Cyclohexylamines
Platinum
Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
Spermidine Synthase
Industrial Microbiology
Oxidoreductases Acting on CH-NH Group Donors
Occupational Exposure
Transition Temperature
Nickel
Cyclohexanols
Amines
Stereoisomerism
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
A non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (ADRENOCORTICOTROPIC HORMONE) via the release of hypothalamic arginine vasopressin (ARGININE VASOPRESSIN) and CORTICOTROPIN-RELEASING HORMONE. (From J Pharmacol Exp Ther 1997;280(1):416-21)
Alkylation
Carmustine
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
Lymphangioleiomyomatosis
A disease characterized by the progressive invasion of SMOOTH MUSCLE CELLS into the LYMPHATIC VESSELS, and the BLOOD VESSELS. The majority of the cases occur in the LUNGS of women of child-bearing age, eventually blocking the flow of air, blood, and lymph. The common symptom is shortness of breath (DYSPNEA).
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Biodegradation of cyclohexylamine by Brevibacterium oxydans IH-35A. (1/124)
A bacterial strain capable of growing on cyclohexylamine (CHAM) was isolated by using enrichment and isolation techniques. The strain isolated, strain IH-35A, was classified as a member of the genus Brevibacterium. The results of growth and enzyme studies are consistent with degradation of CHAM via cyclohexanone (CHnone), 6-hexanolactone, 6-hydroxyhexanoate, and adipate. Cell extracts obtained from this strain grown on CHAM contained CHAM oxidase, and the model for CHAM oxidation by this enzyme was similar to the model for deamino oxidation of amine by amine oxidase. (+info)Anti-tumour activity of tachykinin NK1 receptor antagonists on human glioma U373 MG xenograft. (2/124)
Astrocytes harbour functional receptors to many neurotransmitters, including substance P (SP), an undecapeptide belonging to the tachykinin family of peptide transmitters. SP activates malignant glial cells to induce cytokine release and proliferation, both responses being relevant for tumour progression. In tumours developed in nude mice transplanted subcutaneously (s.c.) to U373 MG human glioma cells, the presence of SP was observed at immunohistochemistry. Although the administration of exogenous SP did not significantly affect the size or development of U373 MG xenograft, a role of SP in supporting glioma progression in vivo was highlighted by the tumour growth inhibition induced by highly specific and selective human tachykinin NK1 receptor antagonists (MEN 11467 and MEN 11149). The anti-tumour activity of MEN 11467 was observed both with s.c. or intravenous treatments and was partially reverted by the concomitant administration of exogenous SP. Doxorubicin did not show any activity in controlling U373 MG growth in this in vivo model. A novel therapeutic approach to treat malignant gliomas with tachykinin NK1 receptor antagonists is suggested by these findings. (+info)Long-term toxicity and carcinogenicity study of cyclamate in nonhuman primates. (3/124)
Twenty-one monkeys (cynomolgus, rhesus, African green) were fed cyclamate (100 mg/kg and 500 mg/kg) in the diet five times per week from a few days after birth and continuing for up to 24 years. Malignant tumors were diagnosed in three 24-year-old cyclamate monkeys; these were metastatic colon carcinoma (rhesus; 500 mg/kg), metastatic hepatocellular carcinoma (cynomolgus; 500 mg/kg), and a small, well differentiated adenocarcinoma of the prostate (cynomolgus; 100 mg/kg). Benign tumors were found at necropsy in three females; these were adenoma of the thyroid gland (rhesus; 100 mg/kg) and two cases of leiomyoma of the uterus (rhesus; 100 mg/kg and 500 mg/kg). No tumors were detected in an age-matched control group of 16 monkeys. Examination of the testes revealed complete testicular atrophy in one of the old cyclamate monkeys, and focal germ cell aplasia (Sertoli-only tubules) in two other cyclamate monkeys. Focal spermatogenic interruption (maturation arrest) at various germ cell levels mixed with normal spermatogenesis was observed in both the cyclamate-treated and the control monkeys, all of which were over 20 years old. Measurements of terminal cyclohexylamine concentrations showed that three of the males dosed with cyclamate at 500 mg/kg were high converters, with plasma concentrations comparable to the levels that produce testicular atrophy in rats. However, only one of the three high converters showed histologic evidence of irregular spermatogenesis. The overall conclusion is that the testicular abnormalities and the sporadic cases of different malignancies found after more than 20 years of dosing do not provide clear evidence of a toxic or carcinogenic effect of sodium cyclamate in monkeys. (+info)Effect of insulin on protein turnover in heart muscle. (4/124)
The effect of insulin on turnover of protein was investigated in isolated perfused rat hearts. The hormone lowered intracellular levels of nine amino acids and reduced or abolished net release of 10 amino acids and ammonia. The extent of the insulin effect on protein degradation was investigated by estimating the rate of dilution of the specific radioactivity of the free phenylalanine pool. Insulin concentrations greater than 200 microunits per ml reduced protein degradation and net phenlylalanine release. Protein degradation was estimated more directly by inhibiting reincorporation of nonradioactive phenylalanine from protein with cycloheximide. Addition of the inhibitor increased the estimated rates about 50%, but the magnitude of the hormone effect was similar. The latency of lysosomal enzymes in control and insulin-treated hearts was assessed by measuring activities of beta-acetylglucosaminidase and cathepsin D in heart homogenates in the presence and absence of Triton X-100. Perfusion with insulin-free buffer increased the activities assayable without detergent, but did not change total activities of these enzymes. Insulin decreased activities assayable without detergent and increased activities sedimenting in the 10-5 times g pellet. These studies showed that insulin restricted the rate of protein degradation in the isolated perfused rat heart. Concomitantly, the latency of lysosomal enzymes was increased when the hormone was provided. (+info)Effect of the long-acting tachykinin NK(1) receptor antagonist MEN 11467 on tracheal mucus secretion in allergic ferrets. (5/124)
1. We investigated the effect of MEN 11467 ((1R,2S)-2-N[1(H)indol-3-yl-carbonyl]-1-N-[N(alpha)(p-tolylacetyl)-N(alpha)(methy l)-D-3-(2-naphthyl)alanyl]diaminocyclohexane) on tachykinin-induced mucus secretion in ferret trachea in vitro and determined its effect on secretion by tracheae from allergic ferrets in response to allergen challenge. 2. Repeated administration of [Sar(9),Met(O(2))(11)]-substance P ([Sar(9)]SP, 1 microM) maintained mucus output above control values for at least 1.75 h. MEN 11467 inhibited secretion in a concentration-dependent manner with maximal inhibition at 10 microM and an approximate IC(50) of 0.3 microM. Inhibition by MEN 11467 (0.1--10 microM) was maintained, to varying degree, for at least 1.75 h after washout in the continued presence of [Sar(9)]SP. 3. In electrically stimulated tracheae, tachykininergic neural secretion was virtually abolished by 1 microM MEN 11467. 4. In tracheae from ovalbumin-sensitised animals, repeated administration of ovalbumin maintained mucus output above controls for 1.5 h. MEN 11467 inhibited ovalbumin-induced secretion in a concentration-dependent manner, with complete inhibition at 1 microM. Inhibition by MEN 11467 (1 and 10 microM) was maintained, to varying degree, after drug washout for the 1.5 h of ovalbumin stimulation. 5. MEN 11467 1 microM did not affect secretion induced by either acetylcholine or histamine, whereas 10 microM MEN 11467 did inhibit agonist-induced secretion. 6. We conclude that, in ferret trachea in vitro, MEN 11467 at concentrations of 0.1--1 microM is a long acting and selective inhibitor of tachykininergic-induced mucus secretion, and may have therapeutic potential for bronchial hypersecretion associated with allergic conditions, for example in asthma. (+info)2-chloroethanol formation as evidence for a 2-chloroethyl alkylating intermediate during chemical degradation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea. (6/124)
Chemical degradation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea or 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea in buffer under physiological conditions resulted in the formation of a significant quantity of 2-chlorethanol (18 to 25% of the initial nitrosourea concentration). Other degradation products observed included acetaldehyde (5 to 10%), vinyl chloride (1 to 2%), ethylene (1 to 2%), and cyclohexylamine (32%), but not 1,3-dicyclohexylurea. The 2-chlorethyl moiety of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea was trapped with halide ions, CI-, BR-, and I-, to form the corresponding dihaloethanes which were identified by gas chromatography-mass spectrometry techniques. High-pressure liquid chromatographic procedures were developed for the separation and quantiation of the nitrosoureas and many of their degradation products. It is postulated that a new mode of 1(2-chloreoethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea degradation can occur that is not the loss of the chloro group as chloride ion, but the loss of the N-3 hydrogen as a proton. Then the corresponding isocyanate and 2-chloroethyidiazene hydroxide are formed, with the latter intermidiate becoming an alkylating species, possibly in part as a 2-chloroethyl carbonium ion. (+info)In vitro and in vivo activities of aminoadamantane and aminoalkylcyclohexane derivatives against Trypanosoma brucei. (7/124)
We reported recently that the bloodstream form of the African trypanosome, Trypanosoma brucei, is sensitive to the anti-influenza virus drug rimantadine. In the present report we describe the trypanocidal properties of a further 62 aminoadamantane and aminoalkylcyclohexane derivatives. Seventeen of the compounds were found to be more active than rimantadine, with four inhibiting growth in vitro of T. brucei by >90% at concentrations of 1 microM. The most active derivative (1-adamantyl-4-amino-cyclohexane) was about 20 to 25 times more effective than rimantadine. We observed a correlation between structural features of the derivatives and their trypanocidal properties; hydrophobic substitutions to the adamantane or cyclohexane rings generally enhanced activity. As with rimantadine, the activity in vitro varied with the pH. T. brucei was more sensitive in an alkaline environment (including a normal bloodstream pH of 7.4) and less sensitive under acidic conditions. Tests for activity in vivo were carried out with a mouse model of infection with a virulent strain of T. brucei. Although the parasitemia was not eliminated, it could be transiently suppressed by >98% with the most active compounds tested. These results suggest that aminoadamantane derivatives could have potential as a new class of trypanocidal agents. (+info)B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus. (8/124)
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the newly discovered role of B-cell-activating factor (BAFF; also known as TALL-1, THANK, BlyS, and zTNF4) as a positive regulator of B-cell functions, such as B-cell activation and differentiation. Two members of the tumor necrosis factor(TNF)-receptor superfamily were recently identified as receptors for BAFF on B cells. The interaction between BAFF and its receptors may be important in the pathogenesis of lupus. Advances in our understanding of abnormalities in immune regulation in lupus might provide the opportunity to improve our current therapeutic approaches to this disorder. (+info)
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Catalysts | Free Full-Text | Nickel Catalyzed Conversion of Cyclohexanol into Cyclohexylamine in Water and Low Boiling Point...
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CYCLOHEXYLAMINE ( S KLOHEKS LAM N)
neutralising amine ,Cyclohexylamine/Morpholine | Biochemica
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Aniline
In aniline, the C−N bond length is 1.41 Å,[9] compared to 1.47 Å for cyclohexylamine,[10] indicating that there is partial π- ... Hydrogenation gives cyclohexylamine. Being a standard reagent in laboratories, aniline is used for many niche reactions. Its ...
Dicyclohexylamine
doi:10.1002/14356007.a02_001 U.S. Patent 5322965, "Process for the preparation of a mixture of cyclohexylamine and ... It is also obtained by reductive amination of cyclohexanone with ammonia or cyclohexylamine. Dicyclohexylamine may also be ... This method produces mainly cyclohexylamine with little dicyclohexylamine. Better results have been reported when the catalyst ... Dicyclohexylamine has applications that are similar to those of cyclohexylamine, namely the production of: antioxidants in ...
Acetaldehyde
... can condense with amines to yield imines; for example, with cyclohexylamine to give N-ethylidenecyclohexylamine. ...
Aniline
Hydrogenation gives cyclohexylamine. Being a standard reagent in laboratories, aniline is used for many niche reactions. Its ...
Sulfamic acid
Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate. Related compounds are also ...
Arylcyclohexylamine
An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned ... Other cycloalkane ring sizes have been experimented with than just purely thinking in terms of the cyclohexylamine. The ...
Cyclohexanone oxime
Typical of oximes, the compound can be reduced by sodium amalgam gives cyclohexylamine. It can also be hydrolyzed with acetic ...
N,N'-Dicyclohexylcarbodiimide
use palladium acetate, iodine, and oxygen to couple cyclohexyl amine and cyclohexyl isocyanide. Yields of up to 67% have been ...
Sodium cyclamate
... which itself is prepared by the sulfonation of cyclohexylamine. This can be accomplished by reacting cyclohexylamine with ... In 1966, a study reported that some intestinal bacteria could desulfonate cyclamate to produce cyclohexylamine, a compound ... with cyclohexylamine, chilled and filtered through a high speed centrifugal separator, dried, granulated and micro-pulverised ...
Cyclamic acid
"Quantitative hydrolysis of sodium cyclamate and calcium cyclamate to cyclohexylamine, followed by colorimetric analysis". ...
Dicyclohexylurea
It may be prepared by the reaction of cyclohexylamine and S,S-dimethyl dithiocarbonate. 1,3-Dicyclohexyl urea (DCU) is a potent ...
Aliens (film)
The aliens' acidic blood was a combination of tetrachloride, cyclohexylamine, acetic acid, and yellow dye. Winston added arms ...
Satraplatin
At this point the drug is structurally similar to cisplatin with the exception of one cyclohexylamine group in place of an ... June 1993). "Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active ...
2-Fluorodeschloroketamine
Their general structure consists of a cyclohexylamine unit with an aryl group attached to the same carbon as the amine. 2-FDCK ...
Discovery and development of dipeptidyl peptidase-4 inhibitors
A new potent, selective and orally bioavailable DPP-4 inhibitor was discovered by replacing the central cyclohexylamine in ...
Accelerant
... with a primary amine like cyclohexylamine or tert-Butylamine. Secondary amines like dicyclohexylamine can be used also but ...
Sodium cyclamate
In 1966, a study reported that some intestinal bacteria could desulfonate cyclamate to produce cyclohexylamine, a compound ... with cyclohexylamine, chilled and filtered through a high speed centrifugal separator, dried, granulated and micro-pulverised ... which itself is prepared by reacting freebase cyclohexylamine with either sulfamic acid or sulfur trioxide. Prior to 1973, ...
Cyclosarin
... with the other capsule containing either cyclohexanol or a mixture of cyclohexylamine and cyclohexanol. Iraq fielded munitions ...
Yves Jeannin
... cyclohexylamine)copper(II)) nitrate : an example of a flattened tetrahedral copper(II) complex », Inorg.Chem., 23, (1984), p. ...
C6H13N
... a heterocycle Cyclohexylamine, an amine derived from cyclohexane This set index page lists chemical structure articles ...
Cyclamate sulfohydrolase
... cyclohexylamine + sulfate Thus, the two substrates of this enzyme are cyclohexylsulfamate and H2O, whereas its two products are ... cyclohexylamine and sulfate. This enzyme belongs to the family of hydrolases, specifically those acting on sulfur-nitrogen ...
Sulfur vulcanization
... and sulfenamide derivatives are produced by reacting this with primary amines like cyclohexylamine or tert-Butylamine. ...
EPA list of extremely hazardous substances
Cyanogen bromide Cyanogen iodide Cyanophos Cyanuric fluoride Cycloheximide Cyclohexylamine Decaborane(14) Demeton Demeton-S- ...
Cyclohexylamine
... is listed as an extremely hazardous substance as defined by Section 302 of the U.S. Emergency Planning and ... Cyclohexylamine is an organic compound, belonging to the aliphatic amine class. It is a colorless liquid, although, like many ... Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide-based ... It is a useful intermediate in the production of many other organic compounds (e.g cyclamate) Cyclohexylamine is produced by ...
Cyclohexylamine oxidase
In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction cyclohexylamine + O2 ... Tokieda T, Niimura T, Takamura F, Yamaha T (April 1977). "Purification and some properties of cyclohexylamine oxidase from a ... The systematic name of this enzyme class is cyclohexylamine:oxygen oxidoreductase (deaminating). This enzyme participates in ... H2O ⇌ {\displaystyle \rightleftharpoons } cyclohexanone + NH3 + H2O2 The 3 substrates of this enzyme are cyclohexylamine, O2, ...
NIOSHTIC-2 Publications Search - 00098755 - Cyclohexylamine.
Cyclohexylamine - Wikipedia
Cyclohexylamine is listed as an extremely hazardous substance as defined by Section 302 of the U.S. Emergency Planning and ... Cyclohexylamine is an organic compound, belonging to the aliphatic amine class. It is a colorless liquid, although, like many ... Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide-based ... It is a useful intermediate in the production of many other organic compounds (e.g cyclamate) Cyclohexylamine is produced by ...
Cyclohexylamine
Cyclohexylamine oxidase - Wikipedia
In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction cyclohexylamine + O2 ... Tokieda T, Niimura T, Takamura F, Yamaha T (April 1977). "Purification and some properties of cyclohexylamine oxidase from a ... The systematic name of this enzyme class is cyclohexylamine:oxygen oxidoreductase (deaminating). This enzyme participates in ... H2O ⇌ {\displaystyle \rightleftharpoons } cyclohexanone + NH3 + H2O2 The 3 substrates of this enzyme are cyclohexylamine, O2, ...
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Cyclohexylamine
ICSC 1464 - 2,2'-DIMETHYL-4,4'-METHYLENEBIS(CYCLOHEXYLAMINE)
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4,4'-methylenebis(cyclohexylamine) - Registration Dossier - ECHA
From a structural perspective, this molecule does not possess any readily hydrolyzable functional groups (esters, carbamates, epoxides, halomethanes (containing 1-3 halogens), and specific alkyl halides), and thus is expected to be stable in water. Process chemistry and thermodynamics provide insight on the hydrolysis of primary amines. Some aliphatic primary amines are manufactured by reacting an aliphatic alcohol with ammonia over a catalyst. For these amines, it is known that the equilibrium of the process strongly favors amine production. Furthermore, the activation energy demand is of a magnitude that prevents these reactions from proceeding at ambient temperature and pH. ...
trans-methyl[2-(methylamino)cyclohexyl]amine - Registration Dossier - ECHA
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
trans-methyl[2-(methylamino)cyclohexyl]amine - Substance Information - ECHA
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Cyclohexylamine is a useful as an intermediate in organic synthesis. It acts as a precursor to prepare pendant-armed ... It is involved as a solvent in the synthesis of an inorganic-organic hybrid semiconductor, ZnS/CHA (CHA = cyclohexylamine) ... Towards the mechanism of the oxidation of cyclohexylamine by molecular oxygen over alumina-based catalysts. React. Kinet. Mech ... and theoretical calculations of cyclohexylamine. J. Mol. Struct. 2015, 1088, 169-178. ...
Catalysts | Free Full-Text | Nickel Catalyzed Conversion of Cyclohexanol into Cyclohexylamine in Water and Low Boiling Point...
In water, all the three catalysts achieved over 85% conversion and 90% cyclohexylamine selectivity in the presence of base and ... Nickel is found to demonstrate high performance in the amination of cyclohexanol into cyclohexylamine in water and two solvents ... Keywords: nickel; cyclohexanol; cyclohexylamine; base; hydrogen nickel; cyclohexanol; cyclohexylamine; base; hydrogen ►▼ ... Qi Y, Yu H, Cao Q, Dong B, Mu X, Mao A. Nickel Catalyzed Conversion of Cyclohexanol into Cyclohexylamine in Water and Low ...
RCSB PDB
- 1LU5: 2.4 Angstrom Crystal Structure of the Asymmetric Platinum Complex {Pt(ammine)(cyclohexylamine)}2+...
1761-71-3 - 4,4'-Diaminodicyclohexylmethane, mixture of stereoisomers, 98+% - 4,4'-Methylenebis(cyclohexylamine) - L09598 -...
WO2002024705A1 - Stereoselective process for preparing cyclohexyl amine derivatives
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150000003946 cyclohexylamines Chemical class 0.000 title 1 * 125000000217 alkyl group Chemical group 0.000 claims abstract ... Stereoselective process for preparing cyclohexyl amine derivatives Download PDF Info. Publication number. WO2002024705A1. ... WO2002024705A1 - Stereoselective process for preparing cyclohexyl amine derivatives - Google Patents. ...
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8.3 Effects to N,N-Dimethyl cyclohexyl Amine Industry. Chapter Nine Market Dynamics of N,N-Dimethyl cyclohexyl Amine Industry. ... Chapter Five Market Status of N,N-Dimethyl cyclohexyl Amine Industry. 5.1 Market Competition of N,N-Dimethyl cyclohexyl Amine ... 1.3 Status of N,N-Dimethyl cyclohexyl Amine Industry. Chapter Two Manufacturing Technology of N,N-Dimethyl cyclohexyl Amine. ... Chapter One Introduction of N,N-Dimethyl cyclohexyl Amine Industry. 1.1 Brief Introduction of N,N-Dimethyl cyclohexyl Amine. ...
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TRC | Details of CAS = 1566-15-0, ChemicalName = N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt, synonym =...
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cyclohexylamine-hydrochloride | VWR
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CYCLOHEXYLAMINE ( S KLOHEKS LAM N)
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Cyclohexanol3
- It is a useful intermediate in the production of many other organic compounds (e.g cyclamate) Cyclohexylamine is produced by two routes, the main one being the complete hydrogenation of aniline using some cobalt- or nickel-based catalysts: C6H5NH2 + 3 H2 → C6H11NH2 It is also prepared by alkylation of ammonia using cyclohexanol. (wikipedia.org)
- Nickel is found to demonstrate high performance in the amination of cyclohexanol into cyclohexylamine in water and two solvents with low boiling points: tetrahydrofuran and cyclohexane. (mdpi.com)
- Qi Y, Yu H, Cao Q, Dong B, Mu X, Mao A. Nickel Catalyzed Conversion of Cyclohexanol into Cyclohexylamine in Water and Low Boiling Point Solvents. (mdpi.com)
Amine3
- Cyclohexylamine is an organic compound, belonging to the aliphatic amine class. (wikipedia.org)
- Cyclohexylamine is a colorless to yellow liquid with an amine-like odor. (e-chemicalsource.com)
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Cyclohexanone1
- In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction cyclohexylamine + O2 + H2O ⇌ {\displaystyle \rightleftharpoons } cyclohexanone + NH3 + H2O2 The 3 substrates of this enzyme are cyclohexylamine, O2, and H2O, whereas its 3 products are cyclohexanone, NH3, and H2O2. (wikipedia.org)
Oxidase1
- Within this framework Leisch explored the chance of the bacterial cyclohexylamine oxidase (CHAO) produced from IH-35A alternatively biocatalyst for the formation of chiral principal amines using either kinetic quality or deracemization CX-4945 process14. (treeoflife-medicinals.com)
Hydrochloride2
- We are able to create a brand name in the market by offering our clients Cyclohexylamine Hydrochloride . (shreejipharmainternational.com)
- Cyclohexylamine Hydrochloride is used for the formulation of mucolytics, analgesics, and bronchodilators. (shreejipharmainternational.com)
1089181
- This information profile on cyclohexylamine (108918) is part of a group of 46 such profiles that provide information about chemicals or industrial processes considered to be potential occupational hazards. (cdc.gov)
Amines1
- Phenols can be efficiently reduced by sodium formate and Pd/C as the catalyst in water and in the presence of amines to give the corresponding cyclohexylamines. (wordpress.com)
Dicyclohexylamine1
- With many years' industry experiences in Mainland China, we have finished the first-phase construction of the production units for industrial cyclohexylamine, dicyclohexylamine and sodium cyclamate. (fvpfff.icu)
Cyclamate4
- It is the world's largest manufacturer of sodium cyclamate and China's biggest producer of cyclohexylamine. (fvpfff.icu)
- Cyclamate is the sodium or calcium salt of cyclamic acid (cyclohexanesulfamic acid), which itself is prepared by the sulfonation of cyclohexylamine . (wikipedia.org)
- Prior to 1973, Abbott Laboratories produced sodium cyclamate (Sucaryl) by a mixture of ingredients including the addition of pure sodium (flakes or rods suspended in kerosene) with cyclohexylamine, chilled and filtered through a high speed centrifugal separator, dried, granulated and micro-pulverised for powder or tablet usage. (wikipedia.org)
- In 1966, a study reported that some intestinal bacteria could desulfonate cyclamate to produce cyclohexylamine , a compound suspected to have some chronic toxicity in animals. (wikipedia.org)
Supplier1
- Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd) is supplier for Cyclohexylamine. (hotelpentagone.com)
Compounds1
- Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. (wikipedia.org)
Sulfamic1
- This can be accomplished by reacting cyclohexylamine with either sulfamic acid or sulfur trioxide . (wikipedia.org)
Aryl1
- Please explore our range of aryl cyclohexylamines products below and get in touch if you have any questions about how we can support you in your analytical testing. (lgcstandards.com)
Alkylamines1
- The purpose of this document is to investigate the whys and wherefores of Agent Scooby Doo in the product of cyclohexylamine induced reactions by comparitive study of psychotropic alkylamines drugs including Methylphenidate and Arylacetonitriles-derived alkylating solvents and their combined effects on human NMDA receptor. (openwetware.org)
Sodium1
- A liquid anticorrosion composition adapted for application to ferrous tubular goods is provided comprising an aqueous solution of cyclohexylammonium benzoate and a benzoate salt, which is preferably prepared by reacting cyclohexylamine with excess sodium benzoate in an aqueous alcohol solvent. (patentgenius.com)
Catalysts2
- Stolcova, M. Towards the mechanism of the oxidation of cyclohexylamine by molecular oxygen over alumina-based catalysts. (alfa.com)
- In water, all the three catalysts achieved over 85% conversion and 90% cyclohexylamine selectivity in the presence of base and hydrogen at a high temperature. (mdpi.com)
Inhibitor2
- The effect of cyclohexylamine (CHA), an inhibitor of Spm synthesis on pollen tube growth and germination percentage was also studied. (marmara.edu.tr)
- Morphological analysis of P. falciparum 3D7 following application of the PfSpdSyn inhibitor cyclohexylamine confirmed that parasite development was completely arrested at the early trophozoite stage. (biomedcentral.com)
Shenyu Energy1
- Groothandel Bulkvoorraad Cyclohexylamine Cas 108 91 8 met een hoge kwaliteit als een lage prijs / goedkoop, een van de toonaangevende merken van Bulkvoorraad Cyclohexylamine Cas 108 91 8 uit China, Shenyu Energy (Shandong) Development Co. Ltd. (zgshenyu.com)
Organic Chemicals1
- 1. Cyclohexylamine and 2,6-dimethylaniline were obtained from Eastman Organic Chemicals and were redistilled prior to use. (orgsyn.org)
Gram1
- The protocol was developed into a continuous-flow production of cyclohexylamines in gram scale achieving very efficient preliminary results (TON 32.7 and TOF 5.45 h -1 ). (wordpress.com)
Salt1
- N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt is a cytotoxic metabolite of Cyclophosphamide (C988580). (trc-canada.com)
Synthesis2
China1
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