Cryptorchidism
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
Hypospadias
Orchiopexy
Testis
Testicular Hydrocele
Genitalia, Male
Urogenital Surgical Procedures
Heptachlor Epoxide
Leydig Cells
Chlordan
Seminiferous Tubules
Infertility, Male
Urogenital Abnormalities
Organotin Compounds
Testicular Neoplasms
Spermatogenesis
Testosterone
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Endocrine Disruptors
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
Sertoli Cells
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
Gonadal Dysgenesis
A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual abnormalities is reflected in their varied sex chromosome (SEX CHROMOSOMES) constitution as shown by the karyotypes of 45,X monosomy (TURNER SYNDROME); 46,XX (GONADAL DYSGENESIS, 46XX); 46,XY (GONADAL DYSGENESIS, 46,XY); and sex chromosome MOSAICISM; (GONADAL DYSGENESIS, MIXED). Their phenotypes range from female, through ambiguous, to male. This concept includes gonadal agenesis.
Prenatal Exposure Delayed Effects
Maternal Exposure
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
Hypogonadism
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
Kallmann Syndrome
A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.
Puberty, Delayed
The lack of development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations above the mean age at onset of PUBERTY in a population. Delayed puberty can be classified by defects in the hypothalamic LHRH pulse generator, the PITUITARY GLAND, or the GONADS. These patients will undergo spontaneous but delayed puberty whereas patients with SEXUAL INFANTILISM will not.
Osteoporosis
Gonadotropins
Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.
DAX-1 Orphan Nuclear Receptor
An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
International trends in rates of hypospadias and cryptorchidism. (1/499)
Researchers from seven European nations and the United States have published reports of increasing rates of hypospadias during the 1960s, 1970s, and 1980s. Reports of increasing rates of cryptorchidism have come primarily from England. In recent years, these reports have become one focus of the debate over endocrine disruption. This study examines more recent data from a larger number of countries participating in the International Clearinghouse for Birth Defects Monitoring Systems (ICBDMS) to address the questions of whether such increases are worldwide and continuing and whether there are geographic patterns to any observed increases. The ICBDMS headquarters and individual systems provided the data. Systems were categorized into five groups based on gross domestic product in 1984. Hypospadias increases were most marked in two American systems and in Scandinavia and Japan. The increases leveled off in many systems after 1985. Increases were not seen in less affluent nations. Cryptorchidism rates were available for 10 systems. Clear increases in this anomaly were seen in two U.S. systems and in the South American system, but not elsewhere. Since 1985, rates declined in most systems. Numerous artifacts may contribute to or cause upward trends in hypospadias. Possible "real" causes include demographic changes and endocrine disruption, among others. (+info)Management of the impalpable testis: the role of laparoscopy. (2/499)
PURPOSE: To evaluate the use of laparoscopy in the management of the impalpable testis. DESIGN: A retrospective analysis of the clinical findings, interventions, and outcome in 87 consecutive boys undergoing laparoscopy for 97 impalpable testes. RESULTS: Fifty seven testes were either absent (n = 35) or present as a small remnant (n = 22), which was removed at contemporaneous groin exploration. There were 27 intra-abdominal testes, including four hypoplastic testes, which were removed laparoscopically. The 13 remaining viable testes were located in the groin. Conventional orchidopexy followed laparoscopy for 21 testes, and was successful in 17 cases. Two stage laparoscopically assisted Fowler Stevens orchidopexies were performed for 13 intra-abdominal testes, with eight satisfactory results. Ultrasound evaluation significantly reduced the number of conventional orchidopexies following laparoscopy. IMPLICATIONS: Laparoscopy is a rational and safe approach for precise localisation of the impalpable testis. Laparoscopically assisted two stage orchidopexy is a successful treatment procedure for intra-abdominal testes. (+info)Experimental cryptorchidism induces a change in the pattern of expression of LH receptor mRNA in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate. (3/499)
In the rat, the cytotoxic drug ethylene dimethane sulfonate (EDS) selectively eliminates mature Leydig cells (LCs) from testicular interstitium, activating a complex process of proliferation and differentiation of pre-existing LC precursors. We observed previously that after EDS treatment, the early LC precursors persistently express a truncated 1.8 kb form of LH receptor (LHR) mRNA. This prompted us to study whether experimental cryptorchidism, known to alter the process of LC repopulation, can influence the pattern of testicular LHR mRNA expression after EDS administration. EDS treatment completely eliminated mature LCs both in control and unilaterally cryptorchid (UC) rats. This response was followed by gradual reappearance of newly formed, functionally active LCs, as evidenced by the recovery in testicular LHR content and plasma testosterone levels in both experimental groups. Noteworthy, the rate of LC repopulation was higher in the abdominal testes of UC rats, in keeping with previous findings. Interestingly, the 1.8 kb LHR transcript was persistently expressed in scrotal testes at all time-points, but undetectable upon Northern hybridization in abdominal testes at early stages after EDS administration, when low levels of expression of truncated LHR transcripts could only be detected by semi-quantitative RT-PCR analysis. In addition, the faster LC repopulation in cryptorchid testes was associated with precocious recovery of the complete array of LHR mRNA transcripts, including the 1.8 kb species. These changes appeared acutely and irreversibly, as unilateral positioning of scrotal testes into the abdomen resulted in a rapid loss of expression of the 1.8 kb LHR transcript, whereas scrotal relocation of the UC testes failed to alter the pattern of LHR gene expression. In conclusion, experimental cryptorchidism changes the pattern of LHR mRNA expression in rat testis after selective LC destruction by EDS. This change, i.e. repression of the 1.8 kb LHR transcript after EDS administration, is acute and irreversible, and likely related to the impairment of testicular microenvironment following cryptorchidism. However, even though at low levels, the expression of truncated forms of LHR mRNA appears to be a universal feature of proliferating LC precursors. The UC testis may represent a good model for analysis of the regulatory signals involved in the control of LHR gene expression. (+info)Ooplasmic injections of rabbit round spermatid nuclei or intact round spermatids from fresh, cryopreserved and cryostored samples. (4/499)
We compared the outcome of ooplasmic round spermatid nuclear injections (ROSNI) versus intact round spermatid injections (ROSI). Rabbit round spermatid nuclei and intact round spermatids were recovered and injected into rabbit oocytes (groups A and B, respectively). Fertilization, cleavage and embryonic development rates were compared. In additional studies, five protocols for cryopreservation of round spermatids and two protocols for cryostorage of round spermatids were applied. The outcome of ROSNI techniques using frozen-thawed or cryostored-warmed round spermatids was evaluated. The cleavage rate and the overall morula plus blastocyst development rate were significantly larger in group A than group B. ROSNI procedures are superior to ROSI techniques in the rabbit. The largest fertilization, cleavage and embryonic development rates after ROSNI techniques using cryopreserved or cryostored round spermatids were demonstrated in groups of round spermatids in which a mixture of seminal plasma plus test yolk buffer was employed as an extender, and dimethyl sulphoxide plus a high concentration of glycerol served as cryoprotectants. It appears that the seminal plasma contains factors protecting round spermatids during cryopreservation or cryostorage, and/or the employment of two cryoprotectants has a beneficial role in the maintenance of round spermatid reproductive capacity. (+info)Risk factors for testicular cancer: a case-control study in twins. (5/499)
Early life and anthropometric risk factors for testicular cancer were examined in a case-control study in England and Wales in which affected male twins were compared with their unaffected male co-twins. Questionnaire data was obtained for 60 twin pairs. Significantly raised risk of testicular cancer occurred in twins who had longer arms and legs than their co-twin. There was a significant excess of testicular cancer reported in non-twin brothers, as well as in twin brothers, of cases. Risk was also significantly raised in relation to cryptorchidism. The results on limb length suggest that factors, perhaps nutritional, affecting growth before puberty, may be causes of testicular cancer. The results on risk in brothers add to evidence of a large genetic component in aetiology of the tumour. The risk associated with cryptorchidism in the twins accords with the hypothesis that cryptorchidism is causally associated with testicular cancer because it is a cause of the malignancy, rather than because the same maternal factors experienced in utero cause both conditions. (+info)Improvement of spermatogenesis in adult cryptorchid rat testis by intratesticular infusion of lactate. (6/499)
In order to test the hypothesis that a lack of energy could be a cause of germ cell death at high temperatures, cryptorchid rats testes were infused with lactate, delivered by osmotic pumps over 3-15 days. In cryptorchid testes, the spermatids and spermatocytes were lost between 3 and 8 days. In cryptorchid testes supplemented with lactate, elongated spermatids persisted in a few seminiferous tubules at Day 15. Elimination of round spermatids occurred progressively between 3 and 15 days, mostly at stage VIII. The loss of spermatocytes increased after 8 days, and 30% of seminiferous tubules still contained meiotic or meiotic plus spermiogenetic cells at Day 15. After 8 days, the chromatin of step 8 round spermatids was abnormal and nuclear elongation did not commence. The Sertoli cell cytoplasm that was retracted toward the basal compartment of the seminiferous epithelium could not hold the germ cells of the adluminal compartment. Therefore, attachment of germ cells to Sertoli cells and the supply of lactate seem necessary for the development of germ cells at high temperatures. The improvement in spermatogenesis in cryptorchid supplemented testes for several days is a new finding. (+info)Incidence of testicular cancer in the United States: has the epidemic begun to abate? (7/499)
In response to a report that testicular cancer incidence in non-Hispanic White males in Los Angeles county had fallen in the 1990s, particularly in young men, the authors analyzed data collected by the Surveillance, Epidemiology, and End Results (SEER) program from 1973 to 1995. While the incidence rate of testicular cancer in US White males ages 15-64 years did stabilize in the first half of the 1990s, after a number of years of a steady increase, there was no indication of an actual decline. (+info)Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H, and cryptorchid mice. (8/499)
The nature of the spermatogenic arrest in cryptorchid C57Bl mice and in jsd/jsd and Sl17H/Sl17H mutant mice was identified by studying whole mounts of seminiferous tubules. In all three types of mice, virtually only A spermatogonia were found, topographically arranged in clones of 1 to 16 (rarely more) cells. These clonal sizes are typical for undifferentiated spermatogonia. The proportion of these cells lying in chains of more than 2 cells (50-70%) was comparable to that seen in epithelial stages VII-VIII in the normal epithelium. It is concluded that in all three types of mice, spermatogenesis is arrested at the point where the undifferentiated A spermatogonia, specifically A(al) spermatogonia, differentiate into the first generation of the differentiating-type spermatogonia, the A1 spermatogonia. The remaining A spermatogonia were proliferating, but no accumulation of spermatogonia was present, as spermatogonial apoptosis also took place. Spermatogonial clones of all sizes were seen to undergo apoptosis, but there were relatively many large apoptotic clones, indicating that the clones became more vulnerable when they became larger. In contrast to what is seen in the normal epithelium, odd-numbered clones, not composed of 2(n) cells, were present, as well as clumps of 2 or more spermatogonial nuclei in the same cytoplasm, in all three types of mice. This indicates a lack of integrity of spermatogonial clones, also observed in other situations with a relative paucity of cells on the basal membrane. It is concluded that the differentiation of the undifferentiated spermatogonia, affected in all three types of mice as well as in vitamin A-deficient animals, is a rather vulnerable point in the spermatogenic developmental pathway. (+info)Impaired Sertoli cell function in experimental cryptorchidism in the rat | Meta
SPAG5 mRNA is over-expressed in peripheral blood leukocytes of patients with Downs syndrome and cryptorchidism. | IRIS...
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Difference between revisions of 2014 Group Project 9 - Embryology
Cryptorchidism
... may develop after infancy, sometimes as late as young adulthood, but that is exceptional. Cryptorchidism is ... In horses, cryptorchidism is sufficiently common that affected males (ridglings) are routinely gelded. Rarely, cryptorchidism ... Wikimedia Commons has media related to Cryptorchidism. Kidshealth.org: Cryptorchidism (CS1 maint: location, CS1 maint: DOI ... Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is ...
Cryptorchidism-arachnodactyly-intellectual disability syndrome
... is a rare multi-systemic genetic disorder of unknown prevalence ... "Cryptorchidism-arachnodactyly-intellectual disability syndrome (Concept Id: C4707233) - MedGen - NCBI". www.ncbi.nlm.nih.gov. ... "Orphanet: Cryptorchidism arachnodactyly intellectual disability syndrome". www.orpha.net. Retrieved 2022-05-30. "Van Benthem- ... cryptorchidism, hypospadias, and testicular agenesis. No new cases have been reported since 1970. RESERVED, INSERM US14-- ALL ...
Cremasteric reflex
ISBN 978-0-443-06612-2. "Cryptorchidism". The Lecturio Medical Concept Library. Retrieved 20 July 2021. Mellick LB, Mowery ML, ... this reflex may be exaggerated which can occasionally lead to a misdiagnosis of cryptorchidism. The cremasteric reflex may be ...
List of OMIM disorder codes
FGFR2 Cryptorchidism, bilateral; 219050; LGR8 Cryptorchidism, idiopathic; 219050; INSL3 Currarino syndrome; 176450; MNX1 Cutis ...
Pomeranian dog
Another common disorder in male Pomeranians is cryptorchidism. This is when either one or both of the testicles do not descend ... Ward, Ernest (2009). "Cryptorchidism in Dogs". Shores Animal Clinic. Lifelearn. Retrieved 21 January 2011. "Pomeranian Care: ...
Gonocyte
Individuals diagnosed with cryptorchidism are often at risk of testicular cancer and infertility due to dysfunction in the ... Cryptorchidism, also known as undescended testis, is a common birth defect affecting male genital formation. ... Loebenstein, Moshe; Thorup, Jorgen; Cortes, Dina; Clasen-Linde, Erik; Hutson, John M; Li, Ruili (2019). "Cryptorchidism, ... Leslie, Stephen W.; Sajjad, Hussain; Villanueva, Carlos A. (2020), "Cryptorchidism", StatPearls, StatPearls Publishing, PMID ...
Ridgling
"Cryptorchidism in the horse". equine-reproduction.com. Retrieved 2015-08-12. McDonnell, Sue (3 April 2013). "Castrated and ... "Cryptorchidism (Undescended Testicles) in Horses ACVS". www.acvs.org. Retrieved 2015-08-12. Paulick, Ray (5 November 2004). " ... When a male horse thought to be a gelding exhibits aggressive or sexual behavior, cryptorchidism is suspected. Sometimes, a ... but cryptorchidism also can be an issue in dogs and cats. Because the heat inside the body is too high for sperm to survive, an ...
Ectopic testis
Cryptorchidism Orchiopexy Stevenson, Roger; Hall, Judith (2006). Human malformations and related anomalies. Oxford New York: ...
Testicle
This is called cryptorchidism. In most cases of cryptorchidism, the issue will mostly resolve itself within the first half year ... Cryptorchidism, or "undescended testicles", is when the testicle does not descend into the scrotum of an infant boy. Testicular ... Microscopic view of Rabbit testis 100× Testicle Anorchia Bollocks Cryptorchidism (cryptorchismus) Ejaculation Eunuchs Gelding ...
Testicular dysgenesis syndrome
In Cryptorchidism a diagnosis is made from a physical examination which is performed when the baby is lacking one or both ... The risk factors for Cryptorchidism are: A family history of the condition Low birth weight Prematurity Poor semen quality is ... Risk factors for TC include: Cryptorchidism Family history Previous testicular cancer The diagnosis is confirmed in different ... The downstream disorders of such abnormalities can include both genital malformations (e.g. hypospadias and cryptorchidism) and ...
USP9Y
Dada R, Gupta NP, Kucheria K (2003). "Cryptorchidism and AZF microdeletion". Asian J. Androl. 4 (2): 148. PMID 12085107. Dada R ... Gupta NP, Kucheria K (2003). "AZF microdeletions associated with idiopathic and non-idiopathic cases with cryptorchidism and ...
Richard M. Ehrlich
"Hormonal therapy of cryptorchidism." New England Journal of Medicine 314.8 (1986): 466-470. Ehrlich, R. M. et al. "Laparoscopic ...
Kallmann syndrome
Cryptorchidism (undescended testicles) at birth. Low levels of the gonadotropins LH and FSH. Hypogonadism due to low levels of ... cryptorchidism) in males. Measuring testicular volume. Checking for breast development and age at menarche in females. Checking ...
Birth defects of diethylstilbestrol
Additional research published in Finland in 2012 has further confirmed an increased risk of cryptorchidism among males exposed ... Virtanen HE, Adamsson A (May 2012). "Cryptorchidism and endocrine disrupting chemicals". Molecular and Cellular Endocrinology. ... such as cryptorchidism and hypospadias. Research published in the U.S. by Palmer et al. in 2009 further confirmed evidence of ... "Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities". The ...
Tetrasomy 18p
In males, cryptorchidism is common. Abnormal genitalia in females is not a common feature. Renal abnormalities have been ...
INSL3
The mutations in this gene may lead to, but not a frequent cause of, cryptorchidism. GRCh38: Ensembl release 89: ... Nef S, Parada LF (July 1999). "Cryptorchidism in mice mutant for Insl3". Nature Genetics. 22 (3): 295-9. doi:10.1038/10364. ... no relationship with cryptorchidism". Pediatric Research. 47 (4 Pt 1): 538-41. doi:10.1203/00006450-200004000-00020. PMID ... "Insulin-like 3/relaxin-like factor gene mutations are associated with cryptorchidism". The Journal of Clinical Endocrinology ...
X-linked ichthyosis
Cryptorchidism is reported in some individuals. Individuals with XLI appear at increased risk of developmental disorders such ...
Glycerol kinase deficiency
Cryptorchidism, the failure of one or both of the testes to descend to the scrotum, has been known to lead to sexual identity ... Galifer, R. B.; Kalfa, N.; Guibal, M. P. (2004). "What a hidden testicle can hide?...or the clinical traps of cryptorchidism". ... Symptoms visible at or shortly after birth include: cryptorchidism strabismus seizures Some other symptoms that become more ... such as cryptorchidism, strabismus, learning disabilities, and myopathy, tend to have an added psychological effect on the ...
Gonadorelin
... cryptorchidism, and infertility. Unlike other GnRH analogues, it is not used to suppress sex hormone production. Gonadorelin is ...
Sun Ra
By his teens, Blount suffered from cryptorchidism. It left him with a nearly constant discomfort that sometimes flared into ...
Splenogonadal fusion
These cases were found in patients who also had a history of cryptorchidism, which is a known risk factor for testicular cancer ... The reported cases have occurred in patients with a history of cryptorchidism, which is associated with an elevated risk of ... The most commonly associated malformation is cryptorchidism. When limb abnormalities occur, Splenogonadal Fusion with Limb ... and most commonly cryptorchidism. Terminal limb defects have been documented in at least 25 cases which makes up a separate ...
XYY syndrome
These include cryptorchidism, hypoplastic scrotum, microphallus, and hypospadias. These men could be diagnosed with infertility ...
Monorchism
Anorchia Cryptorchidism Polyorchidism Allen, Arthur (29 July 1999). "Triumph of the cure". Salon. "Milestones: Jan. 23, 1984". ... also known as undescended testis or cryptorchidism. In this case the testis is within the abdominal cavity, somewhere along the ...
Orchiopexy
Cryptorchidism is associated with tubular atrophy and sterility. In addition, cryptorchid testes carry a three to five times ... The first attempts at surgical correction of cryptorchidism began in the early 1800s. Before this, inguinal testis were managed ... Cryptorchidism is definitively diagnosed after 1 year of age, as testicular descent may occur after birth. Surgical placement ... Early orchiopexy reduces the risks for cancer and sterility in males with cryptorchidism, or undescended testes.[citation ...
Paul J. Turek
Cryptorchidism: prepubertal orchidopexy may prevent testis cancer J Urol. 178:1440-6; discussion 1446, 2007 , Walsh TJ, Davies ...
Okamoto syndrome
... cryptorchidism). A small minority of those affected have had congenital joint contractures such as club foot. Those with ...
Spigelian hernia
Some common complications of this distinct syndrome cryptorchidism are testicular torsion, and its link to testicular cancer. ... Raveenthiran V (Dec 2005). "Congenital Spigelian hernia with cryptorchidism: probably a new syndrome". Hernia. 9 (4): 378-80. ... Raveenthiran described a new syndrome in which Spigelian hernia and cryptorchidism (undescended testis) occur together. ... Obstructed indirect Component and Direct Component with Cryptorchidism". Case Reports in Surgery. 2011: 1461425. doi:10.1155/ ...
Anogenital distance
Hypospadias and cryptorchidism are conditions which may be induced in males with short AGD. Other problems in males include ... Hsieh MH, Breyer BN, Eisenberg ML, Baskin LS (March 2008). "Associations among hypospadias, cryptorchidism, anogenital distance ... disruption of which leads to hypospadias and cryptorchidism". Journal of Clinical Investigation. 118 (4): 1479-1490. doi: ...
Akhal-Teke
Cryptorchidism is said to be related to health and behavior problems. Affected horses are more expensive to castrate. There are ... Hereditary cryptorchidism exists within the Akhal-Teke breed and affected stallions can be traced through multiple generations ... Some national Akhal Teke associations, however, ban Cryptorchidism from breeding. The Akhal-Teke is one of many light riding ... Breeders balance the risk of cryptorchidism against propagating other desirable qualities. ...
Kerry Blue Terrier
Hip dysplasia, hypothyroidism, and cryptorchidism have also been reported occasionally. Progressive neuronal abiotrophy (PNA) ...
Cryptorchidism Treatment & Management: Approach Considerations, Medical Therapy, Surgical Therapy
Cryptorchidism literally means hidden or obscure testis and generally refers to an undescended or maldescended testis. ... Cryptorchidism is the most common genital problem encountered in pediatrics. ... encoded search term (Cryptorchidism) and Cryptorchidism What to Read Next on Medscape ... in boys with cryptorchidism and polymorphisms in patients with cryptorchidism and in the general population. [6] Analysis of ...
Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism
... for cryptorchidism. Exposure to ibuprofen and acetylsalicylic acid was not associated with cryptorchidism. ... Cryptorchidism was identified in 980 boys during childhood, of whom 565 underwent orchiopexy. The use of acetaminophen, ... Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism Epidemiology. ... We estimated adjusted hazard ratios (HRs) of cryptorchidism by Cox regression analysis. ...
Cryptorchidism (Retained Testicles) in Dogs and Cats - Veterinary Partner - VIN
Cryptorchidism: a registry based study in Sweden on some factors of possible aetiological importance. | Journal of Epidemiology...
International trends in rates of hypospadias and cryptorchidism.
Proteomic profiles of unilateral cryptorchidism in pigs at different ages using MALDI-TOF mass spectrometry and in-gel...
The present study revealed the specific PMFs and clusters for porcine cryptorchidism, and a novel protein, TNFRSF18, associated ... Cryptorchidism is a condition that occurs when one or both testes fail to descend into the scrotum. It is a common congenital ... Cryptorchidism is a condition that occurs when one or both testes fail to descend into the scrotum. It is a common congenital ... Cryptorchidism is a condition that occurs when one or both testes fail to descend into the scrotum, which can reduce fertility ...
Cryptorchidism Guidelines: Guidelines Summary
Cryptorchidism literally means hidden or obscure testis and generally refers to an undescended or maldescended testis. ... Cryptorchidism is the most common genital problem encountered in pediatrics. ... encoded search term (Cryptorchidism) and Cryptorchidism What to Read Next on Medscape ... Cryptorchidism Guidelines. Updated: Oct 10, 2022 * Author: Joel M Sumfest, MD; Chief Editor: Edward David Kim, MD, FACS more... ...
Cryptorchidism Workup: Laboratory Studies, Imaging Studies
Cryptorchidism literally means hidden or obscure testis and generally refers to an undescended or maldescended testis. ... Cryptorchidism is the most common genital problem encountered in pediatrics. ... encoded search term (Cryptorchidism) and Cryptorchidism What to Read Next on Medscape ... Cryptorchidism in boys with congenital abdominal wall defects. Pediatr Surg Int. 1998 Mar. 13(2-3):143-5. [QxMD MEDLINE Link]. ...
KosmikCattery - Cryptorchidism
What is Cryptorchidism?. Cryptorchidism is when the testicles do not descend properly into the scrotum, one or two may or may ... Cryptorchidism can be unilateral (only occurring on one side) or bilateral (occurring on both sides). Unilateral cryptorchidism ... Depending on the breed, instances of cryptorchidism may be as high as 30%. Breeds commonly affected include Persians and ... The neutering process on cats with cryptorchidism is slightly more complicated than a regular castration. Two separate ...
Causes of Cryptorchidism? | ProHomeworkMarket
Which of the following is a cause of cryptorchidism?. A. Infertility. B. Testicular cancer. C. High serum testosterone. D. Prostatitis. E. Short spermatic cord. 4. Which of the following substances may start to appear in the urine when the glomerulus is inflamed?. A. Sodium. B. Potassium. C. Glucose. D. Protein. E. Urea. 5. Which of the following is a major cause of hepatocellular carcinoma?. A. Peritonitis. B. Autoimmunity. C. Hemorrhage. D. Liver cirrhosis. E. Anorexia. ...
Hormones for Cryptorchidism | Zheln
Hypogonadism: Practice Essentials, Background, Pathophysiology
cryptorchidism Archives - Small Animal Ultrasonography
Undescended Testes (Cryptorchidism) | Boston Children's Hospital
Undescended Testes (Cryptorchidism) , Frequently Asked Questions. Do undescended testicles cause pain? No, there is no pain ... Undescended Testes (Cryptorchidism) , Symptoms & Causes. What are the symptoms of an undescended testicle?. In a baby affected ... Undescended Testes (Cryptorchidism) , Diagnosis & Treatments. How are undescended testicles diagnosed?. A primary care doctor ... Undescended Testes (Cryptorchidism) , Programs & Services. Departments. Urology. Department The clinicians in the Department of ...
IMSEAR at SEARO: Leydig cell tumour in a case of bilateral cryptorchidism.
The inconspicuous penis in children | Nature Reviews Urology
Undescended testicle: MedlinePlus Medical Encyclopedia
Pediatric Rubella Follow-up: Further Outpatient Care, Further Inpatient Care, Deterrence/Prevention
Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours | Nature Reviews Urology
Congenital Bilateral Spigelian-Cryptorchidism Syndrome? A Case Report
| APSP Journal of Case Reports
PDF) Comparison of Conventional and Laparoscopic Abdominal Cryptorchidectomy in Dogs (2008-2017)
Results: cryptorchidism was more common in pure breeds and it affected mainly the right testicle. The operating time to remove ... Laparoscopy versus parapreputial laparotomy for the treatment of abdominal cryptorchidism in dogs. July 2013 · CES VETERINARY ... in dogs suffering from unilateral abdominal cryptorchidism. Materials and methods: 11 patients were used. The average weight of ...
Swiss Medical Weekly - Collection 2008/3334
Wilms' tumor: Symptoms, treatment, and causes
Educational-Resources - Urology Care Foundation
15 month old yorkie vomited undigested food several times. | Ask A Vet
Reproductive Disorders of Male Cats - Cat Owners - MSD Veterinary Manual
NIOSHTIC-2 Search Results - Full View
The hypothalamus-pituitary-testis axis in boys during the first six months of life: a comparison of cryptorchidism and ... Moreover, it is unclear whether these hormone levels are aberrant in boys with cryptorchidism or hypospadias, and therefore ... Secondly, we studied testicular function - as reflected by HPT hormones - in newborns with cryptorchidism or hypospadias. Sera ... with a mean testosterone of 1.8 and 2.6 nmol/L and a mean NSBT of 0.48 and 0.70 nmol/L for cryptorchidism cases and controls, ...
HypospadiasTestesBilateralTesticleUnilateral cryptorchidismOccurrence of cryptorchidismCongenitalTesticles do not descendSyndromeScrotumDescendInguinalDiagnosisDysgenesisFairly commonTesticular descentOrchiopexyInfertilityTestisCancerMalesGuidelinesSurgicalPatientsChildhoodCasesTreatmentCommonlyCatsSearchBoysStudyAnimalMonthsReduce
Hypospadias8
- International trends in rates of hypospadias and cryptorchidism. (cdc.gov)
- Assess the possibility of a DSD in cases of increasing severity of hypospadias with cryptorchidism. (medscape.com)
- The hypothalamus-pituitary-testis axis in boys during the first six months of life: a comparison of cryptorchidism and hypospadias cases with controls. (cdc.gov)
- Moreover, it is unclear whether these hormone levels are aberrant in boys with cryptorchidism or hypospadias, and therefore predictive for future fertility. (cdc.gov)
- Secondly, we studied testicular function - as reflected by HPT hormones - in newborns with cryptorchidism or hypospadias. (cdc.gov)
- Sera from a population sample of infants with cryptorchidism (n = 43), hypospadias (n = 41) and controls (n = 113) were analyzed for inhibin B, anti-Mullerian hormone (AMH), testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH) and sex hormone binding globulin (SHBG). (cdc.gov)
- Concerns about the increasing incidence of abnormalities in human and animal male reproductive function, such as cryptorchidism, hypospadias, low sperm count and testicular germ cell cancer, have been steadily increasing [1] , [2] . (plos.org)
- Specifically, the higher occurrence of cryptorchidism and hypospadias might be the result of increasing alterations of the function of fetal Leydig cells. (plos.org)
Testes5
- Cryptorchidism is a condition that occurs when one or both testes fail to descend into the scrotum. (biomedcentral.com)
- Cryptorchidism is a condition that occurs when one or both testes fail to descend into the scrotum, which can reduce fertility and increase the risk of testicular malignancies [ 1 ]. (biomedcentral.com)
- Undescended testicles, also known as cryptorchidism, is a fairly common and normally painless congenital condition in which one or both of a baby's testicles (testes) have not moved into the proper position. (childrenshospital.org)
- Testes that didn't descend the way they should (cryptorchidism). (webmd.com)
- Undescended Testes and Retractile Testes Undescended testes (cryptorchidism) are testes that remain in the abdomen or the groin instead of descending into the scrotum. (msdmanuals.com)
Bilateral4
- Cryptorchidism can be unilateral (only occurring on one side) or bilateral (occurring on both sides). (kosmikcattery.com)
- IMSEAR at SEARO: Leydig cell tumour in a case of bilateral cryptorchidism. (who.int)
- Congenital Bilateral Spigelian-Cryptorchidism Syndrome? (apspjcaserep.com)
- We present a 24-year-old man with a history of bilateral cryptorchidism, complaining of lower abdominal mass for two months. (bvsalud.org)
Testicle1
- Unilateral cryptorchidism usually involves the right testicle. (kosmikcattery.com)
Unilateral cryptorchidism1
- Unilateral Cryptorchidism. (pinoyexchange.com)
Occurrence of cryptorchidism2
- We examined whether prenatal exposure to acetaminophen, ibuprofen, and acetylsalicylic acid was associated with increased occurrence of cryptorchidism. (nih.gov)
- Maternal intake of acetaminophen for more than 4 weeks during pregnancy, especially during the first and second trimesters, may moderately increase the occurrence of cryptorchidism. (nih.gov)
Congenital2
- Prevalence of congenital cryptorchidism in Estonia. (medscape.com)
- Cryptorchidism is the most common congenital malformation of the male genitourinary tract. (bvsalud.org)
Testicles do not descend1
- Cryptorchidism is when the testicles do not descend properly into the scrotum, one or two may or may not properly descend. (kosmikcattery.com)
Syndrome1
- The biopsy reported cryptorchidism of insensitivity syndrome. (bvsalud.org)
Scrotum1
- Cryptorchidism is a failure of one or both testicles to descend into the scrotum. (msdvetmanual.com)
Descend1
- Cryptorchidism, a condition where one or both of the testicles fail to descend before birth, is one of the most common male genital birth defects, affecting approximately 2 to 8 percent of full-term male infants, and around 33 percent of premature infants. (asu.edu)
Inguinal2
- CONCLUSION: In patients with cryptorchidism on one side and an inguinal hernia on the other side, the surgeon must consider a rare condition known as transverse testicular ectopia. (bvsalud.org)
- se detectó presencia de gónadas en canal inguinal y paravesical. (bvsalud.org)
Diagnosis1
- Late diagnosis of cryptorchidism: a failure of medical screening? (bmj.com)
Dysgenesis1
- Males often have cryptorchidism while females have a bifid uterus and renal dysgenesis has been reported. (arizona.edu)
Fairly common1
- Cryptorchidism is fairly common in premature births and occurs in full term births at a much lesser rate. (justmommies.com)
Testicular descent3
- Exposure for more than 4 weeks within the postulated time-window of programming testicular descent (gestational weeks 8-14) was associated with a HR of 1.38 (1.05-1.83) for cryptorchidism. (nih.gov)
- Refer infants with a history of cryptorchidism (detected at birth) who do not have spontaneous testicular descent by 6 months (corrected for gestational age) to an appropriate surgical specialist for timely evaluation. (medscape.com)
- Zhang K, Zhang Y, Chao M. Effect of adjunctive hormonal therapy on testicular descent and spermatogenic function among children with cryptorchidism: a systematic review and meta-analysis. (zheln.com)
Orchiopexy2
Infertility1
- The AUA advises that providers should counsel boys with a history of cryptorchidism and/or monorchidism, and their parents, regarding potential long-term risks and provide education on infertility and cancer risk. (medscape.com)
Testis1
- Cryptorchidism can be subclassified by the location of the maldescended testis. (bvsalud.org)
Cancer2
- Correcting cryptorchidism decreases the risk of testicular cancer. (msdmanuals.com)
- However, even if cryptorchidism is corrected, the risk of cancer is still higher than for men who never had cryptorchidism. (msdmanuals.com)
Males1
- Our findings support the early treatment and close monitoring of cases of cryptorchidism due to the risk of malignancy as well as the necessity of routine scrotal examinations in all males presenting with an abdominal mass. (bvsalud.org)
Guidelines1
- American Urolological Association guidelines recommend against imaging studies in boys with cryptorchidism prior to surgical referral. (medscape.com)
Surgical1
- Refer boys with possible newly diagnosed (acquired) cryptorchidism after 6 months (corrected for gestational age) to an appropriate surgical specialist. (medscape.com)
Patients1
- Mutational analysis of HOXA10 gene in Chinese patients with cryptorchidism. (medscape.com)
Childhood1
- Cryptorchidism is best corrected surgically in childhood. (msdmanuals.com)
Cases3
- The only significant group-differences were lower testosterone and NSBT levels in cryptorchidism cases, with a mean testosterone of 1.8 and 2.6 nmol/L and a mean NSBT of 0.48 and 0.70 nmol/L for cryptorchidism cases and controls, respectively. (cdc.gov)
- Cryptorchidism has also been reported in several cases. (orpha.net)
- The results of this survey can also be helpful in the cases of cryptorchidism. (webdesignfinders.net)
Treatment3
- A meta-analysis of hCG treatment of cryptorchidism concluded that hCG treatment is no more effective than placebo. (medscape.com)
- GnRH is available as a nasal spray but is approved for the treatment of cryptorchidism only in Europe. (medscape.com)
- Evaluation and treatment of cryptorchidism: AUA guideline. (medscape.com)
Commonly1
- Although most of these disorders (other than cryptorchidism) are rare, the most commonly encountered conditions are discussed below. (msdvetmanual.com)
Cats1
- The neutering process on cats with cryptorchidism is slightly more complicated than a regular castration. (kosmikcattery.com)
Search1
- La resonancia conception, RACC1: manuscript magnética describe presencia de estructura de aspecto tubular bilobulada compuesta por dos imágenes nodulares, las design, literature search, data collection, data or software cuales se ubican adyacentes a la pared vesical en su aspecto posterior, lateral y superior derecho de 27,4 × 15,4 × 11,0 mm. management. (bvsalud.org)
Boys2
- Obtain gestational history at initial evaluation of boys with suspected cryptorchidism. (medscape.com)
- Do not perform ultrasound (US) or other imaging modalities in the evaluation of boys with cryptorchidism prior to referral, as these studies rarely assist in decision making. (medscape.com)
Study2
- Cryptorchidism: a registry based study in Sweden on some factors of possible aetiological importance. (bmj.com)
- The present study revealed the specific PMFs and clusters for porcine cryptorchidism, and a novel protein, TNFRSF18, associated with the disease mechanism. (biomedcentral.com)
Animal1
- Although animal breeders intensively select sire lines with no cryptorchidism in the great-grandparent (GGP) or grandparent (GP) generations, cryptorchidism often appears in the fattening pigs. (biomedcentral.com)
Months1
- Cryptorchidism should be treated when the patient is approximately 6 months old. (medscape.com)
Reduce1
- The expression of protein markers could possibly be utilized not only for unveiling the aberrant mechanism underlying the disease, but also for selection of suitable sires from the GGPs and GPs, which might reduce the incidence of cryptorchidism in fattening pigs. (biomedcentral.com)