A group of compounds with an 8-carbon ring. They may be saturated or unsaturated.
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The protein complement of an organism coded for by its genome.
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Organic compounds composed exclusively of carbon and hydrogen. Three or more carbon atoms are arranged in a cyclic structure and they possess aliphatic properties.
Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)
Six-carbon alicyclic hydrocarbons.
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.
A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)
Acyclic branched or unbranched hydrocarbons having two carbon-carbon double bonds.
A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.
Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.
Collections of systematically acquired and organized information resources, and usually providing assistance to users. (ERIC Thesaurus, http://www.eric.ed.gov/ accessed 2/1/2008)

Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice. (1/91)

AIM: To explore whether the methylenedioxy group and cyclooctadiene ring of the dibenzocyclooctadiene skeleton of schisandrins (Sch) play a role in the liver mitochondrial glutathione status enhancing activity. METHOD: The effects of three dibenzocyclooctadiene derivatives, Sch A, Sch B, Sch C, and a synthetic intermediate of Sch C, (dimethyl biphenyl dicarboxylate, DBD) on carbon tetrachloride (CCl4)-hepatotoxicity and liver mitochondrial glutathione status were examined in mice. RESULTS: Pretreating mice with intragastric Sch B, Sch C, or DBD 1.mmol.kg-1.d-1 for 3 d protected against CCl4-hepatotoxicity. The hepatoprotection afforded by Sch B or Sch C pretreatment was associated with increases in liver mitochondrial reduced glutathione (mtGSH) level and glutathione reductase (mtGRD) activity, an indication of enhanced mitochondrial glutathione status. In contrast, the hepatoprotective action of DBD was not accompanied by any detectable changes in mtGSH level and mtGRD activity. CONCLUSION: Both the methylenedioxy group and the cyclooctadiene ring of the dibenzocyclooctadiene molecule are important structural determinants in the enhancement of liver mitochondrial glutathione status.  (+info)

Effect of plant matrix and fluid ethanol concentration on supercritical fluid extraction efficiency of schisandrin derivatives. (2/91)

An investigation of the effect of plant matrix on the supercritical fluid extraction efficiency of five schisandrin derivatives is reported, exhibiting a great difference with respect to extraction efficiency depending on the matrix. Pure supercritical CO2 at 60 degrees C and 34.0 MPa cannot fully recover schisandrin derivatives from the leaves as much as from the other matrices. Only 36.9% of these compounds are extracted from leaves of Schisandra chinensis by supercritical CO2 in comparison with organic solvent extraction. However, more than 80% of schisandrin derivatives are obtained from both stem and fruit parts. Ethanol addition also shows a different effect depending on plant matrix; that is, CO2 modified with 10% ethanol could enhance the yield of schisandrin derivatives from leaves by four times when compared with that of pure CO2, but it has little effect on both stems and fruits.  (+info)

Effects of schisandrin B pretreatment on tumor necrosis factor-alpha induced apoptosis and Hsp70 expression in mouse liver. (3/91)

Tumor necrosis factor-alpha (TNFalpha) could cause apoptosis in hepatic tissue of D-galactosamine sensitized mice, as evidenced by the increase in the extent of DNA fragmentation. The hepatic apoptosis induced by TNFalpha was associated with hepatocellular damage as assessed by plasma alanine aminotransferase activity. Schisandrin B (Sch B) pretreatment at daily doses ranging from 0.5 to 2 mmol/kg for 3 days caused a dose-dependent protection against TNFalpha-induced apoptosis in mice. The hepatoprotection was accompanied by a parallel reduction in the extent of hepatocellular damage. The same Sch B pretreatment regimens increased hepatic Hsp70 level in a dose-dependent manner. The relevance of Sch B-induced increase in Hsp70 expression to the prevention of TNFalpha-triggered hepatic apoptosis remains to be elucidated.  (+info)

Enantiodifferentiating Z-E photoisomerization of cyclooctene sensitized by DNA and RNA. (4/91)

DNA and RNA have been shown for the first time to function as chiral photosensitizers in aqueous solution, to effect the enantiodifferentiating photoisomerization of (Z)-cyclooctene (1Z), giving the chiral (E)-isomer in enantiomeric excesses (ee's) of up to 15%. In order to elucidate the effect of nucleotide sequence, enantiodifferentiating photoisomerization of 1Z was also performed using oligo and homopolynucleotides as chiral sensitizer. The -18.8% ee was observed by using d(T)15.d(A)15 as sensitizer, whereas sensitization by the poly(U).poly(A) duplex gave only racemic (E)-cyclooctene. From these results, oligothymidine sequence is essential for efficient enantioselective photoisomerization of 1Z.  (+info)

Effect of schisandrin B on lipoperoxidative damage to plasma membrane of rat liver in vitro. (5/91)

The effect of schisandrin B (Sin B) on oxygen free radicals--induced lipoperoxidative damage to plasma membrane of rat hepatocytes was investigated. When the plasma membrane of rat hepatocytes was incubated with iron/cysteine or Vit C/NADPH, the production of malondialdehyde (MDA) and consumption of NADPH increased, while the membrane fluidity reduced. Addition of Sin B (3-25 micrograms.ml-1) to the incubation mixture inhibited all these alterations of the plasma membrane induced by iron/cysteine and Vit C/NADPH. The results indicated that Sin B could maintain membrane stability of rat hepatocytes under oxidative stress.  (+info)

The anti-HBsAg (human type B hepatitis, surface antigen) and anti-HBeAg (human type B hepatitis, e antigen) C18 dibenzocyclooctadiene lignans from Kadsura matsudai and Schizandra arisanensis. (6/91)

The C(18) dibenzocyclooctadiene lignans including three novel schizanrin F (1), G (2), H (3), along with the known kadsurarin (4), were isolated from Kadsura matsudai. A new C(19) homolignan named schiarisanrin E (5), together with the known C(18) lignans, gomisin B (6), G (7) and (+)-gomisin K(3) (8) were obtained from Schizandra arisanensis. Gomisin B, G and (+)-gomisin K(3) showed moderate to strong activity for antihepatitis in anti-HBsAg (human type B hepatitis, surface antigen) and/or anti-HBeAg (human type B hepatitis, e antigen) tests. The structural elucidations of new compounds 1-3 and 5 were based on two-dimensional (2D) NMR techniques including COSY, HMQC, HMBC, NOESY and CD spectra. Preliminary structure-activity relationship studies for these isolated lignans are also discussed.  (+info)

Novel Fusicoccins R and S, and the fusicoccin S aglycon (phomopsiol) from Phomopsis amygdali niigata 2-A, and their seed germination-stimulating activity in the presence of abscisic acid. (7/91)

Our search for new 3-hydroxyfusicoccins structurally related to cotylenin A from a culture of Phomopsis amygdali Niigata 2-A resulted in the isolation of novel 3-hydroxy fusicoccins, called fusicoccins R and S, and the fusicoccin S aglycon, called phomopsiol, together with known 3alpha-hydroxyfusicoccin J. The structure of phomopsiol was identified as that of O-demethyl-3-epicotylenol based on spectroscopic evidence. The structures of fusicoccins R and S were also determined to be those of 3'-deacetyl-3alpha-hydroxyfusicoccin A and 3beta-hydroxy-3-epifusicoccin H. The lettuce seed germination-stimulating activity of fusicoccins R and S, phomopsiol and 3alpha-hydroxyfusicoccin J was examined in the presence of ABA; fusicoccin R and 3alpha-hydroxyfusicoccin J were highly active, while fusicoccin S and phomopsiol were inactive. The possible biosynthetic relationships among these novel fusicoccins having a 3alpha- or 3beta-hydroxy group in their diterpene moiety are briefly discussed.  (+info)

Antioxidative effect of schisanhenol on human low density lipoprotein and its quantum chemical calculation. (8/91)

AIM: To investigate the effect of schisanhenol (Sal) on copper ion-induced oxidative modulation of human low density lipoprotein (LDL). METHODS: The antioxidative activity of eight schisandrins (DCL) on microsome lipid peroxidation induced by Vit C/NADPH system was first observed, and then, the effect of Sal on Cu2+-induced human LDL oxidation was studied. The generation of malondialdehyde (MDA), lipofuscin, reactive oxygen species (ROS), consumption of a-tocopherol as well as electrophoretic mobility of LDL were determined as criteria of LDL oxidation. Finally, the quantum chemical method was used to calculate the theoretical parameters of eight DCL for elucidating the difference of their antioxidant ability. RESULTS: Sal was shown to be the most active one among eight schizandrins in inhibiting microsome lipid oxidation induced by Vit C/NADPH. Sal 100, 50, and 10 micromol/L inhibited production of MDA, lipofuscin and ROS as well as the consumption of a-tocopherol in Cu2+-induced oxidation of human LDL in a dose-dependent manner. Sal also reduced electrophoretic mobility of the oxidized human LDL. Further study of quantum chemistry found that Sal was the strongest one among eight DCL to scavenge O2, R, RO and ROO radicals. CONCLUSION: Sal has antioxidative effect on human LDL oxidation. The mechanism of Sal against LDL oxidation may be through scavenging free radicals.  (+info)

Tetrazine-trans-cyclooctene ligations are remarkably fast and selective reactions even at low micro-molar concentrations. In bioorthogonal radiochemistry, tools that enable conjugation of radioactive probes to pre-targeted vectors are of great interest. Herein, we describe the successful development of the f
The synthesis of TG in humans mainly involves exogenous and endogenous pathways. The exogenous pathway starts with the intestinal absorption of TG from dietary sources in the form CM [23]. In the endogenous pathway, TG is synthesized using fatty acids in the liver and it is carried by TG-rich VLDL into bloodstream [24]. Therefore, TG in the blood mainly exists in the form of CM and/or VLDL. In the present study, Sch B treatment increased serum TG levels in a time-/dose-dependent manner from 6 to 96 h post-dosing. However, the serum TC level was elevated between 24 and 48 h after Sch B treatment. Scotts plot analysis showed that the potency of Sch B-induced elevation in serum TG is about 15.8-fold higher than that of TC. Moreover, no significant changes were detected in serum HDL and LDL levels at all time points following the administration of Sch B (data not shown). High blood TG levels in both animals and humans result from either the suppression of TG catabolic pathway or promotion of TG ...
Bridging of long peripheral nerve spaces continues to be a significant clinical problem. regeneration and peripheral glial cells such as Schwann cells stay uncertain. It can be apparent that surface area topography affects cell behavior and [19 considerably, 20]. Differing topography of electrospun materials alters cell adhesion, growing, expansion, migration and difference in bone tissue nerve and [21] regeneration [22] while good while in guiding come cell destiny [23]. Substrate curvature modulates neurite extension ECM and [24] might play a part in buy Schisandrin B effecting this behavior of cells [25]. The present research explores the romantic relationship between buy Schisandrin B differential proteins adsorption on electrospun PAN-MA movies and soft solvent cast PAN-MA movies. 2. Methods and Materials 2.1 Manufacturing of plastic films with in-line and soft topographies Plastic solutions (7%) had been produced by dissolving poly(acrylonitrile-co-methylacrylate) (PAN-MA) (Sigma, MW 8000) ...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers, Hiu Yee Kwan, Xuyan Niu, Wenlin Dai, Tiejun Tong, Xiaojuan Chao, Tao Su, Chi Leung Chan, Kim Chung Lee, Xiuqiong Fu, Hua Yi, Hua Yu, Ting Li, Anfernee Kai Wing Tse, Wang Fun Fong, Si-Yuan Pan, Aiping Lu, and Zhi-Ling Yu. ...
A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using99mTc- and177Lu-Labeled Tetrazines.. Journal of Medicinal Chemistry Journal of Medicinal and Pharmaceutical Chemistry. 59:9381-9389. 2016 ...
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Several Exothermic reactions application notes. Reaction difficult to control due to its fast reaction rate and exothermic character and is therefore traditionally performed at low temperature can be performed at high temperatures with use of flow chemistry
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Schisandra sphenanthera is a deciduous Climber growing to 7 m (23ft) at a medium rate. It is hardy to zone (UK) 7 and is not frost tender. It is in flower from Apr to May, and the seeds ripen from Jul to September. The flowers are dioecious (individual flowers are either male or female, but only one sex is to be found on any one plant so both male and female plants must be grown if seed is required)The plant is not self-fertile. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils and prefers well-drained soil. Suitable pH: acid, neutral and basic (alkaline) soils. It can grow in full shade (deep woodland) or semi-shade (light woodland). It prefers moist soil.
The extraction optimization and composition analysis of polyphenols in the fresh pulp of Wuweizi (Schisandra chinensis) have been investigated in this study. The extraction process of polyphenols from Wuweizi pulp was optimized using Random-Centroid Optimization (RCO) methodology. Six factors including liquid and solid ratio, ethanol concentration, pH, temperature, heating time and extraction times, and three extraction targets of polyphenol content, antioxidant activity and extract yield were considered in the RCO program. Three sets of optimum proposed factor values were obtained corresponding to three extraction targets respectively. The set of optimum proposed factor values for polyphenol extraction given was chosen in further experiments as following: liquid and solid ratio (v/w) 8, ethanol 67.3% (v/v), initial pH 1.75, temperature 55 °C for 4 h and extraction repeated for 4 times. The Wuweizi polyphenol extract (WPE) was obtained with a yield of 16.37 mg/g and composition of polyphenols 1.847 mg
Schisandra - Review, facts, where does schisandra come from? Benefits for performance & stress, negatives, side effects, supplements, doses, stacking...
The Chinese herb Wu Wei Zi (Schisandra Fruit) is Sour, Warm, goes to the HT, KI, LU, and is in Herbs that Astringe, Stabilize, Bind.
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Hepatoprotective effects of Chinese herbal medicine Schisandra Chinensis (Schisandra) have been widely investigated. However, most studies were focused on its lignan extracts. We investigated the effects of Schisandra polysaccharide (SCP) in a mouse model of non-alcoholic fatty liver disease (NAFLD), and studied its effect on sterol regulatory element binding proteins (SREBPs) and the related genes. The mouse model of NAFLD was established by feeding mice with a high-fat diet for 16 weeks. Effect of SCP-treatment (100 mg/kg, once daily for 12 weeks) on biochemical parameters and liver histopathology was assessed. Relative levels of sterol regulatory element-binding proteins (SREBPs) and their gene expressions were determined by quantitative real-time polymerase chain reaction and Western Blot. SCP significantly reduced the liver index by 12.0%. Serum levels of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol, alanine aminotransferase and aspartate aminotransferase were
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Uses, Benefits, Cures, Side Effects, Nutrients in Schisandra. List of various diseases cured by Schisandra. How Schisandra is effective for various diseases is listed in repertory format. Names of Schisandra in various languages of the world are also given.
Copper free Click chemistry is a set of modern orthogonal bioconjugation reactions which take place in the absence of transition metals (like copper). The reactions include strain-promoted alkyne&ndah;azide cycloaddition (spAAC), and tetrazine - trans-cyclooctene ligation (TCO ligation).
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time heart disease, stroke, diabetes, high cholesterol, asthma, cigarette smoking, hepatitis, AID s and more. Glutathione provides the body with tools to fights off these threats naturally.. Healthy people also benefit from elevated glutathione levels through an enhanced ability to fight off toxins, infectious diseases, pre-cancerous cells and the aging process itself. Diminished glutathione levels are a symptom of aging and are particularly evident in such ailments as Parkinson s disease and Alzheimer s disease.. Glutathione is also important to physically active people. Many world-class athletes are discovering that well-maintained glutathione levels give them an edge over their competitors, bringing greater strength and endurance, decreased recovery time from injury, less muscle pain and fatigue and muscle-promoting activity.. Glutathione is an essential to anti-aging, master anti-oxidant, optimizing the immune system and detoxifying a long list of pollutants and carcinogens. However, the ...
(7R,8S)-3,4-methylenedioxy-3,4-dimethoxy -7,8-seco-7,7-epoxylignan-7,8-dione: from the fruits of Schisandra sphenanthera; structure in first source
Li, Jiali et al Wuzhi Tablet (Schisandra sphenanthera Extract) Is a Promising Tacrolimus-Sparing Agent for Renal Transplant Recipients Who Are CYP3A5 Expressers: a Two-Phase Prospective Study. Drug Metabolism and Disposition 45.11 (2017): 1114-1119. Web. 20 Jan. 2018. ...
Schisandra (pronounced shiz-an-dra) will pucker your mouth in more ways than one: Rolling the word across your tongue and chewing on the plants dried fruit can both be a taste treat.
Schisandra (pronounced shiz-an-dra) will pucker your mouth in more ways than one: Rolling the word across your tongue and chewing on the plants dried fruit can both be a taste treat.
Schisandra is a type of deciduous perennial vine that is native to East Asia and produces small red fruit that is commonly used...
Schisandra N-butanol extract improves synaptic morphology and plasticity in ovarectomized miceNeural Regen Res. 2012;7(18):1365-1369.
Urine PK for quantification of unchanged PF-03814375 and any identified metabolites. 24-hour urine collection at 8-hour intervals after the morning dose (Schedule [Sch] A Day 4, Sch B Day 9; last sample collected just prior to the morning dose on Sch A Day 5 or Sch B Day 10 in the expanded maximum tolerated dose (MTD) cohort only (≥ 10 participants in Sch A 80 mg and Sch B 50 mg groups). The lower limit of quantification (LLOQ) was 1 nanogram per milliliter (ng/mL). Clinical specimens with concentrations below the LLOQ were to be reported as below the limited of quantification (BLQ) 1 ng/mL ...
antibody-antibodies.com is the marketplace for research antibodies. Find the right antibody for your research needs. An integrated strategy using UPLC-QTOF-MSE and UPLC-QTOF-MRM (enhanced target) for pharmacokinetics study of wine processed Schisandra Chinensis fructus in rats.
Ingredients: Schisandra chinensis Seed, Spine Date Seed, Medulla Junci Flower, Licorice, Jujube Flavour: This blend is light and clear, with a fragrant, spicy smell. It is calming and tastes slightly sweet with a hint of licorice. To Make Fin
ATTO-TEC expands its portfolio of dye-labelled click-reagents, introducing ATTO tetrazines. Tetrazines readily react in a highly selective and bioorthogonal way with strained alkenes and alkynes. All ATTO tetrazines are based on 6-methyl-3-aryl-tetrazine (MeTet), which is characterized by high stability in aqueous media and rapid reaction with trans-cyclooctenes (TCO ...
ATTO-TEC expands its portfolio of dye-labelled click-reagents, introducing ATTO tetrazines. Tetrazines readily react in a highly selective and bioorthogonal way with strained alkenes and alkynes. All ATTO tetrazines are based on 6-methyl-3-aryl-tetrazine (MeTet), which is characterized by high stability in aqueous media and rapid reaction with trans-cyclooctenes (TCO ...
Schisandra on the other hand has the benefit of a couple of studies on horses. These only relate to its ability to improve performance, but there are plenty of human studies to support its use as a proper adaptogen. In both studies the horses were given a single dose or a placebo 30 minutes prior to exercise. The treated horses showed reduced heart and breathing rates and faster track times than the control group. In the older trial, this amounted to 1.8 seconds over 800 metres. Weve also had consistent feedback that endurance horses regularly given schisandra show quicker recovery and lower rejection rates at vet checks during competition. Schisandra is also a valuable liver herb and through stimulating liver activity it assists in reducing lactic acid levels.. So, adaptogens are an important and useful (though slightly roundabout) way to support your horses immune system. By moderating the stress response, they support optimal immune function and so aid in resistance to infection and ...
A facile synthesis of some 4-hydroxychalcones (3a-3j) by the condensation of various substituted benzaldehydes and 4-hydroxyacetophenone has been described. It is prepared by Claisen-Schmidt condensation. This is a comparative study of synthesizing compounds by conventional as well as non-conventional microwave irradiation in a commercially modified microwave oven and thus confirms the possible intervention of specific (non-thermal) microwave effect. The research is focused on the remarkable reaction rate enhancement by the use of various non-conventional microwave irradiations which minimizes the time and solvents in reactions. The microwave method offers several advantages like simple procedure, fast reaction rate, mild reaction condition and improved yields as compared to conventional methods. Variety of functional groups such as nitro, chloro, dimethylamino, methoxy, methyl and hydroxy survived under the reaction conditions. The structures of newly synthesized compounds have been established ...
7-Keto-dehydroepiandrosterone (Steroids) CAS Registry Number: 566-19-8 Synonyms: Androst-5-ene-7,17-dione,3b-hydroxy- (8CI);3b-Hydroxy-5-androstene ...
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TY - GEN. T1 - Fault injection-based test case generation for SOA-oriented software. AU - Zhang, Jia. AU - Qiu, Robin G.. PY - 2006. Y1 - 2006. N2 - The concept of Service Oriented Architecture (SOA) implies a rapid construction of a software system with components as published Web services. How to effectively and efficiently test and assess available Web services with similar functionalities published by different service providers remains a challenge. In this paper, we present a step-by-step fault injection-based automatic test case generation approach. Preliminary test results are also reported.. AB - The concept of Service Oriented Architecture (SOA) implies a rapid construction of a software system with components as published Web services. How to effectively and efficiently test and assess available Web services with similar functionalities published by different service providers remains a challenge. In this paper, we present a step-by-step fault injection-based automatic test case ...
See http://digital.library.louisville.edu/cdm/description/collection/royal#conditions for guidance on citing this item. To cite the digital version, add its Reference URL (found by following the link in the header above the digital file ...
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Schizandra berry is an adaptogen that aids stress & adrenal fatigue. Helps the liver & immune system function. It aids you to think clearly, increases your memory, is anti inflammatory & antioxidant.
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15d-PGJ2 ( 54 ) , A23187 ( 95 ) , acetyl-boswellic_acid ( 84 ) , AG1478 ( 39 ) , AGEs ( 15 ) , AH6809 ( 45 ) , Akt-I-1,2 ( 8 , 52 ) , angiotensin_2 ( 63 ) , anti-CD28 ( 91 ) , anti-CD3 ( 91 ) , anti-CD3/CD28 ( 33 , 88 ) , anti-LT(beta)R ( 98 ) , antitrypsin ( 59 ) , bacterial infection ( 24 , 86 ) , Bay_11-7082 ( 14 , 32 , 95 ) , BI-D1870 ( 15 ) , bisindolylmaleimide ( 91 ) , bortezomib ( 72 ) , botulinum_C3_toxin ( 63 ) , Ca(2+) ( 12 ) , calyculin_A ( 32 , 95 ) , CCL5 ( 52 ) , ciclosporin ( 33 ) , cisplatin ( 23 ) , CmpdA ( 23 ) , compound_1 ( 26 ) , deferoxamine ( 60 ) , delphinidin ( 55 ) , dimethylfumarate ( 22 ) , double-stranded_RNA ( 67 ) , DPI ( 25 , 57 ) , EGF ( 50 ) , epoxomicin ( 72 ) , ethanol ( 64 ) , farnesol ( 56 ) , fluid_shear_stress ( 45 ) , genistein ( 68 ) , gomisin_A ( 35 ) , gomisin_N ( 35 ) , GSK-3_inhibitor_X ( 42 ) , H-89 ( 45 ) , heat_shock ( 34 ) , IFN-gamma ( 42 ) , IKK-beta_inhibitor_IV ( 32 ) , IL-1a ( 62 , 73 , 74 ) , IL-1b ( 10 , 19 , 26 , 53 , 79 , 85 , 95 ) , ...
Semmelweis did not make one think what caused the alter of putrefying; he said the disability was not contagious, presum- ably because it could not submerge b decrease from at one self-possessed to anotherDrugs (limited anesthetics) that alter this conduction are not very selective, because the process of axonal conduction is on the brink of the yet in all neu- rons; therefore, a medicate that alters conduction require modify conduction in all cellsSetting aside how, in the subsequent, it is expected that all brand-new ideas, concepts, proposals, or adjuncts related to improv- ing the standing of health vigilance in prevailing and nutrition forward specifically purpose be accompanied around biggish misgiving, skepticism, appraisal, poison, controversies, challenges, and maquis to interchangeIrritation is fit a biomarker in the service of vascular and other diseases such as chronic obstruc- tive lung infirmity, peripheral artery occlusive disease, and diabetes ...
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Utilizată de peste 2000 de ani, Schisandra este originara din China fiind singura planta care are ... 21,47 LEI Ex Tax: 21,47 LEI ...
We systematically studied the heats of formation (HOFs) for a series of 3,3′-azobis-1,2,4, 5-tetrazine derivatives by den... ...
Ok, I\m just making a mini balloon and I need a chemical reaction to make it fly. So here are what I need: substances that will react slowly and that are exothermic as well. So far all I\ve found are stuff that have super fast reaction and that are so exothermic that they are likely to burn the balloon. Thanks in advance, JE
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The in vivo antioxidant action of a lignan-enriched extract of the fruit of Schisandra chinensis (FS) and an anthraquinone-containing extract of the root of Polygonum multiflorum (PME) was compared with their respective active constituents schisandrin B (Sch B) and emodin by examining their effect o …
0 (Bacterial Proteins); 0 (Cyclooctanes); 0 (Diterpenes); 0 (Enzymes); 0 (Polyisoprenyl Phosphates); EC 5.3.- (Intramolecular ...
Cyclooctanes / chemistry * Fibroblasts / metabolism * Glycoproteins / analysis * Glycoproteins / metabolism* * HEK293 Cells * ...
... cyclooctanes, biscyclobutanes, biscyclopentanes, biscyclohexanes, biscycloheptanes, biscyclooctanes, and norbornanes. It is ...
Fingerprint Dive into the research topics where Muhammad Sohail is active. These topic labels come from the works of this person. Together they form a unique fingerprint. ...
Cyclooctanes/administration & dosage. *Enzyme Activation/drug effects. *Enzyme Activation/genetics. *Heme Oxygenase-1/genetics ...
Shi, X., Mihaylova, V. T., Kuruvilla, L., Chen, F., Viviano, S., Baldassarre, M., Sperandio, D., Martinez, R., Yue, P., Bates, J. G., Breckenridge, D. G., Schlessinger, J., Turk, B. E. & Calderwood, D. A., 2 Aug 2016, In : PNAS. 113, 31, p. E4558-4566 9 p.. Research output: Contribution to journal › Article ...
Kleeman, S. O., Koelzer, V. H., Jones, H. J. S., Vazquez, E. G., Davis, H., East, J. E., Arnold, R., Koppens, M. A. J., Blake, A., Domingo, E., Cunningham, C., Beggs, A. D., Pestinger, V., Loughrey, M. B., Wang, L-M., Lannagan, T. R. M., Woods, S. L., Worthley, D., The S:CORT Consortium, Tomlinson, I. & 3 others, Dunne, P. D., Maughan, T. & Leedham, S. J., 2020, In : Gut. 69, p. 1092-1103 12 p.. Research output: Contribution to journal › Article ...
Cyclooctanes. *Fluorescent Dyes. *Recombinant Proteins. *Tetrazoles. Grant support. *MC_UP_A024_1008/Medical Research Council/ ...
Rowan, S. J., Barner-Kowollik, C., Klumperman, B., Gaspard, P., Grubbs, R. B., Hillmyer, M. A., Hutchings, L. R., Mahanthappa, M. K., Moatsou, D., OReilly, R. K., Ouchi, M., Sawamoto, M. & Lodge, T. P., Jan 19 2016, In : ACS Macro Letters. 5, 1, p. 1-3 3 p.. Research output: Contribution to journal › Review article ...
Animals , Cyclooctanes , Pharmacology , Female , Lignans , Pharmacology , Lung , Metabolism , Pathology , Male , Polycyclic ... Animals , Cyclooctanes , Pharmacology , Female , Lignans , Pharmacology , Lung , Metabolism , Male , Mitogen-Activated Protein ... Cyclooctanes , Dioxoles , Furaldehyde , Lignans , Oils, Volatile , Plant Extracts , Chemistry , Plants, Medicinal , Chemistry ... Countercurrent Distribution , Cyclooctanes , Chemistry , Dioxoles , Chemistry , Drugs, Chinese Herbal , Chemistry , Fruit , ...
cyclooctanes*caffeic acids*veratrum alkaloids*cordyceps*reishi. Genomes and Genes. *IL-1beta products*IL-10 products*Gpx1 ...
Cyclooctanes: 1. *poly-para-phenylene: 1. *(1,4)cyclooctadiene.HCl 5-(3-dimethylamino-2-methylpropyl)dibenzo(a,d) ...
Anti-Inflammatory Agents / Cells, Cultured / Cyclooctanes / Cytokines / Dose-Response Relationship, Drug / Humans / ...
The diformate of 1,5-dihydroxy-2,6-cyclooctyl oxide was synthesized from 1,5-cyclooctadiene. The dihydroxy compound itself was prepared from the diformate by alkaline hydrolysis and a diacetate derivative of the dihydroxy compound has been synthesized by standard methods. While the diformate and diacetate compounds are of general interest as intermediates for the synthesis of systems containing a cyclic ether structure, the dihydroxy compound is of particular interest as a monomer for the synthesis of unique polyester type polymers. A mechanism which involves a transannular reaction is postulated for the formation of cyclic ethers from the diene and this mechanism is compared to the standard olefin hydroxylation mechanism with respect to the products one would expect from each reaction sequence. The proof of structure of the compounds synthesized were determined by elemental and infrared analysis. Author
Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawleys Condensed Chemical Dictionary, 11th ed ...
Cyclooctanes , Dexrazoxane , Doxorubicin , Heart , Lignans , Myocardium , Polycyclic Compounds , Rats , Rats, Sprague-Dawley ...
Cyclooctanes - chemistry , Cyclopentanes - chemical synthesis , Lactams - chemistry , Arylation , Natural products , Aromatic ...
Cyclooctanes - metabolism , Cardiotonic Agents - chemistry , Lignans - metabolism , Cyclooctanes - therapeutic use , ... Benzimidazoles - metabolism , Heterocyclic Compounds, 4 or More Rings - metabolism , Cyclooctanes - chemistry , Polycyclic ...
... cyclohexenes cyclohexynes cyclometries cyclonically cyclonometer cyclononanes cyclononenes cyclononynes cyclooctanes ...
TY - JOUR. T1 - Chiral Co(II) metal-organic framework in the heterogeneous catalytic oxidation of alkenes under aerobic and anaerobic conditions. AU - Tuci, Giulia. AU - Giambastiani, Giuliano. AU - Kwon, Stephanie. AU - Stair, Peter C.. AU - Snurr, Randall Q.. AU - Rossin, Andrea. PY - 2014/3/7. Y1 - 2014/3/7. N2 - The chiral Co(II) MOF [Co(l-RR)(H2O)·H2O] ∞ [1; l-RR = (R,R)-thiazolidine-2,4-dicarboxylate] has been exploited in the catalytic oxidation of different alkenes (cyclohexene, (Z)-cyclooctene, 1-octene) using either tert-butyl hydroperoxide ( tBuOOH) or molecular oxygen (O2) as oxidants. Different chemoselectivities are observed, both substrate- and oxidant-dependent. A moderate enantioselectivity is also obtained in the case of prochiral precursors, revealing the chiral induction ability of the optically pure metal environment. The interaction of O2 with the exposed metal sites in 1 (after material preactivation and consequent removal of the coordinated aquo ligand) has been ...
Cyclooctanes [D02.455.426.392.368.408] + Cyclooctanes + * Cyclopentanes [D02.455.426.392.368.450] + Cyclopentanes + * ...