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Prevention and therapy of cancer by dietary monoterpenes. (1/379)
Monoterpenes are nonnutritive dietary components found in the essential oils of citrus fruits and other plants. A number of these dietary monoterpenes have antitumor activity. For example, d-limonene, which comprises >90% of orange peel oil, has chemopreventive activity against rodent mammary, skin, liver, lung and forestomach cancers. Similarly, other dietary monoterpenes have chemopreventive activity against rat mammary, lung and forestomach cancers when fed during the initiation phase. In addition, perillyl alcohol has promotion phase chemopreventive activity against rat liver cancer, and geraniol has in vivo antitumor activity against murine leukemia cells. Perillyl alcohol and d-limonene also have chemotherapeutic activity against rodent mammary and pancreatic tumors. As a result, their cancer chemotherapeutic activities are under evaluation in Phase I clinical trials. Several mechanisms of action may account for the antitumor activities of monoterpenes. The blocking chemopreventive effects of limonene and other monoterpenes during the initiation phase of mammary carcinogenesis are likely due to the induction of Phase II carcinogen-metabolizing enzymes, resulting in carcinogen detoxification. The post-initiation phase, tumor suppressive chemopreventive activity of monoterpenes may be due to the induction of apoptosis and/or to inhibition of the post-translational isoprenylation of cell growth-regulating proteins. Chemotherapy of chemically induced mammary tumors with monoterpenes results in tumor redifferentiation concomitant with increased expression of the mannose-6-phosphate/insulin-like growth factor II receptor and transforming growth factor beta1. Thus, monoterpenes would appear to act through multiple mechanisms in the chemoprevention and chemotherapy of cancer. (+info)Biosynthesis of 3-acetyldeoxynivalenol and sambucinol. Identification of the two oxygenation steps after trichodiene. (2/379)
The first two oxygenation steps post-trichodiene in the biosyntheses of the trichothecenes 3-acetyldeoxynivalenol and sambucinol were investigated. The plausible intermediates 2-hydroxytrichodiene (2alpha- and 2beta-) and 12,13-epoxytrichodiene and the dioxygenated compounds 12,13-epoxy-9,10-trichoene-2-ol (2alpha- and 2beta-) were prepared specifically labeled with stable isotopes. They were then fed separately and/or together to Fusarium culmorum cultures, and the derived trichothecenes were isolated, purified, and analyzed. The stable isotopes enable easy localization of the labels in the products by 2H NMR, 13C NMR, and mass spectrometry. We found that 2alpha-hydroxytrichodiene is the first oxygenated step in the biosynthesis of both 3-acetyldeoxynivalenol and sambucinol. The stereoisomer 2beta-hydroxytrichodiene and 12,13-epoxytrichodiene are not biosynthetic intermediates and have not been isolated as metabolites. We also demonstrated that the dioxygenated 12, 13-epoxy-9,10-trichoene-2alpha-ol is a biosynthetic precursor to trichothecenes as had been suggested in a preliminary work. Its stereoisomer was not found in the pathway. A further confirmation of our results was the isolation of both oxygenated trichodiene derivatives 2alpha-hydroxytrichodiene and 12,13-epoxy-9, 10-trichoene-2alpha-ol as natural metabolites in F. culmorum cultures. (+info)Adenosylcobalamin-mediated methyl transfer by toluate cis-dihydrodiol dehydrogenase of the TOL plasmid pWW0. (3/379)
We identified and characterized a methyl transfer activity of the toluate cis-dihydrodiol (4-methyl-3,5-cyclohexadiene-cis-1, 2-diol-1-carboxylic acid) dehydrogenase of the TOL plasmid pWW0 towards toluene cis-dihydrodiol (3-methyl-4,5-cyclohexadiene-cis-1, 2-diol). When the purified enzyme from the recombinant Escherichia coli containing the xylL gene was incubated with toluene cis-dihydrodiol in the presence of NAD+, the end products differed depending on the presence of adenosylcobalamin (coenzyme B12). The enzyme yielded catechol in the presence of adenosylcobalamin, while it gave 3-methylcatechol in the absence of the cofactor. Adenosylcobalamin was transformed to methylcobalamin as a result of the enzyme reaction, which indicates that the methyl group of the substrate was transferred to adenosylcobalamin. Other derivatives of the cobalamin such as aquo (hydroxy)- and cyanocobalamin did not mediate the methyl transfer reaction. The dehydrogenation and methyl transfer reactions were assumed to occur concomitantly, and the methyl transfer reaction seemed to depend on the dehydrogenation. To our knowledge, the enzyme is the first dehydrogenase that shows a methyl transfer activity as well. (+info)Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. (4/379)
Strain DCL14, which is able to grow on limonene as a sole source of carbon and energy, was isolated from a freshwater sediment sample. This organism was identified as a strain of Rhodococcus erythropolis by chemotaxonomic and genetic studies. R. erythropolis DCL14 also assimilated the terpenes limonene-1,2-epoxide, limonene-1,2-diol, carveol, carvone, and (-)-menthol, while perillyl alcohol was not utilized as a carbon and energy source. Induction tests with cells grown on limonene revealed that the oxygen consumption rates with limonene-1,2-epoxide, limonene-1,2-diol, 1-hydroxy-2-oxolimonene, and carveol were high. Limonene-induced cells of R. erythropolis DCL14 contained the following four novel enzymatic activities involved in the limonene degradation pathway of this microorganism: a flavin adenine dinucleotide- and NADH-dependent limonene 1, 2-monooxygenase activity, a cofactor-independent limonene-1, 2-epoxide hydrolase activity, a dichlorophenolindophenol-dependent limonene-1,2-diol dehydrogenase activity, and an NADPH-dependent 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity. Product accumulation studies showed that (1S,2S,4R)-limonene-1,2-diol, (1S, 4R)-1-hydroxy-2-oxolimonene, and (3R)-3-isopropenyl-6-oxoheptanoate were intermediates in the (4R)-limonene degradation pathway. The opposite enantiomers [(1R,2R,4S)-limonene-1,2-diol, (1R, 4S)-1-hydroxy-2-oxolimonene, and (3S)-3-isopropenyl-6-oxoheptanoate] were found in the (4S)-limonene degradation pathway, while accumulation of (1R,2S,4S)-limonene-1,2-diol from (4S)-limonene was also observed. These results show that R. erythropolis DCL14 metabolizes both enantiomers of limonene via a novel degradation pathway that starts with epoxidation at the 1,2 double bond forming limonene-1,2-epoxide. This epoxide is subsequently converted to limonene-1,2-diol, 1-hydroxy-2-oxolimonene, and 7-hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone. This lactone spontaneously rearranges to form 3-isopropenyl-6-oxoheptanoate. In the presence of coenzyme A and ATP this acid is converted further, and this finding, together with the high levels of isocitrate lyase activity in extracts of limonene-grown cells, suggests that further degradation takes place via the beta-oxidation pathway. (+info)Olfactory discrimination ability of human subjects for ten pairs of enantiomers. (5/379)
We tested the ability of human subjects to distinguish between enantiomers, i.e. odorants which are identical except for chirality. In a forced-choice triangular test procedure 20 subjects were repeatedly presented with 10 enantiomeric odor pairs and asked to identify the bottle containing the odd stimulus. We found (i) that as a group, the subjects were only able to significantly discriminate the optical isomers of alpha-pinene, carvone and limonene, whereas they failed to distinguish between the (+)- and (-)-forms of menthol, fenchone, rose oxide, camphor, alpha-terpineol, beta-citronellol and 2-butanol; (ii) marked individual differences in discrimination performance, ranging from subjects who were able to significantly discriminate between 6 of the 10 odor pairs to subjects who failed to do so with 9 of the 10 tasks; (iii) that with none of the 10 odor pairs were the antipodes reported to differ significantly in subjective intensity when presented at equal concentrations; and (iv) that error rates were quite stable and did not differ significantly between sessions, and thus, we observed a lack of learning or training effects. Additional tests of the degree of trigeminality and threshold measurements of the optical isomers of alpha-pinene, carvone and limonene suggest that the discriminability of these three enantiomeric odor pairs is indeed due to differences in odor quality. These findings support the assumption that enantioselective molecular odor receptors may only exist for some but not all volatile enantiomers and thus that chiral recognition of odorants may not be a general phenomenon but is restricted to some substances. (+info)Odor response properties of rat olfactory receptor neurons. (6/379)
Molecular biology studies of olfaction have identified a multigene family of molecular receptors that are likely to be involved in odor transduction mechanisms. However, because previous functional data on peripheral coding were mainly collected from inferior vertebrates, it has been difficult to document the degree of specificity of odor interaction mechanisms. As a matter of fact, studies of the functional expression of olfactory receptors have not demonstrated the low or high specificity of olfactory receptors. In this study, the selectivity of olfactory receptor neurons was investigated in the rat at the cellular level under physiological conditions by unitary extracellular recordings. Individual olfactory receptor neurons were broadly responsive to qualitatively distinct odor compounds. We conclude that peripheral coding is based on activated arrays of olfactory receptor cells with overlapping tuning profiles. (+info)Biosynthesis of bitter acids in hops. A (13)C-NMR and (2)H-NMR study on the building blocks of humulone. (7/379)
The biosynthesis of humulone, an antibacterial bitter acid from hops, was studied by isotope-incorporation experiments using (13)C-labelled glucose or (2)H(2)O. (13)C enrichments, (2)H enrichments and (13)C(13)C coupling patterns identify isovaleryl-CoA, malonyl-CoA and dimethylallyl pyrophosphate as precursors for humulone. Dimethylallyl pyrophosphate, which serves as a building block for the bitter acid, is generated via the deoxyxylulose pathway of terpenoid biosynthesis. The data confirm that a symmetrical intermediate is involved in humulone formation. (+info)Induction by adozelesin and hydroxyurea of origin recognition complex-dependent DNA damage and DNA replication checkpoints in Saccharomyces cerevisiae. (8/379)
DNA damaging agents induce a conserved intra-S-phase checkpoint that inhibits DNA replication in eukaryotic cells. To better understand this checkpoint and its role in determining the efficacy of antitumor drugs that damage DNA, we examined the effects of adozelesin, a DNA-alkylating antitumor agent that has a profound inhibitory effect on initiation of DNA replication in mammals, on the replication of Saccharomyces cerevisiae chromosomes. Adozelesin inhibited initiation of S. cerevisiae DNA replication by inducing an intra-S-phase DNA damage checkpoint. This inhibitory effect was abrogated in orc2-1 cells containing a temperature-sensitive mutation in a component of the origin recognition complex (ORC) that also causes a defect in initiation. The orc2-1 mutation also caused a defect in a checkpoint that regulates the activation of origins in late S phase in cells treated with hydroxyurea. Defects in both initiation and checkpoint regulation in the orc2-1 strain were suppressed by deletion of a gene encoding a putative acetyltransferase, SAS2. Adozelesin also induced a cellular response that requires a function of ORC in G(1). A similar G(1)-specific response in mammals may contribute to the cytotoxic and antitumor properties of this and other DNA-damaging drugs. (+info)
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Cyclohexene
... is not very stable upon long term storage with exposure to light and air because it forms peroxides. Cyclohexene is ... Safety Data Sheet for cyclohexene Safety MSDS data Reaction of Cyclohexene with Bromine and Potassium Permanganate Cyclohexene ... Cyclohexene is a hydrocarbon with the formula C6H10. This cycloalkene is a colorless liquid with a sharp smell. It is an ... Cyclohexene is most stable in a half-chair conformation, unlike the preference for a chair form of cyclohexane. One basis for ...
Cyclohexene oxide
It can react in cationic polymerization to poly(cyclohexene oxide). As cyclohexene is monovalent, poly(cyclohexene oxide) is a ... Cyclohexene oxide is produced in epoxidation reaction from cyclohexene. The epoxidation can take place either in a homogeneous ... In laboratory, cyclohexene oxide can also be prepared by reacting cyclohexene with magnesium monoperoxyphthalate (MMPP) in a ... Cyclohexene has been studied extensively by analytical methods. Cyclohexene oxide can be polymerized in solution, catalyzed by ...
2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
Common names for the enzyme are: MenD SEPHCHC synthase 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid ...
Elimination reaction
E1cB-elimination reaction Coleman, G. H.; Johnstone, H. F. (1925). "Cyclohexene". Organic Syntheses. 5: 33. doi:10.15227/orgsyn ...
Cyclohexanol
Heating in the presence of acid catalysts converts cyclohexanol to cyclohexene. Cyclohexanol has at least two solid phases. One ... G. H. Coleman, H. F. Johnstone (1925). "Cyclohexene". Organic Syntheses. 5: 33. doi:10.15227/orgsyn.005.0033. CDC - NIOSH ...
Mass spectral interpretation
Cyclohexenes often undergo retro Diels-Alder reactions. Similar to alkenes, alkynes often show strong molecular ion peak. ... This reaction occurs mainly in cyclohexene and its derivatives. Upon ionization, the pi electrons are excited and generate a ...
Cyanamide
doi:10.1002/anie.197308411.. S. Hünig, E. Lücke, and W. Brenninger (1961). "1-Morpholino-1-Cyclohexene". Organic Syntheses: 65 ...
Retro-Diels-Alder reaction
It involves the formation of a diene and dienophile from a cyclohexene. It can be accomplished spontaneously with heat, or with ... For instance, the cleavage of cyclohexene to give butadiene and ethene has been observed, but only at temperatures exceeding ... Uchiyama, Masao; Tomioka, Tadao; Amano, Akira (2002-05-01). "Thermal Decomposition of Cyclohexene". The Journal of Physical ... providing diene and dienophile from starting cyclohexene derivatives. As early as 1929, this process was known and applied to ...
Norbornene
The molecule consists of a cyclohexene ring with a methylene bridge between carbons 1 and 4. The molecule carries a double bond ... "2-Cyclohexene-1,4-dione". Organic Syntheses.; Collective Volume, vol. 9, p. 186 Thansandote, Praew; Chong, Eugene; Feldmann, ...
1,4-Benzoquinone
Oda, M.; Kawase, T.; Okada, T.; Enomoto, T. (1996). "2-Cyclohexene-1,4-dione". Organic Syntheses. 73: 253. doi:10.15227/orgsyn. ...
Rhodoplanes
Q. Ashton Acton (2013). Cyclohexenes-Advances in Research and Application: 2013 Edition: ScholarlyBrief. ScholarlyEditions. ...
Orange (fruit)
1-methyl-4-(1-methylvinyl)cyclohexene". ECHA. January 2019. Wikiquote has quotations related to Oranges. Look up orange (fruit ...
Cyclohexanecarboxylic acid
It can also be oxidized to cyclohexene. Cyclohexanecarboxylic acid exhibits the reactions typical of carboxylic acids, ...
Methylcyclohexene
The poor selectivity is due to the migration of the double bond in the cyclohexene ring. Reaction with dichloromethylsilane is ... Khan, M. M. T.; Rao, A. P.; Bhatt, S. D.; Merchant, R. R. (1990). "Epoxidation of cyclohexene, methylcyclohexene and cis- ... The location of the methyl group relative to the cyclohexene double bond creates the three different structural isomers. These ... Methylcyclohexene refers to any one of three organic compounds consisting of cyclohexene with a methyl group substituent. ...
Cyclohexa-1,3-diene
1,4-Cyclohexadiene Cyclohexene Schaefer, John P.; Endres, Leland (1967). "1,3-Cyclohexadiene". Organic Syntheses. 47: 31. doi: ...
W. Dean Harman
Preparation of cyclohexene isotopologues and stereoisotopomers from benzene. Nature, 581(7808), 288-293. Wilde, J. H., Myers, J ... He is the first to demonstrate the step by step conversion of benzene to cyclohexene with varying degrees of deuterium ... "Preparation of cyclohexene isotopologues and stereoisotopomers from benzene". Nature. 581 (7808): 288-293. Bibcode:2020Natur. ...
Hydrogenation
Similarly, the cyclohexene is ordinarily reduced to cyclohexane. In many homogeneous hydrogenation processes, the metal binds ...
Ozonolysis
Claus, Ronald E.; Schreiber, Stuart L. (1986). "Ozonolytic Cleavage of Cyclohexene to Terminally Differentiated Products". 64: ...
Pinnatoxin
The structure of pinnatoxin is composed of a cyclic imine (A ring) spirolinked to a cyclohexene ring (G ring), a dispiro 6,5,6 ... Ion channel toxins, Neurotoxins, Invertebrate toxins, Cyclohexenes, Azepines, Spiro compounds, Tetrahydropyrans, ...
Diels-Alder reaction
... because the cyclohexene product bears substituents in positions that are analogous to the ortho and para positions of ... on those same carbons with respect to the cyclohexene ring. Likewise, cis,cis- and trans,trans-disubstitued dienes give cis ... to form a substituted cyclohexene derivative. It is the prototypical example of a pericyclic reaction with a concerted ... "How Lewis Acids Catalyze Ring-Openings of Cyclohexene Oxide". The Journal of Organic Chemistry. 86 (4): 3565-3573. doi:10.1021/ ...
Lewis acid catalysis
"How Lewis Acids Catalyze Ring-Openings of Cyclohexene Oxide". The Journal of Organic Chemistry. 86 (4): 3565-3573. doi:10.1021/ ...
Peroxymonophosphoric acid
Less stable epoxides are cleaved or react further; cyclohexene, styrene, and α-methylstyrene yield no isolable epoxides. In the ...
Fürst-Plattner Rule
... describes the stereoselective addition of nucleophiles to cyclohexene derivatives. Cyclohexene derivatives, such as imines, ... Epoxidation of a substituted cyclohexene affords a product where the R group resides in the pseudo-equatorial position. ... "How Lewis Acids Catalyze Ring-Openings of Cyclohexene Oxide". The Journal of Organic Chemistry. 86 (4): 3565-3573. doi:10.1021/ ...
Oxymercuration reaction
Pasto, D. J.; Gontarz, J. A. "Studies on the Mechanism of the Oxymercuration of Substituted Cyclohexenes". Journal of the ... below is an example of regioselectivity and stereospecificity of the oxymercuration reaction with substituted cyclohexenes. A ...
Meta-Chloroperoxybenzoic acid
The following scheme shows the epoxidation of cyclohexene with mCPBA. The epoxidation mechanism is concerted: the cis or trans ...
Polyol
"Rigid Hyperbranched Polycarbonate Polyols from CO2 and Cyclohexene-Based Epoxides". Macromolecules. 50 (16): 6088-6097. doi: ...
Bromocyclohexane
In principle, another synthesis involves addition of HBr to cyclohexene. http://web.pdx.edu/~wamserc/C334F99/Fans.htm ...
Xeno nucleic acid
With cyclohexene nucleic acid, research has shown that CeNAs with stereochemistry similar to the D form can create stable ... Gu P, Schepers G, Rozenski J, Van Aerschot A, Herdewijn P (2003). "Base pairing properties of D- and L-cyclohexene nucleic ... Types of synthetic XNA created so far include: 1,5-anhydrohexitol nucleic acid (HNA) Cyclohexene nucleic acid (CeNA) Threose ...
Menitrazepam
"A spectrophotometric and polarographic investigation of three new cyclohexene-substituted benzodiazepines". Talanta. 25 (4): ...
Adipic acid
1, p. 560 Sato, K.; Aoki, M.; Noyori, R. (1998). "A "Green" route to adipic acid: direct oxidation of cyclohexenes with 30 ... 4CO2H Another method is oxidative cleavage of cyclohexene using hydrogen peroxide. The waste product is water. Historically, ...
CDC - NIOSH Pocket Guide to Chemical Hazards -
Vinyl cyclohexene dioxide
2-Cyclohexene-1-carbonitrile
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Ruthenium(III) Based Diimine Complexes; Synthesis, Characterization, PXRD Study and Catalytic Hydrogenation of Cyclohexene |...
The newly synthesized ruthenium(III) diimines were tested as catalysts for hydrogenation of cyclohexene. The effect of the ... Ruthenium(III) Based Diimine Complexes; Synthesis, Characterization, PXRD Study and Catalytic Hydrogenation of Cyclohexene ... Scheme II: Catalytic cycle for the hydrogenation of cyclohexene by using [RuLnClH2O] ... complexes are promising precatalysts that have successfully catalyzed hydrogenation of cyclohexene by hydrogen gas under ...
Zinc glutarate as catalyst for the copolymerization of cyclohexene oxide and carbon dioxide
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The chemical named Cyclohexene, is a colorless, but very pungent liquid. It was being used in an experiment about whether polar ... Cyclohexene causes Classroom Disruption. February 21, 2013. by lpahomov Leave a Comment ... VK said, "If we had spilled 350,000 times as much [cyclohexene], we would have still been within OSHA regulated limits to stay ...
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Methyl 1-cyclohexene-1-carboxylate,CAS 18448-47-0
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Dehydrogenation of cyclohexene on ordered Sn/Pt(111) surface alloys<...
The di-σ bonded cyclohexene on the Pt(111) surface is changed to hydrogen-bonded cyclohexene on the (√3 × √3)R30°Sn / Pt(111) ... At higher cyclohexene coverages, the self-poisoning of the surface by cyclohexene or reaction intermediates becomes the ... The di-σ bonded cyclohexene on the Pt(111) surface is changed to hydrogen-bonded cyclohexene on the (√3 × √3)R30°Sn / Pt(111) ... At higher cyclohexene coverages, the self-poisoning of the surface by cyclohexene or reaction intermediates becomes the ...
Investigation of cyclohexene thermal decomposition and cyclohexene + OH reactions<...
title = "Investigation of cyclohexene thermal decomposition and cyclohexene + OH reactions",. abstract = "Cyclohexene is a ... Investigation of cyclohexene thermal decomposition and cyclohexene + OH reactions. Combustion and Flame. 2022 Oct 25;112437. ... Investigation of cyclohexene thermal decomposition and cyclohexene + OH reactions. In: Combustion and Flame. 2022 ; pp. 112437. ... Investigation of cyclohexene thermal decomposition and cyclohexene + OH reactions. / Liu, Dapeng; Farooq, Aamir. ...
Elimination reaction - Wikipedia
RCSB PDB - ADN Ligand Summary Page
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde - Hydroxyisohexyl 3-cyclohexene carboxaldehyde - Cosmetic ingredients -...
Hydroxyisohexyl 3 cyclohexene carboxaldehyde , Hydroxyisohexyl-3 cyclohexene carboxaldehyde , Hydroxyisohexyl 3-cyclohexene ... Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. Inci name. Hydroxyisohexyl 3-cyclohexene carboxaldehyde. French name. ... Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. CAS number.. 31906-04-4 / 51414-25-6. EC number.. 250-863-4 / 257-187-9. Other ... carboxaldehyde , Hydroxyisohexyl-3-cyclohexene carboxaldehyde , Hydroxyisohexyl 3-cyclo-hexene carboxaldehyde , Lyral , ...
Peroxide Forming Chemicals - Environmental Health and Safety | University of South Carolina
NIOSHTIC-2 Search Results - Full View
Ring-opening polymerization of cyclohexene oxide using aluminum amine-phenolate complexes - Memorial University Research...
Kerton, Francesca M. and Plommer, Hart and Reim, Immanuel (2015) Ring-opening polymerization of cyclohexene oxide using ... Ring-opening polymerization of cyclohexene oxide using aluminum amine-phenolate complexes. Ring-opening polymerization of ... Remarkably active (down to 0.001% Al) catalysts for ring-opening polymerization of cyclohexene oxide under neat reaction ...
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Cyclohexanol - Wikipedia
CFR - Code of Federal Regulations Title 21
1-(1-Piperidino)cyclohexene CAS 2981-10-4 - Caming Pharmaceutical Ltd - Focusing on development of pharmaceutical-related...
... cyclohexene CAS 2981-10-4 provided by Caming Pharmaceutical Ltd - who focuses on development of pharmaceutical-related ... Home / Products / Pharmaceutical Chemicals / Intermediates / 1-(1-Piperidino)cyclohexene CAS 2981-10-4 ... 1-(1-Piperidino)cyclohexene CAS 2981-10-4. In Intermediates, Pharmaceutical Chemicals, Products ... http://watson-int.com/1-(1-Piperidino)cyclohexene-cas-2981-10-4/ ...
AtJims - INCI - Ricinus communis seed oil, olea europaea fruit oil, parfum, benzyl alcohol, coumarin, hydroxyisohexyl 3...
... hydroxyisohexyl 3-cyclohexene carboxaldehyde, limonene, linalool.. Pánsky eshop ponúkajúci prípravky na bradu, produkty na ... INCI - Ricinus communis seed oil, olea europaea fruit oil, parfum, benzyl alcohol, coumarin, hydroxyisohexyl 3-cyclohexene ... Ricinus communis seed oil, olea europaea fruit oil, parfum, benzyl alcohol, coumarin, hydroxyisohexyl 3-cyclohexene ... Ricinus communis seed oil, olea europaea fruit oil, parfum, benzyl alcohol, coumarin, hydroxyisohexyl 3-cyclohexene ...
Immersion calorimetry as a tool to evaluate the catalytic performance of titanosilicate materials in the epoxidation of...
The coordinatively saturated vanadium MIL-47 as a low leaching heterogeneous catalyst in the oxidation of cyclohexene | Center...
The coordinatively saturated vanadium MIL-47 as a low leaching heterogeneous catalyst in the oxidation of cyclohexene. K. Leus ... is evaluated as a catalyst in the epoxidation of cyclohexene. Different solvents and conditions are tested and compared. If the ... and also radical pathways are prominently operative leading to the formation of an adduct between the peroxide and cyclohexene ...
Oxidation of cyclohexeneHydrogenation of cyclohexeneOxideEpoxidationCyclohexaneCatalystsCarboxylicReactionDiepoxideButadieneSynthesisReactionsAbstractCompoundsChemicalConditionsTimesCarboxaldehydeLimoneneCyclohexaneDerivativeEpoxidationAminoBenzeneToxicityEnantiomerMolecularLiquidVersusHeptaneAcidStudyProductFormFormation
Oxidation of cyclohexene2
- The product is commercially manufactured by Birch reduction of phenol or anisole, alternatively by catalytic oxidation of cyclohexene. (exsyncorp.com)
- We also report that C−H bond activation is preferred over C=C epoxidation in the oxidation of cyclohexene by the nonheme high-spin (HS) and intermediate-spin (IS) iron(IV)-oxo complexes, whereas the C=C double bond epoxidation becomes a preferred pathway in the oxidation of deuterated cyclohexene by the nonheme HS and IS iron(IV)-oxo complexes. (ewha.ac.kr)
Hydrogenation of cyclohexene2
- The newly synthesized ruthenium(III) diimines were tested as catalysts for hydrogenation of cyclohexene. (researchsquare.com)
- Catalytic experiments reported that the ongoing ruthenium(III) complexes are promising precatalysts that have successfully catalyzed hydrogenation of cyclohexene by hydrogen gas under moderate process conditions. (researchsquare.com)
Oxide2
Epoxidation2
- Different types of titanosilicates are synthesized, structurally characterized, and subsequently catalytically tested in the liquid-phase epoxidation of cyclohexene. (uantwerpen.be)
- Indirect measurement of peracetic acid was achieved by desorption from the sorbent and subsequent treatment with cyclohexene to initiate an epoxidation reaction, formally known as the Prilezhaev reaction. (cdc.gov)
Cyclohexane2
- The adsorption and dehydrogenation of cyclohexene on Pt(111) and two Sn/Pt(111) surface alloys has been studied since cyclohexene is a likely intermediate in the dehydrogenation of cyclohexane to benzene, a prototypical reaction for catalytic reforming. (princeton.edu)
- Cyclohexene is a common intermediate in the oxidation of cyclohexane and alkyl-substituted cyclohexanes. (edu.sa)
Catalysts1
- Heating in the presence of acid catalysts converts cyclohexanol to cyclohexene . (wikipedia.org)
Carboxylic1
- Oseltamivir phosphate, (3R,4R,5S)-4-acetylamino-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1- carboxylic acid, ethyl ester, phosphate (1:1) is pro-drug of the active metabolite, oseltamivir carboxylate. (who.int)
Reaction5
- At higher cyclohexene coverages, the self-poisoning of the surface by cyclohexene or reaction intermediates becomes the determining factor in the reactions of cyclohexene and the addition of Sn to the surface only slightly increases the selectivity of gas phase benzene production. (princeton.edu)
- We conducted rate coefficient measurements of cyclohexene + OH reaction (k1) over 933-1259 K and 1-4 bar using a narrow-linewidth UV absorption diagnostic of OH radicals near 306.67 nm. (edu.sa)
- Our rate values may be fitted with a two-parameter Arrhenius expression (units of cm3molecule−1s−1): k1 = 1.28 × 10−10 e( −1225/T ) We also investigated channel-specific competition in OH + cyclohexene reaction. (edu.sa)
- We studied cyclohexene thermal decomposition reaction (k2) by tracing the product 1,3-butadiene near 212.5 nm over 1092-1361 K and 0.82-1 bar. (edu.sa)
- Compared to literature works, our highly sensitive UV diagnostic of 1,3-butadiene enabled time-resolved measurements with low cyclohexene concentration, which guaranteed nearly isothermal conditions despite reaction endothermcity. (edu.sa)
Diepoxide1
- 3. Ideisan I. Abu-Abdoun "Polymerization of 4-Vinyl-1-Cyclohexene Diepoxide by Rhenium Carbonyl Compounds" Academic journal of Polymer Science. (sharjah.ac.ae)
Butadiene1
- Our measured rate coefficients may be expressed as (unit of s−1): k2 = 3.68 × 1014e( −31,562/T ) We implemented our determined rate coefficients (k1 and k2) in a literature cyclohexene kinetic model and also updated the 1,3-butadiene sub-mechanism. (edu.sa)
Synthesis1
- 2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. (exsyncorp.com)
Reactions2
Abstract1
- abstract = "Stereoselectivity in photocycloaddition of bicyclic enones 1,2, 5, and 6 to 2-butene and cyclohexene is discussed. (nycu.edu.tw)
Compounds1
- Among the ten, five compounds are specific to males namely, 3-cyclohexene-1-methanol (I), 3-amino-s-triazole (II), 4-ethyl phenol (III), 3-ethyl-2,7-dimethyl octane (IV) and 1-iodoundecane (V). The compound, 4-ethylphenol, has been previously reported in several strains of male mice. (who.int)
Chemical1
- The chemical named Cyclohexene, is a colorless, but very pungent liquid. (slamedia.org)
Conditions1
- At small cyclohexene coverages, the alloying of Pt with Sn increases both the activity and selectivity of gas phase benzene production under UHV conditions. (princeton.edu)
Times2
- Mr. VK said, "If we had spilled 350,000 times as much [cyclohexene], we would have still been within OSHA regulated limits to stay in the room for 8 hours. (slamedia.org)
- The updated model shows improved predictions of measured ignition delay times of cyclohexene. (edu.sa)
Carboxaldehyde1
- Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is the most important sensitizer of the 6 fragrance materials included in FM II. (kb.se)
Limonene1
- The focus here is on a simple organic molecule, ( R )-(+)-4- and ( S )-(-)-4-isopropenyl-1-methyl-1-cyclohexene (the two enantiomers of limonene), which is safe, easy to find, and of real-world and industrial interest. (scienceinschool.org)
Cyclohexane5
- Because very little data are available concerning the effects produced by acute inhalation exposure to cyclohexene, the chosen IDLH is based on an analogy with cyclohexane which has an IDLH of 10,000 ppm. (cdc.gov)
- VLE and LLE Dataset for the System Cyclohexane + Cyclohexene + Water + Cyclohexanol + Formic Acid + Formic Acid Cyclohexanol Ester. (mpg.de)
- VLE and LLE data for the system cyclohexane plus cyclohexene plus water plus cycloblexanol. (mpg.de)
- The gas-phase ozonolysis of cyclic- alkenes ( 1-methyl-cyclohexene , methylene - cyclohexane , α-pinene , β-pinene ) is studied with respect to the pressure dependent formation of secondary organic aerosol ( SOA ). (rsc.org)
- I believe the main impurity in commercial toluene is the corresponding methyl-cyclohexane and cyclohexenes, as their boiling points are close to that of toluene. (sciencemadness.org)
Derivative2
- 13. The cyclohexene derivative MC-3129 exhibits antileukemic activity via RhoA/ROCK1/PTEN/PI3K/Akt pathway-mediated mitochondrial translocation of cofilin. (nih.gov)
- They then methylated the amine, did a particularly nice RCM with Grubbs II, and removed the auxiluary to leave the desired enantiomer of the amino cyclohexene derivative in high e.e. and yield. (organic-chemistry.org)
Epoxidation2
- Their catalytic activities in the cyclohexene epoxidation with TBHP as oxidant and heptane as solvent were also examined. (ensicaen.fr)
- The results were acquired through Gas Chromatography Mass Spectrometry (GCMS), which showed no epoxidation of cyclohexene but did show significant reduction of cyclohexene peak area, as compared to chlorobenzene, internal standard. (owu.edu)
Amino1
- Oseltamivir phosphate, (3R,4R,5S)-4-acetylamino-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1- carboxylic acid, ethyl ester, phosphate (1:1) is pro-drug of the active metabolite, oseltamivir carboxylate. (who.int)
Benzene2
- Environmental sampling revealed that the employees were not exposed to toxic concentrations of styrene (100425), butadiene (106990), vinyl-cyclohexene (100403), toluene (108883), dimethylpyridine (108485), cyclooctadiene, benzene (71432) and vinyl-pyridine (1337811). (cdc.gov)
- Problems with Kekule's structure were first hinted at when it became apparent that the enthalpy of hydrogenation of benzene (-208 kJ mol -1 ) was found not to be three times the value found for cyclohexene (-121 kJ mol -1 ) with its one C=C bond. (bris.ac.uk)
Toxicity2
Enantiomer1
- Pt(II) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism. (upol.cz)
Molecular1
- The Au-SH-bearing catalyst is inactive for cyclohexene oxidation with molecular oxygen in liquid phase, but those having sulfonic groups are active and selective for its allylic oxidation. (csic.es)
Liquid2
- Peng, C.T., Structure assignment by retention index in gas-liquid radiochromatography of substituted cyclohexenes, J. Chromatogr. (chemspider.com)
- We characterized a liquid system, consisting of 1-phenyl-1-cyclohexene and deionized water, using both lens and prism devices. (nih.gov)
Versus1
- Photoswitching Behavior of a Cyclohexene-Bridged versus a Cyclopentene-Bridged Dithienylethene System. (sigmaaldrich.com)
Heptane1
- The molecule cyclohexene was to be oxidized to form 7-oxabicyclo[4,1,0]heptane involving hydrogen peroxide as the oxidant at different conditions. (owu.edu)
Acid2
Study1
- The results section reports a range of non-selective hydrogenation reactions, commencing with a detailed study of the hydrogenation of cyclohexene which was used to explore the capabilities of the equipment. (bl.uk)
Product1
- And that would give us our product on the right over here, which is a cyclohexene ring. (khanacademy.org)
Form2
- And then finally, the electrons in magenta right here, on the diene, move down to here to form the double bond and to give us our cyclohexene ring. (khanacademy.org)
- If we think about electron density flowing from the diene to the dienophile, I can move these electrons into here so we form a bond between these two carbons, and these electrons move into here to form a bond between these two carbons, and then these electrons down to give us our cyclohexene ring. (khanacademy.org)
Formation1
- The suppression coincides with the formation of ketene ( α-pinene , 1-methyl-cyclohexene ), ethene ( 1-methyl-cyclohexene ) and the increased formation of CO (all alkenes ) at lower reaction pressures. (rsc.org)