A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)
A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)
A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)
An adenocarcinoma in which the tumor elements are arranged as finger-like processes or as a solid spherical nodule projecting from an epithelial surface.
A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)
A multilocular tumor with mucin secreting epithelium. They are most often found in the ovary, but are also found in the pancreas, appendix, and rarely, retroperitoneal and in the urinary bladder. They are considered to have low-grade malignant potential.
Tumors or cancer of the APPENDIX.
A retention cyst of the salivary gland, lacrimal sac, paranasal sinuses, appendix, or gallbladder. (Stedman, 26th ed)
Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.
Distention of KIDNEY with the presence of PUS and suppurative destruction of the renal parenchyma. It is often associated with renal obstruction and can lead to total or nearly total loss of renal function.
A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. It is associated with previous pelvic radiation exposure in 20% of patients. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1702)
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.
A benign neoplasm of the ovary.
Tumors or cancer of the PAROTID GLAND.
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
A condition characterized by poorly-circumscribed gelatinous masses filled with malignant mucin-secreting cells. Forty-five percent of pseudomyxomas arise from the ovary, usually in a mucinous cystadenocarcinoma (CYSTADENOCARCINOMA, MUCINOUS), which has prognostic significance. Pseudomyxoma peritonei must be differentiated from mucinous spillage into the peritoneum by a benign mucocele of the appendix. (Segen, Dictionary of Modern Medicine, 1992)
Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.
Tumors or cancer of the BILE DUCTS.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Tumors or cancer of the SALIVARY GLANDS.
Surgical removal of the pancreas. (Dorland, 28th ed)
Organic compounds containing both the hydroxyl and carboxyl radicals.
The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.
Semidomesticated variety of European polecat much used for hunting RODENTS and/or RABBITS and as a laboratory animal. It is in the subfamily Mustelinae, family MUSTELIDAE.
Genus in the family FELIDAE comprised of small felines including the domestic cat, Felis catus (CATS) and its ancestor the wild cat, Felis silvestris.
MAMMARY GLANDS in the non-human MAMMALS.
An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues.
Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific. They are important molecular agents in the process of sperm maturation.
Carbohydrate antigen most commonly seen in tumors of the ovary and occasionally seen in breast, kidney, and gastrointestinal tract tumors and normal tissue. CA 125 is clearly tumor-associated but not tumor-specific.
Tumors or cancer of the UTERUS.
Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
Tumors or cancer of the PERITONEUM.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
Loss of structural differentiation and useful function of neoplastic cells.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Benign or malignant neoplasms of the FALLOPIAN TUBES. They are uncommon. If they develop, they may be located in the wall or within the lumen as a growth attached to the wall by a stalk.
A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
The study of the heart, its physiology, and its functions.
A medical specialty concerned with the diagnosis and treatment of SLEEP WAKE DISORDERS and their causes.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
The branch of medicine concerned with the evaluation and initial treatment of urgent and emergent medical problems, such as those caused by accidents, trauma, sudden illness, poisoning, or disasters. Emergency medical care can be provided at the hospital or at sites outside the medical facility.
A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).
Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.
Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.
INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.
Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
Extracts prepared from pancreatic tissue that may contain the pancreatic enzymes or other specific uncharacterized factors or proteins with specific activities. PANCREATIN is a specific extract containing digestive enzymes and used to treat pancreatic insufficiency.
A preparation of hog pancreatic enzymes standardized for lipase content.
Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.

Adenovirus-mediated expression of p53 or p21 in a papillary serous endometrial carcinoma cell line (SPEC-2) results in both growth inhibition and apoptotic cell death: potential application of gene therapy to endometrial cancer. (1/83)

Papillary serous endometrial carcinoma is an aggressive tumor characterized by late-stage presentation, i.p. spread, and poor prognosis. It is histologically similar to serous papillary carcinoma of the ovary. Preclinical studies have shown that adenovirus-mediated expression of p53 in ovarian cancer cell lines causes growth inhibition and apoptosis in vitro and in vivo. Such studies provide the rationale for Phase I Adp53 gene therapy clinical trials in ovarian cancer. In the present study, we compared the efficacy of adenoviral vectors containing p53 (Adp53) or p21 (Adp21) in a papillary serous endometrial tumor cell line (SPEC-2) that contains mutated p53. Growth assays revealed that both Adp53 and Adp21 were efficacious in decreasing cell proliferation as assessed by anchorage-dependent and anchorage-independent growth assays. However, as compared with Adp53, the effects of Adp21 tended to be more transient and less marked. Strikingly, Adp21, but not Adp53, induced a G1 arrest in SPEC-2 endometrial adenocarcinoma cells. In contrast, as assessed by induction of hypodiploid peaks, free DNA ends detected by a terminal deoxynucleotidyl transferase-based assay, and annexin V positivity, p53 was more effective than p21 in inducing cell death by apoptosis. Compatible with the more efficient induction of apoptosis, Adp53, but not Adp21, induced a marked increase in expression of the preapoptotic molecule BAX without a concomitant change in expression of the antiapoptotic mediator Bcl-2. The differential effects of Adp53 and Adp21 on cell cycle progression and apoptosis may be related to the reversibility of p21-induced cell cycle arrest and the irreversibility of p53-induced apoptosis. Thus, at least in the papillary serous endometrial carcinoma cell line SPEC-2, Adp53 may be more effective than Adp21 as a gene therapeutic. Nevertheless, these preclinical studies suggest that papillary serous endometrial carcinoma is a potential target for p53- or p21-mediated gene therapy.  (+info)

Immunohistochemical profile of endometrial adenocarcinoma: a study of 61 cases and review of the literature. (2/83)

The differences in immunohistochemical expression of p53, bcl-2, bax, estrogen receptor (ER), and progesterone receptor (PR) were evaluated in 40 endometrioid and 21 papillary serous carcinomas of endometrium and correlated with known predictors of survival, such as grade and stage. Uterine papillary serous adenocarcinomas (UPSA) showed significantly higher p53 expression than did uterine endometrioid adenocarcinomas (UEA) (76.2% versus 35%), whereas both ER and PR were more often positive in endometrioid than in serous tumors (p = .005 and .0005). No significant difference was found in bcl-2 and bax expression between both histologic types. However, there was definite decrease in intensity of bcl-2 in UPSA compared with UEA. In endometrioid carcinoma, p53 overexpression was associated with high-grade and advanced-stage tumors (p = .0006 and .006), whereas ER and PR expression was associated with low-grade and early-stage tumors (p = .0006 and .0001; p = .003 and .0006). Bcl-2 immunopositivity was more common in low-grade, early-stage rather than in high-grade, advanced-stage adenocarcinomas, but the difference was not statistically significant (p = .24 and .07). Bax immunopositivity was associated with well-differentiated (p = .04) and early-stage tumors. Furthermore, a significant inverse relationship between bax and p53 reactivity was defined (p = .05), especially in tumors of endometrioid type. Bax and PR immunoexpression correlated near the limit of statistical significance (p = .08), whereas no relationship was found among bax, bcl-2, and ER immunopositivity. Our results indicate that the differences in immunohistochemical profiles of endometrioid and serous carcinomas support the existence of different molecular pathways of their development. The correlation of immunohistochemical findings with histologic grade and clinical stage could help in predicting biologic behavior and planning treatment in patients who are diagnosed as having these tumors.  (+info)

Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer. (3/83)

INTRODUCTION: Patients with recurrent ovarian cancer were treated with a replication-deficient recombinant adenovirus containing the herpes simplex virus thymidine kinase gene administered intraperitoneally (i.p.) followed by administration of an anti-herpetic prodrug and topotecan. MATERIALS AND METHODS: A total of 10 patients with stage IIIc epithelial ovarian cancer underwent secondary debulking to < or =0.5 cm residual tumor. Patients with normal i.p. flow received i.p. delivery of adenovirus. Two patients each were treated on dose level 1 (2 x 10(10) vector particles (VP)), dose level 2 (2 x 10(11) VP), and dose level 3 (2 x 10(12) VP); four patients were treated on dose level 4 (2 x 10(13) VP). Acyclovir and topotecan were started 24 hours after vector delivery. RESULTS: No patient treated at any dose level incurred unanticipated toxic effects, and all side effects resolved. The most common adverse event was myelosuppression: grade 3 or 4 thrombocytopenia with grade 2-4 anemia in three patients and grade 3 or 4 neutropenia in eight patients. Three patients developed thrombocytosis and three patients had a mild elevation of serum glutamic pyruvic transaminase/alanine aminotransferase. Temperature elevations that were not associated with detectable infection occurred in two patients. DISCUSSION: I.p. delivery of adenoviral vector with concomitant topotecan chemotherapy was well tolerated without significant lasting toxicities. Side effects were independent of the dose of adenoviral vector.  (+info)

Distinct allelic loss patterns in papillary serous carcinoma of the peritoneum. (4/83)

Tumor and normal tissues from 55 patients with papillary serous carcinoma of the peritoneum (PSCP) were analyzed. Polymerase chain reaction amplification of tandem repeat polymorphism was used to screen for loss of heterozygosity (LOH). We mapped 22 oligonucleotide primers to chromosomes 1p, 3p, 6q, 7q, 9p, 11p, 17p, 17q, and Xq. Germline BRCA1 mutation status of 43 patients was determined previously. High frequencies (> 30%) of LOH in PSCP were observed on 6q, 9p, 17p, 17q, and Xq. Compared with allelic loss of serous epithelial ovarian carcinoma (SEOC), the frequency of LOH was significantly lower in PSCP on 1p, 7q, 11p, 17p, and 17q. Of 43 cases screened for germline BRCA1 mutations, 9 cases were identified with mutations. The frequencies of LOH were not significantly different among the BRCA1-related and BRCA1-unrelated PSCP cases. The high LOH rate identified on 6q, 9p, 17p, 17q, and Xq in PSCP suggests that candidate tumor suppressor genes residing in these regions may be important for the development of the tumor. Compared with allelic loss of SEOC, PSCP exhibits a significantly lower frequency of LOH on chromosomes 1p36, 7q31.3, 11p15.1, 17p13.1, and 17q21. An increase in susceptibility to the acquisition of allelic loss in BRCA1-related PSCP cannot be identified.  (+info)

Growth regulation of ovarian cancer cell line HO-8910 by transforming growth factor beta 1 in vitro. (5/83)

OBJECTIVE: To further understand the role of growth regulation of human ovarian cancer cells by transforming growth factor (TGF) beta 1. METHODS: The cell proliferation, cAMP synthesis, gene expression, and induction of programmed cell death (PCD) in human epithelial ovarian cancer cell line HO-8910 cells exposed to TGF beta 1 in vitro were studied. RESULTS: TGF beta 1 inhibited cell growth and DNA synthesis, and induced G0/G1 arrest in cell cycle. It could also trigger PCD in cells. This induction of PCD may occur within G0/G1 phase. Meanwhile, the assay also showed that TGF beta 1 could inhibit the mRNA expression of c-myc, EGFR and TGF beta 1 genes in cells. CONCLUSIONS: TGF beta 1 can not only act as an autocrine to inhibit cell proliferation, but also trigger PCD in HO-8910 cells. These functions may be fulfilled through some specific signal transduction pathways.  (+info)

Oncocytic biliary cystadenocarcinoma is a form of intraductal oncocytic papillary neoplasm of the liver. (6/83)

Biliary cystadenocarcinoma with oncocytic differentiation was first reported in 1992. This is a report of a second case. The patient (a 71-year-old man) was admitted to our hospital complaining of abdominal fullness. Multicystic lesions were identified in the left hepatic lobe radiologically. The patient died of peritoneal dissemination of carcinoma 20 months later. At autopsy, the tumor of the left hepatic lobe was found to be composed of adjoining multiple cystic lesions and a solid lesion with infiltration of the hepatic hilus and peritoneal dissemination. Histologically, the multicystic lesions were covered by papillary neoplastic epithelial cells with an eosinophilic granular cytoplasm resembling that of oncocytes and a fine fibrovascular core. The cyst wall was fibrous, but there was no mesenchymal stroma. In the solid lesion and infiltrated areas, acidophilic and granular carcinoma cells formed small glandular or solid cord patterns with much mucin secretion (mucinous carcinoma). Immunohistochemically, carcinoma cells of both components were found to contain many mitochondria and showed the phenotypes of hepatocytes and cholangiocytes. Interestingly, the intrahepatic biliary tree also was invaded by carcinoma cells. This may be a case of intraductal oncocytic papillary neoplasm of the left hepatic lobe followed by secondary cystic dilatation of the affected bile duct.  (+info)

Comparison of 'pattern recognition' and logistic regression models for discrimination between benign and malignant pelvic masses: a prospective cross validation. (7/83)

OBJECTIVES: To test prospectively the diagnostic performance of two logistic regression models for calculation of individual risk of malignancy in adnexal tumors (the 'Tailor model' and the 'Timmerman model'), and to compare them to that of 'pattern recognition' (subjective evaluation of the gray-scale ultrasound image and color Doppler ultrasound examination). DESIGN: Consecutive women with a pelvic mass judged clinically to be of adnexal origin underwent preoperative ultrasound examination including color and spectral Doppler examination. The same examination techniques and definitions as those used in the studies in which the logistic regression models had been created were used. The Tailor model was tested in 133 women (35 of whom hada malignancy) and the Timmerman model in 82 women (29 of whom had a malignancy). A subset of 79 women (28 of whom had a malignancy) was used to compare the performance of the Tailor model and the Timmerman model by calculating and comparing the areas under the receiver operating characteristics curves of the two models. Sensitivity and specificity with regard to malignancy were calculated for all three methods. RESULTS: Pattern recognition performed better than the two logistic regression models (sensitivity around 85%, specificity around 90%). Using a risk of malignancy of > 50% to indicate malignancy (as suggested in the original publications), the sensitivity of the Tailor model was 69% and the specificity 88% (n = 133). The corresponding values for the Timmerman model were 62% and 79% (n = 82). The receiver operating characteristics curves showed the two logistic regression models to have similar diagnostic properties (area under the curve, 0.87 vs. 0.84; P = 0.25; n = 79). The diagnostic performance of the mathematical models was much poorer in this study than in those in which the models had been created. CONCLUSION: The poor diagnostic performance of the mathematical models can probably be explained by subtle differences in definitions and examination technique and by differences between the original tumor populations and the study population. For mathematical models to be generally useful, they probably need to be created on the basis of a very large number of tumors, and the variables in the model must be unequivocally defined and the examination technique meticulously standardized.  (+info)

WT1 immunoreactivity in uterine papillary serous carcinomas is different from ovarian serous carcinomas. (8/83)

WT1 diffusely stains most ovarian serous carcinomas; reactivity of uterine papillary serous carcinomas has not been evaluated. We studied WT1 expression in 13 International Federation of Gynecology and Obstetrics stage 1 and 5 stage 3 or 4 uterine papillary serous carcinomas without ovarian metastases and compared their reactivity with the WT1 staining of 30 ovarian serous carcinomas. WT1 reactivity was evaluated with the C19 and 6F-H2 antibody clones. All 18 uterine papillary serous carcinomas were nonreactive for WT1. The nonovarian metastases of the 5 high-stage uterine papillary serous carcinomas also were nonreactive for WT1. In contrast, 29 (97%) of 30 ovarian serous carcinomas were reactive for WT1. WT1 reactivity in an unknown primary serous carcinoma would suggest it is from a nonuterine site. The mechanisms underlying these findings are unknown. They raise the possibility of genetic differences between the 2 morphologically similar neoplasms.  (+info)

Uterine papillary serous carcinoma (UPSC) is an uncommon, but aggressive variant of endometrial carcinoma that has a high recurrence rate and poor response to therapy. It has a propensity to metastasize throughout the abdomen, similar to serous carcinoma of the ovary. In fact, many patients with disease apparently confined to the uterus have microscopic intra-abdominal spread at the time of diagnosis. Recurrences are common both in the pelvis as well as in the upper abdomen.. After staging and debulking of gross disease, adjuvant radiation therapy is recommended to treat patients with endometrial carcinoma at high risk for recurrent disease. High-risk features include histologic cell type, grade, depth of myometrial invasion, cervical extension, lymph-vascular invasion, adnexal involvement, intraperitoneal spread, positive peritoneal cytology, and positive lymph nodes. Pelvic radiation can limit local recurrences to less than 6.5%. However, approximately 25-30% of patients with high-risk ...
Objectives: To determine recurrence patterns and survival outcomes of stage II uterine papillary serous carcinoma (UPSC) patients treated by various modalities with an emphasis on carboplatin/paclitaxel-based chemotherapy (CT) +/- radiotherapy (RT). Methods: A retrospective, multi-institution study of women with stage II UPSC diagnosed from 1992 to 2006 was performed. All patients underwent comprehensive surgical staging. Treatment included observation (OBS), RT (vaginal brachytherapy, whole pelvic and/or whole abdominal therapy), or ≥ 3 cycles carboplatin/paclitaxel alone or with RT. Recurrence and survival outcomes were determined. Results: We identified 55 subjects: 10 treated with OBS, 26 with RT alone and 19 with CT +/- RT. After a median follow-up of 33 mos (range, 10-119), 20 recurrences (36%) were observed. There was an overall difference in recurrence based upon treatment (p = .013). Specifically, all CT +/- RT treated patients had a lower risk of recurrence (11%) compared to patients ...
Uterine papillary serous carcinoma: A rare type of endometrial carcinoma with worse outcomes-IJOGR-Print ISSN No:-2394-2746 Online ISSN No:-2394-2754Article DOI No:-10.18231/2394-2754.2019.0022,Indian Journal of Obstetrics and Gynecology Research-IP Innovative Publication Pvt Limited, Medical Journals Publication, Op
A simple, papillary cystic adenocarcinoma of the mammary gland with metastases to the internal iliac and mesenteric lymph nodes, liver, and spleen was observed in a 12 to 13 year old female black-footed ferret (Mustela nigripes). Histologically, the tumor was aggressive, and lymphatic invasion was found. Attempts at virus isolation were negative. Other findings were bilateral infarcts in the kidneys, apparently resulting in acute renal shutdown and death, multiple thrombi in the right atrium, aortic arteriosclerosis, and focal interstitial pneumonia....
Researchers used Caris Molecular Intelligence® to evaluate 240 uterine papillary serous carcinoma (UPSC) and 1,587 epithelial ovarian serous carcinoma (EOC-S) samples, and to compare the molecular profiles of the two cancer subtypes.. The tumor suppressor gene TP53 was the most commonly mutated gene in both UPSC and EOC-S (76% vs. 69%) samples. UPSCs were more likely than EOC-S samples to harbor mutations in the oncogenes PIK3CA (29% vs. 2%), FBXW7 (12% vs. 1%), KRAS (9% vs. 5%), the tumor suppressor protein PTEN (7% vs. 1%), and CTNNB1 (2% vs. 0%).. Whereas uterine papillary serous carcinoma appears to have a distinct mutation profile, indicating higher activity of the PI3K/PTEN/mTOR pathway, we saw no differences between uterine papillary and ovarian serous carcinomas in alteration of the homologous recombination pathway, remarked principal investigator Robert DeBernardo, MD, Gynecologic Oncologist and Director of Minimally Invasive Surgery at the Cleveland Clinic Ob/Gyn & Womens Health ...
I guess my hamster days steroid high is over, because I slept 10 hours last night and woke up with something similar to what Marge described, a sort of fogginess. Its not bad, but I feel like if I crawled back under the covers, I just might go back to sleep again. (Not doing that!) I agree that we are all doing so much better than any of us probably dared to hope. There are surely some rough days ahead, but one day at a time is the way to go, and making the most of each good day. I wonder if we will continue to come here after our treatments are over??? I see 20-year survivors posting here on other boards, wanting to be here as a resource to those that come after them with their same cancers. Id like to think well be like that, with this thread always flagged for email alerts, ready to jump back in when those newly diagnosed with UPSC using the SEARCH box, find this thread. Even if any of us decide to close the door on this chapter of our life and never look back, think how great it will ...
Zanotti The Cleveland Clinic Foundation Uterine papillary serous carcinoma (UPSC) is undoubtedly an intense malignancy which has a histologic visual appeal and pattern of spread that resembles that of papillary serous adenocarcinoma with the ovary. The current conventional therapy for Superior ovarian most cancers, cisplatin or carboplatin moreover paclitaxel, results in high aim response premiums for that tumor. This program has Up to now not been evaluated in i thought about this UPSC. Approaches: 20-four sufferers with UPSC treated with platinum-based mostly chemotherapy and paclitaxel were being retrospectively evaluated. Eighteen clients acquired these agents within the adjuvant placing (n = 9) or for sickness persistent just after initial surgical management (n = nine). Eleven patients gained one or more classes of this drug blend for recurrent ailment, 5 of whom experienced prior publicity while in the First setting ...
Ueda SM, Yap, KL, Davidson, B et al. Expression of fatty acid synthase depends on NAC1 and is associated with recurrent ovarian serous carcinomas. J Oncology 2010;2010:285191.. Krill LS, Ueda SM, Gerardi M, Bristow RE. Analysis of postoperative complications associated with the use of anti-adhesion sodium hyaluronate-carboxymethylcellulose (HA-CMC) barrier after cytoreductive surgery for ovarian, fallopian tube and peritoneal cancers. Article in press for Gynecol Oncol. 2011 Feb; 120(2):220-3. Skaznik-Wikiel ME, Ueda SM, Frasure HE, Rose PG, Fleury A, Grumbine FC, Nickles-Fader A. Abnormal cervical cytology in the diagnosis of uterine papillary serous carcinoma: earlier detection of a poor prognostic cancer subtype? Acta Cytol 2001;55(3):255-60.. Bristow RE, Ueda S, Gerardi MA, Ajiboye OB, Ibeanu OA. Analysis of racial disparities in stage IIIC epithelial ovarian cancer care and outcomes in a tertiary gynecologic oncology referral center. Gynecol Oncol 2011;122(2):319-23.. Giuntoli RL, Gerardi ...
PRIMARY OBJECTIVES:. I. To determine if treatment with cisplatin and volume-directed radiation followed by carboplatin and paclitaxel for 4 cycles (experimental arm) reduces the rate of recurrence or death (i.e., increases recurrence-free survival) when compared to chemotherapy consisting of carboplatin and paclitaxel for 6 cycles (control arm) in patients with stages III-IVA endometrial carcinoma (, 2 cm residual disease) or patients with International Federation of Gynecology and Obstetrics (FIGO) 2009 stage I or II serous (uterine papillary serous carcinoma [UPSC]) or clear cell endometrial carcinoma and positive cytology.. SECONDARY OBJECTIVES:. I. To determine if treatment with cisplatin and volume-directed radiation followed by carboplatin and paclitaxel for 4 cycles (experimental arm) reduces the rate of death (i.e., increases survival) when compared to chemotherapy consisting of carboplatin and paclitaxel for 6 cycles (control arm) in patients with stages III-IVA endometrial carcinoma (, ...
Decreased Expression of 14-3-3,i,σ,/i, Is Predictive of Poor Prognosis for Patients with Human Uterine Papillary Serous Carcinoma (2013 ...
Pancreatic cancer remains a leading cause of death despite its relatively low incidence. As in many other solid tumors, angiogenesis is critical to the growth and metastasis of this cancer. Through serial in vivo passages in mice, we have developed a highly aggressive variant of human pancreatic cancer cell line XPA-1 which shows more rapid primary tumor growth, faster time to metastasis, and more rapid lethality than the parental cell line. The high-metastatic variant developed a much denser tumor vasculature early during growth within the pancreas. Interestingly, examination of the in vitro growth of this aggressive variant yielded no significant difference from the parental cell line. Real-time PCR evaluation of genes involved in angiogenesis revealed a 24-fold increase in Thrombospondin-1 expression in cells derived from the high-metastatic variant when compared with the parental cell line. These findings provide direct evidence that elevated capability for angiogenesis, mediated by specific ...
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Patricia, Ill try to answer the best I can. According to the NCCN Guidelines (which my GYN/ONC group uses), after surgical debulking adjuvant treatment is decided by the patients STAGE. Chemo is a primary treatment for UPSC - papillary serous carcinoma. I didnt question whether to have this or not. EVERYTHING has side effects and I guess we just weigh the pros and cons. My head spins just reading the inserts for prescriptions. I also had fatigue and some neurapathy. I still have some in my toes after 5 months but it is getting better with time.. Radiation is another adjuvant treatment and there are side effects with this. I have stage 3a UPSC and my doctor in so many words thinks the benefits do not outweigh the risks FOR ME. He thinks that I have very good odds NOT to have a recurrence and if I do have one in the vaginal cuff he said he has a 90% cure rate for this. He is very well respected in the field so I am going with his thinking. I think we all need to make these decisions with the ...
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of the uterus, adenexae, onsectonomy and appendectomy for papillary serous carcinoma of the ovary . After 6 chemotherapy cycles tumor recurrence .... ...
The UPSC Civil Services Examinations are considered as one of the prestigious & toughest examinations in the country. It needs a lot of strategic preparation & smart work to crack this exam. In all these preparation strategies, revision is considered as the key to success.. However, It is not advisable to read so many books sources, but important is to refer only to fewer sources and compiled study notes & to revise it multiple times.. Revision makes you confidant to excel in the exams. Revision is just like going with the same route again & again and your mind will remember everything on its way automatically. We will discuss some scientifically proven techniques used all over the world to do the most important thing of any learning process i.e. REVISION.. ...
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TY - JOUR. T1 - p53 Overexpression and bcl-2 persistence in endometrial carcinoma. T2 - Comparison of papillary serous and endometrioid subtypes. AU - Zheng, Wenxin -. AU - Cao, Peiqin. AU - Zheng, Mei. AU - Kramer, Elmer E.. AU - Godwin, Thomas A.. PY - 1996/5. Y1 - 1996/5. N2 - Forty-two cases, including 21 uterine papillary serous carcinomas (UPSC) and 21 age-, nuclear-grade-, and clinical-stage-matched uterine endometrioid carcinomas (UEC), were studied immunohistochemically for p53 and bcl-2 in archival paraffin-embedded tissue. Compared to UEC (28.6% positive), UPSC (71.4% positive) had a significantly higher frequency of p53 overexpression (P = 0.005); furthermore, in a clinical-stage-matched fashion, a higher frequency of p53 overexpression was found in early-stage cases (P = 0.032), but not in late-stage cases. In a nuclear-grade-matched comparison, no statistical difference in p53 overexpression was identified between the two subtypes, although UPSC had stronger p53 immunoreactivity ...
Serous adenocarcinoma is a type of epithelial ovarian cancer, which is the most common among ovarian cancers. Ovarian cancers account for 6 percent of all cancers among women according to the American Cancer Society. The five-year survival rate in women with advanced ovarian cancer is 15 to 20 percent, but if the disease is found at an early stage, survival approaches 90 percent [16]. Women with a personal/family history of ovarian or other cancers are at the highest risk of having ovarian serous carcinoma, especially if their mother or sister had ovarian cancer. Other risk factors include: increased age, use of high-dose estrogens without progesterone for a long period, uninterrupted ovulation due to infertility, no pregnancies, no use of birth control, and defects in the BRCA1 or BRCA2 genes. Unfortunately, in most women ovarian serous carcinoma is not diagnosed until the disease is advanced, and has spread into the abdomen or beyond due to non-clear physical symptoms. Therefore, early ...
The TP53 gene mutation frequency in ovarian serous carcinomas has been reported to range between 50% and 80%. A research team working at the The Sidney Kimmel Comprehensive Cancer Center of The Johns Hopkins Medical Institutions (Johns Hopkins) made several important findings regarding TP53 gene mutations with respect to high grade ovarian serous carcinoma, as reported in the International Journal of Gynecological Cancer. Ovarian serous carcinoma is the most common tumor subtype within the epithelial ovarian cancer histological classification.. According to the Johns Hopkins research team, a stringent analysis of the TP53 gene using purified epithelial tumor samples has not been performed to accurately assess the TP53 gene mutation frequency and its correlation to tumor histologic grade. The research team assessed the TP53 gene mutational profile in a relatively large series of high-grade (53 primary tumors and 18 recurrent tumors) and 13 low-grade ovarian serous tumors. All samples were ...
Uterine serous carcinoma is a rare and highly aggressive variant of endometrial cancer. Uterine serous carcinoma accounts for 10% of all endometrial cancer; however, it carries the poorest prognosis, with 5-year survival rates as low as 55%. Whole-exome sequencing studies have recently reported c-Myc gene amplification in a large ...
Papillary Adenocarcinoma is a type of sinonasal cancer that is found in the wood working industry due to the exposure to of wood dust.
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4. Candidates are not permitted to use calculators for answering objective type papers.. Note: Compensatory time of twenty minutes per hour shall be permitted for the candidates with locomotors disability and cerebral palsy where dominant (Writing) extremity is affected to the extent of slowing the performance of function (minimum of 40% impairment) in the Combined Medical Services Examination, 2016.. Part II: Personality Test: Candidates who qualify in the Computer based Examination will be called for Interview/ Personality Test to be conducted by the Union Public Service Commission (UPSC). The Interview/ Personality Test will cary 100 marks ...
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GENERAL SCIENCE FOR SSC AND UPSC. Candidates preparing for GENERAL SCIENCE FOR SSC AND UPSC ,SSC Graduate Level, CPO SI, Uttarakhand SI, Railway, UPSC, PCS exams and other state level competitive exams must go through the important General Science questions already asked in the exams as there is a huge probability of repetition of such questions again and again in the upcoming competitive exams. So its always advisable to keep brushing your GK besides gaining the new found one!. For your convenience we have come up with the series of collection of important General Science GK questions which can be asked in the upcoming Staff selection Commission SSC exams and other competitive exams. Just go through these questions and remain tension free…. GENERAL SCIENCE FOR SSC AND UPSC. Q 1- Permanent hardness of water may be removed by the addition of:. ...
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Rare and highly aggressive, a rhabdoid tumour is generally found in the cerebellum and occurs in children aged two to 13.. Initially considered an aggressive variant of Wilms tumour of the kidney, its now believed to be a subset of medulloblastomas.. ...
Combined Defence Services Examination(CDSE) is conducted by Union public Service commission (UPSC) . UPSC conducts two exam yearly. The CDS I exam will be held in the month of February and the CDS II will be held in AUG. CDSE exam consist of three parts namely General knowledge, English and Elementary mathematics. The questions are all objective type question and each paper will be give 2 hour for the exam. There is negative marking in this exam. Through this exam on can join the three armed forces (Army, Navy and Air-force). Two entry is possible with CDSE - IMA and OTA. For IMA one has write all the 3 papers , whereas for OTA only GK and English paper is enough ...
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9. The value of all final goods and services produced by the normal residents of a country arid their property, whether operating within the domestic territory of the country or outside in a year is termed as ...
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From today onward, we will start providing you the daily GA Questions from this portal only. This will help you build a strong base for the current affairs. These questions are picked from the various news that has been posted on this platform. So keep practicing the questions and the answers to this question will be provided tomorrow morning. ...
Reading Time: 2 mins The government is thinking of a plan to sell LPG blended with methanol, which could facilitate reduction in its cooking gas subsidy by 1/3rd of its current prices. The plan is to manufacture methanol from abundantly available low-quality coal and other bio resources, and also produce it synthetically. The project would be implemented by the NITI Aayog. ...
Members - Page 31/34 - Université Sorbonne Paris Cité (USPC) -...: Le pôle Sciences exactes et Technologie (SET) de lUniversité Sorbonne Paris Cité (USPC) est
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Question Bank contains selective questions from papers of previous year competitive exams conducted by Staff Selection Commission (SSC), Union Public Service Commission (UPSC) and other States Public Service Commissions (UPPSC)(WBPSC) etc.. ...
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... cystadenocarcinoma, mucinous MeSH C04.557.470.200.025.480.230 - cystadenocarcinoma, papillary MeSH C04.557.470.200.025.480.240 ... cystadenocarcinoma, papillary MeSH C04.557.470.590.480.240 - cystadenocarcinoma, serous MeSH C04.557.470.590.485 - cystadenoma ... papillary MeSH C04.557.470.200.025.085.225 - carcinoma, papillary, follicular MeSH C04.557.470.200.025.095 - adenocarcinoma, ... cystadenocarcinoma MeSH C04.557.470.590.480.225 - cystadenocarcinoma, mucinous MeSH C04.557.470.590.480.230 - ...
Two tumor types were explored during the pilot phase, Glioblastoma Multiforma (GBM) and Cystadenocarcinoma of the Ovary. The ... TCGA Targeted Tumors: lung squamous cell carcinoma, kidney papillary carcinoma, clear cell kidney carcinoma, breast ductal ... ovarian serous cystadenocarcinoma, lung squamous cell carcinoma, adrenocortical carcinoma, Diffuse Large B-cell lymphoma, ... "Integrated Genomic Characterization of Papillary Thyroid Carcinoma". Cell. 159 (3): 676-690. doi:10.1016/j.cell.2014.09.050. ...
Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... Papillary serous cystadenocarcinomas may exhibit psammoma bodies upon histopathology. Papillary serous cystadenoma Kosary, ... Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian ...
Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... Papillary thyroid carcinoma Papillary renal cell carcinoma Micropapillary subtype of lung adenocarcinoma Ovarian papillary ... serous cystadenoma and cystadenocarcinoma Endometrial adenocarcinomas (Papillary serous carcinoma ~3%-4%) Meningiomas, in the ... The term is derived from the Greek word ψάμμος (psámmos), meaning "sand". Psammoma bodies are associated with the papillary ( ...
... kidney papillary carcinoma, clear cell kidney carcinoma, breast ductal carcinoma, renal cell carcinoma, cervical cancer ( ... ovarian serous cystadenocarcinoma, lung squamous cell carcinoma, adrenocortical carcinoma, Diffuse Large B-cell lymphoma, ... Serous cystadenocarcinoma Canada: Pancreatic Cancer - Ductal adenocarcinoma and Prostate Cancer - Adenocarcinoma China: Gastric ...
Papillary serous cystadenocarcinoma "Female Genital Pathology". Retrieved 2009-03-23. King JC, Ng TT, White SC, Cortina G, ... Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from glandular epithelium, in which ... Reber HA, Hines OJ (October 2009). "Pancreatic serous cystadenocarcinoma: a case report and review of the literature". J ...
Cystadenocarcinoma *Papillary serous cystadenocarcinoma. *Krukenberg tumor. *Endometrioid tumor. *Clear-cell ovarian carcinoma ...
Cystadenocarcinoma *Papillary serous cystadenocarcinoma. *Krukenberg tumor. *Endometrioid tumor. *Clear-cell ovarian carcinoma ...
Cystadenocarcinoma *Papillary serous cystadenocarcinoma. *Krukenberg tumor. *Endometrioid tumor. *Clear-cell ovarian carcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma. ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma. ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ... Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing ... The cystic spaces have epithelium referred to as papillary infoldings that protrude into them. Additionally, the epithelium has ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma ...
Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... Papillary adenocarcinoma. *Giant-cell carcinoma. Small-cell carcinoma. *Combined small-cell carcinoma ...
Several studies have shown that EGFR-TKI's are particularly active in papillary and non-mucinous bronchioloalveolar carcinoma ... Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... EGFR-targeted agents appear particularly effective in papillary adenocarcinoma,[27][28] non-mucinous bronchioloalveolar ... modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and ...
Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... Papillary adenocarcinoma. *Giant-cell carcinoma. Small-cell carcinoma. *Combined small-cell carcinoma ...
Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... Papillary adenocarcinoma. *Giant-cell carcinoma. Small-cell carcinoma. *Combined small-cell carcinoma ...
粘液性囊腺瘤 / Mucinous cystadenocarcinoma(英语:Mucinous cystadenocarcinoma) *Pseudomyxoma peritonei(英语:Pseudomyxoma peritonei) ... 胰腺导管内乳头状黏液肿瘤(英语:Intraductal papillary mucinous neoplasm) ... 卵巢浆液性囊腺瘤 / Pancreatic serous cystadenoma(英语:
... papillary cystic adenocarcinoma of the mammary gland with metastases to the internal iliac and mesenteric lymph nodes, liver, ... Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. Journal of Wildlife Diseases By:. J.W. ... Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. Series title:. Journal of Wildlife ... A simple, papillary cystic adenocarcinoma of the mammary gland with metastases to the internal iliac and mesenteric lymph nodes ...
Cystadenocarcinoma, Serous. Cystadenocarcinoma. Carcinoma. Uterine Neoplasms. Neoplasms, Glandular and Epithelial. Neoplasms by ... A Study of Radiation Therapy and Paclitaxel and Carboplatin in Patients With Uterine Papillary Serous Carcinoma. The safety and ... Uterine papillary serous carcinoma (UPSC) is an uncommon, but aggressive variant of endometrial carcinoma that has a high ... A Pilot Phase II Trial of Radiation Therapy Sandwiched Between Paclitaxel and Carboplatin in Patients With Uterine Papillary ...
Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer ... Papillary serous cystadenocarcinomas may exhibit psammoma bodies upon histopathology. Papillary serous cystadenoma Kosary, ... Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian ...
Familial risks of over 4.0 were found for serous papillary cystadenocarcinoma of the ovary, papillary thyroid cancer and low- ... Cystadenocarcinoma (papillary cystadenocarcinoma) of the salivary gland is a rare malignant neoplasm... ... Cystadenocarcinoma (papillary cystadenocarcinoma) of the submandibular gland. A Harimaya. Department of Otolaryngology, Sapporo ... Cystadenocarcinoma (papillary cystadenocarcinoma) of the submandibular gland. A Harimaya. Department of Otolaryngology, Sapporo ...
Cytomorphologic features of papillary cystadenocarcinoma of the parotid. , Diagnostic cytopathology , 6/1/2002 ... Cytomorphologic features of papillary cystadenocarcinoma of the parotid. Kusum Kapila Kusum Verma 6/1/2002 ... Kapila K, Verma K. Cytomorphologic features of papillary cystadenocarcinoma of the parotid. Diagn Cytopathol. 2002;26(6):392-7. ... Papillary cystadenocarcinomas of the parotid are rare but can be accurately diagnosed on FNAC. However, they need to be ...
Serous papillary cystadenocarcinoma of the ovary. Last updated on May 10, 2019 at 16:47 ... This cyst is lined by atypical epithelial cells, and it contains papillary processes. ...
... was diagnosed as papillary mucinous papillary mucinous cystadenocarcinoma. Nonetheless, the cellular atypia found was ... In most cases, papillary cystadenocarcinoma is asymptomatic and has slow growth10-11. The concerned clinical case was a ... Papillary mucinous cystadenocarcinoma can be histologically described by the presence of large cystic spaces filled with mucus ... Papillary cystadenoma and cystadenocarcinoma of salivary glands; two unusual entities. Med Oral Patol Oral Cir Bucal. 2008;13(7 ...
MARIANO, Ronaldo Célio et al. Papillary mucinous cystadenocarcinoma: rare malignant tumor in minor salivary gland. RGO, Rev. ... was diagnosed as papillary mucinous papillary mucinous cystadenocarcinoma. Nonetheless, the cellular atypia found was ... Clinical case description of a papillary mucinous cystadenocarcinoma, extremely rare malignant tumor in the salivary gland and ...
Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of high-grade ... Khaki, F., Javanbakht, J., Sharifzad, S. et al. Retraction note: Metastatic ovarian papillary cystadenocarcinoma to the small ... Retraction note: Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of ... Ovarian papillary cystadenocarcinomas in a green iguana (Iguana iguana). J Comp Pathol. 2004;130(2-3):223-8. ...
... resources and questions answered by our Genetic and Rare Diseases Information Specialists for Papillary cystadenocarcinoma ... PubMed is a searchable database of medical literature and lists journal articles that discuss Papillary cystadenocarcinoma. ...
Papillary serous cystadenocarcinoma "Female Genital Pathology". Retrieved 2009-03-23. King JC, Ng TT, White SC, Cortina G, ... Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from glandular epithelium, in which ... Reber HA, Hines OJ (October 2009). "Pancreatic serous cystadenocarcinoma: a case report and review of the literature". J ...
... papillary serous cystadenocarcinoma was found to be associated with ovarian and skin malignancies and with myeloma; and ... risk of developing endometrioid carcinoma was slightly greater than the risk of developing papillary serous cystadenocarcinoma. ...
Cystadenocarcinoma, Serous. Adenocarcinoma, Papillary. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. ... Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, ... PHASE II: Participants must have histologically or cytologically grade 2 or 3 (high-grade) papillary-serous or endometrioid ... Ovarian Serous Surface Papillary Adenocarcinoma Progesterone Receptor Negative Recurrent Breast Carcinoma Recurrent Fallopian ...
... kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous ... cell carcinoma; MESO, mesothelioma; OV, ovarian serous cystadenocarcinoma; PAAD, pancreatic adenocarcinoma; PCPG, ...
... kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; OV, ovarian serous ... cystadenocarcinoma; PAAD, pancreatic adenocarcinoma; PRAD, prostate adenocarcinoma; SARC, sarcoma; STAD, stomach adenocarcinoma ...
In the present study, a case of isolated small intestine metastasis of ovarian papillary cystadenocarcinoma was reported. A 7- ... this is the first case of small intestine serousal surface metastasis from ovarian papillary cystadenocarcinoma. ... features coupled with the CK7 immunoreactivity led to a diagnosis of high grade ovarian papillary cystadenocarcinoma. To the ... These findings indicate a tumor of high-grade malignancy with infiterative tumor cells resembling the papillary ovarian tumor ...
... kidney renal papillary cell carcinoma; LAML: acute myeloid leukemia; LIHC: liver hepatocellular carcinoma; LUAD: lung ... adenocarcinoma; LUSC: lung squamous cell carcinoma; MESO: mesothelioma; OV: ovarian serous cystadenocarcinoma; PAAD: pancreatic ...
CYSTADENOMA AND CYSTADENOCARCINOMA OF THE PANCREAS.. AU. BECKER WF, WELSH RA, PRATT HS ... of Intraductal papillary mucinous neoplasm of the pancreas (IPMN): Pathophysiology and clinical manifestations. 1 ...
Non-invasive intraductal papillary mucinous neoplasms. *Serous or mucinous cystadenoma or cystadenocarcinoma ...
Papillary cystadenocarcinoma of ovary. Thoracic radiculopathy. Information from references 2, 4, and 16 through 18. ...
Biliary cystic intraductal papillary mucinous tumor and cystadenoma/cystadenocarcinoma: differentiation by CT. Abdom Imaging. ... Cystadenocarcinoma calcifications tend to be thick and coarse. Cystadenocarcinomas may demonstrate papillary projections into ... encoded search term (Biliary Cystadenoma/Cystadenocarcinoma Imaging) and Biliary Cystadenoma/Cystadenocarcinoma Imaging What to ... Biliary Cystadenoma/Cystadenocarcinoma Imaging. Updated: Nov 28, 2015 * Author: Mohammad Alobaidi, MD; Chief Editor: John ...
Study Ch 7: neoplasia flashcards from Caitlin miller
Diseases associated with HSPA2 include Inflammatory Bowel Disease 3 and Papillary Cystadenocarcinoma. Among its related ...
Cystadenocarcinoma, Serous. A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. ... Carcinoma, Papillary, Follicular. A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and ... The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly ... papillary gain. Due to the inconsistent and insufficient data available regarding papillary reconstruction, it was difficult to ...
Cystadenocarcinoma, Papillary. An adenocarcinoma in which the tumor elements are arranged as finger-like processes or as a ... Cystadenocarcinoma, Mucinous. A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. ...
Carcinoma, Papillary / metabolism* * Carcinoma, Papillary / pathology * Cystadenocarcinoma, Serous / metabolism* * ... Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways Oncogene. 2004 ... The data generated in this study represent a comprehensive list of genes aberrantly expressed in serous papillary ovarian ... we used oligonucleotide microarrays comprising over 40,000 features to profile 37 advanced stage papillary serous primary ...
Carcinoma, Papillary* / diagnosis. Carcinoma, Renal Cell / diagnosis. Choristoma* / diagnosis. Cystadenocarcinoma, Mucinous* / ... Histopathologic analysis of the surgical specimen revealed mild differentiated papillary renal carcinoma, intraductal papillary ... A case of pancreatic heterotopy of duodenal wall, intraductal papillary mucinous tumor and intraepithelial neoplasm of pancreas ...
Cystadenocarcinoma, Papillary / genetics* * Cystadenocarcinoma, Papillary / pathology* * Cystadenoma, Serous / genetics* * ...
Ovarian Serous Cystadenocarcinoma, Stage Iii, Grade 2 (1) * Ovarian Teratoma (1) * Papillary Cystadenocarcinoma Of The Ovary (1 ... Grade 3, Stage Iiic, Malignant Papillary Serous Adenocarcino... (1) * Grade 3, Stage Iiic, Primary Malignant Adenocarcinoma; ...
Cystadenocarcinoma, Serous. .map{width:100%;height:300px;margin-bottom:15px}. Name. Location. ... Uterine papillary serous carcinoma (UPSC) is an uncommon, but aggressive variant of. endometrial carcinoma that has a high ... A Pilot Phase II Trial of Radiation Therapy "Sandwiched" Between Paclitaxel and Carboplatin in Patients With Uterine Papillary ... A Pilot Phase II Trial of Radiation Therapy "Sandwiched" Between Paclitaxel and Carboplatin in Patients With Uterine Papillary ...
  • A simple, papillary cystic adenocarcinoma of the mammary gland with metastases to the internal iliac and mesenteric lymph nodes, liver, and spleen was observed in a 12 to 13 year old female black-footed ferret (Mustela nigripes). (usgs.gov)
  • To study the prognosis of patients with stage IIIC/IV primary peritoneal serous papillary carcinoma (PSPC) (study group) compared with that of patients with epithelial ovarian carcinoma (EOC) (control group). (labome.org)
  • Mucoepidermoid carcinoma, salivary duct carcinoma, and cystadenocarcinoma are part of this group of mucin-producing tumors, among others. (bvsalud.org)
  • For younger women (ages 40-45 years) whose mothers were affected with endometrial malignancies, the risk of developing endometrioid carcinoma was slightly greater than the risk of developing papillary serous cystadenocarcinoma. (wiley.com)
  • Uterine papillary serous carcinoma (UPSC) is an uncommon, but aggressive variant of endometrial carcinoma that has a high recurrence rate and poor response to therapy. (clinicaltrials.gov)
  • A case of pancreatic heterotopy of duodenal wall, intraductal papillary mucinous tumor and intraepithelial neoplasm of pancreas, papillary carcinoma of kidney in a single patient. (biomedsearch.com)
  • Histopathologic analysis of the surgical specimen revealed mild differentiated papillary renal carcinoma, intraductal papillary mucinous adenoma of the pancreatic head, foci of intraepithelial pancreatic neoplasm and pancreatic heterotopy of duodenal muscular and submucosal layers. (biomedsearch.com)
  • 1. Histologically documented uterine papillary serous carcinoma (UPSC) with no visible residual disease. (knowcancer.com)
  • Determine the therapeutic activity of paclitaxel in patients with refractory or recurrent endometrial papillary carcinoma. (knowcancer.com)
  • Histological diagnosis was serous papillary carcinoma of the left ovary. (hindawi.com)
  • A rare case of ovarian serous papillary carcinoma recurring as malignant mixed Mullerian tumor is reported. (hindawi.com)
  • We report a case of ovarian serous papillary carcinoma which recurred as carcinosarcoma which is homolog type in contrast to others in the literature. (hindawi.com)
  • Twenty samples were taken from the left ovarian tumor and a histological diagnosis of serous papillary carcinoma (grade III in a scale from I to III) with capsule invasion was made. (hindawi.com)
  • To present the clinical and laboratory characteristics, as well as the management, of patients with primary peritoneal serous papillary carcinoma (PPSPC). (springer.com)
  • Bloss JD, Liao SY, Buller RE et al (1993) Extraovarian peritoneal serous papillary carcinoma: a case-control retrospective comparison to papillary adenocarcinoma of the ovary. (springer.com)
  • Considering the histological features of LGCCC, it should be distinguished with papillocystic variant of acinic cell carcinoma, conventional salivary duct carcinoma, cystadenocarcinoma, polymorphous low-grade adenocarcinoma, carcinoma ex pleomorphic adenoma and mammary analogue secretory carcinoma . (humpath.com)
  • Yang J , Li H , Hu S , Zhou Y , . ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19. (aging-us.com)
  • Angiotensin-converting enzyme 2 (ACE2) is a member of the renin-angiotension system, however, the correlation between ACE2 and prognosis in UCEC (Uterine Corpus Endometrial Carcinoma) and KIRP (Kidney Renal Papillary Cell Carcinoma) is not clear. (aging-us.com)
  • KIRP (Kidney Renal Papillary Cell Carcinoma) accounts for 15%-20% of renal cancer [ 10 ]. (aging-us.com)
  • The postoperative diagnoses were 5 with ductal adenocarcinoma, 3 with invasive intraductal papillary mucinous neoplasm, 1 with mucinous cystadenocarcinoma, 1 with neuroendocrine carcinoma, and 1 with pancreas metastasis from a renal cell carcinoma. (ovid.com)
  • Magnetic resonance imaging (MRI) shows massive ascites and nodular/irregular thickening of the mesentery and peritoneum and a small mass suspected in the right normal ovary and marked enhancement of the papillary projections. (hindawi.com)
  • Swerdlow M (1959) Mesothelioma of the pelvic peritoneum resembling papillary cystadenocarcinoma of the ovary. (springer.com)
  • Papillary projections are characteristic and may be more of a feature with borderline than malignant serous cystadenocarcinoma of the ovary . (radiopaedia.org)
  • 2. Burkholz KJ, Wood BP, Zuppan C. Best cases from the AFIP: Borderline papillary serous tumor of the right ovary. (radiopaedia.org)
  • Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (wikipedia.org)
  • A) Sagittal T2-weighted fast spin-echo fat-suppressed, (B) postcontrast axial T1-weighted (T1W) fat-suppressed 3-dimensional (3D) gradient-recalled echo (GRE), and (C) sagittal T1W fat-suppressed 3D GRE contrast-enhanced images show a large midline pelvic cystic mass with papillary excrescence (arrowheads), which is consistent with ovarian cystadenocarcinoma. (medscape.com)
  • This tumor predominantly consists of intraductal components and frequently exhibits papillary-cystic or cribriform proliferation pattern . (humpath.com)
  • Mucinous cystic neoplasms of the liver [ 1 ], formerly known as bile duct/biliary cystadenoma and biliary cystadenocarcinoma [ 2 ], represent an enigmatic entity, characterised by unknown origin and peculiar morphology including the presence of ovarian-type stroma. (intechopen.com)
  • Endoscopic ultrasonography (EUS) identified 8 mm papillary projections in the cystic lesion, which was a key indication for surgery. (biomedcentral.com)
  • Pancreatic neueroendocrine tumors rarely undergo cystic changes but they are often misdiagnosed as pancreatic mucinous cystadenoma, mucinous cystadenocarcinoma, serous cystadenoma, and solid and cystic papillary tumors, or pseudocyst. (enets.org)
  • Although the clinical and pathological findings of hepatobiliary cystadenoma and cystadenocarcinoma have been well-described, it cannot be distinguished from one another by imaging findings including computed tomography (CT), magnetic resonance imagings (MRI) and ultrasound (US). (biomedcentral.com)
  • Although histopathological differentiation between hepatobiliary cystadenoma and cystadenocarcinoma is indisputable, it is unknown whether hepatobiliary cystadenocarcinomas arise de-novo come or whether they arise from hepatobiliary cystadenomas. (biomedcentral.com)
  • However, they need to be differentiated from mucoepidermoid and papillary acinic cell tumors. (docphin.com)
  • Pancreatic neuroendocrine tumors (pNETs) and intraductal papillary mucinous neoplasms (IPMN) are increasingly recognized pancreatic tumors due to advances in imaging. (enets.org)
  • 1930 Concomitant Intraductal Papillary Mucinous Neoplasms and Neuroendocrine Tumors of the Pancreas: More than just a Coincidence? (enets.org)
  • Intraductal papillary mucinous neoplasms (IPMNs) and pancreatic neuroendocrine tumors (pNETs) are rare tumors. (enets.org)
  • Smear preparations in all four cases were cellular, with numerous papillary projections, single cells, and sheets of cells in varying proportion in a proteinaceous to mucoid background. (docphin.com)
  • Papillary projections can be seen with both CT scanning and ultrasonography. (medscape.com)
  • Typically seen as bilateral adnexal masses with profuse papillary projections. (radiopaedia.org)
  • The cyst was located in the left lobe of the liver, was 6 cm in diameter, and did not exhibit calcification, septa or papillary projections. (biomedcentral.com)
  • The resected specimen had a solid component with papillary projections and the cyst was filled with liquid-like muddy bile. (biomedcentral.com)
  • Fistula formation has been reported in intraductal papillary-mucinous neoplasms (IPMNs) with or without invasion of the adjacent organs. (biomedcentral.com)
  • Intraductal papillary-mucinous neoplasms (IPMNs) of the pancreas have unique clinico-pathological characteristics and show a wide spectrum of histological types, ranging from adenomatous hyperplasia to invasive cancer. (biomedcentral.com)
  • Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian tumours in women aged over 20 in the United States. (wikipedia.org)
  • Papillary serous cystadenocarcinomas may exhibit psammoma bodies upon histopathology. (wikipedia.org)
  • Papillary cystadenocarcinomas of the parotid are rare but can be accurately diagnosed on FNAC. (docphin.com)
  • Papillary cystadenocarcinoma, in turn, comprises an extremely rare lesion, accounting for 0.5% of all epithelial lesions affecting the salivary glands 2 and according to the second largest survey on cystadenocarcinomas described in the literature, the highest prevalence is also observed in the major salivary glands 3 . (bvsalud.org)
  • Ovarian papillary cystadenocarcinomas in a green iguana (Iguana iguana). (biomedcentral.com)
  • This cyst is lined by atypical epithelial cells, and it contains papillary processes. (greek.doctor)
  • In order to obtain a whole genome assessment of aberrant gene expression in advanced ovarian cancer, we used oligonucleotide microarrays comprising over 40,000 features to profile 37 advanced stage papillary serous primary carcinomas. (nih.gov)
  • The papillary structure of the mass strongly suggested ovarian cancer. (spandidos-publications.com)
  • Solid papillary neoplasm of the pancreas: a case report. (biomedsearch.com)
  • Aetna considers pancreaticoduodenectomy (also known as Whipple resection) medically necessary for the treatment of intraductal papillary mucinous neoplasm of the pancreas (IPMN) with high-grade dysplasia or invasive cancer. (aetna.com)
  • Clinical case description of a papillary mucinous cystadenocarcinoma, extremely rare malignant tumor in the salivary gland and difficult to diagnose, in geriatric patient. (bvsalud.org)
  • Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from (1) the infarction and calcification of papillae tips and (2) calcification of intralymphatic tumor thrombi. (wikipedia.org)
  • Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer University School of Medicine. (wikipedia.org)
  • En bloc resection including the distal region of the pancreas, spleen, stomach and part of the transverse colon was performed under the pre- and intraoperative diagnosis of an invasive malignant IPMN. (biomedcentral.com)
  • MRI signal characteristics of biliary cystadenoma/cystadenocarcinoma are not specific for the disease. (medscape.com)
  • These findings indicate a tumor of high-grade malignancy with infiterative tumor cells resembling the papillary ovarian tumor in the serosal surface of the small intestine along with an intact serosa. (biomedcentral.com)