Dengue

Dengue Virus

Severe Dengue

Dengue Vaccines

Aedes

Insect Vectors

Antibodies, Viral

Culicidae

Thailand

Nicaragua

Antibody-Dependent Enhancement

Viral Nonstructural Proteins

Disease Outbreaks

Vietnam

Flavivirus

Mosquito Control

Serotyping

Immunoglobulin M

Puerto Rico

Disease Vectors

Travel

Brazil

Enzyme-Linked Immunosorbent Assay

RNA, Viral

Americas

Viral Envelope Proteins

Sri Lanka

Cuba

Rain

Antigens, Viral

Polynesia

Singapore

Dengue fever

Dengue vaccine

Dengue virus

Dengue Dengue Dengue!

Dengue Fever (band)

Dengue fever outbreaks

Dengue fever (disambiguation)

Discovering Dengue Drugs - Together

2009 Bolivian dengue fever epidemic

2005 dengue outbreak in Singapore

2006 dengue outbreak in India

2019 dengue outbreak in Bangladesh

2015 dengue outbreak in Taiwan

Dengue pandemic in Sri Lanka

2006 dengue outbreak in Pakistan

2017 dengue outbreak in Peshawar

2019 dengue outbreak in Pakistan

2011 dengue outbreak in Pakistan

2019-2020 dengue fever epidemic

2013 dengue outbreak in Singapore

2020 dengue outbreak in Singapore

2019 Cook Islands dengue fever outbreak

2017 dengue outbreak in Sri Lanka

Nonsteroidal anti-inflammatory drug

Arbovirus

Tourniquet test

Tom Solomon (neurologist)

Tick-borne encephalitis virus

List of deprecated terms for diseases

Sanofi Pasteur

Fever62

• Neurological Complications of Dengue Fever. (nih.gov)
• The endemicity of dengue fever and dengue haemorrhagic fever (‎DHF)‎ in countries of the South-East Asia (‎SEA)‎ and the Western Pacific regions continues to rise. (who.int)
• The disease dengue fever transmitting the virus to a new host while blood feeding. (cdc.gov)
• During epidemics of dengue, attack rates may be bone fever, dandy fever, and 80%-90% in susceptible persons. (cdc.gov)
• Dengue fever is a short-dura- and are unaware of their situation. (cdc.gov)
• More than 2 billion of the dengue hemorrhagic fever (DHF) and dengue shock syn- approximately 6.5 billion inhabitants of this planet are at drome, so that having uncomplicated DF can presage hav- risk of acquiring dengue, and the World Health ing DHF (1). (cdc.gov)
• DHF is characterized by high fever, vascular perme- cases of dengue infection worldwide every year" (avail- ability, bleeding, enlargement of the liver, and circulatory able from http://www.who.int/mediacentre/factsheets/ failure (dengue shock syndrome). (cdc.gov)
• Either there cases, signs and symptoms subside after the fever subsides, are 50 million dengue infections (some with illness, some but in severe cases the patient's condition suddenly deteri- not) or there are 50 million people sick with dengue each orates, body temperature decreases, and the circulatory year. (cdc.gov)
• Dengue fever usually starts with a fever, joint pain, rash and nausea. (nih.gov)
• Without treatment, the virus can cause damage to blood and lymph vessels and lead to dengue hemorrhagic fever, which is marked by difficulty breathing, bruising and bleeding from the nose, gums or under the skin. (nih.gov)
• Dengue fever usually is a self-limited illness. (medscape.com)
• There is no specific antiviral treatment available for dengue fever. (medscape.com)
• Patients with known or suspected dengue fever should have their platelet count and hematocrit measured daily from the third day of illness until 1-2 days after defervescence. (medscape.com)
• Patients who develop signs of dengue hemorrhagic fever warrant closer observation. (medscape.com)
• Exercise caution when placing intravascular catheters because of the increased bleeding complications of dengue hemorrhagic fever. (medscape.com)
• Dengue and dengue hemorrhagic fever (DHF) result from infection by any of four serotypes of dengue viruses. (cdc.gov)
• An outbreak of dengue fever on a small island chain in the middle of the Pacific. (cdc.gov)
• I often get asked about mosquito-borne dengue fever in the context of climate change. (cdc.gov)
• Dengue fever is an arbovirus transmitted by Aedes mosquitoes (both Ae . (who.int)
• Dengue haemorrhagic fever (DHF) is a potentially deadly complication that has become a leading cause of hospitalization and death among children in Asia. (who.int)
• There is no specific treatment for dengue, but appropriate medical care frequently saves the lives of patients with dengue haemorrhagic fever. (who.int)
• mosquito, one of the primary vectors for the transmission of dengue fever around the world. (who.int)
• Serological evidence of circulation of dengue fever has also been reported from Jordan. (who.int)
• Dengue is a mosquito-transmitted acute disease caused by any of four virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4) and is characterized by acute manifestations that can include fever, headache, myalgia, arthralgia, rash, nausea, and vomiting (1). (cdc.gov)
• On August 25, 1995, public health authorities in Mexico notified the Texas Department of Health (TDH) of an ongoing outbreak of dengue fever in the state of Tamaulipas, which borders south Texas ( Figure_1 ). (cdc.gov)
• Dengue hemorrhagic fever (DHF) * was reported in 37 (1%) of these cases. (cdc.gov)
• This syndrome is termed severe dengue (also known as dengue hemorrhagic fever and dengue shock syndrome). (medscape.com)
• Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. (medscape.com)
• Dengue should be suspected in individuals who present with high fever (104°F/40°C), retro-orbital headache, muscle and joint pain, nausea, lymphadenopathy, vomiting, and rash and who have traveled within 2 weeks of symptom onset to an area where appropriate vectors are present and dengue transmission may be occurring. (medscape.com)
• The initial phase of severe dengue is similar to that of dengue fever and other febrile viral illnesses. (medscape.com)
• Dengue : breakbone fever : a major unpublicized killer disease / Stephen Whitehead and Anna Durbin. (nih.gov)
• They were [each and every one of them] diagnosed with Dengue Fever. (ambergriscaye.com)
• Dengue fever is passed on only by a particlular mosquito. (ambergriscaye.com)
• I read an article somewhere that showed the statistics on Dengue fever. (ambergriscaye.com)
• Dengue fever is present in Belize, but it is fairly uncommon compared with most of the rest of Central America. (ambergriscaye.com)
• Dengue can cause hemorrhagic fever and infects an estimated 100 to 400 million people a year, although over 80 percent of cases are mild or asymptomatic, according to the World Health Organization. (hindustantimes.com)
• But neither option is yet close to eradicating dengue, and Aedes aegypti mosquitoes carry other diseases, including zika and yellow fever. (hindustantimes.com)
• Each year an estimated 390 million people worldwide are infected with dengue fever. (ticotimes.net)
• It was more effective - 88.5 percent - in preventing the more severe and lethal form of dengue, known as hemorrhagic fever. (ticotimes.net)
• In China's Yunnan province, a total of 102 cases of dengue fever have been reported. (medindia.net)
• A scientist has confirmed that Cuba is testing a recombinant vaccine against dengue fever on animals. (medindia.net)
• Health officials in Guwahati, Assam, are reporting a new outbreak of dengue fever, which has so far claimed three lives over the last eight days while many more have been hospitalized. (medindia.net)
• Colombian authorities expressed concerns on Monday that the spread of dengue fever could become an epidemic in the rural regions along its borders. (colombiareports.com)
• We raised the possibility of signing a bilateral agreement [with Ecuador] that lets us conduct activities together in order to confront dengue fever in the rural border areas, and carry out activities of education, prevention, diagnostics, and treatment. (colombiareports.com)
• The most recent report from the National Health Institute in Colombia shows that in the last year, eighteen people have died and another 15,000 have been infected by dengue fever in the country. (colombiareports.com)
• A state of emergency was declared in Cali several weeks ago after an outbreak of dengue fever killed at least nine people there. (colombiareports.com)
• Dengue fever is a mosquito-born, life-threatening disease similar to malaria, which occurs widely in tropical regions of the world. (colombiareports.com)
• The WHO estimate that dengue fever is "now endemic in more than 100 countries. (colombiareports.com)
• An epidemic of hemorrhagic dengue fever has struck the New Caledonia archipelago. (stanford.edu)
• Genetically engineered mosquitoes developed by British biotech firm Oxitec as an approach to controlling dengue fever have been caught up in controversy since 6,000 of them were deliberately released to an uninhabited forest in Malaysia in a trial in December 2010. (scientificamerican.com)
• About two-fifths of the world's population are at risk of contracting dengue fever. (scientificamerican.com)
• Dr. Suresh Singh Naruka, senior consultant (ENT), Indraprastha Apollo Hospitals, who is leading the treatment of the patient, said, 'A rare case of black fungus (mucormycosis) came into our view when the patient came to the hospital, reporting a sudden loss of vision in one eye post dengue fever. (thehindu.com)
• Dengue is accompanied with high fever and therefore, doctors feel that people might suspect that they have contracted COVID-19. (thehindu.com)
• Bangkok - Up to 10,446 cases of dengue fever infection have been recorded in Thailand since January 1 of this year with 15 deaths so far. (pattayamail.com)
• Aedes aegypti, a particularly aggressive mosquito, known for carrying dengue and yellow fever, is spotted in California. (medicaldaily.com)
• Aedes aegypti, the species of mosquito that transmits deadly tropical diseases including yellow fever and the dengue virus, has made its way through California's Central Valley to the Bay Area this year. (medicaldaily.com)
• MANILA, Philippines-The Department of Health (DOH) on Friday urged the public to practice what it called the "4 o'clock habit" to help bring down cases of the deadly dengue fever, which is expected to surge during the rainy season. (inquirer.net)
• According to the DOH, efforts were in place to bring down cases of dengue in the country but Visayas and Mindanao should brace for a higher number of cases this year, especially in August and September, when the dengue fever peaks. (inquirer.net)
• Immunochemistry of the dengue viruses, 199-219 In: D. J. Gubler and G. Kuno (eds), Dengue and dengue hemorrhagic fever. (scirp.org)
• Dengue fever infections dropped dramatically in an Indonesian study where a bacteria was introduced into disease-carrying mosquitoes, offering hope in the battle against an illness that sickens millions annually around the world. (aljazeera.com)
• Like Zika, yellow fever and West Nile viruses, dengue belongs to a group of mosquito-borne viruses that circulate in many tropical countries. (uvm.edu)
• However, without effective treatment and a safe licensed vaccine, dengue infection can lead to debilitating illnesses, including severe pain and hemorrhagic fever. (uvm.edu)

Mosquitoes12

• 2001, 600,000 cases of dengue were reported in the ample time for mosquitoes, often many mosquitoes, to Americas, of which 15,000 were cases of DHF, more than feed and become infected. (cdc.gov)
• I traveled there to assist the RMI Ministry of Health and Human Services vector staff in spraying larvicides and adulticides against mosquitoes around dengue cases in Majuro. (nih.gov)
• The virus that causes dengue is transmitted by mosquitoes. (nih.gov)
• Infected humans are the main carriers and multipliers of the virus, serving a source of the virus for uninfected Aedes aegypti mosquitoes which maintain the urban dengue transmission cycle. (who.int)
• At present, the only method of controlling or preventing dengue virus transmission is to combat the vector mosquitoes using environmental management and chemical methods. (who.int)
• Click to expand Dengue is a mosquito-borne viral disease that is transmitted between humans by Aedes mosquitoes. (who.int)
• Mosquitoes that transmit dengue and other viruses have evolved growing resistance to insecticides in parts of Asia, and novel ways to control them are desperately needed, new research warns. (hindustantimes.com)
• Several dengue vaccines have been developed, and researchers have also used a bacteria that sterilises mosquitoes to tackle the virus. (hindustantimes.com)
• When the clock strikes 4 p.m., assigned teams must "look" for the breeding sites of dengue-carrying mosquitoes and carry out systematic "search and destroy activities to eliminate them. (inquirer.net)
• But while climate change is threatening to increase the spread of dengue worldwide by expanding the range of the mosquitoes that carry the virus, the disease has already found an especially fertile breeding ground in Honduras, for reasons that go beyond the environment. (sej.org)
• Results of the three-year study, published in the New England Journal of Medicine this week, found that infecting dengue-carrying mosquitoes with a harmless bacteria called Wolbachia led to a 77 percent drop in human cases. (aljazeera.com)
• Wolbachia suppresses the ability of the virus to replicate in dengue-carrying Aedes aegypti mosquitoes and cause infections when they bite humans. (aljazeera.com)

Risk of dengue2

• Almost half of the world's population, about 4 billion people, live in areas with a risk of dengue . (cdc.gov)
• Of primary concern is the risk of dengue transmission within the continental United States. (cdc.gov)

Infection23

• Approximately 100 million people get sick from infection, and 40,000 die from severe dengue. (cdc.gov)
• NIAID-supported investigators are pursuing several approaches to treat dengue infection. (nih.gov)
• Dengue infection: Global importance, immunopathology and management. (nih.gov)
• Dengue is a viral infection . (nih.gov)
• [ 84 ] The Novartis Institute for Tropical Diseases (NITD) in Singapore is carrying out research to find inhibitors of dengue viral target proteins to reduce the viral load during active infection. (medscape.com)
• There is good evidence that sequential infection with the different serotypes of dengue virus increases the risk of more severe disease that can result in shock syndrome and death. (who.int)
• The infection causes flu-like illness, and occasionally develops into a potentially lethal complication called severe dengue. (who.int)
• Although recovery from infection by one of the serotypes provides lifelong immunity against it, cross-immunity is only partial and subsequent infections by other serotypes increase the risk of developing severe dengue. (who.int)
• This infection total is more than three times the dengue burden estimate of the World Health Organization 2 . (nature.com)
• Stratification of our estimates by country allows comparison with national dengue reporting, after taking into account the probability of an apparent infection being formally reported. (nature.com)
• These new risk maps and infection estimates provide novel insights into the global, regional and national public health burden imposed by dengue. (nature.com)
• Dengue infection was laboratory-diagnosed by positive immunoglobulin M (IgM)-capture enzyme-linked immunosorbent assay (ELISA) (578 cases) and viral isolation (64 cases). (cdc.gov)
• Because of the reported outbreak in Tamaulipas, on August 25, 1995, TDH issued a dengue alert memorandum by facsimile to all local health departments, infection-control practitioners, and infectious disease physicians in south Texas. (cdc.gov)
• of these, 23 had virologic or serologic evidence of dengue infection. (cdc.gov)
• A small percentage of persons who have previously been infected by one dengue serotype develop bleeding and endothelial leak upon infection with another dengue serotype. (medscape.com)
• Director-General of the Department of Disease Control (DDC), Dr. Suwanchai Wattanayingcharoenchai, elaborated that most cases of dengue infection were among citizens aged between 15 and 24, followed by those aged 10-14 and then 25-34. (pattayamail.com)
• An estimated 74,000 to 75,000 people are expected to contract dengue this year and more deaths are likely now that infection has increased among younger individuals. (pattayamail.com)
• Thus, in order to characterize the role of glycoprotein E in the pathogenesis of dengue virus infection, we first used network servers (http://bio.dfci. (scirp.org)
• In statements to Granma newspaper, Eduardo Martínez, president of the Biotechnological and Pharmaceutical Industries Business Group, argued that such a system would make it possible to determine, upon the appearance of the first symptoms, whether it is dengue or a second infection. (plenglish.com)
• Investigators in UVM's Vaccine Testing Center and Center for Translational Global Infectious Disease Research (TGIR) have uncovered details of the human immune response to infection with dengue - a close "cousin" of the Zika virus - which 40 percent of the global population is at risk for contracting. (uvm.edu)
• Study findings, reported recently in the Lancet 's open-access journal EBioMedicine , illustrate new critical information that could provide much-needed help to evaluating dengue vaccine formulations and assist with advancing safe and efficacious candidate vaccines to help combat the most important mosquito-borne viral infection in our time. (uvm.edu)
• One of the challenges of dengue infection is that it can be caused by one of four versions - or serotypes - of the virus, which are numbered dengue 1 to 4. (uvm.edu)
• In this study, co-led by Huy Tu, a fifth-year Ph.D. candidate in the Cellular and Molecular Biomedical Sciences program, the group defined the evolution of the antibody response in dengue infection in a controlled human model where subjects were treated with a weakened version of the virus. (uvm.edu)

Form of dengue2

• The mild form of dengue is a serious annoyance and shock and die within a day, or quickly recover, if volume often is painful for those with it. (cdc.gov)
• 1) Outbreaks of the more severe form of dengue, DHF, occurred in Cuba in 1981 (2) and in Venezuela in 1989. (cdc.gov)

Aedes3

• For example, the entire genome sequence of the Aedes aegypti mosquito, the main carrier of dengue virus, has been decoded and is available to qualified researchers. (nih.gov)
• 10) Adding to the concern of indigenous dengue transmission is the recent establishment in the United States of another known dengue vector, Aedes albopictus, which was probably imported in shipments of tires from Asia. (cdc.gov)
• Because of the year-round presence of the Aedes aegypti mosquito (a major vector for dengue) in southernmost Texas and the frequent movement of persons across the U.S.-Mexico border, the outbreak in adjacent Tamaulipas suggested an increased potential for imported and autochthonous cases in Texas, as had occurred during 1980 and 1986 (2). (cdc.gov)

Treat dengue2

• There is no specific medicine to treat dengue. (nih.gov)
• Havana, Mar 21 (Prensa Latina) Cuba´s vaccine candidate to treat dengue has a safe technological platform, as informed by the Center for Genetic Engineering and Biotechnology (CIGB). (plenglish.com)

Chikungunya3

• Mosquito-borne diseases (MBD) outbreaks have increased drastically over the last decade with dengue, then Zika and chikungunya, and dengue again, with the latest outbreak having begun in 2019 and continuing over much of the period since. (nih.gov)
• Dengue-like epidemics occurred in Egypt and on Java in 1779, but these may actually have been caused by chikungunya virus. (cdc.gov)
• Mosquito-borne diseases like dengue, malaria and chikungunya cases expected to ramp up after the recent rains. (medindia.net)

Viruses9

• Dengue is caused by one of any of four related viruses: Dengue virus 1, 2, 3, and 4. (cdc.gov)
• Although, it is not usu- by other names) can be caused ally recognized, more than half the people who are infect- by any of 4 viruses within the ed with a dengue virus may be asymptomatic, which virus family Flaviviridae , would indicate a substantial underreporting of infections. (cdc.gov)
• Through a mechanism known as immune with imported cases essentially everywhere tourists, busi- enhancement, sequential infections with certain dengue ness people, and military personnel travel, whether dengue viruses set the stage for a far more serious complication, is recognized there or not. (cdc.gov)
• The mosquito acquires the these countries are in Southeast Asia and the Western virus by taking a blood meal from an infected human, the Pacific, but with the worldwide spread of all dengue types, principal amplifying host for these viruses, or from an this disease threatens residents in tropical and subtropical infected monkey. (cdc.gov)
• A vaccine with varying level of effectiveness for each of the 4 dengue viruses is available (and others are being researched), and WHO has issued a conditional recommendation on the use of the vaccine for highly endemic areas. (who.int)
• 1990) The dengue viruses. (scirp.org)
• G. J. Chang, Molecular biology of dengue viruses, 175-198 In: D. J. Gubler, G. Kuno (eds. (scirp.org)
• We are currently assessing a tetravalent candidate, based on proteins of the four dengue viruses," CIGB added. (plenglish.com)
• Dengue virus is a member of the Flavivirus genus of viruses and can result in severe febrile illness. (nih.gov)

Severe14

• What are the symptoms of dengue and severe dengue? (nih.gov)
• Severe dengue is a serious form of the illness. (nih.gov)
• About 1 in 20 people who get sick with dengue will develop severe dengue. (nih.gov)
• People are more likely to develop severe dengue if they have had dengue before, are pregnant, or are infants. (nih.gov)
• Watch for signs and symptoms of severe dengue. (nih.gov)
• Severe dengue often requires care at a hospital. (nih.gov)
• Management of severe dengue requires careful attention to fluid management and proactive treatment of hemorrhage. (medscape.com)
• Although the incidence of hemorrhagic dengue in United States travelers abroad is low,(13,15) clinicians in this country may encounter severe cases of dengue, particularly among immigrants from areas with a high incidence of DHF. (cdc.gov)
• 14,18,19) Nevertheless through the first half of the 20th century, dengue was generally described as a self-limited, nonfatal febrile illness, with occasional hemorrhagic manifestations such as petechiae, epistaxis, gingival bleeding and menorrhagia, that only rarely resulted in more severe or fatal outcomes. (cdc.gov)
• Severe dengue is a leading cause of serious illness and death among children in some Asian and Latin American countries. (who.int)
• Occasionally it develops into a potentially lethal complication called severe dengue. (who.int)
• Reports of dengue and severe dengue epidemics in the Region started in 1998 and have increased in frequency and spread ever since, with outbreaks occurring in Djibouti, Egypt, Oman, Pakistan, Saudi Arabia, Somalia, Sudan, and Yemen. (who.int)
• Describe current dengue epidemiology and the populations who are at greatest risk for dengue and severe dengue in the United States. (cdc.gov)
• Recognize the three phases (febrile, critical, convalescent) and the three severity levels of symptomatic dengue (dengue, dengue with warning signs, severe dengue) based on a patient's clinical and laboratory findings. (cdc.gov)

Patients with dengue1

• Admission to an intensive care unit is indicated for patients with dengue shock syndrome. (medscape.com)

Outbreak2

• My first assignment as the medical entomologist for the U.S.-Affiliated Pacific Islands (USAPIs) was to respond to the dengue outbreak in the Republic of the Marshall Islands (RMI). (nih.gov)
• CHOLOMA, Honduras - More than 400 people died this year as one of the worst dengue epidemics on record swept through Central America - a type of outbreak that some scientists and public health officials are warning is likely to become more frequent and more widespread because of climate change. (sej.org)

Serotypes of dengue virus1

• All the 4 serotypes of dengue virus have been known to have circulated in the Region during these outbreaks. (who.int)

Epidemics5

• One of the earliest, if not the first, dengue epidemics described in the medical literature occurred in Philadelphia in 1780. (cdc.gov)
• 5-7) Dengue epidemics were reported in various parts of the south- eastern United States through the 19th and 20th centuries, (6) most recently in Louisiana in 1945. (cdc.gov)
• 7) Dengue or dengue-like epidemics were reported through- out the 19th and early 20th centuries in the Americas, southern Europe, North Africa, the Middle East, Asia and Australia and on various islands in the Indian Ocean, South and Central Pacific and the Caribbean. (cdc.gov)
• 7) Deaths occurred during dengue epidemics in Australia in 1897 and in Greece in 1928, when over 1000 deaths were reported. (cdc.gov)
• 17) Hemorrhagic manifestations, including gastrointestinal hemorrhage, were described during dengue epidemics in Texas and Louisiana in 1922. (cdc.gov)

World Health Organ5

• The World Health Organization (WHO) has provided a number of free publications about dengue . (medscape.com)
• From 1981 through 1986, 796 386 cases of DHF and 9774 deaths caused by dengue were reported to the World Health Organization (WHO) from countries in Southeast Asia. (cdc.gov)
• Presenters will also review dengue clinical classification, diagnosis, and general treatment guidelines based on World Health Organization and Centers for Disease Control and Prevention recommendations. (cdc.gov)
• Between 2008 and 2013 the number of reported dengue cases more than doubled, according to the World Health Organization, and the disease is spreading beyond its usual tropical environment. (ticotimes.net)
• According to the World Health Organization (WHO), two-fifths of the world's population, or 2.5 billion people, are at risk of the disease, and that "there may be 50 million dengue infections worldwide every year. (colombiareports.com)

Vaccines1

• Dengue Vaccines: An Update. (nih.gov)

Outbreaks3

• Other USAPI jurisdictions also fought dengue outbreaks during this time, including Guam, Palau, and the Federated States of Micronesia (FSM). (nih.gov)
• 9) Outbreaks of indigenous dengue transmission occurred in Texas in 1980 and again in 1986. (cdc.gov)
• While dengue has long been present in Costa Rica, there have been significant outbreaks in recent years. (ticotimes.net)

20161

• 2016)‎. Dengue. (who.int)

Tagged dengue virus1

• The researchers tagged dengue virus and cell membranes with fluorescent probes that glow when the virus and membranes fuse. (nih.gov)

20231

• A new system for rapid diagnosis of dengue should be available in 2023. (plenglish.com)

Flavivirus1

• 2002) Structure of dengue virus: implications for flavivirus organization, matu--ration, and fusion. (scirp.org)

Burden of Dengue1

• We then pair the resulting risk map with detailed longitudinal information from dengue cohort studies and population surfaces to infer the public health burden of dengue in 2010. (nature.com)

Treatment of dengue2

• These free NIAID databases provide scientists with the means to analyze and extract vast amount of genomic data, and advances the understanding and treatment of dengue disease. (nih.gov)
• Single-dose methylprednisolone showed no mortality benefit in the treatment of dengue shock syndrome in a prospective, randomized, double-blind, placebo-controlled trial. (medscape.com)

Distribution of dengue2

• Persistent Emergence of Dengue geographic distribution of dengue spreading, but the seri- as well as molecular approaches will soon be available and ousness of its complications is being recognized (available hold out promise of tools we need to eliminate or eradicate from http://www.cdc.gov/search.do?action=search&query this scourge. (cdc.gov)
• Here we undertake an exhaustive assembly of known records of dengue occurrence worldwide, and use a formal modelling framework to map the global distribution of dengue risk. (nature.com)

Transmission of dengue1

• In Tamaulipas, transmission of dengue ended by late December 1995. (cdc.gov)

Virus18

• For this reason, a person can be infected with a dengue virus as many as four times in his or her lifetime. (cdc.gov)
• KSF 103 methanolic extract ( Streptomyces KSF 103 ME), which consists of a number of potential antiviral compounds, were investigated against dengue virus serotype 2 (DENV-2). (nih.gov)
• Researchers have discovered a key step in how the dengue virus infects a cell. (nih.gov)
• To infect a cell, the dengue virus initially binds to the cell surface. (nih.gov)
• However, attempts to fuse dengue virus under either of these conditions have been unsuccessful. (nih.gov)
• A research team led by Dr. Leonid V. Chernomordik at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) set out to investigate how the dengue virus fuses with its target membranes. (nih.gov)
• The researchers discovered that 2 conditions are essential for dengue virus fusion. (nih.gov)
• We spent several years trying to understand how the dengue virus fuses with its target membrane," Chernomordik says. (nih.gov)
• The vaccine, made by French pharmaceutical company Sanofi, is the first of several in development and is designed to help prevent all four strains of the dengue virus. (ticotimes.net)
• The actions protect against dengue, the Zika virus and other mosquito borne infections. (pattayamail.com)
• Quantitative synthetic RNA for Dengue virus type 1 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. (atcc.org)
• To download a certificate of analysis for Quantitative Synthetic RNA from Dengue virus type 1 ( VR-3228SD ), enter the lot number exactly as it appears on your product label or packing slip. (atcc.org)
• The certificate of analysis for that lot of Quantitative Synthetic RNA from Dengue virus type 1 ( VR-3228SD ) is not currently available online. (atcc.org)
• The major envelope glycoprotein E of dengue (DEN) virus plays a central role in the biology of flaviviruses. (scirp.org)
• In our study, the sequence at 281-295 amino acid (aa) for den-gue virus type 1 HAWAII strain and the sequence at 345-359, 383-397 for dengue virus type 2 NGC strain were predicted as the more prevalent epi-topes by using multiple parameters and different analysis softwares, respectively. (scirp.org)
• 2003) A ligand-binding pockets in the dengue virus envelop glycoprotein. (scirp.org)
• Here we show for the first time that the uncharacterized protein FLJ11286, which we refer to as IRAV, is induced by dengue in an interferon dependent manner and displays antiviral activity against dengue virus. (nih.gov)
• Furthermore, we show that overexpression of IRAV results in a diminished stability of dengue virus mRNA, suggesting a role for IRAV in mediating the stability of viral RNA. (nih.gov)

Fight dengue1

• The vaccine candidate to fight dengue is based on recombinant proteins: a safe technological platform," CIGB tweeted. (plenglish.com)

Endemic dengue1

• Of the 29 patients with laboratory-diagnosed dengue, eight reported recent travel to areas with endemic dengue outside Mexico. (cdc.gov)

Prevention6

• Dengue prevention and control depends on effective vector control measures. (who.int)
• Packets of information about dengue prevention were mailed to 13,000 primary-care and emergency department physicians throughout the state. (cdc.gov)
• Community education efforts included a press release advising the public about the threat of dengue and recommendations for preventing mosquito exposure, the distribution of informational material on dengue prevention and the mosquito life cycle (6000 posters and 200,000 pamphlets in English and Spanish). (cdc.gov)
• I believe that to get Dengue you have to actually be bitten by the infected [carrier] mosquito, So a good dose of mosquito prevention should keep the worries down. (ambergriscaye.com)
• Though Dengvaxia is now the only proven form of medical prevention for dengue, it is still only partially effective. (ticotimes.net)
• Despite the vaccine's pitfalls, the need for dengue prevention is growing worldwide. (ticotimes.net)

Vectors1

• Piles of old car tires gathered on Majuro for building materials to construct a seawall for protection against sea-level rise and creating major breeding sites for dengue mosquito vectors. (nih.gov)

Complications1

• Tragically, DHF is a leading cause complications, dengue diagnosis, and dengue epidemiolo- of hospitalization and death of children in several Asian gy. (cdc.gov)

Deaths3

• According to a civic report on vector-borne diseases released on Monday, nine deaths and a total of 2,708 dengue cases have been recorded this season till November 6, which is the highest count since 2017 for the same period. (thehindu.com)
• From January to June 8 this year, the National Epidemiology Center has so far logged in a total of 42,207 cases and 193 deaths due to dengue. (inquirer.net)
• In Honduras, which accounted for more than 40 percent of the dengue deaths in Central America this year, according to the Pan American Health Organization, the effects of climate change have been compounded by government dysfunction, political tumult and public apathy. (sej.org)

Infectious Diseases2

• This issue of Emerging Infectious Diseases includes require hospitalization each year, a substantial proportion some very interesting reports on dengue and its clinical of whom are children. (cdc.gov)
• Dengue Branch and the Division of Vector Borne Infectious Diseases, Centers for Disease Control, CID, Fort Collins, CO. Duane J. Gubler, Sc.D and Edward B. Hayes, MD. (cdc.gov)

Illness4

• Dengue is often a leading cause of illness in areas with risk. (cdc.gov)
• However, during the first week of July 1996, cases of dengue-like illness were reported in Tampico. (cdc.gov)
• TDH conducted active surveillance for dengue-like illness through telephone calls and personal visits to area hospitals and clinical and reference laboratories. (cdc.gov)
• Dengue is the most common and important arthropod-borne viral (arboviral) illness in humans. (medscape.com)

Infections2

• Using cartographic approaches, we estimate there to be 390 million (95% credible interval 284-528) dengue infections per year, of which 96 million (67-136) manifest apparently (any level of disease severity). (nature.com)
• It is rarest of the rare to see mucormycosis as a post-recovery complication in a dengue patient as this condition is generally seen in people who have a history of diabetes, compromised immunity and various other infections. (thehindu.com)

Malaria5

• Recent studies have revealed that dengue, a disease that is well recognized in Asia and the Americas, may be commonly misdiagnosed as malaria in Africa. (cdc.gov)
• The transmission of mosquito-borne diseases like malaria and dengue can now be tracked using mobile health technology and software. (nih.gov)
• Dengue and malaria cases have increased in the national capital and Gurugram has increased screening at the border to curb the rising cases. (medindia.net)
• The Colombian authorities have been concerned for several months now about the spread of mosquito-transmitted diseases such as dengue and malaria, following an exceptionally hot and dry season. (colombiareports.com)
• The dengue mosquito larvae breed in clear, standing water, while those of malaria thrive even in dirty water. (thehindu.com)

Incidence2

• The global incidence of dengue has grown dramatically in recent decades. (who.int)
• We have evidence our Wolbachia method is safe, sustainable and dramatically reduces incidence of dengue. (aljazeera.com)

Proteins2

• This information may help investigators identify the mosquito proteins that are essential to support dengue replication and transmission, and allow them eliminate the proteins in transgenic insects. (nih.gov)
• IRAV associates with dengue and host proteins, and interacts with MOV10. (nih.gov)

Vaccine Candidate1

• Three-year Efficacy and Safety of Takeda's Dengue Vaccine Candidate (TAK-003). (nih.gov)

Centers2

• 13-15) From 1980 through 1989, 1457 suspected and 276 confirmed cases of dengue in the continental United States and Hawaii were reported to the Centers for Disease Control. (cdc.gov)
• Under the agreement, the DILG is tasked to lead all local government units to implement the campaign dubbed "Aksyon Barangay Kontra Dengue," particularly in high-risk communities such as urban centers with poor environmental management of household waste. (inquirer.net)

Symptoms2

• Dengue symptoms usually last 2-7 days. (medscape.com)
• Mucormycosis post dengue is a new observation and hence, patients with a recent history of dengue should remain actively updated about their health and consult a healthcare expert immediately after noticing any new symptoms, doctors at the Apollo hospital said. (thehindu.com)

Symptomatic1

• On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). (medscape.com)

Syndrome1

• Children younger than 15 years who have dengue usually have a nonspecific febrile syndrome, which may be accompanied by a maculopapular rash. (medscape.com)

Cases15

• Hundreds of thousands of cases of dengue and DHF are reported each year in tropical regions of the Americas, Africa, Asia and Oceania. (cdc.gov)
• From 1980 through 1987, 879 632 cases of dengue were reported to the Pan American Health Organization from countries in the American region. (cdc.gov)
• The second reason dengue should concern health care providers in this country is the potential for encountering cases of dengue among travelers arriving from dengue-endemic areas. (cdc.gov)
• Mosquito control teams equipped with cell phones can visit homes where dengue cases have occurred and immediately send data back from the field or save it to a local database. (nih.gov)
• In response to the notification from Mexico, TDH intensified surveillance efforts for dengue, resulting in identification of 29 laboratory-diagnosed cases in Texas residents, including seven persons with no history of travel outside the state. (cdc.gov)
• During July-December 1995, health authorities in Tamaulipas (1994 population: 2,459,087) reported 4758 suspected cases of dengue to health authorities in Mexico. (cdc.gov)
• In 2013, a dengue epidemic produced more cases than ever in Costa Rica, infecting nearly 50,000 people. (ticotimes.net)
• An official revealed that at least 93 new dengue cases were reported in Odisha, taking the total number of affected people to 2,593 since June. (medindia.net)
• Health ministry figures show that India has recorded 15,893 dengue cases in 2013, a sharp increase from last year. (medindia.net)
• Globally, about three quarters of a million fewer global dengue cases have been occurred in 2020. (medindia.net)
• The case reported at the Apollo hospital in south Delhi comes amid a huge spike in the number of dengue cases in the national capital. (thehindu.com)
• In a statement issued on Saturday, the Apollo hospital said, 'A 49-year-old male has been reported to be one the rare cases of post-dengue mucormycosis by a team of doctors at the hospital. (thehindu.com)
• Calabarzon registered 4,742 cases while Davao registered a 30-percent increase with 4,364 incidents of dengue. (inquirer.net)
• Previous trials involving Wolbachia - commonly found in fruit flies and other insects - also showed positive results in reducing dengue cases, researchers said. (aljazeera.com)
• Dengue is the most rapidly spreading mosquito-borne disease in the world with more than 50 million cases globally every year, including about eight million in Indonesia. (aljazeera.com)

19962

• This report summarizes results of dengue surveillance in the U.S.-Mexico border area during 1995-1996. (cdc.gov)
• I was bitten and caught Dengue in 1996 in Ambergris Caye. (ambergriscaye.com)

NIAID2

• In one NIAID-funded contract, researchers evaluated about 7,500 antiviral compounds in vitro to test their efficacy against dengue. (nih.gov)
• NIAID also provides the scientific community with the genetic sequence data from several hundreds of viral strains that have been isolated from dengue-infected people. (nih.gov)

Clinical2

• The early history of dengue is clouded by the similarity of its clinical picture to that of other febrile illnesses. (cdc.gov)
• In clinical trials, the vaccine reduced the chance of contracting dengue by 60 percent. (ticotimes.net)

Researchers1

• The new mobile health platform, which makes use of the existing communications infrastructure in Mexico, gives dengue researchers near real-time monitoring capacity as well as the ability to rapidly transmit findings. (nih.gov)

Severity1

• Identify the indicated treatment group (A, B, C), including hospital admission and intravenous fluids management recommendations, based on dengue phase and severity. (cdc.gov)