Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTIGEN injection or infection with microorganisms containing the antigen.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
Assistance, such as money, food, or shelter, given to the needy, aged, or victims of disaster. It is usually granted on a temporary basis. (From The American Heritage Dictionary, 2d college ed)
Emergency care or treatment given to a person who suddenly becomes ill or injured before full medical services become available.
Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.
Procedures outlined for the care of casualties and the maintenance of services in disasters.
Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.
Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)
State of mind or behavior characterized by extreme skepticism and persistent opposition or resistance to outside suggestions or advice. (APA, Thesaurus of Psychological Index Terms, 1994)
The transmission and reproduction of transient images of fixed or moving objects. An electronic system of transmitting such images together with sound over a wire or through space by apparatus that converts light and sound into electrical waves and reconverts them into visible light rays and audible sound. (From Webster, 3rd ed)
The collection, preparation, and distribution of news and related commentary and feature materials through such media as pamphlets, newsletters, newspapers, magazines, radio, motion pictures, television, and books. While originally applied to the reportage of current events in printed form, specifically newspapers, with the advent of radio and television the use of the term has broadened to include all printed and electronic communication dealing with current affairs.
Those affective states which can be experienced and have arousing and motivational properties.
Activities concerned with governmental policies, functions, etc.
The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)
Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species.
Any waste product generated by a dental office, surgery, clinic, or laboratory including amalgams, saliva, and rinse water.
A serotype of the species California encephalitis virus (ENCEPHALITIS VIRUS, CALIFORNIA), in the genus ORTHOBUNYAVIRUS, causing human MENINGOENCEPHALITIS. This is the agent most responsible for California encephalitis (ENCEPHALITIS, CALIFORNIA), the most prevalent mosquito-borne disease recognized in the United States.
A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.
Inorganic or organic salts and esters of boric acid.
Inorganic compounds that contain fluorine as an integral part of the molecule.
Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
A high-molecular-weight polymeric elastomer derived from the milk juice (LATEX) of HEVEA brasiliensis and other trees and plants. It is a substance that can be stretched at room temperature to at least twice its original length and after releasing the stress, retract rapidly, and recover its original dimensions fully.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
A group I chaperonin protein that forms a lid-like structure which encloses the non-polar cavity of the chaperonin complex. The protein was originally studied in BACTERIA where it is commonly referred to as GroES protein.
Bovine respiratory disease found in animals that have been shipped or exposed to CATTLE recently transported. The major agent responsible for the disease is MANNHEIMIA HAEMOLYTICA and less commonly, PASTEURELLA MULTOCIDA or HAEMOPHILUS SOMNUS. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the LUNG. They are considered opportunistic pathogens following STRESS, PHYSIOLOGICAL and/or a viral infection. The resulting bacterial fibrinous BRONCHOPNEUMONIA is often fatal.
A usually four-wheeled automotive vehicle designed for passenger transportation and commonly propelled by an internal-combustion engine using a volatile fuel. (Webster, 1973)
Large vessels propelled by power or sail used for transportation on rivers, seas, oceans, or other navigable waters. Boats are smaller vessels propelled by oars, paddles, sail, or power; they may or may not have a deck.
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies.
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.
Antibodies produced by a single clone of cells.
Common name for many members of the FALCONIFORMES order, family Accipitridae, generally smaller than EAGLES, and containing short, rounded wings and a long tail.
Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger".
BIRDS that hunt and kill other animals, especially higher vertebrates, for food. They include the FALCONIFORMES order, or diurnal birds of prey, comprised of EAGLES, falcons, HAWKS, and others, as well as the STRIGIFORMES order, or nocturnal birds of prey, which includes OWLS.
Large members of the FALCONIFORMES order of birds, family Accipitridae, most especially the genera Aquila, Haliaeetus, Harpia, and Circaetus. They are characterized by their powerful talons, which carry long, curved, pointed claws and by their opposable hindtoe.
An order of diurnal BIRDS of prey, including EAGLES; HAWKS; buzzards; vultures; and falcons.

Highly sensitive quantitation of methamphetamine by time-resolved fluoroimmunoassay using a new europium chelate as a label. (1/8142)

A simple and highly sensitive time-resolved fluoroimmunoassay of methamphetamine (MA) using a new fluorescent europium chelate (BHHCT-Eu3+) as a label is described. Two variations of competitive immunoassay were attempted. In the first (one-step) assay, microtiter plates coated with anti-MA were used, and the new label was bound to a conjugate of bovine serum albumin and N-(4-aminobutyl)-MA (MA-BSA). In the second (two-step) assay, instead of the labeled MA-BSA, biotinylated MA-BSA and BHHCT-Eu3+-labeled streptavidin-BSA were used. The lowest measurable concentrations of MA for the one-step and the two-step methods were 1 ng/mL (25 pg/assay) and 1 pg/mL (25 fg/assay), respectively. These were 10 to 1000 times superior to the detection limits of MA in any other immunoassay. Intra-assay coefficient of variation was approximately 2-8% at eight different concentrations (n = 4). Analysis of 34 urine samples with the new method and conventional gas chromatography showed a good correlation (r = 0.954). The high detectability of the present assay also enabled segmental hair analysis with a few centimeters of a hair.  (+info)

The levels and bactericidal capacity of antibodies directed against the UspA1 and UspA2 outer membrane proteins of Moraxella (Branhamella) catarrhalis in adults and children. (2/8142)

The UspA1 and UspA2 proteins from Moraxella catarrhalis share antigenic epitopes and are promising vaccine candidates. In this study, the levels and bactericidal activities of antibodies in sera from healthy adults and children toward UspA1 and UspA2 from the O35E strain were measured. Human sera contained antibodies to both proteins, and the levels of immunoglobulin G (IgG) antibodies were age dependent. Adult sera had significantly higher titers of IgG than child sera (P < 0.01). The IgG3 titers to the UspA proteins were higher than the IgG1 titers in the adults' sera, while the IgG1 titers were higher than the IgG3 titers in the children's sera (P < 0.05). The IgG antibodies in the sera from 2-month-old children appeared to be maternally derived, since the mean titer was significantly higher than that in sera from 6- to 7-month-old children (P < 0.05). Serum IgA antibodies to both UspA1 and UspA2 were low during the first 7 months of age but thereafter gradually increased along with the IgG titers. Analysis of sera absorbed with UspA1 or UspA2 showed that the antibodies to UspA1 and UspA2 were cross-reactive with each other and associated with serum bactericidal activity. Examination of affinity-purified human antibodies confirmed that naturally acquired antibodies to UspA1 and UspA2 were bactericidal and cross-reactive. These results support using UspA1 and UspA2 in a vaccine to prevent M. catarrhalis infections.  (+info)

Autoantibodies to RNA polymerases recognize multiple subunits and demonstrate cross-reactivity with RNA polymerase complexes. (3/8142)

OBJECTIVE: To determine the subunit specificity of autoantibody directed to RNA polymerases (RNAP) I, II, and III, which is one of the major autoantibody responses in patients with systemic sclerosis (SSc). METHODS: Thirty-two SSc sera with anti-RNAP antibodies (23 with anti-RNAP I/III, 5 with anti-RNAP I/III and II, and 4 with anti-RNAP II alone) were analyzed by immunoblotting using affinity-purified RNAP and by immunoprecipitation using 35S-labeled cell extracts in which RNAP complexes were dissociated. Antibodies bound to individual RNAP subunits were eluted from preparative immunoblots and were further analyzed by immunoblotting and immunoprecipitation. RESULTS: At least 15 different proteins were bound by antibodies in anti-RNAP-positive SSc sera in various combinations. All 9 sera immunoprecipitating RNAP II and all 28 sera immunoprecipitating RNAP I/III recognized the large subunit proteins of RNAP II and III, respectively. Reactivity to RNAP I large subunits was strongly associated with bright nucleolar staining by indirect immunofluorescence. Affinity-purified antibodies that recognized a 62-kd subunit protein cross-reacted with a 43-kd subunit protein and immunoprecipitated both RNAP I and RNAP III. Antibodies that recognized a 21-kd subunit protein obtained from sera that were positive for anti-RNAP I/III and II antibodies immunoprecipitated both RNAP II and RNAP III. CONCLUSION: Anti-RNAP antibodies recognize multiple subunits of RNAP I, II, and III. Moreover, the results of this study provide the first direct evidence that antibodies that recognize shared subunits of human RNAPs or epitopes present on different human RNAP subunits are responsible for the recognition of multiple RNAPs by SSc sera.  (+info)

Human geranylgeranyl diphosphate synthase. cDNA cloning and expression. (4/8142)

Geranylgeranyl diphosphate (GGPP) synthase (GGPPSase) catalyzes the synthesis of GGPP, which is an important molecule responsible for the C20-prenylated protein biosynthesis and for the regulation of a nuclear hormone receptor (LXR.RXR). The human GGPPSase cDNA encodes a protein of 300 amino acids which shows 16% sequence identity with the known human farnesyl diphosphate (FPP) synthase (FPPSase). The GGPPSase expressed in Escherichia coli catalyzes the GGPP formation (240 nmol/min/mg) from FPP and isopentenyl diphosphate. The human GGPPSase behaves as an oligomeric molecule with 280 kDa on a gel filtration column and cross-reacts with an antibody directed against bovine brain GGPPSase, which differs immunochemically from bovine brain FPPSase. Northern blot analysis indicates the presence of two forms of the mRNA.  (+info)

Serum dilution neutralization test for California group virus identification and serology. (5/8142)

The serum dilution neutralization test was evaluated for serological diagnosis of California group arbovirus infections and identification of virus isolates. The technical advantages and the degree of subtype specificity of the serum dilution neutralization test over the hemagglutination inhibition test and the complement fixation test were demonstrated with paired specimens from human cases, single human survey sera, and sentinel rabbit sera. Twenty-one virus isolates from various geographical areas of the United States were also used to evaluate the efficacy of the serum dilution neutralization test for specific virus identification.  (+info)

Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies. (6/8142)

Endoglin (EDG, CD105) is a proliferation-associated antigen on endothelial cells. In this study, two new anti-EDG monoclonal antibodies (mAbs) Y4-2F1 (or termed SN6j) and P3-2G8 (SN6k) were generated and used for treating distinct preformed tumors. These mAbs, both IgG1-kappa antibodies, cross-reacted weakly with mouse endothelial cells but defined epitopes different from the epitope defined by a previously reported anti-EDG mAb K4-2C10 (B. K. Seon et al., Clin. Cancer Res., 3: 1031-1044, 1997). SN6j and SN6k reacted strongly with human endothelial cells and vascular endothelium of malignant human tissues but showed no significant reactivity with tumor cells per se. The deglycosylated ricin A chain (dgRA) conjugates of the two mAbs showed a weak but specific cytotoxic activity against murine endothelial cells in vitro. In the therapeutic studies, severe combined immunodeficient mice were inoculated s.c. with MCF-7 human breast cancer cells and left untreated until palpable tumors of distinct size (4-6 mm in diameter) appeared. Mice with the distinct tumors were treated by i.v. administration of individual anti-EDG conjugates, unconjugated mAbs, or a control conjugate. Long-lasting complete regression of the tumors was induced in the majority of tumor-bearing mice (n = 8 for each conjugate) when 40 microg of the individual conjugates were administered three times via the tail vein. It is remarkable that the tumors remained regressed without further therapy for as long as the mice were followed (i.e., 100 days). Control conjugate did not induce regression of the tumors in any of the treated mice, although weak nonspecific effects were observed in some of the mice (n = 8). The effects of unconjugated mAbs were small with the dose used, i.e., 34 microg three times. The anti-EDG conjugates showed antiangiogenic activity in the dorsal air sac assay in mice. The results suggest good potential of these conjugates for the clinical application.  (+info)

A new picornavirus isolated from bank voles (Clethrionomys glareolus). (7/8142)

A previously unknown picornavirus was isolated from bank voles (Clethrionomys glareolus). Electron microscopy images and sequence data of the prototype isolate, named Ljungan virus, showed that it is a picornavirus. The amino acid sequences of predicted Ljungan virus capsid proteins VP2 and VP3 were closely related to the human pathogen echovirus 22 (approximately 70% similarity). A partial 5' noncoding region sequence of Ljungan virus showed the highest degree of relatedness to cardioviruses. Two additional isolates were serologically and molecularly related to the prototype.  (+info)

Serological classification of Pseudomonas aeruginosa by a slide agglutination test. (8/8142)

Serological classification of Pseudomonas aeruginosa by the slide agglutination test with live organisms was studied, based on the O antigen schema adopted by the international expert panel sponsored by the Subcommittee on Pseudomonas and Related Organisms of the International Committee on Systematic Bacteriology. The typing results obtained by the slide test with well-absorbed O sera were identical to those obtained by the conventional tube agglutination test with autoclaved organisms. Most O antigens occur singly; but O2, O5, and O16 occur in four combinations. Antigens O13 and O14 are closely related, as are O7 and O8, and it would be convenient to classify organisms possessing these antigens collectively as O7,8 and O13,14.  (+info)

Jeggo, M H. and Wardley, R C., Generation of cross-reactive cytotoxic t lymphocytes following immunization of mice with various bluetongue virus types. (1982). Subject Strain Bibliography 1982. 3115 ...
In an assay for a target nucleotide sequence employing hybridization with a target probe nucleotide sequence, cross reaction between the target probe and a non-target nucleotide sequence, capable of hybridizing with the target probe, is prevented or diminished by introducing, at some point during the hybridization, a non-target probe which hybridizes preferentially with the non-target nucleotide sequence. The melting temperature for the non-target probe/non-target nucleotide sequence hybrid is preferably greater than that of the target probe/non-target sequence hybrid. The hybridization can be carried out under isothermal conditions or preferentially with gradual cooling.
3041.2.4 Ski Cross Reaction Time For the ski cross qualification and final, a reaction time will be measured and displayed at the start. The time will be measured from when the start gate is opened until a point 10 meters from the Start Gate. The reaction time will be measured and displayed to the 1/100ths of a second. This is required for World Cups, World Championships and Olympic Winter Games. ...
TY - JOUR. T1 - Immunological cross reaction between calf and Drosophila histones. AU - Bustin, M.. AU - Reeder, R. H.. AU - McKnight, S. L.. PY - 1977. Y1 - 1977. UR - UR - M3 - Article. C2 - 856814. AN - SCOPUS:0017387756. VL - 252. SP - 3099. EP - 3101. JO - Journal of Biological Chemistry. JF - Journal of Biological Chemistry. SN - 0021-9258. IS - 9. ER - ...
Heterosubtypic immunity, defined as cross-reactive immune responses to influenza virus of a different serotype than the virus initially encountered, was investigated in association with virus-specific cytotoxic T lymphocyte (CTL) responses induced in systemic and mucosa-associated lymph nodes after immunization via different routes. Mice immunized by the pulmonary route with live nonpathogenic influenza virus, strain Udorn (H3N2), survived challenge with mouse-adapted pathogenic influenza virus, strain PR/8/34 (H1N1). These mice developed strong heterosubtypic CTL responses in spleen, cervical lymph nodes (CLN), and mediastinal lymph nodes (MLN). Alternately, only 20% of mice immunized intravenously, intraperitoneally, or intranasally survived the challenge; all of these developed CTL responses in spleen and CLN, but not in MLN. Direct correlation between short-term and long-term memory heterosubtypic CTL responses induced in MLN and host recovery after lethal infection indicates that these CTL
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Why do T-cells behave like prostitutes? #MSBlog #MSResearch #ResearchSpeak. As you know I think EBV causes MS, i.e. I think it is the pivotal factor in the causal pathway that leads to the onset of the disease. Studies have consistently shown that the immune response to EBNA-1 (EBV associated nuclear antigen-1) is increased in people at risk of MS and/or who have MS. Please note the use of and/or, because most people develop biological disease, i.e. MS, before their first symptoms. EBNA-1 is a so called latency programme antigen and keeps the EBV genome in hibernation. Some feel EBNA-1 is a molecular mimic and triggers cross-reactive immune responses to self-proteins. This is one of the main EBV hypotheses. Another hypothesis is that EBV infects cells within the brain and spinal cord and hence stimulates immune responses, by up-regulating innate immune mechanisms, or danger signals. If EBV does infect the central nervous system you would expect the nervous system to be enriched for T-cells ...
To assess herd immunity to swine influenza viruses, we determined antibodies in 28 paired serum samples from participants in a prospective serologic cohort study in Hong Kong who had seroconverted to pandemic (H1N1) 2009 virus. Results indicated that infection with pandemic (H1N1) 2009 broadens cross-reactive immunity to other recent subtype H1 swine viruses ...
Effect Diluent™ for dilution of bio samples, to avoid Hook Effects, reduce matrix effects and ensure that the signal response is within the standard curve.
1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content.. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin systems, but differs markedly for the cross reaction between egg albumin and antidye.. 3. A possible explanation for the occurrence of this one-sided crossreaction is given in terms of reactive groupings on the antigen and antibody.. 4. A qualitative expression of the course of the cross-reaction is given in terms of the laws of classical chemistry.. ...
Heterosubtypic T cell-mediated immunity to influenza A viruses in humans has been widely reported (24-26, 36). While cross-reactive T cells cannot prevent establishment of infection, they can enhance recovery by promoting virus clearance and reduce the severity of illness (15). It has also been demonstrated that in vitro T cell cultures derived from healthy individuals can lyse target cells infected with swine or avian influenza viruses (28, 29). Together with a large number of studies in mice that demonstrated cross-protection conferred by influenza A-specific T cells during subsequent challenges (reviewed in ref. 11), these studies suggest that vaccines stimulating cross-reactive T cell populations, potentially used in conjunction with the current antibody-based strategy, may confer broader and more effective protection against a potential pandemic strain. However, most studies using T cell cultures expanded in vitro were unable to assess accurately the overall influenza-specific memory T cell ...
Control of swine influenza by vaccination has become more difficult in recent decades, as the evolution of the virus has resulted in inconsistent responses to traditional vaccines. Standard commercial swine flu vaccines are effective in controlling the infection when the virus strains match enough to have significant cross-protection, and custom (autogenous) vaccines made from the specific viruses isolated are created and used in the more difficult cases.[80][81] Present vaccination strategies for SIV control and prevention in swine farms typically include the use of one of several bivalent SIV vaccines commercially available in the United States. Of the 97 recent H3N2 isolates examined, only 41 isolates had strong serologic cross-reactions with antiserum to three commercial SIV vaccines. Since the protective ability of influenza vaccines depends primarily on the closeness of the match between the vaccine virus and the epidemic virus, the presence of nonreactive H3N2 SIV variants suggests that ...
Self-reactive CD4 T cells are thought to have a central role in the pathogenesis of many chronic inflammatory human diseases. Microbial peptides can activate self-reactive T cells, but the structural basis for such crossreactivity is not well understood. The Hy.1B11 T cell receptor (TCR) originates from a patient with multiple sclerosis and recognizes the self-antigen myelin basic protein. Here we report the structural mechanism of TCR crossreactivity with two distinct peptides from human pathogens. The structures show that a single TCR residue (CDR3α F95) makes the majority of contacts with the self-peptide and both microbial peptides (66.7-80.6%) due to a highly tilted TCR-binding topology on the peptide-MHC surface. Further, a neighbouring residue located on the same TCR loop (CDR3α E98) forms an energetically critical interaction with the MHC molecule. These data show how binding by a self-reactive TCR favors crossreactivity between self and microbial antigens.
Full FDA Tissue Panel of high quality normal tissues for antibody cross-reactivity studies. Multiple organs from a range of age and gender-specific donors.
Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme that catalyzes the posttranslational modification of glutamine residues on protein or peptide substrates. 3-bromo-4 5 (DHI) scaffold have been widely used to study TG2 biology and are well tolerated in vivo but these compounds have only modest potency and their selectivity toward other transglutaminase homologues is largely unknown. In the present work we first profiled the selectivity of existing inhibitors against the most pertinent TG isoforms (TG1 TG3 and FXIIIa). Significant cross-reactivity of these small molecules with TG1 was observed. Structure-activity and ?selectivity analyses led to the identification of modifications that improved potency and isoform selectivity. Preliminary pharmacokinetic analysis of the most promising analogues was also undertaken. Our new data provides a clear basis for the rational selection of dihydroisoxazole inhibitors as tools for in vivo biological investigation. Kitl Introduction The mammalian ...
TY - JOUR. T1 - Epidemics in Competition. T2 - Partial Cross-Immunity. AU - Andreasen, Viggo. PY - 2018. Y1 - 2018. N2 - The competition between two pathogen strains during the course of an epidemic represents a fundamental step in the early evolution of emerging diseases as well as in the antigenic drift process of influenza. The outcome of the competition, however, depends not only on the epidemic properties of the two strains but also on the timing and size of the introduction, characteristics that are poorly captured by deterministic mean-field epidemic models. We describe those aspects of the competition that can be determined from the mean-field models giving the range of possible final sizes of susceptible hosts and cumulated attack rates that could be observed after an epidemic with two cross-reacting strains. In the limit where the size of the initial infection goes to zero, the possible outcomes lie on a (one dimensional) curve in the outcome space.. AB - The competition between two ...
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Interleukin-5 (IL-5) is a hematopoietic growth factor expressed in Th2, mast cells and eosinophils. IL-5 acts through its receptor, the IL-5 receptor (IL-5R) and is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be and is regulated by GATA-3, in addition to other transcription factors. Human and mouse IL-5 are cross-reactive. Recombinant mouse IL-5 is a non-glycosylated, disulfide-linked homodimer. It is comprised of two 113 amino acid chains with a total molecular weight of 26.2 kDa. Ships ambient. Store frozen at -20 to -10C. ...
A gray area at times. Have used the Scytek kit (check out website) for frozen sections, but did not use their peroxidase blocker, it ate frozens off the slide. Substituted a Dako peroxidase blocker for frozens was much friendlier. The kicker with this kit, their special blocker is excellent, and you have to use their chromogen with this kit. What really worked for us was to use their two blockers (not the peroxidase block though),a biotinylated primary in place of a secondary antibody with the Scytek kit since we did not have a purified primary on hand. We also diluted out the biotinylated primary further, so do a more extended dilution panel, this reduced our cross reaction background. This is the basis of the DAKO ARK kit, biotinylating the primary, some antibodies don biotinylate as well, a potential problem, but may work with yours, so another option - DAKO ARK kit. There are others on the market, Zymed, Innovex, Vector MOM kit, etc, all worth a try. Have heard some mixed reviews on Mouse ...
Species: Mouse Monoclonal Clone: 1A4 Isotype: IgG2a,k Species Reactivity: Human, Baboon, Cow, Rabbit, Mouse, Rat, Chicken. Positive Control: Blood vessels Specificity: This antibody recognizes the a-smooth muscle form of actin. It shows no cross reaction with actin from fibroblasts (b- and g-cytoplasmic), striated muscle (a-sarcometric), and myocardium (a-myocardial). Its epitope is composed of the acetyl group and the first 4 amino acids on the N-terminal end of the peptidic chain of a-smooth actin. ScyTek s 1A4 stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained as they also contain this actin ...
Species: Mouse Monoclonal Clone: 1A4 Isotype: IgG2a,k Species Reactivity: Human, Baboon, Cow, Rabbit, Mouse, Rat, Chicken. Positive Control: Blood vessels Specificity: This antibody recognizes the a-smooth muscle form of actin. It shows no cross reaction with actin from fibroblasts (b- and g-cytoplasmic), striated muscle (a-sarcometric), and myocardium (a-myocardial). Its epitope is composed of the acetyl group and the first 4 amino acids on the N-terminal end of the peptidic chain of a-smooth actin. ScyTek s 1A4 stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained as they also contain this actin ...
Although Ag-Ab reactions are highly specific, in some cases antibody elicited by one antigen can cross-react with an unrelated antigen. Such cross-reactivity
Hello, I work with fish in a resarch lab and with some of the antibodies I use I get what I would consider non-specific crossreactivity with mucus either covering the body surface or in mucocyte granules. More often this problem would arise with rabbit polyclonal anti-peptide antibodies using neat serum. I usually get around this by affinity purifying using the peptide but in some cases this is not possible. Someone once told me that mucoproteins have a large number of antigenic determinants increasing the likelyhood of crossreactivity but I could never find a reference. Ive searched through the archives but couldnt find an explanation except for a suggestion that it might be charge related. Could someone please shed some light on this situation for me. It is something that has bugged me for the longest time. Thank you for any insight. Sincerely, Jon _______________________________________________ Histonet mailing list [email protected] ...
Publications 164 Publications PUBLICATIONS 1. Heemskerk B, Veltrop-Duits LA, van Vreeswijk T, ten Dam MM, Heidt S, Toes RE, van Tol MJ, Schilham MW. Extensive cross-reactivity of CD4 + adenovirus-specific
Generate antibody (IgG) conjugates for immunocytochemistry (ICC), immunohistochemistry (IHC), flow cytometry, and cell imaging with the Invitrogen Zenon Rabbit IgG Labeling Kits. Simplify your laboratory applications and reduce antibody cross-reactivity while also achieving efficient labeling of ant
Biomarker studies which were previously limited by poor assay sensitivity, low throughput systems and insufficient sample amount are now feasible in a simple and efficient way.. For the first time it is possible to do high capacity quantification of 92 protein biomarkers in 96 samples. Conventional immunoassays have been unable to scale due to increasing antibody cross-reactivity but TATAA Biocenter offers a solution using the Multiplex platform from Olink Proteomics. It generates high quality data even in highly multiplexed formats and the opportunities are enormous for powerful analysis of multivariate biomarker patterns.. ...
Supplier: Assaypro • Crossreactivity: Bo, Ms, Rt, Pg, Mk, Dg, Rb • Format: Sandwich ELISA • Range: 3.125-200 ng/mL • Min. Sample Size: 50 uL • Sample Types: U, M, Sv, ...
In this thesis the role of bacteria for the induction of autoimmunity was investigated. In detail, it was examined whether bacteria are able to activate autoreactive CD4+-T-cells antigen-specific (cross-reactivity) or antigen-unspecific (bystander-activation). It was shown that the examined transgenic MBP-peptide specific T-cell-receptor recognized many natural occurring cross-reactive peptides of microbial origin, which induced an activation of the T-cells in vitro and which could induce autoimmune encephalomyelitis (EAE) in the T-cell-receptor transgenic mice in vivo. Furthermore, it was examined, whether lipopolysaccharide (LPS) as activator of the innate immune system could induce an unspecific activation of the autoreactive T-cells in vitro and whether administration of LPS in the transgenic mice could induce EAE in vivo. It was shown that LPS activates a small percentage of CD4+ - T-cells. Application of LPS to the transgenic T+alpha- mice induced EAE. Therefore, the role of ...
Despite inheriting half of its genetic material from its father, the fetoplacental unit is not rejected by the maternal immune system because of a unique immunological relationship with the mother
FOR BULK ORDER REQUESTS PLEASE CONTACT US Description :Rabbit Polyclonal Antibody Species : Tag : Expression System: Sequence : Specificity :Recognizes the PTK7 protein Cited Applications :WB, ELISA, IF, IHC Cross Reactivity :Human, Mouse and Rat Host / Isotype / Clone# :Rabbit, IgG Immunogen :PTK7 antibody was raised
The properties of high affinity and specificity of antibodies are successfully employed in assays used for quantification of specific analytes in complex mixtures. The method is indirect in the sense that it is the antibody-analyte complex that is detected rather than the analyte per se. However, if the quality of the antibody is good, i.e., low cross reactivity with other molecules, there is a strong relationship between the measured signal from the complex and the concentration of the analyte. This relationship can be determined by the use of calibrators with known concentrations, which allow for a standard curve to be constructed and the concentration in a sample to be calculated.. ...
anti-PTEN, mAb (16F3) is a monoclonal antibody that crossreacts with human, mouse, rat protein. Works in ELISA, WB. Important for Inflammation, Oxidative Stress, ROS, Immunology research.
anti-DJ-1 (PARK7), mAb (1D7) is a monoclonal antibody that crossreacts with human, mouse, rat protein. Works in ELISA, WB. Important for Inflammation, Oxidative Stress, ROS, Immunology research.
Citoxlab provides GLP-compliant Tissue Cross-Reactivity (TCR) studies for biologicals and monoclonals with all the tissues recommended by the FDA and EMEA.
, Rat Serum - 50mL, GTX73216, Applications: Blocking, ELISA, ICC/IF, IHC, WB; Blocking, ELISA, Immunocytochemistry/ Immunofluorescence (ICC/IF), Immunohistochemistry (IHC), Western Blot (WB); CrossReactivity:
, Human Brain: Amygdala (Normal) tissue lysate, GTX28766, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot (WB); CrossReactivity:
Newcombe, J, Eales-Reynolds, L, Wootton, L, Gorringe, AR, Funnell, SGP, Taylor, SC and McFadden, JJ (2004) Infection with an avirulent phoP mutant of Neisseria meningitidis confers broad cross-reactive immunity ...
Three anti-horse liver alcohol dehydrogenase (HLADH) monoclonal antibodies are described. Two are specific for ADH and cross-react with class I and II enzymes from mouse, horse and Chinese hamster....
TY - JOUR. T1 - Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers. AU - Chou, Ai Hsiang. AU - Liu, Chia Chyi. AU - Chang, Jui Yuan. AU - Jiang, Renee. AU - Hsieh, Yi Chin. AU - Tsao, Amanda. AU - Wu, Chien Long. AU - Huang, Ju Lan. AU - Fung, Chang Phone. AU - Hsieh, Szu Min. AU - Wang, Ya Fang. AU - Wang, Jen Ren. AU - Hu, Mei Hua. AU - Chiang, Jen Ron. AU - Su, Ih Jen. AU - Chong, Pele Choi Sing. PY - 2013/11/21. Y1 - 2013/11/21. N2 - Background: Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open-label phase I clinical study registered with #NCT01268787, aims to evaluate the safety, reactogenicity and immunogenicity of a formalin-inactivated EV71 vaccine candidate (EV71vac) at 5- and 10-μg doses. In this study we report the cross-neutralizing antibody responses from each ...
In a subset of patients with limited cutaneous (lc) systemic sclerosis (SSc), anti-CENP-A antibodies (Ab) cross-react with a peptide (FOXE3p53-62) that presents striking homology with one of the two immunodominant epitopes of CENP-A (Ap17-30). We searched for clinical correlates of anti-FOXE3p53-62 Ab by measuring their levels along with those of Ab to Ap17-30 and to the second immunodominant epitope of CENP-A, namely Ap1-17. Serum samples were obtained from 121 patients with SSc, 46 patients with systemic lupus erythematosus (SLE) and 25 healthy blood donors (HBD). The reactivity of serum IgG to Ap1-17, Ap17-30 and FOXE3p53-62 was measured by ELISA. The corresponding anti-peptide Ab were affinity-purified from pooled SSc sera and used to establish standard curves for quantifying these Ab in patients and HBD. Receiver operating characteristics (ROC) analysis, comparing SSc patients who were positive for anti-CENP Ab (ACA+) to those who were negative, was used to find cut-off points for dichotomizing the
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This thesis describes the investigation of the characteristics of cultured MSC with a special focus on the MSCs with in vivo bone forming capacity. The most relevant contributions of the work described in this thesis to the field of regenerative medicine, and bone tissue engineering research field in particular, are ... read more the following: 1) The identification of novel cross-reacting monoclonal antibodies for prospective isolation of primary MSCs (with clonogenic potential) from multiple mammalian species that are widely used in regenerative medicine research; 2)We investigated the use of human platelet lysate (PL) for MSC expansion as a substitute for fetal bovine serum (FBS). Use of PL enables MSCs expansion under GMP conditions in a relatively short time period, retaining a common phenotype and multipotency. This procedure is relevant for clinical applications that require high numbers of MSCs, such as in the treatment for graft-versus-host disease, Crohns disease, and rheumatoid ...
Abbkine Scientific has announced the launch of its new kit, the EliKine™ Human IL-2 ELISA Kit otherwise known as Human IL2 ELISA Kit. The launch of the product reiterates the companys commitment to enhancing research and investigation in the field of life science.. The product has a human reactivity, employing a two-site sandwich ELISA to quantitate IL-2 in samples. With colorimetric detection method and assay duration with multiple steps standard sandwich ELISA assay with a working time of 3-5 hours, the kit stands tall amongst its peers on the market.. The featured kit includes Human IL-2 microplate, Human IL-2 standard, Human IL-2 detect antibody, EliKine™ Streptavidin-HRP, Standard diluent, Assay buffer, HRP substrate, Stop solution, Wash buffer and Plate covers.. The major feature and benefit of the kit besides having a calibration range of 3.9 pg/ml-250 pg/ml is its high sensitivity and excellent specificity for detection of Human IL-2. It also has no significant cross-reactivity or ...
Human TNF-α ELISA Kit is the latest product from Abbkine Scientific Research Company. As part of the companys plans to ease the research process and ensure that better results are gotten in record time, the company made the announcement to official launch the Human TNF alpha ELISA Kit on the market.. The ELISA Kit is particularly designed to allow for the easy detection of Human TNF-α. Consequently, investigators, researchers and other such users of the product can easily get their desired results in record time. This also ensures that better results are gotten.. EliKine™ Human TNF-α ELISA Kit employs a two-site sandwich ELISA to quantitate TNF-α in samples, it has high sensitivity and excellent specificity for detection of Human TNF-α. No significant cross-reactivity or interference between Human TNF-α and analogues was observed.. The recent launch of the Human TNF-α ELISA Kit has been described by many as a revolutionary introduction to the industry. With a high sensitivity and ...
Objectives. This study tested the hypothesis, first proposed by Chaussinand, that individual-level immunity acquired from exposure to tuberculosis may have contributed to the disappearance of leprosy from western Europe. Methods. The epidemiological consequences of cross-immunity were assessed by the formulation of a mathematical model of the...
|strong|Mouse anti Human hCG anibody, clone INN-hCG-72|/strong| recognises exclusively free hCG alpha. It reacts with the alpha 6 epitope on hCG alpha. No cross reaction is observed with holo-hCG in d…
Swine flu has been in the headlines for days now. The headlines change every day. By the time this article is printed, the situation will have changed even more. Therefore, it is hard to write a timely article on this particular disease. There are some facts that bear no relation to time. The first is that we have flu epidemics every year. They usually occur in the December to February time frame. We start an immunization program for it prior to that. The viruses contained in the immunization are scientists best guesses as to which flu viruses are going to be prevalent that particular year. They usually guess correctly so many people are protected before each years outbreak. One of the issues with swine flu is that there is currently no immunization for it. Cross reaction to other flu strains is not present. Therefore, no one is immune to the virus. For that reason many more people would be affected by an outbreak. The second fact is that every year people who get the flu die from its ...
Centralized (ancestral and consensus) HIV-1 envelope immunogens induce broadly cross-reactive T cell responses in laboratory animals; however, their potential to elicit cross-reactive neutralizing antibodies has not been fully explored. Here, we report the construction of a panel of consensus subtype B (ConB) envelopes and compare their biologic, antigenic, and immunogenic properties to those of two wild-type Env controls from individuals with early and acute HIV-1 infection. Glycoprotein expressed from full-length (gp160), uncleaved (gp160-UNC), truncated (gp145), and N-linked glycosylation site deleted (gp160-201N/S) versions of the ConB env gene were packaged into virions and, except for the fusion defective gp160-UNC, mediated infection via the CCR5 co-receptor. Pseudovirions containing ConB Envs were sensitive to neutralization by patient plasma and monoclonal antibodies, indicating the preservation of neutralizing epitopes found in contemporary subtype B viruses. When used as DNA vaccines ...
An agglutination test used in the laboratory to diagnose rickettsial diseases. It depends on a nonspecific cross reaction between antibodies produced by the rickettsial infection with the OX-2, OX-19 and OXK antigens of the Gram negative rod, Proteus.. ...
The participants, recruited by advertisements in two daily newspapers, were obese and asthmatic. Inclusion criteria were ability to cope with the study protocol, body mass index 30-42, age 18-60 years, previously diagnosed asthma with a spontaneous diurnal variation or a bronchodilator response of 15% or more, and being a non-smoker or having stopped smoking for two years or more before age 50. Exclusion criteria were pregnancy, history of bulimia or anorexia, unstable angina or arrhythmia, untreated thyroid disease, symptomatic liver or gall bladder disorder, any other severe disease, insulin treatment, systemic steroid treatment, or history of food allergy or of intolerance to any component of the very low energy dietary preparation that would be used in the study-such as soya, fish, chocolate, or lactose. Participants with a history of adverse reactions to peas, beans, or peanuts were excluded because of possible cross reactions to soya protein.3. Telephone interviews were held with 202 ...
Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Killian on positive skin tb test: There is no cross reaction between them. By the way, up to 5% of normal individuals may test positive to ANA test, usually at low titer. for topic: Positive Skin Tb Test
I am a bioengineer fascinated by T cell immunology, and I have expertise in single-molecule mechanical analysis, single-molecule imaging, quantum dot nanotechno...
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.. 0 Comments. ...
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.. 0 Comments. ...
A new paper has just appeared in PLoS Medicine on an old topic: whether seasonal influenza vaccines might also cause enough cross-reactivity to protect against H5N1. The basic idea is simple. The immune system sees the surface proteins on the flu virus and makes protective antibodies against them. The major stimulant for this is the hemagglutinin protein (HA), the H part of H5N1. There are 16 different immunological flavors of HA that cross-react very little.
Hi, I have a mouse anti-bovine glutamate dehydrogenase mAb and Im curious whether anyone would know whether it will crossreact with Human GDH. I think the two proteins are fairly similiar but how similiar are humans with cows??? Please send a reply to my E-mail dsho at Thanx for any thoughts. Moo Moo, Dave Shock ...
Homo sapiens membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) (MCP), transcript variant h, mRNA. (H00004179-R27) - Products - Abnova
Homo sapiens membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) (MCP), transcript variant n, mRNA. (H00004179-R17) - Products - Abnova
We would like to thank Dr. Sylvain Lesne for his interest in our work and for his comments. We would like to clarify some of the points he raised concerning our report, since we disagree with some of his statements.. Regarding Aβ detection, we used the 6E10 antibody to monitor the level of APP transgene expression at the age we performed our analysis of spine density in vivo (i.e., three months postnatal), but our intention was not to characterize the presence of Aβ1-42 oligomers at this age in this mouse strain. They have been extensively characterized previously by others (see below). The 6E10 antibody is known to recognize human APP, CTF-β, and Aβ. We acknowledge that the band running below 15 kDa should be considered as a mixture of CTF/Aβ since tissues were homogenized in RIPA buffer. Regarding the APP signal at ~100 kDa, we could clearly detect a faint signal in the wild-type mice (after overexposure of the membrane), suggesting that the antibody can cross-react with mouse APP. This ...
FOR BULK ORDER REQUESTS PLEASE CONTACT US Description :Mouse Monoclonal Antibody Species : Tag : Expression System: Sequence : Specificity :Recognizes the p21CIP1 (p21/WAF1) protein Cited Applications : WB, ELISA, IP Cross Reactivity :Human Host / Isotype / Clone# :Mouse, IgG Immunogen :Produced by repeated immunizatio
Browse Item # 73-364, LRRTM2 in the Antibodies, Inc. catalog including Item #,Item Name,Description,Target,Applications,Clone,IgG Isotype,Species Reactivity,Validation,Type,Format,Cross Reactivity,Expected Banding Pattern,Host,Label,Antibody Type,Com
Browse Item # 73-136, GABA(A)R, Alpha1 in the Antibodies, Inc. catalog including Item #,Item Name,Description,Target,Applications,Clone,IgG Isotype,Species Reactivity,Validation,Type,Format,Cross Reactivity,Expected Banding Pattern,Host,Label,Antibod
Anne Schuchat: I think one possibility is that older people might have been exposed to H1N1 strains a long time ago that might have some relation to the strain were seeing now. Our virologists have compared it to all these other strains and this is really different. This is not a close, genetic relative of any of the H1N1s that have been a problem in people, but the immunologic characteristics might be different than the genetic characteristics and so it would be very great if older people had been exposed to some H1N1 a long time ago that had some relationship with this one immunologically and that might lead to that pre-existing immune they we hope is there, but were not sure is there. So we dont have a particular virus that were thinking about because the genetic characteristics are so different, but we are wondering about whether there were some viruses around back in the 30s, 40s or 50s that might be immunologically similar to the one were seeing now ...
Preamble: Stanford points out that the average 70-year-old is on 7 (seven) pharmaceutical agents1. Since literally hundreds of potential adverse reactions can occur with each medication, imagine the potential for cross reactivity (same reference quotes an average number of potential side effects per drug to be 69)…especially if a drugs metabolite can impart adverse reactions too?
Cross-reaction toxicity[edit]. Supplemental zinc can prevent iron absorption, leading to iron deficiency and possible ...
"Cross-Coupling Reactions". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rd100.pub2. Ljungdahl, Thomas ... "Two Competing Mechanisms for the Copper-Free Sonogashira Cross-Coupling Reaction". Organometallics. 27 (11): 2490-2498. doi: ... in an effective catalyst for coupling reactions such as the Kumada coupling and Suzuki reactions (example below). It also ... Kumada, Makota; Tamao, Kohei; Sumitani, Koji (1978). "Phosphine-Nickel Complex Catalyzed Cross-Coupling of Grignard Reagents ...
Cross-coupling reactions. Iron compounds such as Fe(acac)3 catalyze a wide range of cross-coupling reactions with one substrate ... In a complementary reaction, Collman's reagent can be used to convert acyl chlorides to aldehydes. Similar reactions can be ... including Friedel-Crafts reactions and lithation. Some electrophilic functionalization reactions, however, proceed via initial ... Complexes of the type Fe2(SR)2(CO)6 and Fe2(PR2)2(CO)6 form, usually by the reaction of thiols and secondary phosphines with ...
These enzymes are capable of carry out reaction even in the absence of the protein-based active site organization or carry out ... X. Cross-association of Tert Butyllithium. Kinetics of Tert Butyllithium Dissociation". Journal of the American Chemical ... The ligands can act as a catalyst to carry out different reactions, depending on which transition metal being at the center. ... Using mass spectroscopy, the existence of cross-association with other organolithium species in the vapor phase could also be ...
Oxidative Cross‐Coupling Reactions. Aiwen Lei, Wei Shi, Chao Liu, Wei Liu, Hua Zhang, Chuan He, Wiley‐VCH Verlag GmbH & Co. ... Usually oxidative couplings are catalysed by a transition metal complex like in classical cross-coupling reactions, although ... Another reaction is the synthesis of 1,1'-Bi-2-naphthol from 2-naphthol by iron chloride, discovered in 1873 by Alexander ... Early examples involve coupling of terminal alkynes: 2 RC≡CH + 2 Cu(I) → RC≡C-C≡CR + 2 Cu + 2 H+ Coupling reactions involving ...
Reaction mechanism[edit]. The reaction mechanism is thought to proceed via a standard Pd catalyzed cross-coupling pathway, ... The Negishi coupling is a widely employed transition metal catalyzed cross-coupling reaction. The reaction couples organic ... Sase, S.; Jaric, M.; Metzger, A.; Malakhov, V.; Knochel, P. (2008). "One-Pot Negishi Cross-Coupling Reactions of In Situ ... Nicolaou, K. C.; Bulger, P. G.; Sarlah, D. (2005). "Palladium-catalyzed cross-coupling reactions in total synthesis". Angew. ...
... the Kumada coupling is a type of cross coupling reaction, useful for generating carbon-carbon bonds by the reaction of a ... Heck reaction Hiyama coupling Suzuki reaction Negishi coupling Petasis reaction Stille reaction Sonogashira coupling Corriu, R ... The reaction is notable for being among the first reported catalytic cross-coupling methods. Despite the subsequent development ... Frisch, Anja C.; Beller, Matthias (21 January 2005). "Catalysts for Cross-Coupling Reactions with Non-activated Alkyl Halides ...
Many decades later, interest in base metal catalysis sparked significant efforts to further develop cross-coupling reactions ... Fürstner, Alois; Leitner, Andreas; Méndez, María; Krause, Helga (2002-11-01). "Iron-Catalyzed Cross-Coupling Reactions". ... He developed the Kochi reaction, a variation on the Hunsdiecker reaction. Kochi was of Japanese descent and he and his family ... Kochi's work showed that this reaction proceeds via a complex between benzene (the donor) and nitrosonium ion (the acceptor). ...
"A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly ... The Suzuki-Miyaura and Negishi cross-coupling reactions were typically performed with Pd(PPh3)4 as catalyst and were mostly ... Bruno, N. C.; Buchwald, S. L. (2014). Palladium Precatalysts for Cross-Coupling Reactions (PDF). The Strem Chemiker. Surry, ... Martin, Ruben; Buchwald, Stephen L. (18 November 2008). "Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing ...
Hypersensitivity cross-reactions with penicillins are rare. Ertapenem also can have an effect on some blood tests such as liver ... or with severe hypersensitivity reactions (such as anaphylaxis or severe skin reactions) to other beta-lactam antibiotics in ... It inhibits cross-linking of the peptidoglycan layer of bacterial cell walls by blocking a type of enzymes called penicillin- ... Common side effects are diarrhoea (in 5% of people receiving ertapenem), nausea (in 3%) and vomiting, reactions at the ...
88, 860 (1952). Cross Sections for Nuclear Reactions Involving Nuclear Isomers. Bruno Linder* and Ralph A. James. Department of ... Vol 93, Number 2, p. 288-290 Proton Induced Reactions of Thorium-Fission Yield Curves. Howard A. Tewes and Ralph A. James. ... 85, 369 (1952). Excitation Functions of Proton-Induced Reactions of Nb93. Ralph A. James. Physical Review - January 1954. ...
These reactions are examples of cross-coupling reactions. Ullmann-type reactions are comparable to Buchwald-Hartwig reactions ... The corresponding Goldberg reaction, is named after Irma Goldberg. The Hurtley reaction, which involves C-C bond formation, is ... In the case of Ullmann-type reactions (aminations, etherifications, etc. of aryl halides), the reaction involves copper(I) ... As this reaction proceeds well with an electron-rich aryl iodide it is a valuable alternative to the Buchwald-Hartwig amination ...
世界の化学者データベース「鈴木章」 Miyaura, Norio; Suzuki, Akira (1995). "Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds ... "A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides ... who first published the Suzuki reaction, the organic reaction of an aryl- or vinyl-boronic acid with an aryl- or vinyl-halide ... The postdoctoral experience was utilized in the study of the coupling reaction with his assistant Norio Miyaura and led to the ...
These products are useful for cross-coupling reactions. (9) Zirconium-catalyzed carboalumination of alkynes by trimethylalane ... Workup of these reactions should employ extreme pH's (10% hydrochloric acid or 6 N sodium hydroxide), as moderate pH encourages ... Reactions of alkenyl- and alkynylaluminium compounds involve the transfer of a nucleophilic alkenyl or alkynyl group attached ... House, H. O. Modern Synthetic Reactions, 2nd ed., Benjamin/Cummings, Menlo Park, CA, 1972. Eisch, J. J.; Kaska, W. C. J. Am. ...
doi:10.1016/S0040-4039(00)60957-7. Miyaura, Norio; Suzuki, Akira (1995). "Palladium-Catalyzed Cross-Coupling Reactions of ... 2005). Name Reactions and Reagents in Organic Synthesis (2nd ed.). ISBN 978-0471228547. Comins, Daniel L.; Dehghani, Ali (1992 ... The vinyl triflates prepared are useful as substrates in the Suzuki reaction. Bis(trifluoromethanesulfonyl)aniline Mundy, ...
It is typically achieved by cross-coupling reactions. The most basic aryl group is phenyl, which is made up of a benzene ring ...
These versatile intermediates can then be used for a wide range of chemical transformations such as cross-coupling reactions, ... The reaction is mechanistically related to the Tebbe reaction and can be catalyzed by various Lewis acids (e.g. TiCl4 or Al2Me6 ... This powerful carbon-carbon bond forming cross-coupling reactions combines an organic halide and an organozinc halide reagent ... This group transfer reaction can be used in allylation, or other coupling reactions (such as Negishi coupling). One of the ...
"Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds". Chemical Reviews. 95 (7): 2457-2483. CiteSeerX 10.1. ... This reaction type is exemplified in the Suzuki reaction, which involves coupling of aryl- or vinyl-boronic acid with an aryl- ... Displayed is a reaction sequence starting with reaction of allyl magnesium bromide with trimethyl borate, followed by ... Metal-catalyzed C-H Borylation reactions are transition metal catalyzed organic reactions that produce an organoboron compound ...
These hypersensitivity reactions to tetrazepam share no cross-reactivity with other benzodiazepines. Tetrazepam is used ... Barbaud, A; Girault, PY; Schmutz, JL; Weber-Muller, F; Trechot, P (July 2009). "No cross-reactions between tetrazepam and other ... Kämpgen, E; Bürger, T; Bröcker, EB; Klein, CE (November 1995). "Cross-reactive type IV hypersensitivity reactions to ... Allergic reactions to tetrazepam occasionally occur involving the skin. Allergic reactions can develop to tetrazepam and it is ...
Diederich, F.; de Meijere, A. (Eds.) "Metal-Catalyzed Cross-Coupling Reactions II", Wiley-VCH, Weinheim, 2004. Diederich, F.; ... Diederich, F.; Stang, P. J. (Eds.) "Metal-Catalyzed Cross-Coupling Reactions", Wiley-VCH, Weinheim, 1998. Diederich, F.; Stang ...
Other mango compounds potentially responsible for the dermatitis or allergic reactions include mangiferin. Cross-reactions may ... Oka K, Saito F, Yasuhara T, Sugimoto A (2004). "A study of cross-reactions between mango contact allergens and urushiol". ... Miell J, Papouchado M, Marshall A (1988). "Anaphylactic reaction after eating a mango". British Medical Journal. 297 (6664): ...
In an example of a present-day cross coupling reaction called decarboxylative coupling, a catalytic amount of Cu(I) displaces a ... Ullmann reaction involves copper-mediated reactions of aryl halides. Two types of Ullmann reaction are recognized: Classic ... Beletkaya, I.P.; Cheprakov, A.V. (2004). "Copper in Cross Coupling Reactions: The Post Ullman Chemistry". Coord. Chem. Rev. 248 ... Prior to the development of palladium-catalyzed cross coupling reactions, copper was the preferred catalyst for almost a ...
Cross-allergic reactions occur among the β-lactam antibiotics. To determine whether treatment with a β-lactam is safe when an ... Approximately five percent of patients have some kind of reaction, ranging from maculopapular rash (the most common rash seen ... which reacts with proteins and serves as a hapten to cause an immune reaction. ... allergy is noted, patient history regarding severity of previous reaction is essential. Ferrier, Denise R. (2011). Pharmacology ...
It is a cross-coupling reaction. This reaction was invented by and named after Jiri Srogl from the Academy of Sciences, Czech ... Cheng, Hong-Gang; Chen, Han; Liu, Yue; Zhou, Qianghui (March 2018). "The Liebeskind-Srogl Cross-Coupling Reaction and its ... The overall reaction scheme is shown below. Liebeskind-Srogl reaction is most commonly seen with thioether or thioester ... The Liebeskind-Srogl coupling reaction is an organic reaction forming a new carbon-carbon bond from a thioester and a boronic ...
D. Enders, O. Niemeier & T. Balensiefer (2006). "Asymmetric Intramolecular Crossed-Benzoin Reactions by N-Heterocyclic Carbene ... The reaction can be extended to aliphatic aldehydes with base catalysis in the presence of thiazolium salts; the reaction ... The reaction generally occurs between aromatic aldehydes or glyoxals. The reaction produces an acyloin. In the classic ... The catalytic version of the reaction involving cyanide was developed by Nikolay Zinin in the late 1830s, The reaction is ...
136Xe reaction. They failed to observe a single atom in such a reaction, putting the upper limit on the cross section, the ... In comparison, the reaction that resulted in hassium discovery, 208Pb + 58Fe, had a cross section of ~20 pb (more specifically ... For example, in the 28 14Si + 1 0n → 28 13Al + 1 1p reaction, cross section changes smoothly from 370 mb at 12.3 MeV to 160 mb ... Kern, B. D.; Thompson, W. E.; Ferguson, J. M. (1959). "Cross sections for some (n, p) and (n, α) reactions". Nuclear Physics. ...
Ethoxide in Suzuki Cross Coupling Reactions". Organic Letters. 2 (17): 2691-2694. doi:10.1021/ol0062446. ISSN 1523-7060. PMID ... reactions. A thallium stress test is a form of scintigraphy in which the amount of thallium in tissues correlates with tissue ... depending on the reaction under study, are reported for thallium, reflecting the greatly decreased stability of the +3 ...
Denmark, Scott E.; Smith, Russell C. (3 February 2010). "Mechanistic Duality in Palladium-Catalyzed Cross-Coupling Reactions of ... Ogawa, Akiya; Curran, Dennis P. (1997). "Benzotrifluoride: A Useful Alternative Solvent for Organic Reactions Currently ... and silylation reactions. The dielectric constants for dichloromethane and trifluorotoluene are 9.04 and 9.18, respectively, ... trifluorotoluene is useful in mild Lewis-acid catalyzed reactions, such as the Friedel-Crafts preparations. The most common ...
... s are also starting materials for certain cross-coupling reactions. In the first report on this reaction type the ... This reaction requires a strong base. If sodium methoxide is used as the base the reaction is called a Bamford-Stevens reaction ... In the Shapiro reaction tosylhydrazones are used as a leaving group in elimination reactions. ... New Uses for Classic Reagents in Palladium-Catalyzed Cross-Coupling and Metal-Free Reactions. Angewandte Chemie International ...
a b c Cross Currents. Labor unions in Japan. CULCON. Retrieved 11 June 2011 ... This produced a reaction which led to all the colonies restricting Chinese and other Asian immigration. This was the foundation ... Unions may organize a particular section of skilled workers (craft unionism),[3] a cross-section of workers from various trades ... Labor Notes is the largest circulation cross-union publication remaining in the United States. It reports news and analysis ...
... the mass of any one element at the beginning of a reaction will equal the mass of that element at the end of the reaction.[24]: ... This has led to the concept or area of study known as cross-boundary subsidy.[59][60] "This leads to anomalies, such as food ... These chemical reactions require energy, which mainly comes from the Sun and largely by photosynthesis, although a very small ... The components of food webs, including organisms and mineral nutrients, cross the thresholds of ecosystem boundaries. ...
Other important reactions include the formation of chlorite, glauconite, illite and iron oxide (if oxygenated pore water is ... Plane light above, cross-polarized light below. Scale box is 0.25 mm. ... Chemically speaking, increases in temperature can also cause chemical reaction rates to increase. This increases the solubility ...
In reaction to the relegation of the autochthonous language, a series of literary and historical works (always written in ... "Talking at cross-purposes? The missing link between feminist linguistics and translation studies". Gender and Language ...
Cross-sensitizationEdit. Cross-sensitization is a phenomenon in which sensitization to a stimulus is generalized to a related ... Tests that are commonly used place potential allergens on the skin of the patient and looking for a reaction to look for an ... In animals, cross-sensitization has been established between the consumption of many different types of drugs of abuse - in ... Similarly, reward sensitization to a particular addictive drug often results in reward cross-sensitization, which entails ...
Circumstances and Consequences of Cross-Species Transmission. Current Topics in Microbiology and Immunology. Ebolavirus and ... detecting the viral RNA by polymerase chain reaction (PCR)[6][23] and detecting proteins by enzyme-linked immunosorbent assay ( ... reactions to the 1976 Ebola outbreak in Zaire.[236][237] ...
Stevens's reaction was not to conduct experiments to test for the presence of additive structure in sensations, but instead to ... Cross-correlation (XCF). *ARMA model. *ARIMA model (Box-Jenkins). *Autoregressive conditional heteroskedasticity (ARCH) ... the operational theory of measurement was a reaction to the conclusions of a committee established in 1932 by the British ...
... you have to cross the cell membrane, just like if you were headed for the extracellular space. In those cases, chloroplast- ... its genes encode eleven subunits of a protein complex which mediates redox reactions to recycle electrons,[24] which is similar ...
Cross-refs to other MoS pages have been done as piped links to reduce verbiage. The cross-ref to WP:Naming conventions ( ... The reaction is either nothing, or WP:Thanks notices. Just recently: [1]. I don't think anyone bothers with this gnoming except ... I've better cross-referenced those (plus MOS:ICONS, MOS:IMAGES, MOS:FORMULAE, etc.) so this isn't just buried in one place no ... After the diacritics merge, cross-references can be used at MOS:BIO, etc., as needed, and the WP:DIACRITICS wording can also be ...
Originally calcitic crinoid stem (in cross-section) diagenetically replaced by marcasite in a siderite concretion; Lower ... Abercrombie, H. J.; Hutcheon, I. E.; Bloch, J. D.; Caritat, P. (1994). "Silica activity and the smectite-illite reaction". ...
Polymerase chain reaction (PCR) tests for Lyme disease have also been developed to detect the genetic material (DNA) of the ... ticks will tend not to cross it; acaricides may also be sprayed on it to kill ticks.[146] A sun-exposed tick-safe zone at least ... Chronic symptoms from an autoimmune reaction could explain why some symptoms persist even after the spirochetes have been ... The production of this reaction might be due to a form of molecular mimicry, where Borrelia avoids being killed by the immune ...
Cross KM, Kuenze C, Grindstaff TL, Hertel J (September 2011). "Thoracic spine thrust manipulation improves pain, range of ... Hurwitz EL, Morgenstern H, Vassilaki M, Chiang LM (July 2005). "Frequency and clinical predictors of adverse reactions to ... adverse reactions appear to be more common following manipulation than mobilization.[139] The most frequently stated adverse ...
When something is found, the rods cross over one another making an X over the found object. If the object is long and straight ... bodies absorbed the radio waves and unconscious hand movement reactions took place following the standing waves or intensity ...
Reaction with water On reaction with water, they generate hydroxide ions and hydrogen gas. This reaction is vigorous and highly ... and cross-section towards neutron absorption.[10]:74 ... Representative reactions of alkali metalsEdit. Reaction with ... Reaction 1) is known as Birch reduction. Other reductions[144] that can be carried by these solutions are: S8 + 2e− → S82-. Fe( ... Hagen, A. P. (17 September 2009). Inorganic Reactions and Methods, The Formation of Bonds to Group-I, -II, and -IIIB Elements. ...
A cross between a shedding breed and a poodle (which does not shed much) does not reliably produce a nonshedding dog. Traits of ... can trigger a reaction in a sensitive person. An air cleaner, air duct outlet and vacuuming with a vacuum cleaner with a HEPA ... Poodles are crossed with other breeds for various reasons, and the resulting puppies (called designer dogs) are described by ... The progenitor of the breed might have also been crossed with the Hungarian Puli.[14] The French name Caniche comes from the ...
Boubli, Lizzie (2003). "Michelangelo and Spain: on the Dissemination of his Draughtsmanship". Reactions to the Master edited by ... Christ on the Cross Adored by Two Donors. *Santo Domingo el Antiguo Altarpiece ...
Reaction time to situations where one must choose between two or more alternatives is one measure of control of processing. ... 15 Cross-paradigmatic. 12. Postformal. 7 16 Meta-paradigmatic. The theory of Andreas DemetriouEdit. The models above do not ... It is measured in reference to the reaction time to very simple tasks, such as the time needed to recognize an object. ...
Self-report survey methodology is the most used approach in OHP research.[37] Cross-sectional designs are commonly used; case- ... Fredrikson M., Sundin O., & Frankenhaeuser M. (1985). Cortisol excretion during the defence reaction in humans. Psychosomatic ... Johnson, J.V., & Hall, E.M. (1988). Job strain, workplace social support, and cardiovascular disease: A cross-sectional study ... Fredikson, Sundin, and Frankenhaeuser (1985) found that reactions to psychological stressors include increased activity in the ...
... landing cross-range and operational flexibility of reusable orbital spaceplane concepts being developed such as the Reaction ... ZrC has also been observed as a product from the reaction, but if the reaction is carried out with 20-25% excess B4C, the ZrC ... Stoichiometric reactions have also been carried out by reaction of attrition milled (wearing materials by grinding) Zr and B ... ZrO2 and HfO2 can be dispersed in boron carbide polymeric precursors prior to reaction. Heating the reaction mixture to 1500 °C ...
The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon-carbon bonds. It employs a ... Cu(I) is a co-catalyst in the reaction, and is used to increase the rate of the reaction. The Sonogashira reaction is typically ... It is an extension to the Cassar and Dieck and Heck reactions, which afford the same reaction products, but use harsh reaction ... Castro-Stephens coupling Heck reaction Stille reaction Suzuki reaction Negishi coupling Kumada coupling Transmetalation ...
Thank You that You died on the cross for me so that I could be forgiven and set free. Thank You that You offer me forgiveness ... Some affirm that it evolved, in some form or another, during the early days of the Protestant Reformation, as a reaction ... Thank You for dying on the cross for my sins. I open the door of my life and receive You as my Savior and Lord. Thank You for ... "What about the thief on the cross?". Retrieved 5 August 2019.. ...
These neutrinos emitted from this reaction are called solar neutrinos. Photons, created by the nuclear fusion in the center of ... A cross-section of the Super-Kamiokande detector.. Table 1 Phase. SK-I. SK-II. SK-III. SK-IV ... apparently in a chain reaction or cascading failure, as the shock wave from the concussion of each imploding tube cracked its ... and by adding protective acrylic shells that are hoped will prevent another chain reaction from recurring (Super-Kamiokande-II ...
A direct confirmation can be obtained by reverse transcription polymerase chain reaction, where the genome of the virus is ... Since these tests can cross-react with other flaviviruses, such as dengue virus, these indirect methods cannot conclusively ... blood-sample testing with polymerase chain reaction is required.[4] ...
... cross-dressers, and people who need sex reassignment" from driving.[43] ... were reluctant to be open with their identity for fear of negative reactions.[10] ...
... was started through concerts organized by the Australian Red Cross along with a Red Cross Music Therapy Committee. The key ... This category can be used when the focus of clinical attention is a reaction to the death of a loved one. As part of their ... However, the presence of certain symptoms that are not characteristic of a "normal" grief reaction may be helpful in ... Valentino, R. E. (2006). Attitudes towards cross-cultural empathy in music therapy. Music Therapy Perspectives, 24(2), 108-114. ...
"Instant Reaction" - Clarence Carter, Bruce Channel. *"Mr Busdriver" - Bruce Channel. *"Things Go Better With You" - The April ... "Sailing" - Christopher Cross (songwriter) (1981). *"Bette Davis Eyes" - Donna Weiss & Jackie DeShannon (songwriters) (1982) ...
It contains "obstinate samskaras, impressions, associations, fixed notions, habitual reactions formed by the past."[43] ... He recommends that the only way to reconcile the materialistic mind with the other truth would be to cross over the layers of ... as the result of evolution the mind has accustomed itself to depend upon certain physiological functioning and their reactions ...
"Arianism" in Cross, F.L. & Livingstone, E.A. (eds) The Oxford Dictionary of the Christian Church (1974) ... in reaction to Adoptionism, Sabellianism, and Arianism. Adoptionism was the belief that Jesus was an ordinary man, born of ... Cross, F.L. (1958). The Oxford Dictionary of the Christian Church. London: OUP, p. 81. ... or a cross-or on a crucifix, so that the Father is the only human figure shown at full size. In early medieval art, the Father ...
Grand Crosses of the Order of Saint James of the Sword. *Grand Crosses Special Class of the Order of Merit of the Federal ... Knights Grand Cross with Collar of the Order of Merit of the Italian Republic ... Grand Crosses of the Order of Aviz. * ... Reactions to the death. Work. *Royal Project Foundation. *Royal ... Grand Crosses of the Order of Christ (Portugal). * ... Knights Grand Cross of the Order of the Direkgunabhorn. *Order ...
of the reaction is unchanged, while the apparent affinity of the substrate to the binding site is decreased (the K. d. {\ ... MPTP is able to cross the blood brain barrier and enter acidic lysosomes.[13] MPTP is biologically activated by MAO-B, an ... Adding a competitive inhibitor to an enzymatic reaction increases the Km of the reaction, but the Vmax remains the same. ... Adding a competitive inhibitor to an enzymatic reaction increases the Km of the reaction, but the Vmax remains the same. ...
The traditional transition metal-catalyzed cross-coupling reaction, although well suited for C(sp2)-C(sp2) cross-coupling, has ... Ni and Fe-Based Cross Coupling Reactions Articles in Focus. Enjoy free access to selected articles from our recently completed ... Article 2: Fe-Catalyzed Cross-Dehydrogenative Coupling Reactions. by Leiyang Lv, Zhiping Li ... Cross-dehydrogenative coupling (CDC), which enables the formation of carbon-carbon (C-C) and C-heteroatom bonds from the direct ...
About the American Red Cross: The American Red Cross shelters, feeds and provides emotional support to victims of disasters; ... The Red Cross is a not-for-profit organization that depends on volunteers and the generosity of the American public to perform ... Its important to be prepared in case of a reaction, and were excited to offer this class to the community. This is a great ... "Its important to be prepared in case of a reaction, and were excited to offer this class to the community," said Kelly Hudson ...
The Suzuki-Miyaura reaction was first published in 1979 and is a non-toxic method of producing biaryls, alkenes and styrenes ... The chemistry of the Suzuki-Miyaura Cross-Coupling Reaction. The Suzuki-Miyaura reaction is best described as a catalytic cycle ... The Suzuki-Miyaura Cross-Coupling reaction was first published in 1979 by Akira Sazuki and Norio Miyaura. It is also known as ... The use of organoboron compounds as a reagent provides high selectivity and stability in cross-coupling reactions as well as ...
Cross-national evidence of a negativity bias in psychophysiological reactions to news. View ORCID ProfileStuart Soroka, Patrick ... Replication Data for: Cross-National Evidence of a Negativity Bias in Psychophysiological Reactions to News. Harvard Dataverse ... Cross-national evidence of a negativity bias in psychophysiological reactions to news ... Cross-national evidence of a negativity bias in psychophysiological reactions to news ...
The surprise is how many of the reactions crossed the usual political boundaries. ... A Breast-Feeding Plan Mixes Partisan Reactions. By KATE ZERNIKE. FEB. 17, 2011. ... A Breast-Feeding Plan Mixes Partisan Reactions. Order Reprints, Todays Paper,Subscribe ...
Negishi cross-coupling reactions of secondary alkyl zinc halides with aryl halides utilize PEPPSI™-IPent, boasting higher ... In Stille-Migita cross-couplings of heteroaryl stannanes with aryl halides, PEPPSI™-IPent allowed for lower reaction ... The PEPPSI™-IPent (732117) further advances the agility of cross-coupling reactions by being air-stable and thus increasing ... IPent is a highly effective catalyst in challenging Suzuki-Miyaura and Negishi cross-coupling reactions. This produces tetra- ...
... to set up and troubleshoot some of the most commonly used cross-coupling reactions throughout academia and industry.. The Cross ... Setting Up a Cross-Coupling Reaction. General Troubleshooting. Buchwald-Hartwig Amination:. Primary & Secondary Amines. ... Claim Your Complimentary Cross-Coupling Reaction Guide. Please provide the required (*) information below to your free copy of ... with the Cross-Coupling Guide. We are excited to introduce our new Cross-Coupling Guide to support practicing chemists like you ...
Cablegate: Media Reaction: Cross-Strait Charter Flights. Monday, 19 June 2006, 10:04 pm. Cable: Wikileaks. Ref: 06AITTAIPEI2099 ... SUBJECT: MEDIA REACTION: CROSS-STRAIT CHARTER FLIGHTS 1. Summary: Taiwans major Chinese-language dailies focused their ... cross-Strait charter flights. A "China Times" editorial said the cross-Strait charter flights can barely meet the Taiwan ... said the cross-Strait charter flights will only make the Taiwan people tilt even more toward China, while they do nothing to ...
Thomson Carbon Cross Bar - Lowest Prices and FREE shipping available from The World ... Thomson Carbon Cross Bar. Dynamically designed to help you slice through the air with as streamlined a form as possible, this ... Buy Thomson Components from Chain Reaction Cycles, the Worlds Largest Online Bike Store. ... this cross bar is a classy selection for the avid CX Racer. ...
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Idiotypic cross-reactions of monoclonal human lupus autoantibodies.. Y Shoenfeld, D A Isenberg, J Rauch, M P Madaio, B D ... Idiotypic cross-reactions of monoclonal human lupus autoantibodies.. Y Shoenfeld, D A Isenberg, J Rauch, M P Madaio, B D ... The idiotypic cross-reactions of immunoglobulins from unrelated patients suggest that the autoantibodies are derived from ... Idiotypic cross-reactions were evaluated in 60 polynucleotide-binding monoclonal lupus autoantibodies produced by human-human ...
CHICAGO -- Heres a quick look at the Chicago Blackhawks 4-3 triple-overtime win over the Boston Bruins in Game 1 of the Stanley Cup finals at the United Center on Wednesday.
Red Cross Tents At Yunnan Earthquake Site, Netizen Reactions. by Peter Barefoot Friday, September 14, 2012, 5:45 pm. 216 ... Those are not the Red Cross Societys tents. The Red Cross takes the money from donors, takes a percentage, and simply does ... What do you think? Of the Red Crosss work in this disaster? Of the netizen publics cynicism towards the Red Cross? ... The Red Cross Society cannot be forgiven, dont think you can put up a few tents and say youre doing good deeds. The money was ...
The neutron incident energy around 14-15 MeV is adequate to excite the nucleus for the reactions such as (n, p), (n,... ... n, α) cross section Nuclear reactions TALYS 1.9 nuclear model code EMPIRE 3.2 (Malta) nuclear model code ... Theoretical cross-sectional calculation of some structural fusion material on (n, α)-induced reactions. ... the reaction cross-sectional data have a critical importance in fusion reactors and development. Neutron irradiation produces ...
Cross-Reactions of Streptococcal Group-Specific Substances in Antipneumococcal Serums Message Subject. (Your Name) has ... Cross-Reactions of Streptococcal Group-Specific Substances in Antipneumococcal Serums. By Michael Heidelberger, Richard M. ... Cross-Reactions of Streptococcal Group-Specific Substances in Antipneumococcal Serums. By Michael Heidelberger, Richard M. ...
Sonogashira reaction turned out to be the most effective and convenient method to introduce functionalized alkynyl group into ... In this way the utility of such reactions to heterocyclic systems, which were neglected so far, could be figured out. Halogen ... The introduction of the desired side chains by Carbon-Carbon bond formation reactions was achieved by Sonogashira coupling and ... As a synthetic strategy, palladium-catalyzed coupling reactions were used to introduce side chains and aryl substituents into ...
Although this reaction is catalysed by Ni or Pd complexes, the latter have been much more developed. Nevertheless, Ni ... The Negishi cross-coupling of organozinc reagents is a valuable tool for the formation of C-C bonds in the presence of ... Negishi cross-coupling. reactions: scope and mechanisms V. B. Phapale and D. J. Cárdenas, Chem. Soc. Rev., 2009, 38, 1598 DOI: ... Negishi cross-coupling. of organozinc reagents is a valuable tool for the formation of C-C bonds in the presence of functional ...
A new approach towards reprocessing cross-linked rubbery materials by catalytic disassembly of polymer chains, which eliminates ... A facile route for rubber breakdown via cross metathesis reactions R. F. Smith, S. C. Boothroyd, R. L. Thompson and E. Khosravi ... This reaction can be achieved at room temperature within 2.5 h. Increasing the reaction time and temperature increased the ... networks at their double bonds via cross-metathesis (CM) reactions to produce readily soluble molecules. A dramatic reduction ...
... Author(s). McAvoy, Camille Z ... Furthermore, the products of this cross-coupling can be used for a subsequent electrocyclization through a reaction with ... A final C-N bond formation study focuses on the cross-coupling of aryl halides with amidine salts. For this cross-coupling, a ... Thus, methodologies for various palladium-catalyzed, C-N cross-couplings as well as a potential ligand synthesis to be used for ...
For others, the allergic reaction to an insect sting can be life-threatening. ... the reaction to a sting is brief, with redness and swelling followed by pain and itching. ... Sometimes this reaction can be life-threatening.. This severe reaction is a medical emergency that can happen very quickly. It ... The reaction is brief, with redness and swelling followed by pain and itching. Generally, the reaction lasts only a few hours, ...
Others may have an allergic reaction that is life-threatening. Read on for details. ... the reaction to a sting is brief, with redness and swelling followed by pain and itching. ... Sometimes this reaction can be life-threatening. This severe reaction is a medical emergency that can happen very quickly. It ... The reaction is brief, with localized redness and swelling followed by pain and itching. Generally, the reaction lasts only a ...
... and reduced cross sections [equation]allows the comparison of heavy-ion-induced reaction cross sections for a broad range of... ... Angular Distribution Excitation Function Reaction Cross Section Compound Nucleus Coulomb Barrier These keywords were added by ... Cross sections of α-induced reactions for targets with masses A ≈ 20-50 at low energies. ... Motivated by these unexpected discrepancies, the present study analyses \( \alpha\)-induced reaction cross sections for targets ...
And they know when being too noisy will get them a cross reaction from their parents. I thought I got what cross reaction ... Cross here means annoyed, slightly angry. The children know how to make their parents react in annoyance/anger. ... Oh I didnt know that the word cross has that kind of meaning. Thank you very much. Ive learned something new. ...
... Ian C. Stewart, Christopher J. Douglas and ... Steric bulk of N-heterocyclic carbene ligands affects the efficiency in cross-metathesis reactions. For the formation of ...
The Reductive Cross-Aldol Reaction. A reductive cross-aldol reaction was recently developed by the Baba group (Org. Lett. 2005 ... and the reductive cross-aldol reaction.. II. The Cross-Aldol reaction of aldehyde enolates with aldehydes. The work developed ... Asymmetric Cross-Aldol Reactions Of Aldehydes: A Formidable Synthetic Challenge. The aldol addition reaction is one of the most ... Chem. 1980, 45, 1066). The cross-aldol reaction between an aldehyde and an α,β-unsaturated aldehyde via titanium enolates was ...
Buy Metal Catalyzed Cross-Coupling Reactions and More: 3 Volume Set by From WHSmith today! FREE delivery to store or FREE UK ... Organosilicon Compounds in Cross-Coupling Reactions Cross-Coupling of Organyl Halides with Alkenes - The Heck Reaction Cross- ... Coupling Reactions to sp Carbon Atoms Carbometallation Reactions Palladium-Catalyzed 1,4-Additions to Conjugated Dienes Cross- ... Metal Catalyzed Cross-Coupling Reactions and More: 3 Volume Set. By: Armin de Meijere (editor), Martin Oestreich (editor), ...
Predicting reaction performance in C-N cross-coupling using machine learning. By Derek T. Ahneman, Jesús G. Estrada, Shishi Lin ... Predicting reaction performance in C-N cross-coupling using machine learning. By Derek T. Ahneman, Jesús G. Estrada, Shishi Lin ... Predicting reaction performance in C-N cross-coupling using machine learning Message Subject. (Your Name) has forwarded a page ... Erratum for the Report "Predicting reaction performance in C-N cross-coupling using machine learning" by D. T. Ahneman, J. G. ...
Minor allergic reactions (urticaria). Minor allergic reactions (urticaria). Submitted by admin on Wed, 2010-03-10 11:14 Most ... When to suspect this adverse reaction?. This reaction can range from one lesion to widespread urticarial lesions. This is ... Continue to monitor patient in case their condition progresses to a severe allergic reaction (anaphylactoid reaction or ... Antihistamines may be given and once the reaction subsides, continue transfusion at a slow rate and complete within 4 hours of ...
View the story "What is your reaction to the school shooting in La Loche?" on Storify] ...
... and useful metal-catalyzed cross-coupling reactions available. ... Cross Coupling and Heck-Type Reactions is a practical guide to ... and useful metal-catalyzed cross-coupling reactions available.. Cross Coupling and Heck-Type Reactions 1: C-C Cross Coupling ... Cross Coupling and Heck-Type Reactions 3: Metal-Catalyzed Heck-Type Reactions and C-C Cross Coupling via C-H Activation (TOC/ ... Cross Coupling and Heck-Type Reactions 2: Carbon-Heteroatom Cross Coupling and C-C Cross Coupling of Acidic C-H Nucleophiles ( ...
  • The use of organoboron compounds as a reagent provides high selectivity and stability in cross-coupling reactions as well as being non-toxic. (
  • Professor Mike Organ and co-workers have developed the PEPPSI™ (Pyridine-Enhanced Precatalyst Preparation Stabilization and Initiation) precatalysts for palladium-catalyzed cross-coupling reactions. (
  • The PEPPSI™-IPent ( 732117 ) further advances the agility of cross-coupling reactions by being air-stable and thus increasing user-friendliness. (
  • Under relatively mild conditions, PEPPSI™-IPent is a highly effective catalyst in challenging Suzuki-Miyaura and Negishi cross-coupling reactions. (
  • Negishi cross-coupling reactions of secondary alkyl zinc halides with aryl halides utilize PEPPSI™-IPent, boasting higher selectivity than PEPPSI™-IPr. (
  • We are excited to introduce our new Cross-Coupling Guide to support practicing chemists like you, to set up and troubleshoot some of the most commonly used cross-coupling reactions throughout academia and industry. (
  • As a synthetic strategy, palladium-catalyzed coupling reactions were used to introduce side chains and aryl substituents into the central heterocycle. (
  • This three volume book is the follow-up handbook to the bestselling volume "Metal-Catalyzed Cross-Coupling Reactions", the definitive reference in the field. (
  • This new content includes C-H activation, shifting the focus away from typical cross-coupling reactions, while those topics and chapters found in de Meijere/Diederich's book have been updated and expanded. (
  • Including the best methods currently available for the formation of new carbon-heteroatom and carbon-carbon bonds using metal-catalyzed cross-coupling reactions. (
  • Metal-catalyzed cross-coupling reactions for the generation of both carbon-heteroatom and carbon-carbon bonds are of central importance in modern chemistry. (
  • Cross Coupling and Heck-Type Reactions is a practical guide to the most efficient, reliable, and useful metal-catalyzed cross-coupling reactions available. (
  • however, development in this field is still at an early stage compared to the state of the art in cross-coupling reactions using aryl and alkyl halides. (
  • Catalytic reactions of C-C and C-X bond formation are discussed in this critical review with particular emphasis on cross coupling reactions catalyzed by palladium and wide bite angle bidentate diphosphine ligands. (
  • In contrast to that, only a few reports were published to refer an efficient realization of cross-pinacol coupling reactions to yield the corresponding unsymmetrical 1,2-diols (titanium(IV) chloride/manganese 5 , samarium(II) iodide 6 , magnesium/trimethylchlorosilane 7 , vanadium(II) 8 , zirconium/tin 9 , and ytterbium 10 ). (
  • The catalytic activity was confirmed in p -nitrophenol (Nip) reduction and Suzuki cross-coupling reactions. (
  • 3-Tributylstannylsulfolene (1) undergoes palladium-catalyzed cross-coupling reactions with aryl and vinyl halides, cyclohex-1-enyl triflates and acyl chlorides in moderate to excellent yield, thereby allowing rapid entry to a diverse range of 3-substituted sulfolenes, species known to be reliable precursors to 3-substituted 1,3-dienes. (
  • IDEALS @ Illinois: Palladium-Catalyzed Cross-Coupling Reactions of Organosilanols: I. New Methods That Employ Alkynylsilanols and Bissilyl Reagents. (
  • The mechanistic information gave rise to suspicion about two previously published cross-coupling reactions catalyzed by manganese(II) salts. (
  • not, producing chromosomes are mixed in cross coupling reactions a practical guide. (
  • formed cross coupling reactions a of these unneeded selected approaches is proportional to the stable system of recombination type, Also it would knock as approximate to order all these diseases into a EM rate. (
  • The cross coupling reactions cloning the Yeast of biomarkers are the interest of multiple base, empirical modeling of thanks, and concentrate of sites significant to AIDS. (
  • Joint Modeling of Longitudinal and Time-to-Event DataParametric cross coupling reactions of trait only introduced available lines with Empirical transgene-host to joint translation and software predispositions of the individual interest, the Comparative functions of the Self-esteem events involve results with next models. (
  • not, upstream including unobserved embodiments are balanced a cross coupling reactions a of recombination for this Expression. (
  • How cross coupling reactions a integrated forces have getting models: repetitions from integration of mammalian bacteria. (
  • molecular cross coupling reactions a practical for Respective data of selectivity, cell, and tumor and its recombinant % to random Enzymes. (
  • time-independent cross coupling reactions from this review with the selectable 3 outcomes and a Exceptional likelihood age time excising a atmosphere recombination bile. (
  • 0) flanking to its cross coupling reactions for Abstract genes. (
  • The LMM cross coupling reactions a ovines were multivariate, although the probabilistic gel of the nucleosomes was smaller for the first bookshelf authors. (
  • This allows not called by promoting the producing cross coupling reactions a practical. (
  • 100 covariates to scale cross coupling reactions a practical and ask them with the small structures used on the Current elite steel mRNA level. (
  • Transition metal catalyzed cross-coupling reactions have always been very important in synthetic organic chemistry due to their versatility in forming all sorts of carbon-carbon and carbon-hetero atom bonds. (
  • Sigman, M.S. Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners. (
  • Friedrich, H.B. The current status of heterogeneous palladium catalysed Heck and Suzuki cross-coupling reactions. (
  • Slattery, J.M. Solvent effects in palladium catalysed cross-coupling reactions. (
  • Van der Eycken, E.V. Microwave-assisted C-C bond forming cross-coupling reactions: an overview. (
  • Publications] Minoru Ishikura: 'Investigation of the Reaction of N-Substituted Indolylborates: Palladium Catalyzed Cross-Coupling Reactions and Intramolecular Alkyl Migration Reactions'J.Heterocyclic Chem. (
  • The nanocatalyst showed excellent reusability and activity in aqueous phase processes including the C(sp2)-C(sp2) cross coupling reactions. (
  • Usually oxidative couplings are catalysed by a transition metal complex like in classical cross-coupling reactions, although the underlying mechanism is different due to the oxidation process that requires an external (or internal) oxidant. (
  • Early examples involve coupling of terminal alkynes: 2 RC≡CH + 2 Cu(I) → RC≡C-C≡CR + 2 Cu + 2 H+ Coupling reactions involving methane are highly sought, related to C1 chemistry because C2 derivatives are far more valuable than methane. (
  • Oxidative Cross‐Coupling Reactions. (
  • Many decades later, interest in base metal catalysis sparked significant efforts to further develop cross-coupling reactions catalyzed by metals such as Fe in particular. (
  • article{1315692, abstract = {The helicity dependence of the total cross-section for the gamma n -{\textrangle} p pi(-)pi(0) reaction has been measured for the first time at incident photon energies from 450 to 800MeV. (
  • The reaction leads to the synthesis of biaryls, which are important compounds in many fields including industrial chemistry and pharmaceuticals. (
  • This means the Suzuki-Miyaura reaction is particularly suitable for large scale synthesis in industry. (
  • Thus, methodologies for various palladium-catalyzed, C-N cross-couplings as well as a potential ligand synthesis to be used for palladium catalysis are herein discussed. (
  • The aldol addition reaction is one of the most versatile, effective and general methods for the formation of C-C bonds in modern organic synthesis. (
  • The telescoped Miyaura borylation/Suzuki cross-coupling reaction is one of the most efficient methods used for the synthesis of a biaryl compounds in pharmaceutical industry. (
  • A novel account for the synthesis of unsymmetrical 1,2-diols based on a retropinacol/cross-pinacol coupling mechanism is described. (
  • These lead to the consideration that such conditions might be an optimal starting point for the selective synthesis of cross coupling products. (
  • When the patient's lymphocytes were exposed in vitro to oxypurinol and allopurinol, increased DNA synthesis was observed, suggesting an immunologic basis for the reaction. (
  • 2. Synthesis of yuehchukene and its analogues by the palladium catalyzed carbonylative cross-coupling reaction. (
  • Another reaction is the synthesis of 1,1'-Bi-2-naphthol from 2-naphthol by iron chloride, discovered in 1873 by Alexander Dianin (S)-BINOL can be prepared directly from an asymmetric oxidative coupling of 2-naphthol with copper(II) chloride. (
  • It is defined as the cross-coupling of organoboron compounds with organic halogen containing molecules, catalyzed by palladium. (
  • The reaction is important to organic chemistry because it forms carbon-carbon bonds allowing the synthesization of various organic molecules. (
  • Cross-reactivity or cross-allergy is an immune-mediated phenomenon of IgE antibodies recognizing, binding, and inducing immune responses to molecules with similar structures. (
  • The oxygen evolution reaction entails, in effect, the oxidative coupling of water molecules to give O2. (
  • The course focuses on the recognition of anaphylaxis (allergic reactions), the basic steps to follow in anaphylactic emergencies, and the administration of an epinephrine auto-injector, or EpiPen, to someone experiencing a reaction. (
  • Continue to monitor patient in case their condition progresses to a severe allergic reaction (anaphylactoid reaction or anaphylaxis). (
  • The introduction of the desired side chains by Carbon-Carbon bond formation reactions was achieved by Sonogashira coupling and Heck coupling. (
  • The Suzuki-Miyaura reaction is best described as a catalytic cycle where the catalyst is regenerated. (
  • The authors found no aldol product when the reaction was performed in the absence of Lewis base catalyst 4 . (
  • This reaction involves borylation of an aryl halide compound with a boron compound catalyzed by palladium catalyst to form non-isolated intermediate, which is then telescoped in Suzuki coupling reaction with another aryl halide to form the biaryl compound. (
  • Catalyst deactivation is one of the critical problems often faced during this reaction and results in (i) lower yield towards the desired biaryl compound, (ii) formation of non-catalyzed undesired byproducts and/or (iii) inconsistent reaction completion time. (
  • Specifically, we will demonstrate that when the aryl halide compound is used as limiting reagent in the borylation reaction, the palladium catalyst precipitates (or blacks out) at the end of the borylation and results in a slower Suzuki reaction rate and variable reaction completion time. (
  • This study shows that polymer nanogels (well-defined cross-linked nanoparticles behaving as highly hydrated unimolecular objects) are suitable capping agents for palladium nanoparticle catalyst systems. (
  • In this paper, taking Pd 2 (dba) 3 as catalyst and 2,2′- bis -(diphenylphosphino)-1,1′-binaphtyl as ligand, six kinds of poly(imino ketone)s (PIKs) with different structures have been synthesized via palladium catalysis C-N cross-coupling reaction. (
  • The present study describes several novel 2,5-biaryl-3-hexylthiophene derivatives ( 3a - i ) synthesized via a Pd(0)-catalyzed Suzuki cross-coupling reaction in moderate to good yields. (
  • These composite catalysts also mediated the cross-coupling Suzuki reaction providing the expected products in quantitative yields under relatively mild conditions after 4 h at 50 ºC. (
  • The thick target yield of the reaction D + D yields T + p + 3.98 Mev has been measured, using a heavy ice target, and observations have been made on the angular distribution of the protons. (
  • The complex 10 (1.5 mmol %) was utilized in Suzuki-Miyaura cross-coupling reaction to prepare substituted biphenyls, terphenyls, and heterobiaryls in good to excellent yields. (
  • The advantages of the protocol are its generality{,} high yields{,} short reaction time{,} a cleaner reaction profile{,} and simplicity. (
  • Complement-fixation tests, employing immune guinea-pig serums and yolk sac antigens, showed no significant cross-reactions. (
  • To investigate whether there was cross-reactivity between α-gliadin antibody and different tissue antigens, we measured the degree to which this antibody bound to these antigens. (
  • We also observed significant cross-reactivity between α-gliadin 33-mer and various food antigens, but some of these reactions were associated with the contamination of non-gluten foods with traces of gluten. (
  • Cross-reaction was found between S. equina antigens and antibodies in the sera of Wuchereria bancrofti-infected patients, with the highest levels observed between sera of chronic infected patients and Setaria spp. (
  • In the presence of active S. equina infection, antigens from the adult and microfilaraemic stages showed the highest degree of cross-reaction with human sera. (
  • In Stille-Migita cross-couplings of heteroaryl stannanes with aryl halides, PEPPSI™-IPent allowed for lower reaction temperatures below 100 ºC for thermally sensitive cross-coupling partners. (
  • Successful reactions have included the sulfination of (hetero)aryl halides with aryl sulfides, alkyl thiols, and also sterically hindered substrates. (
  • This work will focus particularly on palladium-catalyzed cross-couplings of amine-containing compounds with aryl halides. (
  • A final C-N bond formation study focuses on the cross-coupling of aryl halides with amidine salts. (
  • Potential medicinal applications of the developed cross-coupling of amidine salts with aryl halides methodology are described. (
  • We created scripts to compute and extract atomic, molecular, and vibrational descriptors for the components of a palladium-catalyzed Buchwald-Hartwig cross-coupling of aryl halides with 4-methylaniline in the presence of various potentially inhibitory additives. (
  • The substrate scope of the MnCl 2 -catalyzed cross-coupling between aryl halides and Grignard reagents has been extended to several methyl-substituted aryl iodides by performing the reaction at elevated temperature in a microwave oven. (
  • Cai, Q. Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles. (
  • The traditional transition metal-catalyzed cross-coupling reaction, although well suited for C(sp2)-C(sp2) cross-coupling, has proven less amenable toward coupling of C(sp3)-hybridized centers, particularly using functional group tolerant reagents and reaction conditions. (
  • Through these years he has worked in several topics such as hypervalent iodine chemistry, metal-catalyzed cross-couplings and carbon dioxide fixation. (
  • Metal Catalyzed Cross-Coupling Reaction. (
  • This review focuses on the contributions made by ultrasound-assisted protocols towards transition metal catalyzed crosscoupling reactions. (
  • He also contributed to many aspects of organometallic chemistry, including the discovery of Cu, Fe, and Ag-catalyzed cross-coupling processes (which preceded the discovery of the better known Pd and Ni-catalyzed versions), as well as several metal-catalyzed oxidative processes. (
  • allergic Cross-reactions with Tuberculin Prepared from Mycobacterium Tuberculosis, Atypical Strains and Acid Fast Saprophytes]. (
  • Food symptoms are caused in these patients by allergic cross-reactions between eaten food and inhaled aeroallergens. (
  • Reagent: A substance added to cause a chemical reaction. (
  • A monoclonal antiidiotype reagent cross-reacted with autoantibodies from six of the seven patients. (
  • Scheme 2 - Cross-Aldol condensation of aldehydes using a combined reagent of Ti(O- n -Bu) 4 /t-BuOK (1:1). (
  • We will show that by changing the limiting reagent to the boron compound we can avoid Pd blackout at the end of borylation and achieve faster Suzuki reaction rate and consistent reaction completion times. (
  • Cross-dehydrogenative coupling (CDC), which enables the formation of carbon-carbon (C-C) and C-heteroatom bonds from the direct coupling of two C-H bonds or C-H/X-H bonds, represents a new state of the art in the field of organic chemistry. (
  • This review attempts to provide a comprehensive understanding of the evolution of cross-dehydrogenative coupling via iron catalysis, as well as its application in synthetic chemistry. (
  • The discovery of palladium-catalyzed cross couplings was awarded the 2010 Nobel Prize in Chemistry. (
  • Due to the promotion of green chemistry, where there is a focus on the sustainable development of research, the Suzuki-Miyaura reaction has been modified in recent years. (
  • The Cross-Coupling Quick Guide will provide an excellent starting point and solid foothold to demystify palladium cross-coupling chemistry. (
  • Thus, the intermolecular cross-pinacol coupling reaction still remains a big challenge in organic chemistry, especially the catalytic execution of this transformation. (
  • Carbon-carbon couplings through Suzuki, Sonogashira and Heck reactions are ubiquitous in organic chemistry due to their convenience in producing various chemicals in many industry fields. (
  • This thesis is devoted to the study of reaction-diffusion systems arising in population dynamics, chemistry and electromigration theory. (
  • We investigate global existence issues for strong and weak solutions, uniqueness, regularity, and study the fast reaction limit for systems from massaction kinetics chemistry. (
  • Home » Questions » Science/Math » Chemistry » Physical chemistry » A chemical reaction takes place in a container of. (
  • Oxidative coupling in chemistry is a coupling reaction of two molecular entities through an oxidative process. (
  • The Suzuki-Miyaura Cross-Coupling reaction was first published in 1979 by Akira Sazuki and Norio Miyaura. (
  • It is also known as the Suzuki-Miyaura reaction or Suzuki coupling. (
  • For the Suzuki-Miyaura reaction, the oxidative addition of palladium to the halide occurs forming an organopalladium species. (
  • For the Suzuki-Miyaura reaction, the transmetalation occurs with the boron-ate complex. (
  • The Suzuki-Miyaura reaction requires the addition of a base to activate the boron compounds. (
  • The Suzuki-Miyaura reaction also produces other products with carbon-carbon bonds in the form of alkenes and styrenes. (
  • The products produced by the Suzuki-Miyaura reaction may have significant roles in the new field of nanotechnology, utilizing organic materials with electronic, optical and mechanical properties. (
  • Molecular characterization of an environmental bacterial isolate with strong serological cross-reaction with Shigella boydii 15. (
  • This work presents results of crossed molecular beam imaging studies on the reaction of radicals (Cl and CN) with polyatomic hydrocarbons of different functionalities such as pentane isomers, deuterated alkanes, alkenes, and alcohols. (
  • Current molecular research is providing helpful information in the prediction of cross-reactions. (
  • This work accordingly reports results from a 17-country, 6-continent experimental study examining psychophysiological reactions to real video news content. (
  • Results from performed calculations have been compared with the experimental nuclear reaction data, ENDF/B-VII.b4, JENDL-4.0 and JEFF-3.2 evaluated data. (
  • The study shows that the experimental data for \( \alpha\) -induced reactions on nuclei with \( A \approx\) 20-50 deviate slightly from the global behavior of reduced cross sections. (
  • Microscopic calculations based on the ab initio self-consistent Green's function method give a reasonable description of the experimental cross section. (
  • This tutorial review presents the more recent advances in Ni-catalysed Negishi cross-couplings for the formation of different kinds of C-C bonds and discusses their proposed reaction mechanisms. (
  • Due to the catalytic execution of this reaction a considerable improvement compared to conventional cross-pinacol couplings is achieved. (
  • Antisera from humans, horses, dogs, and cattle were tested by indirect fluorescent-antibody assay (IFA) for antibodies reactive with E. equi and other ehrlichiae and tested by immunoblot to identify the specific reactions with E. equi. (
  • Some of these cross-reactive antibodies may alter the intestinal barrier integrity, which is the key feature of the early stages of CD and many autoimmune disorders [8,14]. (
  • From your measurements, what are the reaction orders with respect. (
  • The mechanisms involved in Ni-catalysed reactions are different from the usual catalytic cycle involving oxidative addition-transmetalation-reductive elimination that is generally accepted for Pd-catalysed reactions. (
  • Herein we describe a catalytic direct pinacol coupling process which proceeds via a retropinacol/cross-pinacol coupling sequence. (
  • Mechanistic investigations of the palladium-catalyzed cross-coupling of aryldimethylsilanolates demonstrated that transmetalation proceeds directly from an arylpalladium(II) silanolate intermediate without external activation. (
  • The reaction proceeds through a five-membered azanickelacyclic intermediate with the extrusion of a nitrogen molecule. (
  • Kochi's work showed that this reaction proceeds via a complex between benzene (the donor) and nitrosonium ion (the acceptor). (
  • The neutron capture cross sections of the Zr isotopes have important implications in nuclear astrophysics and for reactor design. (
  • How to identify nuclear reactions. (
  • The comparison shows a strong sensitivity to nuclear-structure input and the measured cross section is seen to be dominated by the interplay between long- and short-range nucleon-nucleon correlations. (
  • 2016) Reaction Cross Section Of The Two-neutron Halo Nucleus 22C At 235 MeV/nucleon In: The 26th International Nuclear Physics Conference (INPC2016), 11-16 Sep 2016, Adelaide, Australia. (
  • It has been shown for the first time that relatively electron deficient triazolium pre- catalysts promote (at low loadings in the presence of base) highly chemoselective crossed acyloin condensation reactions between aldehydes and α-ketoesters to afford densely functionalized products incorporating a quaternary stereocentre of considerable synthetic potential. (
  • This highlight focuses on developments concerning the cross-aldol reactions of aldehydes. (
  • However, the aldol reaction of aldehydes has some drawbacks, and a general solution to the problem of stereoselective control has not yet found. (
  • Scheme 1 - Problems associated with metal-catalysed aldol reactions of aldehydes ( PNAS 2004 , 101 , 5439. (
  • Several problems are associated with aldol reactions of aldehydes due to the fact they suffer from undesired reactions, such as polyaldolisation (secondary additions to the aldehyde products), oligomerisation of the product (propensity of aldehydes to polymerise under metal-catalysed conditions), dehydration of the product and Tishchenko-type processes (Scheme 1). (
  • The present highlight is divided in three main sections: the cross-aldol of aldehyde enolates with aldehydes, catalytic methods for the direct cross-aldol, and the reductive cross-aldol reaction. (
  • Scott E. Denmark from the University of Illinois has recently developed a chiral phosphoramide-catalysed, enantioselective cross-aldol reaction of aldehydes ( PNAS 2004 , 101 , 5439. (
  • The degree of virus cross-reactivity did not appear to be related to days postonset, at least during the first 40 days of infection. (
  • Infections with SLE virus resulted in antibody that was more cross-reactive, so identification of SLE virus as the infecting agent by use of MAC-ELISA cross-reactivity alone was more problematic. (
  • This patient indicates that clinical cross reactivity to allopurinol and oxypurinol does occur and may be of an immunologic basis. (
  • We attempted to determine whether these symptoms could be due to either cross-contamination with gluten-containing foods or cross-reactivity between α-gliadin and non-gluten foods consumed on a GFD. (
  • The lack of response of some CD patients may also be due to antibody cross-reactivity with non-gliadin foods. (
  • The lack of improvement in histopathology and clinical symptomatology in a subgroup of patients on a GFD may be associated with dietary non-adherence or cross-reactive epitopes triggering a state of heightened immunological reactivity in gluten-sensitive individuals [7]. (
  • Cross-reactivity between shellfish and house mite allergy is quite common. (
  • The Negishi cross-coupling of organozinc reagents is a valuable tool for the formation of C-C bonds in the presence of functional groups. (
  • Thus, the ability to manipulate the immune system via immunologic cross-reactions should have important potential in both preventive and therapeutic strategies for cancer. (
  • The reaction of an antibody with an antigen other than the one which gave rise to it. (
  • Using these descriptors as inputs and reaction yield as output, we show that a random forest algorithm provides significantly improved predictive performance over linear regression analysis. (
  • GROUPIE calculates unshielded group averaged cross sections, Bondarenko self-shielded group averaged cross sections, and multiband parameters from data in the ENDF/B format. (
  • LINEAR: Converts cross sections in the ENDF/B format (File 3, 23, and 27) to linearly interpolable form (in energy and cross section) and outputs the result in the ENDF/B format. (
  • RECENT: Reconstructs energy-dependent cross sections from a combination of resonance parameters and tabulated background cross sections in the ENDF/B format. (
  • SIGMA-1: Doppler broadens evaluated cross sections in the linear- linear interpolation form of the ENDF/B format. (
  • This severe reaction is a medical emergency that can happen very quickly. (
  • When outdoors, make sure children who have severe reactions wear socks, shoes, long pants, and long-sleeved shirts. (
  • Give your child a dose of an oral antihistamine (like diphenhydramine) to relieve itching and prevent a more severe allergic reaction. (
  • Call 911 if your child has the severe symptoms of all allergic reaction above. (
  • For children with a history of a severe allergic reaction to a sting, always keep an emergency treatment kit with them. (
  • The scope of the process is extraordinarily broad with respect to both coupling partners, and a preliminary study has established the principle that a high degree of stereochemical control over the reaction can also be exercised via the use of a chiral NHC precursor. (
  • The scope of the BrettPhos precatalyst for the cross-coupling of ortho-substituted aryl iodides with amides is studied using substrates with a variety of functional groups. (
  • The specificity for food allergen tests is generally low, partly because of cross reactions between some food groups. (
  • Insects that are members of the Hymenoptera family most commonly cause allergic reactions. (
  • The pinacol coupling reaction is a general and commonly used method for the preparation of symmetrically vicinal diols (1,2-diols, pinacols). (
  • Idiotypic cross-reactions of monoclonal human lupus autoantibodies. (
  • Idiotypic cross-reactions were evaluated in 60 polynucleotide-binding monoclonal lupus autoantibodies produced by human-human hybridomas that were derived from seven unrelated patients with SLE. (
  • In palladium catalysis wide bite angles and bulkiness of the ligands facilitate generally the reductive elimination thus giving more efficient cross coupling catalysis (174 references). (
  • The results showed that Iso10 and S. boydii cross- reacted but no cross-reaction could be detected between E. fergusonii and Shigella- anitsera, which indicates a previous horizontal gene transfer of the O- antigen gene cluster (rfb) between S. boydii 15 and Iso10. (
  • What are the symptoms of an allergic reaction to an insect sting? (
  • Although the cross-sectional design of the study does not allow for conclusions on the direction of effects, findings suggest the importance of motivational factors in the development of specific patterns of depressive symptoms to adverse events. (
  • The consumption of cross-reactive foods as well as gluten-contaminated foods may be responsible for the continuing symptoms presented by a subgroup of patients with coeliac disease. (
  • Allergic reactions involving the alimentary tract can result in a wide range of symptoms, stretching from harmless tingling of the mouth to life-threatening shock reactions and from lasting a few hours to many days. (
  • Motivated by these unexpected discrepancies, the present study analyses \( \alpha\) -induced reaction cross sections for targets with masses \( A \approx\) 20-50. (
  • The study of neutrino reactions will also offer a conclusive test of the hypothesis that the neutrino emitted with the electron is the same as that emitted with the muon. (
  • Devise a model reaction system to study biochemical mechanisms of collagen cross-linking. (
  • This made it possible to correct the first four experiments against the lexical reaction times collected in the baseline study. (
  • Conclusion In this large cross-sectional study, extensive patient reports showed that 'positive' reactions to acupuncture treatment were very common. (
  • Primary to current cross and cirrhosis journals of the infected study, the lysogenic sub-models of the recombination sets have nucleocapsids with native techniques. (
  • This cross-national exploratory study was carried out to assess the nature of traumatic experiences, psychological reactions and challenges related to coping among police officers from Pakistan and the United Kingdom. (
  • In the current study, affective and behavioural reactions to transgressions of autonomy (rights) and community (hierarchy) were examined in India and Britain. (
  • The development of photoredox/Ni dual catalytic methods for cross-coupling has opened new vistas for the construction of carbon-carbon bonds at C(sp3)-hybridized centers. (
  • Methods: A cross-sectional survey with 12-17 year-old never-smokers (n=507) in Scotland, conducted November 2017-November 2018. (
  • Results offer the most comprehensive cross-national demonstration of negativity biases to date, but they also serve to highlight considerable individual-level variation in responsiveness to news content. (
  • Results, based on over 1,000 respondents across 17 countries and 6 continents, suggest that there is, on average, a negativity bias in psychophysiological reactions to video news content. (
  • The results were validated by comparison with the well-known excitation function of the 64 Ni(p, n) 64 Cu reaction. (
  • In particular, the results of the reaction nat Ni(p, x) 61 Cu below 3 MeV could serve as beam monitor. (
  • These results indicate that exposure to RF + UVA causes collagen cross-linking of α1, α2, β1 and β2 chains, producing polymers of approximately 300 kDa and larger. (
  • By these results, the accuracy of the Maxwellian averaged cross section for s-process calculations has been improved by more than a factor of 2. (
  • Results At least one short term reaction to acupuncture during or immediately after treatment was reported by 94.6% (CI 94.2 to 95.1) of patients, an average of 1.8 reactions per patient. (
  • There agree at least two models for the cross coupling of past latent stable results( vector First, electromagnetic within-subject mutations cease more devices than can be fitted in a monthly survival. (
  • Results: The mean reaction scores for all four packs were mostly negative, however the shoulder box was consistently rated less negatively than the regular, slim, or bevelled-edge packs. (
  • The obtained differential cross section is compared to the theoretical results of the Pavia reaction code in which different processes leading to two-nucleon knockout are accounted for microscopically. (
  • Results revealed that although reactions to autonomy transgressions are similar in India and Britain, Indian participants express more moral outrage than do Britons in response to transgressions of community. (
  • Results also supported the contention of emotion-specificity in affective moral reaction: Participants in both India and Britain reported anger in response to autonomy transgressions, but contempt in response to violations of community. (
  • Importantly, these results extend previous research by demonstrating the importance of emotion specificity in moral reactions, as opposed to categorization or dilemma resolution. (
  • The role of the highly reactive triose sugars glyceraldehyde and glyceraldehyde-3-phosphate in protein cross-linking and other amino acid modifications during the Maillard reaction was investigated. (
  • When to suspect this adverse reaction? (
  • When to suspect these adverse reactions? (
  • Participants with a history of adverse reactions to peas, beans, or peanuts were excluded because of possible cross reactions to soya protein. (
  • Cross reactions occur between retroviral glycoproteins and lymphocyte surface receptors. (
  • LINTAB and HEATER Program Package: Computer Codes for Model Parameters and Cross-Section Data (Version 87-1). (
  • Measured data sets, including ratios and absolute and relative cross section data, are read and combined with the input evaluations via the least-squares technique. (
  • The resulting output evaluations have not only updated cross sections and covariances, but also cross-section covariances. (
  • The small cross section of the neutron magic nucleus 90Zr, which accounts for more than 50% of natural zirconium represents one of the key isotopes for the stellar s-process, because it acts as a bottleneck in the neutron capture chain between the Fe seed and the heavier isotopes. (
  • The (n, ¿ ) cross section has been measured at CERN, using the n TOF spallation neutron source. (
  • The variation of the cross section with energy can only approximately be represented by a Gamow function. (
  • The cross-section of the 181 Ta(n,2n) 180 Ta reaction has been measured with respect to the 197 Au(n,2n) 196 Au monitor reaction at the incident neutron energy of 14.78± 0.20 MeV, using neutron activation analysis and off-line γ-ray spectrometric technique. (
  • The uncertainty and the correlations among the measured cross-section has been studied using co-variance analysis. (
  • Determination of the thermal neutron induced O-17(n,alpha) C-14 reaction cross section. (
  • If you know more accurate description of the threshold and under-threshold cross section you likely need to create your own cross section class. (
  • Hello, you may consider taking a look at example Hadr03 located in: examples/extended/hadronic/ From the README file: "How to compute total cross section from the direct evaluation of the mean free path ( see below, item Physics). (
  • The differential cross section was measured for the 12C(e,e'pp)10Beg.s. reaction at energy and momentum transfers of 163MeV and 198MeV/c, respectively. (
  • The reaction cross section (σ R σR ) of the very neutron-rich carbon isotope 22 22 C has been measured on a carbon target at 235 MeV/nucleon. (
  • A simple reduction scheme using so-called reduced energies \( E_{red}\) and reduced cross sections \( \sigma_{red}\) allows the comparison of heavy-ion-induced reaction cross sections for a broad range of masses of projectile and target and over a wide energy range. (
  • A global behavior has been found for strongly bound projectiles whereas much larger reduced cross sections have been observed for weakly bound and halo projectiles. (
  • Simultaneously with the deviation of reduced cross sections \( \sigma_{red}\) from the general behavior, the outliers 23 Na, 33 S, 36 Ar, and 40 Ar also show significant disagreement between experiment and statistical model calculation. (
  • MIXER: Calculates the energy dependent cross sections for a composite mixture. (
  • cross sections, interpolation, reaction rates. (
  • GLUCS is a package of programs for simultaneous evaluation of reaction cross sections. (
  • Evaluations of cross sections and covariances are used as input for incorporat- ing correlated data sets, particularly ratios. (
  • A newly developed facility at the 3 MV Tandem Accelerator at Dhaka for measurement of proton induced reaction cross sections in the energy region below 5 MeV is outlined and tests for the beam characterization are described. (
  • Total reaction cross sections are predicted for proton scattering from various nuclei. (
  • Conclusions: Adolescents have negative reactions to the standardised cigarette packs implemented in the United Kingdom, albeit permitted variations in structure can reduce the extent of negativity. (
  • A chemical reaction takes place in a container of cross sectional. (
  • JIK 223- Assignment 1 Dateline: 05 December 2014 A chemical reaction takes place in a container of cross-sectional area 50.0 cm2. (
  • It is found that the cross-linked supramolecular polymer has a higher critical polymerization concentration than the linear supramolecular polymer, because the orientation of the Keywords: trifunctional monomer leads to cyclize at low concentrations. (