Macroporous hydrogels that are produced at subzero temperatures. Cryogels have pores that are produced by growing ice crystals and have been developed with a tissue-like elasticity that is suitable for cell immunization experiments.
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.
Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.
Schools which offer training in the area of health.
Terms or expressions which provide the major means of access by subject to the bibliographic unit.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
The physiological renewal, repair, or replacement of tissue.
The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Application of principles and practices of engineering science to biomedical research and health care.
The research and development of ELECTRICAL EQUIPMENT AND SUPPLIES for such medical applications as diagnosis, therapy, research, anesthesia control, cardiac control, and surgery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The teaching staff and members of the administrative staff having academic rank in a medical school.
Electrical devices that are composed of semiconductor material, with at least three connections to an external electronic circuit. They are used to amplify electrical signals, detect signals, or as switches.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.
A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
The misinterpretation of a real external, sensory experience.
A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed)
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.
Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)

Detachment of affinity-captured bioparticles by elastic deformation of a macroporous hydrogel. (1/9)

Adsorption of bioparticles to affinity surfaces involves polyvalent interactions, complicating greatly the recovery of the adsorbed material. A unique system for the efficient binding and release of different cells and particles is described. Affinity-bound bioparticles and synthetic particles are detached from the macroporous hydrogel matrix, a so-called cryogel, when the cryogel undergoes elastic deformation. The particle detachment upon elastic deformation is believed to be due to breaking of many of the multipoint attachments between the particles and the affinity matrix and the change in the distance between affinity ligands when the matrix is deformed. However, no release of affinity-bound protein occurred upon elastic deformation. The phenomenon of particle detachment upon elastic deformation is believed to be of a generic nature, because it was demonstrated for a variety of bioparticles of different sizes and for synthetic particles, for different ligand-receptor pairs (IgG-protein A, sugar-ConA, metal ion-chelating ligand), and when the deformation was caused by either external forces (mechanical deformation) or internal forces (the shrinkage of thermosensitive, macroporous hydrogel upon an increase in temperature). The elasticity of cryogel monoliths ensures high recovery of captured cells under mild conditions, with highly retained viability. This property, along with their continuous porous structure makes cryogel monoliths very attractive for applications in affinity cell separation.  (+info)

Supermacroprous chitosan-agarose-gelatin cryogels: in vitro characterization and in vivo assessment for cartilage tissue engineering. (2/9)

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Apparent heterogeneity in the pIII-peptide fusion protein in single-phage clones isolated from peptide libraries. (3/9)

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Injectable preformed scaffolds with shape-memory properties. (4/9)

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Effect of scaffold microarchitecture on osteogenic differentiation of human mesenchymal stem cells. (5/9)

Design of macroporous synthetic grafts that can promote infiltration of cells, their differentiation, and synthesis of bone-specific extracellular matrix is a key determinant for in vivo bone tissue regeneration and repair. In this study, we investigated the effect of the microarchitecture of the scaffold on osteogenic differentiation of human mesenchymal stem cells (hMSCs). Poly(ethylene glycol) diacrylate-co-N-acryloyl 6-aminocaproic acid cryogels were fabricated to have either a pore network consisting of cellular, randomly oriented pores (termed 'spongy') or a pore network consisting of lamellar columns (termed 'columnar'), with both cryogel types showing a similar porosity. Both spongy and columnar cryogels supported comparable levels of cell viability and proliferation of hMSCs in vitro. However, spongy cryogels promoted osteogenic differentiation to a greater extent than their columnar counterparts, as evidenced by increased alkaline phosphatase activity and osteoblastic gene expression over 21 days post culture. Leveraging upon our previous work, we further evaluated the ability of these synthetic scaffolds in conjunction with mineralisation to promote ectopic bone formation upon subcutaneous implantation in nude rats. Mineralised spongy and columnar cryogels, both in the presence and absence of exogenous hMSCs, promoted ectopic bone formation in vivo. No such bone formation was observed in acellular cryogels devoid of mineralisation, with extensive host cell infiltration and vascularisation in columnar cryogels, and negligible infiltration into spongy cryogels. Our results thus present a novel method to tune the microarchitecture of porous polymeric scaffolds, in addition to suggesting their efficacy as synthetic bone grafts.  (+info)

Designing polysaccharide-based antibacterial biomaterials for wound healing applications. (6/9)

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Effect of alpha-ketoglutarate on growth and metabolism of cells cultured on three-dimensional cryogel matrix. (7/9)

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Three-dimensional supermacroporous carrageenan-gelatin cryogel matrix for tissue engineering applications. (8/9)

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A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic Principles of Cryotropic Gelation Vladimir I. Lozinsky, Oguz Okay Synthesis, Structure-Property Relationships of Cryogels Oguz Okay, Vla
TY - JOUR. T1 - Polymeric Cryogel‐Based Boronate Affinity Chromatography for Separation of Ribonucleic Acid from Bacterial Extracts. AU - Shakya, Akhilesh. AU - Srivastava, Akshay. AU - Kumar, Ashok. PY - 2015/12/1. Y1 - 2015/12/1. N2 - Three-dimensional monolithic columns are preferred stationary phase in column chromatography. Conventional columns based on silica or particles are efficient in bioseparation though associated with limitations of nonspecific interaction and uneven porosity that causes high mass transfer resistance for the movement of big molecules. Cryogels as a monolith column have shown promising application in bioseparation. Cryogels column can be synthesized in the form of a monolith at sub-zero temperature through gelation of pre-synthesized polymers or polymerization of monomers. Cryogels are macroporous and mechanically stable materials. They have open interconnected micron-sized pores with a wide range of porosity (10-200 μm). Current protocol demonstrated the ability ...
Here, we report for the first time the use of p(AAc (p(acrylic acid)) cryogel for in situ metal nanoparticle preparation, and their use as a superporous reactor for H-2 generation from hydrolysis of NaBH4. Superporous p(AAc) cryogels and conventional hydrogels were prepared via free radical polymerization technique at low (-18 degrees C) and moderate (40 degrees C) temperatures, respectively. They were characterized by employing various methods such as swelling experiments, optical imaging, and SEM (Scanning Electron Microscopy) analysis. By reducing Co2+ and Ni2+ ions within p(AAc) cryogel and hydrogel matrices, the obtained Co and Ni metal nanoparticles were employed for H-2 generation from NaBH4 hydrolysis. Various factors such as porosity, metal type, temperature, and the amount of sodium hydroxide were investigated to determine their effects on hydrogen generation from NaBH4 hydrolysis. Activation energy (Ea), enthalpy (Delta Eta(#)) and entropy (Delta S-#) for NaBH4 hydrolysis by ...
TY - JOUR. T1 - A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation. AU - Razavi, Mehdi. AU - Primavera, Rosita. AU - Kevadiya, Bhavesh D.. AU - Wang, Jing. AU - Buchwald, Peter. AU - Thakor, Avnesh S.. PY - 2020/4/1. Y1 - 2020/4/1. N2 - The aim of this article is to develop, characterize, and test a novel 3D bioscaffold matrix that can accommodate pancreatic islets and provide them with a continuous, controlled, and steady source of oxygen to prevent hypoxia-induced damage following transplantation. Hence, a collagen-based cryogel bioscaffold that incorporates calcium peroxide (CPO) into its matrix is made. The optimal concentration of CPO integrated into bioscaffolds is 0.25 wt% and this generates oxygen at 0.21 ± 0.02 × 10-3 m day-1 (day 1), 0.19 ± 0.01 × 10-3 m day-1 (day 6), 0.13 ± 0.03 × 10-3 m d-1 (day 14), and 0.14 ± 0.02 × 10-3 m d-1 (day 21). Accordingly, islets seeded into cryogel-CPO bioscaffolds have a significantly higher viability and ...
The influence of temperature, pH and ionic strength on the adsorption of Immunoglobulin Y (IgY) in IDA-Cu(2+) cryogel system was studied by batch equilibrium measurements.
Poly(HEMA) cryogel disks were synthesized by free radical polymerization of 2-hydroxy-ethylmethacrylate (HEMA), and then Cibacron Blue F3GA (CB), Reactive Green 19 (RG) and Congo Red (CR) were immobilized as dye ligands. Disks were...
Feng, Y., Xue, Y., Guo, J., Cheng, L., Jiao, L., Zhang, Y. and Yue, J. (2009), Synthesis and characterization of poly(carbonate urethane) networks with shape-memory properties. J. Appl. Polym. Sci., 112: 473-478. doi: 10.1002/app.29426 ...
Pre-Shaped Injectable Jelly for Drug Delivery and Tissue Support by STANLEY DARMA on Nov 15, 2012 • 10:52 am 0 inShare Left: A fully collapsed square-shaped cryogel rapidly regains its original memorized shape, size, and volume upon hydration. Right: Photos show the placement of a cryogel inside a 1-mL syringe, and the recovery of a square gel after injection through a normal 16-gauge needle. (Images courtesy of Sidi Bencherif.) Bioengineers at Harvard School of Engineering and Applied Sciences have come up with…. Read More → ...
Materials and Methods. Microorganism, media and cultivation. The R. wratislawiensis BN38, employed in this study was isolated from soil polluted with hydrocarbons by a standard enrichment technique (Tuleva et al., 2008). Minimal salt medium (MSM) with the following composition (g/l): K2HPO4.3H2O, 4.8; KH2PO4, 1.5; (NH4)2SO4, 1.0; MgSO4.7H2O, 0.2; supplemented with trace element solution (mg/l): CaCl2.2H2O, 2.0; MnCl2.4H2O, 0.4; NiCl2.6H2O, 0.4; ZnSO4.7H2O, 0.4; FeCl3.6H2O, 0.2; Na2MoO4.2H2O, 0.2 and phenol and n-hexadecane at 500 mg/l, unless otherwise mentioned, was used. The pH of the medium was adjusted to 7.0. The MSM was solidified as MSM phenol agar by addition of 1.8 % agar when necessary. Cultures grown on MSM agar supplemented with 500 mg/l phenol were used to inoculate 500 ml Erlenmeyer flasks, containing 100 ml liquid MSM. At each cycle MSM was supplemented to 100 ml with fresh sterile medium without cell transfer and only phenol was added. Cultures were incubated during the long-term ...
Pulse wave imaging (PWI) is an ultrasound-based method to visualize the propagation of pulse wave and to quantitatively estimate regional pulse wave velocity (PWV) of the arteries within the imaging field of view (FOV). To guarantee the reliability of PWV measurement, high frame rate imaging is required, which can be achieved by reducing the line density of ultrasound imaging or transmitting plane wave at the expense of spatial resolution and/or signal-to-noise ratio (SNR). In this study, a composite, full-view imaging method using motion matching was proposed with both high temporal and spatial resolution ...
Eichhorn, T.; Ivanov, A.E.; Dainiak, M. B.; Leistner, A.; Linsberger, I.; Jungvid, H.; Mikhalovsky, S. V.; Weber, V. (2013). Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites from blood. Journal of Chemistry, 2013: 348412 ...
The present invention provides a composition that softens at a predetermined temperature, preferably between about 20 C. and 90 C., and more preferably between about 20 C. and about 62 C., comprising at least one block copolymer having at least two thermal transition temperatures. The composition is characterized by at least two thermal transition temperatures, one of which is a predetermined lower transition temperature, preferably between about 20 C. to 90 C., and more preferably between about 20 C. to about 62 C., and one of which is an upper transition temperature. The present invention also provides a method of making the composition, a method of making biomedical materials and articles, and toys and toy components, with shape-memory properties from the composition, and biomedical materials and articles, and toys and toy components, with shape-memory properties made from the composition.
In this study, one type of oak galls (galls of Quercus macrenthera, QMG) was used as tannin source for the production of tannic acid-based cryogels (CRGs). QMG-CRGs were characterized with scanning electron microscopy and ...
Available literature values for T1 are approximately. 400 ms, 600 ms, 800 ms and 1100 ms at 1 T, 1.5 T, 1.9 T and 3 T, respectively [16] and [21]. Our value of T1 of 1656 ms measured at 7 T confirms the overall trend of increasing T1 with field strength. For T2, there appears to be little change with field strength. The observed fall in T1 and T2 with the number of freeze-thaw cycles also confirms previous reports [16] and [17], although only the T1 values for two and four cycles reached statistical significance. Available see more literature values for myocardial T1 are 1300 ms in rat at 4.7 T [22] and 952 ms in mouse at 9.4 T [23], rather lower than our PVA Cryogel phantoms. However, our primary design goal was to generate realistic myocardial motion rather than exact matching of relaxation times. Use of a pure sinusoidal flow from the pump resulted in eventual collapse. of the phantom at end systole, so that an offset sinusoid was used. In practice, the amplitude and degree of offset were ...
Our group brings together researchers investigating various aspects of cell organisation and dynamics. A major focus is to understand the mechanisms underlying the biosynthesis, targeting and trafficking of proteins within the cell. We also investigate membrane and cytoskeletal dynamics, intracellular ion homeostasis and the cellular processes responsible for plant growth and development. A major goal is to decipher how defects in these processes leads to disease.
Mouse eyes were immediately enucleated from euthanized animals, lenses were dissected in PBS and then immersed into 4% paraformaldehyde (PFA) in PBS at 37°C for 30 minutes. The fixed lenses were washed three times with PBS then sectioned into 150-μm slices with a vibratome (Leica VT1000 S; Leica, Wetlar, Germany). The slices were postfixed for 2 minutes in 4% PFA in PBS then washed three times with PBS before immunohistochemical analysis. A rabbit antibody against the intracellular loop of Cx46,26 a rabbit antibody against the C-terminal region of Cx50,27 a rabbit anti-βDystroglycan (anti-βDys) antibody (MANDAG2[7D11]; Developmental Studies Hybridoma Bank, Iowa City, IA, USA), and a rabbit anti-ZO-1 antibody (40-2200; Thermo-Fisher, Waltham, MA, USA) were used. Antigen retrieval was performed on sections destined for antibody labeling with the exception of anti-Cx50 labeling. The sections were placed in citrate buffer (10 mM sodium citrate, 0.05% vol/vol Tween 20) at 80°C for 30 minutes ...
Basin simulators have been used previously for deriving subsalt velocity models with the use of a correlation to relate effective stress to velocity. We build on this, and the work of others, to use physical models to relate porosity to velocity for migrating seismic data. This process yields a physically realizable isotropic velocity model that is consistent with the geologic model and matches the tomographic velocity model above salt and in regions where the tomographic velocity estimate is accurate. We then use a geomechanical simulator to model the stress distribution in and around allochthonous salt where material properties between salt and sediment change. Our stress model is the basis for an anisotropic velocity model using Murnaghans theory for finite elastic deformation. This formulation, with bounds placed on the elastic coefficients, leads to significant imaging improvements adjacent to salt. ...
Qianxiao Li: Free-energy-like concepts for nonequilibrium systems; Cheng Tai: Video Super-Resolution via Adaptive Wavelet Frames and Elastic Deformations ...
The Allen Cell Explorer website combines large-scale 3-D imaging data, the first application of deep learning to create predictive models of cell organization, gene edited human stem cell lines and a growing suite of powerful tools.
Cells are the structural and functional units of all living organisms. Some organisms, such as bacteria, are unicellular, consisting of a single cell. Other organisms, such as humans, are multicellular, or have many cells - an estimated 100,000,000,000,000 cells! Each cell is an amazing world unto itself: it can take in nutrients, convert these nutrients into energy, carry out specialized functions, and reproduce as necessary. Even more amazing is that each cell stores its own set of instructions for carrying out each of these activities. *Cell Organization* Before we can discuss the various components of a cell, it is important to ...
article{c02feb63-0c75-498d-9b63-6043d6df0ab2, abstract = {Background: Phage Display technology is a well established technique for high throughput screening of affinity ligands. Here we describe a new compact chromato-panning procedure for selection of suitable binders from a phage peptide display library. Results: Both phages and E. coli cells pass non-hindered through the interconnected pores of macroporous gel, so called cryogel. After coupling a ligand to a monolithic cryogel column, the phage library was applied on the column and non-bound phages were washed out. The selection of strong phage-binders was achieved already after the first panning cycle due to the efficient separation of phage-binders from phage-non-binders in chromatographic mode rather than in batch mode as in traditional biopanning procedures. E. coli cells were applied on the column for infection with the specifically bound phages. Conclusion: Chromato-panning allows combining several steps of the panning procedure ...
Shape-memory materials are featured by their ability to recover their original shape from a significant and seemingly plastic deformation when a particular stimulus is applied, which is known as the shape-memory effect.17-20,39-41 Shape-memory materials have been utilized in many fields, from aerospace engineering (e.g., in deployable structures and morphing wings) to medical devices (e.g., in stents and filters). Figure 1.3c and d show an example of a reversible bidirectional shape-memory free-standing copolymer network with two types of crystallizable domains that is capable of a fully reversible bidirectional shape-memory effect.41 This copolymer network is made of a multiphase copolyester urethane and consists of one set of crystallizable domain that determines the shape-shifting geometry, while the other domain of the network provides the thermally controlled actuation capability. This reversible bidirectional shape-memory technology can be inspirational to the design of many smart devices ...
This valve for gases, liquids, or powdery materials has an extremely simple and low-cost structure. Opening and closing functions are generated by using shape-memory wires, which move a diaphragm shutter element. The shape memory can reshape the diaphragm to lift away from the closed position. Then, with the change of temperature or current, it can return back to the closed position. This open/shut movement can be simple for on/off fluid requirements. It can also be rapid to effect displacement of a fluid. Particular positioning of shape-memory elements guarantees deicing functionality as resistance along the alloy can generate heat to prevent freezing.
According to a preferred embodiment of the invention, the window 4 has its bottom edge coupled to a driven member 7, in the form of a horizontal bar, which is controlled by the transmission 6. The bar 7 is provided with a seat in which the window 4 is slidably mounted so as to be able to perform a slight vertical movement with respect to the bar 7. The bar 7 carries a pair of cams 8, which are mounted articulated on the bar 7 and which can be brought from a horizontal, inoperative, position to a vertical, operative, position (in which they raise the window 4 by a small amount) by means of a shape-memory wire 9. Shape-memory alloys are known and have been used for some time. They are characterized by the property of changing state when a threshold temperature is exceeded. In the specific case of a shape-memory wire, the latter can be prearranged for reducing in length when its temperature of transition is exceeded. In the case in point, heating of the shape-memory wire 9 is obtained by causing it ...
A deformation sensor, which has excellent workability and a high degree of freedom in shape design and which can detect deformation and load in a wide area of components and portions, has a main body of sensor, electrodes which are connected to the main body of sensor and can output electric resistances, and a restraining component which restrains elastic deformation of at least a part of the main body of sensor. The main body of sensor has an elastomer, and spherical conductive fillers which are blended into the elastomer at a high filling rate in an approximately single-particle state, and is elastically deformable. In the main body of sensor, as an elastic deformation increases, the electric resistance increases.
An initial stress within a solid can arise to support external loads or from processes such as thermal expansion in inert matter or growth and remodelling in living materials. For this reason, it is useful to develop a mechanical framework of initially stressed solids irrespective of how this stress formed. An ideal way to do this is to write the free energy density psi in terms of initial stress tau and the elastic deformation gradient F, so we write psi = psi(F, tau). In this paper, we present a new constitutive condition for initially stressed materials, which we call the initial stress symmetry (ISS). We focus on two consequences of this condition. First, we examine how ISS restricts the possible choices of free energy densities psi = psi (F, tau) and present two examples of psi that satisfy the ISS. Second, we show that the initial stress can be derived from the Cauchy stress and the elastic deformation gradient. To illustrate, we take an example from biomechanics and calculate the optimal ...
Dec. 23, 2012 ? Scientists at The University of Manchester have identified how cells know which way up they need to be. The discovery could help in the fight against cancer because in the early stages of the disease the cells become disorganised.. Professor Charles Streuli and Dr Nasreen Akhtar of the Wellcome Trust Centre for Cell-Matrix Research have conducted new research that leads to a better understanding of cell polarity. Properly organised tissues are vital to maintaining functional organs and a healthy body. Part of being organised includes cells being in the correct position within the tissue and the right way up, because the top and bottom of cells have different functions.. The extracellular matrix (ECM) is a layer of protein rich material that surrounds tissues and helps to design and shape all of our organs. Previous studies have demonstrated that the ECM sticks to the cells and guides them into the right position. What hadnt been identified is how the ECM communicates that ...
This highly regarded hardcover engineering manual is mainly concerned with three important aspects of elasticity theory: finite elastic deformations, complex va
In some cases when the generated stress is immense, there is a rapid energy transfer through the dense and ordered packing of molecular single crystals and they are self-actuated by elastic deformation and/or by a ballistic event. This self-actuation phenomenon of crystals is termed thermosalient effect (Hüpf-Effekt) and is extremely rare propensity of certain crystalline solids capable of bending, twisting, curling, rolling or locomotion [2]. These systems are a prototype materials for novel, environmentally clean and efficient thermal-to-mechanical energy transformation. The capability of rapid energy transfer through the dense and ordered packing of single crystals evolves as a new platform for efficient dynamic elements, including artificial tissues and microfluidic elements. The fast energy transfer secured by efficient coupling between the thermal energy and mechanical energy stand as their main assets towards the design of fast actuators. The thermosalient effect is often accompanied ...
Zhu, X.L., Zhang, Y., Chandra, D., Cheng, S.C., Kikkawa, J.M. and Yang, S. Two-dimensional photonic crystals with anisotropic unit cells imprinted from poly(dimethylsiloxane) membranes under elastic deformation. Appl. Phys. Lett. 93, doi:10.1063/1.3006061 (2008). * (Selected to November 10, 2008 issue of Virtual J. Nanoscale Sci. & Tech., Am. Inst. Phys. & Am. Phys. Soc ...
CIC energiGUNE researchers have developed a hierarchically graphitized carbon foam that has an interconnected microporous structure.
While officials in the executive branch, members of Congress and senior congressional staffers spin in and out of the private and public sectors, so too does privilege, power, access and, of course, money.
A full selection of Crown Princess images, showing you all the cabins, restaurants, bars and amenities. Including external Crown Princess photos.
A novel minicolumn chromatographic method to monitor the production of inclusion bodies during fermentation and an enzyme-linked immunosorbent assay (ELISA) system allowing direct analysis of the particles with surface-displayed antigens are described. A 33-kDa protein containing 306 amino acids with three sulfur bridges produced as inclusion bodies was labeled with polyclonal antibodies against 15 amino acid (anti-A15) and 17 amino acid (anti-B17) residues at the N- and C-terminal ends of the protein, respectively. Labeled particles were bound to macroporous monolithic protein A-cryogel adsorbents inserted into the open-ended wells of a 96-well plate (referred to as protein A-cryogel minicolumn plate). The concept behind this application is that the binding degree of inclusion bodies from lysed fermentation broth to the cryogel minicolumns increases with an increase in their concentration during fermentation. The technique allowed us to monitor the increase in the production levels of the ...
This Cell Organization Worksheet is suitable for 9th Grade. In this cell organization worksheet, 9th graders conduct an experiment to create a three-dimensional model of a cell. Then they determine what items used from the list provided on cell parts and their various functions.
Effects of silica-gentamicin nanohybrids on osteogenic differentiation of human osteoblast-like SaOS-2 cells Wei He,1 Dina A Mosselhy,2,3 Yudong Zheng,1 Qingling Feng,4 Xiaoning Li,4 Xing Yang,4 Lina Yue,1 Simo-Pekka Hannula2 1School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, Peopleâ s Republic of China; 2Department of Chemistry and Materials Science, School of Chemical Engineering, Aalto University, Espoo, Finland; 3Microbiological Unit, Fish Diseases Department, Animal Health Research Institute, Giza, Egypt; 4State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, Peopleâ s Republic of China Introduction: In recent years, there has been an increasing interest in silica (SiO2) nanoparticles (NPs) as drug delivery systems. This interest is mainly attributed to the ease of their surface functionalization for drug loading. In orthopedic applications, gentamicin-loaded SiO2
Cell polarity is the property of cells to be spacially oriented in a tissue or organ. Loss of cell polarity is a hallmark of cancer and is associated with more aggressive tumours. In this grant, we propose experiments to understand a new family of proteins that act on cell polarity and proliferation to prevent cancer. We will study how the protein hScrib regulates the behaviour of breast cancer cells and assess whether alterations in hScrib are important for cancer development ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Although most materials slightly expand when heated, there is a new class of rubber-like material that not only self-stretches upon cooling; it reverts back to its original shape when heated, all without physical manipulation.
Flexible displays, electronics and even batteries are currently being tested and will be part of our daily lives in a matter of years. The technology also holds tremendous promise for medical research and could contribute to treatment of Alzheimer's disease and a host of other conditions. But first, you need to find appropriate materials.
In this work we have demonstrated a new approach to generate micropatterns on the sidewalls of polystyrene (PS) microchannels. The PS used is a thermal sha
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i would like to optimize over elastic deformation of a body (finding the best deformation in some sens), under the constraint that we never reach the elastic limit. In the optimization procedure, i am wondering if i should go over all points of the body and check if the constraint is verified, or if it is sufficient to check on the surface. This would reduce the computational complexity of the optimization ...
|p style=text-indent:20px;|We consider the model problem of an elastic beam vibrating between two stops. More precisely the beam is clamped at its left end while its right end may undergo contact and collision events with two stops. We model the interaction between the beam and the stops either with Signorini complementarity conditions when the stops are perfectly rigid or with a normal compliance contact law allowing some penetration within the stops and given by a linear relationship between the shear stress and the penetration at some positive power |inline-formula||tex-math id=M1|\begin{document}$ \beta $\end{document}|/tex-math||/inline-formula| when contact occurs.|/p||p style=text-indent:20px;|Motivated by computational issues we study the evolution of the energy functional defined as the sum of the kinetic energy and the potential energy of elastic deformation of the beam. When contact is modelled with a normal compliance law we prove an energy conservation property. Then we interpret the
Abstract: The open arc welding robots have been used widely nowadays; however, the elastic deformations of every inner link inevitably affect the welding quality. In this paper, it proposes an effective method of service reliability assessment for the rigidity-flexibility coupling open arc welding robot. Firstly, a parametric virtual model of the robot is built in ADAMS/View-AutoFlex module. Secondly, the stochastic errors generated in the working process are simulated by a program created from pseudo-random numbers which have been written by multiplicative congruence method. Lastly, Monte Carlo sampling calculation is implemented for the virtual model, and large sample data of the dynamic characteristics in welding process are obtained and used to calculate the service reliability of the welding robot. This method includes simplicity (no need to solve complex mathematic model) and high accuracy which make it highly promising for application in mechanism design ...
A heart pacemaker system has an electrode line with a proximal end which is introduced into a connector of the pacemaker housing, and a distal end having an electrode head attachable to the heart of a user. One or more of the distal or proximal ends of the electrode line, the connector, or a region of the electrode line are provided with a component consisting of shape-memory metal. These components have a first shape at temperatures different from body temperature, and assume a second shape when at body temperature. The shape-memory metal component, if disposed at the proximal end of the electrode line or at the connector, is arrnaged to provide a firm mechanical and electrical connection of the electrode line with the pacemaker housing upon the change of shape of the component. The shape-memory metal component, if disposed at the distal end, is arranged to assist in providing, either directly or indirectly, a reliable, mechanical and electrical connection of the electrode line to the heart upon the
Today the US Patent & Trademark Office published a pair of patent applications relating to wireless charging devices like an Apple Pencil and an Apple Watch and more importantly a new haptic feedback system for Apple Watch that under consideration that will introduce an actuation member formed from a shape-memory alloy (SMA). The new material will allow iPhone, iPad and Apple Watch teams to reduce some of the bulk of each device due to this next-gen haptic feedback device could be made much smaller.
Intermediate two-dimensional scanning with a three-dimensional scanner to speed registration | Proximity sensor device | Radar system and method | Device and method for judging likelihood of collision between vehicle and target, vehicle collision avoidance... | Radar device and method of processing signal |
Lipid bilayers form the boundaries of the cell and its organelles. Many physiological processes, such as cell movement and division, involve bending and folding of the bilayer at high curvatures. Currently, bending of the bilayer is treated as an elastic deformation, such that its stress-strain response is i
The analysis of rubber-like materials undergoing large elastic deformations is a key topic in field of active polymers, like ionic polymers, hydrogels and nematic elastomers, as well as in biomechanics, for soft tissues. For biomechanics, the hot issue relays in the development of mathematical-physical models that are able to describe the behaviour of physiological processes involving highly deformable tissues, like the skin or the muscles, or hard tissue as cartilage and bones. Such bio-mechanical models and their validation through experiments in vivo or in vitro can be helpful for better understanding physiological processes, for the planning of surgical interventions, or even for designing advanced prosthetic devices. In our case, we focused on the development of a model that describes the contraction of cardiac tissue based on the notion of active distortions. Then, our model has been implemented in a computational code in order to asses its performance through a series of numerical ...
At the California Institute of Technology (F. Cirak, M. Ortiz) and at Rutgers University (A. M. Cuitiño ) further sophisticated computer calculations on the elastic deformations of an ultra-thin foil were undertaken. The resulting pictures were quite realistic. The fact that the foil folds very irregularly (first occurring when the plate holding the foil experiences a temperature difference of only one degree) is caused by the way in which it was manufactured. The thin foil is stretched over an approximately four-millimeter hole in a platinum holder and attaches itself to the platinum through adhesion alone. Although the foil over the hole is self-supporting, it is not stretched in a uniform manner. This tension works, at first, to stabilize the smooth form of the foil, so that with small temperature increases no folds appear. The computer simulations showed that if the samples were perfectly symmetrical, they would begin to bend with the smallest temperature increases. If the temperature ...
A cart for weighing small animals with the cart having a torsional undercarriage mechanism that directs the weight of an animal in a weighing pen through a single tension support member wherein the elastic deformation of the single tension support member is measured with an electrical resistance strain gauge mounted on the tension support member and a conventional digital strain gauge read-out device.
NEW YORK (Reuters Health) - Women on chemotherapy for breast cancer may have tiny memory and thinking impairments compared with cancer-free women more than 20...
"Chapter 16 Direct Capture of His6-Tagged Proteins Using Megaporous Cryogels Developed for Metal-Ion Affinity Chromatography" ...
Structure-Property Relationships of Cryogels Oguz Okay, Vla ... A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic ... Rocco Di Girolamo Cryogels via UV Irradiation Technique Petar D. Petrov, Christo B. Tsvetanov Inorganic Cryogels Oleg A. ... Shlyakhtin Cryogels for Biotechnological Applications Bo Mattiasson Poly(vinyl alcohol) Cryogels for Biomedical Applications ... A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic Principles of Cryotropic Gelation Vladimir I. Lozinsky, Oguz ...
The use of superporous p(AAc (acrylic acid)) cryogels as support for Co and Ni nanoparticle preparation and as reactor in H-2 ... Cryogels showed better catalytic activity than conventional hydrogels in the hydrolysis reaction, and have a higher TOF ( ... Superporous p(AAc) cryogels and conventional hydrogels were prepared via free radical polymerization technique at low (-18 ...
Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites ...
Uranyl Ions Removal by Quercus macrenthera Galls Extract-Based Cryogels with Extreme Characteristics Bagda, Esra; Zonuz, Nuray ... was used as tannin source for the production of tannic acid-based cryogels (CRGs). QMG-CRGs were characterized with scanning ...
Usually, cryogels possess spongy-like structure of huge pores (50-200 µm) containing free water surrounded by thin walls and, ... Polymeric cryogels as promising materials of biotechnological interest. Trends Biotechnol. 21:445-451. ... The cryogels were extracted in distilled water for seven days, frozen and freeze dried in an "Alpha 1-2 Freeze Drier" (Martin ... Super-macroporous polymer cryogels are an interesting class of materials due to their unique heterogeneous open porous ...
Structure-Property Relationships of Cryogels Oguz Okay, Vla ... A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic ... Rocco Di Girolamo Cryogels via UV Irradiation Technique Petar D. Petrov, Christo B. Tsvetanov Inorganic Cryogels Oleg A. ... Shlyakhtin Cryogels for Biotechnological Applications Bo Mattiasson Poly(vinyl alcohol) Cryogels for Biomedical Applications ... A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic Principles of Cryotropic Gelation Vladimir I. Lozinsky, Oguz ...
... Lozinsky, Vladimir; Plieva, Fatima LU ; Galaev, Igor LU and Mattiasson, ... immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. Cryotropic gel formation ... immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. Cryotropic gel formation ... immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. Cryotropic gel formation ...
... Wim Van Camp UGent, Tuğba Dışpınar, ... "Chemical Modifications of Cryogels Verified Using High-resolution Mass NMR Spectroscopy." In Dresden Polymer Discussion, 12th, ... "Chemical Modifications of Cryogels Verified Using High-resolution Mass NMR Spectroscopy." Dresden Polymer Discussion, 12th, ... Van Camp W, Dışpınar T, Dervaux B, Du Prez F, Martins J, Fritzinger B. Chemical modifications of cryogels verified using high- ...
Çavuş A, Baysal Z, Alkan H (2013) Preparation of poly(hydroxyethyl methacrylate) cryogels containing l-histidine for insulin ... Lozinsky VI, Plieva FM, Galaev IY, Mattiasson B (2002) The potential of polymeric cryogels in bioseparation. Bioseparation. 10: ... The comparative investigation on synthesis, characterizations of silver ion-imprinting and non-imprinting cryogels, their ...
The behaviour of gels upon coagulation and the swelling of cryogels in water were analysed. An anomalous high swelling at cross ... The behaviour of gels upon coagulation and the swelling of cryogels in water were analysed. An anomalous high swelling at cross ... The behaviour of gels upon coagulation and the swelling of cryogels in water were analysed. An anomalous high swelling at cross ... Ciolacu, D, Rudaz, C, Vasilescu, M & Budtova, T 2016, Physically and chemically cross-linked cellulose cryogels: Structure, ...
These macroporous cryogels based on hyaluronic acid (HA) or alginate are formed by cryogenic polymerization of methacrylated HA ... This invention focuses on covalent attachment of a wide range of biomolecules onto pre-formed 3D biomaterial-based cryogels. ... protein complexes and polysaccharides to these pre-formed cryogels. This established presence of co-monomers during ... these cryogels can easily be applied in vivo. ... strategy for covalent grafting of biomolecules to cryogels. ...
DSCs based on BC cryogels had an initially higher performance and similar stability compared to those of the reference cells. ... When compared to reference cells, CNF and ChNF cryogels produced higher initial performance, but they underwent a faster ...
This study suggested very low capacities of the cryogels for the protein due to low coupling sites on the matrix. Taking into ... Development of chromatographic bioseparations based on lectins and supermacroporous affinity cryogels. Raletjena, Moloko Ivonne ...
Fingerprint Dive into the research topics of Cryogels: morphological, structural and adsorption characterisation. Together ...
Nanocellulose/bioactive glass cryogels as scaffolds for bone regeneration. Filipe V. Ferreira, Lucas P. Souza, Thais M. M. ...
Feasibility of ceramic-polymer composite cryogels as scaffolds for bone tissue engineering. *Rodriguez-Lorenzo L ...
In conclusion, the cryogels produced in this study were found to be biocompatible and, by alteration of the fibrinogen content ... In conclusion, the cryogels produced in this study were found to be biocompatible and, by alteration of the fibrinogen content ... In conclusion, the cryogels produced in this study were found to be biocompatible and, by alteration of the fibrinogen content ... In conclusion, the cryogels produced in this study were found to be biocompatible and, by alteration of the fibrinogen content ...
Biosurfactant Production by Pseudomonas aeruginosa BN10 Cells Entrapped in Cryogels. Christova, Nelly / Petrov, Petar / ...
8.6 Cryogels 334. 8.7 Process Technology 336. 8.8 Applications 338. References 345 ...
46.Henderson, T.M.A., Ladewig, K., Haylock, D.N., McLean, K.M., and OConnor, A.J.: Cryogels for biomedical applications. J. ...
Direct Capture of His6-Tagged Proteins Using Megaporous Cryogels Developed for Metal-Ion Affinity Chromatography ... A Novel Chromatographic Media: Histidine-Containing Composite Cryogels for HIgG Separation from Human Serum ... Ni(II) Chelated IDA Functionalized Poly(HEMA-GMA) Cryogels for Urease Adsorption ... Interpenetrating Polymer Network Composite Cryogels with Tailored Porous Morphology and Sorption Properties ...
Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites ... Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites ... Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites ... Macroporous composite cryogels with embedded polystyrene divinylbenzene microparticles for the adsorption of toxic metabolites ...
Polyaniline cryogels: Biocompatibility of novel conducting macroporous material HUMPOLÍČEK Petr RADASZKIEWICZ Katarzyna Anna ...
Activated carbon cryogels and related methods. US20110002086 *. Jul 1, 2010. Jan 6, 2011. Feaver Aaron M. Ultrapure synthetic ... Activated carbon cryogels and related methods. US8797717. May 20, 2013. Aug 5, 2014. University Of Washington. Electrodes and ... Activated carbon cryogels and related methods. US8293818. Apr 8, 2010. Oct 23, 2012. Energ2 Technologies, Inc.. Manufacturing ...
Kefiran cryogels as potential scaffolds for drug delivery and tissue engineering applications. last updated: 2020-08-06 ... Kefiran cryogels as potential scaffolds for drug delivery and tissue engineering applications. ...
Injectable nanocomposite cryogels for versatile protein drug delivery.. Koshy ST, Zhang DKY, Grolman JM, Stafford AG, Mooney DJ ... Injectable, Tough Alginate Cryogels as Cancer Vaccines.. Shih TY, Blacklow SO, Li AW, Freedman BR, Bencherif S, Koshy ST, ...
Hybrid alginate-based cryogels for life science applications Author(s): Barros, Alexandre António Antunes,Quraishi, Sakeena, ...
Activated carbon cryogels and related methods. US20110002086 *. 1 Jul 2010. 6 Ene 2011. Feaver Aaron M. Ultrapure synthetic ... Activated carbon cryogels and related methods. US8797717. 20 May 2013. 5 Ago 2014. University Of Washington. Electrodes and ... Activated carbon cryogels and related methods. US8293818. 8 Abr 2010. 23 Oct 2012. Energ2 Technologies, Inc.. Manufacturing ...
Adsorption of cellulase on poly(2-hydroxyethyl methacrylate) cryogels containing phenylalanine Authors: MURAT YAVUZ, OĞUZ ÇAKIR ...
Original Paper: Nano- and macroporous materials (aerogels, xerogels, cryogels, etc.). First Online: 25 April 2016. ...
Extracellular matrix-based cryogels for cartilage tissue engineering.. Han ME, Kim SH, Kim HD, Yim HG, Bencherif SA, Kim TI, ... Injectable Hyaluronic Acid-co-Gelatin Cryogels for Tissue-Engineering Applications.. Rezaeeyazdi M, Colombani T, Memic A, ...
2] Mattiasson, B. Cryogels for Biotechnological Applications. in Polymeric Cryogels (ed. Okay, O.) 245-281 (Springer Intnl Pub ... 1] Komarova, G. A. et al. Intelligent Gels and Cryogels with Entrapped Emulsions. Langmuir 24, 4467-4469 (2008). [ ... These chitosan derivatives cryogels exhibited loading ability, and the release of citral was pH- and temperature-dependent.. ... The pore size of the cryogels is around of 10 µm. The study of equilibrium swelling shows an abrupt decrement in water ...
Incorporation of decellularized extracellular matrix in cryogels for muscle regeneration (abstract). 10:00. Xutu Wang ( ...
Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals ...
  • Scanning electron microscopy of the composite cryogels revealed that the microparticles were covered by thin films of poly(vinyl alcohol) or agarose and thus were withheld in the monolith structure. (edu.kz)
  • This can be overcome by the development of composite cryogels. (rian.ie)
  • In this study, PVA/Biomacromolecule composite cryogels were produced with a two step physical crosslinking (cryogelation and coagulation bath treatment) in the presence of different additives and a novel procedure to produce cell encapsulated PVA cryogels was developed for vascular tissue engineering. (rian.ie)
  • Poly(AAm-GMA) cryogels were used as structural elements, whileGMA monomer served reactive epoxy groups for IDA immobilization. (ias.ac.in)
  • Reusability profile of the poly(AAm-GMA)-IDA-Cu$^{2+}$ cryogels was also studied and it was found that the synthesized cryogels could be used repeatedly for many times without any significant decrease on their adsorption capacity. (ias.ac.in)
  • For this, poly(AAm-MMA)cryogels were synthesized by free radical cryopolymerization technique and then, modified by $N$-acetylcysteine. (ias.ac.in)
  • In the present research, we fabricated cryogels consisting of methacrylated gelatin, methacrylated hyaluronic acid, and 4arm poly(ethylene glycol) acrylate (PEG-4A) by using cryopolymerization. (envisiontec.com)
  • Effect of immobilization on the activity of catalase carried by poly(HEMA-GMA) cryogels. (bioportfolio.com)
  • Thermoresponsive cryogels of poly(N-isopropylacrylamide) (PNIPAAm), synthesized by free radical polymerization (FRP), were reinforced by the addition of cellulose nanocrystals (CNCs). (diva-portal.org)
  • Here, an atomic force microscopy-based nanoindentation approach is adapted to quantify the local mechanical properties of biohybrid glycosaminoglycan poly(ethylene glycol) cryogels. (ipfdd.de)
  • These macroporous cryogels based on hyaluronic acid (HA) or alginate are formed by cryogenic polymerization of methacrylated HA or alginate polymers. (technologypublisher.com)
  • Macroporous cryogels containing mixtures of two key components of the dermal extracellular matrix, fibrinogen and collagen-derived gelatin, were evaluated for use as dermal tissue regeneration scaffolds. (edu.kz)
  • Cryogels showed better catalytic activity than conventional hydrogels in the hydrolysis reaction, and have a higher TOF (turnover frequency) value of 4.10 mol H-2 (mol catalyst min)(-1) compared to conventional hydrogels, due to its highly porous nature, short diffusion distances and fast response times. (comu.edu.tr)
  • This is a review discussing the production and properties of cryogels (from the Greek κριoσ (kryos) meaning frost or ice), immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. (lu.se)
  • article{83697e11-578b-49d7-a3be-c17fd175392b, abstract = {This is a review discussing the production and properties of cryogels (from the Greek κριoσ (kryos) meaning frost or ice), immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. (lu.se)
  • Superporous p(AAc) cryogels and conventional hydrogels were prepared via free radical polymerization technique at low (-18 degrees C) and moderate (40 degrees C) temperatures, respectively. (comu.edu.tr)
  • Various polymeric and polymer/protein hydrogels can be synthesized as cryogels at subzero temperatures. (science-community.org)
  • Injectable Hyaluronic Acid- co -Gelatin Cryogels for Tissue-Engineering Applications. (nih.gov)
  • In this study carrageenan-gelatin (natural polymers) cryogels were synthesized by using glutaraldehyde and 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride and N -hydroxysuccinimide (EDC-NHS) as crosslinking agent at optimum concentrations. (hindawi.com)
  • Supermacroporous carrageenan-gelatin cryogels showed efficient cell adherence and proliferation of Cos-7 cells which was examined by SEM. (hindawi.com)
  • This system provides a highly modular platform to functionalize 3D cryogel scaffolds, and owing to their syringe injectability, these cryogels can easily be applied in vivo. (technologypublisher.com)
  • Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. (harvard.edu)
  • These injectable cryogels will be especially useful for a number of clinical applications including cell therapy, tissue engineering, dermal filler in cosmetics, drug delivery, and scaffold-based immunotherapy, says Bencherif. (nanowerk.com)
  • Extracellular matrix-based cryogels for cartilage tissue engineering. (nih.gov)
  • Cryogels are characterized by high biocompatibility due to the use of biopolymeric or protein matrices. (science-community.org)
  • Ice-templated freeze-dried cryogels from tunicate cellulose nanocrystals with high specific surface area and anisotropic morphological and mechanical properties. (cea.fr)
  • PVA cryogelation is a physical hydrogel formation method, which yields cryogels with comparable mechanical properties to vascular tissue. (rian.ie)
  • Interconnected systems of macropores and sponge-like morphology are typical for cryogels, allowing unhindered diffusion of solutes of practically any size. (lu.se)
  • The unique macroporous morphology of cryogels, in combination with osmotic, chemical and mechanical stability, makes them attractive matrices for chromatography of large entities such as protein aggregates, membrane fragments, viruses, cell organells and even whole cells. (lu.se)
  • The invention provides cryogels whose porosity, pore size, pore connectivity, swelling agent concentration, and/or specific volume undergoes a change from a. (patents.com)
  • Cryogels are characterized by very broad pore size distribution from nanometers to hundreds of micrometers. (science-community.org)
  • In conclusion, the cryogels produced in this study were found to be biocompatible and, by alteration of the fibrinogen content, could be rendered more amenable to cellular infiltration. (edu.kz)
  • Cytotoxicity of the scaffolds was checked by MTT assay which showed that cryogels are biocompatible and act as a potential material for tissue engineering and regenerative medicine. (hindawi.com)
  • Most of the water present in spongy cryogels is capillary bound and can be removed mechanically by squeezing. (lu.se)
  • Northeastern researchers have developed a versatile and straightforward strategy to covalently couple activating antibodies, protein complexes and polysaccharides to these pre-formed cryogels. (technologypublisher.com)
  • This study suggested very low capacities of the cryogels for the protein due to low coupling sites on the matrix. (ul.ac.za)
  • Al-Lohedan, H. The resourcefulness of p(4-VP) cryogels as template for in situ nanoparticle preparation of various metals and their use in H 2 production, nitro compound reduction and dye degradation. (alfa.com)
  • The macroporous nature of cryogels is also advantageous for their application as matrices in the immobilization of biocatalysts operating in both aqueous and organic solvents. (lu.se)
  • Unconfined compression analysis showed elasticity and physical integrity of all cryogels, as these matrices regained their original length after 90% compressing from the original size. (hindawi.com)
  • The properties of cryogels can be regulated by the temperature of cryogelation, the time the sample is kept in a frozen state and freezing/thawing rates, by the nature of the solvent and by the use of soluble and insoluble additives. (lu.se)
  • Results: The addition of glycerol co-solvent induces favourable light transmission properties in normally opaque PVA cryogels, especially well-suited to the near-infrared light requirements of PNSB. (sun.ac.za)
  • Conclusion: Transparent PVA cryogels offer ideal properties as an immobilisation matrix for phototrophic bacteria and present a low-cost photobioreactor technology for the further advancement of biohydrogen from waste as a sustainable energy source, as well as development of alternative photo-bioprocesses exploiting the unique capabilities of purple non-sulfur bacteria. (sun.ac.za)
  • These cryogels also exhibited good in vitro degradation capacity at 37 °C within 4 weeks of incubation. (hindawi.com)
  • As chromatographic materials, cryogels can be used both in bead form and as spongy cylindrical blocks (monoliths) synthesized inside the chromatographic column. (lu.se)
  • However PVA cryogels are not suitable for cell attachment and proliferation alone. (rian.ie)
  • In contrast, conventional PVA cryogels require multiple cycles which compromise viability of entrapped organisms. (sun.ac.za)
  • New potential applications of cryogels are discussed. (lu.se)
  • Van Camp W, Dışpınar T, Dervaux B, Du Prez F, Martins J, Fritzinger B. Chemical modifications of cryogels verified using high-resolution mass NMR spectroscopy. (ugent.be)
  • Cryogels can be obtained through the formation of both physically and covalently cross-linked heterogeneous polymer networks. (lu.se)
  • The company's three basic product lines, high-temperature Pyrogels and mid- to low-temperature Spacelofts and Cryogels-all in the form of flexible blankets-were established in the company's early years and are now installed in industrial plants, steam distribution systems, buildings, pipelines, and much more all over the world. (techbriefs.com)
  • The glycerol co-solvent in transparent cryogels offered additional benefit by reinforcing physical interactions to the extent that only a single freeze-thaw cycle was required to form durable cryogels, extending utility beyond only phototrophic bioprocesses. (sun.ac.za)
  • DSCs based on BC cryogels had an initially higher performance and similar stability compared to those of the reference cells. (finnceres.fi)
  • The behaviour of gels upon coagulation and the swelling of cryogels in water were analysed. (aalto.fi)
  • Cryogels can absorb large amounts of water and characterized controlled swelling degree. (science-community.org)