Thogotovirus: A genus of the family ORTHOMYXOVIRIDAE comprising tick-borne viruses occasionally infecting humans. Dhori and Thogoto viruses were formerly thought to be members of BUNYAVIRIDAE. Thogoto virus is the type species.Myxovirus Resistance Proteins: Interferon-induced DYNAMIN-like GTP-binding proteins localized in the cytoplasm, nuclear pore complex and nucleus. They play a role in antiviral defense and immunity.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.Siberia: A region, north-central Asia, largely in Russia. It extends from the Ural Mountains to the Pacific Ocean and from the Arctic Ocean to central Kazakhstan and the borders of China and Mongolia.Hemagglutinins, Viral: Specific hemagglutinin subtypes encoded by VIRUSES.Hemagglutinin Glycoproteins, Influenza Virus: Membrane glycoproteins from influenza viruses which are involved in hemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of HA glycoproteins and nine of NA glycoproteins have been identified from INFLUENZA A VIRUS; no subtypes have been identified for Influenza B or Influenza C viruses.Orthomyxoviridae: A family of RNA viruses causing INFLUENZA and other diseases. There are five recognized genera: INFLUENZAVIRUS A; INFLUENZAVIRUS B; INFLUENZAVIRUS C; ISAVIRUS; and THOGOTOVIRUS.Neuromyelitis Optica: A syndrome characterized by acute OPTIC NEURITIS; MYELITIS, TRANSVERSE; demyelinating and/or necrotizing lesions in the OPTIC NERVES and SPINAL CORD; and presence of specific autoantibodies to AQUAPORIN 4.KansasAnemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.Aquaporin 4: Aquaporin 4 is the major water-selective channel in the CENTRAL NERVOUS SYSTEM of mammals.Ticks: Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)Avihepadnavirus: A genus of HEPADNAVIRIDAE infecting birds but rarely causing clinical problems. Transmission is predominantly vertical. HEPATITIS B VIRUS, DUCK is the type species.Encephalitis Virus, Eastern Equine: A species of ALPHAVIRUS causing encephalomyelitis in Equidae and humans. The virus ranges along the Atlantic seaboard of the United States and Canada and as far south as the Caribbean, Mexico, and parts of Central and South America. Infections in horses show a mortality of up to 90 percent and in humans as high as 80 percent in epidemics.Rift Valley fever virus: A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.Rift Valley Fever: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.Norwalk virus: The type species in the genus NOROVIRUS, first isolated in 1968 from the stools of school children in Norwalk, Ohio, who were suffering from GASTROENTERITIS. The virions are non-enveloped spherical particles containing a single protein. Multiple strains are named after the places where outbreaks have occurred.Rotavirus: A genus of REOVIRIDAE, causing acute gastroenteritis in BIRDS and MAMMALS, including humans. Transmission is horizontal and by environmental contamination. Seven species (Rotaviruses A thru G) are recognized.Hepatitis B Virus, Duck: A DNA virus that closely resembles human hepatitis B virus. It has been recovered from naturally infected ducks.
... is an RNA virus in the genus Thogotovirus of the family Orthomyxoviridae, which is similar to Dhori virus and ... Thogoto virus caused disease in two people from Nigeria, one of whom died; Dhori virus caused disease in five laboratory ... The virus was named "Bourbon virus" for the county in which it originated. Bourbon virus is a type of thogotovirus, which is in ... Bourbon virus is most similar in RNA sequence to Dhori virus and the closely related Batken virus, both members of the genus ...
... (DHOV) is a species of the genus Thogotovirus and a member of the family Orthomyxoviridae. Its hosts are ticks, ... Batken virus (BKNV) is considered a subtype of Dhori virus. Serological cross-reactions between Batken and Dhori viruses ... Li G, Wang N, Guzman H, Sbrana E, Yoshikawa T, Tseng CT, Tesh RB, Xiao SY (2008). "Dhori virus (Orthomyxoviridae: Thogotovirus ... Batken virus is an orthomyxovirus closely related to Dhori virus". J. Gen. Virol. 78 ( Pt 10): 2453-8. doi:10.1099/0022-1317-78 ...
Johnston Atoll virus Quaranfil virus Genus: Thogotovirus Dhori virus Thogoto virus Family: Unassigned Genus: Deltavirus ... virus Shuni virus Simbu virus Tacaiuma virus Tete virus Thimiri virus Timboteua virus Turlock virus Wyeomyia virus Zegla virus ... virus Uganda S virus Usutu virus Wesselsbron virus West Nile virus Yaounde virus Yellow fever virus Yokose virus Zika virus ... Capim virus Caraparu virus Catu virus Estero Real virus Gamboa virus Guajara virus Guama virus Guaroa virus Kaeng Khoi virus ...
Thogoto virus (THOV) is the type species; the genus also contains the species Dhori virus (DHOV) and its subtype Batken virus, ... 2008), "[Isolation of influenza virus A (Orthomyxoviridae, Influenza A virus), Dhori virus (Orthomyxoviridae, Thogotovirus), ... as well as the species or strains Araguari virus, Aransas Bay virus (ABV), Bourbon virus, Jos virus (JOSV) and Upolu virus ( ... "Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus", Journal of Virology, 69: 3904-09 Berger SA, Calisher ...
Thogotovirus Thogotovirus* Tick, mosquito, mammal (including human) Dhori virus Batken virus, Bourbon virus, Jos virus ... Influenza virus A Influenza A virus* H1N1, H1N2, H2N2, H3N1, H3N2, H3N8, H5N1, H5N2, H5N3, H5N8, H5N9, H7N1, H7N2, H7N3, H7N4, ... International Committee on Taxonomy of Viruses Index of Viruses - Orthomyxovirus (2006). In: ICTVdB-The Universal Virus ... Jones LD, Nuttall PA (1989). "Non-viraemic transmission of Thogoto virus: influence of time and distance". Trans. R. Soc. Trop ...
Johnston Atoll virus Quaranfil virus Genus: Thogotovirus Dhori virus Thogoto virus There are four genera of influenza virus, ... Influenza virus A, Influenza virus B, Influenza virus C, Influenza virus D, Isavirus, Thogotovirus and Quaranjavirus. The first ... After the release of new influenza virus, the host cell dies. Orthomyxoviridae viruses are one of two RNA viruses that ... Influenza B virus Genus: Influenzavirus C Influenza C virus Genus: Isavirus Infectious salmon anemia virus Genus: Quaranjavirus ...
... nairovirus Thimiri orthobunyavirus Thin paspalum asymptomatic virus Thistle mottle virus Thogoto virus Thosea asigna virus ... entomopoxvirus Desmodium leaf distortion virus Desmodium yellow mottle virus Desmodus rotundus polyomavirus 1 Dhori virus ... virus A Potato virus H Potato virus M Potato virus P Potato virus S Potato virus T Potato virus U Potato virus V Potato virus X ... virus Garlic virus A Garlic virus B Garlic virus C Garlic virus D Garlic virus E Garlic virus X Gayfeather mild mottle virus ...
Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus.. M Frese, G Kochs, U Meier-Dieter, J Siebler, O Haller ... Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus.. M Frese, G Kochs, U Meier-Dieter, J Siebler, O Haller ... Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus.. M Frese, G Kochs, U Meier-Dieter, J Siebler, O Haller ... Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus. Message Subject (Your Name) has forwarded a page to ...
Because of the relationship of DHOV to the influenza viruses, its biosafety level 2 status, and its similar pathology in mice, ... and realistic animal model for studies on the pathogenesis and management of H5N1 virus infection. ... with many of the clinical and pathologic findings seen in mice infected with H5N1 highly pathogenic avian influenza A virus. ... or intraperitoneal infection with Dhori virus (DHOV), adult mice developed a fulminant and uniformly fatal illness ...
However, in mice carrying defects in the type I and type II interferon system, the virus grew to high titers and caused severe ... We analyzed the pathology of BRBV infection in mice and found a high sensitivity of the virus to the host interferon system. ... Infected standard laboratory mice did not show clinical signs or virus replication. ... Bourbon virus (BRBV) is a recently discovered tick-transmitted viral pathogen that is prevalent in the Midwest and southern ...
Dhori virus (DHOV) is a species of the genus Thogotovirus and a member of the family Orthomyxoviridae. Its hosts are ticks, ... Batken virus (BKNV) is considered a subtype of Dhori virus. Serological cross-reactions between Batken and Dhori viruses ... Li G, Wang N, Guzman H, Sbrana E, Yoshikawa T, Tseng CT, Tesh RB, Xiao SY (2008). "Dhori virus (Orthomyxoviridae: Thogotovirus ... Batken virus is an orthomyxovirus closely related to Dhori virus". J. Gen. Virol. 78 ( Pt 10): 2453-8. doi:10.1099/0022-1317-78 ...
... and C viruses; infectious salmon anemia virus; Dhori virus; and Thogoto virus (online Technical Appendix Table 4) (8-10).. ... The family of viruses that contains the three genera of influenza viruses, types A and B, C, and Thogoto-like viruses. Virions ... a family of viruses containing influenza viruses A, B and C of which only influenza A viruses cause disease in domestic animals ... See also: Influenza virus. Or·tho·myx·o·vir·i·dae (ōrthō-miksō-viri-dē) The family of viruses that comprises the three ...
Bourbon virus is an RNA virus in the genus Thogotovirus of the family Orthomyxoviridae, which is similar to Dhori virus and ... Thogoto virus caused disease in two people from Nigeria, one of whom died; Dhori virus caused disease in five laboratory ... The virus was named "Bourbon virus" for the county in which it originated. Bourbon virus is a type of thogotovirus, which is in ... Bourbon virus is most similar in RNA sequence to Dhori virus and the closely related Batken virus, both members of the genus ...
Resistance to infection with two tick-borne viruses, Thogoto virus (J:8273) and Dhori virus (J:27760), is also conferred by Mx1 ... a condition thought to be due to the replication of MCF virus, Rmcfr increases resistance to the virus-induced erythroleukemia ... Although some interferon-induced genes respond directly to virus invasion as well as indirectly through induction by virus- ... The CBA/J, CE/J, I/LnJ, and PERA/Ei strains, also susceptible to the virus, have another form of the Mx1s2 allele in which ...
Resistance to infection with two tick-borne viruses, Thogoto virus (J:8273) and Dhori virus (J:27760), is also conferred by Mx1 ... Although some interferon-induced genes respond directly to virus invasion as well as indirectly through induction by virus- ... The CBA/J, CE/J, I/LnJ, and PERA/Ei strains, also susceptible to the virus, have another form of the Mx1s2 allele in which ... A murine leukimia virus (Xmv-28) insertion in reverse orientation in intron 1 is found in all mouse strains with the rd1 ...
... has reported the discovery of a new virus that may have contributed to the death of a resident in eastern Kansas in late spring ... Antibodies against Thogoto virus have been identified in humans in Europe, Asia, and Africa; antibodies against Dhori virus ... RELATED: What is the Bourbon Virus? The ≥6 viruses in the genus Thogotovirus are mainly associated with either hard or soft ... Phylogenetic analyses reveal that the Bourbon virus is most closely related to Dhori and Batken viruses. ...
Isolation of influenza virus A (Orthomyxoviridae, influenza A virus), Dhori virus (Orthomyxoviridae, Thogotovirus), and ... avian influenza virus (Albini et al. 2014), avian paramyxovirus (Schelling et al. 1999), and West Nile virus (Iashkulov et al. ... Serosurvey for Newcastle disease and avian influenza a virus antibodies in great cormorants from France. J Wildlife Dis. 2002; ... Newcastles disease virus (Paromyxoviridae, Avulavirus) on the Malyi Zhemchuzhnyi Island in the north-western area of the ...
Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus.J. Virol. 69 1995 3904 3909 ... Thogoto virus (Orthomyxoviridae), vesicular stomatitus virus (VSV) (Rhabdoviridae), measles virus (MV), human parainfluenza ... Tick-borne Thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1.J. Virol. 69 1995 ... Mx1 but not MxA confers resistance against tick-borne Dhori virus in mice.Virology 211 1995 296 301 ...
31.6.1 Thogoto virus 591. 31.6.2 Dhori virus 592. 31.7 Other tick-transmitted viruses 592 ... 30 Borna Disease Virus And The Search For Human Infection 557. Kathryn M. Carbone and Juan Carlos de la Torre. 30.1 ... 19 New, Emerging, And Reemerging Respiratory Viruses 355. Fleur M. Moesker, Pieter L.A. Fraaij, and Albert D.M.E. Osterhaus. ... 11 Biological Significance Of Bats As A Natural Reservoir Of Emerging Viruses 195. Angela M. Bosco-Lauth and Richard A. Bowen ...
Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus. Frese, M., Kochs, G., Meier-Dieter, U., Siebler, J. & ... Mx1 but Not MxA Confers Resistance against Tick-Borne Dhori Virus in Mice. Thimme, R., Frese, M., Kochs, G. & Haller, O., 1 Aug ... Enhanced virus resistance of transgenic mice expressing the human MxA protein. Pavlovic, J., Arzet, H. A., Hefti, H. P., Frese ...
The virus grew optimally in the CHSE-214 cell line at 15°C producing a diffuse cytopathic effect; however, juvenile rainbow ... A novel virus, rainbow trout orthomyxovirus (RbtOV), was isolated in 1997 and again in 2000 from commercially-reared rainbow ... Thogotovirus (Thogoto; YP_145794. ), Dhori virus/1313/61 (Dhori; ADF56030. ), RbtOV-1/1997 (RbtOV1; KX882062), and SttOV-1/2014 ... Batts W.N., Winton J.R. Enhanced detection of infectious hematopoietic necrosis virus and other fish viruses by pretreatment of ...
Thogotovirus Thogotovirus* Tick, mosquito, mammal (including human) Dhori virus Batken virus, Bourbon virus, Jos virus ... Influenza virus A Influenza A virus* H1N1, H1N2, H2N2, H3N1, H3N2, H3N8, H5N1, H5N2, H5N3, H5N8, H5N9, H7N1, H7N2, H7N3, H7N4, ... International Committee on Taxonomy of Viruses Index of Viruses - Orthomyxovirus (2006). In: ICTVdB-The Universal Virus ... Jones LD, Nuttall PA (1989). "Non-viraemic transmission of Thogoto virus: influence of time and distance". Trans. R. Soc. Trop ...
Phylogenetic analysis showed that the virus from Thailand grouped with a tilapia virus (family Orthomyxoviridae) from Israel. ... This emerging virus is a threat to tilapia aquaculture in Asia and worldwide. ... several outbreaks of tilapia lake virus infection occurred among tilapia in Thailand. ... and C viruses; infectious salmon anemia virus; Dhori virus; and Thogoto virus (Technical Appendix Table 4) (8-10). Phylogenetic ...
Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as ... indicated by the recent emergence of Bourbon virus in the USA. To successfu … ... Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus. Frese M, Kochs G, Meier-Dieter U, Siebler J, Haller O. ... Research advances on thogoto virus of the family orthomyxoviridae]. Zeng XX, Wang DY, Shu YL. Zeng XX, et al. Bing Du Xue Bao. ...
Next-generation sequencing and phylogenetic analysis identified the virus as a novel member of the genus Thogotovirus. ... However, testing of a specimen for antibodies against Heartland virus by using plaque reduction neutralization indicated the ... Antibodies against Dhori virus in humans have been reported in a similar distribution as those against Thogoto virus (1,6,8,10 ... Two viruses in the genus Thogotovirus (Thogoto and Dhori viruses) are currently known to cause human infection and disease. ...
The gp genes of two thogotoviruses, Thogoto virus and Dhori virus, were inserted into the AcMNPV genome. Both GPs were properly ... The virus genome is 128,587 bp long with a G + C content of 37.9% and 134 predicted ORFs. The virus is an alphabaculovirus ... Fusion of pseudorabies virus glycoproteins to IgG Fc enhances protective immunity against pseudorabies virus. ... The virus presented pyramidal-shaped occlusion bodies (OBs) with singly-embed nucleocapsids and a dose mortality response of ...
The ARC houses reference quantities of reagents and reference viruses that can be distributed to research and commercial ... Thogotovirus. *Araguari virus. *Aransas Bay virus. *Batken virus. *Bourbon virus. *Dhori virus ... Note the virus list is broken down to genus level classification and only contains BSL3 non select agent pathogens. Antigens, ... The following viruses will be added to the collection in the coming months: Mukawa, Kuriyama, Iquitos, and Itaya. ...
Araguari Virus, Aransas Bay Virus, Batken Virus, Dhori Virus, Jos Virus, Thogoto Virus, and Upolu Virus, all of which appear to ... Electron microscopic images of novel Thogotovirus isolate. Filamentous (A) and spherical (B) virus particles with distinct ... and appeared to be closely related to Batken Virus and Dhori Virus, neither of which has ever been isolated in the Western ... Dhori Virus has infected five workers at a Russian lab after accidental exposure in 1987, two of these patients went on to ...
The GP64 superfamily includes the glycoprotein (GP) encoded by members of the Thogotovirus genus of the Orthomyxoviridae. The ... Structural models based on a prototypic class III penetrene, vesicular stomatitis virus glycoprotein (VSV G), were established ... for Thogoto virus (THOV) GP and Autographa california multiple NPV (AcMNPV) GP64 demonstrating feasible cysteine linkages. ... Members of the Baculoviridae encode two types of proteins that mediate virus:cell membrane fusion and penetration into the host ...
Bourbon Virus was isolated and sequenced by the CDC as a novel virus in the genus Thogotovirus in the Orthomyxoviridae family. ... Two closely related viruses in this genus, Thogoto and Dhori, have only yet been found in the eastern hemisphere and cause ... One thought on "Second Ever Case of Bourbon Virus Confirmed in US". * Pingback: Second Ever Case of Bourbon Virus Confirmed in ... Coincidentally, another tick-borne virus, Heartland virus, first discovered in Missouri and Tennessee in 2012, presents with ...
Frese M, Kochs G, Meier-Dieter U, Siebler J, Haller O: Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus ... Shi J, Zhou J, Shah VB, Aiken C, Whitby K: Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus ... Pavlovic J, Zürcher T, Haller O, Staeheli P: Resistance to influenza virus and vesicular stomatitis virus conferred by ... Env HIV-1 viruses in the presence or absence of Bafilomycin A1, which inhibits the entry of pH-dependent viruses [31]. At 6 ...
  • Another virus isolated in 2014 from steelhead trout (also O. mykiss) in Wisconsin, USA, and designated SttOV was found to have eight genome segments with high amino acid sequence identities (89-99%) to the corresponding genes of RbtOV, suggesting these new viruses are isolates of the same virus species and may be more widespread than currently realized. (cdc.gov)
  • thus, specific influenza strain isolates are identified by a standard nomenclature specifying virus type, geographical location where first isolated, sequential number of isolation, year of isolation, and HA and NA subtype. (wikipedia.org)
  • Therefore, we screened a panel of 10 different thogotovirus isolates obtained from various parts of the world for their sensitivity to MxA. (cdc.gov)
  • A total of 56 virus isolates were obtained, 26 from A. gemma, 17 from R. pulchellus, 6 from A. variegatum, and 7 from other species. (cdc.gov)
  • A novel virus, rainbow trout orthomyxovirus (RbtOV), was isolated in 1997 and again in 2000 from commercially-reared rainbow trout (Oncorhynchus mykiss) in Idaho, USA. (cdc.gov)
  • At that time, there were largescale deaths of pilchards caused by a herpes virus and, while testing, Pilchard Orthomyxovirus was also found to be present in these fish. (blogspot.com)
  • As is the case with Pilchard Orthomyxovirus, Infectious Salmon Anaemia virus causes disease in Atlantic salmon, but does not cause disease in herring, brown trout, or other fish species. (blogspot.com)
  • Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. (ajtmh.org)
  • Nucleotide sequences of 7 TiLVs crosis virus, and viral hemorrhagic septicemia virus ( 1 ). (cdc.gov)
  • IFN-α treatment leads to reduced viral protein levels and hinders virus-mediated host shutoff ( 24 ). (asm.org)
  • Representing a major addition to the world literature on the subject, Viral Infections and Global Change explores trends of paramount concern globally, regarding the emergence and reemergence of vector-borne and zoonotic viruses. (wiley.com)
  • Influenza A viruses are further classified, based on the viral surface proteins hemagglutinin (HA or H) and neuraminidase (NA or N). Sixteen H subtypes (or serotypes) and nine N subtypes of influenza A virus have been identified. (wikipedia.org)
  • such viruses include infectious salmon anemia virus, infectious hematopoietic necrosis virus, and viral hemorrhagic septicemia virus ( 1 ). (cdc.gov)
  • Importantly, when introduced into SiAr126, the R328V mutation resulted in complete MxA escape of the recombinant virus, without causing any viral fitness loss. (cdc.gov)
  • The entry of enveloped animal viruses into target cells occurs via fusion of the viral membrane with a cellular membrane. (biomedcentral.com)
  • In general, viral oncogenes are transduced genetic sequences found in the genome of acutely transforming viruses which have cellular homologs (proto-oncogenes) from which they were derived. (rrnursingschool.biz)
  • Evolutionary changes in the virus genome have led in some cases to considerable differences between the products of the viral oncogenes and their cellular homologs, but their relationship can be clearly seen at the genetic level. (rrnursingschool.biz)
  • The third mechanism involved interferons, or signaling proteins released by virus-infected cells to alert neighboring cells to the viral threat. (blogspot.com)
  • A single isolate from Nigeria, Jos virus, showed resistance to the antiviral action of MxA in cell culture and in MxA-transgenic mice, whereas the prototypic Sicilian isolate SiAr126 was fully MxA-sensitive. (cdc.gov)
  • The antiviral effect of IFNs is mediated by several IFN-induced proteins which inhibit the multiplication of viruses by distinct mechanisms (for reviews see references 31 and 37 ). (asm.org)
  • Filamentous (A) and spherical (B) virus particles with distinct surface projection are visible in culture supernatant that was fixed in 2.5% paraformaldehyde. (blogspot.com)
  • Finally, examining supernatants from the cell cultures under the electron microscope revealed virus particles of different shapes, including filaments and spheres. (wikipedia.org)
  • The virus particles show different morphologies, including filamentous and roughly spherical forms, and have projections from the surface. (wikipedia.org)
  • Antibodies to this Virus have also been found in human populations in Europe, Asia and Africa, suggesting that it too may be a more widespread cause of infections than is currently appreciated. (blogspot.com)
  • This article is about the virus family that contains six genera. (wikipedia.org)
  • Some sequences could be assigned into established families and/or genera, while many others were distantly related to known viruses and thus could not be assigned. (virosin.org)
  • Mx proteins form a small family of interferon (IFN)-induced GTPases with potent antiviral activity against various negative-strand RNA viruses. (asm.org)
  • Members of the Baculoviridae encode two types of proteins that mediate virus:cell membrane fusion and penetration into the host cell. (biomedcentral.com)
  • Scientists report it is unclear what role the virus had in the patient's death, but the high level of viremia suggests that this might have contributed to the patient's death. (empr.com)
  • Among TiLVs from Thailand, occurred 1 month after transfer of fish from hatchery to nucleotide and amino acid identities for segment 1 or the grow-out cages in public rivers or reservoirs (1-month putative PB1 gene of the virus were high (99.61%-100%) mortality syndrome). (cdc.gov)
  • Among TiLVs from Thailand, nucleotide and amino acid identities for segment 1 or the putative PB1 gene of the virus were high (99.61%-100%) ( Technical Appendix Table 3). (cdc.gov)
  • This marks the first time a virus in this group has been shown to cause human illness in the United States. (empr.com)
  • IFN also mediates a very potent activity against SFV replication in cell cultures, and the virus is widely used as challenging agent in virus yield reduction assays ( 20 ). (asm.org)
  • In contrast, Dhori virus was not affected by wild-type or mutant MxA protein, indicating substantial differences between these two tick-transmitted orthomyxoviruses. (asm.org)
  • In contrast to negative-strand RNA viruses, which transport their RNA transcriptase within the virion into the cells, the liberated genomic 49S RNA of Semliki Forest virus (SFV) serves directly as mRNA for the synthesis of the RNA polymerase. (asm.org)
  • This emerging virus is a threat to tilapia aquaculture in Asia cessed it for whole-genome sequencing. (cdc.gov)
  • The results demonstrate that the antiviral spectrum of MxA is not restricted to negative-strand RNA viruses but also includes SFV, which contains an RNA genome of positive polarity. (asm.org)
  • Recombinant adeno-associated viruses (rAAVs) are excellent vectors for gene delivery. (bvsalud.org)
  • Next, real-time reverse transcription-polymerase chain reaction was used to confirm that this novel virus originated in the patient's blood sample. (wikipedia.org)
  • Further study is planned to identify more human infections with this novel virus and to assess its potential geographic distribution. (empr.com)
  • Virus was present at high levels in the extracellular space, with occasional particles being observed in the process of endocytosis. (wikipedia.org)
  • But one hazard that is rarely discussed is the dramatic rise in the number and magnitude of tropical virus outbreaks among human populations. (wiley.com)
  • These outbreaks led to identification of a virus affecting tilapia, called tilapia lake virus (TiLV). (cdc.gov)
  • citation needed] The virus was discovered in 2014 by Olga Kosoy, Amy Lambert and colleagues from the Centers for Disease Control and Prevention (CDC) in Fort Collins, Colorado, in a sample of blood from the case patient. (wikipedia.org)
  • The Centers for Disease Control and Prevention (CDC) has reported the discovery of a new virus that may have contributed to the death of a resident in eastern Kansas in late spring of 2014. (empr.com)