Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.
A process of selective diffusion through a membrane. It is usually used to separate low-molecular-weight solutes which diffuse through the membrane from the colloidal and high-molecular-weight solutes which do not. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Solutions prepared for exchange across a semipermeable membrane of solutes below a molecular size determined by the cutoff threshold of the membrane material.
Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
A membrane of squamous EPITHELIAL CELLS, the mesothelial cells, covered by apical MICROVILLI that allow rapid absorption of fluid and particles in the PERITONEAL CAVITY. The peritoneum is divided into parietal and visceral components. The parietal peritoneum covers the inside of the ABDOMINAL WALL. The visceral peritoneum covers the intraperitoneal organs. The double-layered peritoneum forms the MESENTERY that suspends these organs from the abdominal wall.
Catheters designed to be left within an organ or passage for an extended period of time.
Solutions prepared for hemodialysis. The composition of the pre-dialysis solution may be varied in order to determine the effect of solvated metabolites on anoxia, malnutrition, acid-base balance, etc. Of principal interest are the effect of the choice of buffers (e.g., acetate or carbonate), the addition of cations (Na+, K+, Ca2+), and addition of carbohydrates (glucose).
The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney.
Procedures which temporarily or permanently remedy insufficient cleansing of body fluids by the kidneys.
Devices which can substitute for normally functioning KIDNEYS in removing components from the blood by DIALYSIS that are normally eliminated in the URINE.
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
Elements of limited time intervals, contributing to particular results or situations.
The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.
The transference of a kidney from one human or animal to another.
Pathological processes of the KIDNEY or its component tissues.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Pathological processes involving the PERITONEUM.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Polysaccharides composed of repeating glucose units. They can consist of branched or unbranched chains in any linkages.
Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.
State of the body in relation to the consumption and utilization of nutrients.
Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.
The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.
KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.
A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.
Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
Disturbances in the body's WATER-ELECTROLYTE BALANCE.
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
The two dimensional measure of the outer layer of the body.
The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Extracorporeal ULTRAFILTRATION technique without HEMODIALYSIS for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.
A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Health care institutions operated by private groups or corporations for a profit.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Withholding or withdrawal of a particular treatment or treatments, often (but not necessarily) life-prolonging treatment, from a patient or from a research subject as part of a research protocol. The concept is differentiated from REFUSAL TO TREAT, where the emphasis is on the health professional's or health facility's refusal to treat a patient or group of patients when the patient or the patient's representative requests treatment. Withholding of life-prolonging treatment is usually indexed only with EUTHANASIA, PASSIVE, unless the distinction between withholding and withdrawing treatment, or the issue of withholding palliative rather than curative treatment, is discussed.
Fluids composed mainly of water found within the body.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Inorganic salts of phosphoric acid.
Pathologic deposition of calcium salts in tissues.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
The destroying of all forms of life, especially microorganisms, by heat, chemical, or other means.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Devices to be inserted into veins or arteries for the purpose of carrying fluids into or from a peripheral or central vascular location. They may include component parts such as catheters, ports, reservoirs, and valves. They may be left in place temporarily for therapeutic or diagnostic purposes.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Organizational activities previously performed internally that are provided by external agents.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
An imbalanced nutritional status resulted from insufficient intake of nutrients to meet normal physiological requirement.
A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).
The rate dynamics in chemical or physical systems.
The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.
A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
Directions written for the obtaining and use of PHARMACEUTICAL PREPARATIONS; MEDICAL DEVICES; corrective LENSES; and a variety of other medical remedies.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Infections by bacteria, general or unspecified.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
A biochemical abnormality referring to an elevation of BLOOD UREA NITROGEN and CREATININE. Azotemia can be produced by KIDNEY DISEASES or other extrarenal disorders. When azotemia becomes associated with a constellation of clinical signs, it is termed UREMIA.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
Water-soluble proteins found in egg whites, blood, lymph, and other tissues and fluids. They coagulate upon heating.
Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
The resistance to the flow of either alternating or direct electrical current.
The confinement of a patient in a hospital.
The balance between acids and bases in the BODY FLUIDS. The pH (HYDROGEN-ION CONCENTRATION) of the arterial BLOOD provides an index for the total body acid-base balance.
A double-layered fold of peritoneum that attaches the STOMACH to other organs in the ABDOMINAL CAVITY.
Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Catheters that are inserted into a large central vein such as a SUBCLAVIAN VEIN or FEMORAL VEIN.
A species of STAPHYLOCOCCUS that is a spherical, non-motile, gram-positive, chemoorganotrophic, facultative anaerobe. Mainly found on the skin and mucous membrane of warm-blooded animals, it can be primary pathogen or secondary invader.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
A fetuin subtype that is synthesized by HEPATOCYTES and secreted into the circulation. It plays a major role in preventing CALCIUM precipitation in the BLOOD.
A highly poisonous compound used widely in the manufacture of plastics, adhesives and synthetic rubber.
Solution that is usually 10 percent glucose but may be higher. An isotonic solution of glucose is 5 percent.
A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster's New Geographical Dictionary, 1988, p842 & Room, Brewer's Dictionary of Names, 1992, p378)
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Prospective patient listings for appointments or treatments.
An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
A collection of watery fluid in the pleural cavity. (Dorland, 27th ed)
Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
The presence of an infectious agent on instruments, prostheses, or other inanimate articles.
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
The degree to which BLOOD VESSELS are not blocked or obstructed.
Death of cells in the KIDNEY CORTEX, a common final result of various renal injuries including HYPOXIA; ISCHEMIA; and drug toxicity.
Methods of creating machines and devices.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.
The actual costs of providing services related to the delivery of health care, including the costs of procedures, therapies, and medications. It is differentiated from HEALTH EXPENDITURES, which refers to the amount of money paid for the services, and from fees, which refers to the amount charged, regardless of cost.
Removal of an implanted therapeutic or prosthetic device.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
General dysfunction of an organ occurring immediately following its transplantation. The term most frequently refers to renal dysfunction following KIDNEY TRANSPLANTATION.
Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.
Diseases of BONES.
Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed)
A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Substances that reduce the growth or reproduction of BACTERIA.
Institutions which provide medical or health-related services.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
A technique of measuring the dielectric properties of materials, which vary over a range of frequencies depending on the physical properties of the material. The technique involves measuring, over a range of frequencies, ELECTRICAL IMPEDANCE and phase shift of an electric field as it passes through the material.
The fluid of the body that is outside of CELLS. It is the external environment for the cells.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Proteins prepared by recombinant DNA technology.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
The study of chance processes or the relative frequency characterizing a chance process.
A sugar acid derived from D-glucose in which both the aldehydic carbon atom and the carbon atom bearing the primary hydroxyl group are oxidized to carboxylic acid groups.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.
Patient or client refusal of or resistance to medical, psychological, or psychiatric treatment. (APA, Thesaurus of Psychological Index Terms, 8th ed.)
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
An independent sultanate on the northeast coast of Borneo. Its chief products are oil and natural gas. Its name is Hindi, coming from the Sanskrit bhumi, land or region. It gave its name Brunei to Borneo. (From Webster's New Geographical Dictionary, 1988, p183 & Room, Brewer's Dictionary of Names, 1992, p82)
Infections with bacteria of the genus STAPHYLOCOCCUS.
Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.
A dead body, usually a human body.
Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.
Refusal of the health professional to initiate or continue treatment of a patient or group of patients. The refusal can be based on any reason. The concept is differentiated from PATIENT REFUSAL OF TREATMENT see TREATMENT REFUSAL which originates with the patient and not the health professional.
The teaching or training of patients concerning their own health needs.
The presence of organisms, or any foreign material that makes a drug preparation impure.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.
Obstruction of flow in biological or prosthetic vascular grafts.
A topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.
A disease or state in which death is possible or imminent.
The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
Transmission of energy or mass by a medium involving movement of the medium itself. The circulatory movement that occurs in a fluid at a nonuniform temperature owing to the variation of its density and the action of gravity. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed; Webster, 10th ed)

Evaluation of a new method for the analysis of free catecholamines in plasma using automated sample trace enrichment with dialysis and HPLC. (1/1315)

BACKGROUND: Analysis of urinary free catecholamines was automated recently, but analysis of plasma samples posed special difficulties. The present study was undertaken to evaluate a new method for the automated analysis of plasma catecholamines. METHODS: The procedure is based on an improved sample handling system that includes dialysis and sample clean-up on a strong cation trace-enrichment cartridge. The catecholamines norepinephrine, epinephrine, and dopamine are then separated by reversed-phase ion-pair chromatography and quantified by electrochemical detection. RESULTS: Use of a 740- microL sample is required to give the catecholamine detection limit of 0.05 nmol/L and analytical imprecision (CV) between 1.1% and 9.3%. The assay can be run unattended, although >12 h of analysis time is not recommended without cooling of the autosampler rack. Comparison (n = 68) of the automated cation-exchange clean-up with the well-established manual alumina procedure gave excellent agreement (mean, 3.78 +/- 2.76 and 3.8 +/- 2.89 nmol/L for norepinephrine and 0.99 +/- 1.72 and 1.08 +/- 1.78 nmol/L for epinephrine). Hemodialysis had no clear effect on plasma norepinephrine. Epinephrine concentrations were similar (0.05 < P < 0.1) in chronic renal failure patients (0.24 +/- 0.3 nmol/L; n = 15) and healthy controls (0.5 +/- 0.24 nmol/L; n = 31). Dopamine was not quantified, being usually <0.2 nmol/L. CONCLUSION: The availability of such a fully automated procedure should encourage the more widespread use of plasma catecholamine estimation, e.g., after dialysis, exercise, or trauma/surgery and in the investigation of catecholamine-secreting tumors, particularly in the anuric patient.  (+info)

Inhibition of protein denaturation by fatty acids, bile salts and other natural substances: a new hypothesis for the mechanism of action of fish oil in rheumatic diseases. (2/1315)

Natural hydrophobic substances like bile salts (cholate, deoxycholate, chenodeoxycholate, lithocholate and their conjugates with glycine and taurine), fatty acids (caprylic, capric, lauric, myristic, palmitic, stearic, oleic, linoleic, arachidonic, eicosapentaenoic and docosahexaenoic acid) were much more active (EC50 approximately 10(-4)-10(-5) M) than selected amino acids (EC50 > 10(-2) M) and inorganic salts (EC50 approximately 10(-1) M) in inhibiting heat-induced denaturation of human serum albumin in vitro. Fish oil, rich in n-3-polyunsaturated acids such as eicosapentaenoic acid and docosahexaenoic acid, administered p.o. (1 ml/kg) in the rat, protected ex vivo (after 2 hr) serum against heat-induced denaturation more than bendazac, a known antidenaturant drug. Thus, we speculated that the antidenaturant activity of fish oil may be partly (in addition to the known effect on endogenous eicosanoid composition) responsible for its beneficial effects in rheumatoid arthritis and other rheumatic conditions. In this connection, it is of note that the in vitro antidenaturant activity of fish oil fatty acids was higher than that of known antidenaturant drugs such as bendazac and bindarit and nonsteroidal anti-inflammatory drugs like phenylbutazone and indomethacin which could exert beneficial effects in chronic inflammatory conditions by stabilizing endogenous proteins.  (+info)

Kinetics and mechanism of exchange of apolipoprotein C-III molecules from very low density lipoprotein particles. (3/1315)

Transfer of apolipoprotein (apo) molecules between lipoprotein particles is an important factor in modulating the metabolism of the particles. Although the phenomenon is well established, the kinetics and molecular mechanism of passive apo exchange/transfer have not been defined in detail. In this study, the kinetic parameters governing the movement of radiolabeled apoC molecules from human very low density lipoprotein (VLDL) to high density lipoprotein (HDL3) particles were measured using a manganese phosphate precipitation assay to rapidly separate the two types of lipoprotein particles. In the case of VLDL labeled with human [14C]apoCIII1, a large fraction of the apoCIII1 transfers to HDL3 within 1 minute of mixing the two lipoproteins at either 4 degrees or 37 degrees C. As the diameter of the VLDL donor particles is decreased from 42-59 to 23-25 nm, the size of this rapidly transferring apoCIII1 pool increases from about 50% to 85%. There is also a pool of apoCIII1 existing on the donor VLDL particles that transfers more slowly. This slow transfer follows a monoexponential rate equation; for 35-40 nm donor VLDL particles the pool size is approximately 20% and the t1/2 is approximately 3 h. The flux of apoCIII molecules between VLDL and HDL3 is bidirectional and all of the apoCIII seems to be available for exchange so that equilibrium is attained. It is likely that the two kinetic pools of apoCIII are related to conformational variations of individual apo molecules on the surface of VLDL particles. The rate of slow transfer of apoCIII1 from donor VLDL (35-40 nm) to acceptor HDL3 is unaffected by an increase in the acceptor to donor ratio, indicating that the transfer is not dependent on collisions between donor and acceptor particles. Consistent with this, apoCIII1 molecules can transfer from donor VLDL to acceptor HDL3 particles across a 50 kDa molecular mass cutoff semipermeable membrane separating the lipoprotein particles. These results indicate that apoC molecules transfer between VLDL and HDL3 particles by an aqueous diffusion mechanism.  (+info)

Isolation and characterization of a Ca2+ -binding polysaccharide associated with coccoliths of Emiliania huxleyi (Lohmann) Kamptner. (4/1315)

C-occolithophoridae, a group of mostly unicellular algae, possess a cell wall containing calcified plates, called coccoliths. The coccoliths from the species Emilania huxleyi (Lohmann) Kamptner contain a water-soluble acid polysaccharide. In this paper we describe the isolation and some characteristic properties of the polysaccharide, in particular its Ca2+ -binding capacity. A large-scale cultivation of the Coccolithophoridae was worked out and a new procedure for isolating coccoliths was developed. The polysaccharide obtained from the coccoliths contained two types of monobasic acid groups in a total amount of 1.8 mumol/mg polysaccharide. One type consisted of weakly acid groups which were identified as uronic acids. The nature of the stronger acid groups remains to be established. The ratio between the respective groups was 1:0.8. Studies with 45Ca2+ demonstrated that the isolated polysaccharide is capable of binding Ca2+. Equilibrium dialysis revealed that the maximum amount of Ca2+ which can be bound in 0.92 +/- 0.05 mumol/mg polysaccharide. Flow-rate dialysis experiments strongly suggested the presence of two classes of Ca2+ -binding sites differing in affinity for Ca2+. High-affinity sites (dissociation constant Kd for Ca2+ :2.2 +/- 1.0 X 10(-5) M) were found to be present in amounts (0.38 +/- 0.04 mumol/mg polysaccharide) approximately equivalent to the strongly acid monovalent groups mentioned above (0.8 mumol/mg polysaccharide). Low-affinity sites (Kd for Ca2+: -11 +/- 39 X 10(-5) M) were estimated at 0.74 +/- 0.11 mumol/mg polysaccharide. Although this figure could be determined less accurately, it is suggested that the uronic acids (1.0 mumol/mg polysaccharide) are identical to the low-affinity sites. Preferential binding of Ca2+ occurred in a 100-fold excess of Na+ and Mg2+ as was shown by gel filtration. A 100-fold excess of Sr2+ inhibited Ca2+ binding to a great extent while no Ca2+ was bound in the presence of an equimolar amount of La3+. The dissociation constants of the high-affinity sites for Na+, Mg2+, Sr2+ and La3+ (in the presence of Ca2+) were determined with the flow-rate dialysis technique. They confirm the order of binding preference found with gel filtration. A polysaccharide with similar properties could be isolated from subfossil coccoliths of E. hyxleyi (about 1000 years old). The possible role of the polysaccharide as a heterogeneous matrix in coccolith formation is discussed.  (+info)

Polyamine-dependent deoxyribonuclease activity from rat-liver nuclei. (5/1315)

When nuclei isolated from rat liver in a low salt buffer were washed with 0.1 M NaCl solution, the supernatant showed a deoxyribonuclease (DNase) activity. The activity required Mg2+ and in addition spermine or spermidine, and its optimal pH was 7.2-7.4. The activity was higher on denatured (single stranded) DNA than on double-helical DNA. With both substrates the activity was highest at a polyamine concentration at which the DNA-polyamine complex began to precipitate. No Mg2++Ca2+ dependent DNase activity was detected in the preparation.  (+info)

Tissue distribution and characteristics of xanthine oxidase and allopurinol oxidizing enzyme. (6/1315)

Tissue distribution and levels of allopurinol oxidizing enzyme and xanthine oxidase with hypoxanthine as a substrate were compared with supernatant fractions from various tissues of mice and from liver of mice, rats, guinea pigs and rabbits. The allopurinol oxidizing enzyme activities in liver were quite different among the species and the sex difference of the enzyme activity only in mouse liver. In mice, the highest activity of allopurinol oxidizing enzyme was found in the liver with a trace value in lung, but the enzyme activity was not detected in brain, small intestine and kidney, while the highest activity of xanthine oxidase was detected in small intestine, lung, liver and kidney in that sequence. The allopurinol oxidizing enzyme activity in mouse liver supernatant fraction did not change after storage at -20 degrees C or dialysis against 0.1 M Tris-HCl containing 1.15% KCl, but the activity markedly decreased after dialysis against 0.1 M Tris-HCl. On the contrary, the xanthine oxidase was activated 2 to 3 times the usual activity after storage at -20 degrees C or dialysis of the enzyme preparation. These results indicated that allopurinol was hydroxylated to oxipurinol mainly by the enzyme which is not identical to xanthine oxidase in vivo. A possible role of aldehyde oxidase involved in the allopurinol oxidation in liver supernatant fraction was dicussed.  (+info)

Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells. (7/1315)

NSF and alpha-SNAP have been shown to be required for SNARE complex disassembly and exocytosis. However, the exact requirement for NSF and alpha-SNAP in vesicular traffic through the secretory pathway remains controversial. We performed a study on the kinetics of exocytosis from bovine chromaffin cells using high time resolution capacitance measurement and electrochemical amperometry, combined with flash photolysis of caged Ca2+ as a fast stimulus. alpha-SNAP, a C-terminal mutant of alpha-SNAP, and NEM were assayed for their effects on secretion kinetics. Two kinetically distinct components of catecholamine release can be observed upon fast step-like elevation of [Ca2+]i. One is the exocytotic burst, thought to represent the readily releasable pool of vesicles. Following the exocytotic burst, secretion proceeds slowly at maintained high [Ca2+]i, which may represent vesicle maturation/recruitment, i.e. some priming steps after docking. alpha-SNAP increased the amplitude of both the exocytotic burst and the slow component but did not change their kinetics, which we examined with millisecond time resolution. In addition, NEM only partially inhibited the slow component without altering the exocytotic burst, fusion kinetics and the rate of endocytosis. These results suggest a role for alpha-SNAP/NSF in priming granules for release at an early step, but not modifying the fusion of readily releasable granules.  (+info)

Daunomycin-induced unfolding and aggregation of chromatin. (8/1315)

Using equilibrium dialysis and sedimentation velocity analysis, we have characterized the binding of the anti-tumor drug daunomycin to chicken erythrocyte chromatin before and after depletion of linker histones and to its constitutive DNA under several ionic strengths (5, 25, and 75 mM NaCl). The equilibrium dialysis experiments reveal that the drug binds cooperatively to both the chromatin fractions and to the DNA counterpart within the range of ionic strength used in this study. A significant decrease in the binding affinity was observed at 75 mM NaCl. At any given salt concentration, daunomycin exhibits higher binding affinity for DNA than for linker histone-depleted chromatin or chromatin (in decreasing order). Binding of daunomycin to DNA does not significantly affect the sedimentation coefficient of the molecule. This is in contrast to binding to chromatin and to its linker histone-depleted counterpart. In these instances, preferential binding of the drug to the linker DNA regions induces an unfolding of the chromatin fiber that is followed by aggregation, presumably because of histone-DNA interfiber interactions.  (+info)

Comparison of the Effects of Dialysis Methods (Haemodialysis Peritoneal Dialysis) on Diastolic Left Ventricular Function Dialysis Methods and Diastolic Function
Abstract: Photosystem II (PSII), which produces oxygen using light energy, requires Cl- as a cofactor. Cl- appears to be difficult to remove from PSII because there always remains residual activity of 25-40%. We have tested variations of the dialysis method to deplete PSII of Cl- by introducing NO3- or Br- before dialysis. NO3 pretreatment produced a preparation with suppressed activation by NO3-, suggesting that NO3- replaced Cl- at its site of activation. Br- pretreatment produced the preparation with the lowest residual activity and the highest total activity, indicating that it was the best method for Cl- depletion. The electron paramagnetic resonance (EPR) multiline signal from the S2 state was examined in the presence of Cl-, Br- and NO3- in the Cl- depleted PSII pretreated with NO3-. The signal height followed the same trend as oxygen evolution activity with Cl- > Br- > no anion > NO3.--Abstract from author supplied metadata.. Investigation of dialysis methods for the complete removal ...
Define electrodialysis. electrodialysis synonyms, electrodialysis pronunciation, electrodialysis translation, English dictionary definition of electrodialysis. n. pl. e·lec·tro·di·al·y·ses Dialysis at a rate increased by the application of an electric potential across the dialysis membrane, used especially to...
TY - JOUR. T1 - Normal free thyroxine in critical nonthyroidal illnesses measured by ultrafiltration of undiluted serum and equilibrium dialysis. AU - Surks, Martin I.. AU - Hupart, K. H.. AU - Pan, C.. AU - Shapiro, L. E.. PY - 1988. Y1 - 1988. N2 - Considerable controversy exists concerning the assessment of thyroidal state in critically ill patients with decreased serum T4 and T3 concentrations, in part because serum free T4 values are often low in such patients no matter what method of measurement is used. We developed an ultrafiltration method to measure free T4 and free T3 in undiluted serum and compared the results with those obtained using a standard equilibrium dialysis method to measure free T4 and T3. In 30 consecutive intensive care unit (ICU) patients, serum free T4 values were similar to or higher than those in 12 normal subjects by both methods in most patients and were clearly distinguishable from those in hypothyroid patients. The serum total T4 concentrations in these patients ...
It should be emphasized that the array of structures listed in Table 1 are but a point of departure. The competition dialysis method is completely general, and arrays of structures of particular interest can be designed as desired. The only limitations are that the structures be large enough to be retained by the dialysis tubing chosen for use, and that they are verified to be stable under the ionic conditions of the experiment. Essential quality control experiments to characterize nucleic acid samples were described in detail [41, 42] and include UV absorbance and circular dichroism spectroscopy, and thermal denaturation studies. Fig. 1 Schematic of the competition dialysis experiment. A schematic representation of the structures used is shown on the left. The center shows the simple experimental setup, a beaker containing the test ligand solution and the holder for the dialysis units. A schematic of the microdialysis unit is shown on the right Structural Selectivity of Drug-Nucleic Acid ...
SnakeSkin Dialysis Tubing was developed to simplify large-volume sample dialysis and does not require presoaking or boiling the membrane prior to use. SnakeSkin Dialysis Tubing is regenerated cellulose dialysis tubing that is pleated (compressed) into a hollow stick and can be used for a wide range of sample volumes. The hydrated tubing will hold ~3.7 mL of sample per centimeter of length.. The pleated format of SnakeSkin Dialysis Tubing makes it easy to open and ready to use; simply pull out the required length of tubing, cut it off and apply a closure. The recommended closures, SnakeSkin Dialysis Tubing Clips, are sold separately. Alternatively, SnakeSkin Dialysis Tubing can also be closed with knots after prewetting the tubing in water or buffer.. SnakeSkin Dialysis Tubing is available in three molecular weight cutoff (MWCO) specifications: 3.5K, 7K and 10K.. ...
D5091-95(2014) Standard Guide for Water Analysis for Electrodialysis/Electrodialysis Reversal Applications electrodialysis reversal~ water analysis~
Shop a large selection of General Dialysis Supplies products and learn more about Spectrum™ Universal Dialysis Tubing Closures (for all Membrane Types) Black; 50mm
Spectra/Por Dialysis Tubing, Regenerated Cellulose, MWCO 12000 to 14000, Spectrum Laboratories : Standard dialysis tubing for all laboratory dialysis
electrodialysis for gold refining_electrodialysis for gold refining - Grinding Mill ChinaThe Gulin product line, consisting of more than 30 machines, sets the standard for our industry. We plan to help you meet your needs wit
SnakeSkin Tubing Clips - Pierce SnakeSkin Pleated Dialysis Tubing, MWCO 3500 to 10000, : Simplifies dialysis of sample volumes between 15mL and 100m
The present invention provides an improved peritoneal dialysis method and system. The system comprises a single catheter that is placed in the patient, a source of dialysate, and a diatyzer in fluid communication with the source of dialysate and the catheter. The system includes a single fluid pump in fluid communication with the source of dialysate and the catheter. The single pump is capable of pumping the dialysate into and out of the patient and back to the source of dialysate. The method includes the steps of placing a single catheter in a peritoneum of the patient, providing a source of dialysate, coupling the source of dialysate in fluid communication with the catheter on a single fluid circuit, pumping the dialysate from the source of dialysate into and out of the peritoneum using a single pump in the single fluid circuit.
Specially designed with gentle sealing ridges, Universal Closures are the ideal all-purpose closure that creates a reliable seal with all membrane grades, types and thicknesses. Available in a variety of colors for easy sample identification. For best results, select a pair of closures that has a sealing width 4 to 10 mm longer than the flat width of the dialysis tubing. This assures a proper seal without membrane tearing.
Monday, Dr Lauré Adrien, Director General of the Ministry of Public Health, presented the advances of the dialysis methods and the plan of fight against the diphtheria...
Herein, 1F2, an anti-HER2 monoclonal antibody (mAb), was covalently combined to the top of 5-Fluorouracil (5-FU) packed bovine serum albumin (BSA) nanoparticles. can effectively be used for targeted delivery of 5-FU to HER2-positive cancerous cells. cumulative release of 5-FU was examined. Brief and long-term physicochemical and natural balance of 1F2-combined 5-FU-loaded BSA nanoparticles had been looked into during 72 hours and 90 days of storage space, respectively. Finally, the cytotoxicity and specificity of BSA nanoparticles, free of charge medication, 5-FU-loaded BSA nanparticles, 5-FU-loaded PEGylated BSA nanoparticles and 1F2-combined BSA nanoparticles evaluated on SKBR3 and MCF7 cancerous cells and compared with 1F2-coupled 5-FU-loaded BSA nanoparticles. Experimental cumulative release behavior Rabbit Polyclonal to DMGDH. of 5-FU from BSA nanoparticles, PEGylated BSA nanoparticles and 1F2-coupled BSA nanoparticles was evaluated during a period of 50 hours using dialysis method. The ...
Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsulate the plasmid and are serum-stable.
abstractNote = {In vivo studies in mice injected intravenously with /sup 125/I-triiodothyronine (T-3) showed a linear relationship between the uptake of the labelled hormone by the tissue and the lipid phosphorous content of the same tissue. However, studies with /sup 125/I-thyroxine failed to show a similar relationship between the lipid phosphorous content of the organ and the uptake of radioactive hormone by the same organ. In vitro studies using equilibrium dialysis technique with isolated lipid extracts of various organs and radioactive thyroid hormones (T-3 and T-4) did not show any relation between the lipid P and the uptake of labelled hormone. On the basis of the observed discrepancy between in vivo and in vitro studies, it is postulated that an organized lipoprotein structure at the cell membrane may be responsible for the entry of the thyroid hormones ...
April 29, 1969 E. .1. SERFASS ET CONTROLLED BLOOD DIALYSIS SYSTEM Filed July 7, 1966 sheet I of 7 F I TEMPERATURE I 25\ VENOU.$ U ann- R LONCENTRATIDN PREssuzE MON TOR M\OR WASTE [Z6 NEGATIVE PRESSURE MomToz TO DRAlN \9 ou-rFLow 27 Mom-r02 1.96m. UN\T I 29 57 LOW NORMAL man START d OM1 b T 3.2 0 9 TEMPERATURE 39 44 ser PO\NT muse: 30 44a. 44b To? DIALYSKTE d DI ALYSlS cone. 6 6 32 40 5b 45 c sremuu mscountcr 45a. 4 5, 5 AUD BLE G gg flgfid pzessuzeG d ALARM can 54 4, 005 46a 5 45b Q-5o C6 mNsE n d) Pz gsuze ACrWATE. ALARM 35 4 e, 49 47 5ILENCE TEST 7 d sTEmuzE n C) (f d (6 I LAMP 955T cuff-LOW 5 covmEc-r 57 FAH-UIZE H H BLOOP L045! ALL 51-0? (5 36 OUTFLOW TEMP. cone. veuov: Puss. NEG. Puss, . con-ram. 1 W T Q (Q w April 29, 1969 E. J. SERFASS ET AL 3,441,136 CONTROLLED BLOOD DIALYSIS SYSTEM Sheet Filed July 7; 1966 nfi 22mm 8 ...l\ xu fi KoPdJOm L @NL m E 3 1 n 8 flaw NM, Ommg 5. m Pzw L m I L Vwm s2 d R 2. B KmP A 2 m9 32 $2? 2 9. (2. m2 MM; flNNf 5 m: 6: H 24k IL 3; 6mm I; MW umfiv o: ...
The Dialysis Techniques course is a certification course that focuses primarily on dialysis techniques and procedures. It is a lucrative course that students can take after successfully passing the 10+2… Read more » ...
Abstract:This paper presents a systematic techno-economical analysis and an environmental impact evaluation of a reverse osmosis (RO) concentrate treatment process using electrodialysis (ED) in view of environmental management of brine discharges. The concentrate originates from a secondary effluent treated by RO. Without any treatment, the concentrate would have to be discharged; this is compared in this study to the costs and benefits of an effective treatment method in a pilot scale ED plant. A technical analysis was done both on lab scale and pilot scale for the determination of operational and maintenance costs for the ED installation at the required conditions of process performance and safety. Subsequently, an economical analysis was done to calculate the cost of the different parts of the ED system. It was shown that an operational cost of 0.19 EUR m−3 can be achieved, assuming that the ED concentrate is to decarbonated at pH 6.0 to prevent membrane scaling. Finally, environmental ...
This device reduces difficulties in handling dialysis bags. Dialysis tubing is cut to length and knotted at the end. The other end is slipped onto the tube and held with silicone rubber loops F20308, or a rubber band. Three tube steps fit various sizes of dialysis tubing and a three notched universal hanger supports the funnel on the edge of any vessel. Also features a captive cap with writing area. Steam autoclavable at 121ºC (250ºF). 10 per bag.
Packed dry , made from regenerated cellulose (RC). With glycerol as protection for embrittlement, which can be easily removed by soaking in water. Contain low level of heavy metal and sulfide impurities. Highly resistant against chemicals, suitable for pH range 2 - 12 and temperatures 4 - 60 °C.
Economy packaging provides a 10-meter supply of a particular CE tubing MWCO & flatwidth to meet the demands of ongoing & frequent dialysis applications. Product Specifications: Properties: Hydrophilic, symmetric porosity 9 MWCOs: 100-500 D, 500-1000 D, 3.5-5 kD, 8-10 kD, 20 kD, 50 kD, 100 kD, 300 kD & 1000 kD 4 Flat Widths: 10 mm, 16 mm, 24 mm & 31 mm Qty & Pkg: 10 meter/roll, wet in 0.05% sodium azide
Dialysis Systems | Sample dialysis | Dialyzer | Laboratory dialysis | Sample Preparation | Dialysis Tubings | Dialysis Accessories | Micro Dialyzer
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Cardiovascular disease is the number one killer of patients with chronic kidney disease (CKD), and insulin resistance - a lowered level of response to insulin circulating in the blood - is an important cardiovascular risk factor in these patients. Its not clear why patients with CKD often develop insulin resistance, but the retention of compounds that are normally removed from the blood and excreted in the urine may play a role. One such compound is p-cresyl sulfate (PCS), a toxin that is produced by gut bacteria. PCS is retained in CKD patients, and it is poorly removed by most dialysis techniques.. Read more. ...
A better understanding of the pathophysiology of renal failure coupled with technological advances in dialysis techniques and renal transplantation have greatly improved the prognosis and survival for patients with end-stage renal disease (ESRD). Unfortunately, the advances and success of treatment are limited by a number of extrarenal complications that can cause significant morbidity and mortality.
A better understanding of the pathophysiology of renal failure coupled with technological advances in dialysis techniques and renal transplantation have greatly improved the prognosis and survival for patients with end-stage renal disease (ESRD). Unfortunately, the advances and success of treatment are limited by a number of extrarenal complications that can cause significant morbidity and mortality.
PURPOSE: To minimize the consumptions of condensed dialysis solution, make-up water and energy and to reduce a cost of dialytic treatment without lowering the dialytic quality, by installing a control unit to feed the signals directed from the blood flow volume into the input side of the unit, from whose output side the signals as functions of blood flow volume are sent out into the system to adjust the flow of dialytic solution. CONSTITUTION: An automatically-operated type control circuit is included in the control unit 100. A signal led from a blood flow rate is sent into the input port of this control unit. The signal is, therefore, led from a feeding flow volume set for a blood pump 30, that is, led from a revolution velocity (RPM) of the blood pump 30, for instance. The flow volume of dialytic solution is automatically adjusted, based on the output signals of the control unit. For this purpose, the output of control circuit 100 is connected either to the dialytic solution pump 20 or
As the pioneer and leader in laboratory dialysis products, Repligen offers the largest selection of dialysis membranes, ready to use devices, and dynamic dialysis systems
डॉ. संजय पंडया आणि डॉ . ज्योत्स्ना झोपे यांचे लोकप्रिय पुस्तक सुरक्षा किडणी ची माहिती आता वेबसाईट च्या रुपात आपल्याला मिळेल . किडणी फेल्योर ची संख्या खूपच वाढत आहे पण सामान्य जनतेला या रोगाविषयी काहीच माहिती नाही. जेव्हा किडणी खराब होते तेव्हा डायलिसिस आणि किडणी प्रत्यारोपण असे महागडे उपचार करावे लागतात. भारतासारख्या विकासप्रधान देशात १०% रुग्णच असे महागडे उपचार करू शकतात. यामुळे
Elderly patients with kidney failure may not gain the same benefits from whats considered the gold standard for accessing the blood for dialysis compared with younger patients, according to a study appearing in an upcoming ...
The simplest would be to cut out the band and place it in dialysis tubing, and re-electrophorese. Visualizing the band before excising will require picking the right dye and avoiding conditions that would fix the protein (methanol, acetic acid). Not sure if ponceau would work. Also, choose a low MW cut off for the tubing because SDS will denature the protein, making it easier to slither through the pores ...
Outset Medical has raised a $76.5m in a Series C funding round that it plans to use to extend the use of its portable kidney dialysis system.
The Dangers Of Granuflo GranuFlo is a substance frequently used in kidney dialysis procedures, counteracting the harmful effects of acids and others
Currently, numerous studies are focused on the valorisation of seawater desalination reverse osmosis brines. Electrodialysis can be used to concentrate one of the primary components (NaCI) and obtain a suitable raw material for industrial applications, such as the chlor-alkali industry. An electrodialysis pilot plant was used to evaluate the efficiency of concentrating a seawater reverse osmosis (SWRO) brine under representative full-scale operational conditions covering the temperature range of a semiarid climate. The results indicate that electrodialysis is a technology that can concentrate SVVRO brines from approximately 70 to 245 g/L NaCl, achieving an additional intrinsic purification of major multivalent ions (Ca2+, Mg2+, SO42-) due to the selectivity patterns of ion exchange membranes and the ion-complexation reactions in the concentrated brines. However, minor components, such as Ni and Cu, are concentrated due to the formation of Cu and Ni complexes with chloride ions to form ...
TY - JOUR. T1 - Salinity-gradient power: Evaluation of pressure-retarded osmosis and reverse electrodialysis. AU - Post, J.W.. AU - Veerman, J.. AU - Hamelers, H.V.M.. AU - Euverink, G.J.W.. AU - Metz, S.J.. AU - Nymeijer, K.. AU - Buisman, C.J.N.. PY - 2007. Y1 - 2007. N2 - A huge potential to obtain clean energy exists from mixing water streams with different salt concentrations. Two membrane-based energy conversion techniques are evaluated: pressure-retarded osmosis and reverse electrodialysis. From the literature, a comparison is not possible since the reported performances are not comparable. A method was developed which allows for a comparison of both techniques at equal conditions, with respect to power density and energy recovery. Based on the results from the model calculations, each technique has its own field of application. Pressure-retarded osmosis seems to be more attractive for power generation using concentrated saline brines because of the higher power density combined with ...
Searching for Dialysis Tubing Market to Witness Massive growth ahead | Sigma-Aldrich, Thermo Fisher Scientific, SERVA Electrophoresis GmbH We got you covered at iCrowdNewswire.
Polymeric micelles self-assembled from cholesterol-conjugated poly(ethylene glycol) (PEG) and anchored with transcriptional activator TAT peptide (TAT-PEG-b-Col) were fabricated for delivery of antibiotics across the blood-brain barrier (BBB). Ciprofloxacin, which demonstrated a high bactericidal effect, was efficiently loaded into the micelles by a membrane dialysis method. The ciprofloxacin-loaded micelles were characterized via dynamic light scattering and SEM. The micelles were spherical in nature, having an average diameter of smaller than 180 nm. Sustained release of ciprofloxacin was achieved over 6 h in phosphate-buffered saline (pH 7.4) at 37°C. Confocal laser scanning microscopy reveals that the uptake of Fluorescein 5-isothiocyanate (FITC)-loaded TAT-PEG-b-Col micelles by human astrocytes was much higher than that of free FITC. Animal studies proved that these micelles crossed the BBB and entered the brain. The TAT-conjugated micelles may be used to deliver antibiotics across the BBB ...
Nanotechnology has provided the possibility of delivering drugs to specific cells using nanoparticles.[9] The overall drug consumption and side-effects may be lowered significantly by depositing the active agent in the morbid region only and in no higher dose than needed. Targeted drug delivery is intended to reduce the side effects of drugs with concomitant decreases in consumption and treatment expenses. Drug delivery focuses on maximizing bioavailability both at specific places in the body and over a period of time. This can potentially be achieved by molecular targeting by nanoengineered devices.[10][11] A benefit of using nanoscale for medical technologies is that smaller devices are less invasive and can possibly be implanted inside the body, plus biochemical reaction times are much shorter. These devices are faster and more sensitive than typical drug delivery.[12] The efficacy of drug delivery through nanomedicine is largely based upon: a) efficient encapsulation of the drugs, b) ...
Power production from microbial reverse electrodialysis cell (MRC) electrodes is substantially improved compared to microbial fuel cells (MFCs) by using ammonium bicarbonate (AmB) solutions in multiple RED cell pair stacks and the cathode chamber. Reducing the number of RED membranes pairs while maintaining enhanced electrode performance could help to reduce capital costs. We show here that using only a single RED cell pair (CP), created by operating the cathode in concentrated AmB, dramatically increased power production normalized to cathode area from both acetate (Acetate: from 0.9 to 3.1 W/m 2-cat) and wastewater (WW: 0.3 to 1.7 W/m2), by reducing solution and charge transfer resistances at the cathode. A second RED cell pair increased RED stack potential and reduced anode charge transfer resistance, further increasing power production (Acetate: 4.2 W/m2; WW: 1.9 W/m2). By maintaining near optimal electrode power production with fewer membranes, power densities normalized to total membrane ...
Hemoglobin or hemolysate is used as an indicator for leakage detection in the dialysis membrane interface separating the sterile from the nonsterile circuitry in a recirculating peritoneal dialysis system. The indicator is dissolved in the steril dialysis fluid and is retained within the sterile circuit unless leakage occurs in the membrane. Upon rupture or other leakage in the membrane, fluid turbulance and pressure gradient cause crossflow between the sterile and nonsterile circuitry, endangering the patient with infection, peritonitis and endotoxin shock. Such crossflow is detected by the concurrent coloration caused by the mixing of hemoglobin indicator in the nosterile dialysis fluid.
Treatment of oil and gas (O&G) wastewater is a growing practice that increases water resources available for beneficial reuse. Electrodialysis (ED) is an established desalination process with the potential to remove ions from saline produced water (PW), a byproduct of O&G production. However, the current ED literature lacks studies that investigate the fate of organic contaminants during ED treatment using real PW. This work examines ion exchange membrane (IEM) fouling, system performance, and the transport of organic constituents through IEMs during ED treatment of real PW. A bench-scale ED ...
Erythrocytes, Red Blood Cells (RBCs), have been utilized as biocompatible bioreactors and drug delivery vehicles. RBCs are also used as biological carriers for drugs, enzymes, and peptides. Hypo-osmotic dialysis technique is the most commonly employed to achieve drug encapsulation in RBCs with an appropriate yield. However, the use of RBCs as carriers for fluorescence labeled sensors has not been exploited. We have been investigating the feasibility of utilizing RBCs as optical carriers for biosensors. The first step is to ensure proper encapsulation and signal capture of the fluorescent probes. Streptavidin labeled with Alexa Fluor 750 (SA-AF 750) was utilized as the probe which was then loaded into the RBCs via the hypo-osmotic dialysis technique. The loaded cells were then scanned by using a spectrometer. The excitation scan was set at 750nm. The results showed a peak signal at 775 nm which was an indication of presence of AF 750 in the RBCs. This model could be used in future work to design in vivo
0008]One embodiment is a dialysis system. The dialysis system includes a dialyzer having dialysis fluid inlet and outlet ports, a blood pump connected to the dialyzer for pumping blood from a patient, at least one drip chamber in series with the dialyzer, a first multi-position valve for connection between the patient and the blood pump, and a second multi-position valve for connection between the patient and the drip chamber, wherein the first valve and the second valve are capable of connection in a first position for the first valve to allow a flow of blood from the patient to the blood pump and the second valve to allow a flow of the blood from the drip chamber to the patient, and are capable of connection in a second position for the second valve to allow a flow of blood from the patient to the blood pump and the first valve to allow a flow of the blood from the drip chamber to the patient. The dialysis system also includes a source of fresh dialysis fluid in series with the dialysis fluid ...
Providing practical, immediately useful guidelines that can be applied directly to patient care, Handbook of Dialysis Therapy is a must-have resource for all dialysis caregivers. This new edition has been updated with the latest cutting-edge technology, dialysis techniques, and complications related to various diseases for both pediatric and adult patients. In-depth yet concise, it explains complex dialysis concepts through abundant diagrams, photos, line drawings, and tables, while its readable hands-on approach allows for quick review of key information.. ...
Spectrum™ Spectra/Por™ 1 RC Dialysis Membrane Tubing 6000 to 8000 Dalton MWCO Flat width: 10mm Spectrum™ Spectra/Por™ 1 RC Dialysis Membrane...
[126 Pages Report] Check for Discount on Global Dialysis Membranes Sales Market Report 2021 report by QYResearch Group. The global Dialysis Membranes market is segmented by company, region (...
Our products fumasep FAB, FKB and FBM are designed and optimized for electrodialysis with bipolar membranes. The EDBM is the combination of conventional electrodialysis for salt separation with electrochemical water splitting for the conversion of a salt into its corresponding acid and base. fumasep FAB is an anion exchange membrane which is developed for very low proton crossover to receive a high concentration of acid. fumasep FKB is a cation exchange membrane optimized for high cation transport in combination with high OH- retention. fumasep FBM is a bipolar membrane, which induce the splitting of water into protons and hydroxide ions. The bipolar membrane fumasep FBM combines high selectivity and efficiency as well as high chemical stability within a broad pH range, excellent mechanical stability and low electrical resistance. It is ideally suited for the production of acid and base from the corresponding salts, as well as for innovative concepts such as biological fuel cells. The patented ...
Using One-Way ANOVA test and linear regression methods, the TAFO defined hydration status, but not the FO/ECW, kept a significant relationship with LAVI (p=0.03). When including age, sex, ethiology, dialysis vintage, comorbidities, dialysis technique, hypertension, biochemical parameters (Hemoglobin, Na, K, Albumin, Creatinin), and all echocardiographic measurements including valvular regurgitation and left ventricle mass index, the only confounding factors identified were lean and fat mass percentages related to total weight, and diastolic function measured by transmitral velocities ratio, but the adjusted relationship kept significant (p=0.036).. Plasma sodium was not different between the 37 patients with (136.6mEq/l; CI 95% 135.8-137.4) and 35 patients without (137.3mEq/l; IC95% 136.1-138.6) atrial dilatation (p=0.314).. Left ventricle hypertrophy was present in 73.7% of patients and concentric remodeling in 7.9%. Concentric hypertrophy was present in 63.2% of patients and eccentric ...
Reports, articles and other documents harvested from the Office of Scientific and Technical Information.. Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.. ...
Profile: Electrodialysis Units, Electro-Membrane Processes, Wastewater Treatment, Crude Glycerol Treatment, Bipolar Electrodialysis
A sucrose solution containing red-colored methyl red indicator at a pH of 4.5 is added to a semi-permeable dialysis membrane bag. The membrane bag is immersed in a solution of pH 7.0. The solution inside the membrane becomes yellow as the pH is raised due to the flow of pH 7.0 solution into the dialysis membrane. The column also rises as this change occurs.. The pressure exerted by the column forces some of the solution in the dialysis membrane bag out of the bottom of the dialysis bag. The presence of this yellow solution is observed by adding acid to the beaker to change the yellow methyl red to the more intense red color.. ...
5. During the dialysis, if the patient suffered from an abdominal pain, the doctor should adjust the position of dialysis tubing or regulate the temperature, flow rate, pH value of dialysate. Taking hot pack or gentle massage to deal with abdominal distension. Additionally, eating more food rich in cellulose should be encouraged. Taking certain medications if necessary ...
Shop a large selection of General Dialysis Supplies products and learn more about Spectrum Spectra/Por 1-4 Standard RC Dialysis Membrane in Flat Sheets:Life Spectra/Por 2
Ready-to-use dialysis system for quick and efficient dialysis and buffer exchange for small up to large volumes. The tube has the dialysis membrane pre-installed and is easily opened and closed with a screw cap. No struggling with closures and leaking knots or risking puncturing the membrane. Delivered with a flotation ring for improved buoyancy and vertical orientation.. ...
Shop a large selection of products and learn more about Spectrum™ Spectra/Por™ 4 RC Dialysis Membrane Tubing 12,000 to 14,000 Dalton MWCO .
In article ,6pltqb$kua$1 at,, murphy_r at (Roger Murphy) wrote: , Ian, , , In the past Ive used dialysis tubing to concentrate proteins by merely , hanging them in an air stream - like in a fume hood and leave the motor , running. I guess this is a variation on what youre thinking of. It worked , quite nicely (volume reduction of ~80%), but be careful of precipitation , problems of either your protein or salts if you caary it too far. , , Hope this helps, , , Roger or alternatively, you can use aquacide (a highly hygroscopic powder) and place your bag in it. Works quite nicely, Peter ...
When you experience total renal (kidney) failure, your kidneys can no longer perform their usual task of filtering waste from your bloodstream. Dialysis artificially replaces your kidneys by hooking you up to a mechanism that performs kidney functions for you. A dialysis system helps to control blood pressure; removes waste, salt and extra water from your body; and maintains a safe level of bloodstream chemicals like sodium, potassium and bicarbonate. Dialysis can be performed in a hospital, in a separate dialysis unit, or at home with the proper equipment.
A blood purification system comprised of a dialysis system for purifying a patients blood and a dual-lumen catheter coupled to the dialysis system. The dual-lumen catheter is comprised of an elongated cylindrical tube having an internal diametral septum extending along the length thereof. The septum and the walls of the elongated cylindrical tube form at least three longitudinal lumens, the first and second of which have substantially semi-circular transverse cross-sections occupying the major portion of the transverse cross section of the interior of the tube, and the third lumen has a small transverse cross-section located at the intersection of one diametral end of the septum with the tube, between a pair of adjacent corners of the first and second lumens.
A medical fluid machine includes: an enclosure; at least one medical fluid delivery component located inside the enclosure, the component capable of being powered by an external power source or a back-up battery; a transistor in electrical communication with the battery; and a regulator configured to: (i) receive as feedback a supply voltage; and (ii) vary a gate voltage at the transistor to maintain the supply voltage at least substantially at a desired level.
DNA may stick to dialysis tubing after current flow. Either reverse the electrodes and run for 15 seconds to dislodge the DNA or be careful to resuspend the DNA before removing the buffer. To resuspend DNA inside the tubing, first open one clip and carefully remove the agarose slice (which can be restained to verify elution) without losing any buffer. Then replace the clip and with your fingers, press along the length of tubing to mix the DNA with the buffer. Open the clip and remove the buffer with a pipetman. If low yields are suspected, add another 100 l 1 X buffer to the empty tubing and repeat these steps to rinse out the tubing. Final volume should be less than 600 l. If the agarose slice is much longer than 4 cm, the amount of buffer retrieved may be much more than 600 l. In this case split the DNA buffer into two or three tubes so that no tube has more than 600 l ...
Outsets technology, the Tablo™ Hemodialysis System, is the first novel dialysis system to reach the U.S. market in more than 15 years. The system can be used flexibly across a range of clinical settings from dialysis clinics to hospitals and skilled nursing facilities. The company will use proceeds from the financing to expand the commercial introduction of the Tablo System in acute and chronic care markets in the United States ...
TY - JOUR. T1 - The diagnostic accuracy of brain microdialysis during surgery: a qualitative systematic review. AU - Bossers, S.M.. AU - de Boer, R.D.H.. AU - Boer, C.. AU - Peerdeman, S.M.. PY - 2013. Y1 - 2013. U2 - 10.1007/s00701-012-1582-z. DO - 10.1007/s00701-012-1582-z. M3 - Article. C2 - 23275069. VL - 155. SP - 345. EP - 353. JO - Acta Neurochirurgica. JF - Acta Neurochirurgica. SN - 0001-6268. IS - 2. ER - ...
Registered Nurses (RNs) care for people who are sick, injured, convalescent or disabled. Under general supervision, they deliver care to patients utilizing the nursing process of assessment, planning, intervention, implementation, and evaluation, in accordance with established philosophy. RNs collaborate with other professional disciplines to ensure effective patient care delivery and achievement of desired patient outcomes. RNs effectively interact with patient and significant others, while maintaining the standard of professional nursing. The nature of the direction and supervision required for this position varies by State and job setting. Dialysis Nurses provide care and support for patients suffering from acute and chronic renal (kidney) failure. They assist pre- and during dialysis procedures, following physician orders ...
Registered Nurses (RNs) care for people who are sick, injured, convalescent or disabled. Under general supervision, they deliver care to patients utilizing the nursing process of assessment, planning, intervention, implementation, and evaluation, in accordance with established philosophy. RNs collaborate with other professional disciplines to ensure effective patient care delivery and achievement of desired patient outcomes. RNs effectively interact with patient and significant others, while maintaining the standard of professional nursing. The nature of the direction and supervision required for this position varies by State and job setting. Dialysis Nurses provide care and support for patients suffering from acute and chronic renal (kidney) failure. They assist pre- and during dialysis procedures, following physician orders ...
The technique of microdialysis enables sampling and collecting of small‐molecular‐weight substances from the interstitial space
71 High Cut Off Microdialysis Bolt Catheter - unique new brain Microdialysis catheter with High cut off membrane for bolt implantation ...

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