A surgical procedure or KERATOPLASTY involving selective stripping and replacement of diseased host DESCEMET MEMBRANE and CORNEAL ENDOTHELIUM with a suitable and healthy donor posterior lamella. The advantage to this procedure is that the normal corneal surface of the recipient is retained, thereby avoiding corneal surface incisions and sutures.
Partial or total replacement of all layers of a central portion of the cornea.
A layer of the cornea. It is the basal lamina of the CORNEAL ENDOTHELIUM (from which it is secreted) separating it from the CORNEAL STROMA. It is a homogeneous structure composed of fine collagenous filaments, and slowly increases in thickness with age.
Disorder caused by loss of endothelium of the central cornea. It is characterized by hyaline endothelial outgrowths on Descemet's membrane, epithelial blisters, reduced vision, and pain.
An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.
Loss of CORNEAL ENDOTHELIUM usually following intraocular surgery (e.g., cataract surgery) or due to FUCHS' ENDOTHELIAL DYSTROPHY; ANGLE-CLOSURE GLAUCOMA; IRITIS; or aging.
Single layer of large flattened cells covering the surface of the cornea.
Partial or total replacement of the CORNEA from one human or animal to another.
Diseases of the cornea.
Centers for storing various parts of the eye for future use.
Presence of an intraocular lens after cataract extraction.
The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes.
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)
Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.
Asymmetries in the topography and refractive index of the corneal surface that affect visual acuity.
Gas lasers with excited dimers (i.e., excimers) as the active medium. The most commonly used are rare gas monohalides (e.g., argon fluoride, xenon chloride). Their principal emission wavelengths are in the ultraviolet range and depend on the monohalide used (e.g., 193 nm for ArF, 308 nm for Xe Cl). These lasers are operated in pulsed and Q-switched modes and used in photoablative decomposition involving actual removal of tissue. (UMDNS, 2005)
Refraction of LIGHT effected by the media of the EYE.
Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.

Safety of DSAEK in patients with previous glaucoma filtering surgery. (1/50)

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Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor Study. (2/50)

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Endothelial keratoplasty: a comparison of complication rates and endothelial survival between precut tissue and surgeon-cut tissue by a single DSAEK surgeon. (3/50)

PURPOSE: Descemet stripping automated endothelial keratoplasty (DSAEK) can be performed with donor tissue prepared with a microkeratome either by the surgeon at the time of surgery or by a technician in the eye bank days before surgery. Are the complications and endothelial survival affected by donor preparation by a surgeon vs a technician? METHODS: A single surgeon at a referral practice performed 225 DSAEK procedures for Fuchs endothelial dystrophy using a similar surgical technique for all cases. Surgeon-cut tissue was used in 49 cases (group 1), and precut tissue was used in 176 cases (group 2). Retrospective analysis was done from a prospectively collected database for donor dislocations, iatrogenic primary graft failure (IPGF), and 6- and 12-month postoperative central endothelial cell density (ECD). RESULTS: There were no dislocations in group 1 and 3 dislocations in group 2 (P = .224). There were no IPGFs in group 1 and one IPGF in group 2. The preoperative donor ECD was 2948 +/- 382 for group 1 and 2728 +/- 269 for group 2. (P < .001). The cell loss at 6 months was 33% +/- 14% for group 1 and 27% +/- 13% for group 2 (P = .01), and cell loss at 12 months was 34% +/- 13% for group 1 and 27% +/- 14% for group 2 (P = .01). Six-month cell loss for 8.0-mm grafts (n=127) was 30% +/- 16% and for larger grafts (n=98) was 27% +/- 12% % (P = .296). CONCLUSIONS: Precut tissue for DSAEK does not increase the risk of the acute complications of graft dislocation or IPGF. Early endothelial cell loss may be less with precut tissue. Larger graft sizes did not result in significantly higher cell counts at 6 months.  (+info)

Effect of incision width on graft survival and endothelial cell loss after Descemet stripping automated endothelial keratoplasty. (4/50)

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Rate and risk factors for cataract formation and extraction after Descemet stripping endothelial keratoplasty. (5/50)

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Clinicopathologic findings in failed descemet stripping automated endothelial keratoplasty. (6/50)

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A comparison of posterior lamellar keratoplasty modalities: DLEK vs. DSEK. (7/50)

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One cornea for two patients: case report. (8/50)

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Descemet Stripping Endothelial Keratoplasty (DSEK) is a type of corneal transplant surgery that involves replacing the damaged endothelium (inner layer) of the cornea with healthy endothelial cells from a donor. In this procedure, the surgeon removes the patient's Descemet's membrane (a thin, clear tissue beneath the endothelium) along with the damaged endothelium. Then, a thin disc of donor tissue, which includes both the endothelium and a small portion of the adjacent corneal stroma, is inserted into the eye and positioned using an air bubble. The new endothelial cells help to pump excess fluid out of the cornea, allowing it to become clear again. DSEK typically results in faster visual recovery and lower rejection rates compared to traditional full-thickness corneal transplantation.

Penetrating keratoplasty (PK) is a type of corneal transplant surgery where the entire thickness of the host's damaged or diseased cornea is removed and replaced with a similar full-thickness portion of a healthy donor's cornea. The procedure aims to restore visual function, alleviate pain, and improve the structural integrity of the eye. It is typically performed for conditions such as severe keratoconus, corneal scarring, or corneal ulcers that cannot be treated with other, less invasive methods. Following the surgery, patients may require extended recovery time and rigorous postoperative care to minimize the risk of complications and ensure optimal visual outcomes.

The Descemet membrane is the thin, transparent basement membrane that is produced by the corneal endothelial cells. It is located between the corneal stroma and the corneal endothelium, which is the innermost layer of the cornea. The Descemet membrane provides structural support for the corneal endothelium and helps to maintain the proper hydration and clarity of the cornea. It is named after the French physician Jean Descemet, who first described it in 1752.

Fuchs' Endothelial Dystrophy is a medical condition that affects the eye's cornea. It is a slowly progressing disorder that causes the endothelium, a thin layer of cells lining the inner surface of the cornea, to deteriorate and eventually fail to function properly. This results in swelling of the cornea, leading to cloudy vision, distorted vision, and sensitivity to light.

The condition is typically inherited and tends to affect both eyes. It is more common in women than in men and usually becomes apparent after the age of 50. There is no cure for Fuchs' Endothelial Dystrophy, but treatments such as corneal transplantation can help improve vision and alleviate symptoms.

Corneal edema is a medical condition characterized by the accumulation of fluid in the cornea, which is the clear, dome-shaped surface at the front of the eye. This buildup of fluid causes the cornea to swell and thicken, resulting in blurry or distorted vision. Corneal edema can be caused by various factors, including eye injuries, certain medications, eye surgeries, and diseases that affect the eye's ability to pump fluids out of the cornea. In some cases, corneal edema may resolve on its own or with treatment, but in severe cases, it may require a corneal transplant.

Corneal endothelial cell loss refers to the decrease in the number of corneal endothelial cells, which is a layer of cells that line the inner surface of the cornea. These cells are essential for maintaining the clarity and health of the cornea, as they help to pump fluids out of the cornea and maintain its transparency.

Corneal endothelial cell loss can occur due to various reasons such as aging, eye trauma, surgery (such as cataract surgery), diseases (such as Fuchs' dystrophy), or inherited conditions. When the number of endothelial cells decreases below a certain threshold, it can lead to corneal swelling, cloudiness, and vision loss.

The rate of corneal endothelial cell loss varies from person to person, but on average, people lose about 0.6% of their endothelial cells per year. Factors such as age, certain medical conditions, and previous eye surgery can increase the rate of cell loss. In some cases, corneal transplantation may be necessary to replace damaged or lost endothelial cells and restore vision.

The endothelium of the cornea is the thin, innermost layer of cells that lines the inner surface of the cornea, which is the clear, dome-shaped structure at the front of the eye. This single layer of specialized cells is essential for maintaining the transparency and proper hydration of the cornea, allowing light to pass through it and focus on the retina.

The endothelial cells are hexagonal in shape and have tight junctions between them, creating a semi-permeable barrier that controls the movement of water and solutes between the corneal stroma (the middle layer of the cornea) and the anterior chamber (the space between the cornea and the iris). The endothelial cells actively pump excess fluid out of the cornea, maintaining a delicate balance of hydration that is critical for corneal clarity.

Damage to or dysfunction of the corneal endothelium can result in corneal edema (swelling), cloudiness, and loss of vision. Factors contributing to endothelial damage include aging, eye trauma, intraocular surgery, and certain diseases such as Fuchs' dystrophy and glaucoma.

Corneal transplantation, also known as keratoplasty, is a surgical procedure in which all or part of a damaged or diseased cornea is replaced with healthy corneal tissue from a deceased donor. The cornea is the clear, dome-shaped surface at the front of the eye that plays an important role in focusing vision. When it becomes cloudy or misshapen due to injury, infection, or inherited conditions, vision can become significantly impaired.

During the procedure, the surgeon carefully removes a circular section of the damaged cornea and replaces it with a similarly sized piece of donor tissue. The new cornea is then stitched into place using very fine sutures that are typically removed several months after surgery.

Corneal transplantation has a high success rate, with more than 90% of procedures resulting in improved vision. However, as with any surgical procedure, there are risks involved, including infection, rejection of the donor tissue, and bleeding. Regular follow-up care is essential to monitor for any signs of complications and ensure proper healing.

Corneal diseases are a group of disorders that affect the cornea, which is the clear, dome-shaped surface at the front of the eye. The cornea plays an important role in focusing vision, and any damage or disease can cause significant visual impairment or loss. Some common types of corneal diseases include:

1. Keratoconus: A progressive disorder in which the cornea thins and bulges outward into a cone shape, causing distorted vision.
2. Fuchs' dystrophy: A genetic disorder that affects the inner layer of the cornea called the endothelium, leading to swelling, cloudiness, and decreased vision.
3. Dry eye syndrome: A condition in which the eyes do not produce enough tears or the tears evaporate too quickly, causing discomfort, redness, and blurred vision.
4. Corneal ulcers: Open sores on the cornea that can be caused by infection, trauma, or other factors.
5. Herpes simplex keratitis: A viral infection of the cornea that can cause recurrent episodes of inflammation, scarring, and vision loss.
6. Corneal dystrophies: Inherited disorders that affect the structure and clarity of the cornea, leading to visual impairment or blindness.
7. Bullous keratopathy: A condition in which the endothelium fails to pump fluid out of the cornea, causing it to swell and form blisters.
8. Corneal trauma: Injury to the cornea caused by foreign objects, chemicals, or other factors that can lead to scarring, infection, and vision loss.

Treatment for corneal diseases varies depending on the specific condition and severity of the disease. Options may include eyedrops, medications, laser surgery, corneal transplantation, or other treatments.

An Eye Bank is an organization that collects, stores, and distributes donated human eyes for corneal transplantation and other ocular medical research purposes. The eye bank's primary function is to ensure the quality of the donated tissue and make it available for those in need of sight-restoring procedures.

The cornea, the clear front part of the eye, can be surgically transplanted from a deceased donor to a recipient with corneal damage or disease, thereby improving or restoring their vision. The eye bank's role includes obtaining consent for donation, retrieving the eyes from the donor, evaluating the tissue for suitability, preserving it properly, and then allocating it to surgeons for transplantation.

Eye banks follow strict medical guidelines and adhere to ethical standards to ensure the safety and quality of the donated tissues. The process involves screening potential donors for infectious diseases and other conditions that may affect the quality or safety of the cornea. Once deemed suitable, the corneas are carefully removed, preserved in specific solutions, and stored until they are needed for transplantation.

In addition to corneal transplants, eye banks also support research and education in ophthalmology by providing human eye tissues for various studies aimed at advancing our understanding of eye diseases and developing new treatments.

Pseudophakia is a medical term that refers to the condition where a person's natural lens in the eye has been replaced with an artificial one. This procedure is typically performed during cataract surgery, where the cloudy, natural lens is removed and replaced with a clear, artificial lens to improve vision. The prefix "pseudo" means false or fake, and "phakia" refers to the natural lens of the eye, hence the term "Pseudophakia" implies a false or artificial lens.

The corneal stroma, also known as the substantia propria, is the thickest layer of the cornea, which is the clear, dome-shaped surface at the front of the eye. The cornea plays a crucial role in focusing vision.

The corneal stroma makes up about 90% of the cornea's thickness and is composed of parallel bundles of collagen fibers that are arranged in regular, repeating patterns. These fibers give the cornea its strength and transparency. The corneal stroma also contains a small number of cells called keratocytes, which produce and maintain the collagen fibers.

Disorders that affect the corneal stroma can cause vision loss or other eye problems. For example, conditions such as keratoconus, in which the cornea becomes thin and bulges outward, can distort vision and make it difficult to see clearly. Other conditions, such as corneal scarring or infection, can also affect the corneal stroma and lead to vision loss or other eye problems.

Visual acuity is a measure of the sharpness or clarity of vision. It is usually tested by reading an eye chart from a specific distance, such as 20 feet (6 meters). The standard eye chart used for this purpose is called the Snellen chart, which contains rows of letters that decrease in size as you read down the chart.

Visual acuity is typically expressed as a fraction, with the numerator representing the testing distance and the denominator indicating the smallest line of type that can be read clearly. For example, if a person can read the line on the eye chart that corresponds to a visual acuity of 20/20, it means they have normal vision at 20 feet. If their visual acuity is 20/40, it means they must be as close as 20 feet to see what someone with normal vision can see at 40 feet.

It's important to note that visual acuity is just one aspect of overall vision and does not necessarily reflect other important factors such as peripheral vision, depth perception, color vision, or contrast sensitivity.

The cornea is the clear, dome-shaped surface at the front of the eye. It plays a crucial role in focusing vision. The cornea protects the eye from harmful particles and microorganisms, and it also serves as a barrier against UV light. Its transparency allows light to pass through and get focused onto the retina. The cornea does not contain blood vessels, so it relies on tears and the fluid inside the eye (aqueous humor) for nutrition and oxygen. Any damage or disease that affects its clarity and shape can significantly impact vision and potentially lead to blindness if left untreated.

Keratoconus is a degenerative non-inflammatory disorder of the eye, primarily affecting the cornea. It is characterized by a progressive thinning and steepening of the central or paracentral cornea, causing it to assume a conical shape. This results in irregular astigmatism, myopia, and scattering of light leading to blurred vision, visual distortions, and sensitivity to glare. The exact cause of keratoconus is unknown, but it may be associated with genetics, eye rubbing, and certain medical conditions. It typically starts in the teenage years and progresses into the third or fourth decade of life. Treatment options include glasses, contact lenses, cross-linking, and corneal transplantation in advanced cases.

Corneal surgery, laser refers to a type of surgical procedure performed on the cornea (the clear, dome-shaped surface at the front of the eye) using a laser. The most common type of laser used in corneal surgery is an excimer laser, which can be used to reshape the cornea and correct refractive errors such as nearsightedness, farsightedness, and astigmatism. This procedure is commonly known as LASIK (Laser-Assisted In Situ Keratomileusis).

Another type of laser corneal surgery is PRK (Photorefractive Keratectomy) which uses a laser to reshape the surface of the cornea. This procedure is typically used for patients who have thin corneas or other conditions that make them ineligible for LASIK.

Additionally, there are other types of laser corneal surgeries such as LASEK (Laser Epithelial Keratomileusis), Epi-LASIK (Epithelial Laser-Assisted Keratomileusis) and SBK (Sub Bowman's Keratomileusis) which are variations of the above procedures.

It is important to note that, as with any surgical procedure, laser corneal surgery has risks and potential complications, including dry eye, infection, and visual symptoms such as glare or halos around lights. It is essential for patients to have a thorough examination and consultation with an ophthalmologist before deciding if laser corneal surgery is the right choice for them.

Corneal wavefront aberration is a measurement of the irregularities in the shape and curvature of the cornea, which can affect the way light enters the eye and is focused on the retina. A wavefront aberration test uses a device to measure the refraction of light as it passes through the cornea and calculates the degree of any distortions or irregularities in the wavefront of the light. This information can be used to guide treatment decisions, such as the prescription for eyeglasses or contact lenses, or the planning of a surgical procedure to correct the aberration.

Corneal wavefront aberrations can be classified into two types: low-order and high-order aberrations. Low-order aberrations include myopia (nearsightedness), hyperopia (farsightedness), and astigmatism, which are common refractive errors that can be easily corrected with glasses or contact lenses. High-order aberrations are more complex irregularities in the wavefront of light that cannot be fully corrected with traditional eyeglasses or contact lenses. These may include coma, trefoil, and spherical aberration, among others.

High-order corneal wavefront aberrations can affect visual quality, causing symptoms such as glare, halos around lights, and decreased contrast sensitivity. They are often associated with conditions that cause changes in the shape of the cornea, such as keratoconus or corneal surgery. In some cases, high-order aberrations can be corrected with specialized contact lenses or refractive surgery procedures such as wavefront-guided LASIK or PRK.

An excimer laser is a type of laser that is used in various medical procedures, particularly in ophthalmology and dermatology. The term "excimer" is derived from "excited dimer," which refers to a short-lived molecule formed when two atoms combine in an excited state.

Excimer lasers emit light at a specific wavelength that is determined by the type of gas used in the laser. In medical applications, excimer lasers typically use noble gases such as argon, krypton, or xenon, combined with halogens such as fluorine or chlorine. The most commonly used excimer laser in medical procedures is the excimer laser that uses a mixture of argon and fluoride gas to produce light at a wavelength of 193 nanometers (nm).

In ophthalmology, excimer lasers are primarily used for refractive surgery, such as LASIK and PRK, to correct vision problems like myopia, hyperopia, and astigmatism. The laser works by vaporizing tiny amounts of tissue from the cornea, reshaping its curvature to improve the way light is focused onto the retina.

In dermatology, excimer lasers are used for various skin conditions, including psoriasis, vitiligo, and atopic dermatitis. The laser works by emitting high-energy ultraviolet (UV) light that selectively targets and destroys the abnormal cells responsible for these conditions while leaving surrounding healthy tissue intact.

Excimer lasers are known for their precision, accuracy, and minimal side effects, making them a popular choice in medical procedures where fine detail and tissue preservation are critical.

Ocular refraction is a medical term that refers to the bending of light as it passes through the optical media of the eye, including the cornea and lens. This process allows the eye to focus light onto the retina, creating a clear image. The refractive power of the eye is determined by the curvature and transparency of these structures.

In a normal eye, light rays are bent or refracted in such a way that they converge at a single point on the retina, producing a sharp and focused image. However, if the curvature of the cornea or lens is too steep or too flat, the light rays may not converge properly, resulting in a refractive error such as myopia (nearsightedness), hyperopia (farsightedness), or astigmatism.

Ocular refraction can be measured using a variety of techniques, including retinoscopy, automated refraction, and subjective refraction. These measurements are used to determine the appropriate prescription for corrective lenses such as eyeglasses or contact lenses. In some cases, ocular refractive errors may be corrected surgically through procedures such as LASIK or PRK.

A tissue donor is an individual who has agreed to allow organs and tissues to be removed from their body after death for the purpose of transplantation to restore the health or save the life of another person. The tissues that can be donated include corneas, heart valves, skin, bone, tendons, ligaments, veins, and cartilage. These tissues can enhance the quality of life for many recipients and are often used in reconstructive surgeries. It is important to note that tissue donation does not interfere with an open casket funeral or other cultural or religious practices related to death and grieving.

Intraocular lens (IOL) implantation is a surgical procedure that involves placing a small artificial lens inside the eye to replace the natural lens that has been removed. This procedure is typically performed during cataract surgery, where the cloudy natural lens is removed and replaced with an IOL to restore clear vision.

During the procedure, a small incision is made in the eye, and the cloudy lens is broken up and removed using ultrasound waves or laser energy. Then, the folded IOL is inserted through the same incision and positioned in the correct place inside the eye. Once in place, the IOL unfolds and is secured into position.

There are several types of IOLs available, including monofocal, multifocal, toric, and accommodating lenses. Monofocal lenses provide clear vision at one distance, while multifocal lenses offer clear vision at multiple distances. Toric lenses correct astigmatism, and accommodating lenses can change shape to focus on objects at different distances.

Overall, intraocular lens implantation is a safe and effective procedure that can help restore clear vision in patients with cataracts or other eye conditions that require the removal of the natural lens.

Corneal opacity refers to a condition in which the cornea, the clear front part of the eye, becomes cloudy or opaque. This can occur due to various reasons such as injury, infection, degenerative changes, or inherited disorders. As a result, light is not properly refracted and vision becomes blurred or distorted. In some cases, corneal opacity can lead to complete loss of vision in the affected eye. Treatment options depend on the underlying cause and may include medication, corneal transplantation, or other surgical procedures.

Graft survival, in medical terms, refers to the success of a transplanted tissue or organ in continuing to function and integrate with the recipient's body over time. It is the opposite of graft rejection, which occurs when the recipient's immune system recognizes the transplanted tissue as foreign and attacks it, leading to its failure.

Graft survival depends on various factors, including the compatibility between the donor and recipient, the type and location of the graft, the use of immunosuppressive drugs to prevent rejection, and the overall health of the recipient. A successful graft survival implies that the transplanted tissue or organ has been accepted by the recipient's body and is functioning properly, providing the necessary physiological support for the recipient's survival and improved quality of life.

"Descemet Stripping With Endothelial Keratoplasty for Treatment of Iridocorneal Endothelial Syndrome". Cornea. 26 (4): 493-497. ... Penetrating karatoplasty and endothelial keratoplasty can be used as treatments for severe cases of ICE. Because glaucoma and ... Iridocorneal endothelial (ICE) syndromes are a spectrum of diseases characterized by slowly progressive abnormalities of the ... The Chandler variant of ICE is characterized by pathology on the inner surface of the cornea leading to abnormal endothelial ...
"Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ... The microkeratome is also used in Descemet's stripping automated endothelial keratoplasty (DSAEK), where it is used to slice a ... endothelial failure". Cochrane Database Syst Rev (3): CD012097. doi:10.1002/14651858.CD012097. "José I. Barraquer, MD". ASCRS ...
The hospital is also one of the few centers in Poland where DSAEK (Descemet Stripping Automated Endothelial Keratoplasty) ...
... deep lamellar endothelial keratoplasty) and DSEK (Descemet's stripping with endothelial keratoplasty). The Devers Eye Institute ... Fernandez, MM; Afshari, NA (2010). "Endothelial Keratoplasty: From DLEK to DMEK". Middle East Afr J Ophthalmol. 17: 5-8. doi: ...
"Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ... The most common types of surgical treatment are Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's ... are formed in the cornea due to endothelial dysfunction. In a healthy cornea, endothelial cells keeps the tissue from excess ... When endothelial cell counts drop too low, the pump starts failing to function and fluid moves anterior into the stroma and ...
"Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ... The endothelial layer is located at the posterior of the cornea. Descemet's membrane, as the basement membrane for the ... Descemet's membrane (or the Descemet membrane) is the basement membrane that lies between the corneal proper substance, also ... The surgeon can scrape away the damaged Descemet membrane and insert/transplant a new membrane harvested from the eye of a ...
"Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ... "Repeat Descemet Membrane Endothelial Keratoplasty after Complicated Primary Descemet Membrane Endothelial Keratoplasty". ... The most common types of surgery for FECD are Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's ... The corneal endothelial cell layer and its basement membrane (Descemet's membrane) act as a barrier to hydration of the corneal ...
"Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ... Descemet's Stripping (Automated) Endothelial Keratoplasty (DSEK/DSAEK) in which the diseased Descemet's membrane is removed and ... "Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor ... Descemet Membrane Endothelial Keratoplasty (DMEK) is the most recent EK technique in which an isolated Descemet's membrane is ...
... and to stain the endothelium in Descemet's stripping endothelial keratoplasty (DSEK). Trypan blue is used in vitreoretinal ... In keratoplasty, trypan blue can be used to stain the posterior stromal fibers during deep lamellar endothelial keratoplasty ( ...
... with endothelium in the patient is removed mechanically by reverse Sinskey hook by controlled stripping on the endothelial side ... Pre Descemet's endothelial keratoplasty (PDEK) is a kind of endothelial keratoplasty, where the pre descemet's layer (PDL) ... "Post operative Spectral Domain Optical Coherence Tomography evaluation of pre-Descemet's endothelial keratoplasty (PDEK) grafts ... "Pre-Descemet's endothelial keratoplasty (PDEK)". Br J Ophthalmol. 98 (9): 1181-5. doi:10.1136/bjophthalmol-2013-304639. PMID ...
... one commonly performed form of endokeratoplasty at present is Descemet's Stripping (Automated) Endothelial Keratoplasty (DSEK [ ... Investigational methods of corneal endothelial surgical replacement include Descemet's Membrane Endothelial Keratoplasty (DMEK ... Endothelial cell loss, if sufficiently severe, can cause endothelial cell density to fall below the threshold level needed to ... in which the donor tissue consists only of Descemet's membrane and endothelium, and corneal endothelial cell replacement ...
... such as Descemet's membrane endothelial keratoplasty (DMEK), Descemet's stripping endothelial keratoplasty (DSEK), and ... This is a combination of Pre-Descemet's endothelial keratoplasty (PDEK) and glued IOL (Fig 8). This combined procedure helps to ... PDEK is a kind of endothelial keratoplasty (corneal or eye transplantation), where the Pre-Descemet's layer (PDL), along with ... "Pre-Descemet's endothelial keratoplasty (PDEK)". Br J Ophthalmol. ncbi.nlm.nih.gov//. 98 (9): 1181-5. doi:10.1136/bjophthalmol- ...
Grafts were clear despite lower than normal endothelial cell counts. To our knowledge, this is the longest running study of ... Long-term results of Descemet stripping automated endothelial keratoplasty Cornea. 2011 Dec;30(12):1414-8. doi: 10.1097/ICO. ... Purpose: To report the long-term outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK). ... or failed penetrating keratoplasty (PKP). Best spectacle-corrected visual acuity (BSCVA), endothelial cell counts (ECC), and ...
Conventional endothelial keratoplasty (EK) entails stripping off the Descemets membrane (DM) and transplantation of the ... we hypothesise that Descemets stripping may be an avoidable intraoperative step in EK for the indications where it is expected ... Four cases where EK was performed without DM stripping are described (table 1). DM removal was deferred in these eyes as there ... However, isolated cases published in the literature support the feasibility of EK without stripping the DM in patients with ...
Refractive changes after descemet stripping endothelial keratoplasty: a simplified mathematical model.  Hwang, Richard Y; ... PURPOSE: To develop a mathematical model that can predict refractive changes after Descemet stripping endothelial keratoplasty ... Browsing by Subject "Descemet Stripping Endothelial Keratoplasty". 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S ...
Outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with failure of ... Outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with failure of ... Outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with failure of ...
Video shows initial portion of host Descemet membrane removal. Following removal the graft is placed in the anterior chamber ... Video shows initial portion of host Descemet membrane removal. Following removal the graft is placed in the anterior chamber ...
Intraocular Pressure Measurements Following Descemet Stripping Endothelial Keratoplasty. Thasarat S. Vajaranant, Marianne O. ... Dive into the research topics of Intraocular Pressure Measurements Following Descemet Stripping Endothelial Keratoplasty. ...
Subconjunctival Air Leakage After Descemets Stripping Automated Endothelial Keratoplasty(DSAEK) in a Post-Trabeculectomy Eye ... Subconjunctival Air Leakage After Descemets Stripping Automated Endothelial Keratoplasty(DSAEK) in a Post-Trabeculectomy Eye ... into a trabeculectomy bleb after Descemets stripping automated endothelial keratoplasty (DSAEK).. Methods: An 89 year-old ... her left eye and previous trabeculectomy with mitomycin C had DSAEK on the patients left eye in order to treat her endothelial ...
... is constantly gaining popularity in the management of endothelial dysfunctions such as bullous keratopathy or Fuchs dystrophy ... Descemets Stripping with Automated Endothelial Keratoplasty (DSAEK) ...
T2 - Phacoemulsification, intraocular lens implantation, and Descemet-stripping automated endothelial keratoplasty. AU - ... and Descemet-stripping automated endothelial keratoplasty. / Hadayer, Amir; Kleinmann, Guy. In: Journal of Cataract and ... and Descemet-stripping automated endothelial keratoplasty, Journal of Cataract and Refractive Surgery, vol. 40, no. 5, pp. 831 ... and Descemet-stripping automated endothelial keratoplasty. In: Journal of Cataract and Refractive Surgery. 2014 ; Vol. 40, No. ...
Histologic evaluation of human posterior lamellar discs for femtosecond laser descemets stripping endothelial keratoplasty.. ... Histologic evaluation of human posterior lamellar discs for femtosecond laser descemets stripping endothelial keratoplasty.. ...
Dive into the research topics of Effect of Graft Thickness on Visual Acuity after Descemet Stripping Endothelial Keratoplasty ... Effect of Graft Thickness on Visual Acuity after Descemet Stripping Endothelial Keratoplasty: A Systematic Review and Meta- ... Effect of Graft Thickness on Visual Acuity after Descemet Stripping Endothelial Keratoplasty: A Systematic Review and Meta- ... Effect of Graft Thickness on Visual Acuity after Descemet Stripping Endothelial Keratoplasty: A Systematic Review and Meta- ...
"Descemet Stripping With Endothelial Keratoplasty for Treatment of Iridocorneal Endothelial Syndrome". Cornea. 26 (4): 493-497. ... Penetrating karatoplasty and endothelial keratoplasty can be used as treatments for severe cases of ICE. Because glaucoma and ... Iridocorneal endothelial (ICE) syndromes are a spectrum of diseases characterized by slowly progressive abnormalities of the ... The Chandler variant of ICE is characterized by pathology on the inner surface of the cornea leading to abnormal endothelial ...
Descemets Stripping Automated Endothelial Keratoplasty (DSAEK)]. ... Endothelial cell loss: Due to possible corneal endothelial cell ... 4.2 Corneal Endothelial Cell Dystrophy DURYSTA is contraindicated in patients with corneal endothelial cell dystrophy (e.g., ... 4.2 Corneal Endothelial Cell Dystrophy 4.3 Prior Corneal Transplantation 4.4 Absent or Ruptured Posterior Lens Capsule 4.5 ... Use caution in patients with limited corneal endothelial cell reserve. (5.1). * Iridocorneal Angle: DURYSTA should be used with ...
Descemets Stripping Endothelial Keratoplasty (DSEK). DSEK removes and replaces diseased tissue from the deepest of the three ... Descemets Membrane Endothelial Keratoplasty (DMEK). The DMEK procedure removes and replaces diseased tissue from the deepest ... Intralase Enabled Keratoplasty (IEK). IEK is a full-thickness transplant approach that utilizes a laser to prepare both the ... Penetrating Keratoplasty (PK) PK is another full-thickness transplant procedure in which the surgeon removes and replaces all ...
The management of penetrating keratoplasty and glaucoma (PKPG) remains controversial mainly because of the high risk of graft ... Glaucoma following penetrating keratoplasty (PKP) is one of the most common causes for irreversible visual loss and the second ... corneal transplant include Descemet membrane endothelial keratoplasty and Descemet stripping automated endothelial keratoplasty ... Comparison of intraocular pressure post penetrating keratoplasty vs Descemets stripping endothelial keratoplasty. Can J ...
Descemet Membrane Endothelial Keratoplasty Versus Descemet Stripping Automated Endothelial Keratoplasty and Penetrating ... Trial Comparing Ultrathin Descemet Stripping Automated Endothelial Keratoplasty with Descemet Membrane Endothelial Keratoplasty ... Descemets stripping endothelial keratoplasty. Curr Opin Ophthalmol. 2007 Jul. 18(4):290-4. [QxMD MEDLINE Link]. ... Descemet-stripping automated endothelial keratoplasty. Cornea. 2006 Sep. 25(8):886-9. [QxMD MEDLINE Link]. ...
Descemets Stripping Endothelial Keratoplasty (DSEK, 2003). Descemets Membrane Endothelial Keratosplaty (DMEK, 2008). Dr. ... Endothelial Keratoplasty (DSEK & DMEK) Share Endothelial keratoplasty (EK) is a cornea transplant technique that is the ... Compared with a traditional full thickness transplant, endothelial keratoplasty provides the following advantages: ... iridocorneal endothelial (ICE) syndrome, or other endothelial disorders. EK selectively replaces only the diseased layer of the ...
Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) are two of ... Descemet membrane endothelial keratoplasty versus descemet stripping automated endothelial keratoplasty. Am J Ophthalmol. 2012 ... Endothelial keratoplasty: fellow eyes comparison of descemet stripping automated endothelial keratoplasty and Descemet membrane ... Graft thickness, graft folds, and aberrations after descemet stripping endothelial keratoplasty for fuchs dystrophy. Am J ...
In the other (lamellar or Descemet stripping and endothelial keratoplasty - DSEK), only the inner layers of the cornea are ... Keratoplasty - discharge; Penetrating keratoplasty - discharge; Lamellar keratoplasty - discharge; DSEK - discharge; DMEK - ...
Descemets stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PKP) corneal transplants ...
DSAEK (Descemets stripping automated endothelial keratoplasty). DSEK (Descemets stripping endothelial keratoplasty). DMEK ( ... Descemets membrane endothelial keratoplasty). Ectropion repair. Electrophysiology. Endocyclophotocoagulation (ECP). Entropion ... Femtosecond laser keratoplasty. Implantable contact lens (ICL). Implantable mini-telescope for age-related macular degeneration ... Fuchs endothelial dystrophy. Glaucoma. Graves disease/thyroid-associated ophthalmopathy. Hemifacial spasm. Herpes-related eye ...
Toxic anterior segment syndrome following a triple Descemets stripping automated endothelial keratoplasty procedure. Case Rep ... On the other hand, Lam et al17 reported no significant differences in the changes of endothelial cell density and central ... These data suggest a dose-dependent toxicity of cefuroxime on human corneal endothelial cells in vitro with a narrow range of ... Comparison of in vitro safety profiles of vancomycin and cefuroxime on human corneal endothelial cells for intracameral use. J ...
I considered performing Descemet-stripping endothelial keratoplasty at this juncture, but I decided to irrigate and aspirate as ... It can also be used for Descemet stripping endothelial keratoplasty with thicknesses below 50 µm. ... Descemet membrane endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology. ... Intraoperative fibrin formation during Descemet membrane endothelial keratoplasty. Am J Ophthalmol Case Rep. 2020;18:100686. ...
Descemets stripping endothelial keratoplasty (DSEK) or Descemets membrane endothelial keratoplasty (DMEK). In both procedures ... Fuchs dystrophy affects the endothelial layer of cells inside the cornea at the front of the eye. Endothelial cells play a ... Less often, penetrating keratoplasty is needed, which replaces the full thickness of the cornea with a donor cornea. The ... Symptoms of Fuchs dystrophy occur when the layer of endothelial cells in the cornea is damaged. When these cells dont work ...
Would you consider combining intervention with Descemet membrane endothelial keratoplasty (DMEK) or Descemet-stripping ... I would not plan on performing Descemet-stripping endothelial keratoplasty simultaneously. The edema should clear after IOL ... I would discuss with the patient the options of simultaneous IOL repositioning and Descemet-stripping automated endothelial ... The two other problems can be managed secondarily if they become clinically significant, with endothelial keratoplasty after ...
Effect of Cornea Preservation Time on Descemet-Stripping Automated Endothelial Keratoplasty Success and Endothelial Cell Loss: ... Host Descemetic Scaffold for Pre-Descemet and Descemet Membrane Endothelial Keratoplasty. Soosan Jacobs. ... Regenerative Therapy for Fuchs Endothelial Corneal Dystrophy: Descemet Membrane Transplantation. Jod S. Mehta, MD, FRCSEd. ... SPS-406 PTK/SMILE/Keratoplasty Techniques. Treating Corneal Edema with Artificial Corneal Endothelial Implant: First Human ...
11/01/2013 - "Persistent corneal opacity after descemet stripping automated endothelial keratoplasty suggesting inert material ... 03/01/2015 - "[Subjective asymptomatic corneal opacity after Descemet membrane endothelial keratoplasty].". ... 01/01/2013 - "Clinical evaluation of Deep Anterior Lamellar Keratoplasty (DALK) for stromal corneal opacities.". 01/01/2013 - " ... 06/01/1985 - "The inadvertent injection of sodium hyaluronate (Healon) just anterior to Descemets membrane during an ...
Loss of corneal endothelial cells (CECs) bears disastrous consequences for the patient, ... Descemets stripping automated endothelial keratoplasty: three-year graft and endothelial cell survival compared with ... Graft rejection following descemet stripping automated endothelial keratoplasty: features, risk factors, and outcomes. Am J ... To ensure that Descemet membrane contains a distinctive microtopography, we first had to remove the endothelial cells from ...
Descemets Membrane Endothelial Keratoplasty) and DSAEK (Descemets Stripping Automated Endothelial Keratoplasty), this aids ... Thin Manual Descemet Stripping Endothelial Keratoplasty (TM-DSEK): The intraoperative OCT clearly showed the Descemet membrane ... Measurements with EnFocus intraoperative OCT during deep anterior lamellar Keratoplasty for Keratoconus (DALK) help to quantify ...
  • Develop a silk fibroin (SF)-based artificial endothelial graft for its use in a rabbit Descemet membrane endothelial keratoplasty (DMEK). (arvojournals.org)
  • Rabbit artificial SF endothelial grafts were transplanted in a DMEK surgery into a rabbit in vivo model. (arvojournals.org)
  • In a rabbit model of DMEK surgery, SF artificial endothelial graft restored the corneal transparency and thickness at 6 week of follow-up. (arvojournals.org)
  • and with mechanical properties that allowed its use in a DMEK surgery, proving its in vivo functionality in a rabbit model of endothelial dysfunction. (arvojournals.org)
  • The Descemet membrane was stripped, and the DMEK graft was inserted through a 2.5-mm clear corneal incision. (crstoday.com)
  • There are two different approaches, depending on how many layers are replaced, Descemet's stripping endothelial keratoplasty (DSEK) or Descemet's membrane endothelial keratoplasty (DMEK). (guidedogs.org.uk)
  • Would you consider combining intervention with Descemet membrane endothelial keratoplasty (DMEK) or Descemet-stripping endothelial keratoplasty? (crstoday.com)
  • In advanced lamellar corneal surgeries such as DMEK (Descemet's Membrane Endothelial Keratoplasty) and DSAEK (Descemet's Stripping Automated Endothelial Keratoplasty), this aids the surgeon in confirming the correct orientation of donor tissue. (leica-microsystems.com)
  • Transplanting the inner layer of the cornea (DMEK) - This surgery, known as Descemet membrane endothelial keratoplasty (DMEK), involves replacing the back layer of the cornea with healthy endothelial cells from a donor. (optometrists.org)
  • In corneal endothelium transplantation, there are 2 techniques: Descemet stripping endothelial keratoplasty (DSEK) and the newest technique, Descemet membrane endothelial keratoplasty (DMEK). (merckmanuals.com)
  • There are multiple types of corneal transplant procedures including Deskemet's Membrane Endothelial Keratoplasty (DMEK) , Penetrating Keratoplasty , and Descemet's Stripping Endothelial Keratoplasty (DSEK) . (capefearcataract.com)
  • DMEK is a procedure that is considered the standard of care for the treatment of disorders such as Fuchs' endothelial dystrophy and Bullous Keratopathy. (capefearcataract.com)
  • Dr. Slade performs cutting-edge, micro-invasive DMEK (Descemet membrane endothelial keratoplasty) transplants as well as DSAEK (Descemet stripping automated endothelial keratoplasty). (visiontexas.com)
  • PURPOSE: To develop a mathematical model that can predict refractive changes after Descemet stripping endothelial keratoplasty (DSEK). (duke.edu)
  • To evaluate the quality of vision (visual acuity and straylight) in patients with Fuchs dystrophy and the improvement in visual quality after Descemet stripping endothelial keratoplasty (DSEK). (iolsafety.com)
  • Purpose To assess the relationship between graft thickness and best-corrected visual acuity (BCVA) after Descemet stripping endothelial keratoplasty (DSEK). (elsevierpure.com)
  • DSEK removes and replaces diseased tissue from the deepest of the three corneal layers, called the endothelium, along with its thin protective coating called the Descemet membrane. (assileye.com)
  • In the other (lamellar or Descemet stripping and endothelial keratoplasty - DSEK), only the inner layers of the cornea are transplanted. (medlineplus.gov)
  • Thin Manual Descemet Stripping Endothelial Keratoplasty (TM-DSEK): The intraoperative OCT clearly showed the Descemet membrane peeling and endothelium. (leica-microsystems.com)
  • Corneal transplant (DSEK)- A partial-thickness corneal transplant , also known as Descemet-stripping endothelial keratoplasty (DSEK), may be recommended by your doctor. (optometrists.org)
  • Instead, DSEK removes the diseased tissue from the back corneal layers, including the endothelium, along with the Descemet membrane, a thin layer of tissue that protects the endothelium from injury and infection. (capefearcataract.com)
  • DSEK is an option for patients with endothelial disease. (capefearcataract.com)
  • Conventional endothelial keratoplasty (EK) entails stripping off the Descemet's membrane (DM) and transplantation of the posterior lamellar graft. (bmj.com)
  • Video shows initial portion of host Descemet membrane removal. (ama-assn.org)
  • Some other common procedures for corneal transplant include Descemet membrane endothelial keratoplasty and Descemet stripping automated endothelial keratoplasty. (medscape.com)
  • The solution is introduced into 500 mL balanced salt solution irrigating fluid, which is then used during or after stripping the host Descemet membrane. (crstoday.com)
  • Because human mesenchymal stem cells are known to be sensitive to their mechanical environments, we investigated the mechanotransductive potential of Descemet membrane-like microtopography (DLT) to differentiate human mesenchymal stem cells into CEC-like cells. (lww.com)
  • Artificial reproduction of Descemet membrane with respect to topography and similar stiffness offers a potential innovative way to bioengineer a functional CEC monolayer from autologous stem cells. (lww.com)
  • Partial thickness corneal transplant, also known as Descemet membrane endothelial keratoplasty, is the most common surgical treatment, in addition to experimental therapies such as Descemet stripping without endothelial keratoplasty. (harvard.edu)
  • First, the endothelium and Descemet's membrane are carefully stripped away through a small incision and then a circular disc is removed from the inner lining of a donor cornea. (adveye2020.com)
  • This procedure replaces a thin layer of tissue inside the eye known as the "Descemet membrane" which helps prevent fluid from building up, thus preventing or limiting edema. (eyesighthawaii.com)
  • Descemet stripping automated endothelial keratoplasty (DSAEK, 46%, n = 5918) was the most commonly performed technique, followed by penetrating keratoplasty (30%, n = 3886) and Descemet membrane endothelial keratoplasty (9%, n = 1838). (lu.se)
  • To report the long-term outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK). (nih.gov)
  • DSAEK was performed for Fuchs corneal dystrophy, pseudophakic or aphakic bullous keratopathy, or failed penetrating keratoplasty (PKP). (nih.gov)
  • To report a case of subconjunctival air leakage from the anterior chamber (AC) into a trabeculectomy bleb after Descemet's stripping automated endothelial keratoplasty (DSAEK). (openophthalmologyjournal.com)
  • An 89 year-old woman with a previous history of primary open angle glaucoma in her left eye and previous trabeculectomy with mitomycin C had DSAEK on the patient's left eye in order to treat her endothelial disease. (openophthalmologyjournal.com)
  • Transient peripheral edema following displaced corneal graft after descemet stripping automated endothelial keratoplasty (DSAEK): case presentation. (unil.ch)
  • Descemet's stripping automated endothelial keratoplasty (DSAEK) appears to have a higher risk of postoperative fungal infections (predominantly Candida) when compared to penetrating keratoplasty (PK). (ophthalmologytimes.com)
  • Fuchs endothelial dystrophy is the most common indication, vision improvement the leading reason, and DSAEK the predominant technique for corneal transplantation. (lu.se)
  • in a corneal transplant technique known as deep anterior lamellar keratoplasty (DALK) the donated corneal tissue replaces the corneal stroma and epithelium only. (merckmanuals.com)
  • Histologic evaluation of human posterior lamellar discs for femtosecond laser descemet's stripping endothelial keratoplasty. (nin.nl)
  • Iridocorneal endothelial (ICE) syndromes are a spectrum of diseases characterized by slowly progressive abnormalities of the corneal endothelium and features including corneal edema, iris distortion, and secondary angle-closure glaucoma. (wikipedia.org)
  • Exposure of mouse corneas to Ultraviolet A (UVA) light induces the progressive disruption of the hexagonal monolayer of corneal endothelium with enlarged and irregular cells preferentially in females recapitulating the clinical presentation of Fuchs endothelial corneal dystrophy patients. (harvard.edu)
  • Fuch's endothelial dystrophy, which is caused by genetic factors that lead to the gradual loss of cells in the endothelium, is a common occurrence, commonly evidenced in those over 50 years of age and more prevalent in women than men. (eyesighthawaii.com)
  • Fuchs' Endothelial Dystrophy is a hereditary abnormality that affects the endothelium, the inner cell layer of the cornea. (visiontexas.com)
  • Penetrating karatoplasty and endothelial keratoplasty can be used as treatments for severe cases of ICE. (wikipedia.org)
  • Conventional corneal transplant is also called penetrating keratoplasty (PKP). (medscape.com)
  • [ 3 ] Thus, the management of penetrating keratoplasty and glaucoma (PKPG) remains controversial mainly because of the high risk for graft failure associated with the treatment. (medscape.com)
  • Changing trends in the indications for penetrating keratoplasty. (medscape.com)
  • TASS has also been reported after phakic intraocular lens implantation, penetrating keratoplasty, and intravitreal injection with bevacizumab. (dovepress.com)
  • Less often, penetrating keratoplasty is needed, which replaces the full thickness of the cornea with a donor cornea. (guidedogs.org.uk)
  • Penetrating keratoplasty (PK) is a full-thickness corneal transplant that is only recommended in rare cases. (optometrists.org)
  • If transplantation involves the full thickness of the cornea (as in penetrating keratoplasty, or PKP), achievement of full visual potential may take up to 18 months because of changing refraction with wound healing and after suture removal. (merckmanuals.com)
  • If other less invasive treatment options do not work, Penetrating Keratoplasty (PK), may be performed as a last resort. (eyemantra.in)
  • I specialise in treating patients with cataract, refractive errors (short-sightedness, long-sightedness, astigmatism, need for reading glasses), keratoconus and corneal dystrophies, such as Fuchs endothelial dystrophy. (spirehealthcare.com)
  • There are many types of corneal disease including keratoconus, Fuchs' endothelial dystrophy, and bullous keratopathy. (visiontexas.com)
  • Symptoms of both Fuchs' endothelial dystrophy and bullous keratopathy include possible glare around lights at night and eventually in bright sunlight. (visiontexas.com)
  • Endothelial keratoplasty (EK) is a cornea transplant technique that is the preferred way to restore vision when the inner cell layer of the cornea stops working properly from Fuchs' dystrophy , bullous keratopathy , iridocorneal endothelial (ICE) syndrome, or other endothelial disorders. (cornea.org)
  • This is a disease of the lining, the endothelial cell layer, of the cornea. (capefearcataract.com)
  • In the procedure, the eye surgeon will replace only the fine endothelial layer of the cornea with an organ donor's cornea. (eyemantra.in)
  • In cases of Fuch's dystrophy or other endothelial dystrophies, there are new techniques where only the back layer of the cornea is replaced, leaving the front portion intact. (visiontexas.com)
  • Hadayer, A & Kleinmann, G 2014, ' Regression of severe corneal neovascularization after a triple procedure: Phacoemulsification, intraocular lens implantation, and Descemet-stripping automated endothelial keratoplasty ', Journal of Cataract and Refractive Surgery , vol. 40, no. 5, pp. 831-832. (tau.ac.il)
  • This procedure is called a KERATOPLASTY and, for many people, it improves vision, lessens pain, and increases their quality of life. (assileye.com)
  • The procedure consists of replacing either the whole cornea or just its endothelial layer with healthy corneal tissue from a donor. (eyesighthawaii.com)
  • A cornea transplant (keratoplasty) is a surgical procedure to substitute part of the cornea with corneal tissue from a donor. (marketresearch.com)
  • Anterior segment optical coherence tomography revealed the SF graft as a fully integrated component in the corneal tissue, displaying a similar corneal thickness and endothelial cell count when compared with its healthy contralateral cornea. (arvojournals.org)
  • Only the inner, damaged layer of the endothelial tissue gets removed. (huffmanandhuffman.com)
  • There are several surgical approaches to cornea transplants (known as corneal keratoplasty). (assileye.com)
  • Best spectacle-corrected visual acuity (BSCVA), endothelial cell counts (ECC), and current graft status were ascertained for the eyes included in the study. (nih.gov)
  • Wacker, K, Bourne, WM & Patel, SV 2016, ' Effect of Graft Thickness on Visual Acuity after Descemet Stripping Endothelial Keratoplasty: A Systematic Review and Meta-Analysis ', American journal of ophthalmology , vol. 163, pp. 18-28. (elsevierpure.com)
  • In patients with Fuchs corneal dystrophy involving the central cornea only, another corneal transplant technique called Descemet stripping only (DSO, not a true transplant because nothing is transplanted) has been used. (merckmanuals.com)
  • San Francisco CA: American Academy of Ophthalmology The Eye M.D. Association Carpel, Emmett F. (2011), "Iridocorneal Endothelial Syndrome", Cornea, Elsevier, pp. 889-899, doi:10.1016/b978-0-323-06387-6.00082-9, ISBN 9780323063876, retrieved 2022-03-02 Alvarado, Jorge A. (1994-12-01). (wikipedia.org)
  • Purpose: The Paul glaucoma implant (PGI, Advanced Ophthalmic Innovations, Singapore, Republic of Singapore) is a recently developed novel non-valved glaucoma drainage device (GDD) designed to effectively reduce the intraocular pressure (IOP) in glaucoma patients with a theoretically reduced risk of postoperative complications such as hypotony, endothelial cell loss, strabismus, and diplopia. (bvsalud.org)
  • Cataract surgery can lead to further loss of endothelial cells, so your ophthalmologist will probably closely examine your eyes if you have Fuchs' dystrophy and are going to have cataract surgery. (guidedogs.org.uk)
  • Graft failure after Descemet stripping automated endothelial keratoplasty is more likely if the donor has diabetes or pseudophakic/aphakic corneal edema and if there were complications during the surgery. (aao.org)
  • Grafts were clear despite lower than normal endothelial cell counts. (nih.gov)
  • However, isolated cases published in the literature support the feasibility of EK without stripping the DM in patients with failed grafts. (bmj.com)
  • Human and rabbit artificial corneal endothelial grafts were developed through the culture of human and rabbit corneal endothelial cells (CECs) on SF films. (arvojournals.org)
  • SF artificial endothelial grafts showed the characteristic endothelial markers: zonula occludens (ZO-1) and Na + /K + ATPase. (arvojournals.org)
  • Predictors of Receiving Keratoplasty for Fuchs' Endothelial Corneal Dystrophy among Medicare Beneficiaries. (medscape.com)
  • It's also known as Fuchs' endothelial corneal dystrophy. (guidedogs.org.uk)
  • Symptoms of Fuchs' dystrophy occur when the layer of endothelial cells in the cornea is damaged. (guidedogs.org.uk)
  • A discovery by Harvard Medical School investigators at Massachusetts Eye and Ear provides new clues that may help improve prevention and treatment of Fuchs endothelial corneal dystrophy (FECD), a genetic eye disease that causes vision loss. (harvard.edu)
  • The endothelial cells of Fuchs' dystrophy, on the other hand, eventually die or fail to function properly, leading to fluid buildup (edema) within the cornea. (optometrists.org)
  • In patients with the condition known as Fuchs' dystrophy, endothelial cells are increasingly lost over time, leading to swelling of the cornea and loss of vision. (capefearcataract.com)
  • 1 2 Based on our observation of favourable outcomes after EK without stripping the DM in patients with no clinical evidence of DM pathology, we hypothesise that Descemet's stripping may be an avoidable intraoperative step in EK for the indications where it is expected to be normal and optically clear. (bmj.com)
  • Histologic analysis showed that the SF artificial endothelial graft was attached and integrated on the surface of the corneal stroma without a significant inflammatory reaction, and rabbit CECs consisted in a monolayer that showed their characteristic markers ZO-1 and Na + /K + ATPase, suggesting proper intercellular junctions and cellular pump function. (arvojournals.org)
  • Loss of corneal endothelial cells (CECs) bears disastrous consequences for the patient, including corneal clouding and blindness. (lww.com)
  • 1 If the number of corneal endothelial cells (CECs) falls below a certain threshold because of traumatic injury, disease, or normal aging processes, functionality of the CE is decreased, and the cornea swells and becomes milky, leading to eventual vision loss. (lww.com)
  • The most advanced treatment for endothelial corneal dysfunction. (bellasee.com)
  • Treatment of endothelial corneal dysfunction by replacing the inner cell layer and a part of the collagen stroma. (bellasee.com)
  • The Chandler variant of ICE is characterized by pathology on the inner surface of the cornea leading to abnormal endothelial pump function. (wikipedia.org)
  • To maintain a clear cornea , the endothelial cells must pump fluid out of the cornea into the anterior chamber. (optometrists.org)
  • Normally, endothelial cells pump out fluid, creating a clear vision and healthy eyes. (eyesighthawaii.com)
  • Herpesvirus DNA has been identified in some patients following keratoplasty, suggesting the possibility that herpes simplex virus may induce the abnormal endotheliazation in the anterior chamber angle and on the surface of the iris. (wikipedia.org)
  • This case presents a few challenges, including repositioning or replacing the IOL and addressing corneal endothelial decompensation and iris damage. (crstoday.com)
  • Due to possible corneal endothelial cell loss, administration of DURYSTA should be limited to a single implant per eye without retreatment. (nih.gov)
  • Figure 1) can prolong graft unscrolling times and contribute to increased endothelial cell loss. (crstoday.com)
  • I would fill the anterior and posterior chambers with OVD using a soft-shell technique to prevent further endothelial cell loss. (crstoday.com)