Phosphocreatine: An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Creatine: An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Phosphates: Inorganic salts of phosphoric acid.Phosphorus Isotopes: Stable phosphorus atoms that have the same atomic number as the element phosphorus, but differ in atomic weight. P-31 is a stable phosphorus isotope.Creatine Kinase: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Creatine Kinase, BB Form: A form of creatine kinase found in the BRAIN.Adenosine Diphosphate: Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.Lactates: Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.Creatine Kinase, MM Form: An isoenzyme of creatine kinase found in the MUSCLE.Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Creatine Kinase, Mitochondrial Form: A form of creatine kinase found in the MITOCHONDRIA.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Oxidative Phosphorylation: Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.Glycolysis: A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.Mitochondria, Muscle: Mitochondria of skeletal and smooth muscle. It does not include myocardial mitochondria for which MITOCHONDRIA, HEART is available.Muscles: Contractile tissue that produces movement in animals.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Guanidinoacetate N-Methyltransferase: This enzyme catalyzes the last step of CREATINE biosynthesis by catalyzing the METHYLATION of guanidinoacetate to CREATINE.GlycogenAdenine NucleotidesAspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.Hypoxia, Brain: A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Muscle Fatigue: A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.Adenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.Inosine Monophosphate: Inosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.Dichloroacetic Acid: A derivative of ACETIC ACID that contains two CHLORINE atoms attached to its methyl group.Physical Exertion: Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.Phosphorus Compounds: Inorganic compounds that contain phosphorus as an integral part of the molecule.Ergometry: Any method of measuring the amount of work done by an organism, usually during PHYSICAL EXERTION. Ergometry also includes measures of power. Some instruments used in these determinations include the hand crank and the bicycle ergometer.Kinetics: The rate dynamics in chemical or physical systems.Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Physical Conditioning, Human: Diet modification and physical exercise to improve the ability to carry out daily tasks and perform physical activities.Choline: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Brain Chemistry: Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.Glycerylphosphorylcholine: A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules.Iodoacetates: Iodinated derivatives of acetic acid. Iodoacetates are commonly used as alkylating sulfhydryl reagents and enzyme inhibitors in biochemical research.Isometric Contraction: Muscular contractions characterized by increase in tension without change in length.Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Heart: The hollow, muscular organ that maintains the circulation of the blood.Pyruvate Dehydrogenase Complex: A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)Rest: Freedom from activity.Dinitrofluorobenzene: Irritants and reagents for labeling terminal amino acid groups.Protons: Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Propionates: Derivatives of propionic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxyethane structure.Mitochondria, Heart: The mitochondria of the myocardium.Leg: The inferior part of the lower extremity between the KNEE and the ANKLE.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Physical Endurance: The time span between the beginning of physical activity by an individual and the termination because of exhaustion.Amidinotransferases: Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to acceptor. EC 2.1.4.PyruvatesAdenylate Kinase: An enzyme that catalyzes the phosphorylation of AMP to ADP in the presence of ATP or inorganic triphosphate. EC 2.7.4.3.Anoxia: Relatively complete absence of oxygen in one or more tissues.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Quadriceps Muscle: The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Creatine and phosphocreatine: with its major peak at 3.0 ppm, creatine marks metabolism of brain energy. Gradual loss of ... Acquiring an MRS scan is very similar to that of MRI with a few additional steps preceding data acquisition. These steps ...
In some experiments, the retention times of weak ion exchangers are just long enough to obtain desired data at a high ... The functions of these isoenzymes are to convert creatine, using ATP, into phosphocreatine expelling ADP. Mini columns were ... Control an IC system usually requires a chromatography data system (CDS). In addition to IC systems, some of these CDSs can ...
Mora B.; Narasimhan P.T.; Ross B.D.; Allman J.; Barker P. B. (1991). "P Saturation Transfer and Phosphocreatine Imaging in the ... He was known for his studies on quantum-mechanical interpretation of magnetic resonance data and his contributions in ... studies of the structure and properties of molecules were based on quantum-mechanical interpretation of magnetic resonance data ...
... it becomes the high-energy compound phosphocreatine.[4] Creatine conversion to phosphocreatine is catalyzed by creatine kinase ... Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ... Creatinine itself is produced[3] via a biological system involving creatine, phosphocreatine (also known as creatine phosphate ...
Pharmacological data isconsistent with dysfunction of dopamine in bipolar as some studies have reported hypersensitivity to ... Downregulation of genes encoding for mitochondrial subunits, decreased concentration of phosphocreatine, decreased brain pH, ... and individual MRI data". Neuroscience and Biobehavioral Reviews. 84: 162-170. doi:10.1016/j.neubiorev.2017.11.005. PMID ...
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ...
This allows more data to be drawn from the same specimen, increasing the reliability of the data, reducing the amount of sample ... "Safety (MSDS) data for glycine". The Physical and Theoretical Chemistry Laboratory Oxford University. 2005. Archived from the ... Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ... Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959. ...
The quick energy sources consist of the phosphocreatine (PCr) system, fast glycolysis, and adenylate kinase. All of these ... Once the information is gathered about a client, exercise physiologists must also be able to interpret the test data and decide ... This enzyme catalyzes a reaction that combines phosphocreatine and adenosine diphosphate (ADP) into ATP and creatine. This ... The data providing these formula hide a high variance: for men weighing 70 kg, measured BMR is between 50 and 110 W, and women ...
Please note that data for multi-racial Asian Americans has not yet been released by the US Census Bureau. ... He discovered the role of phosphocreatine and adenosine triphosphate (ATP) in muscular activity, which earned him an entry into ... "U.S. Census Bureau Delivers Illinois' 2010 Census Population Totals, Including First Look at Race and Hispanic Origin Data for ... "Profile of General Demographic Characteristics: Census 2000 Summary File 1 (SF 1) 100-Percent Data". United States Census ...
"The Determination of Phosphorus and the Discovery of Phosphocreatine and ATP: the Work of Fiske and SubbaRow".. ... Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ...
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ...
The discovery of phosphocreatine was reported by Grace and Philip Eggleton of the University of Cambridge[56] and separately by ... The concept of packet switching, a communications method in which discrete blocks of data (packets) are routed between nodes ... over data links, was first explored by Paul Baran in the early 1960s, and then independently a few years later by Donald Davies ...
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ...
Control an IC system usually requires a chromatography data system (CDS). In addition to IC systems, some of these CDSs can ... The functions of these isoenzymes are to convert creatine, using ATP, into phosphocreatine expelling ADP. Mini columns were ... In some experiments, the retention times of weak ion exchangers are just long enough to obtain desired data at a high ...
Conclusions: These data suggest that uMtCK is downregulated as prostate cancer progresses in correlation with a metabolic ... and phosphocreatine. However, little is known about its expression and function in human prostate cancer progression. ...
Talking biologically, Creatine is the energy storage itself in the form of Phosphocreatine in the muscles. This compound ... But the data recorded by the consumers have different things to reveal. ...
... phosphocreatine; UDPG = uridine diphosphoglucose; Glc = glucose; Lac = lactate. (C) shows data for lipid compounds. MUFA = ... A) displays data for soluble metabolites. Cho = choline; Cr = creatine GSH = glutathione; Lac = lactate. (B) displays data for ... Our data characterize the UPR in glioma cells and human tumors, and link the UPR to chemoresistance possibly via enhanced ... Tumors were extracted as described; 1H- and 31P-NMR spectra were obtained and quantified with data analyses conducted as ...
Molecular Sequence Data * Muscle, Skeletal / metabolism * Mutation, Missense* * Phosphates / metabolism * Phosphocreatine / ... These data strongly suggest that this molecular defect is the primary cause of the myopathy. ...
... results also provide the basis for estimating skeletal muscle fiber-type composition from noninvasive NMR spectroscopic data. ... Mammalian skeletal muscle fibers distinguished by contents of phosphocreatine, ATP, and Pi.. M J Kushmerick, T S Moerland, and ... We tested the proposition that muscle cell types have different contents of phosphocreatine (PCr), ATP, and Pi by 31P NMR ... Mammalian skeletal muscle fibers distinguished by contents of phosphocreatine, ATP, and Pi. ...
ATP + creatine = ADP + phosphocreatine. *KCRM_HUMAN,P06732. UniProtKB/Swiss-Prot Function: Reversibly catalyzes the transfer of ... No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CKM Gene ... No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ... No data available for CIViC summary , Tocris Summary , PharmGKB VIP Summary , fRNAdb sequence ontologies and piRNA Summary ...
Data adapted from Parolin et al., (1999). ATP = adenosine triphosphate; PCr = phosphocreatine. *Significantly different from ... Data adapted from Parolin et al., (1999). ATP = adenosine triphosphate; PCr = phosphocreatine. *Significantly different from ... Data adapted from Parolin et al., (1999). ATP = adenosine triphosphate; PCr = phosphocreatine. *Significantly different from ... Data estimated from video measurements and feature typical ranges across male and female athletes. All estimates within do not ...
The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The type of ... The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA ... Infocards are automatically generated based on industry data. What is an infocard? ... REACH registration dossiers have greater data requirements (support studies) than notifications under CLP. ...
154 Pages Report] Check for Discount on Global Phosphocreatine Market Professional Survey Report 2016 report by QYResearch ... 2.6 Manufacturing Process Analysis of Phosphocreatine 3 Technical Data and Manufacturing Plants Analysis of Phosphocreatine 3.1 ... 5.1 USA Phosphocreatine Market Analysis 5.1.1 USA Phosphocreatine Market Overview 5.1.2 USA 2011-2016E Phosphocreatine Local ... 5.3 UK Phosphocreatine Market Analysis 5.3.1 UK Phosphocreatine Market Overview 5.3.2 UK 2011-2016E Phosphocreatine Local ...
Scientists are optimistic about the research, but do not have conclusive data to recommend these supplements to treat PD. ... It increases levels of phosphocreatine (an energy source in muscle and brain). The National Institute of Neurological Disorders ... it is important to remember that there is not sufficient scientific data to recommend them for Parkinsons. OTC medications ...
From design of experiments, through data processing, to data analysis, chemometrics tools are used to design, process, ... Phosphocreatine/creatine and citrate were identified at higher concentrations after consumption of EHB. Beverage consumption (i ... and looks for the common dimensions underlying the different data tables, or data blocks, generated by the ANOVA-step of the ... visualize, explore and analyse metabolomics data.In this chapter, the most commonly used chemometrics methods for data analysis ...
Data are the means ± SE of six experiments. ***P , 0.001 vs. control without insulin; £P , 0.05, ££P , 0.01, £££P , 0.001 vs. ... Changes in phosphocreatine and pyruvate/lactate levels may constitute one of the early signs of mitochondrial respiratory chain ... Neurons were preincubated with 1 μmol/l NBTI (A) or 50 μmol/l AMPCP (B). Data are the means ± SE of six experiments. *P , 0.05 ... Data analysis and statistics.. Results are the means ± SEM of the indicated number of independent experiments, run in duplicate ...
Data were statistically evaluated by one-way ANOVA (SNK) tests and Dunnetts tests, with the level of significance chosen as . ... Phosphocreatine (PCr) is an endogenous compound containing high-energy phosphate bonds. It acts as an energy reserve, and it is ... Phosphocreatine Preconditioning Attenuates Apoptosis in Ischemia-Reperfusion Injury of Rat Brain. Ling-Hua Tang, Zhong-Yuan Xia ... Phosphocreatine (PCr) is an endogenous compound containing high-energy phosphate bonds. It has been confirmed that PCr is ...
data stored in ACNUC941 zone). HOGENOM: MOUSE13_PE1286. ID MOUSE13_PE1286 STANDARD; PRT; 419 AA. AC MOUSE13_PE1286; Q6P8J7; DT ... DR GO; GO:0006603; P:phosphocreatine metabolic process; TAS:MGI. DR InterPro; IPR000749; ATP-guanido_PTrfase. DR InterPro; ... DATA ORIGIN: Translated from the HOGENOM CDS MOUSE13.PE1286. CC Mus musculus chromosome 13 NCBIM37 sequence 1..120284312 ... phosphocreatine. CC -!- SUBUNIT: Exists as an octamer composed of four CKMT2 homodimers CC (By similarity). CC -!- SUBCELLULAR ...
Surprisingly, the data also revealed a significant increase in phosphocreatine in sgk1 mutants (Figure 6). These data argue ... data not shown). These data demonstrate that neural dysfunction and degeneration are associated with sgk loss-of-function ... Together with the finding that sgk1 is less severe than sgkJS10, these data demonstrate that sgk1 is a hypomorphic, loss-of- ... The data were normalized using the mRNA expression levels of RP49. Fold change (FC) was determined using the Bio-Rad equation, ...
The expression of Cre in the BF was similar for both ChAT-Cre mouse lines (data not shown) and subsequent data were pooled. In ... and 20 sodium phosphocreatine; pH 7.3, 295 mOsm/L. Whole-cell patch-clamp recordings were obtained at room temperature using ... However, no difference in the response kinetics was observed for these data, and thus all of the data were pooled. L1 cells ... Data acquisition and offline analysis were performed using custom software written in IGOR Pro (Wavemetrics). For ...
What is Phosphocreatine kinase? Meaning of Phosphocreatine kinase medical term. What does Phosphocreatine kinase mean? ... Looking for online definition of Phosphocreatine kinase in the Medical Dictionary? Phosphocreatine kinase explanation free. ... All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for ... redirected from Phosphocreatine kinase). Also found in: Dictionary, Acronyms, Encyclopedia. creatine. [kre´ah-tin] a nonprotein ...
Data are expressed as means ± SEM. Function and 31P magnetic resonance spectroscopy data are presented as absolute values. ... Creatine, phosphocreatine, adenine nucleotides and malondialdehyde (MDA). Determination of creatine, phosphocreatine, adenine ... Kinetics of phosphocreatine (PCr) (a), adenosine triphosphate (ATP) (b) and intracellular pH (pHi) (c) in Control (male n = 10 ... Conflicting data were also obtained when responses to vasoconstricting agents were studied [30, 31]. The reason for these ...
9 depend on a sufficient energy supply and hence a sufficient phosphocreatine pool. Under normal conditions, phosphocreatine ... In conclusion, our data demonstrate that hypoxic energy failure in neonatal mice can be prevented by exogenous creatine applied ... All ATP and phosphocreatine values are given in μmol/g wet weight. Significant differences were determined by the Students t ... 1995) Phosphocreatine and ATP regulation in the hypoxic developing rat brain. Dev Brain Res 85:192-200. ...
The report generally describes phosphocreatine, sodium salt, examines its uses, production methods, patents. Phosphocreatine, ... The report also focuses on phosphocreatine, sodium salt consumers by providing data on companies that use it. ... Phosphocreatine, sodium salt prices in other regions. 7. PHOSPHOCREATINE, SODIUM SALT END-USE SECTOR 7.1. Phosphocreatine, ... Phosphocreatine, sodium salt market forecast. 6. PHOSPHOCREATINE, SODIUM SALT MARKET PRICES. 6.1. Phosphocreatine, sodium salt ...
... creatine and phosphocreatine). The spectral data were fitted in time domain with the program MRUI, based on the solving of ... Taken together, these data support the idea that IMCL can be related to insulin sensitivity independent of obesity, but also ... These data suggest that in addition to total IMCL content, study of the intramyocellular localization of fat might be of ... Data on IMCL levels are sparse but suggest, perhaps unexpectedly, that muscle triglyceride levels are similar or even higher in ...
Also, recent data have shown a high correlation of IgG-mediated antibodies between the periphery and cerebral spinal fluid in ... Also, recent data has shown a high correlation of IgG mediated antibodies between the periphery and cerebral spinal fluid in ... Emerging data show that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, ... Emerging data shows that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, ...
However, I am aware of no data that indicates that any of these forms of creatine increases creatine uptake to the muscle ... About two thirds of creatine found in the muscle is stored as phosphocreatine (PCr) while the remaining amount of creatine is ... Creatine and phosphocreatine are involved in numerous metabolic processes. Creatine synthesis deficiencies and/or abnormal ... These data indicate that creatine supplementation can directly influence muscle protein synthesis. Collectively, these studies ...
Levels of phosphocreatine and beta-nucleoside triphosphates, largely adenosine triphosphate (ATP), increased by 7% and 14%, ... The growth of the sector will be fueled by efficacy data. In recent years, efficacy data have started to accrue around some ... This results in data showing two types of errors. One, dubbed omission, arises when the participant fails to respond to a ... The positive data in middle-aged women led McGlade to assess the effect of Cognizin citicoline in another group that, for ...
Data were sampled at 50 kHz and filtered at 6 kHz (low-pass Bessel). Whole-cell membrane capacitances (15-25 pF) and series ... Na2phosphocreatine 12, EGTA 0.5, MgATP 2, LiGTP 0.5, and MgCl2 1. PH was adjusted to 7.3 with CsOH. To block Na+ currents and ... Data fitted to a single exponential decay function show an enhanced STD when ASIC-1as are blocked (mean decay time constants: ... 1e; n = 7). These data, together with the absence of acid-evoked currents in ASIC1a−/− mice suggest that ASICs in MNTB neurons ...
  • These data suggest that uMtCK is downregulated as prostate cancer progresses in correlation with a metabolic switch in ATP usage. (jcancer.org)
  • We tested the proposition that muscle cell types have different contents of phosphocreatine (PCr), ATP, and Pi by 31P NMR spectroscopy and HPLC analyses of adult rat and mouse muscles containing various volume fractions of different fiber types. (pnas.org)
  • This study illustrates the clinical feasibility of the technique, the value of a multiparametric data analysis in the definition of the pertinent variables characterizing the metabolic impairment, and the impact of localized proton MR spectroscopy of the brain in the assessment of cerebral suffering. (nih.gov)
  • Correlative analysis of magnetic resonance spectroscopy and surface electromyogram data shows that for a given surface electromyogram change, metabolic variations were always larger under hypoxaemic conditions. (portlandpress.com)
  • In the patient who underwent 31 P-MR spectroscopy, an increased phosphocreatine peak was also observed. (ajnr.org)
  • Phosphocreatine (PCr) metabolite was quantified by calculating the ratio of PCr over total phosphorus resonance from 31-Phosphorus Magnetic Resonance Spectroscopy. (clinicaltrials.gov)
  • In vivo mitochondrial function was determined by measuring phosphocreatine recovery half-time after exercise using 31 P-magnetic resonance spectroscopy. (pubmedcentralcanada.ca)
  • Recently, localised water suppressed proton magnetic resonance spectroscopy ( 1 H MRS) has opened up a new field for pathophysiological studies of cerebral ischaemia and infarction, and it can non-invasively measure various metabolites in the human brain, including N-acetylaspartate (NAA), creatine including phosphocreatine (Cr), choline containing phospholipids (Cho), and lactate (Lac). (bmj.com)
  • Spectroscopy results over the next 64 h were compared with previously established data from 12 piglets similarly subjected to transient cerebral hypoxia-ischemia, but maintained normothermic, and six sham-operated controls.The mean severity of the primary insult (judged by the time integral of depletion of [NTP]/[EPP]) was similar in the hypothermic and normothermic groups. (ucl.ac.uk)
  • A demonstration that sitagliptin improves cardiovascular fitness, (and possibly mitochondrial function) will provide important new data pertinent to the management of diabetes and pre-diabetes. (clinicaltrials.gov)
  • Specifically, pathway enrichment and correlation analyses suggested that stress induces oxidative damage by disturbing the creatine-phosphocreatine circuit and purine pathway, leading to excessive membrane breakdown. (nih.gov)
  • Methods The strategy works by simultaneously inverting the 31 P resonances of phosphocreatine (PCR) and ATP using a wide bandwidth, adiabatic inversion radiofrequency pulse followed by observing dynamic changes in intensity of the noninverted Pi signal versus the delay time between the inversion and observation pulses. (elsevier.com)
  • Gene and protein expression data from patient gliomas correlated poor patient prognoses with increased expression of ER chaperones, UPR target genes, and metabolic enzymes (glycolysis and lipogenesis). (nih.gov)
  • 4. These results suggest that hypoxaemia does not alter metabolic changes, i.e. decrease in pH and phosphocreatine during static contraction. (portlandpress.com)
  • We have developed a model that describes quantitatively the published experimental data on dependence of the rate of oxygen consumption and metabolic state of working isolated perfused rat heart on workload over its physiological range (Williamson JR, Ford G, Illingworth J, Safer B. Circ Res 38, Suppl I, I39-I51, 1976). (cellml.org)
  • To measure phosphorus metabolites in human parotid glands by 31 P-MRS using three-dimensional chemical-shift imaging (3D-CSI), and ascertain whether this method can capture changes in adenosine triphosphate (ATP) and phosphocreatine (PCr) levels due to saliva secretion. (scirp.org)
  • This was accomplished through the development of a software platform called CompPASS, which uses unbiased metrics to assign confidence measurements to interactions from parallel nonreciprocal proteomic data sets. (genes2cognition.org)
  • The WISE common core data include demographic and clinical data, symptom and psychosocial variables, coronary angiographic and ventriculographic data, brachial artery reactivity testing, resting/ambulatory electrocardiographic monitoring and a variety of blood determinations. (onlinejacc.org)
  • These data indicate that the WISE protocol is safe and feasible for identifying symptomatic women with and without significant epicardial coronary artery stenoses. (onlinejacc.org)
  • If the cognition market is to come to represent a proportion of the overall supplement market that is more indicative of the importance of brain health, ingredient suppliers must provide manufacturers with indisputable data demonstrating the efficacy of their products. (nutraingredients-usa.com)
  • Partial least square-discriminant analysis (PLS-DA) modeling of ultraperformance liquid chromatography-mass spectrometry (UPLC-MS/MS) spectral data derived from aqueous extracts of prefrontal cortex samples in the positive ion mode. (nih.gov)
  • Recent data suggest that clinical or minimal hepatic encephalopathy in cases of chronic liver disease may be the clinical manifestation of this low-grade astrocyte swelling (10, 11) . (ajnr.org)
  • Data were analysed and reported blind to patient identity and clinical course. (soton.ac.uk)
  • This review considered the quality and consistency of preclinical and clinical data. (neurology.org)
  • Based on our data an impairment of cardiac energetic state in patients with hypertrophic cardiomyopathy is indisputable. (uzh.ch)
  • The RCT on phosphocreatine found no differences in overall survival, mortality due to heart failure, echocardiographic cardiac function, and adverse events between treatment and control groups. (radcliffecardiology.com)
  • Although recent data demonstrate that rates of cardiac catheterization and diagnosis of nonfatal ischemic heart disease have doubled among women in the last decade (2) , ischemic heart disease in women is still identified less often (3,4) and at a more advanced stage (5) , and treated less aggressively (4,6) compared with that in men. (onlinejacc.org)
  • CONCLUSION The data indicate that exogenous application of creatine is effective in neuroprotection. (bmj.com)
  • The FDC-gene online data protection for photographers a guide to storing and protecting your valuable will require limited for present bacteria in both such and psychological color. (plainjanedesigners.com)
  • online data protection for photographers a guide to storing and protecting your valuable Health Publications ICON Group International, Inc. 2003 by ICON Group International, Inc. 2003 by ICON Group International, Inc. This population concludes been by world. (plainjanedesigners.com)
  • The resulting data can be easily analyzed to obtain the ATP synthesis rate using a two-site exchange model. (elsevier.com)
  • Infant follow-up included detailed measures of growth, nutritional intake, morbidities and body composition (Dual X Ray Absorptiometry, DXA) along with demographic data until 2 years corrected age. (biomedcentral.com)