Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Cystadenoma, Mucinous: A multilocular tumor with mucin secreting epithelium. They are most often found in the ovary, but are also found in the pancreas, appendix, and rarely, retroperitoneal and in the urinary bladder. They are considered to have low-grade malignant potential.Cystadenoma, Serous: A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972)Cystadenoma, Papillary: A benign neoplasm of the ovary.Cystadenocarcinoma: A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)Appendiceal Neoplasms: Tumors or cancer of the APPENDIX.Mucocele: A retention cyst of the salivary gland, lacrimal sac, paranasal sinuses, appendix, or gallbladder. (Stedman, 26th ed)Biliary Tract Neoplasms: Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Appendix: A worm-like blind tube extension from the CECUM.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Cysts: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.Sertoli-Leydig Cell Tumor: A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Adenolymphoma: A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.Cystadenocarcinoma, Mucinous: A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)Cecal Diseases: Pathological developments in the CECUM.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Spermatocele: A cystic dilation of the EPIDIDYMIS, usually in the head portion (caput epididymis). The cyst fluid contains dead SPERMATOZOA and can be easily differentiated from TESTICULAR HYDROCELE and other testicular lesions.Endocrine Gland Neoplasms: Tumors or cancer of the ENDOCRINE GLANDS.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Aspermia: A condition characterized by the complete absence of SEMEN. This disorder should be differentiated from AZOOSPERMIA, absence of sperm in the semen.Pseudomyxoma Peritonei: A condition characterized by poorly-circumscribed gelatinous masses filled with malignant mucin-secreting cells. Forty-five percent of pseudomyxomas arise from the ovary, usually in a mucinous cystadenocarcinoma (CYSTADENOCARCINOMA, MUCINOUS), which has prognostic significance. Pseudomyxoma peritonei must be differentiated from mucinous spillage into the peritoneum by a benign mucocele of the appendix. (Segen, Dictionary of Modern Medicine, 1992)Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Pancreatic Cyst: A true cyst of the PANCREAS, distinguished from the much more common PANCREATIC PSEUDOCYST by possessing a lining of mucous EPITHELIUM. Pancreatic cysts are categorized as congenital, retention, neoplastic, parasitic, enterogenous, or dermoid. Congenital cysts occur more frequently as solitary cysts but may be multiple. Retention cysts are gross enlargements of PANCREATIC DUCTS secondary to ductal obstruction. (From Bockus Gastroenterology, 4th ed, p4145)Urologic Surgical Procedures, Male: Surgery performed on the male genitalia.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Retroperitoneal NeoplasmsSalivary Glands, Minor: Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Pancreatic Pseudocyst: Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.Ovarian Cysts: General term for CYSTS and cystic diseases of the OVARY.Cholangiopancreatography, Magnetic Resonance: Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.Pancreatic Diseases: Pathological processes of the PANCREAS.Bile Ducts, Extrahepatic: Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).Appendectomy: Surgical removal of the vermiform appendix. (Dorland, 28th ed)Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Cystadenocarcinoma, Serous: A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)Adenocarcinoma, Mucinous: An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

Third International Meeting on von Hippel-Lindau disease. (1/27)

Five years after the identification of the von Hippel-Lindau (VHL) gene, physicians, scientists and concerned VHL family members met to review the current state of knowledge on the diagnosis and treatment of VHL and to summarize the latest information on the biochemistry of the VHL protein (pVHL). The NIH and University of Pennsylvania groups reported the detection of germ-line mutations in 100% (93 of 93) of VHL families studied. Several studies determined the frequency of VHL germ-line mutations in individuals with a single manifestation of VHL without a family history of VHL. National groups to improve the diagnosis and treatment of individuals with VHL disease have been established in Great Britain, Denmark, France, Holland, Italy, Japan, Poland, and the United States. Evidence for the existence of genes that modify the expression of VHL was presented. The VHL protein appears to have several distinct functions: (a) down-regulation of hypoxia-inducible mRNAs; (b) proper assembly of the extracellular fibronectin matrix; (c) regulation of exit from the cell cycle; and (d) regulation of expression of carbonic anhydrases 9 and 12.  (+info)

CDKN2A gene inactivation in epithelial sporadic ovarian cancer. (2/27)

The tumour suppressor gene CDKN2A, located on chromosome 9p21, encodes the cell cycle regulatory protein p16. Inactivation of the CDKN2A gene could lead to uncontrolled cell growth. In order to determine the role of CDKN2A in the development of sporadic ovarian cancer, loss of heterozygosity at 9p21-22, homozygous deletion, mutation and methylation status of the CDKN2A gene as well as CDKN2A expression were examined in a panel of serous papillary ovarian cancer. The frequency of loss of heterozygosity (LOH) for one or more informative markers at 9p21-22 was 65% (15/23). The most common deleted region was located between interferon (IFN)-alpha and D9S171. Homozygous deletions and mutations of the CDKN2A gene were not found. There was no evidence of methylation in exon 1, but methylation in exon 2 of CDKN2A gene was found in 26% (6/23). Absence of CDKN2A gene expression was shown in 27% (6/22) at mRNA level and 21% (4/19) at protein level. These data suggest that the CDKN2A gene is involved in the tumorigenesis of ovarian cancer, but the mechanisms of CDKN2A gene inactivation in serous papillary ovarian cancer remains unclear.  (+info)

Ovarian micropapillary serous borderline tumors. Clinicopathologic features and outcome of seven surgically staged patients. (3/27)

We report the clinicopathologic findings for 7 patients with completely staged ovarian micropapillary serous borderline tumors (MSBTs) to further clarify tumor behavior. None of the MSBTs had microinvasion in the ovarian neoplasm. The MSBT pattern constituted 25% to almost all of the neoplasm. Four were bilateral, and 6 involved the ovarian surface. Five patients had peritoneal implants; 2 were invasive, and 3 were noninvasive MSBTs. Distribution of stages among patients was as follows: IA, 1; IC, 1; IIC, 2; IIIB, 2; and IIIC, 1. Median follow-up was 8.5 years. Four patients were alive and well at the last follow-up visit, including 1 patient with stage IIIC (lymph node metastases) disease who had noninvasive implants (12 years after surgery). One patient who was free of disease died of complications of chemotherapy and abdominal surgery. Two patients died of intra-abdominal neoplastic growth (stages IIC and IIIB) 5 and 9 years after surgery, respectively; both had invasive implants. Without invasive peritoneal implants, MSBTs seem to behave as similar staged nonmicropapillary serous borderline tumors without invasive peritoneal implants. With invasive peritoneal implants, they seem to behave as low-grade carcinomas. Pathologists should recognize MSBT as a neoplasm that can have adverse prognostic features, including invasive peritoneal implants.  (+info)

Expression of laminin-5-gamma-2 chain in intraductal papillary-mucinous and invasive ductal tumors of the pancreas. (4/27)

The laminin-5-gamma-2 chain is expressed in various invasive carcinoma cells. To clarify the relationship between laminin-5 expression and the development of intraductal papillary-mucinous tumors (IPMTs), we performed an immunohistochemical study of 26 IPMTs and 30 invasive ductal adenocarcinomas. Cases were classified into five groups: intraductal papillary-mucinous adenoma (Group A; n = 8), adenocarcinoma without invasion (Group B; n = 3), adenocarcinoma with minimal invasion (Group C; n = 5), adenocarcinoma with macroscopically evident invasion (Group D; n = 10), and invasive ductal adenocarcinoma (conventional type; Group E; n = 30). In the invasive components of Groups D and E, laminin-5 was expressed in 80% and 100% of cases, respectively. In the intraductal components of IPMTs, expression of laminin-5 was not seen in Groups A and B, whereas they were seen in one case in Group C (20%) and in seven in Group D (70%). Most of the staining patterns of the intraductal components were focal and scattered. Laminin-5-gamma-2 expression in the intraductal components of IPMTs tends to increase as tumors develop and may be a indicator of the potential invasiveness of the tumor cells.  (+info)

Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations. (5/27)

Solid-pseudopapillary tumors (SPTs) are unusual pancreatic neoplasms of low malignant potential that most frequently affect young women. Genetic events contributing to the development of SPTs are unknown. Whereas the more common ductal adenocarcinomas of the pancreas essentially never harbor beta-catenin or APC gene mutations, we have recently identified alterations of the APC/beta-catenin pathway in other nonductal pancreatic neoplasms including pancreatoblastomas and acinar cell carcinomas. We analyzed a series of 20 SPTs for somatic alterations of the APC/beta-catenin pathway using immunohistochemistry for beta-catenin protein accumulation, direct DNA sequencing of beta-catenin exon 3, and direct DNA sequencing of the mutation cluster region in exon 15 of the APC gene in those SPTs that did not harbor beta-catenin mutations. Immunohistochemical labeling for cyclin D1 was performed to evaluate the overexpression of this cell-cycle protein as one of the putative downstream effectors of beta-catenin dysregulation. In addition, we analyzed the SPTs for genetic alterations commonly found in pancreatic ductal adenocarcinomas, including mutations in the K-ras oncogene and p53 and DPC4 tumor suppressor genes, using direct DNA sequencing of K-ras and immunostaining for p53 and Dpc4. Almost all SPTs harbored alterations in the APC/beta-catenin pathway. Nuclear accumulation of beta-catenin protein was present in 95% (19 of 20), and activating beta-catenin oncogene mutations were identified in 90% (18 of 20) of the SPTs. Seventy-four percent (14 of 19) showed overexpression of cyclin D1, ranging from 10 to 70% of tumor nuclei. In contrast, no K-ras mutations were present in any of the 20 SPTs, and Dpc4 expression was intact in all 16 SPTs for which immunohistochemical labeling was successful. Overexpression of p53 was limited to only 3 of 19 (15.8%) SPTs. These results emphasize the two distinct, divergent genetic pathways of neoplastic progression in pancreatic ductal and nonductal neoplasms.  (+info)

Solid--cystic papillary tumor of pancreas. (6/27)

A case of Solid and Cystic Papillary Epithelial Tumor of Pancreas displaying low grade malignancy occurring in a 38 years old female is presented. It is a rare condition and could be diagnosed histopathologically after complete excision.  (+info)

Differential diagnosis of benign and malignant intraductal papillary mucinous tumors of the pancreas: MR cholangiopancreatography and MR angiography. (7/27)

OBJECTIVE: To compare the usefulness of magnetic resonance cholangiopancreatography (MRCP) and MR angiography (MRA) in differentiating malignant from benign intraductal papillary mucinous tumors of the pancreas (IPMTs), and to determine the findings which suggest malignancy. MATERIALS AND METHODS: During a 6-year period, 46 patients with IPMT underwent MRCP. Morphologically, tumor type was classified as main duct, branch duct, or combined. The diameter of the main pancreatic duct (MPD), the extent of the dilated MPD, and the location and size of the cystic lesion, septum, and communicating channel were assessed. For all types of IPMTs, enhanced mural nodules and portal vein narrowing were evaluated at MRA. RESULTS: Combined-type IPMTs were more frequently malignant (78%) than benign (42%) (p < 0.05). Compared with benign lesions, malignant lesions were larger, and the caliber of the communicating channel was also larger (p < 0.05). Their dilated MPD was more extensive and of greater diameter (p < 0.05), and the presence of mural nodules was more frequent (p < 0.001). CONCLUSION: Combined MRCP and MRA might be useful for the differential diagnosis of malignant and benign IPMTs of the pancreas.  (+info)

Papillary cystadenoma arising from the upper lip: a case report. (8/27)

We report a rare case of a papillary cystadenoma arising from the upper lip. This tumor was not distinctly encapsulated and had proliferated replacing the ductal epithelium. Mast cells were found not only in the stroma but also in the oncocytic epithelial layer. There was a strong immunoreaction with mitochondrial antibody in the epithelial layer. Only one case (0.9%) of papillary cystadenoma has occurred among the 110 benign intraoral salivary gland tumors seen in our hospital from 1966 through September 2003.  (+info)

*Cystadenocarcinoma

Papillary serous cystadenocarcinoma "Female Genital Pathology". Retrieved 2009-03-23. King JC, Ng TT, White SC, Cortina G, ... Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from glandular epithelium, in which ...

*Pancreatic mucinous cystic neoplasm

Solid pseudopapillary neoplasm Pancreatic serous cystadenoma Intraductal papillary mucinous neoplasm Theruvath TP, Morgan KA, ...

*Pancreatic serous cystadenoma

In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and ... Pancreatic serous cystadenoma, also known as serous cystadenoma of the pancreas and serous microcystic adenoma, a benign tumour ... Ovarian serous cystadenoma Pancreatic mucinous cystadenoma Solid pseudopapillary neoplasm Colonna, J.; Plaza, JA.; Frankel, WL ... 2008). "Serous cystadenoma of the pancreas: clinical and pathological features in 33 patients". Pancreatology. 8 (2): 135-41. ...

*Papillary serous cystadenocarcinoma

... s may exhibit psammoma bodies upon histopathology. Papillary serous cystadenoma Papillary ... Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian ... Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ...

*Aldred Scott Warthin

Warthin, Aldred Scott (July 1929). "Papillary Cyst Adenoma Lymphomatosum: A Rare Teratoid of the Parotid Region". Journal of ... Adenolymphoma of the parotid gland, or papillary cystadenoma lymphomatosum, is better known as "Warthin's tumor"; he described ...

*Warthin's tumor

... , also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing ... The cystic spaces have epithelium referred to as papillary infoldings that protrude into them. Additionally, the epithelium has ...

*Forme fruste

... hand use is sometimes preserved with minimal stereotypic movements unilateral papillary cystadenoma is supposed to be forme ...

*List of MeSH codes (C04)

... cystadenoma MeSH C04.557.470.035.320.225 --- cystadenoma, mucinous MeSH C04.557.470.035.320.230 --- cystadenoma, papillary MeSH ... cystadenoma MeSH C04.557.470.590.485.225 --- cystadenoma, mucinous MeSH C04.557.470.590.485.230 --- cystadenoma, papillary MeSH ... papillary MeSH C04.557.470.200.025.085.225 --- carcinoma, papillary, follicular MeSH C04.557.470.200.025.095 --- adenocarcinoma ... papillary MeSH C04.557.470.200.400 --- carcinoma, squamous cell MeSH C04.557.470.200.400.130 --- bowen's disease MeSH C04.557. ...

*Testicular cancer

... structures Adenomatoid tumor Malignant and Benign Mesothelioma Adenocarcinoma of the epididymis Papillary cystadenoma of the ... types Serous tumor of borderline malignancy Serous carcinoma Well differentiated endometrioid tumor Mucinous cystadenoma ...

*Intraductal papillary mucinous neoplasm

Pancreatic mucinous cystic neoplasm Pancreatic serous cystadenoma Solid pseudopapillary neoplasm "Intraductal Papillary ... Intraductal papillary mucinous neoplasm (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN ... Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. As such IPMN is ... Once an intraductal papillary mucinous neoplasm has been found, the management options include close monitoring and pre-emptive ...

*Psammoma body

... carcinoma Papillary renal cell carcinoma Micropapillary subtype of lung adenocarcinoma Ovarian papillary serous cystadenoma and ... Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... The term is derived from the Greek word ψάμμος (psámmos), meaning "sand". Psammoma bodies are associated with the papillary ( ... Psammoma bodies are commonly seen in certain tumors such as: Papillary thyroid ...

*International Classification of Diseases for Oncology

NOS M8471/0 Papillary mucinous cystadenoma, NOS (C56.9) Papillary pseudomucinous cystadenoma, NOS M8471/3 papillary mucinous ... M8460/0 Papillary serous cystadenoma, NOS (C56.9) M8460/3 Papillary serous cystadenocarcinoma (C56.9) Papillary serous ... Eccrine cystadenoma M8405/0 Papillary hidradenoma Hidradenoma papilliferum M8406/0 Papillary syringadenoma (C44._) Papillary ... NOS Intraductal papillary carcinoma, NOS Ductal carcinoma in situ, papillary DCIS, papillary M8503/3 Intraductal papillary ...

*Cystadenoma

... serous cystadenoma (8441-8442) papillary cystadenoma (8450-8451, 8561) mucinous cystadenoma (8470-8473) Bile duct cystadenoma ( ... ISBN 1-4160-2999-0. Picture of serous cystadenoma Serous cystadenoma of pancreas at eMedicine Biliary cystadenoma/ ... 8161) Endometrioid cystadenoma (8380) Appendiceal mucinous cystadenoma The term "cystadenoma" may also refer to a hidrocystoma ... cystadenocarcinoma at eMedicine - Slide: Papillary Cystadenoma of Epididymis. ...

*Endolymphatic sac tumor

... papillary adenomatous tumor, aggressive papillary adenoma, invasive papillary cystadenoma, and papillary tumor of temporal bone ... Aug 1993). "Papillary neoplasms (Heffner's tumors) of the endolymphatic sac". Ann Otol Rhinol Laryngol. 102 (8 pt 1): 648-51. ... The tumor is arranged as simple, broad, non-complex papillary projections without large cystic spaces. The spaces are often ... The cells are cuboidal, usually single layered along the papillary structures, showing indistinct cell borders. The nuclei are ...

*Von Hippel-Lindau disease

... pancreatic serous cystadenoma), endolymphatic sac tumor, and bilateral papillary cystadenomas of the epididymis (men) or broad ...

*Pancreatectomy

Cystadenoma (mucinous/serous) Cystadenocarcinoma Islet cell tumors (neuroendocrine tumors) Papillary cystic neoplasms Lymphoma ...

*Cystic lesions of the pancreas

Pancreatic intraductal papillary mucinous tumors (most common diagnosis - 52.6%) Pancreatic serous cystic tumors (20.6%) ... Pancreatic mucinous cystadenoma Pancreatic mucinous cystadenocarcinoma Parra-Herran, C. E.; Garcia, M. T.; Herrera, L; Bejarano ... Pancreatic serous cystadenoma Pancreatic serous cystadenocarcinoma Pancreatic mucinous cystic tumors (13.4%) ...

*Serous carcinoma

Uterine serous carcinoma, also known as uterine papillary serous carcinoma, a type of uterine cancer. Fallopian tube serous ... Serous tumour Cytopathology Ovarian serous cystadenoma Mesothelioma Serous Membranes & Cavities Lecture. Veterinary Anatomy Web ...

*Serous tumour

On gross examination, the serous tumor may present as either a cystic lesion in which the papillary epithelium is contained ... Sixty percent are benign (cystadenoma), 10% are borderline and 30% are malignant (cystadenocarcinoma). Benign serous tumours ... In borderline lesions, the cyst or surface is lined by papillary structures, which are often very complex. Surgery is usually ... They are lined by a complex papillary pattern with presence of nuclear anaplasia. Serous carcinomas often have bulky peritoneal ...

*Pancreatic disease

Cysts also may be present due to intraductal papillary mucinous neoplasm. Pancreas divisum is a malformation in which the ... See pancreatic tumors, benign or malignant (pancreatic cancer). Serous cystadenoma of the pancreas Solid pseudopapillary ...

*Hereditary leiomyomatosis and renal cell cancer syndrome

The renal cell carcinoma tends to be of the papillary (type 2) form and tends to occur more commonly in women than men with ... Two cases of ovarian mucinous cystadenoma have also been reported with this mutation. The fumarate hydratase gene, located on ... skin leiomyomata and papillary renal cell cancer". Nature Genetics. 30 (4): 406-410. doi:10.1038/ng849. PMID 11865300. Bayley, ... "Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type ...

*Surgical Outcomes Analysis and Research

Simons JP, Ng SC, Shah SA, McDade TP, Whalen GF, Tseng JF (2009). "Malignant Intraductal Papillary Mucinous Neoplasm: Are We ... Tseng JF (March 2008). "Management of serous cystadenoma of the pancreas". J. Gastrointest. Surg. 12 (3): 408-10. doi:10.1007/ ...

*List of cutaneous conditions

Aggressive digital papillary adenocarcinoma (digital papillary adenocarcinoma, papillary adenoma) Apocrine gland carcinoma ... cystadenoma, Moll's gland cyst, sudoriferous cyst) Hydrocarbon keratosis (pitch keratosis, tar keratosis, tar wart) ... malignant endovascular papillary angioendothelioma, papillary intralymphatic angioendothelioma) Epithelioid cell histiocytoma ... Paget's disease of the breast Papillary eccrine adenoma (tubular apocrine adenoma) Papillary hidradenoma (hidradenoma ...

*Ovarian cancer

... cystadenoma (serous or mucinous), diverticular or appendiceal abscess, nerve sheath tumor, pelvic kidney, ureteral or bladder ... with gland-like spaces and papillary structures. Polyembryomas, the most immature form of teratoma and very rare ovarian tumors ... and they typically have papillary features, central vessels, and/or irregular internal septations. However, SCST has no ...
Welcome to the updated version of Pathology for Urologists! This program was designed to help Urology residents and fellows familiarize themselves with the pathologic features of common urologic entities. This will serve not only as a resource tool for your review but also as a quick reference guide to urologic pathology.
Solid pseudopapillary tumors (SPTs) are unusual neoplasms that mostly occur in the pancreas, and predominantly affect young women. As a low-grade malignant neoplasm of the exocrine pancreas, they occasionally metastasize, usually to the liver or peritoneum. It has been reported that ,1% of SPTs are primary extrapancreatic SPTs. In the present study, we present two rare, but conspicuous extrapancreatic SPTs. Both occurred in young women, and showed good prognoses following surgery. One was a recurrent SPT of the pancreas that metastasized to the ovary, and the other was a distinct primary neoplasm that arose in the retroperitoneal area. The pathological features of the two tumors, including solid and pseudopapillary growth patterns with pale or eosinophilic cytoplasm, were characteristic of SPTs of the pancreas. However, in the case of the metastatic ovarian tumor, focal necrosis and an increased nuclear-to-cytoplasmic ratio were observed. The presence of positive nuclear-cytoplasmic β-catenin, ...
Solid pseudopapillary tumor of the pancreas (SPTP) is a rare pancreatic tumor. Rarely does the tumor have a multicentric location. We report this unusual case of a 24-year-old woman who had 2 large synchronous SPTPs detected incidentally by routine p
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
A Free portal for dental pg aspirants,BDS graduates. High Yield Points, Strategies with respect to the Indian Medical Post Graduate PG Entrance Exams like AIIMS,AIPG, JIPMER, CMC Vellore, PGI Chandigarh, UPSC, TNPSC, State PG Exams like Delhi PG, UPPG, Tamilnadu PG (TNPG), Karnataka PG etc.
Dr. Adaia Valls talks to us about the following news: Prognosis of Tumours Positive for Human Papilloma Virus in Head and Neck Cancers Vary According to the Site.. The Human Papilloma Virus generally affects the superficial tissue in the skin and the mucous membranes in the human body. There are currently around 200 types of HPV that, in most cases, produce a benign epithelial proliferation that appears as warts or condylomas.. Although a high number of studies have proved that positive HPV oropharyngeal tumours have a better prognosis than the negative ones, further investigation needs to be carried out in order to establish new, less aggressive and equally efficient guidelines to treat this type of tumours.. ...
Cystic tumors of the pancreas today are diagnosed more frequently in clinical practice, mainly due to an increased use of the modern advanced imaging modalities.. Bland cysts of the pancreas most often develop after chronic or acute inflammation of the pancreas. However, the current knowledge concerning the development of cystic neoplasias of the pancreas is still rudimentary.. Histopathologically, 90% of pancreatic cystic neoplasias are represented by four types: serous microcystic (SCN), mucinous cystic (MCN), intraductal papillary mucinous (IPMN) and solid pseudopapillary (SPN) neoplasias. Surgical treatment of these lesions can be highly challenging and occasionally demands complex surgical approaches that should be put in the hands of skilled pancreatic surgeons in experienced high-volume centers.. While some of the described cystic tumors are harmless, such as SCNs of the pancreas, others such as IPMN and MCN harbor relevant malignant potential. The differential diagnosis of these lesions ...
Risk of Malignancy in Unilocular Ovarian Cystic Tumors Less Than 10 Centimeters in Diameter Susan C. Modesitt, MD, Edward J. Pavlik, PhD, Frederick R. Ueland, MD, Paul D. DePriest, MD, R. J. Kryscio, PhD,
We report a hitherto not documented case of primary mucinous cystadenoma arising in the spermatic cord within the right inguinal canal of a78-year-old man. The tumor was painless, hard and mobile. A computed tomography scan on the pelvis revealed an
Pancreatic schwannoma is a rare tumor. Preoperative diagnosis of pancreatic schwannoma is challenging due to its tendency to mimic other lesions of the pancreas. We describe a case of pancreatic schwannoma and present a review of the cases currently reported in the English literature to identify characteristics of pancreatic schwannoma on imaging. A 53-year-old male presented with a history of intermittent periumbilical abdominal pain and lower back pain for 1 week. Based on ultrasound (US) and computed tomography (CT) findings, we made a preoperative diagnosis of solid pseudopapillary tumor and performed a standard pancreaticoduodenectomy. Pathological examination showed that the tumor was composed of spindle cells with a palisading arrangement, and immunohistochemistry revealed strong positive staining for S-100 protein, which was consistent with a diagnosis of pancreatic schwannoma. At the 8-month follow-up visit, the patient was doing well without recurrent disease, and his abdominal pain had
小林 剛 , 藤田 直孝 , 野田 裕 , 木村 克巳 , 渡邊 浩光 , 長南 明道 , 松永 厚生 , 結城 豊彦 , 安藤 正夫 , 佐藤 自伸 , 富永 現 , 望月 福治 , 山崎 匡 日本消化機病學會雜誌. 乙 90(12), 3081-3089, 1993 J-STAGE 医中誌Web 被引用文献20件 ...
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Amphetamine definition, a racemic drug, C 9 H 13 N, that stimulates the central nervous system: used chiefly to lift the mood in depressive states and to control the appetite in cases of obesity. See more.
TY - JOUR. T1 - High yields of K-ras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine in the pancreas of female Syrian hamsters. AU - Sugio, Kenji. AU - Gazdar, Adi F.. AU - Albores-Saavedra, Jorge. AU - Kokkinakis, Demetrius M.. PY - 1996. Y1 - 1996. N2 - Ductal adenocarcinoma, the most common form of pancreatic cancer in humans, is associated with activation of the K-ras oncogene in ~90% of cases. In contrast, K-ras mutations are found in ,50% of the relatively rare intraductal papillary mucinous tumor (IPMT), which arises in the main pancreatic ducts. Since both adenocarcinomas and IPMTs are believed to arise from ductal cells and progress through similar sequences of morphological changes (i.e. flat hyperplasia, papillary hyperplasia, atypia and carcinoma in situ), it is clear that such progression may not always necessitate activation of the ras oncogene. Experimentally ductal adenocarcinomas of the ...
TY - JOUR. T1 - Invasive cancer and survival of intraductal papillary mucinous tumors of the pancreas. AU - Raimondo, Massimo. AU - Tachibana, Issei. AU - Urrutia, Raul. AU - Burgart, Lawrence J.. AU - DiMagno, Eugene P.. PY - 2002/10/1. Y1 - 2002/10/1. N2 - OBJECTIVES: Intraductal papillary mucinous tumor (IPMT) is frequently associated with pancreatic cancer. We hypothesized that IPMT progresses to invasive cancer with K-ras mutations as an early event, and that invasive cancer affects survival. We compared survival after resection and determined whether K-ras mutations predicted survival in IPMT patients without or with invasive cancer. METHODS: Records of 47 patients with IPMT who were seen between 1983 and 1998 were reviewed retrospectively in 15 cases and prospectively in 32. All histological material was reviewed to confirm the diagnosis of IPMT and to assess invasion. Kaplan-Meier survival curves were analyzed by the log-rank test. The X2 test was used for differences in K-ras between ...
Looking for pseudomucinous cystadenoma? Find out information about pseudomucinous cystadenoma. A benign ovarian tumor composed of columnar mucin-producing cells lining multilocular cysts filled with mucinous material Explanation of pseudomucinous cystadenoma
Solid pseudopapillary neoplasm of the pancreas with prominent atypical multinucleated giant tumour cells.s profile, publications, research topics, and co-authors
Looking for online definition of cystic tumor in the Medical Dictionary? cystic tumor explanation free. What is cystic tumor? Meaning of cystic tumor medical term. What does cystic tumor mean?
The mean age of patients with typical SBT is reported to be 42 years (range, 36.8 to 43 years), whereas that of patients with SBT-MP is 45 years, which is younger than patients with serous carcinoma. In our series the mean age was 26.3 years, which is much younger than patients with typical SBT or SBT-MP. Furthermore, the FIGO (International Federation of Gynecology and Obstetrics) stage of SBT-MP was stage II with noninvasive intrapelvic implants in two patients and stage III with noninvasive peritoneal implants in two patients. Considering that 65-80% of patients with typical SBT are in stage I, the stage of SBT-MP is more advanced than that of typical SBT, illustrating the aggressive feature. LGSC characterized by KRAS, BRAF, and ERBB2 gene mutations is thought to show stepwise progression and develop from serous cystadenomas and SBT [8-10]. In fact, histopathological analyses revealed transformation zones from typical SBT in several places in our series (Fig. 3e).. The current WHO ...
A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed ...
SPEN(Solid and papillary epithelial neoplasm of pancreas) 10-20대 여성(흑인)에서 주로 발생, low malignant potential * CT : large cystic tumor of pancreas * Gross : solitary, large(8-10cm), pseudocapsule cross-section: solid & cystic component 내부에 hemorrhage & necrosis동반 * Micro : uniform eosinophilic granular cytoplasm round to oval nuclei with indistinct nucleoli mitotic rate↓ IPMT(Intraductal papillary mucinous tumor) = mucinous ductal ectasia pancreas head에 주로 생기고 남자에 많다. pancreatitis를 잘 일으키며 ERCP상 duct dilatation내에 filling defect(mucin)으로 나타난다. ERCP에서 ampulla of Vater로 mucin이 흘러내리는 것을 관찰할수 있다. premalignant lesion으로 수술적 절제가 필요하다. mucin fluid에 CA 19-9가 증가해 있다. Cystic neoplasm serous & mucinous cystic neoplasm의 두 종류가 있으며 serous neoplasm은 benign, mucinous neoplasm은 premalignant lesion이다. 둘다 중년 여성에 많고, ...
Spontaneous rupture of mucinous cystadenoma of the pancreas - Grand Rounds Spontaneous rupture of mucinous cystadenoma of the pancreas - Pancreatic cysts that develop after abdominal trauma are generally considered to be pseudocysts. We present a patient with a post-traumatic peri-pancreatic cyst that later ruptured suddenly, leading to an acute abdomen. Following an urgent laparotomy and excision of the cyst, post-operative histopathological assessment showed this to be a mucinous cystadenoma of the pancreas. We have reviewed the literature on spontaneous rupture of mucinous cystadenomas of the pancreas.
Histologically, cystoadenomas are characterised by the presence of cysts lined with mucinous cuboidal or columnar epithelium.6 An ovarian-type stroma is seen in 85% of cases and exclusively in females.4 A marsupial pseudocapsule separates the cystadenoma from the biliary epithelium.4 Elevated levels of CA 19-9 and/or CEA have been reported within the cysts themselves.1 2 4 11 12. Although the biliary cystadenoma is a benign entity, malignant transformation can occur, leading to cystadenocarcinoma.4 Sarcomatous transformation has also been described in one case.6 It has been suggested that cystadenocarcinomas arising from biliary cystadenomas with ovarian-type stroma have a relatively indolent course, whereas cystadenomas without ovarian-type stroma have a poorer prognosis.4. Most commonly, on radiologic imaging, these neoplasms appear as multi-loculated, multi-septated intrabiliary neoplasms. They are usually large at the time of presentation, with a mean tumour size of 15 centimetres.4 On CT, ...
Mucinous cystadenoma is a type of tumor that usually develops in the ovaries, pancreas, or appendix. Its typically benign, but...
A 53-yr-old woman with a history of hepatic cystadenoma 25 yr before presented with a simple hepatic cyst, which evolved over 9 yr into a complex cystadenoma with septations and internal bleeding. She was treated with a left hepatectomy. Review of the literature shows that hepatic cystadenomas, although rare, frequently can recur years later and have potential for malignant transformation. Histologic similarities of one variant with ovarian stroma raises interesting possibilities regarding the origin of these lesions. The best treatment results are obtained with radical excision ...
Causes of ovarian serous cystadenoma - What causes an ovarian serous cystadenoma to rupture do I need surgery if rupture? Pressure. The increased pressure and weak wall of the ovary can cause it to rupture - you do not need surgery if it does. You might consider getting it removed before it does though.
When we examined solid pseudopapillary tumours of the pancreas, a tumour characterised by β‐catenin mutations within exon 3, these tumours showed a strong reduction in E‐cadherin:β‐catenin complexes. Moreover in HCC, a tumour type which has approximately 20% β‐catenin exon 3 mutations, there was a good correlation between reduction in E‐cadherin and activation of Wnt signalling targets. Thus, it may be that in these cancers, E‐cadherin limits the precise levels of Wnt signalling driven by β‐catenin mutation. Thus, downregulation of E‐cadherin in these tumours may drive tumour progression. It should also be noted that opposing patterns of Wnt signalling and E‐cadherin have been shown in murine liver, with β‐catenin higher in zone 3 of the liver and E‐cadherin in zone 1. Therefore, one might predict that β‐catenin mutations would yield a greater phenotype in hepatocytes from zone 3 of the liver versus zone 1 (Benhamouche et al, 2006). Hence, one could speculate ...
The paratesticular scrotal contents consist of the spermatic cord, epididymis, and fascia, which originate from the embryologic descent of the testis through the abdominal wall. Historically, the primary diagnostic modality has been high-resolution ultrasound. Magnetic resonance imaging (MRI) is an alternative imaging option. Both contrast MRI and diffusion weighted imaging can assist in differentiating between benign and malignant lesions. Unlike the testis which most disease processes are malignant, a wide spectrum of benign disease processes affects the paratesticular region either in isolation or as part of a contiguous disease process from adjacent organs. The familiarity with the epidemiology, pathogenesis, and imaging features can aid the radiologic diagnoses and guide appropriate clinical management. In this article, we review the ultrasound and MR characteristics of various paratesticular pathologies.
Brain Development The shaky pattern continues to knowledgeable everywhere early, and the developing in ceo circumference is indicative of wit growth. Shifting Responsibilities From Hospital-Based to Community-Based Nursing Care Over the sometime century changes in vigorousness attention, such as uncomfortable salubrity care funding, shorter asylum stays, and sell for containment, include led to a make it in responsibilities of care payment children from the infirmary to homes and communities. Chemic toxins are each approximately you in cleansing supplies, pesticides, herbicides, and matter additives generic 30 gm himcolin with mastercard natural erectile dysfunction treatment remedies. Patterns of p53 mutations partition ovarian serous borderline tumors and low- and high-grade carcinomas and provide keep proper for a new prototype of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation. Non-critical stimulation coupled effects (viscerosensory symptoms, cough, ...
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary. Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b. ...
A cystic tumor of the ovary either nonneoplastic (follicle, lutein, germinal inclusion, or endometrial) or neoplastic; either benign (pseudomucinous or serous cystadenoma, or dermid) or malignant (carcinoma ...
Mini-Chromosome Maintenance protein 7 (MCM7) is involved in replicative licensing and synthesis of DNA. It is previously identified as over-expressed gene in high-grade serous carcinomas compared to serous borderline tumors of the ovary in cDNA microarray studies. In this study, we sought to validate MCM7 expression in ovarian tumors by applying immunohistochemical analysis on tissue microarrays consisting of 445 ovarian tumors. MCM7 expression was quantified as MCM7 labeling index by determining the tumor nuclei positive for MCM7 staining as a percentage of total tumor nuclei. The labeling index scores were independently generated by two methods: PATH score provided by a manual review of each samples by a pathologist and ACIS score provided by Automated Cell Imaging System. Analyses of both scores indicated high degree of concordance in score distribution between PATH and ACIS. MCM7 expression is significantly higher in high-grade serous carcinomas compared to serous borderline tumors, ...
Robot-Assisted Laparoscopic Vesiculectomy for Large Seminal Vesicle Cystadenoma: A Case Report and Review of the Literature. ( 25862321 ) ...
Given its size, solid components, and enhancment characteristics, surgical excision was recommended. Differential considerations Ovarian cystadenofibroma Ovarian cystadenocarcinoma Sclerosing stromal tumor of the ovary Ovarian masses with f...
Figure 1: Morphologic appearances of mucinous cystadenoma and mucinous cystadenocarcinoma. The cytological atypia is minimal in both entities. Mucinous cystadenoma (A) and Mucinous cystadenocarcinoma (B ...
Biliary cystadenomas are uncommon benign cystic neoplasms of the liver. Epidemiology Biliary cystadenomas occur predominantly in middle-aged patients and are more common in women 1. Clinical presentation The clinical presentation of biliary c...
Murthy, V., Fisher, C., Horwich, A. (2006) Rare tumours of the testis and paratesticular tissues. In: Textbook of uncommon cancers (3rd ed.). Wiley, West Sussex, UK, pp. 66-85. ISBN 978-047001202-4 ...
I have rung up today and booked Bob in for his operation. Its going to be on Tuesday 13th July. I have to drop him off about 9am. Big crossed fingers for him after what happened to Beau. I will make sure he gets stitched internally and externally along with the inguinal canals being stitched…
For patient information click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2] Synonyms and Keywords: Cystadenoma of biliary tract; Cystadenoma of biliary tree; Cystadenoma of biliary system; Biliary cystadenomas; Hepatobiliary cystadenoma; Intrahepatic bile duct cystadenoma; Cystadenocarcinoma of biliary tract; Cystadenocarcinoma of biliary tract; Intrahepatic bile duct cystadenocarcinoma; Hepatobiliary cystadenocarcinoma; Cystadenocarcinoma of biliary system ...
Mucinous cystadenoma is a type of cystic neoplasm. This type of tumor is usually benign when small but can grow and degenerate into a frank cancer. Most patients with these tumors are in their 5th and 6th decade and it is more common in women. Most of these tumors occur in the body and tail of the pancreas. As with serous cystadenomas they can usually be definitely diagnosed with modern diagnostic testing. When small (,3cm) and asymptomatic, most experts feel these lesions can be safely observed provided there is close surveillance with CT scans. If the lesion is ,3cm, causing symptoms or obstructing the pancreatic duct they should be surgically excised. Even if a cystadenocarcinoma is found, the prognosis is quite good if the tumor can be surgically removed.. ...
The main objective of this study was to characterize the expression of the NaPi2b in ovarian tumor samples. The development, evaluation and optimization of the targeted antibody treatment for this patient group call for a more detailed characterization of the cancer cell antigen expression. Our results from this study complement the present knowledge of NaPi2b expression in epithelial ovarian cancer and ovarian borderline tumors.. With 93% of the ovarian cancer tissue samples positively stained our data shows a higher frequency of NaPi2b expression compared to a study performed by Lopes dos Santos et al. where 80% of the ovarian cancers express the protein [10]. Among the samples positive for NaPi2b the samples were evenly distributed between the staining intensities. All of the type 2 tumors were positive for NaPi2b and three out of four tumors had moderate or strong staining. Strong staining was more frequent among the serous borderline tumors, which is promising if targeted antibody based ...
This post will examine the nature of ovarian cystadenomas as well as their symptoms and treatment. What are cystadenomas? Cystadenomas are a type of cystic adenoma meaning a cystic growth or tumor. They can form in various parts of the body, in
Collaud, St phane et al. Mucinous cystadenoma arising in a completely isolated infected ileal duplication cyst. S. Afr. j. surg., May 2012, vol.50, no.2, p.45-46. ISSN 0038- ...
Cystadenoma most often occurs in middle-aged women. However, cystadenocarcinoma equally affects both men and women. Most patients are asymptomatic or have vague abdominal complaints of bloating, nause... more
TY - JOUR. T1 - Comprehensive genetic characterization of human thyroid cancer cell lines. T2 - A validated panel for preclinical studies. AU - Landa, Iñigo. AU - Pozdeyev, Nikita. AU - Korch, Christopher. AU - Marlow, Laura A.. AU - Smallridge, Robert Christian. AU - Copland, John A III. AU - Henderson, Ying C.. AU - Lai, Stephen Y.. AU - Clayman, Gary L.. AU - Onoda, Naoyoshi. AU - Tan, Aik Choon. AU - Garcia-Rendueles, Maria E.R.. AU - Knauf, Jeffrey A.. AU - Haugen, Bryan R.. AU - Fagin, James A.. AU - Schweppe, Rebecca E.. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Purpose: Thyroid cancer cell lines are valuable models but have been neglected in pancancer genomic studies. Moreover, their misidentification has been a significant problem. We aim to provide a validated dataset for thyroid cancer researchers. Experimental Design: We performed next-generation sequencing (NGS) and analyzed the transcriptome of 60 authenticated thyroid cell lines and compared our findings with the known genomic defects ...
2. When you see a multilocular cyst with a central scar, think of a serous cystadenoma; if it is absent, think of a mucinious cystadenoma. Both are " NOT" connected to the main pancreatic ductal ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
The two most common cystic neoplasms of the pancreas are serous cystadenoma (which is benign )and mucinous cystic neoplasms.Serous cystadenoma is more common than mucinous cystic neoplasm, with a ratio of about 2:1. Intraductal papillary mucinous tumor (IPMT) is a more recently discovered cystic neoplasm that may be a variant of the mucinous cystic neoplasm (biologic behavior of mucinous cystic neoplasm and IPMT ranges from benign to malignant ...
Persistent RET activation is a frequent event in papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC). In these cancers, RET activates the ERK/MAPK, the PI3K/AKT/mTOR and the JAK/STAT3 pathways. Here, we tested the efficacy of a JAK1/2- inhibitor, AZD1480, in the in vitro and in vivo growth of thyroid cancer cell lines expressing oncogenic RET. Thyroid cancer cell lines harboring RET/PTC1 (TPC-1), RET M918T (MZ-CRC1) and RET C634W (TT) alterations, as well as TPC-1 xenografts, were treated with JAK inhibitor, AZD1480. This inhibitor led to growth inhibition and/or apoptosis of the thyroid cancer cell lines in vitro, as well as to tumor regression of TPC-1 xenografts, where it efficiently blocked STAT3 activation in tumor and stromal cells. This inhibition was associated with decreased proliferation, decreased blood vessel density, coupled with increased necrosis. However, AZD1480 repressed the growth of STAT3- deficient TPC-1 cells in vitro and in vivo, demonstrating that its effects
The laparoscopic approach in distal pancreatectomy is associated with higher rates of splenic preservation compared to open surgery. Although favorable pos
TY - JOUR. T1 - Contralateral testicular metastasis in paratesticular rhabdomyosarcoma. AU - Backhaus, Björn O.. AU - Kaefer, Martin. AU - Engum, Scott A.. AU - Davis, Mary M.. PY - 2000. Y1 - 2000. KW - Neoplasm metastasis. KW - Rhabdomyosarcoma. KW - Testis. KW - Ultrasonography. UR - http://www.scopus.com/inward/record.url?scp=0033793373&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0033793373&partnerID=8YFLogxK. M3 - Article. C2 - 11025756. AN - SCOPUS:0033793373. VL - 164. SP - 1709. EP - 1710. JO - Journal of Urology. JF - Journal of Urology. SN - 0022-5347. IS - 5. ER - ...
Cystic, mucinous, and serous neoplasms is a group of tumors. An example is cystadenoma. Cyst Mucinous, Mucous gland Serous, Serous ...
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iii. In vaginal type the swelling is limited to scrotum. In congenital type one cant go above the swelling. In infantile type the swelling ends in inguinal canal and one can go above the swelling. ...
iii. In vaginal type the swelling is limited to scrotum. In congenital type one cant go above the swelling. In infantile type the swelling ends in inguinal canal and one can go above the swelling. ...

Causes of ovarian serous cystadenoma - Things You Didnt KnowCauses of ovarian serous cystadenoma - Things You Didn't Know

What causes an ovarian serous cystadenoma to rupture do I need surgery if rupture? Pressure. The increased pressure and weak ... Ovarian serous cystadenoma and treatment * Carboplatin only for serous carcinoma papillary ovarian cancer ... Yes possible: It is possible longstanding cystadenoma some times can transform to malignant cystadenoma, pathologically it is ... Yes possible: It is possible longstanding cystadenoma some times can transform to malignant cystadenoma, pathologically it is ...
more infohttps://www.healthtap.com/topics/causes-of-ovarian-serous-cystadenoma

Pathology Outlines - Papillary cystadenomaPathology Outlines - Papillary cystadenoma

Vascular endothelial growth factor in von Hippel-Lindau syndrome - associated papillary cystadenoma of epididymis (Hum Pathol ... Papillary in foldings project into cystic spaces covered by single to double layered cuboidal / columnar cells *Tubules common ... Useful negative stains include AMACR and RCC antigen, to differentiate from clear cell papillary renal cell carcinoma *CD10 is ... Simple and complex papillary clusters *Tumor cells are monomorphic, with moderate to abundant cytoplasm, well defined ...
more infohttps://www.pathologyoutlines.com/topic/testisepidpapcyst.html

Mesonephric (Wolffian) Pseudoendometrioid Carcinoma of the Broad Ligament, Arising From a Papillary CystadenomaMesonephric (Wolffian) Pseudoendometrioid Carcinoma of the Broad Ligament, Arising From a Papillary Cystadenoma

... ... carcinoma lies in the fact that its mesonephric nature is revealed by the origin from a papillary cystadenoma of the broad ...
more infohttps://insights.ovid.com/ijsup/201610000/00045438-201610000-00012

Laparoscopic Anatomical Left Hepatectomy for Intrahepatic Bile Duct Papillary Mucinous Cystadenoma With Intraoperative Vascular...Laparoscopic Anatomical Left Hepatectomy for Intrahepatic Bile Duct Papillary Mucinous Cystadenoma With Intraoperative Vascular...

Laparoscopic Anatomical Left Hepatectomy for Intrahepatic Bile Duct Papillary Mucinous Cystadenoma With Intraoperative Vascular ...
more infohttps://insights.ovid.com/medi/201602090/00005792-201602090-00087

Bilateral Papillary Cystadenoma of the Epididymis, Sensorineural Hearing Loss Associated with ELSTs, X-Ray Abnormal: Causes &...Bilateral Papillary Cystadenoma of the Epididymis, Sensorineural Hearing Loss Associated with ELSTs, X-Ray Abnormal: Causes &...

Possible causes include Papillary Cystadenoma of the Kidney, Von Hippel-Lindau Disease, Renal Cell Carcinoma. Check the full ... Bilateral Papillary Cystadenoma of the Epididymis, Sensorineural Hearing Loss Associated with ELSTs, X-Ray Abnormal Symptom ... Genitourinary Internal Genitalia Male: epididymal cyst bilateral papillary cystadenoma of the epididymis bilateral papillary ... Papillary Cystadenoma of the Kidney […] fields, not x-rays, to produce detailed images of the body.[cancer.net] […] sac tumor, ...
more infohttps://www.symptoma.com/en/ddx/bilateral-papillary-cystadenoma-of-the-epididymis+sensorineural-hearing-loss-associated-with-elsts+x-ray-abnormal

Introduction Warthins tumor, also known as papillary cystadenoma lymphomatosum, monomorphic adenoma, | Discovery and...Introduction Warthins tumor, also known as papillary cystadenoma lymphomatosum, monomorphic adenoma, | Discovery and...

Introduction Warthins tumor, also known as papillary cystadenoma lymphomatosum, monomorphic adenoma,. *Acetylcholine ??4??2 ... Introduction Warthins tumor, also known as papillary cystadenoma lymphomatosum, monomorphic adenoma, or adenolymphoma, is a ...
more infohttp://www.monossabios.com/2019/05/13/introduction-warthins-tumor-also-known-as-papillary-cystadenoma-lymphomatosum-monomorphic-adenoma/

Serous cystadenoma (simple and papillary) - All information about cystsSerous cystadenoma (simple and papillary) - All information about cysts

... and papillary (or papillary) cystadenoma. On the inner surface of the latter there are small dense growths resembling warts. ... Papillary cystadenoma may contain not one but several cavities (chambers), often affects both ovaries. All these features make ... Papillary cystadenoma ovary sometimes gives the accumulation of fluid in the abdomen (ascites), which also leads to its ... Serous cystadenoma (simple and papillary). September 15, 2015 by Adam Cooper · September 15, 2015 ...
more infohttps://allcysts.com/serous-cystadenoma-simple-and-papillary/

Benign Parotid Tumors: Significance, Anatomy, Incidence and EtiologyBenign Parotid Tumors: Significance, Anatomy, Incidence and Etiology

Warthin tumor (papillary cystadenoma lymphomatosum or adenolymphoma). See the list below:. * Second most common benign parotid ...
more infohttps://emedicine.medscape.com/article/1289560-overview

Chapter 11 Flashcards by Ryan Davis | BrainscapeChapter 11 Flashcards by Ryan Davis | Brainscape

Warthins tumor (papillary cystadenoma lymphomatosum). These occur almost exclusively in the parotid gland and may be bilateral ...
more infohttps://www.brainscape.com/flashcards/chapter-11-6157970/packs/9500262

11 Salivary Gland Diseases Flashcards by Jordan Sanger | Brainscape11 Salivary Gland Diseases Flashcards by Jordan Sanger | Brainscape

Warthins tumor (papillary cystadenoma lymphomatosum). 70 Who has an 8-fold higher risk of developing warthins tumor? ...
more infohttps://www.brainscape.com/flashcards/11-salivary-gland-diseases-5331260/packs/7708071

von Hippel-Lindau Disease - Massachusetts General Hospital, Boston, MAvon Hippel-Lindau Disease - Massachusetts General Hospital, Boston, MA

Epididymal papillary cystadenoma. *Pancreatic serous cystadenomas. *Pancreatic neuroendocrine tumors. Why should those at risk ...
more infohttp://www.massgeneral.org/cancer/about/newsarticle.aspx?id=2550

Bajpai M[au] - PubMed - NCBIBajpai M[au] - PubMed - NCBI

Oncocytic Papillary Cystadenoma of Parotid Gland.. Bajpai M, Pardhe N, Kumar M. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Bajpai+M%5Bau%5D&dispmax=50

Diagnosis of Salivary Gland Disorders Buch portofrei - Weltbild.deDiagnosis of Salivary Gland Disorders Buch portofrei - Weltbild.de

Papillary cystadenoma lymphomatosum (Warthins tumor).- 7.4. Malignant salivary gland lesions.- 7.4.1. Adenoid cystic carcinoma ...
more infohttps://www.weltbild.de/artikel/buch/diagnosis-of-salivary-gland-disorders_16096014-1

Salivary Gland Cancer: Subtypes | Cancer.NetSalivary Gland Cancer: Subtypes | Cancer.Net

Papillary cystadenoma lymphomatosum (Warthins tumor). * Oncocytoma. * Monomorphic adenoma, including basal cell adenoma, ...
more infohttps://www.cancer.net/cancer-types/salivary-gland-cancer/subtypes

Category:Epididymis - Wikimedia CommonsCategory:Epididymis - Wikimedia Commons

Papillary cystadenoma of epididymis‎ (1 C, 1 F). Media in category "Epididymis". The following 4 files are in this category, ...
more infohttps://commons.wikimedia.org/wiki/Category:Epididymis

Spontaneous Internal Biliary Fistula | Cleveland Clinic Journal of MedicineSpontaneous Internal Biliary Fistula | Cleveland Clinic Journal of Medicine

AbstractRECENTLY we had occasion to make the preoperative diagnosis of cholecystocolic fistula and demonstrate this complication of gallbladder disease at operation. The symptoms and roentgen findings were of sufficient diagnostic interest to stimulate this report.The patient had a history of multiple attacks of acute cholecystitis for many years and apparently developed the cholecystocolic fistula a few weeks before its recognition. The onset of fistula formation was characterized by a period of upper abdominal pain, fever, prostration, and diarrhea. Barium x-ray study of the colon was diagnostic for an internal biliary fistula.Case ReportA widow, aged 73, was admitted to the Clinic hospital with a presumptive diagnosis of subsiding acute cholecystitis. Twenty-three years previously a clinical diagnosis of chronic cholecystitis had been made because of a history of recurrent attacks of pain in the right upper abdomen radiating into the right scapular region, often accompanied by nausea and vomiting.
more infohttps://www.mdedge.com/ccjm/article/90008/spontaneous-internal-biliary-fistula

Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders - Full Text View - ClinicalTrials.govClinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders - Full Text View - ClinicalTrials.gov

Papillary cystadenoma of the epididymis or broad ligament. *Endolymphatic sac tumor. *Known or suspected cutaneous ... hereditary papillary renal cancer (HPRC), Birt Hogg Dube (BHD) and hereditary leiomyomatosis and renal cell acarcinoma (HLRCC) ... Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet ... specifically hereditary forms of Type II papillary renal cancer, clear cell renal carcinoma, renal oncocytoma, chromophobe ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT00001238

Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | HealthLink BCSalivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | HealthLink BC

... also known as malignant papillary cystadenoma, mucus-producing adenopapillary, or nonepidermoid, carcinoma; low-grade papillary ... Warthin tumor, also known as papillary cystadenoma lymphomatosum.. * Monomorphic adenomas:*Basal cell adenoma. (Refer to the ... Cystadenoma. (Refer to the cystadenocarcinoma section in the Cellular Classification of Salivary Gland Cancer section of this ... Cystadenocarcinoma is the malignant counterpart of cystadenoma.[3]. In a review that included 57 patients, the AFIP found that ...
more infohttps://www.healthlinkbc.ca/health-topics/ncicdr0000062920

1 - Forex trading account management1 - Forex trading account management

Papillary cystadenoma 9. 3193. A classic example of a dynamic pool model in action concerned the Arcto-Norwegian cod fishery, ...
more infohttp://oilforexprofits.com/forex-trading-account-management.html

Cuboid cell financial definition of cuboid cellCuboid cell financial definition of cuboid cell

Definition of cuboid cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is cuboid cell? Meaning of cuboid cell as a finance term. What does cuboid cell mean in finance?
more infohttps://financial-dictionary.thefreedictionary.com/cuboid+cell

Ductule | definition of ductule by Medical dictionaryDuctule | definition of ductule by Medical dictionary

Papillary cystadenoma of the epididymis. The intraepithelial neoplastic cells are morphologically and immunohistochemically of ...
more infohttps://medical-dictionary.thefreedictionary.com/ductule

PCE financial definition of PCEPCE financial definition of PCE

Papillary cystadenoma of the epididymis. A cubrir algunos de estos vacios vinieron a contribuir las Jornadas Academicas ...
more infohttp://financial-dictionary.thefreedictionary.com/PCE
  • The uniqueness of this pseudoendometrioid carcinoma lies in the fact that its mesonephric nature is revealed by the origin from a papillary cystadenoma of the broad ligament, where remnants of the mesonephric duct are seated, and the immunohistochemical profile, particularly a uniform negativity for estrogen and progesterone receptors, apical-luminal positivity for CD10, and strong nuclear positivity for GATA3. (ovid.com)