An acute febrile disease transmitted by the bite of AEDES mosquitoes infected with DENGUE VIRUS. It is self-limiting and characterized by fever, myalgia, headache, and rash. SEVERE DENGUE is a more virulent form of dengue.
A species of the genus FLAVIVIRUS which causes an acute febrile and sometimes hemorrhagic disease in man. Dengue is mosquito-borne and four serotypes are known.
A virulent form of dengue characterized by THROMBOCYTOPENIA and an increase in vascular permeability (grades I and II) and distinguished by a positive pain test (e.g., TOURNIQUET PAIN TEST). When accompanied by SHOCK (grades III and IV), it is called dengue shock syndrome.
Vaccines or candidate vaccines used to prevent infection with DENGUE VIRUS. These include live-attenuated, subunit, DNA, and inactivated vaccines.
A genus of mosquitoes (CULICIDAE) frequently found in tropical and subtropical regions. YELLOW FEVER and DENGUE are two of the diseases that can be transmitted by species of this genus.
Insects that transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.
Immunoglobulins produced in response to VIRAL ANTIGENS.
A family of the order DIPTERA that comprises the mosquitoes. The larval stages are aquatic, and the adults can be recognized by the characteristic WINGS, ANIMAL venation, the scales along the wing veins, and the long proboscis. Many species are of particular medical importance.
Formerly known as Siam, this is a Southeast Asian nation at the center of the Indochina peninsula. Bangkok is the capital city.
I'm sorry for any confusion, but "Nicaragua" is not a medical term and does not have a medical definition. Nicaragua is the largest country in the Central American isthmus, bordering Honduras to the north and Costa Rica to the south. It has both Atlantic and Pacific coasts. The term you might be looking for is "Nicotine," which is a highly addictive stimulant found in tobacco leaves and is used as an ingredient in various products, including cigarettes, smokeless tobacco, and some medications.
Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
I'm sorry for any confusion, but "Vietnam" is not a medical term that can be defined in a medical context; it is a country located in Southeast Asia. If you have any questions related to medical conditions or terminology, I would be happy to help clarify those topics for you.
A genus of FLAVIVIRIDAE containing several subgroups and many species. Most are arboviruses transmitted by mosquitoes or ticks. The type species is YELLOW FEVER VIRUS.
The reduction or regulation of the population of mosquitoes through chemical, biological, or other means.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
An island in the Greater Antilles in the West Indies. Its capital is San Juan. It is a self-governing commonwealth in union with the United States. It was discovered by Columbus in 1493 but no colonization was attempted until 1508. It belonged to Spain until ceded to the United States in 1898. It became a commonwealth with autonomy in internal affairs in 1952. Columbus named the island San Juan for St. John's Day, the Monday he arrived, and the bay Puerto Rico, rich harbor. The island became Puerto Rico officially in 1932. (From Webster's New Geographical Dictionary, 1988, p987 & Room, Brewer's Dictionary of Names, 1992, p436)
Invertebrates or non-human vertebrates which transmit infective organisms from one host to another.
Aspects of health and disease related to travel.
I'm sorry for any confusion, but "Brazil" is not a medical term or concept, it is a country located in South America, known officially as the Federative Republic of Brazil. If you have any questions related to health, medicine, or science, I'd be happy to help answer those!
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Ribonucleic acid that makes up the genetic material of viruses.
The general name for NORTH AMERICA; CENTRAL AMERICA; and SOUTH AMERICA unspecified or combined.
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
I'm sorry for any confusion, but "Sri Lanka" is not a medical term that can be defined in a medical context; it is the name of a country located in South Asia, known for its diverse landscapes and rich biodiversity.
An island in the Greater Antilles in the West Indies, south of Florida. With the adjacent islands it forms the Republic of Cuba. Its capital is Havana. It was discovered by Columbus on his first voyage in 1492 and conquered by Spain in 1511. It has a varied history under Spain, Great Britain, and the United States but has been independent since 1902. The name Cuba is said to be an Indian name of unknown origin but the language that gave the name is extinct, so the etymology is a conjecture. (From Webster's New Geographical Dictionary, 1988, p302 & Room, Brewer's Dictionary of Names, 1992, p132)
Water particles that fall from the ATMOSPHERE.
Substances elaborated by viruses that have antigenic activity.
The collective name for the islands of the central Pacific Ocean, including the Austral Islands, Cook Islands, Easter Island, HAWAII; NEW ZEALAND; Phoenix Islands, PITCAIRN ISLAND; SAMOA; TONGA; Tuamotu Archipelago, Wake Island, and Wallis and Futuna Islands. Polynesians are of the Caucasoid race, but many are of mixed origin. Polynesia is from the Greek poly, many + nesos, island, with reference to the many islands in the group. (From Webster's New Geographical Dictionary, 1988, p966 & Room, Brewer's Dictionary of Names, 1992, p426)
I'm sorry for any confusion, but "Singapore" is not a medical term or concept, it's a country in Southeast Asia. If you have any questions about medical topics, I'd be happy to try and help!
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
An abnormal elevation of body temperature, usually as a result of a pathologic process.

Scientists try new strategy to eradicate dengue fever.(1/2084)

 (+info)

Early immune activation in acute dengue illness is related to development of plasma leakage and disease severity. (2/2084)

T lymphocyte activation and increased cytokine levels have been described in retrospective studies of children presenting with dengue hemorrhagic fever (DHF). Serial plasma samples obtained in a prospective study of Thai children presenting with <72 h of fever were studied. Plasma levels of 80-kDa soluble tumor necrosis factor receptors (sTNFRs) were higher in children who developed DHF than in those with dengue fever (DF) or other nondengue febrile illnesses (OFIs) and were correlated with the degree of subsequent plasma leakage. Soluble CD8 and soluble interleukin-2 receptor levels were also elevated in children with DHF compared with those with DF. Interferon-gamma and sTNFR 60-kDa levels were higher in children with dengue than in those with OFIs. TNF-alpha was detectable more often in DHF than in DF or OFIs (P<.05). These results support the hypothesis that immune activation contributes to the pathogenesis of DHF. Further studies evaluating the predictive value of sTNFR80 for DHF are warranted.  (+info)

Variation in oral susceptibility to dengue type 2 virus of populations of Aedes aegypti from the islands of Tahiti and Moorea, French Polynesia. (3/2084)

Twenty three samples of Aedes aegypti populations from the islands of Tahiti and Moorea (French Polynesia) were tested for their oral susceptibility to dengue type 2 virus. The high infection rates obtained suggest that the artificial feeding protocol used was more efficient than those previously described. Statistical analysis of the results allowed us to define two distinct geographic areas on Tahiti with respect to the susceptibility of Ae. aegypti: the east coast, with homogeneous infection rates, and the west coast, with heterogeneous infection rates. No geographic differences could be demonstrated on Moorea. The possible mechanisms of this phenomenon are discussed in connection with recent findings on the variability of susceptibility of Ae. aegypti to insecticides.  (+info)

Serologic evidence for an epizootic dengue virus infecting toque macaques (Macaca sinica) at Polonnaruwa, Sri Lanka. (4/2084)

Dengue is one of the most rapidly emerging diseases in the tropics. Humans are the principal reservoir of dengue viruses. It is unclear if nonhuman primates also serve as a reservoir of human dengue viruses under certain conditions. In this study, a cross-sectional serologic survey was carried out to characterize the pattern of transmission of a recently identified dengue virus among toque macaques in Sri Lanka. The results indicated that an epizootic dengue virus was active among the macaques. A single epizootic had taken place between October 1986 and February 1987 during which 94% of the macaques within the 3 km2 study site were exposed to the virus. The epizootic was highly focal in nature because macaques living 5 km from the study population were not exposed to the virus. The transmission of dengue viruses among macaques in the wild may have important public health implications.  (+info)

Bacterial lipopolysaccharide inhibits dengue virus infection of primary human monocytes/macrophages by blockade of virus entry via a CD14-dependent mechanism. (5/2084)

Monocytes/macrophages (MO/Mphi) are the major target cells for both dengue virus (DV) and bacterial lipopolysaccharide (LPS), and the aim of this study was to define their interactions. We had found that LPS markedly suppressed DV infection of primary human MO/Mphi when it was added to cultures prior to or together with, but not after, viral adsorption. The inhibitory effect of LPS was direct and specific and was not mediated by LPS-induced secretion of cytokines and chemokines such as tumor necrosis factor alpha, interleukin-1beta (IL-1beta), IL-6, IL-8, IL-12, alpha interferon, MIP-1alpha, and RANTES. In fact, productive DV infection was not blocked but was just postponed by LPS, with a time lag equal to one viral replication cycle. Time course studies demonstrated that LPS was only effective in suppressing DV infection of MO/Mphi that had not been previously exposed to the virus. At various time points after viral adsorption, the level of unbound viruses that remained free in the culture supernatants of LPS-pretreated cultures was much higher than that of untreated controls. These observations suggest that the LPS-induced suppression of DV replication was at the level of virus attachment and/or entry. Blockade of the major LPS receptor, CD14, with monoclonal antibodies MY4 or MoS39 failed to inhibit DV infection but could totally abrogate the inhibitory effect of LPS. Moreover, human serum could significantly enhance the LPS-induced DV suppression in a CD14-dependent manner, indicating that the "binding" of LPS to CD14 was critical for the induction of virus inhibition. Taken together, our results suggest that LPS blocked DV entry into human MO/Mphi via its receptor CD14 and that a CD14-associated cell surface structure may be essential for the initiation of a DV infection.  (+info)

A deviation bar chart for detecting dengue outbreaks in Puerto Rico. (6/2084)

OBJECTIVES: A Centers for Disease Control and Prevention deviation bar chart (Statistical Software for Public Health Surveillance) and laboratory-based surveillance data were evaluated for their utility in detecting dengue outbreaks in Puerto Rico. METHODS: A significant increase in dengue incidence was defined as an excess of suspected cases of more than 2 SDs beyond the mean for all 4-week periods from April through June (the period of lowest seasonal incidence), 1989 through 1993. An outbreak was defined as a cumulative annual rate of reported dengue greater than 3 per 1000 population. RESULTS: Retrospective application of the system to 1994 data showed agreement with previous analyses. In 1995 and 1996, 36.4% and 27.3%, respectively, of municipalities with a significant increase in reports for 2 or more consecutive weeks before the first week of September had an outbreak, compared with 9.0% (in 1995, P = .042) and 6.0% (in 1996, P = .054) of towns without a significant increase. The system showed sensitivity near 40%, specificity near 89%, and accuracy in classifying municipalities near 84%. CONCLUSIONS: This method provides a statistically based, visually striking, specific, and timely signal for dengue control efforts.  (+info)

Effects of dengue fever during pregnancy in French Guiana. (7/2084)

To determine the effects of dengue fever (DF) during pregnancy, pregnant women presenting with a dengue-like syndrome at a hospital in Saint-Laurent du Maroni, French Guiana, from 1 January 1992 to 1 April 1998 were studied. The diagnosis of DF was made by serological tests, virus isolation on AP 61 mosquito cells, and/or reverse transcriptase polymerase chain reaction analysis. Twenty-two women had either probable or confirmed DF. Dengue virus serotype 2 was detected in four cases, and dengue virus serotype 1 was detected in one. Three fetuses died following the onset of the disease, and three cases of prematurity occurred. All infants appeared normal during physical examination, and no neonatal DF was diagnosed. In conclusion, DF in pregnant women did not cause any infant abnormality, but it may have been responsible for fetal death. The rate of fetal death associated with DF (13.6%) was much higher than the mean rate for the gynecology unit at the hospital (1.9%). However, these differences were not significant, and consequently these preliminary results need to be confirmed.  (+info)

Evaluation of the MRL diagnostics dengue fever virus IgM capture ELISA and the PanBio Rapid Immunochromatographic Test for diagnosis of dengue fever in Jamaica. (8/2084)

We evaluated two new commercial dengue diagnostic tests, the MRL Diagnostics Dengue Fever Virus IgM Capture ELISA and the PanBio Rapid Immunochromatographic Test, on serum samples collected during a dengue epidemic in Jamaica. The MRL ELISA method correctly identified 98% (78 of 80) of the samples as dengue positive, while the PanBio test identified 100% (80 of 80). Both tests were 100% (20 samples of 20) specific.  (+info)

Dengue is a mosquito-borne viral infection that is primarily transmitted by the Aedes aegypti and Aedes albopictus species of mosquitoes. It is caused by one of four closely related dengue viruses (DENV 1, DENV 2, DENV 3, or DENV 4). The infection can cause a wide range of symptoms, ranging from mild fever and headache to severe flu-like illness, which is often characterized by the sudden onset of high fever, severe headache, muscle and joint pain, nausea, vomiting, and skin rash. In some cases, dengue can progress to more severe forms, such as dengue hemorrhagic fever or dengue shock syndrome, which can be life-threatening if not treated promptly and appropriately.

Dengue is prevalent in many tropical and subtropical regions around the world, particularly in urban and semi-urban areas with poor sanitation and inadequate mosquito control. There is no specific treatment for dengue, and prevention efforts focus on reducing mosquito populations and avoiding mosquito bites. Vaccines are available in some countries to prevent dengue infection, but they are not widely used due to limitations in their effectiveness and safety.

Dengue virus (DENV) is a single-stranded, positive-sense RNA virus that belongs to the genus Flavivirus in the family Flaviviridae. It is primarily transmitted to humans through the bites of infected female mosquitoes, mainly Aedes aegypti and Aedes albopictus.

The DENV genome contains approximately 11,000 nucleotides and encodes three structural proteins (capsid, pre-membrane/membrane, and envelope) and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). There are four distinct serotypes of DENV (DENV-1, DENV-2, DENV-3, and DENV-4), each of which can cause dengue fever, a mosquito-borne viral disease.

Infection with one serotype provides lifelong immunity against that particular serotype but only temporary and partial protection against the other three serotypes. Subsequent infections with different serotypes can increase the risk of developing severe dengue, such as dengue hemorrhagic fever or dengue shock syndrome, due to antibody-dependent enhancement (ADE) and original antigenic sin phenomena.

DENV is a significant public health concern in tropical and subtropical regions worldwide, with an estimated 390 million annual infections and approximately 100-400 million clinical cases. Preventive measures include vector control strategies to reduce mosquito populations and the development of effective vaccines against all four serotypes.

Severe dengue, also known as dengue hemorrhagic fever, is a severe and potentially fatal complication of dengue virus infection. The World Health Organization (WHO) defines it as follows:

"Dengue hemorrhagic fever is characterized by a high fever (40°C/104°F) that lasts for 2-7 days, with generalized pain and severe headache, bleeding manifestations (e.g., nose or gum bleed, skin rash with bruising, internal bleeding), plasma leakage leading to accumulation of fluid in the lungs or abdomen, and a rapid decrease in platelet count."

Severe dengue can be life-threatening if not diagnosed and treated promptly. It is important to seek medical attention immediately if you suspect you have dengue fever and are experiencing any of the symptoms associated with severe dengue.

Dengue vaccines are designed to protect against dengue fever, a mosquito-borne viral disease that can cause severe flu-like symptoms and potentially life-threatening complications. Dengue is caused by four distinct serotypes of the virus (DENV-1, DENV-2, DENV-3, and DENV-4), and infection with one serotype does not provide immunity against the others.

The first licensed dengue vaccine, Dengvaxia (CYD-TDV), is a chimeric yellow fever-dengue tetravalent vaccine developed by Sanofi Pasteur. It is approved for use in several countries and has demonstrated efficacy against dengue fever caused by all four serotypes in clinical trials. However, the vaccine has raised concerns about the risk of severe disease in individuals who have not been previously exposed to dengue. As a result, it is recommended primarily for people with a documented past dengue infection or living in areas with high dengue prevalence and where the benefits outweigh the risks.

Another dengue vaccine candidate, Takeda's TAK-003 (also known as TDV), is a live attenuated tetravalent dengue vaccine that has shown efficacy against all four serotypes in clinical trials. It was granted approval by the European Medicines Agency (EMA) and several other countries for use in individuals aged 4-16 years old, living in endemic areas.

Research and development of additional dengue vaccine candidates are ongoing to address concerns about safety, efficacy, and accessibility, particularly for at-risk populations in low- and middle-income countries where dengue is most prevalent.

"Aedes" is a genus of mosquitoes that are known to transmit various diseases, including Zika virus, dengue fever, chikungunya, and yellow fever. These mosquitoes are typically found in tropical and subtropical regions around the world. They are distinguished by their black and white striped legs and thorax. Aedes aegypti is the most common species associated with disease transmission, although other species such as Aedes albopictus can also transmit diseases. It's important to note that only female mosquitoes bite and feed on blood, while males feed solely on nectar and plant juices.

Insect vectors are insects that transmit disease-causing pathogens (such as viruses, bacteria, parasites) from one host to another. They do this while feeding on the host's blood or tissues. The insects themselves are not infected by the pathogen but act as mechanical carriers that pass it on during their bite. Examples of diseases spread by insect vectors include malaria (transmitted by mosquitoes), Lyme disease (transmitted by ticks), and plague (transmitted by fleas). Proper prevention measures, such as using insect repellent and reducing standing water where mosquitoes breed, can help reduce the risk of contracting these diseases.

Antibodies, viral are proteins produced by the immune system in response to an infection with a virus. These antibodies are capable of recognizing and binding to specific antigens on the surface of the virus, which helps to neutralize or destroy the virus and prevent its replication. Once produced, these antibodies can provide immunity against future infections with the same virus.

Viral antibodies are typically composed of four polypeptide chains - two heavy chains and two light chains - that are held together by disulfide bonds. The binding site for the antigen is located at the tip of the Y-shaped structure, formed by the variable regions of the heavy and light chains.

There are five classes of antibodies in humans: IgA, IgD, IgE, IgG, and IgM. Each class has a different function and is distributed differently throughout the body. For example, IgG is the most common type of antibody found in the bloodstream and provides long-term immunity against viruses, while IgA is found primarily in mucous membranes and helps to protect against respiratory and gastrointestinal infections.

In addition to their role in the immune response, viral antibodies can also be used as diagnostic tools to detect the presence of a specific virus in a patient's blood or other bodily fluids.

'Culicidae' is the biological family that includes all species of mosquitoes. It consists of three subfamilies: Anophelinae, Culicinae, and Toxorhynchitinae. Mosquitoes are small, midge-like flies that are known for their ability to transmit various diseases to humans and other animals, such as malaria, yellow fever, dengue fever, and Zika virus. The medical importance of Culicidae comes from the fact that only female mosquitoes require blood meals to lay eggs, and during this process, they can transmit pathogens between hosts.

I'm sorry for any confusion, but "Thailand" is not a medical term. It is a country located in Southeast Asia. If you have any questions about medical terms or concepts, I would be happy to help answer those for you!

I'm sorry for any confusion, but "Nicaragua" is not a medical term. It is the largest country in the Central American Isthmus, bordering Honduras to the north and Costa Rica to the south. It has coastlines on both the Caribbean Sea and the North Pacific Ocean.

If you have any medical questions or terms you would like defined, I'd be happy to help!

Antibody-Dependent Enhancement (ADE) is a phenomenon in which the presence of antibodies against a particular virus actually enhances the ability of the virus to infect and replicate within host cells, leading to increased severity of infection. This occurs when the antibodies bind to the virus but do not neutralize it, instead facilitating uptake of the virus into immune cells expressing Fc receptors, such as macrophages. The virus can then use these cells as a site for replication and evasion of the host's immune response. ADE has been observed in various viral infections, including dengue fever and respiratory syncytial virus (RSV) infection. It is a concern in the development of vaccines against these viruses, as non-neutralizing antibodies induced by vaccination could potentially enhance subsequent infection with a heterologous strain of the virus.

Viral nonstructural proteins (NS) are viral proteins that are not part of the virion structure. They play various roles in the viral life cycle, such as replication of the viral genome, transcription, translation regulation, and modulation of the host cell environment to favor virus replication. These proteins are often produced in large quantities during infection and can manipulate or disrupt various cellular pathways to benefit the virus. They may also be involved in evasion of the host's immune response. The specific functions of viral nonstructural proteins vary depending on the type of virus.

A disease outbreak is defined as the occurrence of cases of a disease in excess of what would normally be expected in a given time and place. It may affect a small and localized group or a large number of people spread over a wide area, even internationally. An outbreak may be caused by a new agent, a change in the agent's virulence or host susceptibility, or an increase in the size or density of the host population.

Outbreaks can have significant public health and economic impacts, and require prompt investigation and control measures to prevent further spread of the disease. The investigation typically involves identifying the source of the outbreak, determining the mode of transmission, and implementing measures to interrupt the chain of infection. This may include vaccination, isolation or quarantine, and education of the public about the risks and prevention strategies.

Examples of disease outbreaks include foodborne illnesses linked to contaminated food or water, respiratory infections spread through coughing and sneezing, and mosquito-borne diseases such as Zika virus and West Nile virus. Outbreaks can also occur in healthcare settings, such as hospitals and nursing homes, where vulnerable populations may be at increased risk of infection.

I'm sorry for any confusion, but "Vietnam" is not a medical term. It is the name of a country located in Southeast Asia. If you have any questions about medical conditions or terminology, I would be happy to help clarify those for you.

Flavivirus is a genus of viruses in the family Flaviviridae. They are enveloped, single-stranded, positive-sense RNA viruses that are primarily transmitted by arthropod vectors such as mosquitoes and ticks. Many flaviviruses cause significant disease in humans, including dengue fever, yellow fever, Japanese encephalitis, West Nile fever, and Zika fever. The name "flavivirus" is derived from the Latin word for "yellow," referring to the yellow fever virus, which was one of the first members of this genus to be discovered.

'Mosquito Control' is not a medical term per se, but it is a public health concept that refers to the systematic reduction or elimination of mosquito populations through various methods to prevent or minimize the transmission of mosquito-borne diseases. This multidisciplinary field involves entomologists, ecologists, engineers, and public health professionals working together to manage mosquito habitats, apply insecticides, and educate communities about personal protection measures. By controlling mosquito populations, we can significantly reduce the risk of contracting vector-borne illnesses such as malaria, dengue fever, yellow fever, Zika virus, and West Nile virus, among others.

Serotyping is a laboratory technique used to classify microorganisms, such as bacteria and viruses, based on the specific antigens or proteins present on their surface. It involves treating the microorganism with different types of antibodies and observing which ones bind to its surface. Each distinct set of antigens corresponds to a specific serotype, allowing for precise identification and characterization of the microorganism. This technique is particularly useful in epidemiology, vaccine development, and infection control.

Immunoglobulin M (IgM) is a type of antibody that is primarily found in the blood and lymph fluid. It is the first antibody to be produced in response to an initial exposure to an antigen, making it an important part of the body's primary immune response. IgM antibodies are large molecules that are composed of five basic units, giving them a pentameric structure. They are primarily found on the surface of B cells as membrane-bound immunoglobulins (mlgM), where they function as receptors for antigens. Once an mlgM receptor binds to an antigen, it triggers the activation and differentiation of the B cell into a plasma cell that produces and secretes large amounts of soluble IgM antibodies.

IgM antibodies are particularly effective at agglutination (clumping) and complement activation, which makes them important in the early stages of an immune response to help clear pathogens from the bloodstream. However, they are not as stable or long-lived as other types of antibodies, such as IgG, and their levels tend to decline after the initial immune response has occurred.

In summary, Immunoglobulin M (IgM) is a type of antibody that plays a crucial role in the primary immune response to antigens by agglutination and complement activation. It is primarily found in the blood and lymph fluid, and it is produced by B cells after they are activated by an antigen.

I'm sorry for any confusion, but "Puerto Rico" is not a medical term. It is a territorial possession of the United States, located in the northeastern Caribbean Sea. It includes the main island of Puerto Rico and various smaller islands. If you have any questions about a medical topic, please provide more details so I can try to help answer your question.

A disease vector is a living organism that transmits infectious pathogens from one host to another. These vectors can include mosquitoes, ticks, fleas, and other arthropods that carry viruses, bacteria, parasites, or other disease-causing agents. The vector becomes infected with the pathogen after biting an infected host, and then transmits the infection to another host through its saliva or feces during a subsequent blood meal.

Disease vectors are of particular concern in public health because they can spread diseases rapidly and efficiently, often over large geographic areas. Controlling vector-borne diseases requires a multifaceted approach that includes reducing vector populations, preventing bites, and developing vaccines or treatments for the associated diseases.

I'm sorry for any confusion, but "travel" is not a term that has a specific medical definition. In general, travel refers to the act of moving or journeying from one place to another, often over long distances. However, in a medical context, it might refer to the recommendation that individuals with certain medical conditions or those who are immunocompromised avoid traveling to areas where they may be at increased risk of exposure to infectious diseases. It's always best to check with a healthcare professional for advice related to specific medical situations and travel.

I apologize, but "Brazil" is not a medical term or condition. It is the largest country in both South America and Latin America by land area and population. If you have any questions related to medical terminology or health concerns, please provide more information and I will do my best to help.

An Enzyme-Linked Immunosorbent Assay (ELISA) is a type of analytical biochemistry assay used to detect and quantify the presence of a substance, typically a protein or peptide, in a liquid sample. It takes its name from the enzyme-linked antibodies used in the assay.

In an ELISA, the sample is added to a well containing a surface that has been treated to capture the target substance. If the target substance is present in the sample, it will bind to the surface. Next, an enzyme-linked antibody specific to the target substance is added. This antibody will bind to the captured target substance if it is present. After washing away any unbound material, a substrate for the enzyme is added. If the enzyme is present due to its linkage to the antibody, it will catalyze a reaction that produces a detectable signal, such as a color change or fluorescence. The intensity of this signal is proportional to the amount of target substance present in the sample, allowing for quantification.

ELISAs are widely used in research and clinical settings to detect and measure various substances, including hormones, viruses, and bacteria. They offer high sensitivity, specificity, and reproducibility, making them a reliable choice for many applications.

A viral RNA (ribonucleic acid) is the genetic material found in certain types of viruses, as opposed to viruses that contain DNA (deoxyribonucleic acid). These viruses are known as RNA viruses. The RNA can be single-stranded or double-stranded and can exist as several different forms, such as positive-sense, negative-sense, or ambisense RNA. Upon infecting a host cell, the viral RNA uses the host's cellular machinery to translate the genetic information into proteins, leading to the production of new virus particles and the continuation of the viral life cycle. Examples of human diseases caused by RNA viruses include influenza, COVID-19 (SARS-CoV-2), hepatitis C, and polio.

The "Americas" is a term used to refer to the combined landmasses of North America and South America, which are separated by the Isthmus of Panama. The Americas also include numerous islands in the Caribbean Sea, Atlantic Ocean, and Pacific Ocean. This region is home to a diverse range of cultures, ecosystems, and historical sites. It is named after the Italian explorer Amerigo Vespucci, who was one of the first Europeans to explore and map parts of South America in the late 15th century.

Viral envelope proteins are structural proteins found in the envelope that surrounds many types of viruses. These proteins play a crucial role in the virus's life cycle, including attachment to host cells, fusion with the cell membrane, and entry into the host cell. They are typically made up of glycoproteins and are often responsible for eliciting an immune response in the host organism. The exact structure and function of viral envelope proteins vary between different types of viruses.

I'm sorry for any confusion, but "Sri Lanka" is not a medical term or concept. Sri Lanka is an island country located in the Indian Ocean, south of India. It is known for its diverse landscapes ranging from rainforests and arid plains to highlands and sandy beaches.

If you have any questions related to medicine or healthcare, I would be happy to try and help answer them!

I am not aware of a specific medical definition for "Cuba." Cuba is actually a country, specifically an island nation located in the Caribbean Sea. It is south of Florida and the Bahamas, west of Haiti, and north of Jamaica. The term "Cuba" would not typically be used in a medical context unless it was referring to something or someone that is related to or originates from this country. For example, a "Cuban immigrant" might be mentioned in a medical history, or a patient might have traveled to Cuba for medical treatment. In these cases, the relevant medical information would relate to the individual's personal history or the specific medical care they received, rather than to any inherent qualities of the country itself.

I'm sorry for any confusion, but "rain" is not a medical term. In general, rain refers to water droplets that fall from the sky as part of the Earth's weather cycle. These drops form when moisture in the air condenses and cools, creating clouds which eventually become heavy enough to release the collected water.

If you have any medical concerns or questions, I'd be happy to try and help answer those for you!

An antigen is any substance that can stimulate an immune response, particularly the production of antibodies. Viral antigens are antigens that are found on or produced by viruses. They can be proteins, glycoproteins, or carbohydrates present on the surface or inside the viral particle.

Viral antigens play a crucial role in the immune system's recognition and response to viral infections. When a virus infects a host cell, it may display its antigens on the surface of the infected cell. This allows the immune system to recognize and target the infected cells for destruction, thereby limiting the spread of the virus.

Viral antigens are also important targets for vaccines. Vaccines typically work by introducing a harmless form of a viral antigen to the body, which then stimulates the production of antibodies and memory T-cells that can recognize and respond quickly and effectively to future infections with the actual virus.

It's worth noting that different types of viruses have different antigens, and these antigens can vary between strains of the same virus. This is why there are often different vaccines available for different viral diseases, and why flu vaccines need to be updated every year to account for changes in the circulating influenza virus strains.

I'm sorry for any confusion, but "Polynesia" is not a medical term. It is a geographical region in the Pacific Ocean, consisting of numerous island countries and territories. If you have any questions related to medical terminology or health, I would be happy to try and help answer those for you.

I'm sorry for any confusion, but "Singapore" is not a medical term or concept. It is a sovereign city-state and island country in Southeast Asia. If you have any questions related to medical topics or definitions, I would be happy to try and help answer those for you!

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Hypotension is a medical term that refers to abnormally low blood pressure, usually defined as a systolic blood pressure less than 90 millimeters of mercury (mm Hg) or a diastolic blood pressure less than 60 mm Hg. Blood pressure is the force exerted by the blood against the walls of the blood vessels as the heart pumps blood.

Hypotension can cause symptoms such as dizziness, lightheadedness, weakness, and fainting, especially when standing up suddenly. In severe cases, hypotension can lead to shock, which is a life-threatening condition characterized by multiple organ failure due to inadequate blood flow.

Hypotension can be caused by various factors, including certain medications, medical conditions such as heart disease, endocrine disorders, and dehydration. It is important to seek medical attention if you experience symptoms of hypotension, as it can indicate an underlying health issue that requires treatment.

Fever, also known as pyrexia or febrile response, is a common medical sign characterized by an elevation in core body temperature above the normal range of 36.5-37.5°C (97.7-99.5°F) due to a dysregulation of the body's thermoregulatory system. It is often a response to an infection, inflammation, or other underlying medical conditions, and it serves as a part of the immune system's effort to combat the invading pathogens or to repair damaged tissues.

Fevers can be classified based on their magnitude:

* Low-grade fever: 37.5-38°C (99.5-100.4°F)
* Moderate fever: 38-39°C (100.4-102.2°F)
* High-grade or severe fever: above 39°C (102.2°F)

It is important to note that a single elevated temperature reading does not necessarily indicate the presence of a fever, as body temperature can fluctuate throughout the day and can be influenced by various factors such as physical activity, environmental conditions, and the menstrual cycle in females. The diagnosis of fever typically requires the confirmation of an elevated core body temperature on at least two occasions or a consistently high temperature over a period of time.

While fevers are generally considered beneficial in fighting off infections and promoting recovery, extremely high temperatures or prolonged febrile states may necessitate medical intervention to prevent potential complications such as dehydration, seizures, or damage to vital organs.

The 1997 classification divided dengue into an undifferentiated fever, dengue fever, and dengue hemorrhagic fever. Dengue ... Shock (dengue shock syndrome) and hemorrhage (dengue hemorrhagic fever) occur in less than 5% of all cases of dengue; however, ... "Marking ASEAN Dengue Day". Archived from the original on 17 June 2015. Retrieved 16 June 2015. ACTION AGAINST DENGUE Dengue Day ... Climate change and infectious diseases#Dengue fever "Dengue and severe dengue Fact sheet N°117". WHO. May 2015. Archived from ...
... is a vaccine used to prevent dengue fever in humans. Development of dengue vaccines began in the 1920s, but was ... "Dengue Vaccine Vaccine Information Statement". U.S. Centers for Disease Control and Prevention (CDC). December 2021. Dengue ... "Vacina contra a dengue: aplicação começa nesta semana em clínicas particulares" [Dengue vaccine: administration starts this ... "Takeda's Qdenga (Dengue Tetravalent Vaccine [Live, Attenuated]) Approved in Indonesia for Use Regardless of Prior Dengue ...
Common names for dengue fever include breakbone fever, vomiting and dandy fever; dengue hemorrhagic fever and dengue shock ... dengue shock syndrome). A common problem faced in dengue-endemic regions is when mothers become infected with dengue; after ... Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family ... "Sanofi's dengue vaccine approved in 11 countries". Reuters. 2016. Retrieved 13 August 2017. "Dengue Fever Vaccine Available in ...
... official website Dengue Dengue Dengue! at AllMusic Live session of Dengue Dengue Dengue on RTVE.es (CS1 ... "Dengue Dengue Dengue!". www.redbullmusicacademy.com. Retrieved 2022-08-04. "Hay que conocerlos: Dengue Dengue Dengue". Red Bull ... "Dengue Dengue Dengue: Dimensiones del virus". Peru21 (in Spanish). 2018-04-02. Retrieved 2022-04-13. "Dengue Dengue Dengue ... Dengue Dengue Dengue". Fact Magazine. 2021-01-05. Retrieved 2022-04-14. "Watch Peruvian Audiovisual Duo Dengue Dengue Dengue at ...
"Dengue Fever (2003) album". AllMusic. "Dengue Fever: Artist Biography". AllMusic. Retrieved 1 February 2018. "Dengue Fever: ' ... In 2017, Dengue Fever embarked on their longest-ever American tour as the support act for Tinariwen. In 2018, Dengue Fever ... Dengue Fever (2003) Dengue Fever (EP, 2005) Escape from Dragon House (2005) Sip Off the Mekong (EP, 2006) Venus On Earth (2008 ... "Dengue Fever". AllMusic. Retrieved October 23, 2016. "Psychedelic Cambodian surf band Dengue Fever to visit Bay". San Francisco ...
Dengue Fever Hits Paraguay Reuters, "Dengue Fever Hits Paraguay", New York Times" (March 4, 2007)] "Dengue Fever Outbreak ... Significant outbreaks of dengue fever tend to occur every five or six months. The cyclical rise and fall in numbers of dengue ... Epidemic dengue has become more common since the 1980s. By the late 1990s, dengue was the most important mosquito-borne disease ... "Dengue in the Americas: 2 million cases and counting, deaths top 1,000". 2015-11-08. "Dengue in Asia: Updated case counts for ...
Dengue fever may also refer to: Dengue virus, the virus that causes dengue fever Dengue Fever (band) Dengue fever outbreaks ... Dengue fever is an endemic viral infectious disease. ... page lists articles associated with the title Dengue fever. If ...
"World Community Grid - Research - Discovering Dengue Drugs - Together". World Community Grid. "Discovering Dengue Drugs - ... Discovering Dengue Drugs - Together (DDDT) was a World Community Grid project launched in 2007 sponsored by scientists at the ... "Discovering Dengue Drugs Together project slowed down because of hurricane". World Community Grid ("Known Issues" forum posting ... Drug candidates that make it through Phase 2 were lab-tested, and in 2014, a novel small-molecule inhibitor of dengue virus ...
1 of 20 individuals who become ill with dengue will develop severe dengue. Severe dengue can lead to life-threatening condition ... The 2009 Bolivian dengue fever epidemic was an epidemic of dengue fever which struck Bolivia in early 2009, escalating into a ... Dengue fever at the BBC Dengue fever at the Centers for Disease Control and Prevention Pan American Health Organisation ( ... There is no specific treatment for dengue, other than managing the symptoms. The best way to address dengue is to disrupt the ...
... www.dengue.gov.sg/ - official website for Campaign Against Dengue Dengue Hotspots - Ministry of Health Dengue Prevention ... "Dengue cases down for 4th week in a row". TODAY. 29 July 2013. Ng, Keng Gene (14 October 2020). "28 people have died of dengue ... In the 2005 dengue outbreak in Singapore, a significant rise in the number of dengue fever cases was reported in Singapore, ... Mosquito control 2006 dengue outbreak in Pakistan 2013 dengue outbreak in Singapore Koh, Benjamin K. W.; Ng, Lee Ching; Kita, ...
2006 dengue outbreak in Pakistan Dengue fever More dengue, chikungunya cases reported, NDTV Web Version, Accessed 9 October ... In the 2006 dengue outbreak in India, cases of dengue fever were reported first from New Delhi in early September and by the ... Highest no of dengue deaths in Delhi today, Hindustan Times. Accessed: October 13 AIIMS student dies of dengue in Delhi, Daily ... Nationwide data on the dengue outbreak, released by the Ministry of Health On 13 October 2006, six persons died due to dengue ...
The 2019 dengue outbreak in Bangladesh is a nationwide occurrence of dengue fever in Bangladesh that began primarily in April ... In August 2019, Bangladesh Governments withdraws all tariffs on dengue test kits imports. Dengue fever was first observed in ... 2023 dengue outbreak in Bangladesh ১১ মাস পর ডেঙ্গুহীন হাসপাতাল. Bdnews24.com (in Bengali). Dhaka. 2020-02-28. Retrieved 2020- ... According to official source, roughly 71 more people are being infected in dengue fever every hour. Dhaka is the worst-hit city ...
In Bangladesh's ongoing 2023 dengue epidemic season, the country has been witnessing the deadliest outbreak of dengue fever ... Dengue Press Release - 11/10/2023, Health Emergency Operation Centre and Control Room, MIS, Directorate General of Health ... 2019 dengue outbreak in Bangladesh List of epidemics Currently hospitalized Discharged from hospital Paul, Ruma (5 August 2023 ... "ডেঙ্গুতে এবছর মৃত্যু আগের সব হিসাব ছাড়াল" [Deaths for dengue this year crosses all past records]. Bdnews24.com (in Bengali). 3 ...
In the 2015 dengue outbreak in Taiwan, a significant rise in the number of dengue fever cases was reported in Tainan City, ... Tainan City Government Dengue Epidemic Bulletin Department of Health of Tainan's Dengue Epidemic Bulletin v t e (Articles with ... "CECC for Dengue Outbreak announces new deaths associated with dengue and urges public to reinforce cleaning and emptying of ... The average number of days between onset and death is 6.2." The same press release as above states: "Currently, 44 dengue ...
The dengue pandemic in Sri Lanka is part of the tropical disease dengue fever pandemic. Dengue fever is caused by Dengue virus ... From 1989 onward, dengue fever has become endemic in Sri Lanka. Dengue outbreaks started to emerge in Sri Lanka in the 1960s, ... In 1990 dengue cases rose 1,350 of 54 deaths.[clarification needed] In the early 1990s, annual dengue cases were reported as ... Historical Account of Dengue Haemorrhagic Fever in Sri Lanka (1997). "Historical of Dengue Fever in Sri Lanka" (PDF). World ...
2006 dengue outbreak in India 2011 dengue outbreak in Pakistan Mosquito control Ghani, MH (May-August 2008). "Dengue virus ... The 2006 dengue outbreak in Pakistan was at the time the worst on record. There were 1931 lab-confirmed cases, and 41 confirmed ... Since 2006, studies indicate that dengue fever is on the rise in Pakistan. It is noted throughout the year, peaking at post- ... 6 (37): 1. Rasheed, SB (January 2013). "A review of dengue as an emerging disease in Pakistan". Public Health. 127 (1): 11-17. ...
In the 2017 dengue outbreak in Peshawar, Pakistan, hundreds of incidents of dengue fever were reported in Peshawar in mid-2017 ... "Dengue experts to stay in Peshawar". www.dawn.com. 21 August 2017. "Punjab dengue experts leave for Peshawar". reliefweb.int. " ... 2011 dengue outbreak in Pakistan "Emergency meeting called over Peshawar dengue outbreak". www.dawn.com. 19 August 2017. " ... "Dengue continues to ring alarm bells in Peshawar". pakobserver.net. Archived from the original on 2017-08-24. Retrieved 2017-08 ...
2011 dengue outbreak in Pakistan 2017 dengue outbreak in Peshawar "WHO EMRO , Outbreak update - Dengue in Pakistan, 1 December ... "Dengue cases surpass all-time record in the country". Dawn. October 15, 2019. "Official says deadly dengue outbreak in Pakistan ... "PM Imran takes strict notice of dengue outbreak". Dunya News. 1 October 2019. "PHC summons health secy over dengue outbreak". ... "Record-high 44,000 dengue cases reported in Pakistan". www.aljazeera.com. Retrieved 2020-08-18. v t e (Articles with short ...
"Vicious dengue continues taking lives." The News.com Accessed 12 May 2013. Deadliest day in Lahore as 15 more die of dengue ... 2017 dengue outbreak in Peshawar Pakistan portal "Why Pakistan Is Having The Dengue Epidemic Every Summer?" Medicalopedia 19 ... "Seven more succumb to dengue in city." Dawn.com Accessed 12 May 2013. "Pakistan hit by Dengue fever outbreak." Archived 2011-12 ... A special tribunal for Dengue fever was empanelled. The chairman of the Dengue Emergency Response Committee was Khawaja Saad ...
2019 dengue outbreak in Bangladesh 2019 dengue outbreak in Pakistan "Philippines declares epidemic after dengue fever kills ... revealed the appearance of autochthonous dengue in Europe along with the increase in imported dengue and dengue severity. ... "Casos de dengue". OPS/OMS. Archived from the original on 2020-03-26. Retrieved 2020-03-26. "Casos y muertes dengue grave". OPS/ ... The 2019-2020 dengue fever epidemic was an epidemic of the infectious disease dengue fever in several countries of Southeast ...
Dengue fever outbreaks (worldwide) Ng, Jun Sen (11 February 2020). "Dengue cases at four-year high". today. the dengue outbreak ... In the 2013 dengue outbreak in Singapore, a significant rise in the number of dengue fever cases was reported in Singapore. The ... "Dengue cases down for 4th week in a row". TODAY. 29 July 2013. "Singapore's dengue cases reach a record 22,403, surpassing 2013 ... "Number of dengue cases weekly hits 5-year high". today. 16 February 2013. "Number of dengue cases hits new high". today. 16 ...
In the 2020 dengue outbreak in Singapore, a record-breaking number of dengue fever cases was reported in Singapore. This was ... "Dengue Cases Expected To Exceed Last Year's 16,000 Cases Unless All Stakeholders Take Immediate Concerted Action Against Dengue ... The year ended with a total of 35,315 dengue fever cases, including 54 instances of dengue haemorrhagic fever, a more severe ... "Dengue surveillance data, Jan - Mar 2020" (PDF). National Environment Agency. "Dengue surveillance data, Apr - Jun 2020" (PDF ...
The Cook Islands Dengue Fever Outbreak refers to the Dengue fever outbreak in the Cook Islands beginning sometime in January ... "Dengue update 27 February 2019 - Cook Islands". ReliefWeb. Retrieved 20 May 2019. "Cook Islands declare dengue outbreak in ... "Dengue-1 Outbreak in the Cook Islands: Situation Report 10: ending 12 March 2020 - Reporting Date: 13 March 2020". ReliefWeb. ... This was relatively new, as the last dengue fever outbreak was in 2009; this specific serotype of DENV-1 in 2007. Initial cases ...
In the 2017 dengue epidemic in Sri Lanka, a rise in the number of dengue fever cases was reported on the island country of Sri ... "Dengue and severe dengue". www.who.int. Retrieved 2022-10-28. Guha-Sapir, Debarati; van Panhuis, Willem Gijsbert (December 2009 ... Dengue treatment strained national economic resources costing Sri Lanka US $12.7 million (LKR 1.938 billion). Today dengue ... Dengue fever - Sri Lanka". WHO. Archived from the original on July 21, 2017. Retrieved 2020-11-27. "Sri Lanka: Dengue Outbreak ...
NSAIDs may increase the risk of bleeding in patients with Dengue fever For this reason, NSAIDs are only available with a ... "Dengue". United States Centers for Disease Control and Prevention. 28 March 2016. Retrieved 27 April 2018. Use acetaminophen. ...
Therefore, its use as a diagnostic test for dengue is questioned as people who have a negative test may still have dengue. It ... 2011). "Predictive diagnostic value of the tourniquet test for the diagnosis of dengue infection in adults". Trop Med Int ... 2006). "Repeated tourniquet testing as a diagnostic tool in dengue infection". Med J Malaysia. 61: 22-7. (Articles with short ... Hess test WHO (2009). Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control (PDF). ISBN 978-92-4-154787-1. " ...
"Symptoms and Treatment , Dengue , CDC". Centers for Disease Control and Prevention. 2019-09-26. Retrieved 2019-11-06. "About ... Vaccines are not available against the viruses responsible for HIV/AIDS, dengue, and chikungunya. Treatment of viral infections ... dengue fever, Hepatitis A, Hepatitis C, rubella, and yellow fever V: (−)ssRNA viruses (− strand or antisense) RNA (e.g., ...
He also highlighted the importance of dengue, a related mosquito-borne virus, as a cause of neurological disease. He works on ... Dengue. In: Nath A, Berger J, editors. Clinical Neurovirology. Marcel Decker, New York NY. pp. 469-516. "Scientist wins pounds ... "Neurological manifestations of dengue infection". The Lancet. 355 (9209): 1053-1059. doi:10.1016/S0140-6736(00)02036-5. PMID ...
Wilder-Smith A, Ooi EE, Horstick O, Wills B (January 2019). "Dengue". Lancet. 393 (10169): 350-363. doi:10.1016/s0140-6736(18) ...
Halstead, Scott B. (2009-03-31). Dengue. Imperial College Press. ISBN 9781848162297. Retrieved 2012-05-20. Jules Dubos, René; ...
... how dengue spreads, how to prevent dengue and mosquito bites ... Dengue. What is Dengue?. Dengue viruses are spread to people ... Dengue Vaccine. A dengue vaccine is approved for use in children aged 9 to 16 years with laboratory-confirmed previous dengue ... Dengue Vaccineplus icon*For Healthcare Providers: A Dengue Vaccine Can Protect Your Patientsplus icon*Vaccine Eligibility & ... For Parents: A Safe and Effective Vaccine to Prevent Dengue Is Now Availableplus icon*Who Can Get a Dengue Vaccine & Whenplus ...
Classical dengue with rash after appropriate incubation in first and subsequent volunteers and Ae aegypti transmission.** ...
This report details the identification of the first locally acquired human dengue virus infection in Maricopa County, Arizona. ... First Pill for Dengue Shows Promise in Human Challenge Trial * Dengue Will Take Off in Southern Europe, US, Africa This ... Immunization Against Dengue: The Accumulated Clinical Trial Data 0.25 CME Credits Clinical Review ... On November 7, 2022, dengue virus (DENV), which is not endemic in the continental United States,[1] was identified in a ...
... dengue virus 1 (DEN-1), dengue virus 2 (DEN-2), dengue virus 3 (DEN-3), and dengue virus 4 (DEN-4). The Aedes aegypti mosquito ... Dengue fever is a mosquito-borne viral disease caused by 1 of 4 antigenically distinct dengue flaviviruses: ... dengue virus 1 (DEN-1), dengue virus 2 (DEN-2), dengue virus 3 (DEN-3), and dengue virus 4 (DEN-4). The Aedes aegypti mosquito ... outbreaks of dengue fever, dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS) have increased in frequency and ...
World Distribution of Dengue. Aedes Aegypti Distribution in the Americas. INTRODUCTION. Dengue and dengue hemorrhagic fever ( ... Why dengue hemorrhagic fever in Cuba? * Individual risk factors for dengue hemorrhagic fever/dengue shock syndrome. Trans R Soc ... Dengue and Dengue Hemorrhagic Fever Dengue Branch and the Division of Vector Borne Infectious Diseases, Centers for Disease ... Dengue and dengue hemorrhagic fever in the Americas. In: Thongcharoen P, ed. Dengue hemorrhagic fever. WHO Monograph. New Delhi ...
... dengue - Sharing our stories on preparing for and responding to public health events ... Tags dengue, disease, EIS, fever, Marshall Islands, mosquito Dengue: The Key West Tour. I often get asked about mosquito-borne ... Tags CDC, dengue, fever, Florida, key west, mosquito, Texas The Reality of Outbreak Investigations: Dengue in Angola. By Tyler ... Tags africa, dengue, mosquitoes Coming (Back) to America? What 2013 Can Teach Us About Dengue in the United States. By Tyler ...
Dengue fever is usually mild but can become serious. Learn more. ... dengue fever test checks a blood sample for signs of the dengue ... Why do I need a dengue fever test?. You may need to be tested for the dengue virus if you have symptoms of dengue fever and ... Have already had dengue fever. The vaccine helps protect against future dengue infections or from getting severe dengue disease ... Some people who get sick with dengue will develop severe dengue disease. Severe dengue can cause internal bleeding and shock, ...
Dengue. Click to expandDengue is a mosquito-borne viral disease that is transmitted between humans by Aedes mosquitoes. The ... Reports of dengue and severe dengue epidemics in the Region started in 1998 and have increased in frequency and spread ever ... Serological evidence of circulation of dengue fever has also been reported from Jordan. All the 4 serotypes of dengue virus ... Once infection has occurred, there is no specific treatment for dengue fever, although for severe dengue early detection and ...
Describe current dengue epidemiology and the populations who are at greatest risk for dengue and severe dengue in the United ... dengue, dengue with warning signs, severe dengue) based on a patients clinical and laboratory findings. ... What Clinicians Need to Know about Dengue in the United States. *Evaluating and Supporting Patients Presenting with ... During this COCA Call, presenters will discuss the current global and domestic dengue epidemiology and its relevance for ...
The 1997 classification divided dengue into an undifferentiated fever, dengue fever, and dengue hemorrhagic fever. Dengue ... Shock (dengue shock syndrome) and hemorrhage (dengue hemorrhagic fever) occur in less than 5% of all cases of dengue; however, ... "Marking ASEAN Dengue Day". Archived from the original on 17 June 2015. Retrieved 16 June 2015. ACTION AGAINST DENGUE Dengue Day ... Climate change and infectious diseases#Dengue fever "Dengue and severe dengue Fact sheet N°117". WHO. May 2015. Archived from ...
Almost half of the worlds population, about 4 billion people, live in areas with a risk of dengue. Dengue is often a leading ... Dengue viruses are spread to people through the bite of an infected Aedes species mosquito. ... Dengue Vaccineplus icon*For Healthcare Providers: A Dengue Vaccine Can Protect Your Patientsplus icon*Vaccine Eligibility & ... About Dengue. *Dengue viruses are spread to people through the bite of an infected Aedes species (Ae. aegypti or Ae. albopictus ...
Although dengue in Timor-Leste is not unexpected, the significant daily increase in the number of dengue cases and the rate of ... In previous outbreaks between 2005 and 2012, two co-circulating serotypes, dengue virus 1 (DENV-1) and dengue virus 3 (DENV-3 ... There is no specific treatment for dengue. Early recognition of dengue virus infection and appropriate clinical management can ... Dengue is a mosquito-borne viral infection that is caused by four DENV serotypes (DENV 1, DENV 2, DENV 3 and DENV 4). Aedes ...
Dengue fever is an infectious disease caused by dengue virus that comes from the bite of Aedes aegypti mosquito. Its primary ... How many people die from dengue fever? How many people get dengue fever every year? What is fluid leakage in dengue? Is dengue ... Dengue Fever. Dengue fever is an infectious disease caused by dengue virus that comes from the bite of Aedes aegypti mosquito. ... When the dengue patient is in at the stage 4 what are symptoms? Which animals have dengue fever? How can dengue fever be ...
... "vacunas contra el dengue" or "dengue vaccines" or "Dengue Fever" OR "Fiebre Dengue" OR "Febre da Dengue" OR "fiebre dengue" OR ... Dengue; Chikungunya. Resultado da busca. Dengue e Chikungunya Dengue y Chikungunya Dengue and Chikungunya prevention. Filtros. ... Chikungunya OR Dengue or "Dengue Hemorrhagic Fever" or "Febre Hemorragica da Dengue" or "dengue hemorrágica" or "Fiebre ... Página inicial > Prevenção de Dengue e Chikungunya. Prevenção de Dengue e Chikungunya Revisado. Sobre a busca. Responsible. ...
ACIP analysis of the Dengvaxia Dengue Vaccine for persons 9-16 years of age with laboratory-confirmed previous dengue infection ... No dengue vaccination. Outcomes. Protection against virologically confirmed dengue, severe dengue, and hospitalization for ... severe dengue, and hospitalization among children ages 9-16 yrs with confirmed previous dengue infection, CYD-TDV Dengue ... Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy.. N Engl J. Med; 2019. ...
Dengue fever is a mosquito-borne infection that causes severe flu-like symptoms. It can be fatal. There is no cure, but there ... Symptoms range of dengue fever from mild to severe. Severe symptoms can indicate. dengue shock syndrome (DSS) and dengue ... Dengue and severe dengue. (2022).. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue. ... have had dengue in the past. *live in areas where dengue is common, including Puerto Rico, American Samoa, Guam, and the U.S. ...
The anti-dengue drive initiated by the district administration is in full swing under which surveillance is being carried out ... 120 Johar Town on Monday and inspected anti-dengue arrangements and instructed house owners about dengue preventive measures. ... LAHORE:The anti-dengue drive initiated by the district administration is in full swing under which surveillance is being ... The deputy commissioner visited houses of three dengue patients in the area and reviewed the case response in the houses and ...
KUALA LUMPUR: Those caught repeatedly breeding Aedes mosquito at construction sites will be imprisoned, the Health Ministry warned.
... is warning that this years seasonal outbreak of dengue may be more severe than usual, following three early deaths in 2022 -- ... "Last year only six people died because of dengue while this year three dengue deaths have been reported in just the first three ... Even though most patients who catch dengue are children and adolescents, most dengue-related deaths are among the elderly, ... While most people focus on the prevention of Covid-19, the risk of catching dengue fever tends to be overlooked, he said. ...
... and dengue hemorrhagic fever (DHF) is that the latter is a severe form of dengue that occurs in a person with dengue infection. ... Dengue Fever. Dengue fever is contracted from the bite of a striped Aedes aegypti mosquito. Symptoms and signs of dengue ... The major difference between dengue fever (DF) and dengue hemorrhagic fever (DHF) is that the latter is a severe form of dengue ... What Should I Know About Dengue Fever?. Dengue fever, also called breakbone fever, is an illness caused by the dengue virus. It ...
... www.kff.org/news-summary/southeast-asia-experiencing-serious-dengue-outbreak/ ... Southeast Asia Experiencing Serious Dengue Outbreak. Southeast Asia Experiencing Serious Dengue Outbreak. Published: Sep 29, ...
Index cluster study of dengue virus infection in Nicaragua. Am J Trop Med Hyg. 2010;83(3):683-9. doi:10.4269/ajtmh.2010.10-0023 ... Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Sci ... Genetic diversity and lineage dynamic of dengue virus serotype 1 (DENV-1) in Cambodia. Infect Genet Evol. 2013;15:59-68. doi: ... Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission. PLoS ...
Dengue infections triple current estimates. ScienceHealthResearch. The global burden of dengue infection is more than triple ... Dengue, also known as breakbone fever, is a viral infection that is transmitted between humans by mosquitoes. In some people ... Until now, little was known about the current distribution of the risk of dengue virus infection and its public health burden ... The team estimate that there are 390 million dengue infections across the globe each year, of which 96 million reach any level ...
Dengue vaccine could increase or worsen dengue in some settings Researchers say health officials must be careful about where ... Dengue can cause a high fever, severe headaches, severe pain behind the eyes, rash and joint, muscle or bone pain. Dengue ... Dengue vaccine could increase or worsen dengue in some settings. Johns Hopkins Bloomberg School of Public Health ... In those who have not yet been infected with dengue, the vaccine causes the immune system to recognize that a first dengue ...
... of the dengue reported cases worldwide. This review addresses vector distribution, dengue outbreaks, circulating serotypes and ... The incidence of dengue in Brazil has been frequently high, and the number of cases in the country has at some point in time ... It is caused by any of four ,i,Dengue virus,/i, types or serotypes (DENV-1 to DENV-4) and is transmitted by mosquitoes from the ... genus ,i,Aedes,/i,. Ecological changes have favored the geographic expansion of the vector and, since the dengue pandemic in ...
Archives for Dengue Fever. Learning in new languages - Dengue Fever: From Cambodia to the Triple Door. February 6, 2015. By ... Filed Under: Arts & Entertainment, Features, Profiles Tagged With: 2015, Apsara Awards, Brazil, Chhom Nimol Cambodian, Dengue ... By Andrew Hamlin Northwest Asian Weekly Dengue Fever, a band well known for combining Cambodian pop with Western-style pop and ...
Dengue Fever News and Research. RSS Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms ... Study sheds light on the burden of dengue in Bangladesh Dengue, also known as dengue fever, is a viral disease transmitted to ... New analysis highlights economic burden of dengue fever Dengue fever is a major public health concern in many parts of South- ... the first vaccine approved for the prevention of dengue disease caused by all dengue virus serotypes (1, 2, 3 and 4) in people ...
A sharp hike in the number of dengue fever cases has the citizens worried ... y son caught dengue fever twice," says Muhammad Shakoor, a resident of Lalazar. "The first time, I took him to the dengue ward ... Dengue season starts with monsoons and continues well into October in Rawalpindi. It had just begun this year when a sharp hike ... The dengue season starts with monsoons and lasts well into October in Rawalpindi. It had just begun this year when a sharp hike ...
Buy albums from the artist Dengue Fever on Midheaven Mailorder ... Dengue Fever. Sleepwalking Through The Mekong. Minky Records ... Dengue Fevers psychedelic take on the Cambodian pop sounds of the 60s makes them one of rock n rolls most unique success ... "Dengue Fever, or course, is quite possibly the most original pop band in LA." - Los Angeles Times ...
  • A dengue vaccine is approved for use in children aged 9 to 16 years with laboratory-confirmed previous dengue virus infection and living in areas where dengue is endemic (common). (cdc.gov)
  • Dengue typically occurs in tropi- dengue infection in the index patient. (cdc.gov)
  • Dengue is a public health concern because most of the population in tropical America is susceptible to infection. (medscape.com)
  • Go to Dengue and Severe Dengue Infection for complete information on these topics. (medscape.com)
  • Dengue and dengue hemorrhagic fever (DHF) result from infection by any of four serotypes of dengue viruses. (cdc.gov)
  • Dengue fever is a viral infection spread to people through bites from infected mosquitos . (medlineplus.gov)
  • If an infection is suspected, you will get a blood test to check for the dengue virus. (medlineplus.gov)
  • Although recovery from infection by one of the serotypes provides lifelong immunity against it, cross-immunity is only partial and subsequent infections by other serotypes increase the risk of developing severe dengue. (who.int)
  • Approximately 100 million people get sick from infection, and 40,000 die from severe dengue. (cdc.gov)
  • Clinical diagnosis of Dengue is conducted by laboratory testing on human serum and plasma tested for DENV SubT and dengue NS-1 (DENG NS-1), dengue IgG and IgM to confirm the presence of infection. (answers.com)
  • The World Health Organization recommends that the vaccine only be given to persons with confirmed prior dengue virus infection. (cdc.gov)
  • In May 2019, Dengvaxia® was approved by the U.S. Food and Drug Administration (FDA) in the United States for use in children 9-16 years old living in an area with endemic dengue with laboratory confirmed prior dengue virus infection. (cdc.gov)
  • Should 3-doses of Dengvaxia ® be administered routinely to persons 9-16 years of age with laboratory-confirmed previous dengue infection and living in endemic areas to prevent virologically confirmed dengue, hospitalizations and severe dengue? (cdc.gov)
  • Dengue fever, or breakbone fever, results from a viral infection carried by Aedes mosquitoes. (medicalnewstoday.com)
  • It can only be given to kids ages 9 to 16 who have had prior dengue infection. (npr.org)
  • A dengue vaccine called Dengvaxia has been approved for use in children and adolescents aged 9 to16 years who have had previous dengue virus infection and are living in an area where dengue is endemic. (medicinenet.com)
  • High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections. (broadinstitute.org)
  • Index cluster study of dengue virus infection in Nicaragua. (broadinstitute.org)
  • The global burden of dengue infection is more than triple current estimates from the World Health Organization, according to a multinational study published in the journal Nature . (ox.ac.uk)
  • Dengue, also known as 'breakbone fever', is a viral infection that is transmitted between humans by mosquitoes. (ox.ac.uk)
  • Until now, little was known about the current distribution of the risk of dengue virus infection and its public health burden around the world. (ox.ac.uk)
  • Jimmy Whitworth, Head of International Activities at the Wellcome Trust, said: 'Over time, this comprehensive map of global disease burden will also help to demonstrate which control measures are making the biggest difference in reducing the number of people suffering from dengue infection. (ox.ac.uk)
  • Dengue typically causes a mild first infection but a far worse one if someone is infected with the virus a second time. (eurekalert.org)
  • There are four types of dengue virus, and it is thought that the body's response to the first infection leads to more severe disease upon a second infection. (eurekalert.org)
  • In those who have previously been infected with dengue, the vaccine acts like a silent second infection, stimulating the immune system without the more severe symptoms that may accompany a natural second infection. (eurekalert.org)
  • In those who have not yet been infected with dengue, the vaccine causes the immune system to recognize that a first dengue infection has occurred and then when exposed to dengue in a natural setting, the body reacts as if it is getting a second infection that may be more severe. (eurekalert.org)
  • The manufacturers of the three-dose vaccine have acknowledged their vaccine does not work well in people who haven't previously had a naturally occurring dengue infection before vaccination, the researchers say. (eurekalert.org)
  • Ecological changes have favored the geographic expansion of the vector and, since the dengue pandemic in the Asian and Pacific regions, the infection became widely distributed worldwide, reaching Brazil in 1845. (hindawi.com)
  • Knowledge about the pathogenesis of dengue infection is limited, but both viral and immune host factors appear to be associated with severe illness [ 26 ]. (hindawi.com)
  • The U.S. Food and Drug Administration announced today the approval of Dengvaxia, the first vaccine approved for the prevention of dengue disease caused by all dengue virus serotypes (1, 2, 3 and 4) in people ages 9 through 16 who have laboratory-confirmed previous dengue infection and who live in endemic areas. (news-medical.net)
  • Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection. (news-medical.net)
  • Children with a history of prior dengue virus infection had a significantly lower risk of being symptomatic when infected by Zika virus, according to a new study in Nicaragua of more than 3,000 children aged 2 to 14 years. (sciencedaily.com)
  • Experts have worried that prior dengue virus infection could exacerbate severe Zika disease. (sciencedaily.com)
  • It has been observed that in some epidemiological settings, a second dengue infection can be much more severe than a first dengue infection. (sciencedaily.com)
  • Since dengue and Zika are closely related, it is important to know whether Zika following a dengue infection could also be more severe. (sciencedaily.com)
  • To examine this potential relationship, the authors studied the 2016 epidemic of Zika in a longstanding cohort of children in Managua, many of whom had dengue infection histories. (sciencedaily.com)
  • Using data from the 15 years of the pediatric cohort, the investigators determined exposure histories for 3,027 of the children, of which 743 children had at least one dengue infection. (sciencedaily.com)
  • In statistical models adjusted for sex and age (younger children are less likely to have had dengue virus infection), children with a previous dengue virus infection before March 2015 had a significantly lower risk of symptomatic Zika virus infection. (sciencedaily.com)
  • These data indicate that prior dengue immunity in children may be protective against symptomatic Zika infection, according to the authors. (sciencedaily.com)
  • Following infection with one serotype, subsequent infection with a different serotype increases a person's risk of severe dengue and death. (paho.org)
  • Advancements in genetic engineering have led to the development of genetically modified mosquitoes that are resistant to dengue virus infection. (thedailystar.net)
  • Studies have found that infection with one virus type increases the risk for severe dengue fever from a different dengue virus. (nih.gov)
  • The Epidemiological unit had already launched a week against dengue fever last October 7 to 13, before the arrival of monsoon rains, when the risk of infection is greater, especially in certain districts. (asianews.it)
  • Washington, April 12 (ANI): Scientists have identified the region on dengue virus that is neutralized in people who overcome infection with the deadly pathogen. (newstrackindia.com)
  • The leading theory to explain why some people develop dengue hemorrhagic fever is that under some conditions the human immune response can actually enhance the virus and disease during a second infection. (newstrackindia.com)
  • We have to figure out a way to develop dengue vaccines that induce the good response that protects against infection, at the same time avoiding the bad response that enhances disease," the researcher stated. (newstrackindia.com)
  • Nazmul said the dengue infection rate is highest in the Rohingya camps. (globalissues.org)
  • Despite having a high dengue infection rate in the camps, lack of awareness about the virus and the absence of prompt diagnosis of the disease make the Rohingya refugees more vulnerable. (globalissues.org)
  • Dengue virus infection is more and more acknowledged as one of the world's major escalating problems. (scirp.org)
  • Dengue (aka break-bone fever) is a viral infection that spreads from mosquitoes to people. (allafrica.com)
  • The development of animal models of dengue virus (DENV) infection and disease has been challenging, as epidemic DENV does not naturally infect non-human species. (mdpi.com)
  • The Tufts team set out to develop and test a Simoa-based dengue test hoping that the digital platform might be able to more sensitively detect anti-dengue antibodies, opening up the possibility of detecting the disease earlier after infection. (genomeweb.com)
  • Overall, the results suggest that Simoa may be able to detect dengue infection at a much earlier stage of infection as compared to ELISAs, the authors wrote. (genomeweb.com)
  • Global levels of dengue infection are more than three times higher than previous estimates from the World Health Organization, according to new research just published in the journal Nature . (planetsave.com)
  • Dengue, alternately known as 'breakbone fever', is a sometimes fatal viral infection that is transmitted to humans via mosquitoes. (planetsave.com)
  • Dengue vaccine Dengue is a mosquito-borne viral infection that causes fever, generalized body aches, and, if severe, external and internal bleeding (called dengue hemorrhagic fever). (msdmanuals.com)
  • She tested positive for both immunoglobulin G and immunoglobulin M dengue serology indicating she had secondary dengue infection, which placed her at risk for an exaggerated cytokine response as was evident clinically. (medscape.com)
  • Dengue is transmitted to humans through the bite of infected A aegypti mosquitoes. (medscape.com)
  • Click to expand Dengue is a mosquito-borne viral disease that is transmitted between humans by Aedes mosquitoes. (who.int)
  • Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. (wikipedia.org)
  • Dengue viruses (DENV) transmitted by Aedes aegypti mosquitoes present a growing public health challenge (Shepard et al. (cdc.gov)
  • A person is at risk of dengue fever if they live or travel in an area where dengue occurs and mosquitoes that can carry it live. (medicalnewstoday.com)
  • There are currently no licensed vaccines or specific treatments for dengue, and substantial efforts to control the mosquitoes that transmit the disease have not stopped its rapid emergence and global spread. (ox.ac.uk)
  • It is caused by any of four Dengue virus types or serotypes (DENV-1 to DENV-4) and is transmitted by mosquitoes from the genus Aedes . (hindawi.com)
  • Dengue, also known as dengue fever, is a viral disease transmitted to humans by mosquitoes of the genus Aedes. (news-medical.net)
  • Researchers have found a way to reduce the blood thirst of mosquitoes and prevent mosquito bites and spread of mosquito borne illnesses such as Zika, dengue fever, malaria and chikungunya. (news-medical.net)
  • Zika virus and dengue virus are both transmitted by Aedes aegypti mosquitoes and cause similar symptoms, including fever, rash, and joint pain. (sciencedaily.com)
  • The first step to prevent dengue is within our homes, it is important to remove any space or container than can hold unnecessary stagnant water which may become breeding sites of mosquitoes," Health Secretary Francisco Duque III said. (inquirer.net)
  • So a lot of mosquitoes that can transmit dengue will be moving towards regions that are now considered to be temperate, either north or south of the tropics. (cosmosmagazine.com)
  • Dengue fever occurs in tropical and subtropical areas of the world, where it is spread by mosquitoes. (nih.gov)
  • According to health experts, active monitoring and surveillance of mosquitoes is necessary to keep a check on spread of the dengue virus. (com.pk)
  • Villagers surveyed had high knowledge of dengue transmission, of the Aedes mosquitoes that transmit dengue and of how to prevent breeding and biting. (phnompenhpost.com)
  • Dengue fever is an arbovirus transmitted by Aedes mosquitoes (both Ae. (who.int)
  • An economic evaluation from the societal perspective is salient, comparing the regular control program for dengue prevention versus an intervention of environmental management strategy by covering the most Aedes aegypti productive breeding sites with insecticide covers and additional activities. (medscape.com)
  • 10) Adding to the concern of indigenous dengue transmission is the recent establishment in the United States of another known dengue vector, Aedes albopictus, which was probably imported in shipments of tires from Asia. (cdc.gov)
  • Dengue fever is an infectious disease caused by dengue virus that comes from the bite of Aedes aegypti mosquito. (answers.com)
  • Dengue is a flu-like viral disease that is spread by the bite of an infected mosquito (Aedes mosquito). (answers.com)
  • In the Americas, Aedes aegypti is the mosquito vector that is the main source of dengue transmission. (paho.org)
  • Nazmul said Rohingya refugees live in a limited space in the camps where there is not enough scope to runoff rainwater, so stagnant water creates an enabling environment for the breeding Aedes mosquito, carrier of the dengue virus. (globalissues.org)
  • A person contracts dengue when an infected female Aedes aegypti mosquito bites him or her. (ibtimes.com)
  • Vertical transmission in Aedes aegypti and Aedes albopictus is considered a maintenance mechanism for dengue virus (DENV) during unfavorable conditions and may be implicated in dengue outbreaks. (nature.com)
  • On November 7, 2022, dengue virus (DENV), which is not endemic in the continental United States, [ 1 ] was identified in a Maricopa County, Arizona resident by reverse transcription-polymerase chain reaction (RT-PCR) testing at Arizona State Public Health Laboratory (ASPHL). (medscape.com)
  • Dengue, frequently called breakbone fever, is endemic to large areas of the tropics and subtropics, including the Caribbean Islands. (medscape.com)
  • The second reason dengue should concern health care providers in this country is the potential for encountering cases of dengue among travelers arriving from dengue-endemic areas. (cdc.gov)
  • all the rest were travelers arriving from dengue-endemic areas. (cdc.gov)
  • A vaccine with varying level of effectiveness for each of the 4 dengue viruses is available (and others are being researched), and WHO has issued a conditional recommendation on the use of the vaccine for highly endemic areas. (who.int)
  • Therefore, travelers returning from endemic areas are unlikely to have dengue fever if symptoms start more than 14 days after arriving home. (wikipedia.org)
  • There are 4 dengue virus serotypes (DENV-1, DENV-2, DENV-3 and DENV-4), all of which circulate globally, with most endemic coun-tries reporting circulation of all 4 serotypes in recent years. (cdc.gov)
  • Wear a long-sleeved shirt and long trousers while visiting a dengue-endemic region. (medicinenet.com)
  • Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission. (broadinstitute.org)
  • With endemic transmission in Asia and the Americas, recent outbreaks in Portugal, the ever-increasing incidence in Africa, and the challenges of making an effective dengue vaccine or controlling the vector, Professor Farrar stresses: 'This really does represent a crucial period in the global spread of dengue. (ox.ac.uk)
  • Dengue is an endemic problem in several countries including India. (medindia.net)
  • UNC investigators identified 7 local individuals who had contracted dengue during travel to an endemic region and sent blood cells from these individuals to Vanderbilt School of Medicine. (newstrackindia.com)
  • Dengue is an endemic disease of tropical areas that causes high fevers, headaches, nausea, vomiting, muscle pain, and in the most severe cases, hemorrhages that can be fatal. (ticotimes.net)
  • Health brigades spray one of South America's largest cemeteries in Lima to eradicate the dengue-transmitting mosquito and collect larvae in an attempt to control a new outbreak of the endemic disease in Peru, which has killed about 30 people this year. (euronews.com)
  • RT-PCR tests are available for early dengue diagnosis, but serological methods are more cost effective and easily available making them attractive, especially in dengue endemic countries. (genomeweb.com)
  • Dengue-endemic areas include the United States territories of American Samoa, Puerto Rico, and the U.S. Virgin Islands, and freely associated states, including the Federated States of Micronesia, the Republic of Marshall Islands, and the Republic of Palau. (msdmanuals.com)
  • The incidence of dengue hemorrhagic fever is increasing among the adult population living in endemic areas. (medscape.com)
  • Dengue is an acute systemic viral infectious disease, established worldwide in epidemic and endemic transmission cycles. (bvsalud.org)
  • However, the latest data of the DGHS revealed that 1,283 people were infected with and 26 people died of dengue in the Rohingya camps and surrounding host community in Ukhiya and Teknaf upazilas of Cox's Bazar from January 1 to June 6, 2023. (globalissues.org)
  • An alternative name for dengue, "breakbone fever", comes from the associated muscle and joint pains. (wikipedia.org)
  • During the eighteenth century, dengue (present-day chikungunya) was distinguished from breakbone fever (present-day dengue), another febrile exanthem. (languagehat.com)
  • Dengue-like epidemics occurred in Egypt and on Java in 1779, but these may actually have been caused by chikungunya virus. (cdc.gov)
  • These viruses, chikungunya and zika , are common in the same places as the dengue virus, and they cause similar symptoms. (medlineplus.gov)
  • New research presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Amsterdam, Netherlands shows that the geographical range of vector-borne diseases such as chikungunya, dengue fever, leishmaniasis, and tick-borne encephalitis is expanding rapidly. (news-medical.net)
  • In April, the WHO issued a warning that climate change could trigger a worldwide surge in mosquito-borne diseases, including dengue, Zika, and Chikungunya. (medindia.net)
  • Chikungunya and Dengue. (languagehat.com)
  • In 1952, chikungunya virus was recovered during an outbreak in Tanzania, but by then, the virus had lost its original name to present-day dengue viruses. (languagehat.com)
  • There are sections on "The Chikungunya Epidemic of 1827-1828," "Origin of the Term Dengue," "Discovery of Chikungunya Pandemics," "History of Disease Caused by Dengue Viruses," and "History of Chikungunya Name Change. (languagehat.com)
  • Como diferenciar Dengue, Chikungunya e Zika? (bvs.br)
  • Dengue outbreaks are occurring in many countries of the world. (cdc.gov)
  • Outbreaks of dengue in nearby Caribbean, Central American, and South American countries increase the likelihood of future autochthonous transmission among people in Florida and Southeastern states. (medscape.com)
  • 1) Outbreaks of the more severe form of dengue, DHF, occurred in Cuba in 1981 (2) and in Venezuela in 1989. (cdc.gov)
  • 9) Outbreaks of indigenous dengue transmission occurred in Texas in 1980 and again in 1986. (cdc.gov)
  • Outbreaks of dengue fever are rare in the U.S. mainland. (medlineplus.gov)
  • Reports of dengue and severe dengue epidemics in the Region started in 1998 and have increased in frequency and spread ever since, with outbreaks occurring in Djibouti, Egypt, Oman, Pakistan, Saudi Arabia, Somalia, Sudan, and Yemen. (who.int)
  • All the 4 serotypes of dengue virus have been known to have circulated in the Region during these outbreaks. (who.int)
  • A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals a novel NS5 mutation. (broadinstitute.org)
  • This review addresses vector distribution, dengue outbreaks, circulating serotypes and genotypes, and prevention approaches being utilized in Brazil. (hindawi.com)
  • MANILA, Philippines-Amid the measles outbreaks in different regions in the country, the Department of Health (DOH) on Friday reported that number of dengue cases nationwide have spiked to 36,664. (inquirer.net)
  • During the monsoon, Bangladesh experiences spikes in dengue outbreaks. (globalissues.org)
  • Unusual rainfall occurred in Cox's Bazar area earlier this year, triggering dengue outbreaks in the camps. (globalissues.org)
  • Kabir said the dengue national guideline should be revisited to check dengue outbreaks across the country, including Rohingya camps. (globalissues.org)
  • Over 300 people were killed and more than 136,000 infected by the dengue epidemic last year in one of the country's worst-ever outbreaks of the disease in recent times. (xinhuanet.com)
  • While most people focus on the prevention of Covid-19, the risk of catching dengue fever tends to be overlooked, he said. (bangkokpost.com)
  • An outbreak of dengue fever on a small island chain in the middle of the Pacific. (cdc.gov)
  • Health officials in Guwahati, Assam, are reporting a new outbreak of dengue fever, which has so far claimed three lives over the last eight days while many more have been hospitalized. (medindia.net)
  • The test is used if you have symptoms of dengue fever and have been in an area where mosquitos carry the virus. (medlineplus.gov)
  • You may need to be tested for the dengue virus if you have symptoms of dengue fever and have been in an area where the virus is common. (medlineplus.gov)
  • Symptoms of dengue fever will depend on the severity of the disease. (medicalnewstoday.com)
  • The signs and symptoms of dengue fever are similar to some other diseases such as influenza and malaria . (medicalnewstoday.com)
  • Although the incidence of hemorrhagic dengue in United States travelers abroad is low,(13,15) clinicians in this country may encounter severe cases of dengue, particularly among immigrants from areas with a high incidence of DHF. (cdc.gov)
  • Every year the incidence of dengue, along with that of other diseases such as diarrhoea and heat stroke, rises sharply as summer approaches," said Dr Opas Karnkawinpong, director-general of the DDC, on Sunday. (bangkokpost.com)
  • The only approved vaccine for dengue may actually increase the incidence of dengue infections requiring hospitalization rather than preventing the disease if health officials aren't careful about where they vaccinate, new public health research published Sept. 2 in Science suggests. (eurekalert.org)
  • The incidence of dengue in Brazil has been frequently high, and the number of cases in the country has at some point in time represented up to 60% of the dengue reported cases worldwide. (hindawi.com)
  • Dengue incidence has increased in the Americas over the past four decades, from 1.5 million cumulative cases in the 1980s to 16,2 million in the decade 2010-2019. (paho.org)
  • The global incidence of dengue has grown dramatically in recent decades, putting about half of the world's population at risk. (newstrackindia.com)
  • The province was selected based on its high dengue incidence rate, according to the study. (phnompenhpost.com)
  • These findings highlight the need to give closer consideration to future urban planning and development, taking into consideration the changing demography and the importance of built environment to mitigate the increasing incidence of dengue in the non- urban areas of Malaysia . (bvsalud.org)
  • Researchers at QUT and QIMR Berghofer Medical Research Institute have found that the dengue fever mosquito common to north and central Queensland poses the greatest danger of spreading the Zika virus in Australia. (news-medical.net)
  • However, the new findings indicate that prior dengue immunity in children may in fact be protective against symptomatic Zika disease. (sciencedaily.com)
  • While dengue virus has been entrenched in the Americas for decades, Zika virus was not reported in the region until 2015. (sciencedaily.com)
  • However, many people do not show symptoms when infected with either Zika virus or dengue virus. (sciencedaily.com)
  • However, prior dengue virus infections did not affect the rate of total Zika virus infections, which includes both symptomatic and clinically inapparent cases. (sciencedaily.com)
  • They note that future research should investigate the immunological mechanisms of cross-protection between dengue virus and Zika virus and examine whether dengue immunity is protective against congenital Zika syndrome or Zika-related neurological complications. (sciencedaily.com)
  • Dengue hemmorhagic fever (DHF) is a more severe form of dengue fever associated with thrombocytopenia and hemoconcentration. (medscape.com)
  • dengue virus serotype 1 was isolated from 15 patients. (cdc.gov)
  • 6 days symptoms (6): myalgia, headache, arthralgia, eye or after illness onset and were negative for virus isolation and retroorbital pain, rash, or hemorrhagic manifestation (e.g., for anti-dengue IgM. (cdc.gov)
  • Dengue fever is a mosquito-borne viral disease caused by 1 of 4 antigenically distinct dengue flaviviruses: dengue virus 1 (DEN-1), dengue virus 2 (DEN-2), dengue virus 3 (DEN-3), and dengue virus 4 (DEN-4). (medscape.com)
  • You can't catch the virus from a person who is sick with dengue fever. (medlineplus.gov)
  • A dengue fever test checks a sample of your blood to see if you have the virus. (medlineplus.gov)
  • Most people who get the dengue virus won't become sick. (medlineplus.gov)
  • That's why it's so important to get a dengue fever test if you have symptoms after being in an area where the virus is common. (medlineplus.gov)
  • Molecular tests look for genetic material from the dengue virus in your blood sample. (medlineplus.gov)
  • A dengue fever test is used to find out if you have the dengue virus. (medlineplus.gov)
  • Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. (wikipedia.org)
  • Typically, people infected with dengue virus are asymptomatic (80%) or have only mild symptoms such as an uncomplicated fever. (wikipedia.org)
  • Dengue is caused by one of any of four related viruses: Dengue virus 1, 2, 3, and 4. (cdc.gov)
  • For this reason, a person can be infected with a dengue virus as many as four times in his or her lifetime. (cdc.gov)
  • The name of the microorganism is the dengue virus. (answers.com)
  • After being bitten by a mosquito carrying the virus, the incubation period ranges from three to 15 (usually five to eight) days before the signs and symptoms of dengue appear. (answers.com)
  • Age, co-morbidities, host genetics, and virus strain are risk factors for severe dengue with heterotypic secondary infections being the most prominent factor associated with severe dengue (Wilder-Smith et al. (cdc.gov)
  • Four strains of the dengue virus may cause DF. (medicinenet.com)
  • However, the antibodies attacking one strain don't attack other strains of the dengue virus. (medicinenet.com)
  • If your body gets infected by a different version of the dengue virus, it may trick the antibody to attack it. (medicinenet.com)
  • Genetic diversity and lineage dynamic of dengue virus serotype 1 (DENV-1) in Cambodia. (broadinstitute.org)
  • Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia. (broadinstitute.org)
  • The research has created the first detailed and up-to-date map of dengue distribution worldwide, enabling researchers to estimate the total numbers of people affected by the virus globally, regionally and nationally. (ox.ac.uk)
  • They found that while the vaccine can reduce illness and hospitalization by 20 to 30 percent in places where there is high transmission of dengue, it may actually significantly increase illness and hospitalization if used in locations where there is lower transmission of the virus. (eurekalert.org)
  • Dengue is an arthropod-borne disease caused by the Dengue virus (DENV) [ 1 ]. (hindawi.com)
  • Dr Paulo Rocha from the University of Bath's Department of Electronic & Electrical Engineering is developing a low-cost integrative sensing tool for early detection of Dengue virus, using a novel platform containing electrical sensors to investigate the behavior of human cells infected with Dengue virus. (news-medical.net)
  • We've commissioned ads in print and on television to caution the citizens against the dengue virus and counter its spread by keeping their homes mosquito-free," he adds. (com.pk)
  • According to media reports, between 300 and 400 people were being tested for dengue virus at government-run healthcare facilities daily. (com.pk)
  • It is transmitted by the bite of a mosquito infected with one of the four serotypes of dengue virus. (paho.org)
  • Injections of nanoparticles immunised mice against the dengue virus for nearly seven months, a US study has shown. (cosmosmagazine.com)
  • The mosquito-borne dengue virus currently afflicts more than 350 million people in more than 120 different countries each year. (cosmosmagazine.com)
  • And immunising against more than one serotype, using bits of actual dengue virus, can dial down any protection bestowed by previous immunisations. (cosmosmagazine.com)
  • They built and tested a new type of vaccine to combat serotype 2 of the dengue virus using nanoparticles studded with copies of DENV2-E, a key protein from that particular serotype. (cosmosmagazine.com)
  • But he advises people to view the report with a little scepticism as there are still important questions that remain to be answered about the process before it can be endorsed as a solution to the dengue virus. (cosmosmagazine.com)
  • Round dengue virus particles revealed in a tissue specimen. (nih.gov)
  • Just one dose of a low-cost vaccine proved safe and stimulated a strong immune response against the dengue virus in most participants in an early-stage clinical trial. (nih.gov)
  • In previous work, a research team led by Dr. Anna Durbin of Johns Hopkins University tested vaccine candidates against each dengue virus. (nih.gov)
  • The finding achieved by a team of scientists from the University of North Carolina at Chapel Hill and Vanderbilt University challenge the current state of dengue vaccine research, which is based on studies in mice and targets a different region of the virus. (newstrackindia.com)
  • In the past researchers have relied on mouse studies to understand how the immune system kills dengue virus and assumed that the mouse studies would apply to people as well," said senior study author Aravinda M. de Silva, PhD, associate professor of microbiology and immunology at the UNC School of Medicine. (newstrackindia.com)
  • The new research was performed using blood cells from local travelers infected with dengue virus. (newstrackindia.com)
  • Creation of a vaccine is complicated by the fact that there are four distinct, but closely related forms of the virus that cause dengue. (newstrackindia.com)
  • But if they become infected with one of the other three forms of the virus, they increase their chances of developing the severe bleeding and sometimes fatal dengue hemorrhagic fever and dengue shock syndrome. (newstrackindia.com)
  • The team found that instead of binding to small fragments of the virus-like mouse antibodies do-human antibodies that neutralized the virus bound to a complex structure that was only present on a completely assembled dengue virus. (newstrackindia.com)
  • Though this is the first time this phenomenon has been shown with dengue, just last year there were a number of studies showing that antibodies recognize similar complex epitopes in both HIV and West Nile Virus," said de Alwis. (newstrackindia.com)
  • Their group's indirect Simoa method relies on inactivated dengue virus type 2 antigen-coated magnetic beads for the capture of dengue-specific antibodies, the authors wrote. (genomeweb.com)
  • The dengue fever revisited Punjab as 47 new cases of the virus were reported in the province in the last two days, reported Express 24/7 . (com.pk)
  • To diagnose dengue, doctors do blood tests to check for the virus or antibodies to the virus. (msdmanuals.com)
  • The dengue virus is thus spread to other people (called local transmission). (msdmanuals.com)
  • Although uncommon, a pregnant woman can pass the dengue virus to her fetus during pregnancy or around the time of birth (see World Health Organization [WHO]: Dengue and severe dengue ). (msdmanuals.com)
  • There has been one report of dengue virus passing through breast milk. (msdmanuals.com)
  • There are four types of dengue virus (serotypes). (msdmanuals.com)
  • Autochthonous dengue infections were last reported in Hawaii (4). (cdc.gov)
  • After the Second World War, no confirmed autochtho- cases of dengue hemorrhagic fever or shock syndrome nous dengue infections were reported in Hawaii. (cdc.gov)
  • 50-100 million dengue Methods infections and several hundred thousand cases of DHF occur annually (2). (cdc.gov)
  • It is mostly used for people who have symptoms related to dengue fever and have recently traveled to an area where dengue infections are common. (medlineplus.gov)
  • The team estimate that there are 390 million dengue infections across the globe each year, of which 96 million reach any level of clinical or subclinical severity. (ox.ac.uk)
  • Symptomatic infections vary from a mild, flu-like illness known as dengue fever (DF) to a life-threatening form called severe dengue (SD) [ 8 ]. (hindawi.com)
  • He said the risk of dengue infections climbs in densely populated areas. (globalissues.org)
  • He observed that dengue spreads very fast, but the authorities have not controlled dengue infections in the highly-crowded refugee camps in Cox's Bazar. (globalissues.org)
  • In 2022, 17 refugees died from dengue infections in Rohingya camps. (globalissues.org)
  • El Gedaref in eastern Sudan is witnessing an increase in dengue fever* infections, with 70 confirmed cases and two deaths reported last week alone. (allafrica.com)
  • Florida health department officials confirmed the 11th case of dengue fever on Tuesday, July 7, in the state that was already beleaguered by an increasing number of coronavirus infections. (ibtimes.com)
  • With additional clinical validation, the method could provide a means to distinguish between primary and secondary infections and identify those at risk for developing dengue hemorrhagic fever or shock syndrome. (genomeweb.com)
  • Dengue is considered the most serious re-emergent viral disease transmitted by arthropods, with approximately 390 million infections worldwide each year, 7% of which occur in Brazil 1 , 2 . (nature.com)
  • The Department of Disease Control (DDC) is warning that this year's seasonal outbreak of dengue may be more severe than usual, following three early deaths in 2022 -- already half the tally for the whole of 2021. (bangkokpost.com)
  • Official data showed that dengue cases increased significantly in 2022 when the monsoon started. (globalissues.org)
  • From 1981 through 1986, 796 386 cases of DHF and 9774 deaths caused by dengue were reported to the World Health Organization (WHO) from countries in Southeast Asia. (cdc.gov)
  • 7) Deaths occurred during dengue epidemics in Australia in 1897 and in Greece in 1928, when over 1000 deaths were reported. (cdc.gov)
  • The harms considered critical outcomes were serious adverse events, hospitalizations, severe dengue and deaths. (cdc.gov)
  • Last year only six people died because of dengue while this year three dengue deaths have been reported in just the first three months," he said. (bangkokpost.com)
  • Even though most patients who catch dengue are children and adolescents, most dengue-related deaths are among the elderly, people living with a chronic disease and the obese, he said. (bangkokpost.com)
  • Prof. Biswas said the team would also try to understand why there were dengue deaths after patients were admitted to hospitals. (thehindu.com)
  • According to data from the Ministry of Health, between January and August there have been 22 deaths from dengue in the country. (ticotimes.net)
  • About 50 to 100 million cases of dengue and about 20,000 deaths occur worldwide. (msdmanuals.com)
  • Two types of dengue vaccine have been approved and are commercially available. (wikipedia.org)
  • Professor Farrar states: "This really does represent a crucial period in the global spread of dengue. (planetsave.com)
  • The vaccine is not approved for use in U.S. travelers who are visiting but not living in an area where dengue is common. (cdc.gov)
  • Science, not bureaucracy, must be the driving force behind our fight against dengue. (thedailystar.net)
  • On investiga- engue viruses cause a wide range of illness, including tion by HDOH staff, dengue fever was suspected, and clin- dengue fever (DF), dengue hemorrhagic fever (DHF), ical specimens were collected and forwarded to the and dengue shock syndrome (DSS). (cdc.gov)
  • Severe dengue can cause internal bleeding and shock , which can be life-threatening. (medlineplus.gov)
  • In a small proportion of cases, the disease develops into a more severe dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. (wikipedia.org)
  • Severe dengue can involve shock and hemorrhagic fever. (medicalnewstoday.com)
  • Severe symptoms can indicate dengue shock syndrome (DSS) and dengue hemorrhagic fever (DHF). (medicalnewstoday.com)
  • Dengue hemorrhagic fever occurs when blood leaks from blood vessels into other parts of the body, which can lead to failure of the circulatory system, shock and possibly death, without prompt treatment. (eurekalert.org)
  • Severe dengue was previously known as dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS) [ 8 ]. (hindawi.com)
  • The illness can evolve to severe dengue, characterized by shock, respiratory distress, severe bleeding, and/or serious organ impairment. (paho.org)
  • The disease can evolve into severe dengue, characterized by shock, shortness of breath, severe bleeding and / or complications in the organs. (paho.org)
  • However, a clinician must be particularly watchful in treating a pregnant dengue-infected patient as physiologic hematology changes provide greater volume compensation and the advent of shock marks significant volume loss. (medscape.com)
  • Four different viruses can cause dengue fever. (medicalnewstoday.com)
  • Four related viruses can cause dengue fever: DENV-1, DENV-2, DENV-3, and DENV-4. (nih.gov)
  • Presenters will also review dengue clinical classification, diagnosis, and general treatment guidelines based on World Health Organization and Centers for Disease Control and Prevention recommendations. (cdc.gov)
  • Dengue prevention and control must be intersectoral and involve the family and the community. (paho.org)
  • PAHO/WHO provides advice and technical support for dengue prevention and control based on a regional strategy adopted by PAHO / WHO member States in 2016, called the " Strategy for arboviral disease prevention and control " (CD55.R6). (paho.org)
  • WHO (1997) Dengue Hemorrhagic Fever: Diagnosis, Treatment, Prevention and Control. (scirp.org)
  • A new study has found that despite knowledge of dengue prevention being widespread, preventative action is rarely taken. (phnompenhpost.com)
  • Whole genome sequencing by CDC's Dengue Branch later revealed that closely related DENV-3 strains not known to be circulating in the patient's travel region were identified in both patient A and pool A, suggesting local DENV transmission. (medscape.com)
  • Nevertheless, the involved DENV type and the host genetic makeup may explain some differences in clinical manifestations observed, since genetic polymorphisms appear to provide protection or predispose to more severe forms of dengue [ 27 ]. (hindawi.com)
  • The four dengue serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) circulate throughout the Americas, and in some countries simultaneously. (paho.org)
  • In contrast, certain immunodeficient mouse models infected with mouse-adapted DENV strains show signs of severe disease similar to the 'vascular-leak' syndrome seen in severe dengue in humans. (mdpi.com)
  • LAHORE:The anti-dengue drive initiated by the district administration is in full swing under which surveillance is being carried out at various points in the provincial capital. (com.pk)
  • In this regard, Lahore Deputy Commissioner Rafia Haider visited Union Council (UC) 120 Johar Town on Monday and inspected anti-dengue arrangements and instructed house owners about dengue preventive measures. (com.pk)
  • She also checked attendance and performance of the anti-dengue squad. (com.pk)
  • In the study, published this week online as an accepted manuscript in the Journal of Clinical Microbiology , the Tufts group described their development of a Simoa-based assay to detect type 2 anti-dengue IgG and IgM and compared its sensitivity to two commercially available ELISA kits for the two antibodies. (genomeweb.com)
  • According to the group, currently used ELISAs for anti-dengue antibody detection suffer from a lack of sensitivity in the first few days of illness, when antibodies against the disease may be present at too low a concentration to be detected. (genomeweb.com)
  • In contrast, the IgG Simoa was able to detect anti-dengue IgG at 1:10,000,000 dilution, making it 1,000 times more sensitive than the EuroImmun IgG ELISA kit. (genomeweb.com)
  • Similarly, the IgM Simoa was able to detect anti-dengue IgM at 10,000 times higher dilution than the EuroImmun IgM ELISA kit. (genomeweb.com)
  • Persons with dengue flaviviruses in their blood can transmit the flaviviruses to the mosquito (the vector) 1 day before the onset of the febrile period. (medscape.com)
  • The life span of A aegypti , the primary vector of dengue in the Americas, is usually 21 days. (medscape.com)
  • Dengue Branch and the Division of Vector Borne Infectious Diseases, Centers for Disease Control, CID, Fort Collins, CO. Duane J. Gubler, Sc.D and Edward B. Hayes, MD. (cdc.gov)
  • The mosquito becomes a vector after it has bitten an dengue infected carrier - usually another Human. (answers.com)
  • the main vector of dengue, has proved highly difficult to control, and continues to expand its geographic range. (cdc.gov)
  • is the vector mosquito for dengue and is widely distributed in the Americas. (paho.org)
  • Only Canada and continental Chile are free from dengue and its vector. (paho.org)
  • One of the earliest, if not the first, dengue epidemics described in the medical literature occurred in Philadelphia in 1780. (cdc.gov)
  • 5-7) Dengue epidemics were reported in various parts of the south- eastern United States through the 19th and 20th centuries, (6) most recently in Louisiana in 1945. (cdc.gov)
  • 7) Dengue or dengue-like epidemics were reported through- out the 19th and early 20th centuries in the Americas, southern Europe, North Africa, the Middle East, Asia and Australia and on various islands in the Indian Ocean, South and Central Pacific and the Caribbean. (cdc.gov)
  • 17) Hemorrhagic manifestations, including gastrointestinal hemorrhage, were described during dengue epidemics in Texas and Louisiana in 1922. (cdc.gov)
  • However, even though São Paulo is the most populous city in the Americas and has experienced major dengue epidemics, natural vertical transmission had never been detected in this area before. (nature.com)
  • Despite the fact that São Paulo, the capital of the state, is the most populous city in Brazil and Latin America 22 and in recent years has experienced major dengue epidemics, such as those in 2014 and 2015 23 , natural vertical transmission has never been detected in the city 15 . (nature.com)
  • Researchers have now conducted an analysis of the economic burden of dengue fever in Burkina Faso, Kenya and Cambodia. (news-medical.net)
  • With further development, the vaccine may help ease the burden of dengue fever in developing countries. (nih.gov)
  • A vaccine to prevent dengue (CYD-TDV, Dengvaxia®) is licensed and available in 20 countries for people ages 9-45 years old. (cdc.gov)
  • It's a vaccine to prevent dengue. (npr.org)
  • An animal reservoir is not necessary to maintain the cycle of transmission of dengue fever, but an animal reservoir in the form of monkeys appears to exist in limited areas of Africa. (medscape.com)
  • mosquito, one of the primary vectors for the transmission of dengue fever around the world. (who.int)
  • The US Advisory Committee on Immunization Practices (ACIP) Dengue Vaccine Work Group reviewed Dengvaxia ® safety and efficacy data in a systematic literature review in 2018. (cdc.gov)
  • MARA CEPEDA: Suspends the sale of the controversial Dengvaxia dengue vaccine for a year. (npr.org)
  • Using the only licensed dengue vaccine, Dengvaxia, the Philippines launched its first public immunisation program for dengue fever for more than a million children in April. (cosmosmagazine.com)
  • The majority of those were excluded as describing different live attenuated dengue vaccines or not including primary trial data. (cdc.gov)
  • In vaccines you hope for more than 30 percent success, but it's the only vaccine available right now to slow dengue," says Isabel Rodriguez-Barraquer, MD, PhD, MHS, a research associate at the Bloomberg School and one of the study's lead authors. (eurekalert.org)
  • The authors hope that their analysis can help inform policymakers in evaluating this and other candidate dengue vaccines. (eurekalert.org)
  • Overall, each model has its advantages and disadvantages and is differentially suited for studies of dengue pathogenesis and immunopathogenesis and/or pre-clinical testing of antiviral drugs and vaccines. (mdpi.com)
  • [ 2 ] Cases of dengue fever reported in Texas and Israel occurred from travelers who were infected with dengue while visiting other countries. (medscape.com)
  • Hundreds of thousands of cases of dengue and DHF are reported each year in tropical regions of the Americas, Africa, Asia and Oceania. (cdc.gov)
  • From 1980 through 1987, 879 632 cases of dengue were reported to the Pan American Health Organization from countries in the American region. (cdc.gov)
  • 13-15) From 1980 through 1989, 1457 suspected and 276 confirmed cases of dengue in the continental United States and Hawaii were reported to the Centers for Disease Control. (cdc.gov)
  • Between 0.5% and 5% of cases of dengue fever become severe. (medicalnewstoday.com)
  • The DC instructed the field teams to ensue registration of dengue cases response on official dashboard and also ensure door marking after indoor surveillance. (com.pk)
  • Citing data from the DOH Epidemiology Bureau, the Health department said dengue cases in the first two months of the year was 14,703 cases higher compared to the 21,961 dengue cases recorded during the same period in 2018. (inquirer.net)
  • Officials say that a total of 71 cases of dengue have been reported from across the capital this week alone. (medindia.net)
  • Over the last 24 hours, there has been a notable increase in dengue patients, surpassing the total number of cases in Bihar, which now exceeds 13,000. (medindia.net)
  • Dengue fever outbreak in Lucknow: The cumulative count of dengue cases in Lucknow has now reached 1,308. (medindia.net)
  • Dengue Cases in Kolkata: The number surpasses the 1,102 cases reported in the preceding week. (medindia.net)
  • The dengue situation in Bengal has reached a critical stage, with the number of cases exceeding the 50,000 mark. (medindia.net)
  • The government of Guatemala declared a national emergency on Thursday due to a dengue outbreak that has left 22 dead and more than 12,000 cases so far this year, Health Minister Francisco Coma reported. (ticotimes.net)
  • The highest historical peak of dengue in Guatemala was registered in 2019 when there were more than 50,000 cases, according to official statistics. (ticotimes.net)
  • With the monsoon refugees in the cramped camps in Cox's Bazar are expected to be impacted by an increase of dengue, which last year accounted for 1,283 cases in the Rohingya camps. (globalissues.org)
  • A total of 1,066 dengue cases were reported in highly cramped refugee camps in Cox's Bazar up to May 23 this year, while the case tally was only 426 among the local community there," Dr Nazmul Islam, Director of Disease Control and Line of the Directorate General of Health Services (DGHS), said. (globalissues.org)
  • Similarly, the Emergency Health Department in Um Ruwaba locality in North Kordofan detained two cases of dengue fever in the isolation ward for infectious diseases after local tests confirmed that the cases were positive. (allafrica.com)
  • The Director General of the Ministry of Health in North Kordofan, El Fatih Nour, denied the presence of other cases of dengue fever aside from the two in Um Ruwaba. (allafrica.com)
  • The federal capital has reported 96 more dengue cases in the last 24 hours taking the total tally of cases to 2,331 in the current season. (com.pk)
  • Overall 1,379 dengue cases have been reported in rural and 952 have emerged from urban areas of Islamabad. (com.pk)
  • The total number of dengue cases has gone up to 2,331 cases while six people have lost their lives to the viral disease in the current year. (com.pk)
  • On Thursday, the federal capital reported 73 more dengue cases taking the total tally of cases to 2,235 in the current season. (com.pk)
  • While Punjab has reported at least 6,378 dengue cases in the current season, the secretary of health told. (com.pk)
  • A total of 4,816 cases have been reported, including 21 cases of the potentially fatal hemorrhagic dengue. (foxnews.com)
  • Dengue cases usually flare up from August to January. (foxnews.com)
  • Dengue claimed a record 31 lives during a 2010 epidemic that saw more than 12,000 suspected cases. (foxnews.com)
  • The dengue cases are located in Key Largo, around 60 miles south of Miami. (ibtimes.com)
  • Reports said all dengue cases, which include eight discovered in late June, are in Key Largo, around 60 miles south of Miami. (ibtimes.com)
  • In the last 24 hours, 39 cases of dengue were reported in Lahore, two in Faisalabad and four in Sargodha. (com.pk)
  • Owing to the rising number of dengue cases in the city, all teaching hospitals in Lahore have established special counters for dengue patients in their emergency departments on the instructions of the Health Department. (com.pk)
  • Meanwhile, dengue cases are currently on the rise this year due to a naturally occurring uptick in breeding. (phnompenhpost.com)
  • During the first six weeks of this year, there were some 600 dengue cases reported - double the number of cases during the same period in 2017, Leang said. (phnompenhpost.com)
  • A few cases of locally transmitted dengue have occurred in Hawaii, Florida, and Texas. (msdmanuals.com)
  • Break Dengue is an open platform that crowdsources information "on the ground" with a view to accurately predictdengue fever cases around the globe. (who.int)
  • Total population, gross domestic product (GDP) per capita, USW, number of dengue cases and rainfall index were investigated. (bvsalud.org)
  • The larger the total population, purchasing power or socioeconomic status (GDP per capita) and the generation of MSW, the greater the number of dengue cases. (bvsalud.org)
  • Classical dengue with rash after appropriate incubation in first and subsequent volunteers and Ae aegypti transmission. (cdc.gov)
  • For most people, the best way to prevent dengue fever is to take steps to avoid mosquito bites. (medicalnewstoday.com)
  • A serosurvey conducted after the first confirmed dengue outbreak in Peru in 1990 demonstrated that an earlier outbreak of dengue transmission had been undetected. (medscape.com)
  • Dengue is prevalent in most tropical and subtropical countries. (scirp.org)
  • Although they [nanoparticles] have been used before, this case is important because the nanoparticles have shown that they can achieve a significant antibody response to dengue for a longer time period," says Prasad Paradkar, a research team leader at the Australian science organisation CSIRO who focuses on mosquito-borne viruses but was not involved with the study. (cosmosmagazine.com)
  • Epidemic dengue occurred again on Oahu in Hawaii in 1944. (cdc.gov)
  • Gubler, D.J. and Trent, D.W. (1994) Emergence of Epidemic Dengue/Dengue Hemorrhagic Fever as a Public Health Problem in the Americas. (scirp.org)
  • SAN JUAN, Puerto Rico - Puerto Rico's health department has declared a dengue epidemic. (foxnews.com)
  • The residents of Lahore are the most affected by the outbreak , and healthcare experts have warned of a dengue epidemic in the province if urgent and solid preventive steps are not taken by the concerned authorities. (com.pk)
  • Dengue is currently the most widely spread mosquito-borne disease in WHO's Eastern Mediterranean Region. (who.int)
  • As dengue figures surge, the DOH asked the public to take an active participation in countering the mosquito-borne disease, through the 4-S strategy. (inquirer.net)
  • DHAKA, Jun 27 (IPS) - With the monsoon in Bangladesh, Rohingya refugee camps in Cox's Bazar have emerged as a dengue hotspot, with the mosquito-borne disease continuing to spread among the stateless refugees. (globalissues.org)
  • In 2012, Sanofi Pasteur was racing to develop a vaccine against dengue, a mosquito-borne disease, and was evaluating this product in a Phase IIb trial conducted with school children in Thailand. (hbs.edu)
  • Villagers in Kampong Cham - one of the hardest-hit provinces for dengue fever - have a high understanding of the mosquito-borne disease and how to prevent it, but they are not applying what they know to avoid becoming infected, a study has found. (phnompenhpost.com)
  • Dengue can cause a high fever, severe headaches, severe pain behind the eyes, rash and joint, muscle or bone pain. (eurekalert.org)
  • It happens due to water collection… If you change your habit of collecting fresh water in your house, we can eradicate dengue. (thehindu.com)
  • Coma explained that the measure will be in effect for three months and entails the implementation of fumigations to eradicate the mosquito that transmits dengue. (ticotimes.net)
  • As a result, the National Dengue Control Unit said it had launched a special two-day programme, starting Friday, to eradicate dengue breeding grounds in eight districts, including the north and east, which were identified as the most vulnerable districts. (xinhuanet.com)
  • Describe current dengue epidemiology and the populations who are at greatest risk for dengue and severe dengue in the United States. (cdc.gov)
  • In 2019, the Food and Drug Administration (FDA) approved a vaccine for children ages 9-16 years who have had dengue in the past and live in areas where dengue is common. (medicalnewstoday.com)