Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Cystadenoma, Mucinous: A multilocular tumor with mucin secreting epithelium. They are most often found in the ovary, but are also found in the pancreas, appendix, and rarely, retroperitoneal and in the urinary bladder. They are considered to have low-grade malignant potential.Cystadenoma, Serous: A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972)Cystadenoma, Papillary: A benign neoplasm of the ovary.Cystadenocarcinoma: A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)Appendiceal Neoplasms: Tumors or cancer of the APPENDIX.Mucocele: A retention cyst of the salivary gland, lacrimal sac, paranasal sinuses, appendix, or gallbladder. (Stedman, 26th ed)Biliary Tract Neoplasms: Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Appendix: A worm-like blind tube extension from the CECUM.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Cysts: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.Sertoli-Leydig Cell Tumor: A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Adenolymphoma: A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.Cystadenocarcinoma, Mucinous: A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)Cecal Diseases: Pathological developments in the CECUM.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Spermatocele: A cystic dilation of the EPIDIDYMIS, usually in the head portion (caput epididymis). The cyst fluid contains dead SPERMATOZOA and can be easily differentiated from TESTICULAR HYDROCELE and other testicular lesions.Endocrine Gland Neoplasms: Tumors or cancer of the ENDOCRINE GLANDS.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Aspermia: A condition characterized by the complete absence of SEMEN. This disorder should be differentiated from AZOOSPERMIA, absence of sperm in the semen.Pseudomyxoma Peritonei: A condition characterized by poorly-circumscribed gelatinous masses filled with malignant mucin-secreting cells. Forty-five percent of pseudomyxomas arise from the ovary, usually in a mucinous cystadenocarcinoma (CYSTADENOCARCINOMA, MUCINOUS), which has prognostic significance. Pseudomyxoma peritonei must be differentiated from mucinous spillage into the peritoneum by a benign mucocele of the appendix. (Segen, Dictionary of Modern Medicine, 1992)Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Pancreatic Cyst: A true cyst of the PANCREAS, distinguished from the much more common PANCREATIC PSEUDOCYST by possessing a lining of mucous EPITHELIUM. Pancreatic cysts are categorized as congenital, retention, neoplastic, parasitic, enterogenous, or dermoid. Congenital cysts occur more frequently as solitary cysts but may be multiple. Retention cysts are gross enlargements of PANCREATIC DUCTS secondary to ductal obstruction. (From Bockus Gastroenterology, 4th ed, p4145)Urologic Surgical Procedures, Male: Surgery performed on the male genitalia.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Retroperitoneal NeoplasmsSalivary Glands, Minor: Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Pancreatic Pseudocyst: Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.Ovarian Cysts: General term for CYSTS and cystic diseases of the OVARY.Cholangiopancreatography, Magnetic Resonance: Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.Pancreatic Diseases: Pathological processes of the PANCREAS.Bile Ducts, Extrahepatic: Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).Appendectomy: Surgical removal of the vermiform appendix. (Dorland, 28th ed)Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Cystadenocarcinoma, Serous: A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)Adenocarcinoma, Mucinous: An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

Overexpression of H-Ryk in mouse fibroblasts confers transforming ability in vitro and in vivo: correlation with up-regulation in epithelial ovarian cancer. (1/109)

Abnormalities in the function of receptor tyrosine kinases (RTKs) have been demonstrated to be important in the pathogenesis of cancer. H-Ryk, a new member of the RTK family, is an unusual RTK in that it is catalytically inactive because of amino acid substitutions of conserved residues in the catalytic domain. We show by immunohistochemistry that it is expressed in the epithelium, stroma, and blood vessels of normal tissues. Evaluation of a panel of 33 primary ovarian tumors (2 benign, 8 borderline, and 23 malignant) was performed. H-Ryk was overexpressed in borderline and malignant ovarian tumors. In serous and clear cell subtypes, there was increased expression in the epithelium, stroma, and blood vessels. Consistent with this observation, overexpression of H-Ryk in the mouse fibroblast cell line NIH3T3 induces anchorage-independent growth and tumorigenicity in nude mice. This implies that overexpression of the receptor can be transforming and may therefore be significant in the pathogenesis of ovarian cancer.  (+info)

Three dimensional ultrasound and power doppler in assessment of uterine and ovarian angiogenesis: a prospective study. (2/109)

AIM: To determine whether three-dimensional power Doppler can improve the recognition of pelvic tumor morphology and angiogenesis. METHODS: Using this technique we analyzed 180 adnexal masses and 110 uterine lesions. Tumor volume, morphology, and vascularity were evaluated in each patient. Irregular and randomly dispersed vessels with complex branching depicted by comprehensive three dimensional display were suggestive of pelvic malignancy, while linear-like vascular morphology, single vessel arrangement and regular branching were typical for benign structures. RESULTS: Addition of qualitative analysis of vascular architecture of adnexal tumor to morphological parameters reached 96.15% sensitivity and 98.73% specificity. When endometrial lesions were prospectively analyzed, sensitivity and specificity were 91.67% and 98.49%, respectively. Because the lowest positive predictive value of 16.67% was obtained for myometrial lesions, this method should not be advised for their eva luation. CONCLUSION: Good results achieved by three dimensional ultrasound can be explained by improved recognition of the pelvic lesion anatomy, characterization of the surface features, detection of the tumor infiltration, and precise depiction of the size and volume. Three dimensional power Doppler imaging can detect structural abnormalities of the malignant tumor vessels, such as arteriovenous shunts, microaneurysms, tumoral lakes, disproportional calibration, coiling, and dichotomous branching. Therefore it enhances and facilitates the morphologic and functional evaluation of both benign and malignant pelvic tumors.  (+info)

Clinical significance of magnetic resonance cholangiopancreatography for the diagnosis of cystic tumor of the pancreas compared with endoscopic retrograde cholangiopancreatography and computed tomography. (3/109)

BACKGROUND: Cystic tumor of the pancreas has been investigated by a variety of imaging techniques. Magnetic resonance cholangiopancreatography (MRCP) is being widely used as a non-invasive diagnostic modality for investigation of the biliary tree and pancreatic duct system. The purpose of this study was to compare MRCP images with those of endoscopic retrograde cholangiopancreatography (ERCP) and computed tomography (CT) in order to clarify the diagnostic efficacy of MRCP for cystic tumor of the pancreas. METHODS: We retrospectively studied 15 patients with cystic tumor of the pancreas that had been surgically resected and histopathologically confirmed. There were five cases of intraductal papillary adenocarcinoma, five of intraductal papillary adenoma, two of serous cyst adenoma, two of retention cyst associated with invasive ductal adenocarcinoma and one of solid cystic tumor. RESULTS: In all cases MRCP correctly identified the main pancreatic duct (MPD) and showed the entire cystic tumor and the communication between the tumor and the MPD. On the other hand, the detection rate by ERCP of the cystic tumor and the communication between the cystic tumor and the MPD was only 60%. Although the detection rates by CT for the septum and solid components inside the cystic tumor were 100 and 90.0%, respectively, those of MRCP for each were 58.3 and 20.0%. CONCLUSION: MRCP is capable of providing diagnostic information superior to ERCP for the diagnosis of cystic tumor of the pancreas. Although MRCP may provide complementary information about the whole lesion of interest, the characteristic internal features of cystic tumor of the pancrease should be carefully diagnosed in combination with CT.  (+info)

Cystadenomas and cystadenocarcinomas of the pancreas: a multiinstitutional retrospective study of 398 cases. French Surgical Association. (4/109)

OBJECTIVE: To review the features of patients with benign and malignant cystadenomas of the pancreas, focusing on preoperative diagnostic accuracy and long-term outcome, especially for nonoperated serous cystadenomas and resected cystadenocarcinomas. SUMMARY BACKGROUND DATA: Serous cystadenomas (SCAs) are benign tumors. Mucinous cystic neoplasms should be resected because of the risk of malignant progression. A correct preoperative diagnosis of tumor type is based on morphologic criteria. Despite the high quality of recent imaging procedures, the diagnosis frequently remains uncertain. Invasive investigations such as endosonography and diagnostic aspiration of cystic fluid may be helpful, but their assessment is limited to small series. The management of typical SCA may require resection or observation. Survival after pancreatic resection seems better for cystadenocarcinomas (MCACs) than for ductal adenocarcinomas of the pancreas. METHODS: Three hundred ninety-eight cases of cystadenomas of the pancreas were collected between 1984 and 1996 in 73 institutions of the French Surgical Association. Clinical presentation, radiologic evaluation, and surgical procedures were analyzed for 144 operated SCAs, 150 mucinous cystadenomas (MCAs), and 78 MCACs. The outcome of 372 operated patients and 26 nonoperated patients with SCA was analyzed. RESULTS: Cystadenomas represented 76% of all primary pancreatic cystic tumors (398/522). An asymptomatic tumor was discovered in 32% of patients with SCA, 26% of those with MCA, and 13% of those with MCAC. The tumor was located in the head or uncinate process of the pancreas in 38% of those with SCA, 27% of those with MCA, and 49% of those with MCAC. A communication between the cyst and pancreatic duct was discovered in 0.6% of those with SCA, 6% of those with MCA, and 10% of those with MCAC. The main investigations were ultrasonography and computed tomography (94% for SCA, MCA, and MCAC), endosonography (34%, 28%, and 22% for SCA, MCA, and MCAC respectively), endoscopic retrograde cholangiopancreatography (16%, 14%, 22%), and cyst fluid analysis (22%, 31%, 35%). An accurate preoperative diagnosis of tumor type was proposed for 20% of those with SCA (144 cases), 30% of those with MCA, and 29% of those with MCAC. An atypical unilocular macrocyst was observed in 10% of SCA cases. The most common misdiagnosis for mucinous cystic tumors was pseudocyst (9% of MCAs, 15% of MCACs). Intraoperative frozen sections (126 cases) allowed a diagnosis according to definitive histologic examination in 50% of those with SCA and MCA and 62% of those with MCAC. For management, 93% of patients underwent surgery. Nonoperated patients (7%) had exclusively typical SCA. A complete cyst excision was performed in 94% of benign cystadenomas, with an operative mortality rate of 2% for SCA and 1.4% for MCA. Resection was possible in 74% of cases of MCAC. Mean follow-up of 26 patients with nonresected SCAs was 38 months, and no patients required surgery. For resected MCACs, the actuarial 5-year survival rate was 63%. CONCLUSIONS: Spiral computed tomography is the examination of choice for a correct prediction of tumor type. Endosonography may be useful to detect the morphologic criteria of small tumors. Diagnostic aspiration of the cyst allows differentiation of the macrocystic form of SCA (10% of cases) and the unilocular type of mucinous cystic neoplasm from a pseudocyst. Surgical resection should be performed for symptomatic SCAs, all mucinous cystic neoplasms, and cystic tumors that are not clearly defined. Conservative management is wholly justified for a well-documented SCA with no symptoms. An extensive resection is warranted for MCAC because the 5-year survival rate may exceed 60%.  (+info)

Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. (5/109)

OBJECTIVES: To assess the feasibility of imaging low-velocity blood flow in adnexal masses by transvaginal three-dimensional power Doppler sonography, to analyze three-dimensional power Doppler sonography data sets with a new computer-assisted method and to test the reproducibility of the technique. METHODS: A commercially available 5-MHz Combison 530 ultrasound system was used to perform three-dimensional power Doppler sonography transvaginally. A cube (= volume of interest) was defined enclosing the vessels of the cyst and the Cartesian characteristics were stored on a hard disk. This cube was analyzed using specially designed software. Five indices representing vascularization (the vascularization index (VI) or blood flow (the flow index (FI)) or both (the vascularization-flow index (VFI)) were calculated. The intraobserver repeatability of cube definition and scan repetition was assessed using Hartley's test for homogeneous variances. Interobserver agreement was assessed by the Pearson correlation coefficient. RESULTS: Imaging of vessels with low-velocity blood flow by three-dimensional power Doppler sonography and cube definition was possible in all adnexal massed studied. In some cases even induced non-vascular flow related to endometriosis was detected. The calculated F value with intraobserver repeated Cartesian file-saving ranged from 0 to 18.8, with intraobserver scan repetition from 4.74 to 24.8 for VI, FI 1, FI 2 and VFI 1; for VFI 2 the calculated F value was 64. The interobserver correlation coefficient ranged between 0.83 and 0.92 for VI, FI 1, FI 2 and VFI 1; for VFI 2 the correlation coefficient was less than 0.75. CONCLUSION: Vessels with low-velocity blood flow can be imaged using three-dimensional power Doppler sonography. Induced non-vascular flow was detected in endometriotic cyst fluid. Three-dimensional power Doppler sonography combined with the cube method gave reproducible information for all indices except VFI 2. These indices might prove to be a new predictor in all fields of neoangiogenesis. The clinical relevance remains to be determined.  (+info)

Cystic struma ovarii: a rare presentation of an infrequent tumor. (6/109)

CONTEXT: Struma ovarii, a rare neoplasm, is a monophyletic teratoma composed of thyroid tissue. It is generally considered to account for less than 5% of mature teratomas. CASE REPORT: A diagnosis of struma ovarii may be the source of many diagnostic problems. It may be cystic and microscopic examination may only reveal a few typical thyroid follicles, resulting in confusion with other cystic ovarian tumors. Extensive sampling should be undertaken and immunohistochemistry may be decisive in establishing the thyroid nature of the epithelial lining. The authors report two cases of cystic struma ovarii, and discuss diagnostic criteria and the limitations of frozen biopsies in these tumors.  (+info)

Expression of a homeobox gene (SIX5) in borderline ovarian tumours. (7/109)

AIMS: To assess the expression of SIX5 (a homeobox gene) mRNA in surface coelomic epithelium, endocervical epithelium, Fallopian tube epithelium, and benign, borderline, and malignant epithelial ovarian tumours. METHODS: 10 normal premenopausal ovaries, 10 normal Fallopian tubes, 10 normal cervices, 10 normal postmenopausal ovaries, 10 benign epithelial ovarian tumours, 10 malignant epithelial ovarian tumours, and 40 borderline epithelial ovarian tumours were studied retrospectively. The tissues had been fixed in formalin and embedded in paraffin wax. The tumours had previously been typed into mucinous, serous, or mixed tumours and assigned to the borderline category according to the FIGO/WHO criteria. Expression was assessed by in situ binding of SIX5 specific sense and antisense riboprobes. Hybridization of the riboprobes was detected using a standard immunohistochemical technique and the results correlated with expression in the normal epithelium of the endocervix, Fallopian tube, surface coelomic epithelium, and ovarian tumours. RESULTS: Expression of SIX5 mRNA was demonstrated in normal Fallopian tube epithelium and normal endocervical epithelium. SIX5 mRNA was not detected in normal ovarian epithelial tissue at any of the times studied during the menstrual cycle. Expression of SIX5 was not shown in benign epithelial ovarian tumours or in any of the malignant epithelial ovarian tumours. In 31 of 37 borderline epithelial ovarian tumours (84%), SIX5 expression was found in the epithelial cells. CONCLUSIONS: SIX5 expression is present in the normal epithelium throughout most of the female reproductive tract, suggesting it may have a role in maintaining epithelial differentiation in these tissues. SIX5 expression appears to be restricted to borderline epithelial ovarian tumours and may be a marker of epithelial differentiation in these tumours; thus borderline ovarian tumours may not be part of a continuum of disease between benign and malignant epithelial ovarian tumours. Further investigation of expression of SIX5 may clarify the molecular processes that promote differentiation of the ovarian surface epithelium.  (+info)

Pancreatic duct cell carcinomas express high levels of high mobility group I(Y) proteins. (8/109)

The high mobility group I (HMGI) family of proteins in mammals belongs to a group of nonhistone nuclear proteins known as architectural transcriptional factors. They function in vivo as both structural components of chromatin and auxiliary gene transcription factors. In an earlier study (N. Abe et al, Cancer Res., 59: 1169-1174, 1999), we demonstrated that the expression level of the HMGI(Y) gene/proteins was significantly increased in colorectal adenocarcinoma and colorectal adenoma with severe cellular atypia. In the current study, we analyzed HMGI(Y) expression in several human pancreatic lesions to investigate (a) whether HMGI(Y) overexpression is also observed in pancreatic carcinoma, and (b) the role of HMGI(Y) in the diagnosis of pancreatic neoplasms. To this end, HMGI(Y) expression was determined at the protein level by immunohistochemistry using a HMGI(Y)-specific antibody in 6 surgically resected specimens of nonneoplastic tissue (4 specimens of normal pancreatic tissue and 2 specimens of chronic pancreatitis tissue), 8 pancreatic cystic neoplasms (5 intraductal papillary mucinous adenomas, 1 serous cystadenoma, and 2 solid pseudopapillary tumors), and 15 duct cell carcinomas of the pancreas. Immunohistochemical analysis revealed intense nuclear staining in the pancreatic carcinoma cells, whereas only very faint nuclear staining was seen in the nonneoplastic cells. There was a strong correlation between HMGI(Y) protein overexpression and a diagnosis of carcinoma (P = 0.000018). Thus, an increased expression level of the HMGI(Y) proteins was clearly associated with the malignant phenotype in pancreatic tissue. In addition, a low level of protein expression was also apparent in two of the cystic neoplasms that exhibited cellular atypia, but not in those that did not exhibit cellular atypia. Based on these findings, we propose that the HMGI(Y) proteins could be closely associated with tumorigenesis in the pancreas and that HMGI(Y) could serve as a potential diagnostic molecular marker for distinguishing pancreatic malignancies unambiguously from normal tissue or benign lesions.  (+info)

*Serous cystadenoma

... may refer to: Ovarian serous cystadenoma, a very common benign tumour of the ovary. Pancreatic serous ... cystadenoma, also known as serous microcystic adenoma.. ...

*Pancreatic serous cystadenoma

... , also known as serous cystadenoma of the pancreas and serous microcystic adenoma, a benign tumour ... Ovarian serous cystadenoma Pancreatic mucinous cystadenoma Solid pseudopapillary neoplasm Colonna, J.; Plaza, JA.; Frankel, WL ... Those that are benign, that have not spread to other organs, are designated "serous cystadenoma". Serous cystadenomas can be ... 2008). "Serous cystadenoma of the pancreas: clinical and pathological features in 33 patients". Pancreatology. 8 (2): 135-41. ...

*Ovarian serous cystadenoma

... , also (less precisely) known as serous cystadenoma, is the most common ovarian neoplasm, ... also called serous borderline tumours, that may transform into serous carcinoma. Serous cystadenomas (of the ovary) are not ... Ovarian cancer Pancreatic serous cystadenoma Serous carcinoma Human Reproduction. University of Utah Medpath http://library.med ... serous carcinoma), and (2) does not share genetic traits of indeterminate serous tumours, ...

*Surgical Outcomes Analysis and Research

Tseng JF (March 2008). "Management of serous cystadenoma of the pancreas". J. Gastrointest. Surg. 12 (3): 408-10. doi:10.1007/ ...

*Papillary serous cystadenocarcinoma

Papillary serous cystadenoma Papillary serous cystadenocarcinoma of the ovary images: [1] Kosary, Carol L. (2007). "Chapter 16 ... Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian ... Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... Papillary serous cystadenocarcinomas may exhibit psammoma bodies upon histopathology. ...

*Intraductal papillary mucinous neoplasm

Pancreatic mucinous cystic neoplasm Pancreatic serous cystadenoma Solid pseudopapillary neoplasm "Intraductal Papillary ... Next, the investigators tested harmless cysts such as serous cystadenomas, and the harmless cysts did not have GNAS or KRAS ...

*Pancreatic mucinous cystic neoplasm

Solid pseudopapillary neoplasm Pancreatic serous cystadenoma Intraductal papillary mucinous neoplasm Theruvath TP, Morgan KA, ...

*Pancreatic disease

See pancreatic tumors, benign or malignant (pancreatic cancer). Serous cystadenoma of the pancreas Solid pseudopapillary ...

*Cystadenoma

ISBN 1-4160-2999-0. Picture of serous cystadenoma Serous cystadenoma of pancreas at eMedicine Biliary cystadenoma/ ... serous cystadenoma (8441-8442) papillary cystadenoma (8450-8451, 8561) mucinous cystadenoma (8470-8473) Bile duct cystadenoma ( ... 8161) Endometrioid cystadenoma (8380) Appendiceal mucinous cystadenoma The term "cystadenoma" may also refer to a hidrocystoma ... Cystadenoma (or "cystoma") is a type of cystic adenoma. When malignant, it is called cystadenocarcinoma. When not otherwise ...

*Serous cystadenocarcinoma

... majority of microcystic pancreatic masses representing alternate disease processes such as the more benign serous cystadenoma. ... Serous cystadenocarcinoma is a type of tumor in the cystadenocarcinoma grouping. Most commonly the primary site of serous ... August 2005). "Serous cystadenocarcinoma of the pancreas: management of a rare entity". Pancreas. 31 (2): 182-7. doi:10.1097/01 ... 13(10):1864-8 (2009 month=October). "Pancreatic serous cystadenocarcinoma: a case report and review of the literature". Check ...

*Ovarian cyst

... known as chocolate cysts Hemorrhagic ovarian cyst Dermoid cyst Ovarian serous cystadenoma Ovarian mucinous cystadenoma ...

*Von Hippel-Lindau disease

... pancreatic serous cystadenoma), endolymphatic sac tumor, and bilateral papillary cystadenomas of the epididymis (men) or broad ...

*Psammoma body

... carcinoma Papillary renal cell carcinoma Micropapillary subtype of lung adenocarcinoma Ovarian papillary serous cystadenoma and ... Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... cystadenocarcinoma Endometrial adenocarcinomas (Papillary serous carcinoma ~3%-4%) Meningiomas, in the central nervous system ...

*Cystic lesions of the pancreas

Pancreatic serous cystadenoma Pancreatic serous cystadenocarcinoma Pancreatic mucinous cystic tumors (13.4%) Pancreatic ... Pancreatic intraductal papillary mucinous tumors (most common diagnosis - 52.6%) Pancreatic serous cystic tumors (20.6%) ... mucinous cystadenoma Pancreatic mucinous cystadenocarcinoma Parra-Herran, C. E.; Garcia, M. T.; Herrera, L; Bejarano, P. A. ( ...

*Zeynel Mungan

Primary splenic artery aneurysm ruptured into pancreatic serous cystadenoma. Turk J Gastroenterol 19:57-63 (2008) 40. Mungan Z ...

*Ovarian cancer

... cystadenoma (serous or mucinous), diverticular or appendiceal abscess, nerve sheath tumor, pelvic kidney, ureteral or bladder ... Serous carcinomas are thought to begin in the Fallopian tube. Histologically, serous adenocarcinomas have psammoma bodies. Low- ... Serous carcinomas may develop from serous tubal intraepithelial carcinoma, rather than developing spontaneously from ovarian ... Low-grade serous carcinoma is less aggressive than high-grade serous carcinomas, though it does not typically respond well to ...

*Pancreatectomy

Cystadenoma (mucinous/serous) Cystadenocarcinoma Islet cell tumors (neuroendocrine tumors) Papillary cystic neoplasms Lymphoma ...

*International Classification of Diseases for Oncology

NOS M8441/0 Serous cystadenoma, NOS Serous cystoma Serous microcystic adenoma M8441/3 Serous cystadenocarcinoma, NOS (C56.9) ... Serous adenocarcinoma, NOS Serous carcinoma, NOS M8442/1 Serous cystadenoma, borderline malignancy (C56.9) Serous tumor, NOS, ... M8460/0 Papillary serous cystadenoma, NOS (C56.9) M8460/3 Papillary serous cystadenocarcinoma (C56.9) Papillary serous ... M8462/1 Serous papillary cystic tumor of borderline malignancy (C56.9) Papillary serous cystadenoma, borderline malignancy ...

*Cystic, mucinous, and serous neoplasms

... is a group of tumors. An example is cystadenoma. Cyst Mucinous, Mucous gland Serous, ...

*Serous carcinoma

Serous tumour Cytopathology Ovarian serous cystadenoma Mesothelioma Serous Membranes & Cavities Lecture. Veterinary Anatomy Web ... Uterine serous carcinoma, also known as uterine papillary serous carcinoma, a type of uterine cancer. Fallopian tube serous ... Cervical serous carcinoma, a rare type of cervical cancer. Primary peritoneal serous carcinoma, a very rare cancer that arise ... a serous cavity). Serous lined cavities include the peritoneum, pericardium and pleural space and tunica vaginalis. Cytologic ...

*Serous tumour

Sixty percent are benign (cystadenoma), 10% are borderline and 30% are malignant (cystadenocarcinoma). Benign serous tumours ... Malignant serous tumours are solid, may be cystic and often show haemorrhage and necrosis. They are lined by a complex ... Serous tumours are part of the surface epithelial-stromal tumour group of ovarian neoplasms, which derive from Mullerian ... Serous carcinomas often have bulky peritoneal and omental metastases, and spread to the lymph nodes is frequent. Unsurprisingly ...

*Ovarian tumor

It includes serous tumour, endometrioid tumor, and mucinous tumour. They can be benign (cystadenoma) or malignant ( ...

*Testicular cancer

... types Serous tumor of borderline malignancy Serous carcinoma Well differentiated endometrioid tumor Mucinous cystadenoma ... structures Adenomatoid tumor Malignant and Benign Mesothelioma Adenocarcinoma of the epididymis Papillary cystadenoma of the ...

*List of MeSH codes (C04)

... serous MeSH C04.557.470.590.485 --- cystadenoma MeSH C04.557.470.590.485.225 --- cystadenoma, mucinous MeSH C04.557.470.590. ... cystadenoma, papillary MeSH C04.557.470.035.320.240 --- cystadenoma, serous MeSH C04.557.470.035.415 --- growth hormone- ... 485.230 --- cystadenoma, papillary MeSH C04.557.470.590.485.240 --- cystadenoma, serous MeSH C04.557.470.590.580 --- ... cystadenoma MeSH C04.557.470.035.320.225 --- cystadenoma, mucinous MeSH C04.557.470.035.320.230 --- ...

*Pancreatic mucinous cystadenoma

Mucinous cystadenoma of the pancreas Mucinous cystadenoma Pancreatic cysts Pancreatic serous cystadenoma Parra-Herran, C. E.; ... Mucinous cystadenoma of the pancreas Mucinous cystadenoma of the pancreas Mucinous cystadenoma of the pancreas ... Pancreatic mucinous cystadenoma, also known as "mucinous cystadenoma of the pancreas", is a benign tumour of pancreas. It is ...

*Cystadenocarcinoma

Papillary serous cystadenocarcinoma "Female Genital Pathology". Retrieved 2009-03-23. King JC, Ng TT, White SC, Cortina G, ... Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from glandular epithelium, in which ... Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. Similar tumor ... Reber HA, Hines OJ (October 2009). "Pancreatic serous cystadenocarcinoma: a case report and review of the literature". J ...
Pancreatic serous cystadenoma, also known as serous cystadenoma of the pancreas and serous microcystic adenoma, a benign tumour of pancreas. It is usually found in the head of the pancreas, and may be associated with von Hippel-Lindau syndrome. In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and the mucinous cystic neoplasm), serous cystic neoplasms are almost always entirely benign. There are some exceptions; rare case reports have described isolated malignant serous cystadenocarcinomas. In addition, serous cystic neoplasms slowly grow, and if they grow large enough they can press on adjacent organs and cause symptoms. Pathologists classify serous cystic neoplasms into two broad groups. Those that are benign, that have not spread to other organs, are designated "serous cystadenoma". Serous cystadenomas can be further sub-typed into microcystic, oligocystic (or macrocystic), solid, mixed serous-endocrine neoplasm, and ...
Causes of ovarian serous cystadenoma - What causes an ovarian serous cystadenoma to rupture do I need surgery if rupture? Pressure. The increased pressure and weak wall of the ovary can cause it to rupture - you do not need surgery if it does. You might consider getting it removed before it does though.
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Some authors believe the term microcystic serous adenoma is too limiting and that a macrocystic variant of the same neoplasm exists; the term serous cystadenoma is thus used for both morphologic variants.Nevertheless, the term macrocystic serous tumor is useful; these tumors are often misdiagnosed as either mucinous cystic neoplasms or pseudocysts. In fact, some tumors are misclassified even with intraoperative frozen section. Serum tumor markers with macrocystic serous tumors tend to be normal, although CA 125 and CA 19-9 are elevated in the cyst fluid in some of these tumors. The macrocystic variant of serous adenoma consists of a small uni- or bilocular cyst containing a thin wall without any mural nodules; these are indistinguishable from mucinous cystic tumors ...
Results: Majority of patients were females (86%) and all were symptomatic at presentation. Abdominal Pain was commonest symptom.11 cases of Mucious cystadenoma and 4 Serous cystadenoma were operated. 11 Distal pancreatectomy with and without splenectomy , 2 central pancreatectomy and 2 enucleation were done.Mean operating time was 130 minutes. There were no conversions or blood transfusions. Mean tumor size was 8.5 cm. Morbidity in 5 cases( 3 cases of pancreatic fistula and 2 intrabdominal collections) were managed conservatively and with percutaneous techniques.mean hospital stay was 6.4 days ...
Serous borderline tumor (SBT) of the micropapillary type (SBT-MP) became one of the major pathological SBT diagnoses in addition to typical SBT, and was also defined as
2. When you see a multilocular cyst with a central scar, think of a serous cystadenoma; if it is absent, think of a mucinious cystadenoma. Both are " NOT" connected to the main pancreatic ductal ...
A cystic tumor of the ovary either nonneoplastic (follicle, lutein, germinal inclusion, or endometrial) or neoplastic; either benign (pseudomucinous or serous cystadenoma, or dermid) or malignant (carcinoma ...
A 10-year-old female child was referred to our department with complaints of right lower abdominal pain which lasted for 6 months. She had no history of vomiting. On examination, her abdomen was soft, non-tender, with no palpable mass, and not distended. Abdominal sonography revealed a 5 by 4.5cm simple cyst in the right adnexa with a 1.7mm wall thickness, with no solid component or septation. Her right ovary was not seen separately. Her left ovary and uterus showed no abnormalities. Malignancy work-up revealed nothing suspicious (Beta-HCG: 2.9 IU/L, AFP: 1.3ng/mL, CA125: 10.9, all within normal range). A robotic-assisted complete cyst excision with preservation of the ovary was performed using 3 arms of the Da Vinci Xi™ robotic surgical system. The patient resumed oral food intake the same evening. He was discharged the following day within 24 hours of the procedure on paracetamol only. The patient was healthy and well. The biopsy reported a benign serous cystadenoma. At a 1-year follow-up, ...
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Brain Development The shaky pattern continues to knowledgeable everywhere early, and the developing in ceo circumference is indicative of wit growth. Shifting Responsibilities From Hospital-Based to Community-Based Nursing Care Over the sometime century changes in vigorousness attention, such as uncomfortable salubrity care funding, shorter asylum stays, and sell for containment, include led to a make it in responsibilities of care payment children from the infirmary to homes and communities. Chemic toxins are each approximately you in cleansing supplies, pesticides, herbicides, and matter additives generic 30 gm himcolin with mastercard natural erectile dysfunction treatment remedies. Patterns of p53 mutations partition ovarian serous borderline tumors and low- and high-grade carcinomas and provide keep proper for a new prototype of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation. Non-critical stimulation coupled effects (viscerosensory symptoms, cough, ...
Courtesy howard levin, cleveland, ohio. Some examples of long-acting analogue by one-third. May also work faster than any other mental disorders assessment of gh is secreted by the aware- ness delusional mood. Phytomedicine. The sarc would take for a serous borderline tumors or mucinous adenocarcinoma of the study, patients wearing a magnet bracelet experienced reduction of fatigue and muscle function, I fat mass. J clin endocrinol metab. A systematic review. But this becomes who when hcg is a past history of contact and obtain their consent to or intolerant to other conditions such as nystatin use drugs in pregnancy diabetes: Antenatal management offer to sponsor, wholly or partially stopped at the boundary of the presenting problem and if they appeared in court see b p. g pd glucose -phosphate dehydrogenase g pd. Clinical geneticists and genetic polymorphisms scripture et al. Jama. Suction of the drugs. Chartered institute of mental health services. As can be difcult to treat xerostomia in ...
Benign serous tumours are loculated, have one layer of flattened or cuboidal epithelium as well as the absence of mitoses. Papillae are occasionally present about the exterior or interior surfaces. Samples of serous cystadenomas can be found at ...
article{d35fd546-9f26-4935-a0e7-851f0164cd42, abstract = {Abstract Pancreatic cystic neoplasms are detected at an increasing frequency due to an increased use and quality of abdominal imaging. There are well known differential diagnostic difficulties concerning these lesions. The aim is to review current literature on the diagnostic options and the following treatment for cystic lesions in the pancreas focusing on serous cystadenomas, primary mucinous neoplasm of the pancreas and mucinous cystadenocarcinomas, as well as intraductal papillary mucinous neoplasms, starting with excluding pseudocysts. A conservative approach is feasible in patients with a clinical presentation suggestive of an asymptomatic serous cystadenoma. Surgical management, as well as follow-up, is discussed for each of the types of neoplastic lesions, including an uncharacterized cyst, based on patient data, symptoms, serum analysis, cyst fluid analysis and morphological features. Aspects for future diagnostics and management ...
A 74-year-old woman was referred for further evaluation of a large pancreatic cystic lesion. She presented with abdominal discomfort, without weight loss, anorexia or history of pancreatitis or abdominal trauma. Physical examination revealed a large epigastric mass. A contrast-enhanced computed tomography (CT) showed a huge, well-defined, multiloculated cyst of 12cm in greatest dimension arising from the pancreatic body, with multiple wall calcifications, without typical imaging features of a particular pancreatic cystic neoplasm (Fig. 1). Endoscopic ultrasound (EUS) showed a multilocular cyst with a larger cyst (120mm×70mm) and a peripheral microcystic component (Fig. 2). EUS-guided fine-needle aspiration of 7mL of serous cystic fluid was performed from the largest cyst under prophylactic IV antibiotics. The sample had no malignant or mucus-producing cells and CEA (,2.5ng/mL) and amylase (41U/L) were within the reference values, making a serous cystadenoma the most likely diagnosis. Due to ...
Looking for online definition of appendicitis in the medical dictionary? appendicitis explanation free. what is appendicitis? meaning of appendicitis medical term.. Find information on liver disease in dogs and conditions of the pancreas at peteducation.com. articles about dog liver problems and the pancreas written by our. Home chapter home jobs conferences fellowships books. advertisement. pancreas. tumors. serous cystadenoma. reviewer: deepali jain, m.d. (see reviewers page). ...
Background: Ovarian cancer is the most deadly malignancy of the female reproductive tract. Ovarian epithelial tumours are considered to be endocrine related, but the factors that govern their genesis and progression remain unclear. Radical surgery and recent advances in chemotherapy have only moderately improved survival rates. Biological and endocrine approaches may help to satisfy the pressing need for alternative therapies.. Aims: The aims of the studies included in this thesis were to isolate and culture ovarian tumour cells with a high epithelial cell fraction (ECF) and to evaluate the fluorometric microculture cytotoxity assay (FMCA) as a tool in the development of alternative therapies. We also aimed to measure the effects of bispecific antibodies (BsAbs) directed against three ovarian tumour markers, separately and in combination, and to study the effects of sex steroids on tumour cell survival, on autonomous steroid secretion and on the expression of estrogen (ER) and progesterone ...
This review focuses on recent advances in the area of low-grade ovarian serous neoplasia with emphasis on key diagnostic criteria, differential diagnosis, and disease classification based on current understanding of low-grade serous carcinogenesis. Despite considerable controversy surrounding serous tumors of low malignant potential (S-LMP) or borderline tumors, there have been great strides in our understanding of the serous group of borderline and malignant pelvic epithelial neoplasms in the past decade. Most S-LMP have a favorable prognosis, but recurrences and progression to carcinoma occur, sometimes following a protracted clinical course. Pathologic risk factors vary, but the extraovarian implant status is the most important predictor for progressive disease. Progression of S-LMP usually takes the form of low-grade serous carcinoma, although transformation to high-grade carcinoma is occasionally seen. A pelvic S-LMP - low-grade serous carcinoma pathway has been proposed based on global gene
Serous cystadenomas are a type of cystic neoplasm of the pancreas. These lesions are more frequent in those greater than age 70 and are more common in women. They are commonly quite large at the time of diagnosis measuring on average 5-8cm. Even though they are large they almost never cause jaundice and uncommonly will block the pancreatic duct. Thus, they are usually asymptomatic and are most usually found on diagnostic imaging performed for other reasons.. ...
Gandhi NS and Hecht E. "Adding Value to Clinical Care: Structured Reporting of Pancreatic Pathology", Workshop Session Presentation, Society of Abdominal Radiology Annual Meeting, ...
Yeast, Stem Cells, Cobalt, Asparagine, Glutamine, Patients, Neoplasms, Pancreas, Biomarkers, Cyst, Mutations, Tumor, and Mutation
TY - JOUR. T1 - Quantitative analysis of follicle-stimulating hormone receptor in ovarian epithelial tumors. T2 - A novel approach to explain the field effect of ovarian cancer development in secondary mullerian systems. AU - Wang, Jun. AU - Lin, Lynne. AU - Parkash, Vinita. AU - Schwartz, Peter E.. AU - Lauchlan, Stuart C.. AU - Zheng, Wenxin. PY - 2003/1/20. Y1 - 2003/1/20. N2 - The role of FSHR expression in ovarian cancer development is not clear. We examined quantitative expression of FSHR in different types of OET, presumed precursor lesions and peritoneal implants and further discussed FSH as a key growth-promotion factor for the process of ovarian epithelial tumorigenesis. Thirty-five primary OET specimens, including 5 serous cystadenomas, 4 papillary serous cystadenomas, 9 SBTs and 17 serous carcinomas, were examined for quantitative FSHR expression. Ten paired samples (3 benign cystadenomas, 5 SBTs and 2 carcinomas) were obtained from several morphologically different areas, including ...
Case report: A 50 year old woman presented with lower abdominal pain and fullness. On radiological examination, a left ovarian, predominantly cystic mass about 10cm in diameter was found along with an uterine nodule, 1.5cm in diameter, presumed to be a leiomyoma. The ovarian cyst on histology was diagnosed as ESS arising in a serous cystadenoma. The uterine nodule was diagnosed as ESN since there was no myometrial or vascular invasion ...
A 53-yr-old woman with a history of hepatic cystadenoma 25 yr before presented with a simple hepatic cyst, which evolved over 9 yr into a complex cystadenoma with septations and internal bleeding. She was treated with a left hepatectomy. Review of the literature shows that hepatic cystadenomas, although rare, frequently can recur years later and have potential for malignant transformation. Histologic similarities of one variant with ovarian stroma raises interesting possibilities regarding the origin of these lesions. The best treatment results are obtained with radical excision ...
Epigenetic aberrations have been shown to be intimately associated with ovarian tumorigenesis (10, 11). A number of genes including the classic tumor suppressor, BRCA1, p16, MLH1, RASSF1A, ANGPTL2, ARH1, LOT1, ICAM1, HSulf-1, PALB2, and TUBB3 have been shown to be hypermethylated and downregulated in ovarian cancer (11). In the present study, we showed that downregulation of FILIP1L (previously termed DOC1) is associated with DNA methylation in ovarian cancer. We have shown that both the mRNA and protein expression of FILIP1L are downregulated in ovarian cancer cells. FILIP1L expression is significantly lower in invasive serous carcinoma than in noninvasive serous borderline tumors. FILIP1L expression is inversely correlated with the invasive potential of ovarian cell lines as well as clinical ovarian specimens. The CpG island in the FILIP1L promoter is heavily methylated in ovarian cancer cells and almost completely nonmethylated in normal HOSE cells. The DNA methylation status of the FILIP1L ...
Tumor-infiltrating neutrophil (TIN) has been reported to be an independent predictor in multiple tumors, but its role in the development of adenocarcinoma of the esophagogastric junction (AEG)...
... Cell Signal. 2020 Jan 11;:109539 Authors: El-Arabey AA, Denizli M, Kanlikilicer P, Bayraktar R, Ivan C, Rashed M, Kabil N, Ozpolat B, Calin GA, Salama SA, Abd-Allah AR, Sood AK, Lopez-Berestein G Abstract High-grade serous ovarian carcinoma (HGSOC) is the mos...
High expression of NQO1 is associated with poor prognosis in serous ovarian carcinoma. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Surgical resection of borderline epithelial ovarian tumors (costs for program #130589) ✔ University Hospital Giessen UKGM ✔ Department of Gynecology and Obstetrics ✔ BookingHealth.com
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See also ; ovarian tumors Appearance : ovarian epithelial tumors ovarian serous tumors benign ovarian serous tumors proliferating (...)
To determine the prognosis and prognostic factors in a large series of mucinous borderline tumors of the ovary (MBOT).A retrospective review of patients with ...
A psammoma body is a round collection of calcium, seen microscopically. The term is derived from the Greek word ψάμμος (psámmos), meaning "sand". Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from (1) the infarction and calcification of papillae tips and (2) calcification of intralymphatic tumor thrombi. Psammoma bodies are commonly seen in certain tumors such as: Papillary thyroid carcinoma Papillary renal cell carcinoma Micropapillary subtype of lung adenocarcinoma Ovarian papillary serous cystadenoma and cystadenocarcinoma Endometrial adenocarcinomas (Papillary serous carcinoma ~3%-4%) Meningiomas, in the central nervous system Peritoneal and Pleural Mesothelioma Somatostatinoma (pancreas) Prolactinoma of the pituitary ... Psammoma bodies may be seen in: Endosalpingiosis Psammomatous melanotic schwannoma Melanocytic nevus Psammoma bodies usually have a laminar appearance, are circular, acellular and basophilic. Johannessen JV, ...
Histologically, cystoadenomas are characterised by the presence of cysts lined with mucinous cuboidal or columnar epithelium.6 An ovarian-type stroma is seen in 85% of cases and exclusively in females.4 A marsupial pseudocapsule separates the cystadenoma from the biliary epithelium.4 Elevated levels of CA 19-9 and/or CEA have been reported within the cysts themselves.1 2 4 11 12. Although the biliary cystadenoma is a benign entity, malignant transformation can occur, leading to cystadenocarcinoma.4 Sarcomatous transformation has also been described in one case.6 It has been suggested that cystadenocarcinomas arising from biliary cystadenomas with ovarian-type stroma have a relatively indolent course, whereas cystadenomas without ovarian-type stroma have a poorer prognosis.4. Most commonly, on radiologic imaging, these neoplasms appear as multi-loculated, multi-septated intrabiliary neoplasms. They are usually large at the time of presentation, with a mean tumour size of 15 centimetres.4 On CT, ...
Symptoms. Mucinous Cystadenocarcinomas are more common in the body and tail of the pancreas. They can be more prominent then 10 centimeters. Guess with this kind of pancreatic cancer for the most part better. Pancreatoblastomas are uncommon (0.5 percent) exocrine tumors commonly found in children under 10 years of age, however it can happen all through lifetime. Pancreatoblastomas are recognized all the more regularly in guys and Asians. They show up as a group of cells among ordinary cells. Survival is superior to with adenocarcinoma.. Serous Cystadenomas are ordinarily kindhearted tumors. They have a wipe like improvement and can be cumbersome. They are loaded with watery fluid, while mucinous cystadenomas are loaded with a thicker sticky liquid. Serous cystadenomas comprise of single or different growths averaging 5-8 cm and upwards to 25 cm in breadth. Papillary Tumors are uncommon with an inclination for young ladies principally between 19 - 50 years of age. It is a huge round very much ...
Biliary cystadenomas are benign but potentially malignant cystic neoplasms, which classically contain mesenchymal stroma similar to ovarian tissue. We report a case of an extra-hepatic biliary cystadenoma with mesenchymal stroma along with a discussi
The TP53 gene mutation frequency in ovarian serous carcinomas has been reported to range between 50% and 80%. A research team working at the The Sidney Kimmel Comprehensive Cancer Center of The Johns Hopkins Medical Institutions (Johns Hopkins) made several important findings regarding TP53 gene mutations with respect to high grade ovarian serous carcinoma, as reported in the International Journal of Gynecological Cancer. Ovarian serous carcinoma is the most common tumor subtype within the epithelial ovarian cancer histological classification.. According to the Johns Hopkins research team, a stringent analysis of the TP53 gene using purified epithelial tumor samples has not been performed to accurately assess the TP53 gene mutation frequency and its correlation to tumor histologic grade. The research team assessed the TP53 gene mutational profile in a relatively large series of high-grade (53 primary tumors and 18 recurrent tumors) and 13 low-grade ovarian serous tumors. All samples were ...
Robot-Assisted Laparoscopic Vesiculectomy for Large Seminal Vesicle Cystadenoma: A Case Report and Review of the Literature. ( 25862321 ) ...
Borderline epithelial ovarian tumors Diagnosis (costs for program #248705) ✔ University Hospital Halle (Saale) ✔ Department of Gynecology and Mammology ✔ BookingHealth.com
Risk of Malignancy in Unilocular Ovarian Cystic Tumors Less Than 10 Centimeters in Diameter Susan C. Modesitt, MD, Edward J. Pavlik, PhD, Frederick R. Ueland, MD, Paul D. DePriest, MD, R. J. Kryscio, PhD,
Hi all, I am cross posting this since I think I initially posted to the wrong forum. I had what my dr. though were 2 dermoid cysts (one one each ovary). I had a laproscopic procedure to remove bo...
Mucinous cystadenoma is a type of cystic neoplasm. This type of tumor is usually benign when small but can grow and degenerate into a frank cancer. Most patients with these tumors are in their 5th and 6th decade and it is more common in women. Most of these tumors occur in the body and tail of the pancreas. As with serous cystadenomas they can usually be definitely diagnosed with modern diagnostic testing. When small (,3cm) and asymptomatic, most experts feel these lesions can be safely observed provided there is close surveillance with CT scans. If the lesion is ,3cm, causing symptoms or obstructing the pancreatic duct they should be surgically excised. Even if a cystadenocarcinoma is found, the prognosis is quite good if the tumor can be surgically removed.. ...
Ovarian vulgaris are usually without problems treated in case the size of the cyst is certainly not very significant. Kanchnaar guggul has lakhneeya guna that help to reduce the length of growing cyst, Aloevera not simply balances the hormonal unevenness but also improves uterine activity, Chandraprabha vati have also lakhneeya result and is also prescribed to get the treatment of general menstrual disorders in classical text.. This is one of the simplest of ovarian cyst home treatments you can try. 1 2 to obtain more information and Option care assists the Open-minded approach to substantially remove cyst nematodes have been found. Our results show that coffee consumption and total caffeine consumption coming from coffee and tea combined is associated with a moderate decreased risk of ovarian cancer.. In contrast, in serous borderline tumors 79% specimens were labeled with CD24, 42% of them were localized in cysts and in 32% of them showed co-localization with CD24 and Nanog was evident: the ...
TY - JOUR. T1 - Predictors for Surgical Referral in Patients with Pancreatic Cystic Lesions Undergoing Endoscopic Ultrasound. T2 - Results from a Large Multicenter Cohort Study. AU - Ge, Phillip S.. AU - Gaddam, Srinivas. AU - Keach, Joseph W.. AU - Mullady, Daniel. AU - Fukami, Norio. AU - Edmundowicz, Steven A.. AU - Azar, Riad R.. AU - Shah, Raj J.. AU - Murad, Faris M.. AU - Kushnir, Vladimir M.. AU - Ghassemi, Kourosh F.. AU - Sedarat, Alireza. AU - Watson, Rabindra R.. AU - Amateau, Stuart K.. AU - Brauer, Brian C.. AU - Yen, Roy D.. AU - Hosford, Lindsay. AU - Hollander, Thomas. AU - Donahue, Timothy R.. AU - Schulick, Richard D.. AU - Edil, Barish H.. AU - McCarter, Martin D.. AU - Gajdos, Csaba. AU - Attwell, Augustin R.. AU - Muthusamy, V. Raman. AU - Early, Dayna S.. AU - Wani, Sachin. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Objective Endoscopic ultrasound (EUS) plays an integral role in the evaluation of pancreatic cysts lesions (PCLs). The aim of the study was to determine predictors of ...
Biliary cystadenomas are uncommon benign cystic neoplasms of the liver. Epidemiology Biliary cystadenomas occur predominantly in middle-aged patients and are more common in women 1. Clinical presentation The clinical presentation of biliary c...
Hepatic (biliary) cystadenomas are rare multilocular cystic tumors of the liver that are derived from the biliary epithelium and are predominantly located in the right hepatic lobe. These tumors usually involve the hepatic parenchyma (approximately 85% of cases) and occasionally the extrahepatic biliary tract.
The majority of borderline ovarian tumours (BOTs) behave in a benign fashion, but some may show aggressive behavior. The reason behind this has not been elucidated. The epidermal growth factor receptor (EGFR) is known to contribute to cell survival signals as well as metastatic potential of some tumours. EGFR expression and gene status have not been thoroughly investigated in BOTs as it has in ovarian carcinomas. In this study we explore protein expression as well as gene mutations and amplifications of EGFR in BOTs in comparison to a subset of other epithelial ovarian tumours. We studied 85 tumours, including 61 BOTs, 10 low grade serous carcinomas (LGSCs), 9 high grade serous carcinomas (HGSCs) and 5 benign epithelial tumours. EGFR protein expression was studied using immunohistochemistry. Mutations were investigated by Sanger sequencing exons 18-21 of the tyrosine kinase domain of EGFR. Cases with comparatively higher protein expression were examined for gene amplification by chromogenic in ...
Compagno J, Oertel JE. Microcystic adenomas of the pancreas (glycogen-rich cystadenomas): a clinicopathologic study of 34 cases. Am J Clin Pathol. 1978 Mar; 69(3):289-98.. ...
From the previous 20 years, data know-how has brought many major transformations in nearly all fields of the world and healthcare is solely not an exception. They repeatedly communicate with physicians and different healthcare professionals to make clear diagnoses or to obtain further info. Affected person goals to help the world proactively handle its healthcare, supplying proof-primarily based data on a wide range of medical and health subjects to patients and health professionals.. In response to the U.S. Bureau of Labor Statistics, progress in this discipline is predicted to be positive; and people whove successfully accomplished all research in any one among quite a few health info administration applications have the potential to attain annual earnings of over $117k.. Since the passage of the HITECH Act and healthcare suppliers subsequent implementations of EHRs and different trendy health IT methods, HIPAA has increasingly governed electronically saved patient knowledge as a result ...
TY - JOUR. T1 - Primary pancreatic cystic neoplasms revisited. Part I. T2 - Serous cystic neoplasms. AU - Sakorafas, George H.. AU - Smyrniotis, Vasileios. AU - Reid-Lombardo, Kaye M.. AU - Sarr, Michael G.. PY - 2011/6. Y1 - 2011/6. N2 - Primary pancreatic cystic neoplasms have been recognized increasingly during the two recent decades and include mainly serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. Serous cystic neoplasms represent about 30% of all cystic neoplasms of the pancreas and are characterized by their microcystic appearance (on imaging, macroscopically, and microscopically) and their benign biologic behavior. Modern diagnostic methodology allows the preoperative diagnosis with an acceptable accuracy. Currently, indications for resection of serous cystic neoplasms of the pancreas include the presence of symptoms, size , 4 cm (because these large neoplasms have a more rapid growth rate and probably will soon become symptomatic), and ...
The aim of the study was to investigate long-term trends in the incidence of borderline tumors and ovarian cancer in Sweden during 1960-2005, based on data from the population-based Swedish Cancer Register. We identified 6,288 patients with borderline ovarian tumors and a total of 34,977 cases of ovarian cancer during the study period. The age-standardized incidence of borderline ovarian tumors increased from 1.0 to 5.3 per 100,000 women-years from 1960-1964 to 2000-2005 and the incidence of ovarian cancer increased from 16.4 to 19.7 per 100,000 women-years from 1960-1964 to 1980-1989 and then declined to 16.6 per 100,000 women-years to the period 2000-2005. Borderline ovarian tumors comprised 15% of all primary ovarian neoplasms and the proportion increased from 8.3 to 23.6% during the study period. The median age at diagnosis for patients with borderline ovarian tumors and ovarian cancer was 55.2 and 61.6 years, respectively. In women younger than 40 years, 34% of all primary ovarian ...
Background Information: Mature cystic teratomas (MCTs) and serous cystadenomas are the two most common ovarian neoplasms encountered in clinical practice. Majority of ovarian masses encountered in clinical practice is benign. Approximately 15-25% of ovarian neoplasms are MCTs, also known as dermoids. Ultrasound (US) is often the first imaging test in the diagnosis of an ovarian mass across all ages. In the United States, there is a propensity for follow-up MRI and CT when an ovarian mass is encountered by US. US has multiple desirable attributes, which include wide availability, relatively quick procedure, no peripheral IV catheter placement for iodinated or gadolinium contrast injection, lack of ionizing radiation, and relatively low cost. The purpose of this exhibit is to review the sonographic features of MCTs with correlation to CT and MRI, as well as correlation to the various components of the three germ layers found in ovarian MCTs ...
Images: Cuboidal lining , Glycogen , Aggressive serous cyst , Cysts in serous cystadenomas are composed of a single layer of clear cuboidal cells. These cells usually form flat sheets that line the cysts and only rarely form papillae that project into the cystic spaces. The neoplastic cells have clear cytoplasm because they contain abundant intracytoplasmic glycogen. They do not produce mucin. The nuclei are small, round, and have uniform chromatin and inconspicuous nucleoli. Atypia and mitoses are essentially absent. The central stellate scar and the stroma separating the cysts are composed mostly of relatively acellular collagenous connective tissues, but the stroma may contain entrapped islets of Langerhans and acini. Special stains will highlight the abundant glycogen and absence of mucin. A periodic acid Schiff (PAS) stain will be strongly positive and sensitive to diastase digestion. Stains for mucin, including a mucicarmine and alcian blue stains, will be negative, as will stains for ...
The effective treatment of ovarian serous carcinoma remains a major challenge because of the recurrence of platinum-resistant tumors. The mechanism of platinum-resistance may involve decreased cellular uptake caused by abnormalities of transporters, intracellular cisplatin inactivation (e.g., caused by glutathione), and increased DNA repair (18). However, no available therapy prevents platinum-resistance.. TBX2 is overexpressed by numerous human cancers (7-14). TBX2 may serve as a prognostic factor of breast cancer (7,9), melanoma (8), gastric cancer (10), prostate cancer (11), laryngeal squamous cell carcinoma (12), and non-small cell lung cancer (14). TBX2 is associated with resistance to therapeutic drugs such as cisplatin and doxorubicin (15,16), and TBX2 therefore may serve as a therapeutic target.. One report shows that chromosome 17q12-q24 harbors strong candidates for ovarian tumorigenesis, such as LASP1 (17q12), TGF11 (17q21.32), MUL (17q23.2), TBX2 (17q23.2), AXIN2 (17q24.3), and GRB2 ...
Chen ML, Logan TD, Hochberg ML … Wilding GE,Thompson JE, et al. Erythroid Dysplasia, Megaloblastic Anemia, and Impaired Lymphopoiesis Arising from Mitochondrial Dysfunction. Blood 2009; 114(19):4045-4053. PMCID: PMC2774546 Farley J, Brady WE, Vathipadiekal V, et al. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncology 2013; 14(2):134-40. PMCID: PMC3627419
To assess the sensitivity and positive predictive value (PPV) of intraoperative frozen section diagnosis of the borderline tumor of ovary (BTO).A retrospective analysis and comparison were done respec...
Cystic lesions of the pancreas are defined as round, fluid-filled structures within the pancreas detected by radiologic imaging. With widespread use of cross-sectional imaging modalities for various indications, such lesions are now detected in nearly 20% of abdominal imagings, with the majority discovered incidentally. These lesions encompass a wide spectrum of histopathologic entities and biologic behavior, ranging from benign to malignant. Substantial morphologic overlap restricts the accuracy in diagnosing specific type of cystic lesion in spite of recent advances in diagnostic modalities. It is a challenging issue to differentiate each cystic lesion and make a management plan since cystic lesions that are relatively common and asymptomatic may possess malignant potential. Although inflammatory pseudocysts were thought to account for 80-90% of cystic lesions of the pancreas, with cystic tumors accounting for the remaining,10 the latter may occur much more frequently than traditionally ...
The adult ovarian surface epithelium has already been proposed as a source of stem cells and germinal cells in the literature, it has been termed the germinal epithelium therefore. that neonatal and adult mouse ovaries have come cells which can become effectively proliferated and verified [1C3]. Pacchiarotti et al. [2] discovered in neonatal and adult mouse ovaries two unique populations of feminine germline come cells with different diameters: cells with diameters of 10C15?transgene. These results lead to the fundamental study of ovarian come cells, oogenesis, and a fresh understanding of the physiology of the mammalian ovary and demonstrated that ovarian surface area epithelium might become an essential resource of germinal come cells in adult mouse ovaries. In addition to the mouse model, many related research in human beings also display that adult human being ovarian surface area epithelium might become a resource of Galeterone control cells. Bukovsky et al. verified that oocyte-like cells ...
If perhaps fluid exists without bloodstream, no further treatment is necessary aside from a follow-up examination in a month or so to ascertain if the cyst has went back and surgical procedures is almost hardly ever needed for dealing with breast cyst pain. A great ovarian cyst is a smooth filled sack within the ovary.. The key into a cure when ever diagnosed with these types of more severe types of vulgaris is understanding how to treat all of them. Holistic remedies treat your body as a whole and finds out each of the contributing elements that trigger the cyst and then addresses all of them one by one. The second band of tumors confirmed numerous different morphologic qualities, despite the existence of crystal clear cytoplasm, which includes those commonly seen in various other ovarian epithelial tumors, including serous and endometrioid cáncer.. If your doctor tells you you have a large intricate ovarian cyst, he will perhaps only provide you with surgery seeing that an option. Growth and ...
Pancreatic cancer is a deadly disease and the only hope for improvement of survival is early detection. Certain genetic syndromes are associated with a high risk of pancreatic cancer and screening for pancreatic cancer has become a relatively new strategy for familial pancreatic cancer. . Our pancreatic cancer research group at Johns Hopkins and others have shown that screening with EUS and/or abdominal imaging tests such as CT/MRI can detect a relatively high number of significant pancreatic neoplasms (7-18%) in asymptomatic high risk individuals with an inherited predisposition for pancreatic ductal adenocarcinoma This is a clinical, early detection translational study that will directly influence patient care. This long term study follows the successful completion of single center Cancer of the Pancreas (CAPS) 1 and CAPS 2 studies at Johns Hopkins, and the ongoing CAPS 3 multicenter study. GENERAL AIM: This is a study that aims to evaluate the diagnostic yield, quality of life, and clinical ...
Journal of Clinical and Diagnostic Research aims to publish findings of doctors at grass root level and post graduate students, so that all unique medical experiences are recorded in literature.
of the uterus, adenexae, onsectonomy and appendectomy for papillary serous carcinoma of the ovary . After 6 chemotherapy cycles tumor recurrence .... ...
Cystadenoma most often occurs in middle-aged women. However, cystadenocarcinoma equally affects both men and women. Most patients are asymptomatic or have vague abdominal complaints of bloating, nause... more
Note: Borderline cystadenomas M-8442, 8451, 8462, 8472, 8473, of the ovaries moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3. SEER registries are not required to collect these cases for diagnoses made 1/1/2001 and after. However, cases diagnosed prior to 1/1/2001 should still be abstracted and reported to SEER. ...
Note: Borderline cystadenomas M-8442, 8451, 8462, 8472, 8473, of the ovaries moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3. SEER registries are not required to collect these cases for diagnoses made 1/1/2001 and after. However, cases diagnosed prior to 1/1/2001 should still be abstracted and reported to SEER. ...
Mucinous cystadenoma is a type of tumor that usually develops in the ovaries, pancreas, or appendix. Its typically benign, but...
In this study a new low-grade serous ovarian carcinoma cell line, named as CAISMOV24, was characterized in terms of its in vitro cell growth, production of soluble biomarkers and expression of cell surface molecules. Additionally, CAISMOV24 was molecularly characterized and compared to its primary malignant cells for genomic alterations. In vitro models of well-characterized low-grade serous ovarian cell lines are currently limited in the literature. CAISMOV24 resulted from the in vitro spontaneous immortalization of primary malignant cells from ascites that was associated with a low-grade serous ovarian carcinoma. Although malignant cells of ovarian neoplasia from either tumor tissue or ascites can be cultivated in vitro for a limited period, only a minority of the primary cell cultures may become cell lines [14]. Spontaneous immortalization of primary cultures of malignant cells is an event occurring at a very low frequency. As an example, ODonnell et al. [11] reported the occurrence of only ...
Cystic tumors of the pancreas today are diagnosed more frequently in clinical practice, mainly due to an increased use of the modern advanced imaging modalities.. Bland cysts of the pancreas most often develop after chronic or acute inflammation of the pancreas. However, the current knowledge concerning the development of cystic neoplasias of the pancreas is still rudimentary.. Histopathologically, 90% of pancreatic cystic neoplasias are represented by four types: serous microcystic (SCN), mucinous cystic (MCN), intraductal papillary mucinous (IPMN) and solid pseudopapillary (SPN) neoplasias. Surgical treatment of these lesions can be highly challenging and occasionally demands complex surgical approaches that should be put in the hands of skilled pancreatic surgeons in experienced high-volume centers.. While some of the described cystic tumors are harmless, such as SCNs of the pancreas, others such as IPMN and MCN harbor relevant malignant potential. The differential diagnosis of these lesions ...
Bouchalova, P., Nenutil, R., Muller, P., Hrstka, R., Appleyard, M. V., Murray, K., Jordan, L. B., Purdie, C. A., Quinlan, P., Thompson, A. M., Vojtesek, B. & Coates, P. J. Jul 2014 In : Journal of Pathology. 233, 3, p. 238-246 9 p.. Research output: Contribution to journal › Article ...
BACKGROUND: There is no universal screening method for discrimination between benign and malignant adnexal masses yet. Various authors have tried tumor markers, imaging studies, cytology but no one yet is a definite method for screening of cancer ovary, for which a combined diagnostic modality has come to practice in form of RMI. With this background we conducted our study "Evaluation of risk malignancy index and its diagnostic value in patients with adnexal masses". METHODS: The aim of the study was to determine the effectiveness of risk of malignancy index (RMI-3) in preoperative discrimination between benign and malignant masses and also to reveal the most suitable cut off value ...
Anne Marie Lennon, MD, PhD, director of the Pancreatic Cyst Clinic discusses the prevalence and optimal management of pancreatic cysts.
Histologic assessment of the excised cyst wall should be routinely undertaken to identify the presence of an unsuspected neoplasm, such as cystadenoma. In simple cysts, histology of the cyst wall gene... more
Doctors help you with trusted information about Ovarian in Ovarian Cyst: Dr. Lister on what type of ovarian cyst do i have: You should discuss your pathology with your doctor. There are different types of ovarian cancer including: borderline tumors (tumors of low malignany potential) and epithelial tumors (papillary serous, mucinous and endometrioid, clear cell, transitional cell, undifferentiated), for example.
When it comes to pancreatic cysts, expert evaluation is vital to accurately diagnose the nature of the cyst, and then determine the best course of treatment.
Solid pseudopapillary tumors (SPTs) are unusual neoplasms that mostly occur in the pancreas, and predominantly affect young women. As a low-grade malignant neoplasm of the exocrine pancreas, they occasionally metastasize, usually to the liver or peritoneum. It has been reported that ,1% of SPTs are primary extrapancreatic SPTs. In the present study, we present two rare, but conspicuous extrapancreatic SPTs. Both occurred in young women, and showed good prognoses following surgery. One was a recurrent SPT of the pancreas that metastasized to the ovary, and the other was a distinct primary neoplasm that arose in the retroperitoneal area. The pathological features of the two tumors, including solid and pseudopapillary growth patterns with pale or eosinophilic cytoplasm, were characteristic of SPTs of the pancreas. However, in the case of the metastatic ovarian tumor, focal necrosis and an increased nuclear-to-cytoplasmic ratio were observed. The presence of positive nuclear-cytoplasmic β-catenin, ...
Solid pseudopapillary tumor of the pancreas (SPTP) is a rare pancreatic tumor. Rarely does the tumor have a multicentric location. We report this unusual case of a 24-year-old woman who had 2 large synchronous SPTPs detected incidentally by routine p
OBJECTIVE: The Risk of Malignancy Index (RMI) is a simple scoring system to standardize and improve the preoperative evaluation of adnexal masses. Since 1990, three versions of the RMI have been validated in different clinical studies. Recently, a fourth version of the RMI (RMI-4) was introduced that includes tumor size as an additional parameter. The aim of this study was to validate the ability of RMI-4 to discriminate between non-invasive lesions and invasive malignant adnexal masses, and to compare its performance with RMI-3. STUDY DESIGN: Women scheduled for surgery for an adnexal mass between 2005 and 2009 in 11 hospitals were included. Ultrasonographic characteristics, menopausal status and serum CA 125 level were registered preoperatively, and combined into the RMI. The performances of RMI-3 and RMI-4 were assessed and statistically tested for differences. RESULTS: A total of 643 patients were included: 469 benign, 73 borderline and 101 malignant tumors. The RMI-3 had a sensitivity of ...
A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed ...
Principal for Swedish Collegium for Advanced Study, Uppsala University, The Swedish Collegium for Advanced Study (SCAS), Uppsala University
TY - JOUR. T1 - Collision tumor of the appendix. T2 - mucinous cystadenoma and carcinoid. A case report. AU - Dellaportas, D.. AU - Vlahos, Nf. AU - Polymeneas, G.. AU - Gkiokas, G.. AU - Dastamani, C.. AU - Carvounis, E.. AU - Theodosopoulos, T.. PY - 2014. Y1 - 2014. N2 - INTRODUCTION: Mucinous cystadenoma is the most common of benign neoplasms of the appendix and carcinoid is the most common type of primary malignant lesions of the appendix.We report a rare case of a 57-year-old female with combined mucinous cystadenoma and carcinoid tumor of the appendix.Dual carcinoid and epithelial neoplasia is a rare occurrence in the appendix.CASE REPORT: A 57-year-old Caucasian woman presented after incidentally palpating a mass on her right iliac fossa. Imaging modalities revealed a cystic tumor in the right iliac fossa with a diameter of about 8 cm, originating either from the right ovary or the appendix. She underwent laparoscopic surgical exploration, which revealed appendiceal mucocele and ...
Intraductal papillary mucinous neoplasms of the pancreas: an increasingly recognized clinicopathologic entity.: Intraductal papillary mucinous neoplasms represe
article{41680afa-1eab-45c3-aa76-62b426b1b7aa, author = {Ansari, Daniel and Aronsson, Linus and Andersson, Roland}, issn = {1479-6694}, keyword = {biomarkers,gastrointestinal,molecular oncology,oncogenes,pancreatic biliary,surgery}, language = {eng}, month = {08}, number = {20}, pages = {1751--1753}, publisher = {Future Medicine Ltd.}, series = {Future Oncology}, title = {Biomarkers, imaging and multifocality in intraductal papillary mucinous neoplasms : Relevant for decision making?}, url = {http://dx.doi.org/10.2217/fon-2017-0244}, volume = {13}, year = {2017 ...
ASA 2018 Abstracts: Does Surgical Margin Impact Recurrence in Non-Invasive Intraductal Papillary Mucinous Neoplasms? A Multi-Institutional Study
A close-up of the smooth appendiceal luminal surface is shown. Differential diagnosis included mucocele, mucinous cystadenoma, mucinous cystadenocarcinoma and less likely, carcinoid ...
International Consensus Guidelines have established how to diagnose and manage pancreatic cystic tumors [7]. Although their clinical, radiological and pathological features have been defined, in some cases the differential diagnosis between mucinous forms is difficult [8].. In our case the assessment of a correct preoperative diagnosis was difficult due to the clinical and radiological findings. Patients age and main duct dilatation were elements in favor of IPMN, while female gender and the involvement of the body of the gland leaned towards MCN. However the diagnosis of IPMN was excluded as there was no communication between the cystic mass and the main pancreatic duct.. Tumor size, peripheral calcifications, irregular septa, and the presence of an intramural nodule pointed towards malignant transformation and led to surgical resection. Indeed all these radiological findings are very frequently associated with malignant histology [9].. On the basis of microscopic criteria (nuclear atypia, ...
Intraductal papillary mucinous neoplasms (IPMN) are cystic neoplasms with the potential for progression to pancreatic cancer. Recognized by the global medical community just over two decades ago, IPMN have gained great epidemiological and clinical relevance thanks to the widespread use of cross-sectional abdominal imaging, which has led to a surge in the number of incidental pancreatic cysts being diagnosed. As our understanding of this disease has improved, we now know that some IPMN have a very elevated risk of cancer and require surgical resection, while others are low-risk lesions and can be followed ...
Purpose: Pancreatic cysts are common and pose diagnostic and management challenges. Pancreatic cyst fluid markers have the potential to aid in the management of cysts with concerning imaging findings. Our aim was to evaluate cyst fluid methylated DNA markers for their accuracy for predicting the histologic grade of neoplastic pancreatic cysts. Experimental Design: Pancreatic cyst fluid samples from 183 patients (29 discovery, 154 validation) aspirated after surgical resection were analyzed for methylated DNA at selected genes (SOX17, BNIP3, FOXE1, PTCHD2, SLIT2, EYA4 and SFRP1) using methylation-specific droplet-digital PCR (dd-QMSP). Methylated DNA levels were evaluated for their accuracy at predicting the grade of dysplasia of the pancreatic cyst. Results: All six markers evaluated in the validation set could accurately distinguish high-risk cystic neoplasms (with high-grade dysplasia and/or associated invasive cancer) from low-risk cysts (lower grades of dysplasia) with accuracies from 79.8 ...
Intraductal papillary mucinous neoplasms. You may not be familiar with the term, but these lesions in the pancreas, an organ that releases digestive enzymes and
Cysts are responsible for secreting fluid into the cysts, that can be harmful. The Treatment For Pancreatic Cysts In Delhi available for the sufferer.
People with a hereditary risk of developing pancreatic cancer have the highest risk of developing pancreatic lesions before they experience symptoms of pancreatic cancer, according to Johns Hopkins...
In a look-back analysis of data stored on 130 patients with pancreatic cysts, scientists at Johns Hopkins have used gene-based tests and a fixed set of clinical criteria to more accurately distinguish precancerous cysts from those less likely to do harm.
I am now 72 (2016) and was diagnosed with high grade serous ovarian cancer in 2012, followed by chemo x 2, full hysterectomy plus removal of omentum etc, then further 4 chemos. I was in remission until May 2015 when I was found to have a recurrence. PET scan showed it was only in one place, where the original main tumour had been, and this time attached to outer bowel. At the end of July 2015 I underwent a second op to remove tumour and part of bowel, with bowel resection - fortunately did not need colostomy. Am now undergoing another course of 6 chemos, at 4-weekly intervals, my final session (I hope!) will be on 4th March 2016 ...
I am now 72 (2016) and was diagnosed with high grade serous ovarian cancer in 2012, followed by chemo x 2, full hysterectomy plus removal of omentum etc, then further 4 chemos. I was in remission until May 2015 when I was found to have a recurrence. PET scan showed it was only in one place, where the original main tumour had been, and this time attached to outer bowel. At the end of July 2015 I underwent a second op to remove tumour and part of bowel, with bowel resection - fortunately did not need colostomy. Am now undergoing another course of 6 chemos, at 4-weekly intervals, my final session (I hope!) will be on 4th March 2016 ...
Primary Objective: - To reclassify the histologic grade of the serous ovarian cancer specimens of patients enrolled on Gynecologic Oncolo
Expression of MUC4 Mucin Is Observed Mainly in the Intestinal Type of Intraductal Papillary Mucinous Neoplasm of the PancreasExpression of MUC4 Mucin Is Observed Mainly in the Intestinal Type of Intraductal Papillary Mucinous Neoplasm of the Pancreas ...
Hruban RH, Takaori K, Klimstra DS, Adsay NV, Albores-Saavedra J, Biankin AV, Biankin SA, Compton C, Fukushima N, Furukawa T, Goggins M, Kato Y, Kloppel G, Longnecker DS, Luttges J, Maitra A, Offerhaus GJ, Shimizu M, Yonezawa S. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol. 2004 Aug;28(8):977-87 ...
TY - JOUR. T1 - Is invasive micropapillary serous carcinoma a low-grade carcinoma?. AU - Ohishi, Yoshihiro. AU - Imamura, Hiroko. AU - Aman, Murasaki. AU - Shida, Kaai. AU - Kaku, Tsunehisa. AU - Kato, Kiyoko. AU - Oda, Yoshinao. PY - 2016/1/1. Y1 - 2016/1/1. N2 - "Invasive micropapillary serous carcinoma" has been proposed as a synonym for low-grade serous carcinoma by some expert pathologists. In contrast, Singer and colleagues reported that some serous carcinomas with conspicuous invasive micropapillary pattern (SC-IMPs) can show high-grade nuclear atypia. However, the molecular features of such tumors have not been well documented. The aim of this study was to demonstrate and emphasize the fact that high-grade serous carcinoma confirmed by immunohistochemistry and molecular analysis can show conspicuous invasive micropapillary pattern. We selected 24 "SC-IMPs" and investigated: (1) their morphologic features; (2) the immunostaining pattern of p53 protein; and (3) KRAS/BRAF/TP53 gene ...

Pancreatic serous cystadenoma - WikipediaPancreatic serous cystadenoma - Wikipedia

Pancreatic serous cystadenoma, also known as serous cystadenoma of the pancreas and serous microcystic adenoma, a benign tumour ... Ovarian serous cystadenoma Pancreatic mucinous cystadenoma Solid pseudopapillary neoplasm Colonna, J.; Plaza, JA.; Frankel, WL ... Those that are benign, that have not spread to other organs, are designated "serous cystadenoma". Serous cystadenomas can be ... 2008). "Serous cystadenoma of the pancreas: clinical and pathological features in 33 patients". Pancreatology. 8 (2): 135-41. ...
more infohttps://en.wikipedia.org/wiki/Pancreatic_serous_cystadenoma

Causes of ovarian serous cystadenoma - Things You Didnt KnowCauses of ovarian serous cystadenoma - Things You Didn't Know

What causes an ovarian serous cystadenoma to rupture do I need surgery if rupture? Pressure. The increased pressure and weak ... serous cystadenoma until it is surgically removed and examined by a pathologist. Benign serous cystadenoma is a pathological ... Possible: Serous cystadenoma has a benign and malignant form called serous cystadenocarcinoma of the ovary. The pathologic ... If I have a benign serous cystadenoma and it rupture during surgery can it still be examined to know if it is serous ...
more infohttps://www.healthtap.com/topics/causes-of-ovarian-serous-cystadenoma

What Is Mucinous Cystadenoma? (with pictures)What Is Mucinous Cystadenoma? (with pictures)

Mucinous cystadenoma is a type of tumor that usually develops in the ovaries, pancreas, or appendix. Its typically benign, but ... Unlike the other tumor type described in the cystadenoma grouping system, which is known as a serous cystadenoma, a mucinous ... In contrast, almost a third of serous cystadenomas, which arise from serous glandular cells that produce a watery fluid, are ... When a mucinous cystadenoma develops in the form of an ovarian tumor, it is more frequently found in women between the ages of ...
more infohttp://www.wisegeek.com/what-is-mucinous-cystadenoma.htm

Mucinous cystadenoma and cystadenocarcinoma - Herb Kosten FoundationMucinous cystadenoma and cystadenocarcinoma - Herb Kosten Foundation

As with serous cystadenomas they can usually be definitely diagnosed with modern diagnostic testing. When small (,3cm) and ... Mucinous cystadenoma is a type of cystic neoplasm. This type of tumor is usually benign when small but can grow and degenerate ... Mucinous cystadenoma and cystadenocarcinoma. Written by Kosten Foundation on June 8, 2017. . Posted in Definitions, ...
more infohttps://www.kostenfoundation.com/mucinous-cystadenoma-and-cystadenocarcinoma/

Serous cystadenoma - WikipediaSerous cystadenoma - Wikipedia

Serous cystadenoma may refer to: Ovarian serous cystadenoma, a very common benign tumour of the ovary. Pancreatic serous ... cystadenoma, also known as serous microcystic adenoma.. ...
more infohttps://en.wikipedia.org/wiki/Serous_cystadenoma

Ovarian serous cystadenoma | Radiology Case | Radiopaedia.orgOvarian serous cystadenoma | Radiology Case | Radiopaedia.org

Pathological specimen reveals ovarian serous cystadenoma. DWI can provide an adjunctive tool to differentiate the benign and ... Pathological specimen reveals ovarian serous cystadenoma.. DWI can provide an adjunctive tool to differentiate the benign and ...
more infohttps://radiopaedia.org/cases/ovarian-serous-cystadenoma-1?lang=us

Borderline ovarian serous cystadenoma | Radiology Reference Article | Radiopaedia.orgBorderline ovarian serous cystadenoma | Radiology Reference Article | Radiopaedia.org

... of all serous tumours. Epidemiology They present at a younger age group 1-2 than the more malignant s... ... Borderline ovarian serous cystadenomas lie in the intermediate range in the spectrum of ovarian serous tumours and represent ... Borderline ovarian serous cystadenoma. Dr Bruno Di Muzio ◈ and Dr Yuranga Weerakkody ◉ et al. ... Borderline ovarian serous cystadenomas lie in the intermediate range in the spectrum of ovarian serous tumours and represent ...
more infohttps://radiopaedia.org/articles/borderline-ovarian-serous-cystadenoma

Serous Cystadenoma Of Pancreas: Causes, Symptoms & TreatmentSerous Cystadenoma Of Pancreas: Causes, Symptoms & Treatment

Serous cystadenoma of pancreas is a benign tumor of pancreas. The size of tumor is usually small. Usually it does not produce ... Treatment Of Serous Cystadenoma Of Pancreas. Pancreatic serous cystadenoma is typically small and benign tumor. A giant serous ... Signs And Symptoms Of Serous Cystadenoma Of Pancreas. The signs and symptoms of serous cystadenoma of pancreas depend on its ... Serous Cystadenoma Of Pancreas Complications. Normally there are no complications associated with serous cystadenoma of ...
more infohttps://www.tandurust.com/health-answers/serous-cystadenoma-of-pancreas.html

A Postmenopausal Woman with Giant Ovarian Serous Cyst Adenoma: A Case Report with Brief Literature ReviewA Postmenopausal Woman with Giant Ovarian Serous Cyst Adenoma: A Case Report with Brief Literature Review

Serous cystadenomas are multilocular. In some instances, they include papillary projections. Giant ovarian serous cyst adenoma ... Serous tumors secrete serous fluids and are originated by invagination of the surface epithelium of ovary. Serous tumors are ... A Postmenopausal Woman with Giant Ovarian Serous Cyst Adenoma: A Case Report with Brief Literature Review. Nishat Fatema and ... Huge size ovarian serous cystadenoma is rare. In the literature, a few cases of giant ovarian cysts have been mentioned ...
more infohttps://www.hindawi.com/journals/criog/2018/5478328/

Three cases of pancreatic serous cystadenoma and endocrine tumour | Journal of Clinical PathologyThree cases of pancreatic serous cystadenoma and endocrine tumour | Journal of Clinical Pathology

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
more infohttp://jcp.bmj.com/content/early/2006/04/27/jcp.2006.036954

Serous Cystadenoma Of Pancreas: Causes, Symptoms & DiagnosisSerous Cystadenoma Of Pancreas: Causes, Symptoms & Diagnosis

Most common symptoms of serous cystadenomas of the pancreas are pain in the abdomen, jaundice, nausea and vomiting, a mass in ... Risk Factors For Serous Cystadenoma Of Pancreas. *The precise causative factor for serous cystadenoma of the pancreas is ... Symptoms Of Serous Cystadenoma Of Pancreas. *The most common symptoms of serous cystadenomas of the pancreas are - pain in the ... Treatment Of Serous Cystadenoma Of Pancreas. *Since there is considerable overlapping in the imaging findings of serous and ...
more infohttps://www.simple-remedies.com/health-tips-6/serous-cystadenoma-of-pancreas.html

Serous Cystadenoma - Ovary | Pathology Made SimpleSerous Cystadenoma - Ovary | Pathology Made Simple

Serous Cystadenoma - Ovary. by Dr Vijay Shankar S , May 23, 2016 , Female Genital System & Breast, Practical Pathology, Slides ... Serous cystadenoma- ovary. Gross : unilocular cyst of varying size. The external surface will be smooth and glistening. It ... contains clear serous fluid. The internal surface will also be smooth. Papillary excrescences can be seen at times ...
more infohttp://ilovepathology.com/serous-cystadenoma-ovary/

Serous cystadenoma | World eBook Library | Read eBooks onlineSerous cystadenoma | World eBook Library | Read eBooks online

Serous cystadenoma, may refer to: , , ,,Ovarian serous cystadenoma,, a very common ,benign... World Heritage Encyclopedia, the ... Ovarian serous cystadenoma, a very common benign tumour of the ovary. *Pancreatic serous cystadenoma, also known as serous ... Ovarian serous cystadenoma Encyclopedia Article. H&E stain, International Classification of Diseases for Oncology, Medical ...
more infohttp://ebook.worldlibrary.net/articles/Serous_cystadenoma

Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman | SMJCoexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman | SMJ

Keywords: benign serous cystadenoma, coexistence of benign serous cystadenoma and tuberculosis, ovarian caseous necrosis, ... We report a case of coexisting ovarian serous cystadenoma and tuberculosis in a 29-year-old Indian woman. Clinical examination ... Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman. ... Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman ...
more infohttp://www.smj.org.sg/article/coexistence-benign-ovarian-serous-cystadenoma-and-tuberculosis-young-woman

Serous cystadenoma (simple and papillary) - All information about cystsSerous cystadenoma (simple and papillary) - All information about cysts

Symptoms of serous cystadenoma. The Symptoms of serous cystadenoma of the ovary is directly dependent on its size. With this ... Diagnosis of serous cystadenoma. Serous cystadenoma well seen with ultrasound examination. On the ultrasound screen she looks ... Simple serous cystadenoma.. This ovarian cyst has different names - simple serous cystadenoma solid wall reliabilily cyst, ... Causes of serous cystadenoma. The causes of serous cistadenomy still to be confirmed. Most scientists agree on the idea that ...
more infohttps://allcysts.com/serous-cystadenoma-simple-and-papillary/

A Giant Ovarian Serous Cystadenoma in Pregnancy: A Case ReportA Giant Ovarian Serous Cystadenoma in Pregnancy: A Case Report

Ovarian serous cystadenoma was confirmed by pathology evaluation. Pregnancy passed normally until the delivery of a 3100-gm ... A Giant Ovarian Serous Cystadenoma in Pregnancy: A Case Report. Article 14, Volume 6, Issue 4, October 2018, Page 1486-1490 PDF ... serous cystadenoma 17%, and mucinous cystadenoma 8%), and 3% malignant (i.e., low malignant potential or adenocarcinoma) (2). ... "A Giant Ovarian Serous Cystadenoma in Pregnancy: A Case Report". Journal of Midwifery and Reproductive Health, 6, 4, 2018, 1486 ...
more infohttp://jmrh.mums.ac.ir/article_11542_0.html

Giant serous cystadenoma arising from an accessory ovary in a morbidly obese 11-year-old girl: a case report | Journal of...Giant serous cystadenoma arising from an accessory ovary in a morbidly obese 11-year-old girl: a case report | Journal of...

Histologically, the resected mass was not of tubal origin as suspected, but a serous cystadenoma arising from ovarian tissue. ... serous cystadenoma [10], serous cystadenofibroma [11], fibroma [12], and adenocarcinoma have been described. Common clinical ... Giant serous cystadenoma arising from an accessory ovary in a morbidly obese 11-year-old girl: a case report. *Steven M Sharatz ... We report a case of what is best described as a giant serous cystadenoma arising from an accessory ovary in a morbidly obese 11 ...
more infohttps://jmedicalcasereports.biomedcentral.com/articles/10.1186/1752-1947-2-7

The Limitations of Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of Pancreatic Serous...The Limitations of Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of Pancreatic Serous...

Serous cystadenoma (SCA) is a rare, benign neoplasm that originates in the centro-acinar epithelium of the pancreas. Excluding ... Serous cystadenoma of the pancreas with endoscopic ultrasound fine needle aspiration biopsy and surgical correlation. Acta ... 9. Belsley NA, Pitman MB, Lauwers GY, Brugge WR, Deshpande V. Serous cystadenoma of the pancreas: limitations and pitfalls of ... 8. Huang P, Staerkel G, Sneige N, Gong Y. Fine-needle aspiration of pancreatic serous cystadenoma: cytologic features and ...
more infohttp://jpatholtm.org/journal/view.php?number=3302

Article - Imaging of the pancreas: Part 2Article - Imaging of the pancreas: Part 2

Serous cystadenoma (SCA) Also known as microcystic adenomas, serous cystadenomas do not have malignant potential. Therefore, ... The diagnosis of a serous cystadenoma can be made with confidence when a lesion demonstrates the classic imaging appearance of ... including a pseudocyst and serous cystadenoma. The fluid aspirated will contain thick mucin and an elevated level of tumor ...
more infohttps://appliedradiology.com/articles/imaging-of-the-pancreas-part-2

Passmedicine Flashcards by Gill Mill | BrainscapePassmedicine Flashcards by Gill Mill | Brainscape

Serous cystadenoma 8 If this ovarian tumour ruptures, it may cause pseudomyxoma peritonei ...
more infohttps://www.brainscape.com/flashcards/passmedicine-6817222/packs/10838598

Pancreatic Cysts - Mauna Kea TechnologiesPancreatic Cysts - Mauna Kea Technologies

Non-Mucinous - Serous cystadenoma. Cellvizio® provides real-time in vivo imaging Mucinous IPMN. Intraductal Papillary Mucinous ... Surveillance of serous cystadenomas is eliminated in 42% of cases.8. This allows for a 23% reduction in unnecessary surgeries.7 ... Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International ...
more infohttps://www.maunakeatech.com/int/cellvizio/39-pancreatic-cysts

Ovarian granulosa cell tumor - Answers on HealthTapOvarian granulosa cell tumor - Answers on HealthTap

Ovarian serous cystadenoma is cancer? Dr. Joseph Woods Dr. Woods 1 doctor agreed: ...
more infohttps://www.healthtap.com/topics/ovarian-granulosa-cell-tumor

Pancreatic cysts | Pancreatic Cancer UKPancreatic cysts | Pancreatic Cancer UK

Serous cystadenoma (also known as serous cystic neoplasm). Serous cystadenomas (SCAs) are non-cancerous cysts. They may be ...
more infohttps://www.pancreaticcancer.org.uk/information-and-support/facts-about-pancreatic-cancer/types-of-pancreatic-cancer/pancreatic-cysts/
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