A family of parasitic organisms in the order EIMERIIDA. CRYPTOSPORIDIUM is the most important genus.
A subclass of protozoans commonly parasitic in the epithelial cells of the intestinal tract but also found in the liver and other organs. Its organisms are found in both vertebrates and higher invertebrates and comprise two orders: EIMERIIDA and EUCOCCIDIIDA.
A genus of coccidian parasites of the family CRYPTOSPORIDIIDAE, found in the intestinal epithelium of many vertebrates including humans.

Kinetic characterization of bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from Cryptosporidium hominis: a paradigm shift for ts activity and channeling behavior. (1/3)

This study presents a kinetic characterization of the recently crystallized bifunctional thymidylate synthasedihydrofolate reductase (TS-DHFR) enzyme from the apicomplexa parasite, Cryptosporidium hominis. Our study focuses on determination of the C. hominis TS-DHFR kinetic mechanism, substrate channeling behavior, and domain-domain communication. Unexpectedly, the unique mechanistic features of C. hominis TS-DHFR involve the highly conserved TS domain. At 45 s(-) (1), C. hominis TS activity is 10-40-fold faster than other TS enzymes studied and a new kinetic mechanism was required to simulate C. hominis TS behavior. A large accumulation of dihydrofolate produced at TS and a lag in product formation at DHFR were observed. These observations make C. hominis TS-DHFR the first bifunctional TS-DHFR enzyme studied for which there is clear evidence against dihydrofolate substrate channeling. Furthermore, whereas with Leishmania major TS-DHFR there are multiple lines of evidence for domain-domain communication (ligand binding at one active site affecting activity of the other enzyme), no such effects were observed with C. hominis TS-DHFR.  (+info)

Issue a boil-water advisory or wait for definitive information? A decision analysis. (2/3)

OBJECTIVE: Study the decision to issue a boil-water advisory in response to a spike in sales of diarrhea remedies or wait 72 hours for the results of definitive testing of water and people. METHODS: Decision analysis. RESULTS: In the base-case analysis, the optimal decision is test-and-wait. If the cost of issuing a boil-water advisory is less than 13.92 cents per person per day, the optimal decision is to issue the boil-water advisory immediately. CONCLUSIONS: Decisions based on surveillance data that are suggestive but not conclusive about the existence of a disease outbreak can be modeled.  (+info)

Back to basics: a revealing secondary reduction of the mitochondrial protein import pathway in diverse intracellular parasites. (3/3)

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Cryptosporidiidae is a family of Apicomplexa, which are single-celled, parasitic organisms that infect a wide range of animals, including humans. Members of this family are known to cause cryptosporidiosis, a diarrheal disease in humans and other animals.

The most well-known genus within Cryptosporidiidae is Cryptosporidium, which includes several species that can infect humans. These parasites have a complex life cycle that involves both sexual and asexual reproduction, and they are transmitted through the fecal-oral route, often through contaminated water or food.

Cryptosporidiosis is typically a self-limiting disease in healthy individuals, but it can be severe or even life-threatening in people with weakened immune systems, such as those with HIV/AIDS or receiving immunosuppressive therapy after organ transplantation. There are currently no effective drugs to treat cryptosporidiosis, although research is ongoing to develop new therapies.

Coccidia are a group of single-celled, microscopic parasites that belong to the phylum Apicomplexa. They are obligate intracellular parasites, which means they need to infect and live inside the cells of a host organism to survive and multiply. Coccidia are primarily found in animals, including mammals, birds, reptiles, and fish, but some species can also infect humans.

Coccidia are known to cause coccidiosis, a common intestinal disease that affects various animal species, including poultry, cattle, swine, sheep, goats, and pets such as cats and dogs. The disease is characterized by diarrhea, weight loss, dehydration, and sometimes death, particularly in young animals.

In humans, coccidia infection is usually caused by the species Cryptosporidium and Cyclospora. These parasites can infect the small intestine and cause watery diarrhea, stomach cramps, nausea, vomiting, fever, and weight loss. In immunocompromised individuals, such as those with HIV/AIDS or those undergoing chemotherapy, coccidia infections can be severe and life-threatening.

Coccidia are typically transmitted through the fecal-oral route, either by ingesting contaminated food or water or by direct contact with infected animals or their feces. Prevention measures include good hygiene practices, such as washing hands thoroughly after handling animals or using the restroom, avoiding drinking untreated water from sources that may be contaminated with animal feces, and practicing safe food handling and preparation.

Cryptosporidium is a genus of protozoan parasites that can cause the diarrheal disease known as cryptosporidiosis in humans and animals. These microscopic pathogens infect the epithelial cells of the gastrointestinal tract, primarily in the small intestine, leading to symptoms such as watery diarrhea, stomach cramps, nausea, vomiting, fever, and dehydration.

Cryptosporidium parasites have a complex life cycle, including several developmental stages within host cells. They are protected by an outer shell called oocyst, which allows them to survive outside the host's body for extended periods, making them resistant to chlorine-based disinfectants commonly used in water treatment.

Transmission of Cryptosporidium occurs through the fecal-oral route, often via contaminated water or food, or direct contact with infected individuals or animals. People at higher risk for severe illness include young children, elderly people, pregnant women, and those with weakened immune systems due to HIV/AIDS, cancer treatment, or organ transplantation.

Preventive measures include proper hand hygiene, avoiding consumption of untreated water or raw fruits and vegetables likely to be contaminated, and practicing safe sex. For immunocompromised individuals, antiparasitic medications such as nitazoxanide may help reduce the severity and duration of symptoms.

Apicomplexa: Cryptosporidiidae) from the Red Kangaroo (Macropus rufus)". Journal of Eukaryotic Microbiology. 55 (1): 22-26. doi ...
The first of them - Gregarinomorphea - comprises Orthogregarinia, Cryptosporidiidae and, additionally, Rhytidocystidae ...
... cryptosporidiidae MeSH B01.500.841.075.189.250.150.160 - cryptosporidium MeSH B01.500.841.075.189.250.150.160.170 - ...
Apicomplexa: Cryptosporidiidae) from the Red Kangaroo (Macropus rufus)". Journal of Eukaryotic Microbiology. 55 (1): 22-26. doi ...
Categories: Cryptosporidiidae Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 9 ...
Cryptosporidiosis is caused by protozoan parasites of the genus Cryptosporidium (family Cryptosporidiidae, order Eucoccidiorida ...
Re-description of Cryptosporidium cuniculus Inman and Takeuchi 1979 (Apicomplexa:Cryptosporidiidae): morphology, biology and ...
n. (Apicomplexa: Cryptosporidiidae) in Psittaciformes birds. Nikola Holubová, Veronika Zikmundová, Zlata Limpouchová, et al.. ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOPHILIN A. CICLOFILINA A. CICLOFILINA A. CYCLOPHILINS. ...
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CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOPHILIN A. CICLOFILINA A. CICLOFILINA A. CYCLOPHILINS. ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOPHILIN A. CICLOFILINA A. CICLOFILINA A. CYCLOPHILINS. ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOPHILIN A. CICLOFILINA A. CICLOFILINA A. CYCLOPHILINS. ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOSPORA. CYCLOSPORA. CYCLOSPORA. DEFENSINAS. DEFENSINS. DEFENSINAS ...
CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CRYPTOSPORIDIIDAE. CYCLOPHILIN A. CICLOFILINA A. CICLOFILINA A. CYCLOPHILINS. ...
Cryptosporidiidae. Genus: Cryptosporidium. Species Cryptosporidium andersoni. Cryptosporidium bailey. Cryptosporidium canis. ...
Cryptosporidiidae. family. Decreases. Source Study Enterobacteriaceae. family. Decreases. Source Study Enterobacteriaceae. ...
cyclosporiasis. Medical Information Search
Disease due to Cryptosporidiidae. *Gastritis caused by Cryptosporidium. *Infection by Cryptosporidium. *Infection by ...
Cryptosporidiidae) in multiple Spermophilus ground Squirrel species." International Journal for Parasitology-Parasites and ...
Cryptosporidiidae), which causes diarrhea in humans, often leading to outbreaks [103]. Cryptosporidium parvum global prevalence ...
Cryptosporidiidae) are described globally. Members of this genus occur within a broad spectrum of hosts - vertebrates, ...
n., Cryptosporidium ducismarci Traversa, 2010 and Cryptosporidium tortoise genotype III (Apicomplexa: Cryptosporidiidae) in ...
  • Cryptosporidiosis is caused by protozoan parasites of the genus Cryptosporidium (family Cryptosporidiidae, order Eucoccidiorida, subclass. (cabi.org)
  • Currently, 41 valid species and several dozen genotypes of parasites included in the Cryptosporidium (Apicomplexa: Cryptosporidiidae) are described globally. (svupraha.cz)

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