Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Diabetes Mellitus
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Diabetes Complications
Diabetes Mellitus, Experimental
Diabetes, Gestational
Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Hemoglobin A, Glycosylated
Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.
Risk Factors
Glucose Tolerance Test
Diabetic Nephropathies
KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
Diabetic Neuropathies
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
Insulin Resistance
Diabetic Retinopathy
Prevalence
Obesity
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Islets of Langerhans
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Pregnancy in Diabetics
Streptozocin
Diabetic Ketoacidosis
Body Mass Index
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
Hypertension
Prediabetic State
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Glucose Intolerance
A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
Prospective Studies
Hypoglycemia
Follow-Up Studies
Cardiovascular Diseases
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Insulin-Secreting Cells
Diabetes Insipidus
A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
Glucose
Metformin
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Incidence
Blood Glucose Self-Monitoring
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
C-Peptide
The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
Treatment Outcome
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Glutamate Decarboxylase
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.
Cross-Sectional Studies
Risk Assessment
Diabetic Diet
Comorbidity
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Pregnancy
Mice, Inbred NOD
Metabolic Syndrome X
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Multivariate Analysis
Rats, Inbred BB
Thiazolidinediones
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Reference Values
Insulin Infusion Systems
Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.
Body Weight
Fructosamine
Logistic Models
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Lipids
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Dipeptidyl-Peptidase IV Inhibitors
Coronary Artery Disease
Diabetic Foot
Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
Odds Ratio
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Genetic Predisposition to Disease
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Pancreas
A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
Dyslipidemias
Glucagon-Like Peptide 1
A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Proportional Hazards Models
Glycosuria
Self Care
Asian Continental Ancestry Group
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Autoantibodies
Glucose Clamp Technique
Chi-Square Distribution
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Life Style
Genotype
Islet Amyloid Polypeptide
A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Questionnaires
Indians, North American
Disease Progression
Coronary Disease
Islets of Langerhans Transplantation
Risk
Disease Management
A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)
Proinsulin
A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts.
Analysis of Variance
Glucagon
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
Wolfram Syndrome
A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.
Sex Distribution
Disease Models, Animal
Severity of Illness Index
Adiponectin
A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the white ADIPOSE TISSUE. Adiponectin modulates several physiological processes, such as metabolism of GLUCOSE and FATTY ACIDS, and immune responses. Decreased plasma adiponectin levels are associated with INSULIN RESISTANCE; TYPE 2 DIABETES MELLITUS; OBESITY; and ATHEROSCLEROSIS.
Incretins
Oxidative Stress
Glomerular Filtration Rate
Venoms
Prognosis
Hyperinsulinism
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
Cholesterol, HDL
Age Distribution
Myocardial Infarction
Cholesterol
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Atherosclerosis
Diabetes Mellitus, Lipoatrophic
Polymorphism, Single Nucleotide
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Age of Onset
Cholesterol, LDL
HLA-DQ Antigens
Polymorphism, Genetic
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
Glycosylation End Products, Advanced
Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.
Longitudinal Studies
Diabetic Cardiomyopathies
Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.
Endocrinology
Drug Therapy, Combination
Rats, Zucker
Confidence Intervals
Exercise
Linear Models
Glycemic Index
Rats, Wistar
Kidney
Rats, Inbred OLETF
Hypolipidemic Agents
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Mass Screening
Registries
Double-Blind Method
C-Reactive Protein
Alleles
Endothelium, Vascular
Liver
African Continental Ancestry Group
Autonomic Nervous System Diseases
Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION.
Fetal Macrosomia
A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.
Aging
Transcription Factor 7-Like 2 Protein
Adipose Tissue
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
Metabolic Diseases
Autoimmunity
Rats, Sprague-Dawley
Randomized Controlled Trials as Topic
Health Surveys
Malaysia
A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)
Autoimmune Diseases
Gene Frequency
Hypercholesterolemia
Gastroparesis
Homeostasis
Leptin
Primary Health Care
Practice Guidelines as Topic
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Lipid Metabolism
Insulin, Long-Acting
Netherlands
Pilot Projects
Receptor-Like Protein Tyrosine Phosphatases, Class 8
Fatty Acids, Nonesterified
Renal Dialysis
Obesity, Morbid
Protein Tyrosine Phosphatase, Non-Receptor Type 1
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Chlorpropamide
Sodium-Glucose Transporter 2
Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus. (1/10340)
Previously we demonstrated the expression of the long form of the leptin receptor in rodent pancreatic beta-cells and an inhibition of insulin secretion by leptin via activation of ATP-sensitive potassium channels. Here we examine pancreatic islets isolated from pancreata of human donors for their responses to leptin. The presence of leptin receptors on islet beta-cells was demonstrated by double fluorescence confocal microscopy after binding of a fluorescent derivative of human leptin (Cy3-leptin). Leptin (6.25 nM) suppressed insulin secretion of normal islets by 20% at 5.6 mM glucose. Intracellular calcium responses to 16.7 mM glucose were rapidly reduced by leptin. Proinsulin messenger ribonucleic acid expression in islets was inhibited by leptin at 11.1 mM, but not at 5.6 mM glucose. Leptin also reduced proinsulin messenger ribonucleic acid levels that were increased in islets by treatment with 10 nM glucagon-like peptide-1 in the presence of either 5.6 or 11.1 mM glucose. These findings demonstrate direct suppressive effects of leptin on insulin-producing beta-cells in human islets at the levels of both stimulus-secretion coupling and gene expression. The findings also further indicate the existence of an adipoinsular axis in humans in which insulin stimulates leptin production in adipocytes and leptin inhibits the production of insulin in beta-cells. We suggest that dysregulation of the adipoinsular axis in obese individuals due to defective leptin reception by beta-cells may result in chronic hyperinsulinemia and may contribute to the pathogenesis of adipogenic diabetes. (+info)Obstructive uropathy and hydronephrosis in male KK-Ay mice: a report of cases. (2/10340)
Uropathy associated with hydronephrosis was observed frequently in our male KK-Ay mouse colony during a long-term study of diabetes. The lesion occurred in 24 of the 31 KK-Ay male mice and accounted for the greatest number of spontaneous deaths among them. It was observed after 4 months of age and involved about hard plugs of altered seminal material resembling the seminal vesicle secretion. The plugs became impacted in the urethral bulb and the bladder. The penile anatomy, with its flexure, pressure on the urethra from the bulbocavernosus muscle, and the characteristic ability of the seminal fluid to easily coagulate to form the vaginal plug may have contributed to the lesion. Correlation between development of the uropathy and diabetes has not been established. (+info)Role of glutamine in human carbohydrate metabolism in kidney and other tissues. (3/10340)
Glutamine is the most abundant amino acid in the human body and is involved in more metabolic processes than any other amino acid. Until recently, the understanding of many aspects of glutamine metabolism was based on animal and in vitro data. However, recent studies using isotopic and balance techniques have greatly advanced the understanding of glutamine metabolism in humans and its role in glucose metabolism in the kidney and other tissues. There is now evidence that in postabsorptive humans, glutamine is an important glucose precursor and makes a significant contribution to the addition of new carbon to the glucose carbon pool. The importance of alanine for gluconeogenesis, viewed in terms of the addition of new carbons, is less than previously assumed. It appears that glutamine is predominantly a renal gluconeogenic substrate, whereas alanine gluconeogenesis is essentially confined to the liver. As shown recently, renal gluconeogenesis contributes 20 to 25% to whole-body glucose production. Moreover, glutamine has been shown not only to stimulate net muscle glycogen storage but also to stimulate gluconeogenesis in normal humans. Finally, in humans with type II diabetes, conversion of glutamine to glucose is increased (more so than that of alanine). The available evidence on the hormonal regulation of glutamine gluconeogenesis in kidney and liver and its alterations under pathological conditions are discussed. (+info)Prevalence of hepatitis B surface antigen and antibody in white and black patients with diabetes mellitus. (4/10340)
The prevalence of hepatitis B surface antigen (HBSAg) and antibody (anti-HBS) was determined in 531 white and 519 black diabetic outpatients and in appropriate white and black control populations. There was no difference between the prevalence of either HBSAg or anti-HBS in either the white or black diabetics and that in the white and black controls. These findings make it unlikely that the vast majority of patients with diabetes mellitus have either an increased susceptibility to infection by the hepatitis B virus or an impaired ability to clear the virus once they are infected. (+info)An audit of the care of diabetics in a group practice. (5/10340)
The diabetics in a general practice of 20,175 patients were identified during one year and 119 were found-a prevalence of 5.9 per thousand.The age and sex distribution, method of treatment, criteria of diabetic control, complications, and present method of care were analysed from the medical records to examine the process of medical care of a chronic disease in general practice. (+info)Regulation of fatty acid homeostasis in cells: novel role of leptin. (6/10340)
It is proposed that an important function of leptin is to confine the storage of triglycerides (TG) to the adipocytes, while limiting TG storage in nonadipocytes, thus protecting them from lipotoxicity. The fact that TG content in nonadipocytes normally remains within a narrow range, while that of adipocytes varies enormously with food intake, is consistent with a system of TG homeostasis in normal nonadipocytes. The facts that when leptin receptors are dysfunctional, TG content in nonadipocytes such as islets can increase 100-fold, and that constitutively expressed ectopic hyperleptinemia depletes TG, suggest that leptin controls the homeostatic system for intracellular TG. The fact that the function and viability of nonadipocytes is compromised when their TG content rises above or falls below the normal range suggests that normal homeostasis of their intracellular TG is critical for optimal function and to prevent lipoapoptosis. Thus far, lipotoxic diabetes of fa/fa Zucker diabetic fatty rats is the only proven lipodegenerative disease, but the possibility of lipotoxic disease of skeletal and/or cardiac muscle may require investigation, as does the possible influence of the intracellular TG content on autoimmune and neoplastic processes. (+info)Reversing adipocyte differentiation: implications for treatment of obesity. (7/10340)
Conventional treatment of obesity reduces fat in mature adipocytes but leaves them with lipogenic enzymes capable of rapid resynthesis of fat, a likely factor in treatment failure. Adenovirus-induced hyperleptinemia in normal rats results in rapid nonketotic fat loss that persists after hyperleptinemia disappears, whereas pair-fed controls regain their weight in 2 weeks. We report here that the hyperleptinemia depletes adipocyte fat while profoundly down-regulating lipogenic enzymes and their transcription factor, peroxisome proliferator-activated receptor (PPAR)gamma in epididymal fat; enzymes of fatty acid oxidation and their transcription factor, PPARalpha, normally low in adipocytes, are up-regulated, as are uncoupling proteins 1 and 2. This transformation of adipocytes from cells that store triglycerides to fatty acid-oxidizing cells is accompanied by loss of the adipocyte markers, adipocyte fatty acid-binding protein 2, tumor necrosis factor alpha, and leptin, and by the appearance of the preadipocyte marker Pref-1. These findings suggest a strategy for the treatment of obesity by alteration of the adipocyte phenotype. (+info)Screening of Korean forest plants for rat lens aldose reductase inhibition. (8/10340)
Naturally occurring substances which can prevent and treat diabetic complications were sought by examining ethanol extracts prepared from Korean forest plants for their inhibitory effects on rat lens aldose reductase activity in vitro. Among the plants examined, Acer ginnala, Illicium religiosum and Cornus macrophylla exerted the most strong inhibitory activity on aldose reductase. (+info)
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Diabetes Mellitus and Bitter Melon
HLA A1-B8-DR3-DQ2
In insulin dependent diabetes mellitus[edit]. In type 1 diabetes both DR3 and DQ2 appear to play a role. DR3-DQ2.5 can be ... DQ2 that are possessed by other haplotypes also confer susceptibility to type 1 diabetes. Type 1 diabetes has a risk associated ... Juvenile diabetes, Sarcoidosis B8::DQ2 Autoimmune hepatitis, Primary biliary cirrhosis, Myasthenia gravis, Dermatitis ... In addition the BAT1 and MICB variant is more common in type 1 diabetes when B8 is absent but DR3 is present[10] These studies ...
Sucrose
Diabetes mellitus[edit]. Diabetes mellitus, a disease that causes the body to metabolize sugar poorly, occurs when either: *the ... What I need to know about Eating and Diabetes Archived 2011-05-11 at the Wayback Machine.. Diabetes.niddk.nih.gov. Retrieved on ... such as persons with hypoglycemia or diabetes mellitus. Sucrose can contribute to the development of metabolic syndrome.[43] In ... the body's cells exhibit impaired responses to insulin (Type 2 diabetes).. When glucose builds up in the bloodstream, it can ...
Diabetes mellitus
... ≥11.1 (≥200). ≥7.0 (≥126). ≥48. ≥6.5 Diabetes mellitus is characterized by recurrent or persistent high ... Main article: Diabetes mellitus type 1. Type 1 diabetes mellitus is characterized by loss of the insulin-producing beta cells ... Diabetes mellitus cases due to a known defect are classified separately. Type 2 DM is the most common type of diabetes mellitus ... See also: Prevention of diabetes mellitus type 2. There is no known preventive measure for type 1 diabetes.[2] Type 2 diabetes ...
Branched-chain amino acid
Role in diabetes mellitus type 2[edit]. In addition to cell signaling, the mTOR pathway also plays a role in beta cell growth ... "World Journal of Diabetes. 3 (3): 38-53. doi:10.4239/WJD.v3.i3.38. PMC 3310004. PMID 22442749.. ... Blood levels of the BCAAs are elevated in obese, insulin resistant humans and in mouse and rat models of diet-induced diabetes ... suggesting the possibility that BCAAs contribute to the pathogenesis of obesity and diabetes.[10][11] BCAA-restricted diets ...
List of Guidances for Statistics in Regulatory Affairs
Diabetes mellitus[edit]. *FDA: Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes[38] ... for the treatment of diabetes mellitus. Specifically, this guidance makes recommendations about how to demonstrate that a new ... FDA - Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes ... antidiabetic therapy to treat type 2 diabetes is not associated with an unacceptable increase in cardiovascular risk. ...
Paternal age effect
Diabetes mellitus[edit]. High paternal age has been suggested as a risk factor for type 1 diabetes,[25] but research findings ... Textbook of Diabetes. John Wiley & Sons. p. 39.. CS1 maint: Uses authors parameter (link) CS1 maint: Uses editors parameter ( ... Bishop DB, O'Connor PJ, Desai J (2010). "Diabetes". Chronic Disease Epidemiology and Control (3rd ed.). Washington, DC: ... Stene LC, Harjutsalo V, Moltchanova E, Tuomilehto J (2011). "Epidemiology of Type 1 Diabetes". In Holt RIG, Cockram C, ...
Intercurrent disease in pregnancy
Diabetes mellitus[edit]. Main article: Diabetes mellitus and pregnancy. Diabetes mellitus and pregnancy deals with the ... interactions of diabetes mellitus (not restricted to gestational diabetes) and pregnancy. Risks for the child include ...
Beta blocker
Diabetes mellitus[edit]. Beta-blockers can exacerbate hypoglycemia by interfering with glycogenesis and can mask signs of ... Blood glucose level monitoring is necessary in a patient with diabetes mellitus. ... 2007 study revealed diuretics and beta blockers used for hypertension increase a patient's risk of developing diabetes mellitus ... Elliott WJ, Meyer PM (January 2007). "Incident diabetes in clinical trials of antihypertensive drugs: a network meta-analysis ...
Diabetic nephropathy
The process may be initially indolent, making regular screening for DN in patients with diabetes mellitus of great importance.[ ... Diabetic nephropathy affects approximately a third of patients with type 1 and type 2 diabetes mellitus. DN is responsible for ... Cardiovascular risk reduction: Patients with diabetes mellitus are at significantly increased risk of cardiovascular disease, ... Diabetic nephropathy in type 2 diabetes can be more difficult to predict because the onset of diabetes is not usually well ...
Placental disease
Diabetes mellitus. *Maternal age less than 20 years or over the age of 35 ... Risk factors such as diabetes, chronic blood pressure and multiple pregnancies can increase the risk of developing placental ...
Pituitary apoplexy
Oxford Textbook of Endocrinology and Diabetes. Oxford: Oxford University Press. pp. 161-2. ISBN 978-0-19-263045-2.. ... Jane JA Jr; Vance ML; Laws ER (2006). "Neurogenic diabetes insipidus". Pituitary. 9 (4): 327-9. doi:10.1007/s11102-006-0414-7. ... Finally, 10-25% develop diabetes insipidus, the inability to retain fluid in the kidneys due to a lack of the pituitary ... Diabetes mellitus. *types: *type 1. *type 2. *gestational. *MODY 1 2 3 4 5 6 ...
Primordial dwarfism
Diabetes mellitus. *types: *type 1. *type 2. *gestational. *MODY 1 2 3 4 5 6 ...
Graves' disease
Diabetes mellitus type 1. *Hashimoto's thyroiditis. *Multiple sclerosis. *Coeliac disease. *Giant-cell arteritis ... Those with other autoimmune diseases such as type 1 diabetes and rheumatoid arthritis are more likely to be affected.[1] ...
Endocrine disease
Diabetes mellitus. *types: *type 1. *type 2. *gestational. *MODY 1 2 3 4 5 6 ...
Diabetic neuropathy
... refers to various types of nerve damage associated with diabetes mellitus. Symptoms depend on the site of ... The Diabetes Control and Complications Trial Research Group. (1995). "The effect of intensive diabetes therapy on the ... A systematic review of randomized trials to prevent the occurrence of plantar foot ulcers in patients with diabetes". Diabetes ... "Diabetes. 57 (6): 1446-1454. doi:10.2337/db08-0057. PMID 18511445. Archived from the original on 2009-04-15.. ...
Graves' disease
Diabetes mellitus type 1. *Hashimoto's thyroiditis. *Multiple sclerosis. *Coeliac disease. *Giant-cell arteritis ... Experimental and Clinical Endocrinology and Diabetes. 112 (4): 171-174. doi:10.1055/s-2004-817930. PMID 15127319.. ... Those with other autoimmune diseases such as type 1 diabetes and rheumatoid arthritis are more likely to be affected.[1] ...
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Diabetes mellitus. *types: *type 1. *type 2. *gestational. *MODY 1 2 3 4 5 6 ...
Delayed puberty
Diabetes mellitus. *types: *type 1. *type 2. *gestational. *MODY 1 2 3 4 5 6 ...
Diabetic nephropathy
... is the chronic loss of kidney function occurring in those with diabetes mellitus. It is a serious complication, affecting ... Diabetic nephropathy in type 2 diabetes can be more difficult to predict because the onset of diabetes is not usually well ... beginning immediately after a diagnosis of type 2 diabetes and five years after a diagnosis of type 1 diabetes.[16][18] ... "Journal of Diabetes Investigation. 2 (4): 243-247. ISSN 2040-1116. PMC 4014960 . PMID 24843491. doi:10.1111/j.2040-1124.2011. ...
Microalbuminuria
2000). "Evolution of incipient nephropathy in type 2 diabetes mellitus". Kidney Int. 58 (3): 1228-37. doi:10.1046/j.1523- ... "Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study ... Microalbuminura in diabetes *^ a b Person-microalbumin level (measured) at Australian Institute of Health and Welfare. 01/03/ ... and macroalbuminuria in pregnant woman with type 1 diabetes". Diabetes Care. 29 (4): 924-925. doi:10.2337/diacare.29.04.06.dc06 ...
Manos Hadjidakis - Wikipédia, a enciclopédia livre
diabetes mellitus Página oficial http://www.manoshadjidakis.com Assinatura [edite no Wikidata] ...
James Baskett - Wikipédia, a enciclopédia livre
diabetes mellitus [edite no Wikidata]. James Baskett (Indianápolis, 16 de fevereiro de 1904 - Los Angeles, 9 de julho de 1948) ...
Alexander Graham Bell - Wikipédia, a enciclopédia livre
Diabetes mellitus Assinatura Alexander Graham Bell (signature).svg Alexander Graham Bell (Edimburgo, 3 de março de 1847 - Beinn ...
Human leukocyte antigen
Diabetes mellitus type 1. 6[4]. HLA-DR3 and. -DR4 combined. Diabetes mellitus type 1. 15[4]. ... People with certain HLA antigens are more likely to develop certain autoimmune diseases, such as type I diabetes, ankylosing ... type I diabetes, coeliac disease). HLA may also be related to people's perception of the odor of other people, and may be ... HLA typing has led to some improvement and acceleration in the diagnosis of celiac disease and type 1 diabetes; however, for ...
Novartis
Diabetes mellitus type 2. 910. 2012[83]. 39%. Gilenya (fingolimod). Multiple sclerosis. 1,195. 2012[83]. 142%. ... and the diabetes drug, Starlix.[120] Twenty-seven states, the District of Columbia and Chicago and New York also joined.[119] ...
Linkage disequilibrium
Diabetes mellitus type 1 DR4 6 75 30 0.64 In Table 4, some examples of association between HLA alleles and diseases are ... values, among other diseases, juvenile diabetes mellitus (type 1) has a strong association with DR4 even with a low relative ...
Polyphagia
... in diabetes[edit]. Diabetes mellitus causes a disruption in the body's ability to transfer glucose from food into ... Polyphagia is one of the most common symptoms of diabetes mellitus. It is associated with hyperthyroidism and endocrine ... Healthline.com article "What are the 3 Ps of Diabetes?" *^ MACDONALD CRITCHLEY, PERIODIC HYPERSOMNIA AND MEGAPHAGIA IN ... "Hypothalamic melanocortin signaling and leptin resistance--perspective of therapeutic application for obesity-diabetes ...
Silver-Russell syndrome
Transient neonatal diabetes mellitus. Retrieved from "https://en.wikipedia.org/w/index.php?title=Silver-Russell_syndrome&oldid= ...
Antioxidant
Davì G, Falco A, Patrono C (2005). "Lipid peroxidation in diabetes mellitus". Antioxidants & Redox Signaling. 7 (1-2): 256-68. ... Giugliano D, Ceriello A, Paolisso G (March 1996). "Oxidative stress and diabetic vascular complications". Diabetes Care. 19 (3 ... the pathologies caused by diabetes,[162][163] rheumatoid arthritis,[164] and neurodegeneration in motor neuron diseases.[165] ...
Mitochondrial disease
Diabetes mellitus and deafness (DAD) *this combination at an early age can be due to mitochondrial disease ... Diabetes 54, 2005 1926-33 *^ a b Mitchell, Peter. "David Keilin's respiratory chain concept and its chemiosmotic consequences" ... Lorini & Ciman, M, & M (1962). "Hypoglycaemic action of Diisopropylammonium salts in experimental diabetes". Institute of ... explored the role of mitochondria in insulin resistance among the offspring of patients with type 2 diabetes.[12] Other studies ...
Type 2 diabetes
... Other names. Diabetes mellitus type 2;. adult-onset diabetes;[1]. noninsulin-dependent diabetes mellitus ( ... "Monogenic Forms of Diabetes: Neonatal Diabetes Mellitus and Maturity-onset Diabetes of the Young". National Diabetes ... American Diabetes Association (January 2010). "Diagnosis and classification of diabetes mellitus". Diabetes Care. 33 Suppl 1 ( ... American Diabetes Association (January 2012). "Diagnosis and classification of diabetes mellitus". Diabetes Care. 35 Suppl 1 ( ...
Ketone
... usually due to diabetes mellitus). Although ketoacidosis is characteristic of decompensated or untreated type 1 diabetes, ... ketosis or even ketoacidosis can occur in type 2 diabetes in some circumstances as well. ...
Quantitative trait locus
... discusses how simple polygenic inheritance cannot explain some diseases such as the onset of Type I diabetes mellitus, and that ... Many disorders with genetic components are polygenic, including autism, cancer, diabetes and numerous others. Most phenotypic ...
Cushing's disease
diabetes mellitus[8]. *erectile dysfunction. DiagnosisEdit. Diagnosis is made first by diagnosing Cushing's syndrome, which can ... Diabetes insipidus (15%), fluid and electrolyte abnormalities (12.5%), and neurological deficits (5.6%) were the most common ...
Rituximab
... type 1 diabetes mellitus, Sjogren's syndrome, anti-NMDA receptor encephalitis and Devic's disease,[23] Graves' ophthalmopathy,[ ...
Hematopoietic stem cell transplantation
... following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus". ... diabetes in children and adults. Results have been promising; however, as of 2009[update] it was premature to speculate whether ... these experiments will lead to effective treatments for diabetes.[19] Allogeneic[edit]. Allogeneic HSCT involves two people: ...
Diabetes mellitus tip II
Njihet edhe si diabet që nuk varet nga insulina (angl: non insulin dependent diabetes mellitus). ... b. Studimi i quajtur DCCT (Diabetes control and complications trial) tregoi se është e rëndësishme që niveli i hemoglobinës të ... Marrë nga "https://sq.wikipedia.org/w/index.php?title=Diabetes_mellitus_tip_II&oldid=1606571" ...
Medical device
Diagnostic Medical Equipment may also be used in the home for certain purposes, e.g. for the control of diabetes mellitus ...
Pulmonya, ang malayang ensiklopedya
Ang wastong paggamot ng nasa ilalim na mga karamdaman (tulad ng HIV/AIDS, diabetes mellitus, at malnutrisyon) ay maaaring ...
Dieting
Elliott Proctor Joslin (2005). Joslin's Diabetes Mellitus: Edited by C. Ronald Kahn ... [et Al.]. Lippincott Williams & Wilkins ... 1994). "Effects of varying carbohydrate content of diet in patients with non-insulin-dependent diabetes mellitus". JAMA. 271 ( ... basing this recommendation on Matthew Dobson's discovery of glycosuria in diabetes mellitus.[11] By means of Dobson's testing ... "Diabetes Care. 31 (Suppl 1): S61-78. doi:10.2337/dc08-S061. PMID 18165339.. ...
Wikipedia:Makala za msingi za kamusi elezo/Zote 1000, kamusi elezo huru
Diabetes mellitus * sw:Diabetes mellitus. Dialectic * sw:Dialectic. Diamond * sw:Diamond. Dictatorship * sw:Dictatorship. Diego ...
ادرار کردن - ویکیپدیا، دانشنامهٔ آزاد
Polyuria, abnormally large production of urine, associated with, in particular, diabetes mellitus (types 1 and 2), and diabetes ...
കൺജങ്റ്റൈവ - വിക്കിപീഡിയ
Ditzel, Jørn (1967-01-12). "The in Vivo Reactions of the Small Blood Vessels to Diabetes Mellitus". Acta Medica Scandinavica ( ... Isenberg, S. J.; McRee, W. E.; Jedrzynski, M. S. (1986-10-01). "Conjunctival hypoxia in diabetes mellitus". Investigative ... "Microvascular abnormalities in the bulbar conjunctiva of patients with type 2 diabetes mellitus". Endocrine Practice. 7 (5): ... "Quantitative morphometry of conjunctival microcirculation in diabetes mellitus". Microvascular Research. 18 (2): 153-166. doi: ...
糖尿病 - 維基百科,自由的百科全書
糖尿病(拉丁語:diabetes mellitus,縮寫為DMs,簡稱diabetes)是一種代謝性疾病,它的特徵是患者的血糖長期高於標準值[7]。高血糖會造成俗稱「三多一少」的症狀:多食(英語:polyphagia)、多飲(英語:polydipsia) ... International Diabetes Federation: Diabetes Atlas. [4 April 2014].. *^ IDF DIABETES ATLAS (PDF) 6. International Diabetes ... Latest diabetes figures paint grim global picture. *^ RSSDI textbook of diabetes mellitus. Rev. 2nd ed
Diabetic ketoacidosis - Simple English Wikipedia, the free encyclopedia
... is a medical emergency that can happen in people with diabetes mellitus. DKA happens mostly in people with Type 1 diabetes, ... DKA can also be a sign that a person has diabetes that has not been discovered, or is not being controlled well. ... although it may happen in some people that have Type 2 diabetes. ...
Momordica charantia
Ooi, C. P.; Yassin, Z; Hamid, T. A. (2012). "Momordica charantia for type 2 diabetes mellitus". The Cochrane Library. 8 (8): ... With regard to the use of Momordica charantia for diabetes, several animal studies and small-scale human studies have ... Momordica charantia has a number of purported uses including cancer prevention, treatment of diabetes, fever, HIV and AIDS, and ... Momordica charantia may be beneficial in diabetes; however, the effects seem to depend on how it is consumed.[14] More studies ...
多囊卵巢綜合症 - 维基百科,自由的百
Legro RS, Kunselman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired ... Diabetes Care. 2011-10-01, 34 (10): 2329-2330 [2015-05-24]. ISSN 0149-5992. PMC 3177745. PMID 21949224. doi:10.2337/dc11-1153. ... Diabetes & Metabolic Syndrome (Review). 2017. PMID 28416368. doi:10.1016/j.dsx.2017.03.030.. ... 2-Hour oral glucose tolerance test (GTT) in women with risk factors (obesity, family history, history of gestational diabetes)[ ...
Diabetes mellitus
... (DM), commonly referred tae as diabetes, is a group o metabolic diseases in which thare are heich bluid ... "Diabetes Blue Circle Symbol". International Diabetes Federation. 17 March 2006. Archived frae the oreeginal on 5 August 2007.. ... "Management of blood glucose in type 2 diabetes mellitus" (PDF). American Family Physician. 79 (1): 29-36. PMID 19145963. ... "Diabetes Fact sheet N°312". WHO. October 2013. Archived frae the oreeginal on 26 August 2013. Retrieved 25 March 2014.. ...
Fruit and vegetables for kids
A 2007 study by Boeing et al., explored common chronic lifestyle diseases including diabetes type 2 mellitus, obesity, ... proposed a decrease in weight gain as a result of increased consumption lessens the risk of developing diabetes type 2 mellitus ...
Diuretic
However, in certain conditions, such as diabetes mellitus, the concentration of glucose in the blood (hyperglycemia) exceeds ... glucose (especially in uncontrolled diabetes), mannitol Promotes osmotic diuresis 2. proximal tubule, descending limb ...
நீரிழிவு நோய் (இரண்டாவது வகை) - தமிழ் விக்கிப்பீடியா
"Monogenic Forms of Diabetes: Neonatal Diabetes Mellitus and Maturity-onset Diabetes of the Young". National Diabetes ... "J Diabetes Sci Technol 3 (4): 722-6. பப்மெட்:20144319. *↑ 24.0 24.1 "Screening: Type 2 Diabetes Mellitus in Adults". U.S. ... 49.0 49.1 49.2 49.3 49.4 49.5 49.6 49.7 49.8 editor, Leonid Poretsky, (2009). Principles of diabetes mellitus (2nd ). New York ... Diabetes mellitus type 1), கர்ப்பகால நீரிழிவு (gestational diabetes) கொண்டவர்களாகவும் உள்ளனர். இந்நோய் உருவாவதற்கு, மரபியல் ...
Index of HIV/AIDS-related articles
... diabetes mellitus (DM) - diagnosis - diarrhea - diplopia - dissemination - division of acquired immunodeficiency syndrome ( ...
Momordica charantia
"Momordica charantia for type 2 diabetes mellitus" (PDF). The Cochrane Library. 8 (8): CD007845. doi:10.1002/14651858.CD007845. ... With regard to the use of Momordica charantia for diabetes, several animal studies and small-scale human studies have ... Momordica charantia has a number of purported uses including cancer prevention, treatment of diabetes, fever, HIV and AIDS, and ... Momordica charantia may be beneficial in diabetes; however, the effects seem to depend on how it is consumed.[14] More studies ...
Familial amyloid polyneuropathy
AIAPP/Diabetes mellitus type 2. Retrieved from "https://en.wikipedia.org/w/index.php?title=Familial_amyloid_polyneuropathy& ...
Chronic obstructive pulmonary disease
... diabetes mellitus, muscle wasting, osteoporosis, lung cancer, anxiety disorder, sexual dysfunction, and depression.[2][39] In ...
"கனடாவின் முதல் குடிமக்கள்" பக்கத்தின் திருத்தங்களுக்கிடையேயான வேறுபாடு - தமிழ்...
Epidemiology of diabetes mellitus among First Nations and non-First Nations adults ,journal=Canadian Medical Association ... main,First Nations and diabetes}}. There are marked differences between the epidemiology of diabetes in First Nation population ... Reasons for the different rate of [[Type 2 diabetes,Type 2 Diabetes]] between First Nation and the general population include a ... Age-standardized rates show that the prevalence of diabetes among First Nations individuals living on-reserve is 17.2%; First ...
Isotretinoin
Diabetes mellitus. *Hyperuricaemia. Psychiatric *Depression. *Aggravated depression. *Aggressive tendencies. *Anxiety. *Mood ...
Corneal ulcer
In all corneal ulcers it is important to rule out predisposing factors like diabetes mellitus and immunodeficiency. ...
Urinary tract infection
... and the person has diabetes mellitus, is pregnant, is male, or immunocompromised, it is considered complicated.[6][17] ... Some also support treatment of those with diabetes mellitus[78] and treatment before urinary tract procedures which will likely ... Female anatomy, sexual intercourse, diabetes, obesity, family history[2]. Diagnostic method. Based on symptoms, urine culture[3 ... Other risk factors include diabetes,[4] being uncircumcised,[37][38] and having a large prostate.[9] In children UTIs are ...
Diabetes mellitus - Wikipedia
Diabetes mellitus. ≥11.1 (≥200). ≥7.0 (≥126). ≥48. ≥6.5 Diabetes mellitus is characterized by recurrent or persistent high ... Main article: Diabetes mellitus type 1. Type 1 diabetes mellitus is characterized by loss of the insulin-producing beta cells ... Diabetes mellitus cases due to a known defect are classified separately. Type 2 DM is the most common type of diabetes mellitus ... See also: Prevention of diabetes mellitus type 2. There is no known preventive measure for type 1 diabetes.[2] Type 2 diabetes ...
Diabetes mellitus
2. Diabetes * 3. Diabetes Um milhão de portugueses entre os 20 e os 79 anos de idade possui Diabetes. A Diabetes Tipo 1 ... Diabetes mellitus * 1. Diabetes Mellitus Ana Morgado, CS Marinha Grande * ... 7. O que é a Diabetes? * 8. O que é a Diabetes? A HIPERGLICÉMIA característica da diabetes pode ser causada por: Produção ... O termo diabetes mellitus descreve uma desordem metabólica de etiologia múltipla, caracterizada por uma hiperglicemia crónica ...
Definition: Diabetes Mellitus
... sugar diabetes) is a condition that occurs when the body cant use glucose (a type of sugar) normally. ... Diabetes mellitus. Diabetes Mellitus. Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the ... In diabetes, the pancreas does not make enough insulin (type 1 diabetes) or the body cant respond normally to the insulin that ... is made (type 2 diabetes). This causes glucose levels in the blood to rise, leading to symptoms such as increased urination, ...
Diabetes Mellitus: MedlinePlus
Diabetes mellitus type 1 - Wikipedia
7.5% of diabetes cases[8]. Diabetes mellitus type 1, also known as type 1 diabetes, is a form of diabetes mellitus in which ... Diabetes mellitus. ≥11.1 (≥200). ≥7.0 (≥126). ≥48. ≥6.5 Diabetes mellitus is characterized by recurrent or persistent ... "Diabetes Mellitus (DM): Diabetes Mellitus and Disorders of Carbohydrate Metabolism: Merck Manual Professional". Merck.com. ... Further information: Complications of diabetes mellitus. Complications of poorly managed type 1 diabetes mellitus may include ...
Diabetes Mellitus Tipo 2
DIABETES MELLITUS Es un síndrome metabólico consistente en hiperglucemia, glucosuria, polifagia, polidipsia, poliuria y ... Diabetes Mellitus Tipo 2 * 1. DIABETES MELLITUS ,ul,,li,Es un síndrome metabólico consistente en hiperglucemia, glucosuria, ... li,,/ul,DIABETES MELLITUS TIPO 2 * 10. ,ul,,li,La obesidad, la falta de actividad física, embarazo, infecciones graves o el ... li,,/ul,DIABETES MELLITUS TIPO 2 * 11. FACTORES QUE SE RELACIONAN ,ul,,li,A ntecedentes hereditarios ,/li,,/ul,,ul,,li,O ...
Diabetes mellitus
Noel Christopher Diabetes Mellitus Type 2 cure
... will show you how to change your life style and beat type 2 diabetes mellitus. Helping to understand Diabetes Mellitus and what ... and find a cure for diabetes! using the internet. ... the medical world do not tell you .... Diabetes sufferers are ... World Health Organization Over 300 million world wide have diabetesWhat is diabetes?Diabetes is a chronic disease that occurs ... Sugar and Diabetes The Deliberate Use of Refined Sugar to Assist Degenerative Disease like diabetes.Read about diabetes and ...
Word! Diabetes Mellitus (for Kids) - Nemours
... sugar diabetes. When someone has diabetes, his or her body doesnt use glucose properly. ... Diabetes mellitus is sometimes called "sugar diabetes." When someone has diabetes, his or her body doesnt use glucose properly ... type 1 diabetes) or the body cant respond normally to the insulin that is made (type 2 diabetes). If diabetes is not under ... In diabetes, the pancreas does not make enough insulin ( ... Diabetes Mellitus. (En español:Diabetes mellitus). Say: dye-uh- ...
Permanent neonatal diabetes mellitus: MedlinePlus Genetics
Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists ... medlineplus.gov/genetics/condition/permanent-neonatal-diabetes-mellitus/ Permanent neonatal diabetes mellitus. ... Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists ... Permanent neonatal diabetes mellitus--the importance of diabetes differential diagnosis in neonates and infants. Eur J Clin ...
diabetes mellitus | American Academy of Pediatrics
Genetic and Epigenetic Factors in Etiology of Diabetes Mellitus Type 1 Karmen Stankov, Damir Benc, Dragan Draskovic ... Ethnic Differences in Mortality From Insulin-Dependent Diabetes Mellitus Among People Less Than 25 Years of Age Rebecca Lipton ... Fatal Malignant Hyperthermia-Like Syndrome With Rhabdomyolysis Complicating the Presentation of Diabetes Mellitus in Adolescent ... Bariatric Surgery for Severe Obesity in Two Adolescents With Type 1 Diabetes Janet Chuang, Meg H. Zeller, Thomas Inge, Nancy ...
Diagnosis and Classification of Diabetes Mellitus
... was developed by the National Diabetes Data Group (NDDG) and published in 1979 ... The current classification and diagnosis of diabetes used in the U.S. ... Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. ... The current classification and diagnosis of diabetes used in the U.S. was developed by the National Diabetes Data Group (NDDG) ...
Vitamin D and diabetes mellitus | SpringerLink
... the incidence of type-1 and possibly also of type-2 diabetes mellitus and may improve the metabolic control in the diabetes ... 2 diabetes. Both these conditions are associated with inflammation and type-1 diabetes also with an autoimmune pathology. ... F.B. Hu, J.B. Meigs, T.Y. Li, N. Rifai, J.E. Manson, Diabetes 53, 693-700 (2004)PubMedCrossRefGoogle Scholar ... A.G. Pittas, S.S. Harris, P.C. Stark, B. Dawson-Hughes, Diabetes Care 30, 980-986 (2007)PubMedCrossRefGoogle Scholar ...
Diabetes Mellitus in Cats
Diabetes mellitus (DM) affects between 0.2 - 1% of cats in the general population. DM is a condition of high blood sugar ( ... 6, 2019 /CNW/ - Diabetes mellitus (DM) affects between 0.2 - 1% of cats in the general population. DM is a condition of high ... How is Diabetes treated in cats?. The main treatment of DM is insulin. Your veterinary team will teach you how to inject the ... Diabetes is diagnosed by the presence of clinical signs as well as high glucose concentrations in the blood and urine. If your ...
Diabetes Mellitus, the diabetic diet and health complications
Informaton on fasting as a diabetic, teenage diabetes, and the connection between uranium and diabetes. ... Health care articles on diabetes and diabetes-related health complications. ... Diabetes Mellitus Information. The Diabetic Diet and Complications. Home > Search > Privacy > Contact > Health Articles need ... Teenage Diabetes There has been a truly alarming increase in teens diagnosed with diabetes in the past few years. I believe, as ...
Decreased stature in gestational diabetes mellitus | SpringerLink
... diabetes mellitus and 109 with pre-existing Type I (insulin-dependent) diabetes mellitus were included in the study. There was ... We chose to examine body stature in women with gestational diabetes mellitus (GDM), a prediabetic state affecting a young group ... Type II diabetes 158.2 ± 7.0 (p , 0.001, analysis of variance]. Height in Type I diabetes (160.1 ± 5.9) did not differ from the ... Keywords Diabetes gestational stature insulin resistance body mass index socio-economic factors. ...
Diabetes mellitus in Saudi Arabia. - PubMed - NCBI
Diabetes mellitus in Saudi Arabia.. Al-Nozha MM1, Al-Maatouq MA, Al-Mazrou YY, Al-Harthi SS, Arafah MR, Khalil MZ, Khan NB, Al- ... Diabetes mellitus (DM) is a major public health problem worldwide, and it is a known risk factor for coronary artery disease ( ... Diabetes mellitus was more prevalent among Saudis living in urban areas of 25.5% compared to rural Saudis of 19.5% (p,0.00001 ... The data were analyzed to classify individuals as diabetic, impaired fasting glucose and normal, using 1997 American Diabetes ...
Principles of Diabetes Mellitus | Leonid Poretsky | Springer
The past few years have witnessed major developments in our understanding of diabetes and in therapeutic approaches to this ... Principles of Diabetes Mellitus. Editors. * Leonid Poretsky Copyright. 2017. Publisher. Springer International Publishing. ... Revises and expands on classic earlier editions, providing a comprehensive text on diabetes mellitus ... Provides a global perspective on diabetes mellitus, diabetic syndromes and related disorders ...
Pregnancy Complicated by Diabetes Mellitus | The BMJ
Diabetes Mellitus and Pernicious Anaemia | The BMJ
Mitochondrial diabetes mellitus: a review
An A to G transversion mutation in the tRNA(Leu(UUR)) gene is associated with diabetes in about 1.5% of the dia … ... DNA mutations and the prevalence as well as the pathobiochemical and clinical features of mitochondrial diabetes mellitus. ... Mitochondrial diabetes mellitus: a review Biochim Biophys Acta. 1995 May 24;1271(1):253-60. doi: 10.1016/0925-4439(95)00036-4. ... An A to G transversion mutation in the tRNA(Leu(UUR)) gene is associated with diabetes in about 1.5% of the diabetic population ...
Diabetes Mellitus Type 1 Inheritance
Type 1 diabetes is an inherited condition and individuals with a first degree relative who has the condition are at an ... Diabetes Mellitus Type 1 Inheritance. News-Medical. 21 September 2019. ,https://www.news-medical.net/health/Diabetes-Mellitus- ... Diabetes Mellitus Type 1 Inheritance. News-Medical. https://www.news-medical.net/health/Diabetes-Mellitus-Type-1-Inheritance. ... Diabetes Mellitus Type 1 Inheritance. News-Medical, viewed 21 September 2019, https://www.news-medical.net/health/Diabetes- ...
Diabetes mellitus - Wikiversity
Diabetes mellitus is characterized by chronic hyperglycemia (see below). There are many forms of diabetes (Pre-diabetes, Type 1 ... Type I diabetes. External links[edit]. *Gunness, S., Bholah, R., Ackbarkhan, A. (2008). Educating Diabetes patients and youth ... Diabetes mellitus refers to a number of diseases that have in common elevated blood sugar levels. ... Diabetes mellitus is also treated with insulin sensitizing pills and/or injections with exogenous insulin. When managing ...
Calaméo - Diabetes Mellitus
diabetes mellitus | Hypertension
Hypertension and Diabetes MellitusCoprediction and Time Trajectories Vasilis Tsimihodimos, Clicerio Gonzalez-Villalpando, James ... Do We Need a Patient-Centered Target for Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes Mellitus?Novelty ... Hypertension Control in Adults With Diabetes Mellitus and Recurrent Cardiovascular EventsNovelty and SignificanceGlobal Results ... Abstract P533: Distinct Molecular Compositions of Circulating Microparticles in Hypertension and Diabetes Maddison Turner, Jean ...
Pathogenesis of type 2 diabetes mellitus. - PubMed - NCBI
Pathogenesis of type 2 diabetes mellitus.. Leahy JL1.. Author information. 1. University of Vermont College of Medicine, ... Whether the diabetes phenotype will occur depends on many environmental factors that share an ability to stress the glucose ... The pathological sequence for type 2 diabetes is complex and entails many different elements that act in concert to cause that ... This sequence also provides insight into how to better prevent or treat type 2 diabetes, by studying the molecular basis for ...
Non-insulin-dependent diabetes mellitus | medical disorder | Britannica
The sulfonylureas are oral hypoglycemic agents used as adjuncts to diet and exercise in the treatment of type 2 diabetes. ... Other articles where Non-insulin-dependent diabetes mellitus is discussed: therapeutics: Hormones: …are also available for ... maturity-onset diabetes, type 2 diabetes, type 2 diabetes mellitus, type II diabetes, type II diabetes mellitus ... In diabetes mellitus: Type 2 diabetes mellitus. Type 2 diabetes is far more common than type 1 diabetes, accounting for about ...
Stress and Diabetes Mellitus | Diabetes Care
2018 by the American Diabetes Association. Diabetes Care Print ISSN: 0149-5992, Online ISSN: 1935-5548. ... Your Name) has forwarded a page to you from Diabetes Care Message Body (Your Name) thought you would like to see this page from ... Although human studies on the role of stress in the onset and course of type II diabetes are few, a large body of animal study ... Although this is of adaptive importance in a healthy organism, in diabetes, as a result of the relative or absolute lack of ...
Type 1 Diabetes Mellitus Differential Diagnoses
Type 1 diabetes is a chronic illness characterized by the bodys inability to produce insulin due to the autoimmune destruction ... encoded search term (Type 1 Diabetes Mellitus) and Type 1 Diabetes Mellitus What to Read Next on Medscape ... Type 2 Diabetes Mellitus * Fast Five Quiz: How Well Do You Know the Risk Factors and Treatment Indications for Type 2 Diabetes ... Aathira R, Jain V. Advances in management of type 1 diabetes mellitus. World J Diabetes. 2014 Oct 15. 5 (5):689-96. [Medline]. ...
Diabetic Mastopathy: Complication of Diabetes Mellitus
... is a breast-related complication of type 1 or type 2 insulin-dependent diabetes mellitus (IDDM). It manifests as hard, fibrous ... DMP has been found to be more common in type I diabetes mellitus than in type II diabetes mellitus. Some studies report that ... Diabetic mastopathy (DMP) is a breast-related complication of type 1 or type 2 insulin-dependent diabetes mellitus (IDDM). It ... New diagnostic approach to evaluate the skin complications of diabetes mellitus. *Timing of physical activity associated with ...
GestationalHyperglycemiaNIDDMManagement of type 1 diabetPancreasAdult-onset diInsulin ResistanceIDDMPrevalence of diabetesType of diabetesTypes of diabetes mellitusMaturity-onset diabetesObesityClinicalSymptomsPatientsDiagnosis of diabetesTIPOSearchChronic diseaseScreeningEtiologyMetabolic disorderComplications of diabeAutoimmuneHttpsPathogenesis of diabetesPregnancyGlycemic ControlBlood glucose levelsPathophysiology2017MedlinePlusEndocrineTreatmentCommonlyNutrition1992Diabetic dietJuvenile diabetesHypoglycemiaDiseasesMetabolismIncidence of TypeNeonatalAffectsIncreased urinationPreventionOccursDietForms of diabetes2019RiskInsulina2001
Gestational49
- Gestational diabetes is the third main form, and occurs when pregnant women without a previous history of diabetes develop high blood sugar levels. (wikipedia.org)
- [11] Gestational diabetes usually resolves after the birth of the baby. (wikipedia.org)
- Gestational diabetes mellitus. (nih.gov)
- Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. (nih.gov)
- The aim of this document is to define and describe diabetes as we know it today, present a classification scheme that reflects its etiology and/or pathogenesis, provide guidelines for the diagnosis of the disease, develop recommendations for testing that can help reduce the morbidity and mortality associated with diabetes, and review the diagnosis of gestational diabetes. (medscape.com)
- We chose to examine body stature in women with gestational diabetes mellitus (GDM), a prediabetic state affecting a young group of people. (springer.com)
- Keywords Diabetes gestational stature insulin resistance body mass index socio-economic factors. (springer.com)
- Diabetes mellitus is categorized as Type 1, Type 2 and gestational, depending on how the absorption is disrupted. (reference.com)
- Gestational Diabetes - You develop this at the time of your pregnancy. (medindia.net)
- Gestational diabetes mellitus (GDM) is a condition in which a hormone made by the placenta prevents the body from using insulin effectively. (hopkinsmedicine.org)
- Unlike type 1 diabetes, gestational diabetes is not caused by a lack of insulin, but by other hormones produced during pregnancy that can make insulin less effective, a condition referred to as insulin resistance. (hopkinsmedicine.org)
- Approximately 3 to 8 percent of all pregnant women in the United States are diagnosed with gestational diabetes. (hopkinsmedicine.org)
- Normally, the pancreas is able to make additional insulin to overcome insulin resistance, but when the production of insulin is not enough to overcome the effect of the placental hormones, gestational diabetes results. (hopkinsmedicine.org)
- What are the risks factors associated with gestational diabetes mellitus? (hopkinsmedicine.org)
- How is gestational diabetes mellitus diagnosed? (hopkinsmedicine.org)
- Treatment for gestational diabetes focuses on keeping blood glucose levels in the normal range. (hopkinsmedicine.org)
- Unlike type 1 diabetes, gestational diabetes generally occurs too late to cause birth defects. (hopkinsmedicine.org)
- Women with gestational diabetes mellitus generally have normal blood sugar levels during the critical first trimester. (hopkinsmedicine.org)
- Cross sectional examination of 26 patients with type 1 diabetes, 75 patients with type 2 diabetes and 17 patients with gestational diabetes. (scielo.cl)
- No skin lesion was found in patients with gestational diabetes. (scielo.cl)
- Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with first recognition during pregnancy. (health.am)
- Gestational diabetes mellitus: influence of race on disease prevalence. (washington.edu)
- Gestational diabetes: Antepartum characteristics that predict postpartum glucose intolerance and type 2 diabetes in Latino women. (washington.edu)
- Predicting future diabetes mellitus in Latino women with gestational diabetes. (washington.edu)
- Long-term diabetogenic effect of single pregnancy in women with previous gestational diabetes mellitus. (washington.edu)
- Contraception and the risk of type 2 diabetes mellitus in Latino women with prior gestational diabetes mellitus. (washington.edu)
- Gestational diabetes mellitus (position statement). (washington.edu)
- Comparison of glyburide and insulin in women with gestational diabetes mellitus. (washington.edu)
- There are different types of diabetes we encounter nowadays, but the three main types are Type I, Type II and gestational diabetes (Diabetes Mellitus,2005-2016). (bartleby.com)
- Although gestational diabetes disappears after birth, women with GDM are at increased risk for developing diabetes later in life. (bartleby.com)
- Search terms Gestational Diabetes Mellitus, Physical activity, Nutrition, Pregnancy, Management Literature review Clinical trial by Morisset et al. (bartleby.com)
- Gestational diabetes is a glucose intolerance that develops during pregnancy. (bartleby.com)
- Early diagnosis and effective treatment are important because gestational diabetes can cause serious maternal and fetal complications. (bartleby.com)
- Diet and exercise are the first line treatment options of gestational diabetes, while insulin therapy is the first line medical treatment option. (bartleby.com)
- Nurses' play an important role in education and support of gestational diabetes because they provide day-to-day care for their patients. (bartleby.com)
- 1). Gestational diabetes mellitus is just one of the many types of diabetes Aboriginal people are faced with. (bartleby.com)
- Gestational Diabetes Mellitus Screening Description of Gestational Diabetes Mellitus Gestational diabetes mellitus (GDM) is a form of diabetes that occurs in pregnant women who do not have a prior history of diabetes mellitus (American Diabetes Association, 2016). (bartleby.com)
- Complications from Gestational Diabetes Gestational diabetes, glucose intolerance with onset or first recognition occurring during pregnancy, is a problem more pregnant women are facing. (bartleby.com)
- The exact prevalence rate of gestational diabetes mellitus is unknown but in the United States it is estimated to affect anywhere from one to 14 percent of pregnancies (Desisto, Shin, & Sharma, 2014). (bartleby.com)
- There are several risk factors which increase a woman's risk for gestational diabetes. (bartleby.com)
- gestational diabetes (O24.4-) neonatal diabetes mellitus (P70.2) postpancreatectomy diabetes mellitus (E13. (aapc.com)
- [6] Type 2 diabetes makes up about 90% of cases of diabetes , with the other 10% due primarily to diabetes mellitus type 1 and gestational diabetes . (wikipedia.org)
- Other forms of diabetes include gestational diabetes (pregnancy diabetes), diabetes after operative resection of the pancreas, and rare forms of genetic diabetes. (scienceinschool.org)
- Gestational diabetes mellitus (GDM) is a type of diabetes (high blood sugar) that occurs in pregnant women. (clinicaltrials.gov)
- The association of milder forms of gestational diabetes with adverse pregnancy outcomes, including morbidities such as macrosomia, birth trauma, and neonatal hypoglycemia, remains questionable. (clinicaltrials.gov)
- Free Preview Lecture 'Gestational Diabetes Mellitus: Theory of Reasoned Action' Online Course on Udemy. (teachertube.com)
- Discount Coupon: https://www.udemy.com/gestational-diabetes-mellitus-theory-of-reasoned-action/?couponCode=GESTATIONALDIABETES What you'll learn Theory of Reasoned Action, Identification of Pre-Diabetes and Diagnosis of Diabetes, Impaired fasting glucose (IFG) and Impaired glucose tolerance (IGT), Pregestational Diabetes, Screening and Diagnosis through Pregnancy, Macrosomia Story, Developing Medicinal Adherence: Continuous Glucose Observation, Protocols of Insulin administration, Twice daily regime and Four times daily regime, and Oral Hypoglycaemic agents. (teachertube.com)
- The American College of Obstetricians and Gynecologists (ACOG) recommends that all women with gestational diabetes be tested for diabetes at the 6-week postpartum visit and at regular intervals thereafter. (cdc.gov)
- To capture better data, the Utah Office of Vital Records and Statistics modified the data entry program for birth certificates to collect maternal self-report of gestational diabetes and added an edit to the system that will flag the clerk if the gestational diabetes fields are in conflict. (cdc.gov)
Hyperglycemia16
- Diabetes mellitus is a group of autoimmune diseases characterized by defects in insulin secretion resulting in hyperglycemia (an abnormally high concentration of glucose in the blood). (norml.org)
- This form of diabetes is characterized by high blood sugar levels (hyperglycemia) resulting from a shortage of the hormone insulin. (medlineplus.gov)
- Diabetes mellitus is characterized by chronic hyperglycemia (see below). (wikiversity.org)
- Stress is a potential contributor to chronic hyperglycemia in diabetes. (diabetesjournals.org)
- Human studies have shown that stress can stimulate hyperglycemia, hypoglycemia, or have no affect at all on glycemic status in established diabetes. (diabetesjournals.org)
- Although human studies on the role of stress in the onset and course of type II diabetes are few, a large body of animal study supports the notion that stress reliably produces hyperglycemia in this form of the disease. (diabetesjournals.org)
- In the past few years, new drugs have been developed that exploit glucose loss in the urine as a means to counteract hyperglycemia in diabetes. (washington.edu)
- Diabetes mellitus is well known as a chronic metabolic disease that is characterized by a relative or absolute lack of insulin, resulting in hyperglycemia. (hindawi.com)
- Type 2 diabetes mellitus is characterized by hyperglycemia, insulin resistance, and relative impairment in insulin secretion. (uptodate.com)
- Diabetes mellitus, a clinical syndrome characterized by deficiency of or insensitivity to insulin and exposure of organs to chronic hyperglycemia, is the most common medical complication of pregnancy. (health.am)
- Which type 1 diabetes mellitus (DM) comorbidities may aggravate hyperglycemia? (medscape.com)
- See 'Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes mellitus' and 'Management of blood glucose in adults with type 1 diabetes mellitus' and 'Initial management of blood glucose in adults with type 2 diabetes mellitus' and 'Management of persistent hyperglycemia in type 2 diabetes mellitus' . (uptodate.com)
- Introduction: Type 2 Diabetes Mellitus is characterized either by beta cell failure resulting in inadequate production of the hormone insulin (which is responsible for the uptake of glucose in body cells from the blood), or insulin resistance leading to decreased tissue sensitivity or response to insulin, resulting in hyperglycemia (Mahan, Escott-Stump & Raymond, 2012). (bartleby.com)
- 9 , 10 Insulin resistance, which is usually present before the onset of diabetes, is determined by a number of factors, including genetics, age, obesity and, later in the disease, hyperglycemia itself. (cmaj.ca)
- 11 The inability to suppress hepatic glucose production is a major contributor to the fasting hyperglycemia seen in diabetes. (cmaj.ca)
- An increase in hepatic gluconeogenesis is believed to be an important factor responsible for the fasting hyperglycemia detected in patients with non-insulin-dependent diabetes mellitus (NIDDM). (pnas.org)
NIDDM2
- The two major forms of diabetes are type 1 (previously called insulin-dependent diabetes mellitus (IDDM) or juvenile-onset diabetes) and type 2 (previously called non insulin-dependent diabetes mellitus (NIDDM) or maturity-onset diabetes). (medindia.net)
- Elderly persons who have non-insulin-dependent diabetes mellitus (NIDDM) and other symptomatic medical conditions may also have a higher risk of developing psychological problems. (cdc.gov)
Management of type 1 diabet1
- Aathira R, Jain V. Advances in management of type 1 diabetes mellitus. (medscape.com)
Pancreas13
- Diabetes is due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced. (wikipedia.org)
- In diabetes, the pancreas does not make enough insulin ( type 1 diabetes ) or the body can't respond normally to the insulin that is made ( type 2 diabetes ). (kidshealth.org)
- Diabetes mellitus type 1 , also known as type 1 diabetes , is a form of diabetes mellitus in which very little or no insulin is produced by the pancreas . (wikipedia.org)
- Diabetes mellitus - often referred to simply as diabetes - is a condition in which the body either does not produce enough, or does not properly respond to, insulin , a hormone produced in the pancreas . (wikimedia.org)
- A small number of individuals with permanent neonatal diabetes mellitus have an underdeveloped pancreas. (medlineplus.gov)
- Type 1 diabetes is caused by the malfunction of the pancreas, which fails to produce insulin, explains WebMD. (reference.com)
- The pancreas of those with Type 2 diabetes does produce insulin, but either it is not produced in enough quantity, or the insulin produced is ineffective in helping the body absorb glucose. (reference.com)
- This may be due to autoimmune destruction of the insulin-secreting cells of the pancreas ( type 1 diabetes mellitus ) or it may result from a problem in the responsiveness of tissues to insulin, known as insulin resitance ( type 2 diabetes mellitus ). (washington.edu)
- Strikingly, the missense p.Ser64Phe MAFA mutation was associated with either of two distinct phenotypes, multiple insulin-producing neuroendocrine tumors of the pancreas-a condition known as insulinomatosis-or diabetes mellitus, recapitulating the physiological properties of MAFA both as an oncogene and as a key islet β-cell transcription factor. (pnas.org)
- We investigated a large pedigree with autosomal dominant inheritance of diabetes mellitus or insulinomatosis, an adult-onset condition of recurrent hyperinsulinemic hypoglycemia caused by multiple insulin-secreting neuroendocrine tumors of the pancreas. (pnas.org)
- Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces or both (WHO definition). (bartleby.com)
- Type 2 diabetes is a metabolic disorder that results from complex interactions of multiple factors and is characterized by 2 major defects: decreased secretion of insulin by the pancreas and resistance to the action of insulin in various tissues (muscle, liver and adipose), which results in impaired glucose uptake. (cmaj.ca)
- [1] In diabetes mellitus type 1 there is a lower total level of insulin to control blood glucose, due to an autoimmune induced loss of insulin-producing beta cells in the pancreas . (wikipedia.org)
Adult-onset di5
- Individuals diagnosed with type 2 diabetes (also known as adult onset diabetes) produce inadequate amounts of insulin. (norml.org)
- Authors concluded, "Based on these data, it can be suggested that THCV may be useful for the treatment of the metabolic syndrome and/or type 2 diabetes (adult onset diabetes), either alone or in combination with existing treatments. (norml.org)
- They reported that past and present cannabis consumers possessed a lower prevalence of adult onset diabetes, even after authors adjusted for social variables (ethnicity, level of physical activity, etc.), despite all groups possessing a similar family history of diabetes. (norml.org)
- Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes. (womenshealthmag.com)
- VA presumes a service-connected relationship exists, based on the eligibility criteria below, that diabetes mellitus (Type II), or adult-onset diabetes, is associated with exposure to Agent Orange. (va.gov)
Insulin Resistance8
- Better understanding of the physiological role of the vitamin-D system, in particular its potential effects on inflammatory and autoimmune conditions as well as on insulin secretion and possibly also on insulin resistance, increased the interest in its potential role in prevention and control of the diabetic condition, both type-1 and -2 diabetes. (springer.com)
- Type 2 diabetes (T2D) is associated with insulin resistance and a lack of adequate compensation by the beta cells which lead to a relative insulin deficiency [ 7 ]. (hindawi.com)
- Obesity is very common in type 2 diabetes and contributes greatly to insulin resistance. (health.am)
- Use of the Estimated Glucose Disposal Rate (eGDR) as a Measure of Insulin Resistance in an Urban Multiethnic Population With Type 1 Diabetes. (medscape.com)
- Diabetes is one of the major chronic diseases caused by the insulin resistance that body generates within. (bartleby.com)
- Diabetes mellitus type 2 (also known as type 2 diabetes ) is a long-term metabolic disorder that is characterized by high blood sugar , insulin resistance , and relative lack of insulin . (wikipedia.org)
- The vast majority of patients with Type 2 diabetes or pre-diabetes are characterised by insulin resistance. (scienceinschool.org)
- Type 1 diabetes is commonly caused by the body's failure to produce insulin, while type 2 diabetes usually results from body not being able to respond to the insulin, a condition called insulin resistance. (snpedia.com)
IDDM4
- Diabetic mastopathy (DMP) is a breast-related complication of type 1 or type 2 insulin-dependent diabetes mellitus (IDDM). (news-medical.net)
- We overviewed the pathophysiological features of diabetes in relation to its complications in type 1 and type 2 mice along with rat models, including Zucker Diabetic Fatty (ZDF) rats, BB rats, LEW 1AR1/-iddm rats, Goto-Kakizaki rats, chemically induced diabetic models, and Nonobese Diabetic mouse, and Akita mice model. (hindawi.com)
- Insulin dependent diabetes mellitus (IDDM), commonly referred to as Type 1 diabetes, is an auto-immune disease that affects the islets of Langerhans, destroying the body's ability to produce insulin. (google.com)
- Young people with insulin- dependent diabetes mellitus (IDDM) may have a higher prevalence of eating disorders, such as anorexia nervosa and bulimia, and adults with longstanding diabetes and major medical complications have a higher prevalence of symptoms of depression and anxiety. (cdc.gov)
Prevalence of diabetes13
- The prevalence of diabetes has reached epidemic proportions world wide. (google.com)
- While the global prevalence of diabetes is 6.4% , the prevalence varies from 10.2% in the Western Pacific to 3.8% in the African region. (google.com)
- Among adults in the United States, the estimated overall prevalence of diabetes ranges from 12 to 14 percent, depending on the criteria used [ 2 ]. (uptodate.com)
- Other national databases, such as the National Health and Nutrition Examination Survey (NHANES), have reported an increase in the prevalence of diabetes over two decades (from 9.8 to 12.4 percent), but have confirmed the relatively stable (approximately 12 percent) prevalence between 2008 and 2012 [ 2,4 ]. (uptodate.com)
- Given the marked increase in childhood obesity, there is concern that the prevalence of diabetes will continue to increase substantially. (uptodate.com)
- The prevalence of diabetes is higher in certain populations. (uptodate.com)
- Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. (washington.edu)
- age-adjusted prevalence of diabetes is 3 to 5 times higher in First Nations than in the general population" (Introduction section, para. (bartleby.com)
- 4 It has been suggested that the increased expenditure was due to both the increasing prevalence of diabetes and the increased use of insulin analogues. (cmaj.ca)
- In the USA, where the prevalence of diabetes is high, it is estimated that one in three people will develop Type 2 diabetes. (scienceinschool.org)
- In Egypt, the prevalence of diabetes is about 8% and this level is increasing over time. (prezi.com)
- Insufficient data on the prevalence of diabetes make it difficult to target appropriate women for education and intervention. (cdc.gov)
- Comparing diabetes data taken from birth certificates with self-reported data from the PRAMS survey shows a wide variation in prevalence of diabetes. (cdc.gov)
Type of diabetes5
- Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists throughout the lifespan. (medlineplus.gov)
- Type 2 diabetes (formerly known as adult-onset or non-insulin-dependent diabetes) is the more common type of diabetes, constituting 90 to 95 percent of cases. (britannica.com)
- Distinguishing the type of diabetes can be difficult in (1) patients who are treated with insulin and who are younger but clinically appear to have type 2 DM and (2) older patients with late-onset diabetes who nonetheless take insulin and seem to share characteristics of patients with type 1 DM. (medscape.com)
- 6 The equations take into consideration risk factors such as age and hemoglobin A 1c levels, as well as patient characteristics, type of diabetes and history of diabetes-related complications. (cmaj.ca)
- Four families are described in which two or more members with this type of diabetes are present, and in each family, affected individuals share a haplotype including HL-A8 or W15. (diabetesjournals.org)
Types of diabetes mellitus1
- The two most common types of diabetes mellitus are type 1 diabetes (T1D) and type 2 diabetes (T2D). (hindawi.com)
Maturity-onset diabetes3
- A Prospective study of maturity-onset diabetes mellitus and risk of coronary artery disease and stroke in women. (washington.edu)
- Based on etiology, diabetes is classified as type 1 diabetes mellitus, type 2 diabetes mellitus, latent autoimmune diabetes, maturity-onset diabetes of youth, and miscellaneous causes. (aafp.org)
- Patients with maturity-onset diabetes of youth typically present before 25 years of age, have only impaired insulin secretion, and have a monogenetic defect that leads to an autosomal dominant inheritance pattern. (aafp.org)
Obesity10
- Obesity greatly increases the risk of diabetes. (womenshealthmag.com)
- Cite) Modifiable risk factors: The modifiable risk factors for diabetes mellitus are obesity, lack of physical activity, unhealthy eating habits and social and economic condition. (bartleby.com)
- 2 With the growing elderly Canadian population, the rising prevalence of obesity and the alarming increase in childhood and adolescent type 2 diabetes, the burden of this disease will continue to grow. (cmaj.ca)
- This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient. (routledge.com)
- Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. (nature.com)
- Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. (wikipedia.org)
- Rates of type 2 diabetes have increased markedly since 1960 in parallel with obesity. (wikipedia.org)
- Type 2 diabetes is mainly a disease of the elderly, but as rates of obesity increase, more and more young adults, and even adolescents, are being diagnosed with this form of the disease. (scienceinschool.org)
- Some forms of diabetes, such as T2D also have a strong environmental component - especially diet and obesity are risk factors for T2D. (snpedia.com)
- 6 With the rise in childhood obesity, type 2 diabetes is increasingly being diagnosed in children and adolescents. (aafp.org)
Clinical10
- About 12 percent of people with type 1 diabetes have clinical depression. (wikipedia.org)
- Diabetes is diagnosed by the presence of clinical signs as well as high glucose concentrations in the blood and urine. (newswire.ca)
- 1 Institutes of Clinical Chemistry and Diabetes Research, Academic Hospital Schwabing, Munich, Germany. (nih.gov)
- We review the relationship between various types of mitochondrial DNA mutations and the prevalence as well as the pathobiochemical and clinical features of mitochondrial diabetes mellitus. (nih.gov)
- For further information about the diagnosis and management of monogenic diabetes, the ADA suggests consulting the 2009 clinical practice consensus guidelines of the International Society for Pediatric and Adolescent Diabetes (ISPAD) at the ISPAD website . (medscape.com)
- Ensure that clinicians working within the context of diabetes mellitus are able to engage in fundamental processes of clinical decision making, critically reflexive practice and possess a critical awareness of the health and social care policy and governance processes underpinning diabetes mellitus provision within the context of healthcare. (diabetes.org.uk)
- See 'Pathogenesis of type 2 diabetes mellitus' and 'Clinical presentation and diagnosis of diabetes mellitus in adults' . (uptodate.com)
- This prospective randomized controlled multicenter clinical trial compared the effects of intensive insulin therapy aimed at achieving the near normalization of glycemia with the effects of conventional insulin therapy on the initiation and progression of complications in patients with type 1 diabetes. (health.am)
- Increased prevalence of clinical gallbladder disease in subjects with non-insulin-dependent diabetes mellitus. (washington.edu)
- Abnormal regulation of these substances may contribute to the clinical presentation of diabetes. (uptodate.com)
Symptoms11
- The classic symptoms of untreated diabetes are weight loss, polyuria (increased urination), polydipsia (increased thirst), and polyphagia (increased hunger). (wikipedia.org)
- Several other signs and symptoms can mark the onset of diabetes although they are not specific to the disease. (wikipedia.org)
- About 6 percent of people with type 1 diabetes have celiac disease , but in most cases there are no digestive symptoms [6] [16] or are mistakenly attributed to poor control of diabetes, gastroparesis or diabetic neuropathy. (wikipedia.org)
- Traditional medicine "fights" Diabetes through drugs that treat the symptoms of the disease, but never deals with the root cause of the disease. (google.com)
- The symptoms of diabetes are related to high blood glucose levels. (womenshealthmag.com)
- The treatment of type 2 diabetes also can produce symptoms, when it leads to the complication of low blood sugar (called hypoglycemia). (womenshealthmag.com)
- Are you informing your patients about prediabetes symptoms or the long-term microvascular and macrovascular complications associated with diabetes mellitus (DM)? (nursingworld.org)
- Disordered gastrointestinal motor and sensory function occurs frequently in both type 1 and type 2 diabetes and may be associated with gastrointestinal symptoms that adversely affect quality of life. (wiley.com)
- 1. Epidemiology of Disordered Gastrointestinal Function and Impact of Chronic Gastrointestinal Symptoms on Quality of Life in Diabetes Mellitus (Johann Hammer, et al. ). (wiley.com)
- The main symptoms of diabetes mellitus are excessive urination, excessive thirst, excessive appetite, and weight loss. (veterinarypartner.com)
- Klaus Dugi, Professor of Medicine at the University of Heidelberg, Germany, discusses the causes, symptoms and treatment of diabetes. (scienceinschool.org)
Patients37
- A Canadian study recently revealed that patients taking statins, including Crestor, may be at an elevated risk of developing diabetes. (amazonaws.com)
- The researchers concluded that, when compared to patients taking low-potency statins, patients taking higher potency statins, such as Crestor, experienced a 15 percent relative increased risk of developing diabetes over a two-year period. (amazonaws.com)
- Do We Need a Patient-Centered Target for Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes Mellitus? (ahajournals.org)
- Equip clinicians at the front line of patient assessment, diagnosis and management with the pre-requisite knowledge and skills to make evidence based decisions on the most appropriate and effective treatment and referral pathways for diabetes mellitus patients. (diabetes.org.uk)
- Thirty percent of patients with diabetes mellitus have some skin lesion that is directly related to the disease or caused by infections, complications or treatments used. (scielo.cl)
- In 56% of patients, diabetes lasted more than 10 years and 52% had some complication of the disease. (scielo.cl)
- Primary treatment goals for diabetes patients include the achieving of blood glucose levels that are as close to normal as possible and the prevention of diabetic complications. (health.am)
- Cardiovascular disease risk is increased in patients with type 1 diabetes. (health.am)
- Primary treatment goals for diabetes patients include the achieving of blood glucose levels. (health.am)
- Pancreatic volume and endocrine and exocrine functions in patients with diabetes. (medscape.com)
- High prevalence of capillary abnormalities in patients with diabetes and association with retinopathy. (medscape.com)
- It is now recognised that upper gastrointestinal motility is pivotal to the regulation of postprandial blood glucose concentrations in both health and patients with diabetes. (wiley.com)
- Many patients with type 2 diabetes also ultimately require insulin therapy as a result of progressive beta cell dysfunction [ 5 ]. (uptodate.com)
- Starter insulin regimens (such as basal insulin monotherapy) for patients with type 2 diabetes commonly require repeated intensification over time to achieve even modest glycated hemoglobin (A1C) reductions [ 6 ]. (uptodate.com)
- Early enteral nutrition and total parenteral nutrition on the nutritional status and blood glucose in patients with gastric cancer complicated with diabetes mellitus after radical gastrectomy Effects of early enteral nutrition (EEN) or total parenteral nutrition (TPN) support on nutritional status and blood glucose in patients with gastric cancer complicated with diabetes mellitus after radical gastrectomy were investigated. (tripdatabase.com)
- Statins may not be appropriate in some patients with diabetes , especially those with severe, chronic malnutrition from pancreatic insufficiency or women planning pregnancy. (tripdatabase.com)
- 114 patients with type 1 diabetes (T1DM) received 0.4 U/kg of each study treatment under automated euglycaemic clamp conditions. (tripdatabase.com)
- We anticipate continued widespread use of this guide in assisting practitioners in the care of their patients with diabetes. (cdc.gov)
- This publication is designed to help the primary care practitioner in the day-to-day management of patients with diabetes. (cdc.gov)
- A companion publication entitled Take Charge of Your Diabetes: A Guide for Patients is available. (cdc.gov)
- Like other chronic illnesses, diabetes mellitus poses a wide range of problems for patients and their family members. (cdc.gov)
- Direct psychological consequences can arise from any one of these factors, making it harder for patients to treat their diabetes and live productive, enjoyable lives. (cdc.gov)
- However, patients with diabetes should continue to monitor their blood glucose and diabetes medications throughout their lives to prevent worsening of the disease and diabetic complications. (nature.com)
- HL-A antigens were determined in 100 patients with diabetes mellitus. (diabetesjournals.org)
- About 90% of patients with diabetes mellitus have Type 2 diabetes. (scienceinschool.org)
- Well known in the art is the use of insulin preparations in medical practice for the treatment of patients suffering from diabetes mellitus. (google.com)
- Why do patients suffering from NonInsulin Dependent Diabetes Mellitus develop hypoglycemia? (answers.com)
- Confidence 70% , - Power 60 % , - Odds ratio 2 , The calculated sample is 60 patients , 30 cases and 30 controls - Cases selection : type 2 diabetes mellitus patients as confirmed by lab diagnosis as documented in their file ,all ages, both sexes, incident cases. (prezi.com)
- Patients suffering from diabetes have numerous oral manifestations and as such dental practitioners must become familiar with this disorder. (agd.org)
- Although there are conflicting guidelines, most agree that patients with hypertension or hyperlipidemia should be screened for diabetes. (aafp.org)
- Diabetes risk calculators have a high negative predictive value and help define patients who are unlikely to have diabetes. (aafp.org)
- Prevention, timely diagnosis, and treatment are important in patients with diabetes mellitus. (aafp.org)
- Patients with a sustained blood pressure of greater than 135/80 mm Hg should be screened for diabetes. (aafp.org)
- Patients with hypertension or hyperlipidemia should be screened for diabetes. (aafp.org)
- Risk calculators can be used to determine which patients do not need screening for diabetes. (aafp.org)
- Patients at increased risk of diabetes should be counseled on effective strategies to lower their risk, such as weight loss and exercise. (aafp.org)
- Latent autoimmune diabetes in adults includes a heterogenous group of conditions that are phenotypically similar to type 2 diabetes, but patients have autoantibodies that are common with type 1 diabetes. (aafp.org)
Diagnosis of diabetes7
- The current classification and diagnosis of diabetes used in the U.S. was developed by the National Diabetes Data Group (NDDG) and published in 1979 [ 1 ] . (medscape.com)
- An international Expert Committee, working under the sponsorship of the American Diabetes Association, was established in May 1995 to review the scientific literature since 1979 and to decide if changes to the classification and diagnosis of diabetes were warranted. (medscape.com)
- New recommendations for the diagnosis of diabetes have changed the epidemiology of DM. (nih.gov)
- International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. (medscape.com)
- The key to prevention is careful control of blood sugar levels just as soon as the diagnosis of diabetes is made. (hopkinsmedicine.org)
- Over time with a diagnosis of diabetes, the interplay between these hormones becomes dysfunctional and increases the risk of hypoglycemia ( Unger, 2013 ). (nursingcenter.com)
- [12] [13] Diagnosis of diabetes is by blood tests such as fasting plasma glucose , oral glucose tolerance test , or glycated hemoglobin (A1C). (wikipedia.org)
TIPO5
- A Diabetes Tipo 1 atinge cerca de 3200 crianças e jovens com idades entre os 0 e os 19 anos. (slideshare.net)
- 13. Diabetes tipo 1 O TRATAMENTO da Diabetes tipo 1 tem como objectivo a manutenção da glicémia dentro dos parâmetros aconselhados para a idade. (slideshare.net)
- Diabetes Tipo 1. (slideshare.net)
- La diabetes mellitus (que también se conoce como la "diabetes sacarina") es un trastorno que ocurre cuando el cuerpo no puede utilizar la glucosa (un tipo de azúcar) en forma normal. (rchsd.org)
- Cuando una persona padece de diabetes, el páncreas no produce suficiente insulina ( diabetes tipo 1 ) o el cuerpo no es capaz de responder en forma normal a la insulina que se genera ( diabetes tipo 2 ). (rchsd.org)
Search1
- A genome-wide search for human type 1 diabetes susceptibility genes. (medscape.com)
Chronic disease4
- Type 2 diabetes is a chronic disease. (womenshealthmag.com)
- DIABETES MELLITUS IS A CHRONIC DISEASE that is growing in prevalence worldwide. (cmaj.ca)
- Type 2 diabetes is typically a chronic disease associated with a ten-year-shorter life expectancy. (wikipedia.org)
- Diabetes mellitus is a chronic disease affecting all age groups. (agd.org)
Screening5
- The American Diabetes Association recommends screening for undiagnosed type 2 diabetes at the first prenatal visit in women with diabetes risk factors. (hopkinsmedicine.org)
- It is also recommended that women with a history of GDM undergo lifelong screening for the development of diabetes or prediabetes at least every three years. (hopkinsmedicine.org)
- In this light, pregnancy affords a unique opportunity for diabetes screening and may well be the best opportunity in a woman's life to discover or prevent her diabetes. (health.am)
- Screening for diabetes (position statement). (washington.edu)
- Diabetes screening is done using blood tests like fasting blood sugar and hemoglobin A1c levels. (medindia.net)
Etiology2
- the growth of knowledge regarding the etiology and pathogenesis of diabetes has led many individuals and groups in the diabetes community to express the need for a revision of the nomenclature, diagnostic criteria, and classification of diabetes. (medscape.com)
- Recognize the prevalence, incidence and etiology of diabetes mellitus. (agd.org)
Metabolic disorder1
- Of Diabetes Mellitus Introduction Methedology Conclusion Diabetes mellitus is a metabolic disorder resulting from a defect in insulin secretion, insulin action, or both. (prezi.com)
Complications of diabe6
- To avoid late complications of diabetes and related costs, primary prevention and early treatment are therefore necessary. (hindawi.com)
- Diabetic neuropathies are the most common complications of diabetes affecting. (health.am)
- The 1982 publication of The Prevention and Treatment of Five Complications of Diabetes: A Guide for Primary Care Practitioners was an initial attempt to provide straightforward and practical information that primary care practitioners could immediately apply in their practice in the diagnosis and prevention of complications of diabetes. (cdc.gov)
- The scope of the present revised edition has been broadened to cover nine complications of diabetes, and the recommendations for the previous five. (cdc.gov)
- The recommendations relate to the prevention, detection, and treatment of the major complications of diabetes. (cdc.gov)
- We will review the oral manifestations and complications of diabetes mellitus and the common medical emergencies that may be encountered in the dental office. (agd.org)
Autoimmune8
- Both these conditions are associated with inflammation and type-1 diabetes also with an autoimmune pathology. (springer.com)
- Around 1 in 7 people with type 1 diabetes suffer from a condition called type 2 polyglandular autoimmune syndrome and these individuals have parathyroid and adrenal gland disorders in addition to type 1 diabetes. (news-medical.net)
- This latter group is now said to have latent autoimmune diabetes of the adult [LADA]. (medscape.com)
- Attaining deficiency in insulin production in type 1 diabetes mellitus can occur by a variety of different mechanisms ranging from chemical ablation of the beta cells to breeding rodents that spontaneously develop autoimmune diabetes. (hindawi.com)
- Is Diabetes An Autoimmune Disease? (dlife.com)
- Prevalence of Type 1 diabetes autoantibodies (GAD and IA2) in Sardinian children and adolescents with autoimmune thyroiditis. (medscape.com)
- Type 1 diabetes mellitus (T1DM) is an autoimmune disease that can develop due to i.e. heredity, exposure to infections and stress-strain. (tripdatabase.com)
- 7 Type 1 diabetes accounts for 5 to 10 percent of persons with diabetes 6 and is characterized by insulin deficiency that is typically an autoimmune-mediated condition. (aafp.org)
Https2
- Retrieved on September 21, 2019 from https://www.news-medical.net/health/Diabetes-Mellitus-Type-1-Inheritance.aspx. (news-medical.net)
- Retrieved on February 27, 2021 from https://www.news-medical.net/health/Diabetic-Mastopathy-Complication-of-Diabetes-Mellitus.aspx. (news-medical.net)
Pathogenesis of diabetes4
- Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease. (nih.gov)
- Thus, all chapters have been significantly revised and updated with current evidence and best practices, and four brand new chapters are included, discussing the potential role of vitamin D in the pathogenesis of diabetes, peculiarities of diabetes in the elderly, oral manifestations of diabetes, and the current state of bariatric surgery. (springer.com)
- In order to better understand the role of each drug class in the treatment of diabetes, it is important to have a basic understanding of the pathogenesis of diabetes ( Fig. 1 ) and the interplay between insulin and glucose at different sites. (cmaj.ca)
- The increase in lipolysis by adipose cells that are resistant to insulin and the subsequent increased levels of circulating free fatty acids also contribute to the pathogenesis of diabetes by impairing β-cell function, impairing glucose uptake in skeletal muscles and promoting glucose release from the liver. (cmaj.ca)
Pregnancy5
- GDM appears to result from the same broad spectrum of physiological and genetic abnormalities that characterize diabetes outside of pregnancy. (nih.gov)
- Preexisting diabetes (ie, diabetes diagnosed prior to pregnancy) affects approximately 1-3 pregnancies per 1000 births. (health.am)
- In spite of the goal of preconception counseling for women with preexisting diabetes, many women will present for medical care for the first time during pregnancy. (health.am)
- Currently, the major challenges of caring for diabetics in pregnancy are first, to enhance preconceptual glucose control and reduce the risk of associated congenital malformations, second to adequately screen pregnant women, and third, to detail the full impact of milder glucose elevations, not only on maternal risk for developing diabetes, but also on immediate and long-term consequences to the fetus/child. (health.am)
- The definition applies regardless of insulin use for treatment or the persistence of the condition after pregnancy, and does not exclude the possibility that unrecognized glucose intolerance or overt diabetes may have preceded the pregnancy. (clinicaltrials.gov)
Glycemic Control3
- Despite advances in options for the treatment of diabetes, optimal glycemic control is often not achieved [ 1 ]. (uptodate.com)
- Pharmacologic therapy is often necessary to achieve optimal glycemic control in the management of diabetes. (cmaj.ca)
- 8 Although nonpharmacologic therapy (e.g., diet, exercise and weight loss) remains a critical component in the treatment of diabetes, pharmacologic therapy is often necessary to achieve optimal glycemic control. (cmaj.ca)
Blood glucose levels1
- Diabetes mellitus disease, commonly known as diabetes, is a group of metabolic disorders characterized by high blood glucose levels for a prolonged time. (hindawi.com)
Pathophysiology4
- In type 2 diabetes (T2D) mellitus, numerous animal models have been developed for understanding the pathophysiology of diabetes and its complications [ 10 ]. (hindawi.com)
- Disease Pathophysiology and Treatment of Type 1 Diabetes Mellitus Rogelio Gonzales University of Texas Rio Grande Valley 1. (bartleby.com)
- In this webinar we will review the pathophysiology and pharmacotherapy commonly used to treat diabetes. (agd.org)
- Understand (a) the pathophysiology and (b) pharmacotherapy of diabetes. (agd.org)
20171
- When deciding to start a statin, consider the 23 UMHS Management of Type 2 Diabetes Mellitus June, 2017 patient's 10 year ASCVD risk, nutritional status and life expectancy. (tripdatabase.com)
MedlinePlus1
- Another online website with information on diabetes mellitus is MedlinePlus. (reference.com)
Endocrine2
- Type 1 diabetes mellitus (T1DM) is the most common metabolic endocrine disease in children. (dlife.com)
- Introduction "Diabetes mellitus, by far the most common of all endocrine disorders, is one of the foremost public health concerns confronting the world today. (bartleby.com)
Treatment18
- In 2012, the three largest competitors in the market for diabetes diagnosis, treatment and drug delivery competed exclusively in the insulin and insulin pen markets. (amazonaws.com)
- Our firm is pursuing lawsuits on behalf of consumers who have been diagnosed with Type 2 diabetes and other injuries following treatment with Crestor. (amazonaws.com)
- Johnson & Johnson's best-selling medicines continued to post strong growth, with increased demand for medicines including the arthritis drug Remicade, prostate cancer drug Zytiga, seen here, blood thinner Xarelto, diabetes drug Invokana and psoriasis treatment Stelara. (amazonaws.com)
- The sulfonylureas are oral hypoglycemic agents used as adjuncts to diet and exercise in the treatment of type 2 diabetes. (britannica.com)
- treatment of type II (non-insulin-dependent) diabetes. (britannica.com)
- The dramatic benefits of intensive insulin therapy led the American Diabetes Association to issue a position statement declaring that the primary treatment goal in type 1 diabetes should be to attain blood glucose control "at least equal to that in the intensively treated cohort" of the DCCT. (health.am)
- Over 3 million persons in the United States are sufficiently affected by diabetes mellitus to warrant treatment with insulin or oral hyperglycemics. (health.am)
- Culture counts: why current treatment models fail Hispanic women with type 2 diabetes. (washington.edu)
- Methods of treating diabetes mellitus in a patient in need of such treatment include administering an effective amount of an insulin polypeptide-oligomer conjugate of formula V to the patient in order to treat diabetes mellitus in the patient. (google.com)
- Treatment of type 1 diabetes is directed at physiologic insulin replacement. (uptodate.com)
- See 'Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes mellitus' . (uptodate.com)
- The cost-effectiveness of insulin analogues depends on the type of insulin analogue and whether the patient receiving the treatment has type 1 or type 2 diabetes. (cmaj.ca)
- Insulin agents available for the treatment of diabetes mellitus include conventional insulins and insulin analogues. (cmaj.ca)
- Hypoglycemia is a serious acute complication of diabetes treatment. (nursingcenter.com)
- Hypoglycemia is an acute complication of diabetes treatment and is regarded as the main limiting factor in tight glucose control. (nursingcenter.com)
- A pharmaceutical preparation for the treatment of diabetes mellitus comprising the following components, in percent by weight: ______________________________________ crystalline insulin with a conventional 1 to 25.0activity of 1 mg = 20 unitsadditives inhibiting deactivation of insulin, 0.02 to 10.0viz. (google.com)
- The present invention relates to the art of pharmacy and, more specifically, to a novel pharmaceutical preparation for the treatment of diabetes mellitus. (google.com)
- Other new chapters cover retinopathy, cardiovascular disease, wound healing, and treatment of women with diabetes. (ovid.com)
Commonly3
- Diabetes mellitus ( DM ), commonly referred to as diabetes , is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period. (wikipedia.org)
- Those diagnosed with Type 1 diabetes commonly supplement their diets with insulin, injected just under the fatty tissue of the skin. (reference.com)
- Diabetes mellitus, more commonly known as diabetes, is a disease in which the body does not produce and/or properly use insulin, a hormone that aids the body in converting sugars and other foods into energy. (google.com)
Nutrition1
- Overall, a nutrition plan for a person with diabetes includes 10-20% of calories from protein, no more than 30% of calories from fats (with no more than 10% from saturated fats), and the remaining 50-60% from carbohydrates. (medindia.net)
19921
- 1992). Diabetes mellitus in Egypt / Morsi Arab. (who.int)
Diabetic diet1
- The Diabetic Diet Weight gain and blood sugar spikes are the bane of the diabetic attempting to enjoy life and eating and still keep diabetes in check. (angelfire.com)
Juvenile diabetes2
- Individuals diagnosed with type 1 diabetes (also known as juvenile diabetes) are incapable of producing pancreatic insulin and must rely on insulin medication for survival. (norml.org)
- When the data are combined with that from other studies, there is a definite positive association of acute-onset juvenile diabetes mellitus with HL-A8 and W15. (diabetesjournals.org)
Hypoglycemia1
- The risk of hypoglycemia increases as endogenous insulin decreases and the patient must rely on insulin injections ( McCall, 2014 ) making those with type 1 diabetes much more likely to experience hypoglycemia than their type 2 counterparts. (nursingcenter.com)
Diseases8
- This website is about managing, curing diabetes and other chronic diseases by following Natural life style changes . (google.com)
- Diabetes mellitus refers to a number of diseases that have in common elevated blood sugar levels. (wikiversity.org)
- Natural News) Diabetes is one of the most common types of non-communicable diseases that kills millions of people yearly. (naturalnews.com)
- A Koebner phenomenon resulting from deep self-inflicted scratches is thought to be a possible mechanism for this condition, which is often associated with diseases such as chronic renal insufficiency, diabetes mellitus, herpes zoster, or scabies. (aerzteblatt.de)
- Diabetes or as doctors would refer by as diabetes mellitus, is a group of metabolic diseases in which a person has a high blood glucose level (above 110 mg/dL) because insulin production is inadequate, the body's cells do not respond properly to insulin or even both. (bartleby.com)
- [10] Diabetes was one of the first diseases described. (wikipedia.org)
- Diabetes mellitus (diabetes) is a group of metabolic diseases, characterized by high blood sugar, caused by either body not producing enough insulin, or because body does not respond to the produced insulin. (snpedia.com)
- Diabetes are genetic diseases that include both monogenic and polygenic versions. (snpedia.com)
Metabolism5
- However, abnormal glucose metabolism can be documented years before the onset of overt diabetes. (uptodate.com)
- In order to understand the problems involved in diabetes mellitus it is necessary to understand something of the normal body's sugar metabolism. (veterinarypartner.com)
- Diabetes mellitus mostly involves the metabolism of sugar (in particular, a sugar known as glucose ) so we will focus on the sugar part of the situation. (veterinarypartner.com)
- Diabetes mellitus is a hereditary or developmental disease marked by a disorder of carbohydrate metabolism caused by abnormal insulin levels. (medical-guides.com)
- Hereditary disorder affecting iron metabolism in which excessive amounts of iron accumulate in the body tissues, characterized by diabetes mellitus, liver dysfunction, and a bronze pigmentation of the skin. (citizendium.org)
Incidence of Type1
- Indeed, animal and human studies support the notion that adequate vitamin-D supplementation may decrease the incidence of type-1 and possibly also of type-2 diabetes mellitus and may improve the metabolic control in the diabetes state. (springer.com)
Neonatal12
- Individuals with permanent neonatal diabetes mellitus experience slow growth before birth (intrauterine growth retardation). (medlineplus.gov)
- In some cases, people with permanent neonatal diabetes mellitus also have certain neurological problems, including developmental delay and recurrent seizures (epilepsy). (medlineplus.gov)
- This combination of developmental delay, epilepsy, and neonatal diabetes is called DEND syndrome. (medlineplus.gov)
- The remainder are considered to have permanent neonatal diabetes mellitus. (medlineplus.gov)
- Permanent neonatal diabetes mellitus may be caused by mutations in several genes. (medlineplus.gov)
- About 30 percent of individuals with permanent neonatal diabetes mellitus have mutations in the KCNJ11 gene. (medlineplus.gov)
- An additional 20 percent of people with permanent neonatal diabetes mellitus have mutations in the ABCC8 gene. (medlineplus.gov)
- Mutations in the KCNJ11 or ABCC8 gene that cause permanent neonatal diabetes mellitus result in K-ATP channels that do not close, leading to reduced insulin secretion from beta cells and impaired blood sugar control. (medlineplus.gov)
- Mutations in the INS gene, which provides instructions for making insulin, have been identified in about 20 percent of individuals with permanent neonatal diabetes mellitus. (medlineplus.gov)
- Permanent neonatal diabetes mellitus can also be caused by mutations in other genes, some of which have not been identified. (medlineplus.gov)
- Permanent neonatal diabetes mellitus can have different inheritance patterns. (medlineplus.gov)
- When permanent neonatal diabetes mellitus is caused by mutations in the ABCC8 gene, it may be inherited in either an autosomal dominant or autosomal recessive pattern . (medlineplus.gov)
Affects5
- GUELPH, ON , Aug. 6, 2019 /CNW/ - Diabetes mellitus (DM) affects between 0.2 - 1% of cats in the general population. (newswire.ca)
- Type 2 diabetes affects all parts of the body. (womenshealthmag.com)
- It is estimated that diabetes affects 387 million people worldwide [ 1 ]. (uptodate.com)
- Diabetes is chronic lifelong condition that affects your body's ability to use the energy found in food. (smore.com)
- Diabetes affects 8.3% Americans and about 10% Indians. (medindia.net)
Increased urination1
- If diabetes is not under control - or a person doesn't know he or she has diabetes - the person may have problems like increased urination (peeing), extreme thirst, and unexplained weight loss. (kidshealth.org)
Prevention3
- Prevention of type 2 diabetes - where is the evidence? (who.int)
- Magnitude of diabetes mellitus: - Promotion and prevention of the occurrence of diabetes can be achieved by awareness of people about these risk factors and how to avoid. (prezi.com)
- At the same time the chart reviews were conducted, the Maternal and Infant Health Program and the Diabetes Prevention and Control Program teamed up to develop patient education materials for women with GDM. (cdc.gov)
Occurs4
- Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the body can't use glucose (a type of sugar) normally. (kidshealth.org)
- Brittle diabetes occurs no more frequently than in 1% to 2% of diabetics. (wikipedia.org)
- However, since SGLT2 inhibitors have been approved, there have been reports of ketoacidosis, a serious condition that usually only occurs in type 1 diabetes when insulin levels are too low. (washington.edu)
- Type 2 diabetes occurs when your body's cells do not react efficiently to insulin. (womenshealthmag.com)
Diet6
- Type 2 diabetes is a less serious condition that typically is controlled by diet. (norml.org)
- Many have turned their diabetes around with diet and exercise, particularly if they implement major wholistic health changes as soon as they know they are pre-diabetic or diabetic. (angelfire.com)
- Even so, exercise and watching one's diet can dramatically and positively affect the quality of life for those with various types of diabetes. (wikiversity.org)
- A patient whose diabetes is controlled with diet or an oral antidiabetic agent clearly has type 2 DM. (medscape.com)
- If untreated and not controlled through diet and medication, diabetes mellitus can become life-threatening. (reference.com)
- Effective treatments for type 1 diabetes include insulin injections or pumps, blood sugar monitoring, a healthy diet that distributes carbohydrates through. (reference.com)
Forms of diabetes2
- Phenotypically this type of mitochondrial diabetes is combined with deafness in more than 60% and is clinically distinguishable with respect to several characteristics from the two idiopathic forms of diabetes. (nih.gov)
- There are many forms of diabetes (Pre-diabetes, Type 1 diabetes, and Type 2 diabetes) and thousands of undiagnosed people world-wide. (wikiversity.org)
20191
- 2019. Diabetes Mellitus Type 1 Inheritance . (news-medical.net)
Risk29
- [16] Diabetes at least doubles a person's risk of early death. (wikipedia.org)
- The association of celiac disease with type 1 diabetes increases the risk of complications, such as retinopathy and mortality. (wikipedia.org)
- Indeed, women with GDM are at high risk for having or developing diabetes when they are not pregnant. (nih.gov)
- Several observational trials have reported that those with a history of cannabis use possess a lower risk of type 2 diabetes than do those with no history of use. (norml.org)
- In early 2013, Health Canada called on statin makers to update their labels to include a warning about the increased risk of diabetes from statins. (amazonaws.com)
- Other studies have found that statin use was also associated with an increased risk for Type 2 diabetes, that statins may actually minimize exercise benefits in obese adults, and that there may be a tie between statins and kidney damage. (amazonaws.com)
- This section of the wellness library lists all the available articles we have posted so far on the subject of diabetes-related complications as well as statistic on teen diabetes and other health information of interest to those at risk for developing this condition. (angelfire.com)
- Diabetes mellitus (DM) is a major public health problem worldwide, and it is a known risk factor for coronary artery disease (CAD). (nih.gov)
- Type 1 diabetes is an inherited condition and individuals with a first degree relative who has the condition are at an increased risk of developing the condition. (news-medical.net)
- In men with type 1 diabetes, the risk of their child also developing the condition is one in 17. (news-medical.net)
- In women with type 1 diabetes who have their baby before the age of 25, the risk of the child developing the condition is one in 25. (news-medical.net)
- If both parents have type 1 diabetes, the risk of the condition developing in offspring varies between 1 in 4 and 1 in 10. (news-medical.net)
- Carrying these genes raises the risk that offspring will inherit type 1 diabetes. (news-medical.net)
- risk of metabolic syndrome and type 2 diabetes. (britannica.com)
- Recent studies show that taking statins, or drugs that lower blood cholesterol, have a 30 percent chance in increasing the risk of developing type-2 diabetes. (naturalnews.com)
- The prevalence of and risk factors for type 2 diabetes will be reviewed here. (uptodate.com)
- In an analysis of data from the 2011 to 2014 Behavioral Risk Factor Surveillance System, the prevalence of self-reported diabetes was higher among Asians (9.9 percent) and Native Hawaiians or other Pacific Islanders (14.3 percent) than in white individuals (8 percent) [ 6 ]. (uptodate.com)
- Although the lifetime risk of type 2 diabetes is high, our ability to predict type 2 diabetes in the general population is limited. (uptodate.com)
- Although the risk of developing type 2 diabetes follows a continuum across all levels of abnormal glycemia, when classified categorically, the individuals demonstrably at highest risk include those with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or a glycated hemoglobin (A1C) level of 5.7 to 6.4 percent (39 to 46 mmol/mol) ( table 1 ) [ 9,10 ]. (uptodate.com)
- A growing number of studies link shift work with an increased risk for type 2 diabetes mellitus. (cdc.gov)
- The Harvard Nurses Study followed a group of women for 18 to 20 years and examined rotating night shifts (at least 3 nights per month) and risk for diabetes. (cdc.gov)
- Monk and colleagues found that retirees whose shifts were fixed or rotating and overlapped midnight to 6 a.m. had double the risk of self-reported diabetes compared to former daytime workers. (cdc.gov)
- To reduce the risk for developing a variety of chronic illnesses including diabetes and cardiovascular disease, researchers recommend efforts to adapt circadian rhythms to work times as well as efforts to achieve sufficient sleep. (cdc.gov)
- HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. (medscape.com)
- Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. (washington.edu)
- Diabetes itself does not cause changes in personality or psychiatric illness, but particular subgroups of the diabetic population appear to be at risk for developing psychosocial problems. (cdc.gov)
- Risk factors : - The cornerstone is that diabetes can be prevented and can be controlled through controlling its risk factors. (prezi.com)
- Women diagnosed with GDM have a 20%-50% lifetime risk of developing type 2 diabetes. (cdc.gov)
- The risk of diabetes is increased in close relatives suggesting a genetic predisposition, although no direct genetic link has been identified. (aafp.org)
Insulina5
- O termo diabetes mellitus descreve uma desordem metabólica de etiologia múltipla, caracterizada por uma hiperglicemia crónica com distúrbios no metabolismo dos hidratos de carbono, lípidos e proteínas, resultantes de deficiências na secreção ou acção da insulina, ou de ambas. (slideshare.net)
- Es un síndrome metabólico consistente en hiperglucemia, glucosuria, polifagia, polidipsia, poliuria y alteraciones en el metabolismo de los lípidos y de las proteínas como consecuencia de un déficit absoluto o relativo en la acción de la insulina. (slideshare.net)
- Es un transtorno complejo y multifactorial en el que existe tanto una alteración de la liberación, con déficit relativo de insulina, como una reistencia a ella en los órganos efectores. (slideshare.net)
- Una hormona llamada "insulina" controla los niveles de glucosa en la sangre. (rchsd.org)
- La insulina ayuda a que la glucosa entre en las células. (rchsd.org)
20012
- Diabetes Care 2001;24(suppl 1):S21-24. (washington.edu)
- Under a federal court decision, Vietnam Veterans are eligible for retroactive awards of benefits for their diabetes if you applied for service-connection for diabetes before the VA diabetes regulation went into effect on May 8, 2001. (va.gov)