Curcumin

Curcuma

Anti-Inflammatory Agents, Non-Steroidal

Antineoplastic Agents

Piperidones

Cell Line, Tumor

Curcumin

Curcumin synthase

Turmeric

Ganugupahad

Lipofuscin

Traditional Chinese medicine

Govindarajan Padmanaban

Derek Lowe (chemist)

Curcuminoid

Desmethoxycurcumin

Medicinal plants

EF-24

History of herbalism

Miriam Rossi (chemist)

Dibenzoylmethane

Rubrocurcumin

List of 5α-reductase inhibitors

Turmerone

Traumatic brain injury

Alternative cancer treatments

Monoamine oxidase inhibitor

Drug discovery

Reagent

List of phytochemicals in food

Nutritional immunology

GSK-3

Zingiberaceae

Bisdemethoxycurcumin

Avadhesha Surolia

Ulcerative colitis

Active ingredient in turmeric3

• The active ingredient in turmeric is curcumin . (solgar.com)
• Numerous studies have shown that curcumin, the active ingredient in turmeric, has positive effects on many parts of the body, including the digestive system, joints, brain, and organs. (adustyframe.com)
• Curcumin is the primary active ingredient in turmeric. (ironmagazine.com)

Shown that curcumin4

• Animal studies going back nearly five years have shown that curcumin supplementation reduces depressive-like behaviors in established models of depression. (lifeextension.com)
• In addition to these clinical benefits, research has shown that curcumin influences several salivary, urinary, and blood biomarkers of oxidative stress and inflammation. (lifeextension.com)
• Our previous studies have shown that curcumin could enhance radiosensitization in NPC by variant pathways through the regulation of different coding- or noncoding-RNAs [ 9 ]. (jcancer.org)
• Current studies have shown that curcumin exerts prominent inhibitory effects on various cancer stem cells through different pathways. (jcancer.org)

Curcuma8

• High Quality Curcumin extract Powder Product Name: Curcumin extract Other Name: Turmeric yellow, Diferuloylmethane Botanical Origin : Curcuma longa L. Appearance: Yellow to orange powder. (21food.com)
• 1: Specialized manfacturer 2: R&D team and cooperates closely 3: Free Sample available for your test Product detail showing English name: Curcumin Extract Latin name: Curcuma longa Linn Orginal p. (21food.com)
• 1.Curcuma Extract 2.Curcumin 90%,95% 3.GMP&BV Certificates 4.Free sample about 10g 5.MOQ:1KG GMP Certified Manufacturer High Quality Curcumin Extract Details: 1.Product Name Curcuma Extract 2.Lat. (21food.com)
• curcuma longa extract supplier from India Curcumin Extract 95% Features:- 1.High Quality Product 2.Made from Natural Source. (21food.com)
• curcuma longa extract supplier from India TURMERIC, CURCUMIN EXTRACT BENEFITS Turmeric herb (Curcuma longa) is a plant nat. (21food.com)
• Full Spectrum Curcumin (Polysorbate 80 (emulsifier), Turmeric Extract (Curcuma longa) [rhizome]), Vegetable Cellulose. (solgar.com)
• Enhansa is a proprietary blend of curcuminoids derived from the rhizomes of Curcuma longa (Curcumin). (ageofautism.com)
• Curcumin (CUR), a natural bioactive compound extracted from a traditional Chinese medicinal herb turmeric ( Curcuma longa ), has been reported to exhibit potent antitumor activities against different types of cancer, including NPC in both in vivo and in vitro models [ 8 ]. (jcancer.org)

Supplementation3

• The figure below shows that exercise increased carotid arterial compliance, and that curcumin supplementation boosted this effect significantly. (ironmagazine.com)
• Interestingly, curcumin supplementation of CCL 4 treated group decreased expression of inflammatory markers as well as improved antioxidant status and histoarchitecture in liver and spleen. (scialert.net)
• A placebo-controlled, randomized double-blind clinical trial published in Phytotherapy Research titled Effects of Supplementation with Curcuminoids on Dyslipidemia in Obese Patients: A Randomized Crossover Trial (Mohammadi et al, 2012) reported that Sabinsa's Curcumin C 3 Complex ® led to a significant reduction in serum triglycerides concentration in a randomized crossover clinical trial. (sabinsa.com)

Effects of curcumin2

• We will test the hypothesis that the products of oxidative transformation are mediators of pharmacological effects of curcumin. (nih.gov)
• We investigated the effects of curcumin ingestion and aerobic exercise training on flow-mediated dilation as an indicator endothelial function in postmenopausal women. (ironmagazine.com)

Suggest that curcumin2

• Small clinical studies suggest that curcumin from turmeric is helpful for indigestion, ulcerative colitis, certain liver conditions such as non-alcoholic fatty liver disease (NAFLD), rheumatoid arthritis and osteoarthritis, seasonal allergies, as well as depression, and may have benefit in some precancerous conditions. (consumerlab.com)
• These observations suggest that curcumin may improve muscle recovery and differentiation/regeneration processes. (ergo-log.com)

Turmeric and curcumin4

• Find the Best Turmeric and Curcumin Supplements & Spices. (consumerlab.com)
• What are turmeric and curcumin? (consumerlab.com)
• Turmeric and curcumin are not well absorbed on their own and it's generally best to take turmeric/curcumin with food containing some fat in order to increase absorption. (consumerlab.com)
• Despite being a crucial element in boosting overall health, turmeric and curcumin may not easily absorb into the body better than other plant-based extracts. (adustyframe.com)

Properties of curcumin2

• To study pharmacokinetic properties of curcumin, a fast sensitive assay method was developed to determine curcumin and its metabolite tetrahydrocurcumin in rat plasma. (greenmedinfo.com)
• Cavaleri's research has proven for the first time how the modified curcumin extract targets and neutralizes a key protein central in the regulation of inflammation, while significantly enhancing the efficacy of the anti-inflammatory properties of curcumin. (totalhealthmagazine.com)

Bioavailability of curcumin2

• Complex formation resulted in an obvious increase in bioavailability of curcumin in rat in vivo according to the assay by above LC/MS/MS method. (greenmedinfo.com)
• In counterbalance, the high metabolic instability and poor systemic bioavailability of curcumin limit its therapeutic efficacy in human. (nih.gov)

Dietary5

• Curcumin is one of several curcuminoid compounds found in turmeric that give turmeric its color and antioxidant and anti-inflammatory properties, making turmeric root powders and extracts useful as dietary supplements (see What It Is ). (consumerlab.com)
• Turmeric Curcumin Plus is an organic dietary supplement designed to support the health of joints and muscles, improve the conditions of the immune system, and relieve varying degrees of discomfort and pain with antioxidant and anti-inflammatory properties. (adustyframe.com)
• The purpose of this study was to examine the antioxidant, anti-inflammatory and anti-amyloidogenic properties of dietary curcumin, and its metabolite tetrahydrocurcumin (TC). (nih.gov)
• and 3) to understand how these stem cell regulating pathways may be regulated by dietary components, including curcumin and sulforaphane. (nih.gov)
• We demonstrate here that curcumin (diferuloylmethane), a dietary polyphenol, at nanomolar concentrations specifically restores cigarette smoke extract (CSE)- or oxidative stress-impaired HDAC2 activity and corticosteroid efficacy in vitro with an EC(50) of approximately 30 nM and 200 nM, respectively. (nih.gov)

Curcuminoids5

• The typical daily dose ranges from 500 mg to 2,000 mg of curcuminoids (most of which is curcumin) from turmeric extracts (see Dosage ), which can often be as much as 95% curcuminoids. (consumerlab.com)
• Turmeric spice powder is much less concentrated - only about 3% curcuminoids- yet some turmeric supplements are just turmeric spice placed in capsules, offering much lower amounts of curcumin than supplements made from turmeric extracts. (consumerlab.com)
• Among supplements that passed testing, we identified our Top Pick -- which provided curcumin at one of the lowest costs and includes a bioavailability enhancer to boost the amount of curcuminoids making it into your bloodstream. (consumerlab.com)
• Curcumin 95 is a concentrate of 95% curcuminoids, which are powerful antioxidants found in the spice turmeric root. (needs.com)
• It is the specific ratio of curcuminoids, along with the specialized method of extraction, which allows for the unique benefits of Enhansa as compared to other Curcumin products. (ageofautism.com)

Diferuloylmethane1

• Curcumin or diferuloylmethane is an active principle present in the turmeric, which gives a characteristic flavor and yellow color to different cuisines. (hilarispublisher.com)

Regular curcumin3

• Superior absorption versus regular curcumin! (solgar.com)
• According to the manufacturer the body absorbs this form of curcumin better than regular curcumin. (ironmagazine.com)
• Regular curcumin ingestion and aerobic exercise may be effective lifestyle modifications for minimizing and reversing the loss of carotid arterial compliance with advancing age in women. (ironmagazine.com)

Bioperine3

• If you can't always take turmeric or curcumin with food, see Absorption and Bioavailability to learn about bioavailability enhancement with ingredients such as BCM-95, C3 (which includes the black pepper extract, piperine, branded as Bioperine), CurcuWin, Longvida, Meriva, NovaSol, and Theracurmin. (consumerlab.com)
• Its formulation contains an impressive blend of these high-quality ingredients: turmeric extract, its active ingredient curcumin, and the highly acclaimed BioPerine(r) compound. (adustyframe.com)
• At the same 1,000 mg /day dose, curcumin enhanced with bioperine reduced the symptoms of anxiety among a group of obese subjects with depression and anxiety. (lifeextension.com)

Oxidative stress5

• Curcumin is well known for its anti-inflammatory and oxidative stress-fighting properties. (lifeextension.com)
• Curcumin, long recognized for its ability to fight both oxidative stress and inflammation, has recently emerged as a leading brain health-promoting supplement. (lifeextension.com)
• This data suggested that curcumin protect the liver and spleen from acute CCL 4 induced injury in a rodent model by suppressing hepatic and splenic oxidative stress expression levels of inflammatory markers. (scialert.net)
• Purpose: To explore the role and mechanism of curcumin (Cur) in reducing oxidative stress damage in rats with nephrolithiasis induced by ethylene glycol (EG). (bvsalud.org)
• Conclusion: Curcumin could reduce the oxidative stress damage caused by EG-induced kidney stones. (bvsalud.org)

1,000 mg1

• For example, taking 1,000 mg a day of a bioavailable curcumin has been found to be more effective than placebo at improving mood-related symptoms on standard depression scales. (lifeextension.com)

Pathways1

• The oncogenic pathways inhibited by curcumin encompass the members of epidermal growth factor receptors (EGFR and erbB2), sonic hedgehog (SHH)/GLIs and Wnt/β-catenin and downstream signaling elements such as Akt, nuclear factor-kappa B (NF-κB) and signal transducers and activators of transcription (STATs). (nih.gov)

Vitro2

• Although a large number of in vitro targets of curcumin have been identified, the precise chemical-molecular mechanism(s) of its biological activities have not been elucidated. (nih.gov)
• ELP-curcumin conjugates were shown to display high drug loading, rapidly release curcumin in vitro via degradable carbamate bonds, and retain in vitro bioactivity against TNFα-induced cytotoxicity and monocyte activation with IC50 only two-fold higher than curcumin. (duke.edu)

Therapeutic7

• The concept of oxidative activation could result in a new paradigm of understanding the structure and function of curcumin with important implications for its clinical application as a therapeutic CAM agent. (nih.gov)
• This discovery is significant because it means curcumin pharmacology can now be more precisely targeted for therapeutic results. (totalhealthmagazine.com)
• Overall, these results show a neat little epigenetic mechanism where curcumin exerts a therapeutic role (in a dose dependent manner) in the treatment of neuropathic pain by down-regulating a HAT, which leads to the repression of key activity dependent pain inducing target genes. (epigenie.com)
• Therefore, curcumin are potential therapeutic antioxidant agents against acute hepatotoxicity and spleenotoxicity. (scialert.net)
• Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to its chemopreventive, antitumoral, radiosensibilizing and chemosensibilizing activities against various types of aggressive and recurrent cancers. (nih.gov)
• Of great therapeutic interest, the selective delivery of synthetic analogs or nanotechnology-based formulations of curcumin to tumors, alone or in combination with other anticancer drugs, may improve their chemopreventive and chemotherapeutic efficacies against cancer progression and relapse. (nih.gov)
• Our study demonstrates that curcumin pretreatment accelerated healing of irradiated wound and could be a substantial therapeutic strategy in the management of irradiated wounds. (hilarispublisher.com)

Oleoresin2

• Genetic Toxicity Evaluation of Turmeric, Oleoresin (Curcumin) in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
• Home » Chemical Effects in Biological Systems (CEBS) » Genetic Toxicity Evaluation of Turmeric, Oleoresin (Curcumin) in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)

Demethoxycurcumin1

• Curcumin Description: Turmeric is produced by grinding the rhizomes of the perennial herb.The colorings responsible for the bright yellow hue of turmeric are the pigments curcumin,demethoxycurcumin a. (21food.com)

20231

• 2023). Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis. (news-medical.net)

Antioxidant3

• Abstract: Curcumin, a polyphenol isolated from the plant turmeric, is recognized for its antioxidant, anti-inflammatory and anti-tumorigenic bioactivities. (nih.gov)
• Curcumin has antioxidant and anti-cancer properties, and it has also been used as a radiosensitizer. (jcancer.org)
• Biochemical and gene chip analysis indicated that curcumin at concentrations up to 1 muM propagates its effect via antioxidant-independent mechanisms associated with the phosphorylation-ubiquitin-proteasome pathway. (nih.gov)

Extract9

• Hongda USP Curcumin Extraction Plant Curcumin Extract 95% New Exhibtion Welcome your visit at STAND 7H52 in FI Europe&Ni Dec. 3th-5th. (21food.com)
• Product: Curcumin ,Turmeric Root extract Source Of Plant : Turmeric Root Description : Curcumin is extracted from turmeric root, is regarded as the most development value of edible natural pigment by. (21food.com)
• 1.Pharmaceutical raw materials curcumin extract 95% 2. (21food.com)
• Pharmaceutical raw materials 3.100% natural Curcumin Pharmaceutical raw materials curcumin extract 95% Turmeric Curcumin Powder is a kind of ora. (21food.com)
• Turmeric extract supplier, curcumin 95% powder, curcumin 95% powder extract. (21food.com)
• These statements are based on a human study of NovaSOL® curcumin in comparison with native curcumin extract, using an object measure (metabolite analysis). (solgar.com)
• Based on a human study of NovaSOL® curcumin in comparison with native curcumin extract, using an objective measure (metabolite analysis). (solgar.com)
• Support your wellness journey today with Solgar® Full Spectrum Curcumin Liquid Extract Softgels. (solgar.com)
• Vancouver, CANADA, October 5, 2016 - New biomedical research released today jointly by The Rhema Group and Biologic Pharmamedical, has shown that a trace component of the standard curcumin extract, bisdemethoxycurcumin (BDMC), is proven to be up to 7X more potent on a key anti-inflammatory target than the curcumin extract itself. (totalhealthmagazine.com)

Extracts1

• This new pointed pharmacological research on curcumin reveals that although BDMC exists in extremely low concentrations in standardized curcumin extracts -between 0.5 to 1.5 per cent - it can play a key role in therapy if it is raised to 30 per cent. (totalhealthmagazine.com)

Signaling pathway2

• LMU researchers have identified a signaling pathway via which curcumin can suppress the metastasis of colorectal cancer cells. (news-medical.net)
• A team led by Heiko Hermeking, Professor of Experimental and Molecular Pathology at LMU, has now demonstrated in cell cultures and in a mouse model that curcumin, a natural substance found in the spice turmeric, can bridge this silenced protective mechanism by activating an alternative, specific signaling pathway that induces the expression of miR-34. (news-medical.net)

Mice6

• We have discovered a novel, previously unrecognized oxidative transformation of curcumin, and we have detected abundant levels of the oxidative metabolites in plasma and intestinal mucosa after oral administration of curcumin to mice. (nih.gov)
• When injected proximal to the sciatic nerve in mice via intramuscular (i.m.) injection, ELP-curcumin conjugates underwent a thermally triggered soluble-insoluble phase transition, leading to in situ formation of a depot that released curcumin over 4days post-injection and decreased plasma AUC 7-fold. (duke.edu)
• A full-thickness dermal excision wound was created on the shaved dorsum of mice orally administered or not with 100 mg/kg body weight of curcumin before partial body exposure to 10, 20 or 40 Gy given as 2 Gy/day for 5, 10 or 20 days. (hilarispublisher.com)
• Fractionated irradiation of mice caused a dose dependent delay in the wound contraction and prolonged wound healing time, whereas curcumin administration prior to fractionated irradiation resulted in a significant rise in the wound contraction and curtailed mean wound healing time. (hilarispublisher.com)
• Fractionated irradiation reduced the synthesis of collagen, DNA and nitric oxide in the regenerating wounds at different post-irradiation times, whereas treatment of mice with curcumin before irradiation elevated the synthesis of collagen, DNA and nitric oxide significantly. (hilarispublisher.com)
• Curcumin was administered chronically to aged Tg2576 mice, or acutely LPS treated wild type mice. (nih.gov)

Boosts3

• The figure above shows how it apparently does work: curcumin boosts the production of the anti-suicide protein XIAP during the R10 phase. (ergo-log.com)
• Curcumin has an anabolic/anticatabolic effect in muscle tissue, it inhibits the conversion of amino acids into energy, it protects the prostate against androgens, boosts the blood vessel widening effect of NO - and may also possibly slow the rate at which your hair turns grey. (ironmagazine.com)
• How curcumin boosts the effects of exercise the Japanese researchers don't know. (ironmagazine.com)

Natural pigment1

• Curcumin, the natural pigment that gives the spice turmeric its yellow color, has increasingly come under the scientific spotlight in recent years, with studies investigating its potential health benefits. (nutraingredients-usa.com)

Mechanism4

• Specifically, we will analyze the mechanism of inhibition of reduced and oxidized IKKß by electrophilic and nucleophilic curcumin metabolites, the mechanism of induction of DNA cleavage by topoisomerase II, and protein and DNA adduct formation by the quinone methide intermediate. (nih.gov)
• In Specific Aim 2 we will identify the products and intermediates of oxidative transformation of curcumin and determine their mechanism of formation. (nih.gov)
• The figure below shows that curcumin had no effect on the uibiquitin-proteasome complex, a mechanism that steers the muscle-protein breakdown machinery. (ergo-log.com)
• This enhancement fortifies the mechanism by which curcumin can inhibit nuclear, MSK1, a facilitative kinase protein central to the inflammatory process," says Cavaleri. (totalhealthmagazine.com)

Colorectal cancer3

• Using genetically-modified human colorectal cancer cell lines, the researchers have now demonstrated that curcumin increases the production of so-called reactive oxygen species (ROS) in tumor cells. (news-medical.net)
• We were also able to confirm in our mouse model that the curcumin-induced expression of miR-34 suppresses the metastasis of colorectal cancer cells into the lung. (news-medical.net)
• Curcumin suppresses metastasis in colorectal cancer (CRC) by modulating crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment, at least in part by the mediation of transforming growth factor-β (TGF-β) and epithelial-mesenchymal transition (EMT) [ 11 ]. (jcancer.org)

Concentrations1

• The biochemical test results showed that the urea (Ur), creatinine (Cr), uric acid (UA), inorganic phosphorus and Ca2+ concentrations in urine decreased after being treated with curcumin. (bvsalud.org)

Inflammation2

• Hidden deep in the plant's bright yellow roots is an extraordinarily powerful compound called curcumin that has the unique ability to block an enzyme that causes inflammation, while combatting free radical damage to highly sensitive vital organs like your brain and heart. (bartonpublishing.com)
• In both the acute (LPS) and chronic inflammation model (Tg2576), TC and curcumin similarly reduced interleukin-1β. (nih.gov)

20191

• 2019 Curcumin is from Jiang Ke, Araceae in the roots of cert. (21food.com)

BDNF3

• Curcumin has been shown, in preclinical and animal studies, to promote the activity of brain-derived neurotropic factor (BDNF) , a vital signaling factor that promotes the growth and strengthening of nerve networks vital to retaining cognitive and memory skills. (lifeextension.com)
• Curcumin stimulates production of an essential growth factor, BDNF , that promotes new connections ( neuronal plasticity ) between brain cells. (lifeextension.com)
• Interestingly, the group also observed a similar dose-dependent decrease of BDNF and Cox-2 in the spinal cord after curcumin treatment. (epigenie.com)

Induce2

• There were already indications in the literature that curcumin can induce miR-34, but there was no systematic investigation of the phenomenon before now. (news-medical.net)
• Researchers are finding that curcumin can reduce anxiety/depression, promote neurite growth and induce brain plasticity. (lifeextension.com)

Derivative1

• The major final product is a dioxygenated cyclopentadione derivative of curcumin. (nih.gov)

Supplements4

• If taking with just water, using a bioavailability-enhanced formula may increase the absorption (see the Best Way to Take Curcumin and Turmeric Supplements for details). (consumerlab.com)
• Turmeric/curcumin supplements are generally safe, but gastrointestinal side effects may occur with higher doses and they can cause problems for people with gallbladder disease, kidney stones, or those taking blood-thinning or blood-sugar-lowering medications. (consumerlab.com)
• I also began to search for organic superfood supplements - one thing led to another, and I found Turmeric Curcumin Plus, one that would eventually change my life for the better. (adustyframe.com)
• There's no healthy aging without a healthy brain, so brain-protecting curcumin should be on every serious person's "A-list" of essential supplements. (lifeextension.com)

Capsules1

• One 40mg Solgar Licaps™ = dozens of 100mg curcumin capsules! (solgar.com)

Complex3

• Bioavailability is enhanced with a curcumin-phosphatidylcholine complex. (greenmedinfo.com)
• Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin. (greenmedinfo.com)
• Phospholipid complex of the natural compound curcumin was prepared in order to improve its bioavailability. (greenmedinfo.com)

Efficacy1

• Novel curcumin formulations may also be used to reverse drug resistance, eradicate the total cancer cell mass and improve the anticarcinogenic efficacy of the current anti-hormonal and chemotherapeutic treatments for patients with various aggressive and lethal cancers. (nih.gov)

Inflammatory4

• Curcumin is a potent anti-inflammatory herb that has been demonstrated to protect against a host of degenerative conditions. (lifeextension.com)
• They speculate that curcumin blocks the effect of the inflammatory protein TNF-alpha, but have no data to back this up. (ironmagazine.com)
• Curcumin is a major component of turmeric with known anti-inflammatory and anti-oxidative effects. (ironmagazine.com)
• Curcumin (CUR) is the main ingredient of turmeric, has been confirmed to possess anti-inflammatory and anti-oxidative characteristics. (scialert.net)

Protein6

• Curcumin treatment increased muscle XIAP protein levels during reloading above basal levels", the researchers conclude. (ergo-log.com)
• Curcumin attenuates the malignant potential of glioblastoma stem cells by induction of reactive oxygen species (ROS) and activation of the mitogen-activated protein kinase (MAPK) pathway [ 10 ]. (jcancer.org)
• These data indicate that the dienone bridge present in curcumin, but not in TC, is necessary to reduce plaque deposition and protein oxidation in an Alzheimer's model. (nih.gov)
• Targeted Delivery of Curcumin Rescues Endoplasmic Reticulum-Retained Mutant NOX2 Protein and Avoids Leukocyte Apoptosis. (nih.gov)
• CSE caused a reduction in HDAC2 protein expression that was restored by curcumin. (nih.gov)
• This decrease in HDAC2 protein expression was reversed by curcumin even in the presence of cycloheximide, a protein synthesis inhibitor. (nih.gov)

Significantly reduced1

• In addition, reverse transcription polymerase chain reaction (PCR) detection and immunohistochemical results indicated that the osteopontin (OPN) in the kidney was significantly reduced after curcumin treatment. (bvsalud.org)

Specifically1

• Specifically, curcumin and its derivatives protect DNA against oxidative damage induced by reactive oxygen species. (needs.com)

Tumor2

• In addition, curcumin made tumor cells more sensitive to the chemotherapeutic substance 5-FU by means of miR-34. (news-medical.net)
• Finally, it was demonstrated by reverse transcription-quantitative polymerase chain reaction assay and wound healing assay that curcumin could enhance radiosensitization of NPC cell lines via mediating regulation of tumor stem-like cells by the 'hsa_circRNA_102115'-'hsa-miR-335-3p'-'MAPK1' interaction network. (jcancer.org)

Anticancer1

• Purpose: Curcumin is known for its anticancer and migrastatic activity in various cancers, including breast cancer. (mdpi.com)

Rats1

• Methods: Thirty male rats were divided into normal control, model, positive (10% potassium citrate), Cur-10 (10 mg/kg curcumin) and Cur-20 (20 mg/kg curcumin) groups. (bvsalud.org)

Researchers4

• This process of rejuvenation is helped not only by training, but also by taking curcumin [structural formula shown here], researchers at the University of Tsukuba in Japan discovered. (ironmagazine.com)
• Japanese researchers recently published studies in which they studied the effect of curcumin on the blood vessels of post-menopausal women. (ironmagazine.com)
• On this occasion the researchers also had a group of women that took curcumin but did not exercise. (ironmagazine.com)
• Curcumin ingestion alone increases arterial compliance in postmenopausal women", the researchers conclude. (ironmagazine.com)

Findings1

• New research findings show that curcumin can reduce anxiety and depression. (lifeextension.com)

Health supplement1

• Turmeric Curcumin Plus is just one of many health supplement products manufactured by Vita Balance, Inc., a US-based company. (adustyframe.com)

Anabolic1

• But if this animal study confirms that curcumin really has anabolic qualities, we won't be complaining. (ergo-log.com)

Vascular2

• Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. (ironmagazine.com)
• Histological examination revealed a reduction in the collagen deposition, fibroblast and vascular densities after fractionated irradiation, whereas curcumin pretreatment inhibited this decline significantly. (hilarispublisher.com)

Cognitive2

• Turmeric/curcumin may improve cognitive function in healthy older adults, but little benefit has been found in people with Alzheimer's disease. (consumerlab.com)
• From cognitive capabilities to dynamic movements, Turmeric Curcumin Plus guarantees that you'll still be able to live your best life even as you grow in age. (adustyframe.com)

Found3

• With curcumin, we've found a substance with which we could intervene in the signal cascade beneath p53 by activating miR-34,' says Hermeking. (news-medical.net)
• 22 More recently, curcumin has been found to favorably affect two critical processes that are at the core of learning and memory. (lifeextension.com)
• A research team from China investigated how curcumin works to treat neuropathic pain, and found that it prevents the activity regulated expression of certain pain causing genes. (epigenie.com)

Prominent1

• The oxidative transformation of curcumin is rapid, prominent, and gives rise to novel metabolites via reactive intermediates, including a quinone methide and a spiro-epoxide intermediate. (nih.gov)