The preparation of new phosphorus-centered functional groups for modified oligonucleotides and other natural phosphates. (1/10)

Efforts to develop synthetic methodologies allowing the preparation of alpha,alpha- difluorophosphonothioates, alpha,alpha-difluorophosphonodithioates, alpha,alpha-difluorophosphono- trithioates, and alpha,alpha-difluorophosphinates are reviewed in the light of applications in the field of modified oligonucleotides and cyclitol phosphates. Two successful approaches have been developed, based either on the addition of phosphorus-centered radicals onto gem-difluoroalkenes or on a process involving the addition of lithiodifluorophosphono- thioates 91 onto a ketone and the subsequent deoxygenation reaction of the adduct. The radical route successfully developed a practical route to alpha,alpha-difluoro-H-phosphinates which proved to be useful intermediates to a variety of phosphate isosters. The ionic route led to the first preparation of phosphonodifluoromethyl analogues of nucleoside- 3'-phosphates.  (+info)

Hypoglycemic effect of 13-membered ring thiocyclitol, a novel alpha-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata). (2/10)

A novel 13-membered ring thiocyclitol, isolated from an aqueous extract of Kothala-himbutu (Salacia reticulata), inhibited alpha-glucosidase in vitro. The inhibitory activity was investigated by maltose- and sucrose-loading on Wistar rats. This study found significant lowering of postprandial glucose levels, and the potency of 13-membered ring thiocyclitol was confirmed in vivo.  (+info)

Progress in aminocyclitol biosynthesis. (3/10)

 (+info)

Concise synthesis of iminocyclitols via Petasis-type aminocyclization. (4/10)

 (+info)

Synthesis of structurally simplified analogues of pancratistatin: truncation of the cyclitol ring. (5/10)

 (+info)

Biosynthesis of the aminocyclitol subunit of hygromycin A in Streptomyces hygroscopicus NRRL 2388. (6/10)

 (+info)

Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. (7/10)

 (+info)

Regioselectivity in the ring opening of epoxides for the synthesis of aminocyclitols from D-(-)-quinic acid. (8/10)

 (+info)

Rapamycin and process of preparation - Ayerst McKenna and Harrison Ltd.Rapamycin and process of preparation - Ayerst McKenna and Harrison Ltd.
Antibiotic rapamycin is producible by culturing Streptomyces hygroscopicus NRRL 5491 in an aqueous nutrient medium. Rapamycin has antifungal properties. Methods for its preparation and use are disclos
https://www.freepatentsonline.com/3993749.html
L-lizinska ciklodeaminaza - Википедија, слободна енциклопедијаL-lizinska ciklodeaminaza - Википедија, слободна енциклопедија
Khaw, L.E., Bohm, G.A., Metcalfe, S., Staunton, J. and Leadlay, P.F. (1998). „Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase. J. Bacteriol. 180: 809-814. PMID 9473033 ...
https://sr.wikipedia.org/wiki/L-lizinska_ciklodeaminaza
RCSB PDB - 3VDN: Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP Macromolecule...RCSB PDB - 3VDN: Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP Macromolecule...
3VDN: Crystal Structure of the VldE, the pseudo-glycosyltransferase, which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis
http://www.rcsb.org/pdb/explore/derivedData.do?structureId=3VDN
Export Data and Price of Salacia Reticulata | www.eximpulse.comExport Data and Price of Salacia Reticulata | www.eximpulse.com
Export Data And Price Of Salacia Reticulata , www.eximpulse.com Eximpulse Services is the place where you can find the recent and updated Trade intelligence report of Salacia Reticulata Export Data. Whole information is based on updated Export shipment data of Indian Customs. All the compilation is done on the basis of All India ports data and has been done on daily basis. This helps you to get all India Salacia Reticulata Export data. You can find previous two days Salacia Reticulata Export data on Eximpulse Services. Salacia Reticulata Export data can be useful in different kind of analysis such as: Export price, Quantity, market scenarios, Price trends, Duty optimization and many more. Some Sample Shipment records for Salacia Reticulata Export Data of India are mentioned above. Further for Free sample and pricing of detailed reports contact on [email protected] Data post 2012 as per Notification No.18/2012 - Customs(N.T.) and does not have names of Indian companies and Foreign ...
https://www.eximpulse.com/export-product-Salacia-Reticulata.htm
Salacia Oblonga / Salacia Reticulata - Buy Salacia Diabetes Product on Alibaba.comSalacia Oblonga / Salacia Reticulata - Buy Salacia Diabetes Product on Alibaba.com
Salacia Oblonga / Salacia Reticulata , Find Complete Details about Salacia Oblonga / Salacia Reticulata,Salacia Diabetes from Slimming Tea Supplier or Manufacturer-H.BILAL & CO
http://www.alibaba.com/product-detail/Salacia-Oblonga-Salacia-Reticulata_10941888.html
US5529989A - Pancratistatin prodrug - Google PatentsUS5529989A - Pancratistatin prodrug - Google Patents
Pancratistatin has been selected for pre-clinical development but is sparingly soluble in water. A disodium phosphate derivative has been synthesized which is water soluble and is bioequivalent thereof. The critical step in the synthesis of the phenolic phosphate was phosphorylation of 1,2,3,4-tetraacetoxy-pancratistatin with dibenzyloxy(N,N-diisopropylamido)phosphine. This pancratistatin prodrug has the structure set forth below: ##STR1##
https://patents.google.com/patent/US5529989?oq=6016038
Orally administered Salacia reticulata extract reduces H1N1 influenza clinical symptoms in murine lung tissues putatively due...Orally administered Salacia reticulata extract reduces H1N1 influenza clinical symptoms in murine lung tissues putatively due...
TY - JOUR. T1 - Orally administered Salacia reticulata extract reduces H1N1 influenza clinical symptoms in murine lung tissues putatively due to enhanced natural killer cell activity. AU - Romero-Pérez, Gustavo A.. AU - Egashira, Masayo. AU - Harada, Yuri. AU - Tsuruta, Takeshi. AU - Oda, Yuriko. AU - Ueda, Fumitaka. AU - Tsukahara, Takamitsu. AU - Tsukamoto, Yasuhiro. AU - Inoue, Ryo. PY - 2016/3/31. Y1 - 2016/3/31. N2 - Influenza is a major cause of respiratory tract infection. Although most cases do not require further hospitalization, influenza periodically causes epidemics in humans that can potentially infect and kill millions of people. To countermeasure this threat, new vaccines need to be developed annually to match emerging influenza viral strains with increased resistance to existing vaccines. Thus, there is a need for finding and developing new anti-influenza viral agents as alternatives to current treatments. Here, we tested the antiviral effects of an extract from the stems and ...
https://okayama.pure.elsevier.com/en/publications/orally-administered-salacia-reticulata-extract-reduces-h1n1-influ
Plus itPlus it
One of the biggest hurdles in the fight against cancer is the non‐selective nature of most current treatments. On the other hand, opioids‐refractive cancer pain is a most important unsolved problem. Consequently, the search and development of new drugs that are tumor‐killing (while non‐cytotoxic to normal cells) and/or potent analgesics are major goals in cancer research. In this context, pancratistatin and tetrodotoxin, the most prominent representatives of two different families of natural products, have been identified as highly promising leads for cancer treatment and cancer pain, respectively; in fact, they are currently at the focus of some initiatives for pharmaceutical development.. Interest in pancratistatin stems from its high level of in vitro and in vivo cell growth inhibitory activity on a wide variety of human cancer cell lines, but particularly from its mode of action that, while yet unknown, is very selective: pancratistatin does not affect normal cells in clear contrast ...
http://mct.aacrjournals.org/content/8/12_Supplement/A176
Salacia reticulata - HerbochemSalacia reticulata - Herbochem
Disclaimer: This information on site is general information and are not evaluated by FDA (Food Drug Administration) . they are not intended to treat ,cure or prevent any disease ...
https://www.herbochem.com/salacia-reticulata/
KEGG ENZYME: 2.7.1.187KEGG ENZYME: 2.7.1.187
Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway ...
http://www.genome.jp/dbget-bin/www_bget?ec:2.7.1.187
Items where Author is Sum, Anita - Repository of the Academys LibraryItems where Author is Sum, Anita - Repository of the Academys Library
Sztaricskai, Ferenc and Batta, Gyula and Boda, Zoltán and Gunda, Tamás and Herczegh, Pál and Kobzos, Tibor and Lekli, István and Pelyvás Ferenczik, István and Sum, Anita and Tamaskó, Éva (2009) Glikopeptid és ciklitol antibiotikumok szintetikus módosítása, biológiai vizsgálata = Synthetic modification and biological investigation of glycopeptide and cyclitol antibiotics. Project Report. OTKA. ...
http://real.mtak.hu/view/creators/Sum=3AAnita=3A=3A.default.html
Fitness cost of chromosomal drug resistance-conferring mutations - Zurich Open Repository and ArchiveFitness cost of chromosomal drug resistance-conferring mutations - Zurich Open Repository and Archive
To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an in vitro competition assay with defined Mycobacterium smegmatis laboratory mutants; selected mutations were introduced by genetic techniques to address the possibility that compensatory mutations ameliorate the resistance cost. We found that the chromosomal drug resistance mutations studied often had only a small fitness cost; compensatory mutations were not involved in low-cost or no-cost resistance mutations. When drug resistance mutations found in clinical isolates were considered, selection of those mutations that have little or no fitness cost in the in vitro competition assay seems to occur. These results argue against expectations that link decreased levels of antibiotic consumption with the ...
http://www.zora.uzh.ch/id/eprint/4247/
US Patent Application for USE OF IMINOCYCLITOLS AS INHIBITORS OF BACTERIAL ADHERENCE TO EPITHELIAL CELLS Patent Application ...US Patent Application for USE OF IMINOCYCLITOLS AS INHIBITORS OF BACTERIAL ADHERENCE TO EPITHELIAL CELLS Patent Application ...
It comprises the use of D-fagomine or derivatives thereof in the prevention and/or coadjuvant treatment of bacterial infections, as well as to pharmaceutical, veterinary, or food and feed, pet food compositions containing them.
https://patents.justia.com/patent/20130011344
Items where Author is Boda, Zoltán - Repository of the Academys LibraryItems where Author is Boda, Zoltán - Repository of the Academys Library
Boda, Zoltán (2016) Teendők súlyos vérzés vagy sürgős sebészeti beavatkozás esetén direkt orális antikoaguláns gyógyszerrel kezeltekben. Az új dabigatran-antidótum: idarucizumab helye a klinikai gyakorlatban. Orvosi Hetilap, 157 (12). pp. 443-450. ISSN 0030-6002 Sztaricskai, Ferenc and Batta, Gyula and Boda, Zoltán and Gunda, Tamás and Herczegh, Pál and Kobzos, Tibor and Lekli, István and Pelyvás Ferenczik, István and Sum, Anita and Tamaskó, Éva (2009) Glikopeptid és ciklitol antibiotikumok szintetikus módosítása, biológiai vizsgálata = Synthetic modification and biological investigation of glycopeptide and cyclitol antibiotics. Project Report. OTKA. Muszbek, László and Bagoly, Zsuzsa and Bereczky, Zsuzsanna and Boda, Zoltán and Fazakas, Ferenc and Hársfalvi, Jolán and Hevessy, Zsuzsa and Katona, Éva and Kiss, Csongor and Komáromi, István and Losonczy, Gergely and Pfliegler, György and Schlammadinger, Ágota and Tóth, Judit and Varga, Sándor (2009) Ritka ...
http://real.mtak.hu/view/creators/Boda=3AZolt=E1n=3A=3A.default.html
Plus itPlus it
Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on preclinical models, including melanoma. Despite extensive investigations, pancratistatin or narciclasine analogues did not succeed to provide sufficient therapeutic benefit, [1] mostly hampered by poor water solubility and systemic toxicity [1]. To overcome those limitations, we developed a chemistry program aimed at improving both their physicochemical and pharmacological properties. A literature survey suggests that any structural modification of this highly oxigenated isocarbostiryl specific scaffold would lead to a loss of activity except on position 1, difficult to achieve but interesting to explore.. A series of 40 novel 1-aminopancratistatin derivatives was synthesised starting from large quantities of narciclasine extracted from Narcissus bulbs. These novel compounds exhibit an improved pharmaceutical profile facing standard solubility, plasmatic and microsomal ...
http://cancerres.aacrjournals.org/content/71/8_Supplement/3261
Lipophilic Curcumin Analogs And Methods Of Inhibiting HIV-1, Treating Latent HIV In The Brain, And Preventing HIV-Mediated...Lipophilic Curcumin Analogs And Methods Of Inhibiting HIV-1, Treating Latent HIV In The Brain, And Preventing HIV-Mediated...
1. A method for preventing HIV-mediated cognitive decline and HIV dementia, the method comprising administering to a subject infected with HIV a therapeutically effective amount of at least one compound of any of formulas (I) to (VIII), a pharmaceutically salt thereof, or combination thereof: ##STR00019## each X is independently selected from H, CH, or halogen (preferably the halogen is F), and n=1 to 5, wherein if n=1 a three membered ring is defined, if n=2 a four membered ring is defined, if n=3 a five membered ring is defined, if n=4 a six membered ring is defined and if n=5 a seven membered ring is defined, where carbons of the ring may include --CH or --CH2 and wherein the carbons of the ring optionally can be substituted with halogen or alkyl having 1 to 3 carbons ##STR00020## where X is O, NH, S, or CH2, and Y is O, NH, S, or CH2; ##STR00021## n=1 to 5, wherein if n=1 a three membered ring is defined, if n=2 a four membered ring is defined, if n=3 a five membered ring is defined, if n=4 ...
http://www.patentsencyclopedia.com/app/20140051742
SHJG 7765 - Oxidoreductase - Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) - SHJG 7765 gene & proteinSHJG 7765 - Oxidoreductase - Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) - SHJG 7765 gene & protein
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
http://www.uniprot.org/uniprot/H2JTF6
Streptomyces hygroscopicus, SEM - Stock Image C032/2295 - Science Photo LibraryStreptomyces hygroscopicus, SEM - Stock Image C032/2295 - Science Photo Library
Coloured scanning electron micrograph (SEM) of Streptomyces hygroscopicus, Gram-positive, aerobic, filamentous, biofilm-forming, rod prokaryote (bacterium). Streptomyces sp. belong to the Actinomycetes group and are bacteria that share many characteristics with the fungi. They grow usually as filaments (chains of cells) and often branch to form a network of filaments (mycelium) in the soil. These soil bacteria are responsible for the musty odour of soil. This strain of Streptomyces hygroscopicus produces the antibiotic, milbemycin, which is used as an insecticide and also to control certain parasitic infections in animals. It is also a biofilm forming bacterium. Biofilms are primarily accumulations of bacteria in aqueous environments. They form when bacteria secrete slimy, mucilaginous materials that provide the microorganisms with a means of attachment to moist surfaces. Magnification: x1,600 when shortest axis printed at 25 - Stock Image C032/2295
http://www.sciencephoto.com/media/799114/view
Synthesis of natural products utilizing ring cleavage reaction of myo-inositol derivatives<...Synthesis of natural products utilizing ring cleavage reaction of myo-inositol derivatives<...
TY - JOUR. T1 - Synthesis of natural products utilizing ring cleavage reaction of myo-inositol derivatives. AU - Chida, Noritaka. PY - 2000/7. Y1 - 2000/7. N2 - myo-Inositol, a cyclitol (cyclohexanepolyol) which is classified as a type of carbohydrates, occurs widely in nature and is known as a constituent of a secondary messenger in cells which stimulates the release of calcium from storage site. It is produced in large quantities from plants (rice bran and corn-steep liquors) by food industry. In spite of its abundance in nature and ready availability, myo-inositol has not been utilized widely as the starting material for the synthesis of natural products other than cyclitol derivatives. Given that regioselective ring cleavage of the cyclohexane ring in optically active and functionalized cyclitol derivatives is possible, myo-inositol is expected to be a potential precursor with stereochemical diversity for novel chiral building blocks in the synthesis of various natural products. In this ...
https://keio.pure.elsevier.com/en/publications/synthesis-of-natural-products-utilizing-ring-cleavage-reaction-of
RCSB PDB - Protein Feature View - Validoxylamine synthase - Q15JG1 (Q15JG1 STRHY)RCSB PDB - Protein Feature View - Validoxylamine synthase - Q15JG1 (Q15JG1 STRHY)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
http://www.rcsb.org/pdb/protein/Q15JG1
Dept. of Human Behavior, Ecology and Culture | ContactDept. of Human Behavior, Ecology and Culture | Contact
The Department of Human Behavior, Ecology and Culture investigates the role of culture in human evolution and adaptation. The evolution of fancy social learning in humans accounts for both the nature of human adaptation and the extraordinary scale and variety of human societies. The integration of ethnographic fieldwork with mathematical models and advanced quantitative methods is the departments methodological focus.
https://www.eva.mpg.de/ecology/contact.html?Fsize=0%252C%2B%40%2F%27A%3D0
Targeted Delivery of α-Galactosylceramide to CD8α+ Dendritic Cells Optimizes Type I NKT Cell-Based Antitumor Responses | The...Targeted Delivery of α-Galactosylceramide to CD8α+ Dendritic Cells Optimizes Type I NKT Cell-Based Antitumor Responses | The...
α-GalCer is a strong immunostimulatory molecule that holds great promise for antitumor therapeutic purposes and vaccine development (3, 7, 38). However, several concerns limit its use in clinics, including the uncontrolled response it promotes when delivered in a nonvectorized form. Cell-based antitumor therapy (transfer of DCs pulsed with α-GalCer) to better control iNKT cell functions is an attractive possibility (6, 7), although this procedure remains complex and expensive. Another strategy is to passively or actively deliver α-GalCer to DCs. We and others have shown that α-GalCer vectorized in PLGA-based NPs (30), silica particles (39), liposomes (40), or included into virus-like particles (41) activated iNKT cells but failed to prevent their hyporesponsiveness upon restimulation, a likely consequence of uncontrolled cell targeting. Therefore, a controlled delivery of α-GalCer is a requisite to optimize iNKT cell responses. A recent study showed that specific targeting of α-GalCer to ...
https://www.jimmunol.org/content/193/2/961
Salacia in Flora of China @ efloras.orgSalacia in Flora of China @ efloras.org
12. Salacia Linnaeus, Mant. Pl. 2: 159. 1771. 五层龙属 wu ceng long shu Authors: Hua Peng & Michele Funston Courondi Adanson.. Climbing or scrambling shrubs or small trees, glabrous or glabrescent; branchlets subterete, internode usually dilated or slightly flat. Leaves opposite to subopposite, rarely alternate, entire, crenate, or serrate, estipulate. Inflorescences axillary or cauliflorous, thyrsoid, cymose, or fasciculate. Flowers bisexual, 5-merous. Disk fleshy, pulvinate or cupular, entire or lobed, extrastaminal. Stamens (2 or)3; anthers longitudinally, obliquely, or transversely dehiscent, extrorse or apical. Ovary (2 or)3-locular, whole or mostly concealed in disk; ovules axile, 2-9 per locule. Berry spheroid, fleshy or subligneous. Seeds 2-12, angular, exalbuminous, surrounded by mucilaginous arils.. About 200 species: chiefly in tropical regions; ten species (eight endemic) in China.. ...
http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=129041
AcarboseAcarbose
Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of α-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes ...
https://www.toku-e.com/Acarbose-P4033.aspx
Making 8-membered rings - Its a DOS (diversity orientated synthesis) approach | Atlas of ScienceMaking 8-membered rings - Its a DOS (diversity orientated synthesis) approach | Atlas of Science
For many years, the primary method of global drug discovery has involved the synthesis of naturally occurring molecules and their derivatives. This drug discovery process would involve several steps, from initial extraction and isolation from a biological host, the molecule would then have to be cha...
http://atlasofscience.org/making-8-membered-rings-its-a-dos-diversity-orientated-synthesis-approach/
ElaiophylinElaiophylin
Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase. Elaiophylin is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and immunosuppressive activity and inhibits NO synthesis. Elaiophylin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumor cells ...
https://www.toku-e.com/Elaiophylin-P3104.aspx
organic chemistry - Ring expansion in cyclic compounds - Chemistry Stack Exchangeorganic chemistry - Ring expansion in cyclic compounds - Chemistry Stack Exchange
You overlooked the strain from the sp2 carbon in a small ring. The ring strain you have listed is based on sp3 carbon. sp2 supposed to have a planar triangular geometry (120°, compared to 109° for sp3) and will be more strained in a 3 or 4 membered ring. 6 membered ring will be best followed by 5 membered ring.. Also, you have discussed a lot about the stability of carboncations. Acid catalyzed elimination/rearrangement reaction is a thermodynamic condition. The stability of product is more important than the stability of intermediate.. ...
https://chemistry.stackexchange.com/questions/32822/ring-expansion-in-cyclic-compounds
GMD - Quinic acid, 3-caffeoyl-, cis- (6TMS) - InChI=1S/C34H66O9Si6/c1-44(2,3)38-27-21-19-26(23-28(27)39-45(4,5)6)20-22-31(35)37...GMD - Quinic acid, 3-caffeoyl-, cis- (6TMS) - InChI=1S/C34H66O9Si6/c1-44(2,3)38-27-21-19-26(23-28(27)39-45(4,5)6)20-22-31(35)37...
The Golm Metabolome Database (GMD) facilitates the search for and dissemination of mass spectra from biologically active metabolites quantified using GC-MS.
http://gmd.mpimp-golm.mpg.de/Analytes/5BB480FD-2D3A-4B4B-AD0F-7F689F761079.aspx
AC-11 Patents - OptigenexAC-11 Patents - Optigenex
The patent is a divisional of the application that issued as U.S. Patent No. 7,947,312. There are 16 claims directed to a method of enhancing immune competency, treating disorders associated with the immune system, inhibiting inflammatory response, treating disorders associated with inflammatory response, enhancing anti-tumor response, and treating disorders associated with response to tumor formation and growth in mammals by administering an isolated bioactive component identified as a quinic acid analog (quinic acid lactone), whether as free acid or as a quinic acid salt, including quinic acid ammonium salt. ...
https://www.optigenex.com/ac11-patents
SHJG 6735 - ABC transporter substrate-binding protein - Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) - SHJG...SHJG 6735 - ABC transporter substrate-binding protein - Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) - SHJG...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
https://www.uniprot.org/uniprot/H2JXL4
Synthesis of the RTH-type layer: the first small-pore, two dimensional layered zeolite precursor - Semantic ScholarSynthesis of the RTH-type layer: the first small-pore, two dimensional layered zeolite precursor - Semantic Scholar
There are several distinct two-dimensional zeolite building layers that can condense through different stacking arrangements of the layers to form various three-dimensional framework materials. All known building layers are dense layers in that they do not contain 8-membered ring (MR) or larger pores perpendicular to the two-dimensional layers. Herein, we report a new material (CIT-10) that consists of a two-dimensional layer (termed
https://www.semanticscholar.org/paper/Synthesis-of-the-RTH-type-layer-the-first-small-po-Schmidt-Xie/6b140e6387b5d606b632c15093863464b0f5109f
AminocyclitolAminocyclitol
"Biosynthesis of the C7-cyclitol Moiety of Acarbose inActinoplanes Species SE50/110 7-O-PHOSPHORYLATION OF THE INITIAL CYCLITOL ... In validamycin biosynthesis, the C-N linkage which connect the C7 cyclitol moiety to the other was found to be formed by ... The aminocyclitols are compounds related to cyclitols. They possess features of relative and absolute configuration that are ... "Biosynthesis of the cyclitol moiety of pyralomicin 1a in Nonomuraea spiralis MI178-34F18". The Journal of Antibiotics. 55 (6): ...
https://en.wikipedia.org/wiki/Aminocyclitol
Inositol 1-methyltransferaseInositol 1-methyltransferase
Wagner I, Hofmann H, Hoffmann-Ostenhof O (1969). "[Biosynthesis of cyclitols. 23. A soluble enzyme from pea seedlings ...
https://en.wikipedia.org/wiki/Inositol_1-methyltransferase
Inositol 3-methyltransferaseInositol 3-methyltransferase
Hofmann H, Wagner I, Hoffmann-Ostenhof O (1969). "[Biosynthesis of cyclitols. XXIV. A soluble enzyme from Vinca rosea ...
https://en.wikipedia.org/wiki/Inositol_3-methyltransferase
ConduritolConduritol
They are therefore cyclic polyols or cyclitols. The compounds in this group exhibit cis-trans isomerism, with six isomers that ...
https://en.wikipedia.org/wiki/Conduritol
CiceritolCiceritol
... is a cyclitol. It is a pinitol digalactoside that can be isolated from seeds of chickpea, lentil and white lupin. ...
https://en.wikipedia.org/wiki/Ciceritol
PinpollitolPinpollitol
... is a cyclitol. It is a di-O-methyl-(+)-chiro-inositol that can be isolated from Pinus radiata. Gallagher, R (1975 ...
https://en.wikipedia.org/wiki/Pinpollitol
ViscumitolViscumitol
... is a cyclitol. It is a dimethyl-ether of muco-inositol that can be isolated from Viscum album. Richter, Andreas ( ...
https://en.wikipedia.org/wiki/Viscumitol
OnonitolOnonitol
... is a cyclitol. It is a 4-O-methyl-myo-inositol and is a constituent of Medicago sativa. E. A. McComb and V. V. Rendig ...
https://en.wikipedia.org/wiki/Ononitol
BornesitolBornesitol
... is a cyclitol. It can be found in the gentianaceae and menyanthaceae plant families. Chemically, it is a methyl ...
https://en.wikipedia.org/wiki/Bornesitol
5-Deoxyinositol5-Deoxyinositol
... (quercitol) is a cyclitol. It can be found in wines aged in oak wood barrels. It can also be found in Quercus ... "Analysis of cyclitols in different Quercus species by gas chromatography-mass spectrometry". Journal of the Science of Food and ...
https://en.wikipedia.org/wiki/5-Deoxyinositol
PinitolPinitol
... is a cyclitol, a cyclic polyol. It is a known anti-diabetic agent isolated from Sutherlandia frutescens leaves. Gall ... A cyclitol derivative can be found in the marine sponge Petrosia sp. Narayanan, 1987 Introduction Sutherlandia frutescens - ... Pages 1745-1751 A cyclitol derivative as a replication inhibitor from the marine sponge Petrosia sp. Kim D.-K.; Young Ja Lim; ...
https://en.wikipedia.org/wiki/Pinitol
QuebrachitolQuebrachitol
... is a naturally occurring optically active cyclitol, a cyclic polyol. It can be found in Allophylus edulis and in ...
https://en.wikipedia.org/wiki/Quebrachitol
Allophylus edulisAllophylus edulis
Quebrachitol is a cyclitol, a cyclic polyol found in A. edulis. This plant has several different common names in Portuguese: ...
https://en.wikipedia.org/wiki/Allophylus_edulis
Ralph L. ObendorfRalph L. Obendorf
He has studied cell wall polysaccharides and the role of sugars, cyclitols and methanol in seed deterioration and germplasm ... Dependence on flatulence-producing oligosaccharides and cyclitols-review and survey". Seed Science Research. 4: 385-405. doi: ... research on the biology of seeds included characterizing the molecular structure and synthesis of galactosyl cyclitols; ...
https://en.wikipedia.org/wiki/Ralph_L._Obendorf
ValienolValienol
... (streptol) is a C-7 cyclitol similar in structure to valienamine. Petr Sedmera; Petr Halada & Stanislav Pospisil (2009 ...
https://en.wikipedia.org/wiki/Valienol
Marsdenia cundurangoMarsdenia cundurango
... is known to contain conduritol, a cyclitol or cyclic polyol. It was first isolated in 1908 by K. Kübler ...
https://en.wikipedia.org/wiki/Marsdenia_cundurango
Streptomyces lincolnensisStreptomyces lincolnensis
It also produces valienol, a C-7 cyclitol similar in structure to valienamine. The name of the species is derived from Lincoln ...
https://en.wikipedia.org/wiki/Streptomyces_lincolnensis
ValienamineValienamine
June 2002). "Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the ... initial cyclitol precursor leads to proposal of a new biosynthetic pathway". J. Biol. Chem. 277 (25): 22853-62. doi:10.1074/jbc ...
https://en.wikipedia.org/wiki/Valienamine
Aspidosperma quebracho-blancoAspidosperma quebracho-blanco
Quebrachitol is a cyclitol, a cyclic polyol found in the bark of A. quebracho. 'Pendula' - with weeping branches. Trees portal ...
https://en.wikipedia.org/wiki/Aspidosperma_quebracho-blanco
Rubber tappingRubber tapping
... a cyclitol or cyclic polyol. In information technology the term 'Rubber tapping' is sometimes used as a lampoon for planned ...
https://en.wikipedia.org/wiki/Rubber_tapping
Martin BanwellMartin Banwell
March 2005). "Use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding ...
https://en.wikipedia.org/wiki/Martin_Banwell
A valueA value
Huang, C.-Y.; Cabell, L.A.; Anslyn, E.V. (1994). "Molecular Recognition of Cyclitols by Neutral Polyaza-Hydrogen-Bonding ...
https://en.wikipedia.org/wiki/A_value
Shikimic acidShikimic acid
... , more commonly known as its anionic form shikimate, is a cyclohexene, a cyclitol and a cyclohexanecarboxylic acid ...
https://en.wikipedia.org/wiki/Shikimic_acid
Hydrolysable tanninHydrolysable tannin
At the center of a hydrolyzable tannin molecule, there is a carbohydrate (usually D-glucose but also cyclitols like quinic or ...
https://en.wikipedia.org/wiki/Hydrolysable_tannin
FuguFugu
... aspects for constructing complex multi-functionalized cyclitols with branched-chain structures". Nat. Prod. Commun. 10 (5; May ...
https://en.wikipedia.org/wiki/Fugu
Cocculus carolinusCocculus carolinus
... two cyclitols, (+)quercitol and (−)viburnitol; a lactone, loliolide; and three alkaloids, sinoacutine, magnoflorine, and ...
https://en.wikipedia.org/wiki/Cocculus_carolinus
PolyolPolyol
Cyclitol Polyurethane Hubert Schiweck, Albert Bär, Roland Vogel, Eugen Schwarz, Markwart Kunz, Cécile Dusautois, Alexandre ...
https://en.wikipedia.org/wiki/Polyol
C7H14O6C7H14O6
... a cyclitol Pinitol, a cyclitol Quebrachitol, a cyclitol. ... a cyclitol Methyl-α-D-galactose Methylglucoside, a glucose ...
https://en.wikipedia.org/wiki/C7H14O6
C6H10O4C6H10O4
... a cyclitol or cyclic polyol Dianhydrohexitols Isoidide Isomannide Isosorbide Ethylidene diacetate Glucal. ...
https://en.wikipedia.org/wiki/C6H10O4
Muco-InositolMuco-Inositol
... www.chem.qmul.ac.uk/iupac/cyclitol/myo.html Eggers, S. Acree, T. & Shallenberger, R. (2000) Sweetness chemoreception theory and ...
https://en.wikipedia.org/wiki/Muco-Inositol
Cyclitol - WikipediaCyclitol - Wikipedia
Cyclitols are one of the compatible solutes which are formed in a plant as a response to salt or water stress. Some cyclitol (e ... Nomenclature of Cyclitols on chem.qmul.ac.uk List of cyclitol molecules on chemicalland21.com. ... Cyclitols are cycloalkanes containing a hydroxyl group on each of three or more ring atoms. They are cyclic polyols. ...
https://en.wikipedia.org/wiki/Cyclitol
Computational Characterisation of Mesogenes Containing Carbohydrate- and Cyclitol-Based Building Blocks - Kölner...Computational Characterisation of Mesogenes Containing Carbohydrate- and Cyclitol-Based Building Blocks - Kölner...
Computational Characterisation of Mesogenes Containing Carbohydrate- and Cyclitol-Based Building Blocks. PhD thesis, ...
https://kups.ub.uni-koeln.de/5184/
PDF] Effect of Lupin Cyclitols on Pea Aphid Probing Behaviour - Semantic ScholarPDF] Effect of Lupin Cyclitols on Pea Aphid Probing Behaviour - Semantic Scholar
In aphid bodies, both cyclitols were traced, respectively, to the host plant treat- ment. The new cyclitols in pea tissues did ... This may reflect difficulties in the uptake of the phloem sap, and point to lupin cyclitols as being responsible, at least in ... However, the aphid behaviour on cyclitol-treated plants as compared to their behaviour on the control was slightly altered. Non ... Feeding of peas with cyclitols at a concentration of 10 mM, caused a selective accumulation of d-pinitol and d-chiro-inositol ...
https://www.semanticscholar.org/paper/Effect-of-Lupin-Cyclitols-on-Pea-Aphid-Probing-Kordan-Lahuta/59ec7783085d7a0b44e223ce0bce113b0fe88fab
Aminocyclitol - WikipediaAminocyclitol - Wikipedia
"Biosynthesis of the C7-cyclitol Moiety of Acarbose inActinoplanes Species SE50/110 7-O-PHOSPHORYLATION OF THE INITIAL CYCLITOL ... In validamycin biosynthesis, the C-N linkage which connect the C7 cyclitol moiety to the other was found to be formed by ... The aminocyclitols are compounds related to cyclitols. They possess features of relative and absolute configuration that are ... "Biosynthesis of the cyclitol moiety of pyralomicin 1a in Nonomuraea spiralis MI178-34F18". The Journal of Antibiotics. 55 (6): ...
https://en.wikipedia.org/wiki/Aminocyclitol
Wiley: Asymmetric Synthesis of Natural Products, 2nd Edition - Ari M. P. KoskinenWiley: Asymmetric Synthesis of Natural Products, 2nd Edition - Ari M. P. Koskinen
4.6 Cyclitols 138. References 142. 5 Amino Acids, Peptides, and Proteins 145 ...
http://www.wiley.com/WileyCDA/WileyTitle/productCd-1119976693.html
Inositol: Uses, Side Effects, Interactions, Dosage, and WarningInositol: Uses, Side Effects, Interactions, Dosage, and Warning
Nomenclature of Cyclitols. IUPAC Commission on the Nomenclature of Organic Chemistry (CNOC) and IUPAC-IUB Commission on ... Biochemical Nomenclature (CBN). Available at: http://www.chem.qmw.ac.uk/iupac/cyclitol/ (Accessed 23 January 2004). ...
https://www.webmd.com/vitamins/ai/ingredientmono-299/inositol
AlismatalesAlismatales
Plant sympodial - Thalassodendron), stems erect; (roots branched), (root hairs 0); distinctive cyclitols; rhizome with two or a ... Additional information is taken from Kuo and McComb (1989, 1998: general); for cyclitols, see Drew (1983) and for floral ...
http://www.mobot.org/mobot/research/apweb/orders/Alismatalesweb.htm
Leiv K. Sydnes | University of BergenLeiv K. Sydnes | University of Bergen
Sydnes, Leiv K.; Hudlicky, T.; Cebulak, M. 1994. Cyclitols and Their Derivatives. (Bokomtale). Kjemi. 53: 28. ...
https://www.uib.no/en/persons/Leiv.Sydnes
carbohydrate (CHEBI:16646)carbohydrate (CHEBI:16646)
Cyclitols are generally not regarded as carbohydrates.. Stars This entity has been manually annotated by the ChEBI Team. ...
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16646
UDP-6-sulfoquinovose (CHEBI:15855)UDP-6-sulfoquinovose (CHEBI:15855)
Cyclitols are generally not regarded as carbohydrates.. nucleotide Definition : A nucleotide is a nucleoside phosphate ...
https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:15855
Physiology of Stressed Crops, Vol. 4: Osmoregulation and ProtectionPhysiology of Stressed Crops, Vol. 4: Osmoregulation and Protection
Cyclitols: Introduction; Cold stress; Salinity stress; Drought stress; Nutrient stress; The stress of ROS; Improvement work; ...
https://www.routledge.com/Physiology-of-Stressed-Crops-Vol-4-Osmoregulation-and-Protection/Gupta/p/book/9781578084401?utm_source=crcpress.com&utm_medium=referral
The Biosynthesis of Polysaccharides | SpringerLinkThe Biosynthesis of Polysaccharides | SpringerLink
For many years studies of the structure and biosynthesis of saccharides formed a specialised and somewhat abstruse part of biochemistry, with little or no place in molecular biology. In recent years t
https://link.springer.com/book/10.1007%2F978-1-4615-9873-2
Mutasynthesis and Directed Biosynthesis for the Production of New Antibiotics | SpringerLinkMutasynthesis and Directed Biosynthesis for the Production of New Antibiotics | SpringerLink
II Conversion of non-amino containing cyclitols to aminoglycoside antibiotics. J. Antibiot. 30: 90-105.CrossRefGoogle Scholar ... In Amino-cyclitol antibiotics (Rinehart, K. L., Jr. and T. Suami Eds.), ACS Symposium Series No. 125. American Chemical Society ...
https://link.springer.com/chapter/10.1007/978-1-4684-4460-5_16
Frontiers | Proteomics, metabolomics, and ionomics perspectives of salinity tolerance in halophytes | Plant ScienceFrontiers | Proteomics, metabolomics, and ionomics perspectives of salinity tolerance in halophytes | Plant Science
Orthen, B., Popp, M., and Smirnoff, N. (1994). Hydroxyl radical scavenging properties of cyclitols. Proc. R. Soc. Edinb. Sec. B ... Loewus, F. A., and Dickinson, D. B. (1982). "Cyclitols," in Encyclopedia of Plant Physiology: Plant Carbohydrates 1. ...
https://www.frontiersin.org/articles/10.3389/fpls.2015.00537/full
Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses | Journal of...Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses | Journal of...
For example, it has been found that cyclitols (cyclic polyols; Fig. 2) and polyols such as mannitol, which are used by many ... Orthen, B., Popp, M. and Smirnoff, N. (1994). Hydroxyl radical scavenging properties of cyclitols. Proc. R. Soc. Edinburgh Sect ...
http://jeb.biologists.org/content/208/15/2819
Patent US5036007 - Method for reproducing coniferous plants by somatic embryogenesis using ... - Google PatentsPatent US5036007 - Method for reproducing coniferous plants by somatic embryogenesis using ... - Google Patents
The cyclitols are normally six carbon ring compounds that are hexahydroxylated. The most readily available cyclitol is myo- ...
http://www.google.com/patents/US5036007?dq=5527183
Academy of Europe: Areas of ActivityAcademy of Europe: Areas of Activity
Carbohydrates and cyclitols Go to *Carbon dioxide Capture and Storage Go to ...
https://acadeuro.org/ae/Acad_Main/Sections/Chemical_sciences/Areas_of_Activity
The Scout Report for Science & Engineering - March 3, 1999 | Internet ScoutThe Scout Report for Science & Engineering - March 3, 1999 | Internet Scout
Nomenclature of Cyclitols. http://www.chem.qmw.ac.uk/iupac/cyclitol/. Nomenclature of Tocopherols and Related Compounds. http ...
https://scout.wisc.edu/report/se/1999/0303
International Union of Pure and Applied ChemistryInternational Union of Pure and Applied Chemistry
P-104 Cyclitols. P-105 Nucleosides. P-106 Nucleotides. P-107 Lipids ...
https://old.iupac.org/reports/provisional/abstract04/favre_310305.html
Frontiers | Agricultural practices altered soybean seed protein, oil, fatty acids, sugars, and minerals in the Midsouth USA |...Frontiers | Agricultural practices altered soybean seed protein, oil, fatty acids, sugars, and minerals in the Midsouth USA |...
Obendorf, R. L. (1997). Oligosaccharides and galactosyl cyclitols in seed desiccation tolerance. Seed Sci. Res. 7, 63-74. doi: ...
https://www.frontiersin.org/articles/10.3389/fpls.2015.00031/full
Hopanoids as functional analogues of cholesterol in bacterial membranes | PNASHopanoids as functional analogues of cholesterol in bacterial membranes | PNAS
New bacteriohopanetetrol cyclitol ethers from the methylotrophic bacterium Methylobacterium-organophilum. Eur J Biochem 151(2): ... predominately composed of a bacteriohopanetetrol cyclitol ether (BHT-CE) and its guanidine-modified derivative (BHT-GCE) (28) ( ...
https://www.pnas.org/content/112/38/11971.long
FabalesFabales
in seeds, 5-deoxyflavonoids, C-glycosylflavonoids, pinitol [cyclitol] +; cork also in outer cortex; (wood storied); secretory ...
http://www.mobot.org/MOBOT/research/APweb/orders/Fabalesweb.htm
CiNii Articles - MATSUI KatsuhikoCiNii Articles - MATSUI Katsuhiko
Microbial degradation of validamycin A by Flavobacterium saccharophilum. Enzymatic cleavage of C-N linkage in validoxylamine A.:ENZYMATIC CLEAVAGE OF C-N LINKAGE IN VALIDOXYLAMINE A （1984 ...
https://ci.nii.ac.jp/author?q=MATSUI+Katsuhiko
Preamble, 2-Carb-0 & 2-Carb-1Preamble, 2-Carb-0 & 2-Carb-1
Nomenclature of cyclitols, 1973 [8]. Numbering of atoms in myo-inositol, 1988 [9]. Symbols for specifying the conformation of ... Cyclitols are generally not regarded as carbohydrates. Their nomenclature is dealt with in other recommendations [8,9].. 2-Carb ... 8. IUPAC-IUB Commission on Biochemical Nomenclature (CBN), Nomenclature of cyclitols (Recommendations 1973), Biochem. J., 153, ...
https://www.qmul.ac.uk/sbcs/iupac/2carb/00n01.html
Human Metabolome Database: Showing metabocard for PIP(18:1(11Z)/20:4(8Z,11Z,14Z,17Z)) (HMDB0009968)Human Metabolome Database: Showing metabocard for PIP(18:1(11Z)/20:4(8Z,11Z,14Z,17Z)) (HMDB0009968)
Cyclitol or derivatives. *Dicarboxylic acid or derivatives. *Organic phosphoric acid derivative. *Phosphoric acid ester ...
https://hmdb.ca/metabolites/HMDB0009968
Suppressive effects of swainsonine on C6 glioma cell in vitro and in vivo. - Free Online LibrarySuppressive effects of swainsonine on C6 glioma cell in vitro and in vivo. - Free Online Library
NF-[kappa]B inhibitory activity of cyclitols isolated from hancovnia speciosa.. Next Article:. Complex Herbs - Complete ...
https://www.thefreelibrary.com/Suppressive+effects+of+swainsonine+on+C6+glioma+cell+in+vitro+and+in+...-a0221083856
A Role for Sorbitol in Desiccation Tolerance of Developing Maize Kernels: Inference from the Properties of Maize Sorbitol...A Role for Sorbitol in Desiccation Tolerance of Developing Maize Kernels: Inference from the Properties of Maize Sorbitol...
Loewus FA (1990) Cyclitols. In PM Dey, JB Harborne, eds. Methods in Plant Biochemistry, Vol. 2, Academic Press, Inc., New York ...
https://rd.springer.com/chapter/10.1007/978-3-642-79133-8_22
Mills SJ[au] - PubMed - NCBIMills SJ[au] - PubMed - NCBI
A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Mills+SJ%5Bau%5D&dispmax=50
Neuroscience Information Framework (NIF) Standard Ontology - carbohydrate - Classes | NCBO BioPortalNeuroscience Information Framework (NIF) Standard Ontology - carbohydrate - Classes | NCBO BioPortal
Cyclitols are generally not regarded as carbohydrates.. subClassOf. http://purl.obolibrary.org/obo/CHEBI_78616 ...
http://bioportal.bioontology.org/ontologies/NIFSTD?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_16646
EC 1.1.1.1 to EC 1.1.1.50EC 1.1.1.1 to EC 1.1.1.50
The numbering system used for the 3-dehydroquinate is that of the recommendations on cyclitols, sections I-8 and I-9: and is ...
https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC1/0101a.html
MoietyDibasic cyclitolGalactosyl cyclitolsCyclicAminoglycoside antibioticsDerivativesOligosaccharidesAlditolsAnalogueHydroxylBiosyntheticAcarboseAminoglycosidesShikimicCompoundsSecondaryWaterPresent
Moiety5
  • In validamycin biosynthesis, the C-N linkage which connect the C7 cyclitol moiety to the other was found to be formed by unprecedented actions of nucleotidyltransferase and glycosyltransferase-like enzymes (which is termed pseudoglycosyltransferase). (wikipedia.org)
  • Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. (genome.jp)
  • According to the news reporters, the research concluded: "Targeted disruption of the gene encoding the N-glycosyltransferase, prlH, abolished pyralomicin production, and recombinant expression of PrlA confirms the activity of this enzyme as a sugar phosphate cyclase involved in the formation of the C7-cyclitol moiety. (equities.com)
  • The indole moiety of Trp140 is stacked on the cyclitol and 4-amino-6-deoxyglucose residues located at subsites -6 and -5 within a 4 A distance. (rcsb.org)
  • Pseudotetrasaccharide containing an unsaturated cyclitol moiety. (drugfuture.com)
Dibasic cyclitol2
  • Its chemical structure, based on several aminated sugars joined to a dibasic cyclitol ( Fig. 1 ), can hold up to six positive charges at acidic pH. (rupress.org)
  • The basic chemical structure required for both potency and the spectrum of antimicrobial activity of aminoglycosides is that of one or several aminated sugars joined in glycosidic linkages to a dibasic cyclitol. (asm.org)
Galactosyl cyclitols2
  • Consequently, plant biologists have been searching for other desiccation-protecting factors such as galactosyl cyclitols that might substitute for RFOs in promoting desiccation tolerance but without having the unwanted anti-nutritional side effects of RFOs ( Horbowicz and Obendorf, 1994 ). (plantphysiol.org)
  • Peterbauer, T. and Richter, A. (2001) Biochemistry and Physiology of Raffinose Family Oligosaccharides and Galactosyl Cyclitols in Seeds. (scirp.org)
Cyclic1
  • Polyols (or sugar alcohols), the reduced form of aldoses and ketoses, can be either cyclic (cyclitols) or linear (alditols) and are present in all living forms, from bacteria to animals. (plantcell.org)
Aminoglycoside antibiotics1
  • II Conversion of non-amino containing cyclitols to aminoglycoside antibiotics. (springer.com)
Derivatives3
  • Cyclitols such as myo-inositol and more importantly its methylated derivatives pinitol and ononitol are now known to play some role in salinity and drought. (science20.com)
  • In spite of its abundance in nature and ready availability, myo-inositol has not been utilized widely as the starting material for the synthesis of natural products other than cyclitol derivatives. (elsevier.com)
  • Given that regioselective ring cleavage of the cyclohexane ring in optically active and functionalized cyclitol derivatives is possible, myo-inositol is expected to be a potential precursor with stereochemical diversity for novel chiral building blocks in the synthesis of various natural products. (elsevier.com)
Oligosaccharides1
  • Horbowicz, M. and Obendorf, R.L. (1994) Seed Desiccation Tolerance and Storability: Dependence on Flatulence-Producing Oligosaccharides and Cyclitols-Review and Survey. (scirp.org)
Alditols1
  • Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. (waterstones.com)
Analogue1
  • Analogues where these parts of the molecule have been excised, have led to the introduction of ThrCer and its cyclitol analogue ThrCer-6. (bham.ac.uk)
Hydroxyl2
  • Cyclitols are cycloalkanes containing a hydroxyl group on each of three or more ring atoms. (wikipedia.org)
  • Pseudo-maltononaose occupies subsites -6 to +3 and induces the conformational change of Glu266 and Asp333 to form a salt linkage with the N-glycosidic amino group and a hydrogen bond with secondary hydroxyl groups of the cyclitol residue bound to subsite -1, respectively. (rcsb.org)
Biosynthetic2
  • 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway. (genome.jp)
  • A gene cassette encoding C7-cyclitol biosynthetic enzymes was identified upstream of the benzopyranopyrrole-specific ORFs. (equities.com)
Acarbose1
  • Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. (agscientific.com)
Aminoglycosides1
  • Most aminoglycosides contain a 2-deoxystreptamine cyclitol. (asmscience.org)
Shikimic3
  • Some cyclitol (e.g. quinic or shikimic acid) are parts of hydrolysable tannins. (wikipedia.org)
  • Shikimic acid, is a cyclohexene, a cyclitol and a cyclohexanecarboxylic acid. (sbwire.com)
  • Shikimic acid , more commonly known as its anionic form shikimate , is a cyclohexene , a cyclitol and a cyclohexanecarboxylic acid . (wikipedia.org)
Compounds1
  • The aminocyclitols are compounds related to cyclitols. (wikipedia.org)
Secondary1
  • myo-Inositol, a cyclitol (cyclohexanepolyol) which is classified as a type of carbohydrates, occurs widely in nature and is known as a constituent of a secondary messenger in cells which stimulates the release of calcium from storage site. (elsevier.com)
Water2
  • Cyclitols are one of the compatible solutes which are formed in a plant as a response to salt or water stress. (wikipedia.org)
  • Cyclitols and carbohydrates in leaves and roots of 13 Eucalyptus species suggest contrasting physiological responses to water deficit. (semanticscholar.org)
Present1
  • The cyclitols: d-pinitol, d-chiro-inositol are naturally present in the tissues of Lupinus angustifolius. (semanticscholar.org)