A genus of coccidian parasites of the family CRYPTOSPORIDIIDAE, found in the intestinal epithelium of many vertebrates including humans.
A species of parasitic protozoa that infects humans and most domestic mammals. Its oocysts measure five microns in diameter. These organisms exhibit alternating cycles of sexual and asexual reproduction.
Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.
Zygote-containing cysts of sporozoan protozoa. Further development in an oocyst produces small individual infective organisms called SPOROZOITES. Then, depending on the genus, the entire oocyst is called a sporocyst or the oocyst contains multiple sporocysts encapsulating the sporozoites.
A subclass of protozoans commonly parasitic in the epithelial cells of the intestinal tract but also found in the liver and other organs. Its organisms are found in both vertebrates and higher invertebrates and comprise two orders: EIMERIIDA and EUCOCCIDIIDA.
A genus of flagellate intestinal EUKARYOTES parasitic in various vertebrates, including humans. Characteristics include the presence of four pairs of flagella arising from a complicated system of axonemes and cysts that are ellipsoidal to ovoidal in shape.
Deoxyribonucleic acid that makes up the genetic material of protozoa.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Constituent of the 40S subunit of eukaryotic ribosomes. 18S rRNA is involved in the initiation of polypeptide synthesis in eukaryotes.
An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA LAMBLIA. It is spread via contaminated food and water and by direct person-to-person contact.
The study of parasites and PARASITIC DISEASES.
A species of parasitic EUKARYOTES that attaches itself to the intestinal mucosa and feeds on mucous secretions. The organism is roughly pear-shaped and motility is somewhat erratic, with a slow oscillation about the long axis.
Determination of parasite eggs in feces.
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
Ribonucleic acid in protozoa having regulatory and catalytic roles as well as involvement in protein synthesis.
Means or process of supplying water (as for a community) usually including reservoirs, tunnels, and pipelines and often the watershed from which the water is ultimately drawn. (Webster, 3d ed)
A genus of coccidian parasites in the family EIMERIIDAE. Cyclospora cayetanensis is pathogenic in humans, probably transmitted via the fecal-oral route, and causes nausea and diarrhea.
Infections with unicellular organisms formerly members of the subkingdom Protozoa.
A phylum of unicellular parasitic EUKARYOTES characterized by the presence of complex apical organelles generally consisting of a conoid that aids in penetrating host cells, rhoptries that possibly secrete a proteolytic enzyme, and subpellicular microtubules that may be related to motility.
Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Proteins found in any species of protozoan.
Contamination of bodies of water (such as LAKES; RIVERS; SEAS; and GROUNDWATER.)
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Immunoglobulins produced in a response to PROTOZOAN ANTIGENS.
Any of several processes in which undesirable impurities in water are removed or neutralized; for example, chlorination, filtration, primary treatment, ion exchange, and distillation. It includes treatment of WASTE WATER to provide potable and hygienic water in a controlled or closed environment as well as provision of public drinking water supplies.
Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.
Diseases of non-human animals that may be transmitted to HUMANS or may be transmitted from humans to non-human animals.
Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.
Water containing no significant amounts of salts, such as water from RIVERS and LAKES.
The functional hereditary units of protozoa.
The presence of bacteria, viruses, and fungi in water. This term is not restricted to pathogenic organisms.
Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.
Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals.
The product of meiotic division of zygotes in parasitic protozoa comprising haploid cells. These infective cells invade the host and undergo asexual reproduction producing MEROZOITES (or other forms) and ultimately gametocytes.
DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.
A form of fluorescent antibody technique utilizing a fluorochrome conjugated to an antibody, which is added directly to a tissue or cell suspension for the detection of a specific antigen. (Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
A genus of protozoan parasites found in the intestines of birds, amphibians, reptiles, and mammals, including man. The oocysts produce two sporocysts, each with four sporozoites. Many species are parasitic in wild and domestic animals.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Refuse liquid or waste matter carried off by sewers.
A genus of parasitic FUNGI in the family Enterocytozoonidae, which infects humans. Enterocytozoon bieneusi has been found in the intestines of patients with AIDS.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumor cells from the marrow (BONE MARROW PURGING) of patients who are to undergo autologous bone marrow transplantation.
A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A genus of protozoan parasites of the subclass COCCIDIA. Various species are parasitic in the epithelial cells of the liver and intestines of man and other animals.
An oligosaccharide antibiotic produced by various STREPTOMYCES.
The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.
Large natural streams of FRESH WATER formed by converging tributaries and which empty into a body of water (lake or ocean).
Measure of the number of the PARASITES present in a host organism.
The complete genetic complement contained in a set of CHROMOSOMES in a protozoan.
Infection with parasitic protozoa of the genus CYCLOSPORA. It is distributed globally and causes a diarrheal illness. Transmission is waterborne.
Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
The relationships of groups of organisms as reflected by their genetic makeup.
Activity engaged in for pleasure.
Infections with FUNGI of the phylum MICROSPORIDIA.
Animals which have become adapted through breeding in captivity to a life intimately associated with humans. They include animals domesticated by humans to live and breed in a tame condition on farms or ranches for economic reasons, including LIVESTOCK (specifically CATTLE; SHEEP; HORSES; etc.), POULTRY; and those raised or kept for pleasure and companionship, e.g., PETS; or specifically DOGS; CATS; etc.
Substances that are destructive to protozoans.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Genes, found in both prokaryotes and eukaryotes, which are transcribed to produce the RNA which is incorporated into RIBOSOMES. Prokaryotic rRNA genes are usually found in OPERONS dispersed throughout the GENOME, whereas eukaryotic rRNA genes are clustered, multicistronic transcriptional units.
A phylum of fungi comprising minute intracellular PARASITES with FUNGAL SPORES of unicellular origin. It has two classes: Rudimicrosporea and MICROSPOREA.
Drugs used to treat or prevent parasitic infections.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Animals kept by humans for companionship and enjoyment, as opposed to DOMESTIC ANIMALS such as livestock or farm animals, which are kept for economic reasons.
The presence of parasites in food and food products. For the presence of bacteria, viruses, and fungi in food, FOOD MICROBIOLOGY is available.
Infection with parasitic protozoa of the genus ISOSPORA, producing intestinal disease. It is caused by ingestion of oocysts and can produce tissue cysts.
An agency in the Executive Branch of the Federal Government. It was created as an independent regulatory agency responsible for the implementation of federal laws designed to protect the environment. Its mission is to protect human health and the ENVIRONMENT.
The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.

Identification of Cryptosporidium felis in a cow by morphologic and molecular methods. (1/603)

Apicomplexan Cryptosporidium parasites infect a wide range of vertebrate hosts. While some species are limited to a single host group, such as Cryptosporidium baileyi, which infects chickens, other species of this genus, such as C. parvum, infect a wide range of mammalian species from mice to humans. During an investigation of Cryptosporidium infection in cattle on a farm in northern Poland, we identified an infection caused by C. felis, in addition to known infections with C. muris and C. parvum. This new infection was identified based on the size of the oocysts (mean size, 4.3 +/- 0.4 micrometer; range, 3.5 to 5.0 micrometer), as well as by analysis of the molecular sequence of the variable region of the small-subunit rRNA. This finding demonstrates the complex host specificity and circulation in the environment of Cryptosporidium species.  (+info)

Phylogenetic analysis of Cryptosporidium parasites based on the small-subunit rRNA gene locus. (2/603)

Biological data support the hypothesis that there are multiple species in the genus Cryptosporidium, but a recent analysis of the available genetic data suggested that there is insufficient evidence for species differentiation. In order to resolve the controversy in the taxonomy of this parasite genus, we characterized the small-subunit rRNA genes of Cryptosporidium parvum, Cryptosporidium baileyi, Cryptosporidium muris, and Cryptosporidium serpentis and performed a phylogenetic analysis of the genus Cryptosporidium. Our study revealed that the genus Cryptosporidium contains the phylogenetically distinct species C. parvum, C. muris, C. baileyi, and C. serpentis, which is consistent with the biological characteristics and host specificity data. The Cryptosporidium species formed two clades, with C. parvum and C. baileyi belonging to one clade and C. muris and C. serpentis belonging to the other clade. Within C. parvum, human genotype isolates and guinea pig isolates (known as Cryptosporidium wrairi) each differed from bovine genotype isolates by the nucleotide sequence in four regions. A C. muris isolate from cattle was also different from parasites isolated from a rock hyrax and a Bactrian camel. Minor differences were also detected between C. serpentis isolates from snakes and lizards. Based on the genetic information, a species- and strain-specific PCR-restriction fragment length polymorphism diagnostic tool was developed.  (+info)

Age-dependent resistance to Cryptosporidium muris (strain MCR) infection in golden hamsters and mice. (3/603)

An age-dependent aspect of resistance to Cryptosporidium muris (strain MCR) infection was monitored in Syrian golden hamsters, Mesocricetus auratus, at 1-, 5- and 10-week of age and in ICR mice. Mus musculus, at 3-, 12-, and 15-week of age orally inoculated with a single dose of 2 x 10(6) oocysts, respectively. The prepatent periods for both animals were similar, independent of age, but the patency was significantly longer in younger hamsters (P < 0.001) and a long tendency in younger mice. Hamsters infected at 1-week of age excreted about 10 times higher oocysts than those at 5- and 10-week of age. However, the total oocyst output was similar among mice of different ages. There was a good correlation between the length of the patency and the total oocyst output in hamsters (R = 0.9646), but not in mice (R = 0.4561). The immunogenicity of the parasite to homologous challenge infections was very strong in hamsters and relatively strong in mice. These results indicate that acquired resistance to C. muris infection is age-related and the innate resistance is independent of age of hamsters, and that both innate and acquired resistance, on the contrary, are irrespective of age of mice.  (+info)

False-positive results obtained with the Alexon ProSpecT Cryptosporidium enzyme immunoassay. (4/603)

Cryptosporidium is known to cause diarrhea in immunocompromised patients and is also associated with outbreaks of disease due to food-borne and waterborne parasites. Traditional procedures, involving iodine staining of wet mounts of stool sediments and trichrome staining, lack the sensitivity to detect Cryptosporidium. Special staining procedures, such as the modified acid-fast and safranin stains, are generally employed. Less labor-intensive antigen detection assays have simplified detection; however, careful attention to local epidemiology is important because false-positive tests occur. Here, we report two incidents involving 62 false-positive results obtained with the Alexon ProSpecT Cryptosporidium enzyme immunoassay, which were deemed false-positive based on negative results obtained from extensive microscopic examinations.  (+info)

New cryptosporidium genotypes in HIV-infected persons. (5/603)

Using DNA sequencing and phylogenetic analysis, we identified four distinct Cryptosporidium genotypes in HIV-infected patients: genotype 1 (human), genotype 2 (bovine) Cryptosporidium parvum, a genotype identical to C. felis, and one identical to a Cryptosporidium sp. isolate from a dog. This is the first identification of human infection with the latter two genotypes.  (+info)

Determinants of antibodies to Cryptosporidium infection among gay and bisexual men with HIV infection. (6/603)

A cross-sectional serosurvey for markers of prior Cryptosporidium infection was conducted among homosexual or bisexual males infected with human immunodeficiency virus (HIV); of 262 individuals approached, 236 (90%) agreed to participate. Serological response to two Cryptosporidium antigens was measured using a Western blot assay. The intensity or detection of serological responses to two Cryptosporidium antigens was not associated with CD4 cell counts or tap water consumption. A number of sexual practices were related to increased serological response for only the 27-kDa marker, including having had sex within the past 2 years, having anal sex and having had a larger number of sex partners during the past 2 years. Attending a spa or sauna was related to serological response to both the 27-kDa and 17-kDa markers. Based on these results, activities related to sexual activity appear to be a significant risk factors for prior Cryptosporidium infection.  (+info)

Infectivity to hosts of the endogenous stages of chicken and murine Cryptosporidium. (7/603)

Five groups of 4 mice each were inoculated with 10(6) Cryptosporidium muris oocysts. They were necropsied on days 2, 4, 6, 8 and 10. The stomach mucosa from each group were made into 10% suspension in physiological saline and were orally inoculated to 2 mice each. Recipients given suspension from infected mice on day 6, 8 and 10 shed oocysts from 6, 9 and 6, respectively. Similarly, White Leghorn received 10(6) Cryptosporidium sp. oocysts were killed daily between 1 and 6 days. Recipients given bursa of Fabricius or caecum of donor birds on days 4, 5 and 6 shed oocysts. The endogenous stages of murine and chicken Cryptosporidium were able to infect the appropriate host.  (+info)

Genetic diversity within Cryptosporidium parvum and related Cryptosporidium species. (8/603)

To assess the genetic diversity in Cryptosporidium parvum, we have sequenced the small subunit (SSU) rRNA gene of seven Cryptosporidium spp., various isolates of C. parvum from eight hosts, and a Cryptosporidium isolate from a desert monitor. Phylogenetic analysis of the SSU rRNA sequences confirmed the multispecies nature of the genus Cryptosporidium, with at least four distinct species (C. parvum, C. baileyi, C. muris, and C. serpentis). Other species previously defined by biologic characteristics, including C. wrairi, C. meleagridis, and C. felis, and the desert monitor isolate, clustered together or within C. parvum. Extensive genetic diversities were present among C. parvum isolates from humans, calves, pigs, dogs, mice, ferrets, marsupials, and a monkey. In general, specific genotypes were associated with specific host species. A PCR-restriction fragment length polymorphism technique previously developed by us could differentiate most Cryptosporidium spp. and C. parvum genotypes, but sequence analysis of the PCR product was needed to differentiate C. wrairi and C. meleagridis from some of the C. parvum genotypes. These results indicate a need for revision in the taxonomy and assessment of the zoonotic potential of some animal C. parvum isolates.  (+info)

Word origin:

Cryptosporidium (genus name) is derived from the Greek words "kruptos" (meaning hidden) and "sporos" (meaning seed), referring to the parasite's ability to hide within host cells. The specific species of Cryptosporidium that infect humans is known as C. parvum.

Example sentences:

1. The CDC has reported an outbreak of cryptosporidiosis in a community with a contaminated water supply.
2. The patient was diagnosed with cryptosporidiosis after experiencing severe diarrhea and vomiting for several days.
3. The researchers are studying the effectiveness of antimicrobial medications against cryptosporidiosis in immunocompromised individuals.

Giardiasis is a disease caused by the protozoan parasite Giardia duodenalis, which is found in contaminated water, food, or direct contact with infected individuals. The parasite enters the small intestine and feeds on the mucosal lining, causing inflammation, diarrhea, and abdominal cramps.

Prevalence:

Giardiasis is a common disease worldwide, affecting approximately 500 million people annually, with higher prevalence in developing countries. In the United States, it is estimated that over 1.5 million people are infected each year, with the highest incidence rates found among children and travelers to endemic areas.

Symptoms:

The symptoms of giardiasis can vary in severity but typically include:

* Diarrhea (sometimes bloody)
* Abdominal cramps
* Weight loss
* Fatigue
* Nausea and vomiting
* Fever
* Headache

In some cases, the infection can lead to more severe complications such as:

* Malabsorption (deficiency of essential nutrients)
* Inflammation of the intestine
* Rectal prolapse

Diagnosis:

The diagnosis of giardiasis is based on a combination of clinical symptoms, laboratory tests, and medical history. The most common diagnostic techniques include:

* Microscopic examination of stool samples for the presence of Giardia eggs or trophozoites
* Enzyme-linked immunosorbent assay (ELISA) to detect antigens or antibodies against Giardia in stool or blood samples
* Polymerase chain reaction (PCR) to detect the parasite's DNA in stool samples

Treatment:

The treatment of giardiasis typically involves the use of antiparasitic drugs, such as metronidazole or tinidazole. These medications are effective against the parasite and can be administered orally or intravenously, depending on the severity of the infection. The duration of treatment varies depending on the individual case, but it is generally between 5-10 days.

Prevention:

Preventing giardiasis involves avoiding exposure to contaminated water or food sources. Some measures that can be taken to prevent the infection include:

* Avoiding consumption of untreated water, especially when traveling to areas with poor sanitation
* Avoiding contact with people who have diarrhea or are infected with Giardia
* Properly storing and cooking food to kill any parasites that may be present
* Avoiding raw or undercooked meat, especially pork and wild game
* Washing hands frequently, especially before eating or preparing food

It is important to note that giardiasis can be a recurring infection, so it is important to take preventive measures consistently.

There are several types of diarrhea, including:

1. Acute diarrhea: This type of diarrhea is short-term and usually resolves on its own within a few days. It can be caused by a viral or bacterial infection, food poisoning, or medication side effects.
2. Chronic diarrhea: This type of diarrhea persists for more than 4 weeks and can be caused by a variety of conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or celiac disease.
3. Diarrhea-predominant IBS: This type of diarrhea is characterized by frequent, loose stools and abdominal pain or discomfort. It can be caused by a variety of factors, including stress, hormonal changes, and certain foods.
4. Infectious diarrhea: This type of diarrhea is caused by a bacterial, viral, or parasitic infection and can be spread through contaminated food and water, close contact with an infected person, or by consuming contaminated food.

Symptoms of diarrhea may include:

* Frequent, loose, and watery stools
* Abdominal cramps and pain
* Bloating and gas
* Nausea and vomiting
* Fever and chills
* Headache
* Fatigue and weakness

Diagnosis of diarrhea is typically made through a physical examination, medical history, and laboratory tests to rule out other potential causes of the symptoms. Treatment for diarrhea depends on the underlying cause and may include antibiotics, anti-diarrheal medications, fluid replacement, and dietary changes. In severe cases, hospitalization may be necessary to monitor and treat any complications.

Prevention of diarrhea includes:

* Practicing good hygiene, such as washing hands frequently and thoroughly, especially after using the bathroom or before preparing food
* Avoiding close contact with people who are sick
* Properly storing and cooking food to prevent contamination
* Drinking safe water and avoiding contaminated water sources
* Avoiding raw or undercooked meat, poultry, and seafood
* Getting vaccinated against infections that can cause diarrhea

Complications of diarrhea can include:

* Dehydration: Diarrhea can lead to a loss of fluids and electrolytes, which can cause dehydration. Severe dehydration can be life-threatening and requires immediate medical attention.
* Electrolyte imbalance: Diarrhea can also cause an imbalance of electrolytes in the body, which can lead to serious complications.
* Inflammation of the intestines: Prolonged diarrhea can cause inflammation of the intestines, which can lead to abdominal pain and other complications.
* Infections: Diarrhea can be a symptom of an infection, such as a bacterial or viral infection. If left untreated, these infections can lead to serious complications.
* Malnutrition: Prolonged diarrhea can lead to malnutrition and weight loss, which can have long-term effects on health and development.

Treatment of diarrhea will depend on the underlying cause, but may include:

* Fluid replacement: Drinking plenty of fluids to prevent dehydration and replace lost electrolytes.
* Anti-diarrheal medications: Over-the-counter or prescription medications to slow down bowel movements and reduce diarrhea.
* Antibiotics: If the diarrhea is caused by a bacterial infection, antibiotics may be prescribed to treat the infection.
* Rest: Getting plenty of rest to allow the body to recover from the illness.
* Dietary changes: Avoiding certain foods or making dietary changes to help manage symptoms and prevent future episodes of diarrhea.

It is important to seek medical attention if you experience any of the following:

* Severe diarrhea that lasts for more than 3 days
* Diarrhea that is accompanied by fever, blood in the stool, or abdominal pain
* Diarrhea that is severe enough to cause dehydration or electrolyte imbalances
* Diarrhea that is not responding to treatment

Prevention of diarrhea includes:

* Good hand hygiene: Washing your hands frequently, especially after using the bathroom or before preparing food.
* Safe food handling: Cooking and storing food properly to prevent contamination.
* Avoiding close contact with people who are sick.
* Getting vaccinated against infections that can cause diarrhea, such as rotavirus.

Overall, while diarrhea can be uncomfortable and disruptive, it is usually a minor illness that can be treated at home with over-the-counter medications and plenty of fluids. However, if you experience severe or persistent diarrhea, it is important to seek medical attention to rule out any underlying conditions that may require more formal treatment.

Some common types of protozoan infections include:

1. Malaria: Caused by the Plasmodium parasite, which is transmitted through the bite of an infected mosquito.
2. Giardiasis: Caused by the Giardia parasite, which can be found in contaminated food and water or spread through close contact with an infected person.
3. Amoebiasis: Caused by the Entamoeba parasite, which can infect the intestines and cause symptoms such as diarrhea and abdominal pain.
4. Toxoplasmosis: Caused by the Toxoplasma parasite, which can be spread through contact with contaminated soil or cat feces.
5. Cryptosporidiosis: Caused by the Cryptosporidium parasite, which can be found in contaminated water and can cause symptoms such as diarrhea and stomach cramps.

Protozoan infections are typically treated with antiparasitic medications, and early diagnosis and treatment can help prevent complications and improve outcomes.

Cattle diseases refer to any health issues that affect cattle, including bacterial, viral, and parasitic infections, as well as genetic disorders and environmental factors. These diseases can have a significant impact on the health and productivity of cattle, as well as the livelihoods of farmers and ranchers who rely on them for their livelihood.

Types of Cattle Diseases

There are many different types of cattle diseases, including:

1. Bacterial diseases, such as brucellosis, anthrax, and botulism.
2. Viral diseases, such as bovine viral diarrhea (BVD) and bluetongue.
3. Parasitic diseases, such as heartwater and gapeworm.
4. Genetic disorders, such as polledness and cleft palate.
5. Environmental factors, such as heat stress and nutritional deficiencies.

Symptoms of Cattle Diseases

The symptoms of cattle diseases can vary depending on the specific disease, but may include:

1. Fever and respiratory problems
2. Diarrhea and vomiting
3. Weight loss and depression
4. Swelling and pain in joints or limbs
5. Discharge from the eyes or nose
6. Coughing or difficulty breathing
7. Lameness or reluctance to move
8. Changes in behavior, such as aggression or lethargy

Diagnosis and Treatment of Cattle Diseases

Diagnosing cattle diseases can be challenging, as the symptoms may be similar for different conditions. However, veterinarians use a combination of physical examination, laboratory tests, and medical history to make a diagnosis. Treatment options vary depending on the specific disease and may include antibiotics, vaccines, anti-inflammatory drugs, and supportive care such as fluids and nutritional supplements.

Prevention of Cattle Diseases

Preventing cattle diseases is essential for maintaining the health and productivity of your herd. Some preventative measures include:

1. Proper nutrition and hydration
2. Regular vaccinations and parasite control
3. Sanitary living conditions and frequent cleaning
4. Monitoring for signs of illness and seeking prompt veterinary care if symptoms arise
5. Implementing biosecurity measures such as isolating sick animals and quarantining new animals before introduction to the herd.

It is important to work closely with a veterinarian to develop a comprehensive health plan for your cattle herd, as they can provide guidance on vaccination schedules, parasite control methods, and disease prevention strategies tailored to your specific needs.

Conclusion
Cattle diseases can have a significant impact on the productivity and profitability of your herd, as well as the overall health of your animals. It is essential to be aware of the common cattle diseases, their symptoms, diagnosis, treatment, and prevention methods to ensure the health and well-being of your herd.

By working closely with a veterinarian and implementing preventative measures such as proper nutrition and sanitary living conditions, you can help protect your cattle from disease and maintain a productive and profitable herd. Remember, prevention is key when it comes to managing cattle diseases.

Some common types of intestinal diseases, parasitic include:

1. Amoebiasis: This is an infection caused by the amoeba Entamoeba histolytica, which can cause diarrhea, abdominal pain, and fever.
2. Giardiasis: This is an infection caused by the parasite Giardia duodenalis, which can cause diarrhea, abdominal cramps, and weight loss.
3. Cryptosporidiosis: This is an infection caused by the parasite Cryptosporidium parvum, which can cause diarrhea, abdominal pain, and fever.
4. Isosporiasis: This is an infection caused by the parasite Isospora belli, which can cause diarrhea, abdominal cramps, and weight loss.
5. Tapeworm infections: These are infections caused by tapeworms, such as Taenia saginata (beef tapeworm) and Dipylidium caninum (dog tapeworm), which can cause abdominal pain, diarrhea, and weight loss.
6. Strongyloidiasis: This is an infection caused by the parasite Strongyloides stercoralis, which can cause diarrhea, abdominal pain, and fatigue.

Intestinal diseases, parasitic can be diagnosed through a combination of physical examination, medical history, and laboratory tests such as stool samples or blood tests. Treatment depends on the specific type of infection and may include antiparasitic medications, anti-diarrheal medications, and supportive care to manage symptoms.

Zoonoses (zoonosis) refers to infectious diseases that can be transmitted between animals and humans. These diseases are caused by a variety of pathogens, including bacteria, viruses, parasites, and fungi, and can be spread through contact with infected animals or contaminated animal products.

Examples of Zoonoses

Some common examples of zoonoses include:

1. Rabies: a viral infection that can be transmitted to humans through the bite of an infected animal, typically dogs, bats, or raccoons.
2. Lyme disease: a bacterial infection caused by Borrelia burgdorferi, which is spread to humans through the bite of an infected blacklegged tick (Ixodes scapularis).
3. Toxoplasmosis: a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with contaminated cat feces or undercooked meat.
4. Leptospirosis: a bacterial infection caused by Leptospira interrogans, which is spread to humans through contact with contaminated water or soil.
5. Avian influenza (bird flu): a viral infection that can be transmitted to humans through contact with infected birds or contaminated surfaces.

Transmission of Zoonoses

Zoonoses can be transmitted to humans in a variety of ways, including:

1. Direct contact with infected animals or contaminated animal products.
2. Contact with contaminated soil, water, or other environmental sources.
3. Through vectors such as ticks, mosquitoes, and fleas.
4. By consuming contaminated food or water.
5. Through close contact with an infected person or animal.

Prevention of Zoonoses

Preventing the transmission of zoonoses requires a combination of personal protective measures, good hygiene practices, and careful handling of animals and animal products. Some strategies for preventing zoonoses include:

1. Washing hands frequently, especially after contact with animals or their waste.
2. Avoiding direct contact with wild animals and avoiding touching or feeding stray animals.
3. Cooking meat and eggs thoroughly to kill harmful bacteria.
4. Keeping pets up to date on vaccinations and preventative care.
5. Avoiding consumption of raw or undercooked meat, particularly poultry and pork.
6. Using insect repellents and wearing protective clothing when outdoors in areas where vectors are prevalent.
7. Implementing proper sanitation and hygiene practices in animal housing and husbandry.
8. Implementing strict biosecurity measures on farms and in animal facilities to prevent the spread of disease.
9. Providing education and training to individuals working with animals or in areas where zoonoses are prevalent.
10. Monitoring for and reporting cases of zoonotic disease to help track and control outbreaks.

Conclusion

Zoonoses are diseases that can be transmitted between animals and humans, posing a significant risk to human health and animal welfare. Understanding the causes, transmission, and prevention of zoonoses is essential for protecting both humans and animals from these diseases. By implementing appropriate measures such as avoiding contact with wild animals, cooking meat thoroughly, keeping pets up to date on vaccinations, and implementing proper sanitation and biosecurity practices, we can reduce the risk of zoonotic disease transmission and protect public health and animal welfare.

Eimeria species are obligate intracellular parasites that infect the epithelial cells lining the intestinal tract of animals, causing damage to the gut mucosa and leading to diarrhea, vomiting, weight loss, and even death. The disease can be acute or chronic, depending on the severity of the infection and the host's immune response.

There are several species of Eimeria that can infect ruminants, with different species affecting different parts of the intestinal tract. For example, Eimeria bovis and Eimeria zuernii infect the caecum and abomasum, respectively, while Eimeria ellipsoidalis and Eimeria falciformis infect the small intestine.

Coccidiosis is typically diagnosed through fecal examination, where the presence of oocysts (eggs) in the feces is indicative of an infection. Treatment options include anticoccidial drugs, which can be administered orally or parenterally, and supportive care to manage symptoms such as diarrhea and dehydration.

Prevention is key to managing coccidiosis, and this includes the use of vaccines, cleanliness and hygiene practices, and controlling the parasite's environmental survival. In some cases, a combination of these methods may be necessary to effectively prevent and control coccidiosis in ruminant populations.

Examples of AROIs include:

1. Pneumocystis pneumonia (PCP): a type of pneumonia caused by the fungus Pneumocystis jirovecii.
2. Tuberculosis (TB): a bacterial infection that can affect the lungs, brain, or other organs.
3. Toxoplasmosis: an infection caused by the parasite Toxoplasma gondii that can affect the brain, eyes, and other organs.
4. Cryptococcosis: a fungal infection that can affect the lungs, brain, or skin.
5. Histoplasmosis: a fungal infection caused by Histoplasma capsulatum that can affect the lungs, skin, and other organs.
6. Aspergillosis: a fungal infection caused by Aspergillus species that can affect the lungs, sinuses, and other organs.
7. Candidiasis: a fungal infection caused by Candida species that can affect the mouth, throat, vagina, or skin.
8. Kaposi's sarcoma: a type of cancer that is caused by the human herpesvirus 8 (HHV-8) and can affect the skin and lymph nodes.
9. Wasting syndrome: a condition characterized by weight loss, fatigue, and diarrhea.
10. Opportunistic infections that can affect the gastrointestinal tract, such as cryptosporidiosis and isosporiasis.

AROIs are a major cause of morbidity and mortality in individuals with HIV/AIDS, and they can be prevented or treated with antimicrobial therapy, supportive care, and other interventions.

Cyclosporiasis is diagnosed through a combination of clinical evaluation and laboratory tests, including polymerase chain reaction (PCR) and microscopic examination of stool samples. Treatment typically involves the use of antiparasitic medications such as trimethoprim-sulfamethoxazole or albendazole.

Prevention measures for cyclosporiasis include proper food handling and preparation practices, as well as avoiding consumption of untreated water. In areas where the infection is common, boiling or chlorination of water can also help reduce the risk of transmission.

In conclusion, cyclosporiasis is a parasitic infection caused by Cyclospora cayetanensis that is transmitted through contaminated food and water. It can cause a range of symptoms including diarrhea, abdominal cramps, nausea, vomiting, and fever. Diagnosis is made through laboratory tests, and treatment typically involves antiparasitic medications. Prevention measures include proper food handling and preparation practices, as well as avoiding consumption of untreated water.

The symptoms of microsporidiosis vary depending on the site of infection and the severity of the disease. In some cases, microsporidiosis may be asymptomatic or present with mild symptoms such as fever, headache, fatigue, and muscle aches. In more severe cases, microsporidiosis can cause significant morbidity and mortality, particularly in individuals with compromised immune systems, such as those living with HIV/AIDS or undergoing immunosuppressive therapy following an organ transplant.

Microsporidiosis is diagnosed through a combination of clinical evaluation, laboratory testing, and histopathological examination of tissue samples. Treatment of microsporidiosis typically involves antimicrobial medications, such as azole antifungals or polyene macrolide antibiotics. In severe cases, surgical intervention may be necessary to remove infected tissues or repair damaged organs.

Preventive measures for microsporidiosis include avoiding exposure to contaminated water or food, practicing good hygiene, and avoiding close contact with individuals who are infected with microsporidia. Vaccines against microsporidia are not available, but research is ongoing to develop effective vaccine candidates.

In summary, microsporidiosis is a disease caused by microsporidia that can affect various parts of the body and cause a range of symptoms. Diagnosis and treatment of microsporidiosis are challenging due to the difficulty in identifying the parasite and the lack of effective treatments. Prevention of microsporidiosis primarily relies on avoiding exposure to contaminated sources and practicing good hygiene.

The infection is caused by ingesting contaminated food or water that contains the oocysts of the parasite. The oocysts then sporulate in the intestine and produce mature trophozoites, which penetrate the intestinal walls and cause inflammation.

Isosporiasis is diagnosed by examining stool samples for the presence of the parasite's oocysts or by identifying the characteristic morphology of the trophozoites in a biopsy specimen. Treatment typically involves antiparasitic drugs such as trimethoprim-sulfamethoxazole or pentavalent antimonials.

Isosporiasis is a rare disease in developed countries but is more common in resource-poor settings where sanitation and hygiene are poor. Prevention measures include improving access to clean water, promoting proper hygiene practices, and reducing the risk of food contamination.

... of Cryptosporidium. Membranes and bag- and cartridge-filter products remove Cryptosporidium specifically. Cryptosporidium is ... "Update on Cryptosporidium spp.: highlights from the Seventh International Giardia and Cryptosporidium Conference". Parasite. 27 ... Wikimedia Commons has media related to Cryptosporidium. CryptoDB: The Cryptosporidium Genome Resource Portal: Biology (Articles ... A number of Cryptosporidium species infect mammals. In humans, the main causes of disease are C. parvum and C. hominis ( ...
Genetic Diversity of Cryptosporidium spp. in Captive Reptiles Lihua Xiao, Una M. Ryan, Thaddeus K. Graczyk, Josef Limor, Lixia ... Cryptosporidium Infection in a colony of Leopard Geckos, Eublepharis macularius. Rob L. Coke, DVM, Timothy E. Tristan. 1998. ... Cryptosporidium varanii (syn. C. saurophilum) is a protozoal parasite that infects the gastrointestinal tract of lizards.C. ... Unlike Cryptosporidium serpentis (that predominately infects snakes), C. varanii does not colonize the stomach, but rather the ...
... is a parasite which infects amphibians. The oocysts have an irregular, shape (subspherical to ... Certad, G; Osman, M; Benamrouz, S (2016). "Chapter 20: Pathogenesis of Cryptosporidium in humans". In Singh, SK (ed.). Human ... 5.2.1: Anura". In Cacciò, SM; Widmer, G (eds.). Cryptosporidium: parasite and disease. Vienna: Springer Vienna. p. 239. ISBN ... "New species of Cryptosporidium Tyzzer, 1907 (Apicomplexa) from amphibian host: morphology, biology and phylogeny". Folia ...
... is a species of coccidium, first isolated from the gastric glands of the common mouse.Cryptosporidium ... Cryptosporidium muris infects dogs, rabbits, lambs, cats, humans, and non-human primates. This type of cryptosporidium infects ... McDonald V, Deer R, Uni S, Iseki M, Bancroft GJ (1992). "Immune responses to Cryptosporidium muris and Cryptosporidium parvum ... Also making sure to practice good hygiene improves the risks of not contracting Cryptosporidium. Cryptosporidium muris has ...
... , along with Cryptosporidium parvum, is among the medically important Cryptosporidium species. It is an ... Cryptosporidium infections are large contributors of child death and illness in heavily affected areas, yet low importance has ... The different cryptosporidium species share nearly identical morphological features, so differentiation is only seen at the ... The life cycle of Cryptosporidium hominis is similar to that of others of the genus with infective sporozoites from ingested ...
... is one of several species that cause cryptosporidiosis, a parasitic disease of the mammalian intestinal ... Deng, M.; Lancto, C. A.; Abrahamsen, M. S. (2004). "Cryptosporidium parvum regulation of human epithelial cell gene expression ... September 2000). "Mediation of Cryptosporidium parvum Infection In Vitro by Mucin-Like Glycoproteins Defined by a Neutralizing ... October 1998). "A novel multi-domain mucin-like glycoprotein of Cryptosporidium parvum mediates invasion". Mol. Biochem. ...
Mammal associated Cryptosporidium, such as C. parvum and C. muris have been found in the gastrointestinal tracts of snakes (due ... Cryptosporidium serpentis is a protozoal parasite that infects the gastrointestinal tract of snakes. Sporated oocysts of C. ... Unlike mammalian Cryptosporidium - that is usually self-limiting - C. serpentis remains chronic and in most cases, eventually ... "Molecular Identification of Cryptosporidium Species from Pet Snakes in Thailand." The Korean journal of parasitology vol. 54,4 ...
Giardia lamblia and Cryptosporidium spp., both of which cause diarrhea (see giardiasis and cryptosporidiosis) are common ... Of note, Cryptosporidium oocysts, likely Cyclospora species, Ascaris eggs are extremely resistant to halogens and field ... Most filters of this kind remove most bacteria and protozoa, such as Cryptosporidium and Giardia lamblia, but not viruses ... Neither chlorine (e.g., bleach) nor iodine alone is considered completely effective against Cryptosporidium, although they are ...
"General Information for the Public , Cryptosporidium , Parasites , CDC". www.cdc.gov. 2019-01-07. Retrieved 2019-11-12. " ... or surfaces contaminated with feces containing the Cryptosporidium. Immunocompromised people are the most susceptible. ...
Cryptosporidium is chlorine resistant. In order to minimize exposure to pathogens, swimmers should avoid getting water into ... "Cryptosporidium - Parasites". www.cdc.gov. Centers for Disease Control. Retrieved 2016-05-31. Centers for Disease Control and ... Arrowood Removal of Cryptosporidium and polystyrene microspheres from swimming pool water with sand, cartridge, and precoat ...
Membranes and bag and cartridge filters remove Cryptosporidium product-specifically.[citation needed] While Cryptosporidium is ... "Molecular epidemiology of Cryptosporidium spp. in calves in Estonia: high prevalence of Cryptosporidium parvum shedding and 10 ... "Update on Cryptosporidium spp.: highlights from the Seventh International Giardia and Cryptosporidium Conference". Parasite. 27 ... "Brote de diarrea y transmisión de Cryptosporidium hominis asociados al uso de pañal en niños" [Cryptosporidium hominis diarrhea ...
Parasites, particularly protozoa e.g., Cryptosporidium spp., Giardia spp., Entamoeba histolytica, Blastocystis spp., Cyclospora ...
Cryptosporidium sp. and Giardia sp. Infections in mountain gorillas (Gorilla gorilla beringei) of the Bwindi Impenetrable ... Cryptosporidium parvum genotype 2 infections in free-ranging mountain gorillas (Gorilla gorilla beringei) of the Bwindi ...
"Cryptosporidium strikes again". BBC News Online. 4 August 2002. Archived from the original on 19 January 2008. Retrieved 25 ... the waterborne parasite cryptosporidium was found in the Mugdock reservoir, and 140,000 people had to boil their water before ...
Cryptosporidium and Giardia are the two most prevalent parasites causing public health risk from water utilities in developed ... She filed a worldwide patent on her DNA method of diagnosing Cryptosporidium and was awarded a Frank Fenner Prize for Life ... "Project Number # 1068 Understanding and limiting the public health risks of Cryptosporidium and Giardia in animals in ... ISBN 978-1-78040-621-3. Ryan, Una (2014). Cryptosporidium Literature Review. London: IWA Publishing. ISBN 978-1-78040-620-6. " ...
Cryptosporidiosis (Cryptosporidium spp.) Cats transmit the protozoan through their feces. The symptoms in people weight loss ...
Cryptosporidium (the organism) and Cryptosporidiosis (the resulting disease) Toxoplasma (the organism) and Toxoplasmosis (the ... Some species of coccidia are transmissible to humans, including toxoplasma and cryptosporidium. Inside the host, the sporulated ... Genus Cryptosporidium. Amsterdam, The Netherlands: Universal Taxonomic Services. "Biodiversity explorer: Apicomplexa ( ...
Cryptosporidium can cause severe diarrhoea. About 140,000 people in Glasgow were affected, and were told not to drink tap water ... The water parasite cryptosporidium was discovered in Mugdock Reservoir at Milngavie Water Treatment Works on 4 August 2002, as ... "Cryptosporidium strikes again". BBC News Online. 4 August 2002. Retrieved 18 November 2007. (Use dmy dates from March 2018, Use ...
Brands, S.J. (2000). "The Taxonomicon & Systema Naturae". Taxon: Genus Cryptosporidium. Amsterdam, The Netherlands: Universal ... Diseases caused by Apicomplexa include: Babesiosis (Babesia) Malaria (Plasmodium) Cryptosporidiosis (Cryptosporidium parvum) ... and Cryptosporidium species (CryptoDB). One possible target for drugs is the plastid, and in fact existing drugs such as ... A Cryptosporidium bioinformatics resource update". Nucleic Acids Research. 34 (90001): D419-D422. doi:10.1093/nar/gkj078. PMC ...
Cryptosporidium can cause severe diarrhoea. About 140,000 people in Glasgow were affected - they were told not to drink tap ... 27 "Cryptosporidium strikes again". BBC News Online. 4 August 2002. Retrieved 18 November 2007. "Calls made for Milngavie's 9/ ... The new reservoir and treatment works were developed in the wake of the discovery of the waterborne cryptosporidium parasite in ...
The protozoans Cryptosporidium spp. and Giardia duodenalis and the nematode Trichinella spiralis have been reported. A 2021 ...
Retrieved 1 July 2021.{{cite web}}: CS1 maint: url-status (link) Melia, Paul (12 July 2016). "Cryptosporidium outbreak cost € ...
Cryptosporidium may survive in cold waters (4 °C) for up to 18 months, and can even withstand freezing, although its viability ... Cryptosporidium can be quite dangerous to patients with compromised immune systems. Alinia (nitazoxanide) is approved by the ... Studies of trips that are much longer than the average incubation period, e.g. a week for Cryptosporidium and Giardia, are less ... Because methods based on halogens, such as iodine and chlorine, do not kill Cryptosporidium, and because filtration misses some ...
Cryptosporidium parvum infection can be the cause of carcinoma in the gut of mice. Bouvard, V; Baan, R; Straif, K; Grosse, Y; ... Cryptosporidium parvum infection is associated with colorectal carcinoma. The roundworm Trichuris muris infection can increase ... Among protozoan parasites, Toxoplasma gondii, Cryptosporidium parvum, Trichomonas vaginalis and Theileria are associated with ... "Colorectal cancer and Cryptosporidium spp. infection". PLOS ONE. 13 (4): e0195834. Bibcode:2018PLoSO..1395834S. doi:10.1371/ ...
October 2004). "The genome of Cryptosporidium hominis". Nature. 431 (7012): 1107-12. Bibcode:2004Natur.431.1107X. doi:10.1038/ ... April 2004). "Complete genome sequence of the apicomplexan, Cryptosporidium parvum". Science. 304 (5669): 441-5. Bibcode: ...
October 2004). "The genome of Cryptosporidium hominis". Nature. 431 (7012): 1107-12. Bibcode:2004Natur.431.1107X. doi:10.1038/ ... April 2004). "Complete genome sequence of the apicomplexan, Cryptosporidium parvum". Science. 304 (5669): 441-5. Bibcode: ...
"The genome of Cryptosporidium hominis". Nature. 431 (7012): 1107-1112. Bibcode:2004Natur.431.1107X. doi:10.1038/nature02977. ...
Additionally, increased numbers of Cryptosporidium sp. and capillaria infections were found in gorillas that maintained more ... and Cryptosporidium parvum cannot be sapronotic agents. Categorizing of disease into epidemiologic classes by the infection's ...
Piper MB, Bankier AT, Dear PH (December 1998). "A HAPPY map of Cryptosporidium parvum". Genome Res. 8 (12): 1299-307. doi: ...
Fayer, R. (2004). "Cryptosporidium: a water-borne zoonotic parasite". Veterinary Parasitology. 126 (1-2): 37-56. doi:10.1016/j. ... An analysis in 2005 found Cryptosporidium parasites in stool samples from 100 mammals, including the scimitar oryx. Oocysts of ... a parasitic disease caused by protozoan parasites of the genus Cryptosporidium in the phylum Apicomplexa. A study in 2004 ... "Occurrence and molecular characterization of Cryptosporidium spp. in mammals and reptiles at the Lisbon Zoo". Parasitology ...
Cryptosporidium Infection, Cryptosporidiosis, fact sheets, information for special groups, prevention and control, epidemiology ... CDC at Work: Cryptosporidiumplus icon *CDC Works to Improve Cryptosporidium Tracking in the United States ... Cryptosporidium is a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Both the parasite and the ... There are many species of Cryptosporidium that infect animals, some of which also infect humans. The parasite is protected by ...
Cryptosporidium & Giardia Viability Testing Services. In addition to the detection of Cryptosporidium and Giardia in submitted ... Cryptosporidium Testing / Giardia Testing (USEPA Method 1623). Analytical Services, Inc. (ASI) has provided EPA Method 1623 ... Cryptosporidium infection can spread through multiple channels, including animal-to-human, person-to-person, and through water ... IVD - Cryptosporidium Stool Antigen Detection Microwell Elisa. to severe and even life-threatening complications. ...
PubMed Search: Cryptosporidium[TI] pathology free full text[sb] See Also: Colon nontumor, Lung nontumor, Small intestine ... Cryptosporidium spp. oocysts are red-pink using a modified acid fast stain (Pritt: Creepy Dreadful Wonderful Parasites Blog - ... Cryptosporidium spp. oocysts measure 4 - 6 micrometers in diameter (Pritt: Creepy Dreadful Wonderful Parasites Blog - Answer to ... Cite this page: Pernick N. Cryptosporidium. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ ...
Cryptosporidium enteritis is an infection of the small intestine that causes diarrhea. The parasite cryptosporidium causes this ... Cryptosporidium enteritis is an infection of the small intestine that causes diarrhea. The parasite cryptosporidium causes this ... Cryptosporidium has recently been recognized as a cause of diarrhea worldwide in all age groups. It has a greater effect on ... Certain water filters can also reduce risk by filtering out the cryptosporidium eggs. However, the pores of the filter must be ...
Cryptosporidium parvum is a major cause of moderate-to-severe diarrhea in humans and animals. Its compact genome contains 22 ... Cryptosporidium parvum is a major cause of moderate-to-severe diarrhea in humans and animals. Its compact genome contains 22 ... PCR amplification of the INS-21 gene (A) and INS-23 gene (B) of Cryptosporidium parvum. Lane M: 1000-bp molecular makers; Lane ... Figure 1. Sequence features of INS-21 and INS-23 of Cryptosporidium parvum. (A) Diagram of INS-21 (encoded by cgd7_2080) and ...
Detection of Cryptosporidium parvum antigen by co-agglutination test and ELISA  Michel, M.Y.; Khalifa, A.M.; Ibrahim, I.R. (‎ ... Confirmation of the presence of Cryptosporidium in environmental samples is laborious, costly and often difficult. We report ...
Unusual Cryptosporidium species recovered from human faeces: first description of Cryptosporidium felis and Cryptosporidium " ... Xiao L, Bern C, Limor J, Sulaiman I, Roberts J, Checkley W, Identification of 5 types of Cryptosporidium parasites in children ... Pieniazek NJ, Bornay-Llinares FJ, Slemenda SB, da Silva AJ, Moura IN, Arrowood MJ, New Cryptosporidium genotypes in HIV- ... Muthusamy D, Rao SS, Ramani S, Monica B, Banerjee I, Abraham OC, Multilocus genotyping of Cryptosporidium sp. isolates from ...
Mac Kenzie WR, Hoxie NJ, Proctor ME, Gradus MS, Blair KA, Peterson DE, A massive outbreak in Milwaukee of Cryptosporidium ... Mac Kenzie WR, Schell WL, Blair KA, Addiss DG, Peterson DE, Hoxie NJ, Massive outbreak of waterborne Cryptosporidium infection ... Cryptosporidium parvum, a protozoan parasite that causes gastrointestinal illness, is transmitted by ingestion of oocysts ... Costs of Illness in the 1993 Waterborne Cryptosporidium Outbreak, Milwaukee, Wisconsin On This Page ...
The risk of infection of Cryptosporidium via drinking water was assessed using Monte Carlo simulation with the field survey ... To calculate the annual risk of infection due to Cryptosporidium in drinking water, the Cryptosporidium level of Miyayama ... Assessment of risk of infection due to Cryptosporidium parvum in drinking water Y. Masago; Y. Masago ... Y. Masago, H. Katayama, A. Hashimoto, T. Hirata, S. Ohgaki; Assessment of risk of infection due to Cryptosporidium parvum in ...
Although Campylobacter, Listeria, Salmonella, Vibrio and Cryptosporidium are up, Shigella, E. coli O157:H7 and Yersinia are ... Home , Lawyer Op-Ed , Campylobacter, Listeria, Salmonella, Vibrio and Cryptosporidium are up, Shigella, E. coli O157:H7 and ... Campylobacter, Listeria, Salmonella, Vibrio and Cryptosporidium are up, Shigella, E. coli O157:H7 and Yersinia are down in new ...
Posts about Cryptosporidium parvum written by Phyllis Entis ... Tag: Cryptosporidium parvum. Recalls and Alerts: October 20-21 ... The Public Health Authority is investigating an outbreak of 61 confirmed cases of Cryptosporidium parvum since September 25, ...
Norby, S. M., Bharucha, A. E., Larson, M. V., & Temesgen, Z. (1998). Acute pancreatitis associated with Cryptosporidium parvum ... Acute pancreatitis associated with Cryptosporidium parvum enteritis in an immunocompetent man. S. M. Norby, A. E. Bharucha, M. ... Acute pancreatitis associated with Cryptosporidium parvum enteritis in an immunocompetent man. / Norby, S. M.; Bharucha, A. E. ... Norby, SM, Bharucha, AE, Larson, MV & Temesgen, Z 1998, Acute pancreatitis associated with Cryptosporidium parvum enteritis in ...
Prevalence and molecular characterization of Cryptosporidium spp. in dairy calves from 11 farms in Prince Edward Island, Canada ... Dive into the research topics of Prevalence and molecular characterization of Cryptosporidium spp. in dairy calves from 11 ...
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Read the paper: English, E.D., Guerin, A, Tandel, J. and Striepen, B. (2022) Live imaging of the Cryptosporidium parvum ... Read new paper in PLoS Biology that let us to suggest a significant revision of the lifecycle model for Cryptosporidium. Direct ...
The RIDA®QUICK Cryptosporidium is a quick immunochromatographic test for the qualitative determination of Cryptosporidium ... RIDA®QUICK Cryptosporidium (cassettes)2012-06-062018-07-06https://clinical.r-biopharm.com/wp-content/uploads/logo_rgb.png ...
... when chlorine stabilizer is in water Cite CITE. Title : Hyperchlorination to kill ... "Hyperchlorination to kill Cryptosporidium" (2012). National Center for Emerging and Zoonotic Infectious Diseases (U.S.). ... Recommendations to pool operators on how to hyperchlorinate to kill Cryptosporidium. Publication date from document properties ... Centers for Disease Control and Prevention (U.S.) "Hyperchlorination to kill Cryptosporidium when chlorine stabilizer is in ...
Cryptosporidium spp.) case definitions; uniform criteria used to define a disease for public health surveillance. ... Cryptosporidiosis (Cryptosporidium spp.) , 2012 Case Definition. *Cryptosporidiosis (Cryptosporidium spp.) , 2011 Case ... Cryptosporidiosis (Cryptosporidium spp.) , 2009 Case Definition. *Cryptosporidiosis (Cryptosporidium spp.) , 1998 Case ...
Effect of Microbial Metabolites on Growth of Cryptosporidium Sibley, L. David Washington University, Saint Louis, MO, United ... For example, high fecal indole levels were associated with lower susceptibility in a human challenge study of Cryptosporidium. ... Our studies explore the use of naturally occurring bacterial metabolites to inhibit growth of the parasite Cryptosporidium, a ... One method by which the microbiota may influence susceptibility to Cryptosporidium infection is through the production of ...
Cryptosporidium and Giardia are chlorine-resistant protozoan that can be inactivated with UV light. ... Cryptosporidium & Giardia Barrier. Municipalities around the world install TrojanUV systems to inactivate Cryptosporidium and ... About Cryptosporidium. *Cryptosporidium is a protozoa that causes a diarrheal illness called cryptosporidiosis ... UV Treatment as a Cryptosporidium Barrier. Cryptosporidium is resistant to chlorine, but has been shown to be effectively ...
Prevalence of Cryptosporidium infection in cows and artificial infection of Cryptosporidium parvum in neonatal calves. Chinese ... Cryptosporidium infection in livestock and first identification of Cryptosporidium parvum genotype in cattle feces in Taiwan. ... Genetic characterization of Cryptosporidium spp. in Hotan Black Chickens in China reveals two novel subtypes of Cryptosporidium ... Biology, persistence and detection of Cryptosporidium parvum and Cryptosporidium hominis oocyst. Water Research, 38(4), 818-862 ...
Cryptosporidium infection impairs growth and muscular protein synthesis in suckling rats. Parasitology Research, 2005, 96 (5), ...
Continue Reading 50 sick in Cryptosporidium outbreak linked to farm UK Shigella outbreak linked to spring onions from Egypt. By ... 50 sick in Cryptosporidium outbreak linked to farm. By News Desk on May 24, 2023. ... Fifty cases of Cryptosporidium have been traced to a farm on an island off the south coast of England. ...
Cryptosporidium​. (Binominal: Cryptospordium parvum). Cryptosporidium is a protozoal parasite that causes the diarrheal disease ... Similar to Cryptosporidium, it is resistant to disinfectants due to having an outer shell allowing it to survive outside the ...
... to evaluate the humoral immune response induced against peptides derived from Cryptosporidium parvum CP15 (15 kDa sporozoite ... Cryptosporidium spp. is a zoonotic intracellular protozoan and a significant cause of diarrhoea in humans and animals worldwide ... Cryptosporidium parvum ,. Dna ,. Peptides ,. Protozoan proteins ,. Protozoan vaccines ,. Cp15 ,. Cryptosporidiosis ,. ... Cryptosporidium parvum ,. Drug formulation ,. Drug synthesis ,. Enzyme linked immunosorbent assay ,. Female ,. Humoral immunity ...
The protozoa Cryptosporidium and Giardia are major causes of diarrhea and are commonly found on vegetables in China. They pose ... Health risks of Cryptosporidium and Giardia in the application of surface water and septic tank effluent in Chinese agriculture ... Criptosporidiose Cryptosporidium Giardíase Neoplasias Humanos Giardíase/epidemiologia Giardia Criptosporidiose/epidemiologia ... A quantitative microbial risk assessment of Chinese data evaluated the risks of Cryptosporidium and Giardia exposure arising ...
Anti-Cryptosporidium Antibody , MCRPT-55A-1A9 , Immunology Consultatnt Laboratory Host: Mouse Format: Unconjugated AP Product ...
Cryptosporidium Genitourinary infections, especially those due to Chlamydia trachomatis, are the second most common cause of ...
Cryptosporidium is a protozoan parasite causing gastrointestinal illness. Drinking waterborne outbreaks have been caused by C. ... PDF (Novel real time PCR assays for the specific detection of human infective Cryptosporidium species) - Published Version ... Novel real-time PCR assays for the specific detection of human infective Cryptosporidium species ... Molecular detection techniques already exist for Cryptosporidium and usually target housekeeping genes. We set ourselves the ...
  • Cryptosporidium is a microscopic parasite that causes the diarrheal disease cryptosporidiosis. (cdc.gov)
  • Cryptosporidiosis (Cryptosporidium species). (medlineplus.gov)
  • Cryptosporidiosis (Cryptosporidium spp. (cdc.gov)
  • Cryptosporidiosis caused by Cryptosporidium parvum subtype IIdA15G1 at a dairy farm in Northwestern China. (parasite-journal.org)
  • Joan Shields] Well, the germs Cryptosporidium and Giardia cause most recreational water associated outbreaks. (cdc.gov)
  • Dan Rutz] Tell me, what is Cryptosporidium and Giardia ? (cdc.gov)
  • Joan Shields] Cryptosporidium and Giardia are parasites that infect the intestinal tract. (cdc.gov)
  • Results were also positive for Cryptosporidium for samples tested by using an immunochromatographic (Crypto-Strip, Coris Bioconcept, Gembloux, Belgium) ( 4 ) and an immunofluorescent assay (Merifluor Cryptosporidium / Giardia , Meridian Diagnostics, Cincinnati, OH, USA). (cdc.gov)
  • The Zai Water Treatment Plant, which takes raw water from the canal, was required by the Ministry to install UV to treat Cryptosporidium and Giardia . (trojantechnologies.com)
  • Epidemiological Investigation and Molecular Characteristics of Giardia and Cryptosporidium in Zhongmou County, Henan. (parasite-journal.org)
  • Assessment of zoonotic transmission of Giardia and Cryptosporidium between cattle and humans in rural villages in Bangladesh. (parasite-journal.org)
  • Several Cryptosporidium species and Giardia duodenalis assemblages, some of which are of potential zoonotic relevance, as well as Entamoeba spp. (bvsalud.org)
  • Nitazoxanide inhibits the growth of Cryptosporidium parvum and Giardia lamblia trophozoites. (medscape.com)
  • The prevalence was 16% for Giardia lamblia , 13% for Entamoeba histolytica / E . d ispar , 8% for Cryptosporidium spp, 5% for Isospora belli , 1.5% for Blastocystis hominis, 2.5% for Ascaris lumbricoides and 2% for Hymnolepis nana . (who.int)
  • Cryptosporidium oocysts were detected by direct microscopic visualization of the samples, which had been concentrated by formalin-ethyl acetate sedimentation and stained with a modified Ziehl-Neelsen stain. (cdc.gov)
  • Cryptosporidium parvum , a protozoan parasite that causes gastrointestinal illness, is transmitted by ingestion of oocysts excreted in human or animal feces. (cdc.gov)
  • In 1993, an estimated 403,000 residents of the greater Milwaukee, Wisconsin, area (population, approximately 1.61 million) became ill when an ineffective filtration process led to the inadequate removal of Cryptosporidium oocysts in one of two municipal water treatment plants ( 6 ). (cdc.gov)
  • Bromine and chlorine disinfection of Cryptosporidium parvum oocysts, Bacillus atrophaeus spores, and MS2 coliphage in water. (cdc.gov)
  • However, protozoan pathogens such as oocysts of Cryptosporidium parvum are very resistant to chlorine , which has led to consideration of alternative disinfectants for their control. (cdc.gov)
  • The objectives of this study are to (1) compare the efficacy of free bromine to free chlorine at similar concentrations (as milligrams per liter) for disinfection of Cryptosporidium parvum oocysts, Bacillus atrophaeus spores, and MS2 coliphage in a model buffered water and (2) evaluate the kinetics of inactivation of these microorganisms using appropriate disinfection models. (cdc.gov)
  • Prevalence and molecular characterization of Cryptosporidium spp. (bris.ac.uk)
  • Dive into the research topics of 'Prevalence and molecular characterization of Cryptosporidium spp. (bris.ac.uk)
  • The result obtained showed prevalence of 19.8% and 22.8%, for Cryptosporidium parvum, using both microscopy and Enzyme Linked Immunosorbent Assay. (ijsrp.org)
  • 2008. High prevalence of Cryptosporidium bovis and the deer-like genotype in calves compared to mature cows in beef cow-calf operations. (parasite-journal.org)
  • Prevalence and genotyping of Cryptosporidium in three cattle husbandry systems in Zambia. (parasite-journal.org)
  • Prevalence of Cryptosporidium infection in cows and artificial infection of Cryptosporidium parvum in neonatal calves. (parasite-journal.org)
  • To estimate the prevalence of contamination with Cryptosporidium spp. (bvsalud.org)
  • Molecular methods identified Cryptosporidium ryanae, Cryptosporidium bovis, Cryptosporidium xiaoi, and Cryptosporidium ubiquitum in both matrices, with a prevalence of 5.1% (95% C.I. 3.3-7.3). (bvsalud.org)
  • A distinct seasonality in prevalence was observed for G. duodenalis, with most positives occurring in spring, whereas Cryptosporidium showed no significant seasonal variations . (bvsalud.org)
  • To provide an estimate of exposure to this organism, the prevalence of antibodies to cryptosporidium will be measured in NHANES participants aged 6-49 years. (cdc.gov)
  • Objective: To systematically review prevalence of Cryptosporidium species among HIV/AIDS patients in Sub Saharan Africa. (peertechzpublications.com)
  • 200 cells/µL) and the prevalence of Cryptosporidium spp, Isospora belli , and Blastocystis hominis . (who.int)
  • Cryptosporidium enteritis is an infection of the small intestine that causes diarrhea. (medlineplus.gov)
  • The parasite cryptosporidium causes this infection. (medlineplus.gov)
  • Coccidian protozoans that belong to the genus Cryptosporidium frequently cause gastrointestinal infection in humans and animals and are distributed worldwide. (cdc.gov)
  • The risk of infection of Cryptosporidium via drinking water was assessed using Monte Carlo simulation with the field survey data of the Sagami River watershed. (iwaponline.com)
  • To calculate the annual risk of infection due to Cryptosporidium in drinking water, the Cryptosporidium level of Miyayama sampling point was used as the water source of the waterworks. (iwaponline.com)
  • Additionally, neonatal animals, which harbor an immature microbiota, are much more susceptible to Cryptosporidium infection than adults. (grantome.com)
  • One method by which the microbiota may influence susceptibility to Cryptosporidium infection is through the production of inhibitory small molecule metabolites. (grantome.com)
  • Collectively, these findings raise the intriguing hypothesis that metabolites produced by the microbiota influence susceptibility to infection with Cryptosporidium. (grantome.com)
  • Investigation on cow infection with Cryptosporidium parvum in south areas of Guangxi. (parasite-journal.org)
  • [ 57 , 59 ] In clinical trials, nitazoxanide significantly reduced the duration of diarrhea, increased the rate of parasitological eradication, and improved the mortality rate in malnourished children with Cryptosporidium infection who were HIV seronegative. (medscape.com)
  • ABSTRACT We investigated the rate of infection by Cryptosporidium parvum among children from birth to 12 years attending Princess Rahma Teaching Hospital in Irbid, Jordan and evaluated various diagnostic meth- ods. (who.int)
  • addition, we tried to focus on some epide- miological factors that lead to infection in Cryptosporidium parvum is a coccidian children. (who.int)
  • Free bromine, HOBr, has not been evaluated extensively as an alternative halogen disinfectant for inactivation of Cryptosporidium parvum in drinking water or reclaimed water for non-potable uses. (cdc.gov)
  • There are many species of Cryptosporidium that infect animals, some of which also infect humans. (cdc.gov)
  • However, other species and genotypes of Cryptosporidium , such as C. felis , C. muris , C. meleagridis , C. canis , C. parvum pig genotype, and C. parvum cervine genotype, have also been detected in stool samples of immunosuppressed and immunocompetent patients ( 1 ). (cdc.gov)
  • The transmission route for the unusual Cryptosporidium species is unclear. (cdc.gov)
  • The identification of Cryptosporidium species (Protozoa) in Ifsahan, Iran by PCR-RFLP analysis of the 18S rRNA gene. (parasite-journal.org)
  • Background: Cryptosporidium species is increasingly recognized as a leading cause of diarrheal disease with life threatening condition in HIV/AIDS patients. (peertechzpublications.com)
  • Cryptosporidium species is one of the AIDS defining illnesses and associated with an increased risk of death compared to other AIDS-defining illnesses. (peertechzpublications.com)
  • The Public Health Authority is investigating an outbreak of 61 confirmed cases of Cryptosporidium parvum since September 25, 2022. (efoodalert.com)
  • In 1993, more than 100 people died and over 400,000 developed gastrointestinal illnesses as a result of a Cryptosporidium outbreak in the drinking water supply of Milwaukee, Wisconsin . (trojantechnologies.com)
  • After the Milwaukee outbreak, many water treatment plants installed UV in order to meet the USEPA Long Term 2 Enhanced Surface Water Treatment Rule , since Cryptosporidium treatment was required. (trojantechnologies.com)
  • surfaces that kills pathogens like bacteria (E. coli, Staphylococcus, Legionella, etc.), viruses (MS2) and protozoa ( Cryptosporidium ) from water, with no power, no chemicals and no maintenance. (environmental-expert.com)
  • 1999. Identification of Cryptosporidium felis in a cow by morphologic and molecular methods. (parasite-journal.org)
  • Molecular characterization of Cryptosporidium parvum from two different Japanese prefectures, Okinawa and Hokkaido. (parasite-journal.org)
  • Molecular characterization of Cryptosporidium from animal sources in Qinghai province of China. (parasite-journal.org)
  • Molecular detection techniques already exist for Cryptosporidium and usually target housekeeping genes. (uea.ac.uk)
  • Intestinal parasitic infections are among intestinal opportunistic agents, such as Cryptosporidium the most common infections world-wide. (who.int)
  • Género de parásitos coccidioides de la familia CRYPTOSPORIDIAE que se encuentran en el epitelio intestinal de muchos vertebrados, incluyendo el hombre. (bvsalud.org)
  • Identification and characterization of a Chinese isolate of Cryptosporidium serpentis from dairy cattle. (parasite-journal.org)
  • The sequence of the PCR product was determined, and a comparison with all SSU rDNA Cryptosporidium sequences available in databanks showed 100% similarity with the homologous fragment of C. felis (GenBank accession no. (cdc.gov)
  • Cryptosporidium hominis and the cattle genotype of C. parvum are responsible for most human infections. (cdc.gov)
  • 2004. Biology, persistence and detection of Cryptosporidium parvum and Cryptosporidium hominis oocyst. (parasite-journal.org)
  • As an enteric pathogen, Cryptosporidium interacts with the complex microbial community that constitutes the microbiome. (grantome.com)
  • There are several treatments for cryptosporidium enteritis. (medlineplus.gov)
  • Using this type of treatment can lead to a complete remission of cryptosporidium enteritis. (medlineplus.gov)
  • Joan Shields] Well, like I said, Cryptosporidium has become the leading cause of pool- associated outbreaks of diarrheal disease and these outbreaks are on the increase. (cdc.gov)
  • Cryptosporidium is an important cause of outbreaks of waterborne disease in the United States. (cdc.gov)
  • During 2000-2014, the majority of outbreaks linked to pools, hot tubs, or water playgrounds were caused by the parasite Cryptosporidium . (cdc.gov)
  • The occurrence of Cryptosporidium parvum , Campylobacter and Salmonella in newborn dairy calves in the Manawatu region of New Zealand. (parasite-journal.org)
  • For detection of Cryptosporidium spp , lsospora belli and Cyclospora spp, the modified Zeihl-Neelsen staining method was used. (who.int)
  • For example, a swimmer infected with the parasite Cryptosporidium can release 10-100 million germs into the water. (cdc.gov)
  • Swallowing 10 or fewer Cryptosporidium germs can make you sick. (cdc.gov)
  • Research has shown that swim diapers might hold in some solid feces but these diapers only delay diarrhea-causing germs, like Cryptosporidium , from leaking into the water by a few minutes. (cdc.gov)
  • Although Campylobacter , Listeria , Salmonella , Vibrio and Cryptosporidium are up, Shigella , E. coli O157:H7 and Yersinia are down that does not seem to justify a late Friday night posting on the CDC's website. (marlerblog.com)
  • If the daily risk was eliminated when the level of Cryptosporidium in treated water exceeded 1 oocyst per 20L, the 95% percentile of the annual risk was reduced by about 1 log. (iwaponline.com)
  • To reduce the 95% value of the annual risk lower than 10 −4 , the risk of days with levels of Cryptosporidium in treated water exceeding 1 oocyst per 80L should be eliminated. (iwaponline.com)
  • In the United States, Cryptosporidium is the leading cause of swimming pool-associated diarrheal illness. (cdc.gov)
  • Cryptosporidium is a leading cause of waterborne disease among humans in the United States. (cdc.gov)
  • The RIDA®QUICK Cryptosporidium is a quick immunochromatographic test for the qualitative determination of Cryptosporidium parvum in stool samples. (r-biopharm.com)
  • Cryptosporidium is a protozoan parasite causing gastrointestinal illness. (uea.ac.uk)
  • Cryptosporidium is resistant to chlorine, but has been shown to be effectively inactivated with UV treatment. (trojantechnologies.com)
  • After washing, the pellets were examined by microscopy (FLOTAC) and tested using conventional simplex PCR , targeting Cryptosporidium spp. (bvsalud.org)
  • Certain water filters can also reduce risk by filtering out the cryptosporidium eggs. (medlineplus.gov)
  • The Long Term Enhanced Surface Water Treatment Rule requires unfiltered surface water plants to install treatment to inactivate Cryptosporidium . (trojantechnologies.com)
  • It also stimulated efforts to develop regulatory standards for Cryptosporidium in drinking water. (cdc.gov)
  • However, Cryptosporidium has a tough outer shell and can survive for more than 7 days in properly treated water. (cdc.gov)
  • Cryptosporidium has recently been recognized as a cause of diarrhea worldwide in all age groups. (medlineplus.gov)
  • Cryptosporidium parvum is a major cause of moderate-to-severe diarrhea in humans and animals. (frontiersin.org)
  • Similar to Cryptosporidium, it is resistant to disinfectants due to having an outer shell allowing it to survive outside the body for long periods of time. (guineapigcages.com)
  • Relative to other treatment technologies, such as ozone and membrane filtration, UV offers a cost-effective solution for Cryptosporidium inactivation. (trojantechnologies.com)
  • For example, high fecal indole levels were associated with lower susceptibility in a human challenge study of Cryptosporidium. (grantome.com)
  • Cryptosporidium parvum has been recognized as a human pathogen since 1976. (cdc.gov)
  • M16 metalloproteases are also common in apicomplexans, but Cryptosporidium spp. (frontiersin.org)
  • Confirmation of the presence of Cryptosporidium in environmental samples is laborious, costly and often difficult. (who.int)

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