressure about it later Korver thought about it and said to Li Yi, If you want to talk about it, go back and talk to your agent. (volleyball-freising.de)
  • He diastole and systole blood pressure Will Benadryl Lower Blood Pressure used Korver and Antic for Teague and Plumlee. (volleyball-freising.de)
  • God, is this social death You struck me with thunder Guo Yun s SC-Freising Volleyball diastole and systole blood pressure face turned red. (volleyball-freising.de)
  • Seeing diastole and systole blood pressure that there was no chance, Li Yi what bread is good for high blood pressure stopped outside the three point diastole and systole blood pressure line. (volleyball-freising.de)
  • diastole and systole blood pressure Lou Wei nodded slowly, he A decision has been Diavan Blood Pressure diastole and systole blood pressure made. (volleyball-freising.de)
  • Budenholzer turned his head to Li Yi and said Continue diastole and systole blood pressure to defend Wall, the Wizards want to let Bill play with the ball, then let him play. (volleyball-freising.de)
  • This match against the Heat will be their last match diastole and systole blood pressure diastole and systole blood pressure in the regular season. (volleyball-freising.de)
  • James hit the basket after the pick and roll, Bosh opened space for James, blood pressure equipments this is the Heat s offensive diastole and systole blood pressure tactics. (volleyball-freising.de)
  • With diastole and systole blood pressure the Pacers taking a strong lead and the Bulls chasing after them, the Eagles will be able to diastole and systole blood pressure maintain the No. (volleyball-freising.de)
  • He stepped past Teague again, and in diastole and systole blood pressure front diastole and systole blood pressure of him made diastole and systole blood pressure a pull diastole and systole blood pressure up jumper. (volleyball-freising.de)
  • Yes, without the most athletic person Blood Pressure Medicine Lisinopril food to avoid when you have high blood pressure on the Can You Take Benadryl With High Blood Pressure diastole and systole blood pressure inside, diastole and systole blood pressure Will Benadryl Lower Blood Pressure there is no way to give it a shot. (volleyball-freising.de)
Time1
  • Even though the atrial systole comes before ventricular systole , all four chambers do diastole at the same time. (wikipedia.org)
Longer1
Early diastole3
  • It relaxes slowly in early diastole and offers greater resistance to filling in late diastole, so that diastolic pressures are elevated. (lexico.com)
  • Several studies have suggested that the mitral annulus displacement and velocity in early diastole can be used as indicators of diastolic performance. (caltech.edu)
  • The peak velocity of the mitral annulus away from the LV apex during early diastole, which indicates the rate of longitudinal expansion of the LV, is reduced in patients with impaired diastolic relaxation. (caltech.edu)
Echocardiography2
  • Transthoracic echocardiography revealed normal left ventricular internal dimensions (5.4 cm diastole, 3.2 cm systole), normal septal and posterior wall thickness (0.9 cm and 1 cm respectively), an ejection fraction estimated at 70%, a normal diastolic ventricular filling pattern (E/A ratio 1.25), and normal valvular function. (bmj.com)
  • Echocardiography revealed left ventricular volume at diastole was increased and left ventricular mass decreased following high irradiation exposures. (nih.gov)
Venous flow1
  • We show that in the case of atrial fibrillation, the reversal pulmonary venous flow at late diastole disappear and also the filling waves at left atrial appendage orifice during systole have reduced magnitude. (gla.ac.uk)
Occurs5
  • Coronary blood flow occurs during diastole, and as the heart rate increases diastole shortens. (lexico.com)
  • The sharp decrease in ventricular pressure that occurs during ventricular diastole allows the atrioventricular valves (or mitral and tricuspid valves) to open and causes the contents of the atria to empty into the ventricles. (wikipedia.org)
  • Cuffs placed on the calves, lower thighs, and upper thighs are inflated sequentially during diastole when coronary artery filling occurs. (thefreedictionary.com)
  • Usually occurs at diastole. (nih.gov)
  • Which event occurs first during diastole? (easynotecards.com)
Thickness1
  • Err values drop to near zero indicated by green, indicating that elastic strains return to B) LV lateral wal thickness at end- diastole. (nih.gov)
Pulmonary4
  • 2) oxygen-depleted blood (blue arrow) in the right ventricle begins pulsing through the pulmonic (pulmonary) valve en route to the lungs for reoxygenation. (wikipedia.org)
  • The atrioventricular valves remain open while the aortic and pulmonary valves remain closed because the pressure gradient between the atrium and ventricle is preserved during late ventricular diastole. (wikipedia.org)
  • The product PVR×C characterises the decay of pulmonary arterial pressure in diastole and represents the time-constant of the pulmonary circulation (RC-time, with units of seconds). (ersjournals.com)
  • In the second phase, a slightly longer period of ventricular relaxation known as the diastole, the pulmonary and aortic valves close up, producing the characteristic "dub" sound. (thefreedictionary.com)
Coronary arteries1
  • Searching for methods for increasing the blood flow to hearts weakened by coronary artery blockage or other conditions, he discovered that it was possible to manipulate blood flow in the aorta so as to pulse it into the coronary arteries during diastole (the relaxation phase between heartbeats). (nih.gov)
Relaxes4
  • Systole is that part of the heart's pumping cycle when it contracts and pushes blood out, the pulse if you like, and diastole is when the heart relaxes and fills with blood ready for the next heartbeat. (lexico.com)
  • Blood pressure is measured both as the heart contracts, which is called systole, and as it relaxes, which is called diastole. (nih.gov)
  • When the heart relaxes (diastole), the ventricles fill with blood. (medmovie.com)
  • The second number is called diastole and it's the pressure when the heart relaxes and refills with blood. (epworth.org.au)
Atrial systole2
  • At the start of atrial systole, during ventricular diastole, the ventricles are normally filled to about 70 - 80 percent of capacity by inflow from the atria. (wikipedia.org)
  • Atrial systole lasts approximately 100 ms and ends prior to ventricular systole, as the atrial muscle returns to diastole. (wikipedia.org)
Ventricular systole2
  • These four anatomic components function to allow unobstructed blood flow from the left atrium to the LV during diastole and to maintain competent closure during ventricular systole. (medscape.com)
  • During ventricular systole the valve closed normally, but during diastole would only open when atrial pressure reached a level sufficient to overcome the frictional resistance imparted by the pannus. (bmj.com)
Relaxation phase1
  • The balloon rapidly inflates during the onset of diastole (the isometric or isovolumetric relaxation phase), as indicated by the dicrotic notch on the arterial waveform. (thefreedictionary.com)
Septal1
  • There was septal flattening in diastole, suggestive of raised ventricular pressures. (bmj.com)
Pulse1
  • Thus, we have a lot of Systole-, Diastole-, Pulse Pressure-, and Pulse-Values important for a medical doctor treating sick patients. (maplesoft.com)
Velocity1
  • The relatively constant blood flow during the diastole might predict more closely blood cell velocity in the capillary bed. (bmj.com)
Cephalad1
  • During diastole, blood fills the veins and moves cephalad with each heartbeat. (lexico.com)
Ventricle5
  • When, in late ventricular diastole , the atrial chambers contract, they send blood down to the larger, lower ventricle chambers. (wikipedia.org)
  • Peak filling rate normalized to peak ejection rate is a heart rate independent parameter which allows the performance of the patient's ventricle in diastole to be compared with its systolic function. (edu.au)
  • At the six-week visit, the echocardiograms showed that 48 patients (58.5 per cent) had dysfunction of the left ventricle of the heart at the point when it is relaxing and dilating (diastole). (indiatimes.com)
  • Projection of the mostly expanded area of the left ventricle (end diastole) is marked. (bme.hu)
  • And as the left ventricle fills with blood during diastole, the pressure within it rises. (osmosis.org)
Diastolic pressure1
  • Diastolic pressure, the bottom number, is the pressure during diastole, or the brief period of relaxation between heartbeats. (thefreelibrary.com)
Beats3
  • Harvey noted that the heart has two beats, the systole when it contracts and the diastole when it expands. (irishtimes.com)
  • It not only stretches the limits of a poet's metaphorical ability, but also creates an intra-poetic dialogue between the 'diastole' and 'systole' beats. (cordite.org.au)
  • Typically, images are collected during the fraction of a second that the heart rests between beats, a period called diastole. (acc.org)
Flow4
  • With isolated tubal torsion, the tube is usually distended and lacks flow or has reversed flow during diastole. (medscape.com)
  • Waveforms were consistent monophasic from CFA through pop with flow through diastole, no focal stenosis. (uvm.edu)
  • Quick Answer: Does blood flow during diastole? (ucaorta.org)
  • D wave - blood flow during passive period of LV diastole. (generalistultrasound.com)
Pressure1
  • Blood pressure is higher during systole and lower as the arteries relax during diastole. (smartimagebase.com)
Period2
  • This period of relaxation in the heart muscle is called diastole . (dummies.com)
  • With a slower rate, the resting period of the heart- the diastole- is prolonged. (yogamag.net)
Time2
  • Measurements were made on the driven strips of the Q-T interval, the conduction time, the maximal tension, the duration of systole, the effect of a single short diastole on the ensuing Q-T, the effect of different rates on Q-T, the relation of Q-T to the duration of systole and variations of the threshold to electric stimuli. (aspetjournals.org)
  • Diastole -- The rhythmic relaxation and dilation of the heart chambers, during which time they fill with blood (cf. systole). (nih.gov)
Pump1
  • Two players must pump a human heart by clicking two buttons in coordination: one acts as the systole movement, the other as the diastole. (globalgamejam.org)
Late2
  • An extra sound in late diastole suggests an S4 gallop (usually right ventricular). (medscape.com)
  • Here we compare STEAM and M2-SE DT-CMR in patients.Materials and methodsBiphasic DT-CMR using STEAM and M2-SE, late gadolinium imaging and pre/post gadolinium T1-mapping were performed in a mid-ventricular short-axis slice, in ten hypertrophic cardiomyopathy (HCM) patients at 3 T.ResultsAdequate quality data were obtained from all STEAM, but only 7/10 (systole) and 4/10 (diastole) M2-SE acquisitions. (imperial.ac.uk)
Sound1
Phase1
  • The leaflets open fully during the early rapid-filling phase of diastole. (medscape.com)
Wall1
  • Gates and et al (1999) compared the heart structure and function of elite male and female endurance skiers and observed that the LV end diastole, intra ventricular wall and post LV wall thicknesses and LV mass is significantly higher in male hearts [5]. (altorendimiento.com)
Short2
  • The dataset consisted of end-diastole and end-systole short-axis cine CMR images of 5,903 subjects from the UK Biobank database (61.5±7.1 years, 52% male, 81% white). (medrxiv.org)
  • Between them is a short break (systole) and a long break (diastole). (typepad.com)
Wie bemerke ich einen niedrigen Blutdruck?
Wie bemerke ich einen niedrigen Blutdruck? (dr-gumpert.de)
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Singularity by Marissa Davis - Poems | Academy of American Poets
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Takotsubo (Stress) Cardiomyopathy (Broken Heart Syndrome) Treatment & Management: Approach Considerations, Emergency Department... (medscape.com)
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Constrictive Pericarditis: Background, Pathophysiology, Etiology (medscape.com)
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Cardiogenic Pulmonary Edema Treatment & Management: Approach Considerations, Ventilatory Support, Preload Reduction (medscape.com)
DJ charts > Juno Recommends Electro > Electro Recommendations...
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Targeting cardiac fibrosis with engineered T cells | Nature
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Bicuspid Aortic Valve Workup: Laboratory Studies, Imaging Studies, Other Tests (emedicine.medscape.com)
Cardiac Calcification Imaging: Practice Essentials, Pericardial Calcifications, Myocardial Calcifications
Cardiac Calcification Imaging: Practice Essentials, Pericardial Calcifications, Myocardial Calcifications (emedicine.medscape.com)
Coronary CT Angiography: Practice Essentials, Overview, Clinical Applications: Coronary Artery Disease
Coronary CT Angiography: Practice Essentials, Overview, Clinical Applications: Coronary Artery Disease (medscape.com)
Coronary CT Angiography: Practice Essentials, Overview, Clinical Applications: Coronary Artery Disease
Coronary CT Angiography: Practice Essentials, Overview, Clinical Applications: Coronary Artery Disease (medscape.com)
Atrioventricular Nodal Reentry Tachycardia Workup: Approach Considerations, Electrocardiography, Electrophysiology
Atrioventricular Nodal Reentry Tachycardia Workup: Approach Considerations, Electrocardiography, Electrophysiology (medscape.com)
Aortic Dissection: Practice Essentials, Background, Anatomy
Aortic Dissection: Practice Essentials, Background, Anatomy (medscape.com)
Aortic Regurgitation: Background, Pathophysiology, Etiology
Aortic Regurgitation: Background, Pathophysiology, Etiology (medscape.com)
Heart Rate, Cardiac Phase Influence Perception of Time
Heart Rate, Cardiac Phase Influence Perception of Time (medscape.com)
Cas clinique: Syncope à l'effort chez un homme âgé
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Optison (Perflutren Protein-Type A Microspheres): Uses, Dosage, Side Effects, Interactions, Warning
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Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System
Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System (emedicine.medscape.com)
Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System
Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System (emedicine.medscape.com)